CN105456624A - Traditional Chinese medicine caring composition for post-partum recovery and preparation method thereof - Google Patents
Traditional Chinese medicine caring composition for post-partum recovery and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine caring composition for post-partum recovery and a preparation method thereof. The traditional Chinese medicine caring composition is prepared from the following raw materials: viburnum taitoense hayata, root of twocolor velvetplant, Euonymus semenovii Regel et Herd., Panzeria alashanica Kupr., faeces of Ochotona thibetana (Milne-Edwards), padix panacis pseudoginseng, root of Chinese loropetalum, potentilla bifurca L, goat spinal cord, Clitoria mariana L., euonymus myrianthus, rubia yunnanensis (Franch.) Diels, ginkgoroot, Lindernia ciliata (Colsm.) Pennell [Ilysanthes serrata (Roxb.) Urban], sedum amplibracteatum K.T.Fu [S.bracteatum Diels], herba stellariae neglectae and Dioscorea esquirolii Prain et Burkill. The traditional Chinese medicine caring composition for post-partum recovery has the effects of replenishing qi and nourishing blood, cooling blood and stopping bleeding, dispersing blood stasis and relieving pain, as well as resisting bacteria and diminishing inflammation, has remarkable curative effects for post-partum body recovery and caring of pregnant women, is low in cot, mild in properties, and free of toxic and side effects, and belongs to an ideal post-partum care medicine.
Description
Technical field
The present invention relates to technical field of Chinese medicines, particularly relate to a kind of Chinese medicine nursing composition and method of making the same for postpartum recovery.
Background technology
Postpartum recovery refers to that women is after production is complete, usually can need certain recovery and maintenance because health is too weak.General female clinical multilist in puerperal reveals blood, anemia, sweating due to debility, blood stasis, infection, lochiorrhea, hypogalactia, waist abdomen pain, postpartum depression, sends out the symptom in various degree such as convulsion, difficulty in defecation, very just puerperal fever can not be left, as puerperal infection, arthralgia, depression of liver-QI etc. if any maintenance.Traditional Chinese medical science postpartum recovery is for the feature of women's physiological and pathological in puerperal, often select Herba Leonuri, Radix Polygoni Multiflori, Radix Angelicae Sinensis etc., molten nourishing the liver and kidney, benefiting QI and nourishing blood, regulating qi-flowing for strengthening spleen, blood circulation promoting and blood stasis dispelling are in a stove, regulate puerpera's metabolism, promote the rehabilitation of body in puerperal, in the hope of reaching promotion uterine involution, muscle fiber attenuated, buckling of vessel reduces, mucomembranous gland is more complete, improve human body immune function, improve blood phase, remove the effect of the turbid liquid of uterine cavity blood stasis and promotion ovarian function recovery.
The nursing medicine of postpartum recovery has much in recent years, and Chinese medicine has unique effect, and a large amount of clinical practices confirms, Chinese medicine few side effects, safety is high, has the advantage of Mutiple Targets too many levels, can improve the clinical symptoms of puerpera.But some Chinese medicine preparation, although cheap, side effect is little, and effect is single, and the course for the treatment of is grown and easily recurs.
Summary of the invention
For above Problems existing, the invention provides a kind of evident in efficacy, with low cost, and the property of medicine is gentle, without any side effects, the nursing medicine of ideal postpartum recovery.
Another object of the present invention is to provide a kind of preparation method of the Chinese medicine nursing compositions for postpartum recovery.
Technical scheme of the present invention is: a kind of Chinese medicine nursing compositions for postpartum recovery, and raw material and weight portion thereof are: to leaf Oleum Sesami root 40-56 part, Radix Gynurae bicoloris 35-50 part, Xinjiang winged euonymus 32-48 part, Herba leonuri pseudoma cranthi 30-44 part, Ochotonathibetana Milne-Edwards 28-40 part, hide Radix Notoginseng 26-38 part, Radix Loropetali 25-36 part, two decomposite leaf Herba Potentillae Chinensis 22-34 parts, Medulla caprae seu ovis 20-33 part, mountain bean 18-32 part, Radix Euonymi myrianthi 16-30 part, Rubiayunnanensis (Franch.) Dlels 15-28 part, Radix Ginkgo 12-26 part, alpine yarrow 10-23 part, lamp-stand dish 8-20 part, Herba Stellariae Neglectae 6-14 part, potato 4-10 part of enriching blood.
Further, described a kind of Chinese medicine nursing compositions for postpartum recovery, raw material and weight portion thereof are: to leaf Oleum Sesami root 48 parts, Radix Gynurae bicoloris 42.5 parts, Xinjiang winged euonymus 40 parts, Herba leonuri pseudoma cranthi 37 parts, Ochotonathibetana Milne-Edwards 34 parts, hide Radix Notoginseng 32 parts, Radix Loropetali 30.5 parts, two decomposite leaf Herba Potentillae Chinensis 28 parts, Medulla caprae seu ovis 26.5 parts, mountain bean 25 parts, Radix Euonymi myrianthi 23 parts, Rubiayunnanensis (Franch.) Dlels 21.5 parts, Radix Ginkgo 19 parts, alpine yarrow 16.5 parts, lamp-stand dish 14 parts, Herba Stellariae Neglectae 10 parts, potato 7 parts of enriching blood.
Further, described Xinjiang winged euonymus and Tibetan Radix Notoginseng need infusing drugs in wine, make ingredient fully leach rear extraction.
Another object of the present invention is to provide a kind of preparation method of the Chinese medicine nursing compositions for postpartum recovery, comprises the following steps:
(1) take leaf oil Radix Cannabis, Radix Gynurae bicoloris, Ochotonathibetana Milne-Edwards, Radix Loropetali, mountain bean, Bletilla striata (Thunb.ex A.Murray)Rchb.f. fruit by described proportioning, remove impurity, becomes coarse powder with pulverizer powder after drying, cold water soaks 30-50 minute, add water and do not have medicated powder 4cm, after very hot oven boils, change slow fire boiling 2-3 hour, extract; Add water and do not have medicinal residues 2.5cm, very hot oven boils, and turns slow fire boiling 20-30 minute, extracts; Merge extractive liquid, adds 1-2 times of ethanol, mix homogeneously, placement is spent the night, and makes it precipitate filter, gets supernatant, the a small amount of 50%-60% ethanol of precipitate is cleaned, washing liquid and filtrate merge, decompression recycling ethanol, and precipitation is completely rear filters, filtrate is concentrated into the thick extractum of relative density 1.30-1.35 at 40 DEG C, for subsequent use; ;
(2) take Xinjiang winged euonymus by described proportioning, hide Radix Notoginseng, add the yellow wine sealing that alcohol content is 20%, soak at room temperature extracts 2-3 time, each soak time is one week, make effective ingredient fully leach hypsokinesis and get supernatant, filter, it is the extractum of 0.96-1.22 that normal pressure concentrates 16 hours obtained relative concentrations, for subsequent use;
(3) Herba leonuri pseudoma cranthi, two decomposite leaf Herba Potentillae Chinensis, Medulla caprae seu ovis, Radix Euonymi myrianthi, the western regions of the Yunnan Province grass, lamp-stand dish, potato of enriching blood is taken by described proportioning, clean, insert in marmite and add 6-8 times of pure water decoction, first very hot oven decocts 30 minutes, then changes slow fire 50 minutes, extract 3 times, filter, merging filtrate, adopts spray drying technology to make extract powder filtrate, 140 orders sieve for subsequent use;
(4) take alpine yarrow and Herba Stellariae Neglectae fresh goods by described proportioning, wash clean, smashes juice, leaches impurity, and add 2-3 times of cold water, heated and boiled, slow fire is endured to paste, for subsequent use;
(5) fine powder that extractum extractum obtained for step (1), step (2) obtained, step (3) obtain is mixed homogeneously with the thick paste that step (4) obtains, and obtains the Chinese medicine nursing composite preparation of the present invention for postpartum recovery.
Further, described medicine is added pharmacy customary adjuvant and make granule or pill.
Wherein, the preparation method of described granule is:
(1) take leaf oil Radix Cannabis, Radix Gynurae bicoloris, Ochotonathibetana Milne-Edwards, Radix Loropetali, mountain bean, Bletilla striata (Thunb.ex A.Murray)Rchb.f. fruit by described proportioning, remove impurity, becomes coarse powder with pulverizer powder after drying, cold water soaks 30-50 minute, add water and do not have medicated powder 4cm, after very hot oven boils, change slow fire boiling 2-3 hour, extract; Add water and do not have medicinal residues 2.5cm, very hot oven boils, and turns slow fire boiling 20-30 minute, extracts; Merge extractive liquid, adds 1-2 times of ethanol, mix homogeneously, placement is spent the night, and makes it precipitate filter, gets supernatant, the a small amount of 50%-60% ethanol of precipitate is cleaned, washing liquid and filtrate merge, decompression recycling ethanol, and precipitation is completely rear filters, filtrate is concentrated into the thick extractum of relative density 1.30-1.35 at 40 DEG C, for subsequent use;
(2) take Xinjiang winged euonymus by described proportioning, hide Radix Notoginseng, add the yellow wine sealing that alcohol content is 20%, soak at room temperature extracts 2-3 time, each soak time is one week, make effective ingredient fully leach hypsokinesis and get supernatant, filter, it is the extractum of 0.96-1.22 that normal pressure concentrates 16 hours obtained relative concentrations, for subsequent use;
(3) Herba leonuri pseudoma cranthi, two decomposite leaf Herba Potentillae Chinensis, Medulla caprae seu ovis, Radix Euonymi myrianthi, the western regions of the Yunnan Province grass, lamp-stand dish, potato of enriching blood is taken by described proportioning, wash clean, 30 minutes are decocted with the first very hot oven of soak by water, change slow fire again 50 minutes, extract 3 times, filter, merging filtrate, adopt spray drying technology to make extract powder filtrate, 140 orders sieve for subsequent use;
(4) take alpine yarrow and Herba Stellariae Neglectae fresh goods by described proportioning, wash clean, smashes juice, leaches impurity, and add 2-3 times of cold water, heated and boiled, slow fire is endured to paste, for subsequent use;
(5) by extractum obtained for step (1), the extractum that step (2) is obtained, the thick paste that the fine powder that step (3) obtains obtains with step (4) is mixed homogeneously, obtain mixture, cold drying, prepare the technological requirement of granule and adjuvant requirement by pharmacy routine and add lactose relative to described mixture weight 5%, the polyvinylpyrrolidone of 1%, the microcrystalline Cellulose of 5%, the xylitol of 0.02%, the aminoacids complex of 0.3%, the compound vitamin mix homogeneously of 0.08%, after direct weighting is compressed into larger tablet, be ground into granule again, pack, obtain granule.
Wherein, the preparation method of described pill is:
(1) take leaf oil Radix Cannabis, Radix Gynurae bicoloris, Ochotonathibetana Milne-Edwards, Radix Loropetali, mountain bean, Bletilla striata (Thunb.ex A.Murray)Rchb.f. fruit by described proportioning, remove impurity, becomes coarse powder with pulverizer powder after drying, cold water soaks 30-50 minute, add water and do not have medicated powder 4cm, after very hot oven boils, change slow fire boiling 2-3 hour, extract; Add water and do not have medicinal residues 2.5cm, very hot oven boils, and turns slow fire boiling 20-30 minute, extracts; Merge extractive liquid, adds 1-2 times of ethanol, mix homogeneously, placement is spent the night, and makes it precipitate filter, gets supernatant, the a small amount of 50%-60% ethanol of precipitate is cleaned, washing liquid and filtrate merge, decompression recycling ethanol, and precipitation is completely rear filters, filtrate is concentrated into the thick extractum of relative density 1.30-1.35 at 40 DEG C, for subsequent use;
(2) take Xinjiang winged euonymus by described proportioning, hide Radix Notoginseng, add the yellow wine sealing that alcohol content is 20%, soak at room temperature extracts 2-3 time, each soak time is one week, make effective ingredient fully leach hypsokinesis and get supernatant, filter, it is the extractum of 0.96-1.22 that normal pressure concentrates 16 hours obtained relative concentrations, for subsequent use;
(3) Herba leonuri pseudoma cranthi, two decomposite leaf Herba Potentillae Chinensis, Medulla caprae seu ovis, Radix Euonymi myrianthi, the western regions of the Yunnan Province grass, lamp-stand dish, potato of enriching blood is taken by described proportioning, wash clean, 30 minutes are decocted with the first very hot oven of soak by water, change slow fire again 50 minutes, extract 3 times, filter, merging filtrate, adopt spray drying technology to make extract powder filtrate, 140 orders sieve for subsequent use;
(4) take alpine yarrow and Herba Stellariae Neglectae fresh goods by described proportioning, wash clean, smashes juice, leaches impurity, and add 2-3 times of cold water, heated and boiled, slow fire is endured to paste, for subsequent use;
(5) by extractum obtained for step (1), the extractum that step (2) is obtained, the thick paste that the fine powder that step (3) obtains is obtained with step (4) and described adjuvant are mixed homogeneously, obtain mixture, prepare the technological requirement of pill and adjuvant requirement by pharmacy routine and add lactose relative to described mixture weight 3%, the polyvinylpyrrolidone of 8%, the microcrystalline Cellulose of 5%, the xylitol of 0.01%, the aminoacids complex of 0.2%, the compound vitamin of 0.2%, the glycerol mix homogeneously of 20%, certain hour placed by the dough sample soft material got togather, pill made by craft or pill plate, dry, encapsulation, obtain pill.
The mixture that described aminoacids complex is made up of according to the mass ratio of 1:3 tyrosine, glutamic acid.The mixture that described compound vitamin is made up of according to the mass ratio of 1:2:5 vitamin C, vitamin B6, vitamin K.Lactose is soluble in water, stable in properties, no hygroscopicity, as filler; Polyvinylpyrrolidone-K30 is binding agent; Microcrystalline Cellulose disintegrating agent, dissolves rapidly after promoting medicine entrance; Xylitol, as correctives, can improve the bitterness of Chinese herbal medicine; Aminoacids complex and compound vitamin can improve the immunocompetence of body, strengthen alimentation, promote postpartum recovery; Glycerol is lubricant, the sticky hands of medicine group and sticking device tool when can avoid pill agent.
The pharmacologically active of each raw material of Chinese medicine of the present invention is as follows:
To leaf oil Radix Cannabis: [nature and flavor] taste is micro-sweet; Cool in nature.[function cures mainly] menstruction regulating and pain relieving.Abdominal pain due to blood stasis after main product; Dysmenorrhea.
Radix Gynurae bicoloris: [nature and flavor] are lightly seasoned, warm in nature, nontoxic.[function cures mainly] promoting flow of QI and blood.Stasis of blood stomachache is stopped, snowslide, malaria after managing property.
Xinjiang winged euonymus: [nature and flavor] are bitter, cold.[function cures mainly] promoting blood circulation to restore menstrual flow; Blood-activating analgetic; Removing toxic substances and promoting subsidence of swelling.Main amenorrhea; Postnatal blood stasis is suffered from abdominal pain; Arthralgia; Carbuncle sore is red and swollen.
Herba leonuri pseudoma cranthi: [nature and flavor] are pungent, bitter in the mouth is flat.[function cures mainly] regulating menstruation and activating blood, clearing away heat and promoting diuresis.For puerperal abdonimal pain, menoxenia, acute nephritis, metrorrhagia, mastitis, erysipelas, furuncle and phyma
Ochotonathibetana Milne-Edwards: [nature and flavor] are bitter salty, temperature, nontoxic.[function cures mainly] stimulates the menstrual flow, blood stasis dispelling.Control menoxenia, puerperal abdonimal pain, injury from falling down and blood stasis stagnate.
Hide Radix Notoginseng: [nature and flavor] mildly bitter flavor; Sweet; Warm in nature.[function cures mainly] removing stasis to stop bleeding; Subduing swelling and relieving pain.Main haematemesis; Epistaxis; Dysentery; Metrorrhagia; Prolonged lochia; Traumatic injury.
Radix Loropetali: [nature and flavor] slightly warm in nature, bitter and puckery flavor.[function cures mainly] controls hemoptysis, and stomachache is had loose bowels, proctoptosis, and podomere is ached, leucorrhea, and lochia is not smooth, and traumatic injury is spitted blood, toothache.
Two decomposite leaf Herba Potentillae Chinensis: [nature and flavor] are sweet, micro-pungent, cool.[function cures mainly] stops blooding, dysentery relieving.For dysfunctional uterine hemorrhage, postpartum hemorrhage is too much, dysentery.
Medulla caprae seu ovis: [nature and flavor] sweet in the mouth, temperature, nontoxic.[function cures mainly] tonifying YIN mends marrow, lung moistening pool flesh.Control asthenia thin and weak, consumptive lung disease, hectic fever due to YIN-deficiency, cough, quenches one's thirst, withered skin and hair, carbuncle, skin infection, conjunctival congestion, corneal nebula.
Mountain bean: [nature and flavor] are sweet, temperature.[function cures mainly] the kidney invigorating, hemostasis, relaxing muscles and tendons.Cure mainly flu, dizziness of suffering from a deficiency of the kidney, leucorrhea, puerperal abdonimal pain, edema, enterorrhagia, rheumatic arthritis.
Radix Euonymi myrianthi: [nature and flavor] are sweet; Micro-hardship; Flat.[function cures mainly] kidney tonifying strengthens waist; Blood stasis dispelling dampness removing.Main lumbago due to renal deficiency; Frequent fetal movement; Chronic nephritis; Prolonged lochia; Injury and bone fracture; Rheumatic arthralgia.
Rubiayunnanensis (Franch.) Dlels: [nature and flavor] are sweet is flat.[function cures mainly] is enriched blood and is invigorated blood circulation, expelling wind and removing dampness, softening the hard mass removing mass.Cure mainly anemia, traumatic injury, chronic gastritis, lipoma, menoxenia.
Radix Ginkgo: [nature and flavor] are sweet; Warm in nature.[function cures mainly] QI invigorating tonify deficiency.Main seminal emission; The enuresis; Night is frequently many, leucorrhea, stranguria caused by urinary stone.
Alpine yarrow: [nature and flavor] are lightly seasoned; Property is put down.[function cures mainly] heat-clearing and toxic substances removing; Removing blood stasis to reduce swelling.Main venom; Furuncle toxic swelling; Traumatic injury; Puerperal abdonimal pain.
Lamp-stand dish: [nature and flavor] are sweet; Light; Cold.[function cures mainly] heat-clearing and toxic substances removing; Blood circulation promoting competent silt.Main puerperal abdonimal pain; Stomachache; Constipation due to dry stool; Burn and scald.
Herba Stellariae Neglectae: [function cures mainly] anti-inflammation.Control toothache, furuncle and phyma, mastitis.
To enrich blood potato: [nature and flavor] are pungent; Micro-sweet; Cool.[function cures mainly] removing stasis to stop bleeding; Reducing swelling and alleviating pain.Main impairment of the lung caused by overstrain hemoptysis; Hepatosplenomegaly; Dysmenorrhea; Puerperal abdonimal pain; Traumatic injury.
Beneficial effect of the present invention is embodied in: a kind of Chinese medicine preparation for postpartum recovery of the present invention, there is effect of benefiting qi and nourishing blood, cooling blood for hemostasis, blood-activating analgetic, anti-inflammation, evident in efficacy, and it is with low cost, the property of medicine is gentle, without any side effects, be used for the treatment of the symptoms such as puerperal abdonimal pain, hemorrhage, lochia non-stop and weakness, promote puerpera's physical rehabilitation and maintenance.
Detailed description of the invention
Below in conjunction with concrete embodiment, Chinese medicine composition of the present invention is described in more detail:
Embodiment 1:
For a Chinese medicine nursing compositions for postpartum recovery, raw material and weight portion thereof are: to leaf Oleum Sesami root 40 parts, Radix Gynurae bicoloris 35 parts, Xinjiang winged euonymus 32 parts, Herba leonuri pseudoma cranthi 30 parts, Ochotonathibetana Milne-Edwards 28 parts, hide Radix Notoginseng 26 parts, Radix Loropetali 25 parts, two decomposite leaf Herba Potentillae Chinensis 22 parts, Medulla caprae seu ovis 20 parts, mountain bean 18 parts, Radix Euonymi myrianthi 16 parts, Rubiayunnanensis (Franch.) Dlels 15 parts, Radix Ginkgo 12 parts, alpine yarrow 10 parts, lamp-stand dish 8 parts, Herba Stellariae Neglectae 6 parts, potato 4 parts of enriching blood.
Preparation method is:
(1) take leaf oil Radix Cannabis, Radix Gynurae bicoloris, Ochotonathibetana Milne-Edwards, Radix Loropetali, mountain bean, Bletilla striata (Thunb.ex A.Murray)Rchb.f. fruit by described proportioning, remove impurity, becomes coarse powder with pulverizer powder after drying, cold water soaks 30 minutes, add water and do not have medicated powder 4cm, change slow fire boiling after very hot oven boils 2 hours, extract; Add water and do not have medicinal residues 2.5cm, very hot oven boils, and turns slow fire boiling 20 minutes, extracts; Merge extractive liquid, adds 1 times of ethanol, mix homogeneously, and placement is spent the night, and makes it precipitate filter, get supernatant, cleaned by a small amount of 50% ethanol of precipitate, washing liquid and filtrate merge, decompression recycling ethanol, precipitation is completely rear filters, and filtrate is concentrated into the thick extractum of relative density 1.30 at 40 DEG C, for subsequent use;
(2) take Xinjiang winged euonymus by described proportioning, hide Radix Notoginseng, add the yellow wine sealing that alcohol content is 20%, soak at room temperature extracts 2 times, each soak time is one week, make effective ingredient fully leach hypsokinesis and get supernatant, filter, it is the extractum of 0.96 that normal pressure concentrates 16 hours obtained relative concentrations, for subsequent use;
(3) Herba leonuri pseudoma cranthi, two decomposite leaf Herba Potentillae Chinensis, Medulla caprae seu ovis, Radix Euonymi myrianthi, the western regions of the Yunnan Province grass, lamp-stand dish, potato of enriching blood is taken by described proportioning, wash clean, 30 minutes are decocted with the first very hot oven of soak by water, change slow fire again 50 minutes, extract 3 times, filter, merging filtrate, adopt spray drying technology to make extract powder filtrate, 140 orders sieve for subsequent use;
(4) take alpine yarrow and Herba Stellariae Neglectae fresh goods by described proportioning, wash clean, smashes juice, leaches impurity, and add 2-3 times of cold water, heated and boiled, slow fire is endured to paste, for subsequent use;
(5) by extractum obtained for step (1), the extractum that step (2) is obtained, the thick paste that the fine powder that step (3) obtains obtains with step (4) is mixed homogeneously, obtain mixture, cold drying, prepare the technological requirement of granule and adjuvant requirement by pharmacy routine and add lactose relative to described mixture weight 5%, the polyvinylpyrrolidone of 1%, the microcrystalline Cellulose of 5%, the xylitol of 0.02%, the aminoacids complex of 0.3%, the compound vitamin mix homogeneously of 0.08%, after direct weighting is compressed into larger tablet, be ground into granule again, pack, make granule.
Embodiment 2:
For a Chinese medicine nursing compositions for postpartum recovery, raw material and weight portion thereof are: to leaf Oleum Sesami root 48 parts, Radix Gynurae bicoloris 42.5 parts, Xinjiang winged euonymus 40 parts, Herba leonuri pseudoma cranthi 37 parts, Ochotonathibetana Milne-Edwards 34 parts, hide Radix Notoginseng 32 parts, Radix Loropetali 30.5 parts, two decomposite leaf Herba Potentillae Chinensis 28 parts, Medulla caprae seu ovis 26.5 parts, mountain bean 25 parts, Radix Euonymi myrianthi 23 parts, Rubiayunnanensis (Franch.) Dlels 21.5 parts, Radix Ginkgo 19 parts, alpine yarrow 16.5 parts, lamp-stand dish 14 parts, Herba Stellariae Neglectae 10 parts, potato 7 parts of enriching blood.
Preparation method is:
(1) take leaf oil Radix Cannabis, Radix Gynurae bicoloris, Ochotonathibetana Milne-Edwards, Radix Loropetali, mountain bean, Bletilla striata (Thunb.ex A.Murray)Rchb.f. fruit by described proportioning, remove impurity, becomes coarse powder with pulverizer powder after drying, cold water soaks 40 minutes, add water and do not have medicated powder 4cm, change slow fire boiling after very hot oven boils 2.5 hours, extract; Add water and do not have medicinal residues 2.5cm, very hot oven boils, and turns slow fire boiling 25 minutes, extracts; Merge extractive liquid, adds 1.5 times of ethanol, mix homogeneously, and placement is spent the night, and makes it precipitate filter, get supernatant, cleaned by a small amount of 55% ethanol of precipitate, washing liquid and filtrate merge, decompression recycling ethanol, precipitation is completely rear filters, and filtrate is concentrated into the thick extractum of relative density 1.325 at 40 DEG C, for subsequent use;
(2) take Xinjiang winged euonymus by described proportioning, hide Radix Notoginseng, add the yellow wine sealing that alcohol content is 20%, soak at room temperature extracts 2 times, each soak time is one week, make effective ingredient fully leach hypsokinesis and get supernatant, filter, it is the extractum of 1.09 that normal pressure concentrates 16 hours obtained relative concentrations, for subsequent use;
(3) Herba leonuri pseudoma cranthi, two decomposite leaf Herba Potentillae Chinensis, Medulla caprae seu ovis, Radix Euonymi myrianthi, the western regions of the Yunnan Province grass, lamp-stand dish, potato of enriching blood is taken by described proportioning, wash clean, 30 minutes are decocted with the first very hot oven of soak by water, change slow fire again 50 minutes, extract 3 times, filter, merging filtrate, adopt spray drying technology to make extract powder filtrate, 140 orders sieve for subsequent use;
(4) take alpine yarrow and Herba Stellariae Neglectae fresh goods by described proportioning, wash clean, smashes juice, leaches impurity, and add 2-3 times of cold water, heated and boiled, slow fire is endured to paste, for subsequent use;
(5) by extractum obtained for step (1), the extractum that step (2) is obtained, the thick paste that the fine powder that step (3) obtains obtains with step (4) is mixed homogeneously, obtain mixture, cold drying, prepare the technological requirement of granule and adjuvant requirement by pharmacy routine and add lactose relative to described mixture weight 5%, the polyvinylpyrrolidone of 1%, the microcrystalline Cellulose of 5%, the xylitol of 0.02%, the aminoacids complex of 0.3%, the compound vitamin mix homogeneously of 0.08%, after direct weighting is compressed into larger tablet, be ground into granule again, pack, make granule.
Embodiment 3:
For a Chinese medicine nursing compositions for postpartum recovery, raw material and weight portion thereof are: to leaf Oleum Sesami root 56 parts, Radix Gynurae bicoloris 50 parts, Xinjiang winged euonymus 48 parts, Herba leonuri pseudoma cranthi 44 parts, Ochotonathibetana Milne-Edwards 40 parts, hide Radix Notoginseng 38 parts, Radix Loropetali 36 parts, two decomposite leaf Herba Potentillae Chinensis 34 parts, Medulla caprae seu ovis 33 parts, mountain bean 32 parts, Radix Euonymi myrianthi 30 parts, Rubiayunnanensis (Franch.) Dlels 28 parts, Radix Ginkgo 26 parts, alpine yarrow 23 parts, lamp-stand dish 20 parts, Herba Stellariae Neglectae 14 parts, potato 10 parts of enriching blood.
Preparation method is:
(1) take leaf oil Radix Cannabis, Radix Gynurae bicoloris, Ochotonathibetana Milne-Edwards, Radix Loropetali, mountain bean, Bletilla striata (Thunb.ex A.Murray)Rchb.f. fruit by described proportioning, remove impurity, becomes coarse powder with pulverizer powder after drying, cold water soaks 50 minutes, add water and do not have medicated powder 4cm, change slow fire boiling after very hot oven boils 3 hours, extract; Add water and do not have medicinal residues 2.5cm, very hot oven boils, and turns slow fire boiling 30 minutes, extracts; Merge extractive liquid, adds 2 times of ethanol, mix homogeneously, and placement is spent the night, and makes it precipitate filter, get supernatant, cleaned by a small amount of 60% ethanol of precipitate, washing liquid and filtrate merge, decompression recycling ethanol, precipitation is completely rear filters, and filtrate is concentrated into the thick extractum of relative density 1.35 at 40 DEG C, for subsequent use;
(2) take Xinjiang winged euonymus by described proportioning, hide Radix Notoginseng, add the yellow wine sealing that alcohol content is 20%, soak at room temperature extracts 3 times, each soak time is one week, make effective ingredient fully leach hypsokinesis and get supernatant, filter, it is the extractum of 1.22 that normal pressure concentrates 16 hours obtained relative concentrations, for subsequent use;
(3) Herba leonuri pseudoma cranthi, two decomposite leaf Herba Potentillae Chinensis, Medulla caprae seu ovis, Radix Euonymi myrianthi, the western regions of the Yunnan Province grass, lamp-stand dish, potato of enriching blood is taken by described proportioning, wash clean, 30 minutes are decocted with the first very hot oven of soak by water, change slow fire again 50 minutes, extract 3 times, filter, merging filtrate, adopt spray drying technology to make extract powder filtrate, 140 orders sieve for subsequent use;
(4) take alpine yarrow and Herba Stellariae Neglectae fresh goods by described proportioning, wash clean, smashes juice, leaches impurity, and add 2-3 times of cold water, heated and boiled, slow fire is endured to paste, for subsequent use;
(5) by extractum obtained for step (1), the extractum that step (2) is obtained, the thick paste that the fine powder that step (3) obtains is obtained with step (4) and described adjuvant are mixed homogeneously, obtain mixture, prepare the technological requirement of pill and adjuvant requirement by pharmacy routine and add lactose relative to described mixture weight 3%, the polyvinylpyrrolidone of 8%, the microcrystalline Cellulose of 5%, the xylitol of 0.01%, the aminoacids complex of 0.2%, the compound vitamin of 0.2%, the glycerol mix homogeneously of 20%, certain hour placed by the dough sample soft material got togather, pill made by craft or pill plate, dry, encapsulation, make pill.
Clinical trial:
1. clinical case is selected
Choice criteria: select hospital childbirth patient 120 example, stochastic averagina is divided into three groups, and the physical data such as the age of three groups of patients, pregnant week, neonatal weight are without significant difference.
2. test method:
First group of medicine prepared by the embodiment of the present invention 1, oral, every day three times, each 1 bag, electuary takes after meal; 5 days courses for the treatment of, be used in conjunction 3 courses for the treatment of;
To the medicine that second group is prepared by the embodiment of the present invention 2, oral, every day three times, each 1 bag, electuary takes after meal; 3 days courses for the treatment of, be used in conjunction 3 courses for the treatment of;
To the medicine that the 3rd group is prepared by the embodiment of the present invention 3, oral, every day three times, each 1 bag, warm water takes after meal; 2 days courses for the treatment of, be used in conjunction 3 courses for the treatment of;
3. criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect
(1) fully recover: the symptoms such as stomachache, hemorrhage, inappetence all disappear, and puerpera's physical recovery is normal;
(2) effective: the symptoms such as stomachache, hemorrhage, inappetence alleviate to some extent, and puerpera's health takes a turn for the better to some extent;
(3) invalid: the symptoms such as stomachache, hemorrhage, inappetence are without alleviating or increasing the weight of.
3.2 treatment statistical results
Three groups of data merge statistics, recovery from illness: 97 examples, effectively: 19 examples, invalid: 4 examples.
4. conclusion: in clinical trial process, the patient accepting Drug therapy of the present invention finds no any untoward reaction, and the puerperal abdonimal pain in various degree that patient occurs, hemorrhage etc. mostly can be fully recovered.From data, medicine of the present invention is evident in efficacy to postpartum recovery, and rehabilitation rate reaches more than 96.7%, has good effect to puerpera's physical rehabilitation in puerperal and maintenance.
5. clinical individual case
Case 1: Lee, 24 years old.Puerperal abdominal pain, hemorrhage more, health extremely feeble, can not walk, and after taking a course for the treatment of, stomachache alleviates, stopped bleeding, can walk voluntarily, and after continuing to take 2 courses for the treatment of, physical recovery is normal.
Case 2: grandson so-and-so, female, 32 years old.Puerperal fever, suffer from abdominal pain, have hemorrhage on a small quantity, take other drug and do not take a turn for the better, lochia non-stop, after taking a course for the treatment of of medicine of the present invention by doctor formula, heating stops, and stomachache disappears, and lochia reduces, free from extraneous odour, after continuing to take two courses for the treatment of, and transference cure.
Case 3: high mountain, 27 years old.Natural labor postabdomen pain, hemorrhage, spirit is weak, and without appetite, illustratively persuade with after the course for the treatment of of medicine of the present invention, stomachache alleviates, stopped bleeding, and spirit takes a turn for the better, and appetite normally, and after continuing to take 2 courses for the treatment of, physical recovery is normal.
Last it is noted that above embodiment is only in order to illustrate technical scheme of the present invention, be not intended to limit; Although with reference to previous embodiment to invention has been detailed description, those of ordinary skill in the art is to be understood that: it still can be modified to the technical scheme described in previous embodiment, or carries out equivalent replacement to wherein portion of techniques feature; And these amendments or replacement, do not make the essence of appropriate technical solution depart from the spirit and scope of embodiment of the present invention technical scheme.
Claims (7)
1. the Chinese medicine nursing compositions for postpartum recovery, it is characterized in that, raw material and weight portion thereof are: to leaf Oleum Sesami root 40-56 part, Radix Gynurae bicoloris 35-50 part, Xinjiang winged euonymus 32-48 part, Herba leonuri pseudoma cranthi 30-44 part, Ochotonathibetana Milne-Edwards 28-40 part, hide Radix Notoginseng 26-38 part, Radix Loropetali 25-36 part, two decomposite leaf Herba Potentillae Chinensis 22-34 parts, Medulla caprae seu ovis 20-33 part, mountain bean 18-32 part, Radix Euonymi myrianthi 16-30 part, Rubiayunnanensis (Franch.) Dlels 15-28 part, Radix Ginkgo 12-26 part, alpine yarrow 10-23 part, lamp-stand dish 8-20 part, Herba Stellariae Neglectae 6-14 part, potato 4-10 part of enriching blood.
2. the Chinese medicine nursing compositions for postpartum recovery, it is characterized in that, raw material and weight portion thereof are: to leaf Oleum Sesami root 48 parts, Radix Gynurae bicoloris 42.5 parts, Xinjiang winged euonymus 40 parts, Herba leonuri pseudoma cranthi 37 parts, Ochotonathibetana Milne-Edwards 34 parts, hide Radix Notoginseng 32 parts, Radix Loropetali 30.5 parts, two decomposite leaf Herba Potentillae Chinensis 28 parts, Medulla caprae seu ovis 26.5 parts, mountain bean 25 parts, Radix Euonymi myrianthi 23 parts, Rubiayunnanensis (Franch.) Dlels 21.5 parts, Radix Ginkgo 19 parts, alpine yarrow 16.5 parts, lamp-stand dish 14 parts, Herba Stellariae Neglectae 10 parts, potato 7 parts of enriching blood.
3. a kind of Chinese medicine nursing compositions for postpartum recovery as claimed in claim 1 or 2, is characterized in that described Xinjiang winged euonymus and hides Radix Notoginseng needing infusing drugs in wine to extract.
4. the preparation method of a kind of Chinese medicine nursing compositions for postpartum recovery as described in claims 1 to 3, is characterized in that comprising the following steps:
(1) take leaf oil Radix Cannabis, Radix Gynurae bicoloris, Ochotonathibetana Milne-Edwards, Radix Loropetali, mountain bean, Bletilla striata (Thunb.ex A.Murray)Rchb.f. fruit by described proportioning, remove impurity, becomes coarse powder with pulverizer powder after drying, cold water soaks 30-50 minute, add water and do not have medicated powder 4cm, after very hot oven boils, change slow fire boiling 2-3 hour, extract; Add water and do not have medicinal residues 2.5cm, very hot oven boils, and turns slow fire boiling 20-30 minute, extracts; Merge extractive liquid, adds 1-2 times of ethanol, mix homogeneously, placement is spent the night, and makes it precipitate filter, gets supernatant, the a small amount of 50%-60% ethanol of precipitate is cleaned, washing liquid and filtrate merge, decompression recycling ethanol, and precipitation is completely rear filters, filtrate is concentrated into the thick extractum of relative density 1.30-1.35 at 40 DEG C, for subsequent use;
(2) take Xinjiang winged euonymus by described proportioning, hide Radix Notoginseng, add the yellow wine sealing that alcohol content is 20%, soak at room temperature extracts 2-3 time, each soak time is one week, make effective ingredient fully leach hypsokinesis and get supernatant, filter, it is the extractum of 0.96-1.22 that normal pressure concentrates 16 hours obtained relative concentrations, for subsequent use;
(3) Herba leonuri pseudoma cranthi, two decomposite leaf Herba Potentillae Chinensis, Medulla caprae seu ovis, Radix Euonymi myrianthi, the western regions of the Yunnan Province grass, lamp-stand dish, potato of enriching blood is taken by described proportioning, wash clean, 30 minutes are decocted with the first very hot oven of soak by water, change slow fire again 50 minutes, extract 3 times, filter, merging filtrate, adopt spray drying technology to make extract powder filtrate, 140 orders sieve for subsequent use;
(4) take alpine yarrow and Herba Stellariae Neglectae fresh goods by described proportioning, wash clean, smashes juice, leaches impurity, and add 2-3 times of cold water, heated and boiled, slow fire is endured to paste, for subsequent use;
(5) fine powder that extractum extractum obtained for step (1), step (2) obtained, step (3) obtain is mixed homogeneously with the thick paste that step (4) obtains, and obtains the Chinese medicine nursing composite preparation of the present invention for postpartum recovery.
5. the preparation method of a kind of Chinese medicine nursing compositions for postpartum recovery as claimed in claim 4, is characterized in that described medicine is added pharmacy customary adjuvant makes granule or pill.
6. the preparation method of a kind of Chinese medicine nursing compositions for postpartum recovery as claimed in claim 4, is characterized in that the preparation method of described granule is:
(1) take leaf oil Radix Cannabis, Radix Gynurae bicoloris, Ochotonathibetana Milne-Edwards, Radix Loropetali, mountain bean, Bletilla striata (Thunb.ex A.Murray)Rchb.f. fruit by described proportioning, remove impurity, becomes coarse powder with pulverizer powder after drying, cold water soaks 30-50 minute, add water and do not have medicated powder 4cm, after very hot oven boils, change slow fire boiling 2-3 hour, extract; Add water and do not have medicinal residues 2.5cm, very hot oven boils, and turns slow fire boiling 20-30 minute, extracts; Merge extractive liquid, adds 1-2 times of ethanol, mix homogeneously, placement is spent the night, and makes it precipitate filter, gets supernatant, the a small amount of 50%-60% ethanol of precipitate is cleaned, washing liquid and filtrate merge, decompression recycling ethanol, and precipitation is completely rear filters, filtrate is concentrated into the thick extractum of relative density 1.30-1.35 at 40 DEG C, for subsequent use;
(2) take Xinjiang winged euonymus by described proportioning, hide Radix Notoginseng, add the yellow wine sealing that alcohol content is 20%, soak at room temperature extracts 2-3 time, each soak time is one week, make effective ingredient fully leach hypsokinesis and get supernatant, filter, it is the extractum of 0.96-1.22 that normal pressure concentrates 16 hours obtained relative concentrations, for subsequent use;
(3) Herba leonuri pseudoma cranthi, two decomposite leaf Herba Potentillae Chinensis, Medulla caprae seu ovis, Radix Euonymi myrianthi, the western regions of the Yunnan Province grass, lamp-stand dish, potato of enriching blood is taken by described proportioning, wash clean, 30 minutes are decocted with the first very hot oven of soak by water, change slow fire again 50 minutes, extract 3 times, filter, merging filtrate, adopt spray drying technology to make extract powder filtrate, 140 orders sieve for subsequent use;
(4) take alpine yarrow and Herba Stellariae Neglectae fresh goods by described proportioning, wash clean, smashes juice, leaches impurity, and add 2-3 times of cold water, heated and boiled, slow fire is endured to paste, for subsequent use;
(5) by extractum obtained for step (1), the extractum that step (2) is obtained, the thick paste that the fine powder that step (3) obtains is obtained with step (4) and described adjuvant are mixed homogeneously, obtain mixture, cold drying, prepare the technological requirement of granule and adjuvant requirement by pharmacy routine and add lactose relative to described mixture weight 5%, the polyvinylpyrrolidone of 1%, the microcrystalline Cellulose of 5%, the xylitol of 0.02%, the aminoacids complex of 0.3%, the compound vitamin mix homogeneously of 0.08%, after direct weighting is compressed into larger tablet, be ground into granule again, pack, obtain granule.
7. the preparation method of a kind of Chinese medicine nursing compositions for postpartum recovery as claimed in claim 4, is characterized in that the preparation method of described pill is:
(1) take leaf oil Radix Cannabis, Radix Gynurae bicoloris, Ochotonathibetana Milne-Edwards, Radix Loropetali, mountain bean, Bletilla striata (Thunb.ex A.Murray)Rchb.f. fruit by described proportioning, remove impurity, becomes coarse powder with pulverizer powder after drying, cold water soaks 30-50 minute, add water and do not have medicated powder 4cm, after very hot oven boils, change slow fire boiling 2-3 hour, extract; Add water and do not have medicinal residues 2.5cm, very hot oven boils, and turns slow fire boiling 20-30 minute, extracts; Merge extractive liquid, adds 1-2 times of ethanol, mix homogeneously, placement is spent the night, and makes it precipitate filter, gets supernatant, the a small amount of 50%-60% ethanol of precipitate is cleaned, washing liquid and filtrate merge, decompression recycling ethanol, and precipitation is completely rear filters, filtrate is concentrated into the thick extractum of relative density 1.30-1.35 at 40 DEG C, for subsequent use;
(2) take Xinjiang winged euonymus by described proportioning, hide Radix Notoginseng, add the yellow wine sealing that alcohol content is 20%, soak at room temperature extracts 2-3 time, each soak time is one week, make effective ingredient fully leach hypsokinesis and get supernatant, filter, it is the extractum of 0.96-1.22 that normal pressure concentrates 16 hours obtained relative concentrations, for subsequent use;
(3) Herba leonuri pseudoma cranthi, two decomposite leaf Herba Potentillae Chinensis, Medulla caprae seu ovis, Radix Euonymi myrianthi, the western regions of the Yunnan Province grass, lamp-stand dish, potato of enriching blood is taken by described proportioning, wash clean, 30 minutes are decocted with the first very hot oven of soak by water, change slow fire again 50 minutes, extract 3 times, filter, merging filtrate, adopt spray drying technology to make extract powder filtrate, 140 orders sieve for subsequent use;
(4) take alpine yarrow and Herba Stellariae Neglectae fresh goods by described proportioning, wash clean, smashes juice, leaches impurity, and add 2-3 times of cold water, heated and boiled, slow fire is endured to paste, for subsequent use;
(5) by extractum obtained for step (1), the extractum that step (2) is obtained, the thick paste that the fine powder that step (3) obtains is obtained with step (4) and described adjuvant are mixed homogeneously, obtain mixture, prepare the technological requirement of pill and adjuvant requirement by pharmacy routine and add lactose relative to described mixture weight 3%, the polyvinylpyrrolidone of 8%, the microcrystalline Cellulose of 5%, the xylitol of 0.01%, the aminoacids complex of 0.2%, the compound vitamin of 0.2%, the glycerol mix homogeneously of 20%, certain hour placed by the dough sample soft material got togather, pill made by craft or pill plate, dry, encapsulation, obtain pill.
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Cited By (2)
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CN109156735A (en) * | 2018-08-02 | 2019-01-08 | 佛山科学技术学院 | A kind of edible rice flour facilitating pregnant woman's postoperative rehabilitation |
CN109731061A (en) * | 2019-03-22 | 2019-05-10 | 赵学梅 | A kind of nursing Chinese medicine composition for postpartum recovery |
-
2015
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Title |
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戴德银等: "《新编简明中成药手册》", 31 December 2014, 人民军医出版社 * |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109156735A (en) * | 2018-08-02 | 2019-01-08 | 佛山科学技术学院 | A kind of edible rice flour facilitating pregnant woman's postoperative rehabilitation |
CN109731061A (en) * | 2019-03-22 | 2019-05-10 | 赵学梅 | A kind of nursing Chinese medicine composition for postpartum recovery |
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