CN105311514A - External-use Miao medicine liniment for treating bone diseases - Google Patents
External-use Miao medicine liniment for treating bone diseases Download PDFInfo
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- CN105311514A CN105311514A CN201510844718.3A CN201510844718A CN105311514A CN 105311514 A CN105311514 A CN 105311514A CN 201510844718 A CN201510844718 A CN 201510844718A CN 105311514 A CN105311514 A CN 105311514A
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Abstract
The invention relates to external-use Miao medicine liniment for treating bone diseases. The external-use Miao medicine liniment is prepared from herba chloranthi serrate, cynomorium songaricum, roots of laportea bulbifera, dysosma versipellis, drooping stringbush flower roots and bark, lespedeza cuneata, roots of Chinese barberries, as arum, lycopodium clavatum, pawpaws, alangium platanifolium, artemisia rupestris, toddalia asiatua lam, olibanum, myrrh, crude sichuan aconite roots, raw kusnezoff monkshood roots, garden balsam stem, large-leaved gentian, ground beeltle, nux vomica, berba aristolochiae mollissimae, rhizoma drynariae, radix clematidis, fructus kochiae, fructus cnidii, pepper, sophora flavescens, cortex phellodendri, safflower, radix stemonae, borneol, camphor and asiatic toddalia roots. The traditional Chinese medicine composition can treat rheumatism rheumatoid arthritis, scapulohumeral periarthritis, cervical spondylosis, cervical hyperplasia, lumbar spondylosis, lumbar disc herniation, spur, osteoproliferation, sciatica, parturient paresis of women, numbness of limbs, cool and cold hands and feet, joint ankylosis, lumbar muscle degeneration, long-term denervation and other arthralgia, various kinds of stubborn dermatitis, neurodermatitis and the like.
Description
Technical field
The present invention relates to field of medicaments, relate in particular to a kind of external Miao medicine liniment for the treatment of osteopathia.
Background technology
The blood circulation that rheumatic osteopathia mainly causes due to wind and cold is obstructed, causes the bad disease caused of nutrition supply comprising flesh, ligament, synovial bursa, fascia.Arthropathy is outer still with swelling and moving obstacle apart from pain, in outbreak with alleviate the chronic course of disease alternately, some patients and can occur disabling and viscera function exhaustion in joint.Rheumatic osteopathia is the chronic systemic disease that touching difficulty heals, especially with between twenty and fifty sickness rate higher (patient age of 80% was at 20 years old-45 years old): 1, during onset, onset is slow, patient before this in several weeks to the lassitude and weak of some months, to lose weight, the prodrome such as anorexia, low grade fever and numb hand and foot twinge.2, there is arthralgia subsequently, stiff, enlargement surrounding skin is warm, flushing automatically and passive exercise all cause pain.Start one, two joint involvement, migrans often.3, develop into symmetry polyarthritis later from the Minor articulus of distal limbs, involve other joint again.Secondly for the palm refer to, toe, wrist, knee joint, elbow, ankle, shoulder and hip joint etc., daystart ankylosis, muscular soreness.4, along with the development of rheumatism, rheumatoid arthritis pathological changes, the irregular heating of patient, pulse is accelerated, remarkable anemia, and joint becomes stiff and lopsided, causes maimed person.Knee joint, elbow, finger, wrist become fixing and bend position, and finger becomes subluxation laterally, and patient loses self care ability, all day not from bedding, is unable to stir any more and angor.
Summary of the invention
The object of this invention is to provide a kind of external Miao medicine liniment for the treatment of osteopathia.
In order to realize object of the present invention, the invention provides a kind of external Miao medicine liniment for the treatment of osteopathia, it comprises the material of following weight portion: Herba Chloranthi Henryi (Herba Choranthi seu Lysimachiae) 10-20 part, Herba Cynomorii 30-50 part, largespike woodnettle root 50-100 part, Radix et Rhizoma Dysosmatis 10-15 part, Flos Wikstroemiae Nutantis 10-15 part, old tendon Bovis seu Bubali 10-15 part, Radix Berberidis 10-15 part, four liang of numb 5-10 parts, Herba Lycopodii 10-15 part, Fructus Chaenomelis 10-15 part, Radix Alangii 12-15 part, Herba Achilleae 5-10 part, Sedum aizoon L. 10-15 part, Olibanum 10-15 part, Myrrha 10-20 part, Radix Aconiti 5-10 part, Radix Aconiti Kusnezoffii 5-10 part, Herba speranskiae tuberculatae 10-20 part, Radix Gentianae Macrophyllae 10-20 part, Eupolyphaga Seu Steleophaga 10-15 part, Semen Strychni 5-10 part, Herba Aristolochiae Mollissimae 10-20 part, Rhizoma Drynariae 10-20 part, Radix Clematidis 10-20 part, Fructus Kochiae 10-20 part, Fructus Cnidii 10-20 part, Pericarpium Zanthoxyli 15-30 part, Radix Sophorae Flavescentis 10-15 part, Cortex Phellodendri 10-15 part, Flos Carthami 5-12 part, Radix Stemonae 10-12 part, Borneolum Syntheticum 5-8 part, Camphora 20-30 part and Radix Toddaliae Asiaticae 20-30 part.
Preferably, the external Miao medicine liniment for the treatment of osteopathia of the present invention comprises the material of following weight portion: Herba Chloranthi Henryi (Herba Choranthi seu Lysimachiae) 15 parts, Herba Cynomorii 40 parts, largespike woodnettle root 80 parts, Radix et Rhizoma Dysosmatis 12 parts, Flos Wikstroemiae Nutantis 12 parts, old tendon Bovis seu Bubali 12 parts, Radix Berberidis 12 parts, four liang of fiber crops 8 parts, Herba Lycopodii 12 parts, Fructus Chaenomelis 12 parts, Radix Alangii 13 parts, Herba Achilleae 7 parts, Sedum aizoon L. 12 parts, Olibanum 12 parts, Myrrha 15 parts, Radix Aconiti 7 parts, Radix Aconiti Kusnezoffii 7 parts, Herba speranskiae tuberculatae 15 parts, Radix Gentianae Macrophyllae 15 parts, Eupolyphaga Seu Steleophaga 12 parts, Semen Strychni 8 parts, Herba Aristolochiae Mollissimae 15 parts, Rhizoma Drynariae 15 parts, Radix Clematidis 15 parts, the Fructus Kochiae 15 parts, Fructus Cnidii 15 parts, 20 parts, Pericarpium Zanthoxyli, Radix Sophorae Flavescentis 12 parts, Cortex Phellodendri 12 parts, 10 parts, Flos Carthami, the Radix Stemonae 11 parts, Borneolum Syntheticum 7 parts, Camphora 25 parts and Radix Toddaliae Asiaticae 25 parts.
More preferably, the external Miao medicine liniment for the treatment of osteopathia of the present invention also comprises the material of following weight portion: 5-(4-the ethoxyl phenenyl)-2H-pyran-2-one of 3 parts.
The present invention also provides the purposes of 5-(4-ethoxyl phenenyl)-2H-pyran-2-one in the medicine of preparation treatment osteopathia.
Preferably, described medicine can be tablet, dispersible tablet, capsule, pill or decoction.
Traditional Chinese medicine composition for treating rheumatism atrophic arthritis of the present invention, scapulohumeral periarthritis, cervical spondylosis, hyperosteogeny, lumbar spondylosis, prolapse of lumbar intervertebral disc, bony spur, hyperosteogeny, sciatica, woman puerperal fever, numb limbs and tense tendons, brothers are cold and cool, arthromyodynia, various stubborn dermatitis and the neurodermatitis etc. such as joint stiffness, lumbar muscle strain, outmoded injury.
Detailed description of the invention
The present invention is further illustrated below by embodiment.It should be understood that embodiments of the invention are for illustration of the present invention instead of limitation of the present invention.Essence according to the present invention all belongs to the scope of protection of present invention to the simple modifications that the present invention carries out.Unless otherwise stated, the percent in the present invention is percetage by weight.
Embodiment
Take Herba Chloranthi Henryi (Herba Choranthi seu Lysimachiae) 15 grams, Herba Cynomorii 40 grams, largespike woodnettle root 80 grams, Radix et Rhizoma Dysosmatis 12 grams, Flos Wikstroemiae Nutantis 12 grams, old tendon Bovis seu Bubali 12 grams, Radix Berberidis 12 grams, four liang of fiber crops 8 grams, Herba Lycopodii 12 grams, Fructus Chaenomelis 12 grams, Radix Alangii 13 grams, Herba Achilleae 7 grams, Sedum aizoon L. 12 grams, Olibanum 12 grams, Myrrha 15 grams, Radix Aconiti 7 grams, Radix Aconiti Kusnezoffii 7 grams, Herba speranskiae tuberculatae 15 grams, Radix Gentianae Macrophyllae 15 grams, Eupolyphaga Seu Steleophaga 12 grams, Semen Strychni 8 grams, Herba Aristolochiae Mollissimae 15 grams, Rhizoma Drynariae 15 grams, Radix Clematidis 15 grams, the Fructus Kochiae 15 grams, Fructus Cnidii 15 grams, 20 grams, Pericarpium Zanthoxyli, Radix Sophorae Flavescentis 12 grams, Cortex Phellodendri 12 grams, 10 grams, Flos Carthami, the Radix Stemonae 11 grams, Borneolum Syntheticum 7 grams, Camphora 25 grams and Radix Toddaliae Asiaticae 25 grams, pulverize, cross 100 mesh sieves, mix homogeneously obtains powder.
Experimental example
Osteoarthritis is the coefficient result of mechanics and biological factor, thinks that IgG2 α raises at present relevant with the order of severity of the course of disease and disease.
Knee osteoarthritis model and administration
By cleaning grade (SPF) male Wistar rat (Mus 5-6 in the age month, weight 170.0 ± 20.5) be divided into 6 groups: Normal group (Normalcontrolgroup, NC), model control group (Modelcontrolgroup, MC), glucosamine matched group (Glucosaminecontrolgroup, GS), administration group 1, administration group 2, administration group 3.Often organize 10.Except Normal group, respectively organize the Cys aqueous solution of right knee joint injection 4 % by weight Papain enzyme aqueous solution 10 μ L and 0.03mol/L of rat to all the other, and strengthened respectively at the 3rd, 7 day, cause osteoarthritis.After modeling the 14th day starts administration, and each group dosage is as follows: normal group and model group, give normal saline gavage 1mL/100g body weight; Glucosamine group, glucosamine 1g adds 100mL normal saline and becomes suspension, gives gavage 1mL/100g body weight; Administration group 1, the powder 5g of embodiment adds 100mL normal saline and becomes suspension, gives gavage 1mL/100g body weight; 5-(4-the ethoxyl phenenyl)-2H-pyran-2-one of administration group 2,0.02g adds 100mL normal saline and becomes suspension, gives gavage 1mL/100g body weight; Administration group 3,5-(4-the ethoxyl phenenyl)-2H-pyran-2-one of powder 2.5g with 0.01g of embodiment adds 100mL normal saline and becomes suspension, gives gavage 1mL/100g body weight.1 times/day, successive administration 30d, draws materials for after modeling the 49th day.
ELISA method detects IgG2 α
The 49th day by sacrifice of animal after, row ventral aorta take a blood sample, by the centrifugal 5min of institute blood sampling 3000r/min, get serum, put-80 DEG C of Refrigerator stores to be measured.Concrete operation step is undertaken by test kit (IgG2 α ELISA kit is purchased from Mei Lian bio tech ltd, Shanghai) description.The results are shown in following table.
| Group | IgG2α(μg·mL -1) |
| Normal group | 40.36±5.29 |
| Model group | 59.62±7.18 |
| Glucosamine group | 52.71±6.06 |
| Administration group 1 | 49.63±6.37 |
| Administration group 2 | 41.08±5.52 |
| Administration group 3 | 46.52±6.69 |
Claims (5)
1. treat the external Miao medicine liniment of osteopathia for one kind, it is characterized in that, it comprises the material of following weight portion: Herba Chloranthi Henryi (Herba Choranthi seu Lysimachiae) 10-20 part, Herba Cynomorii 30-50 part, largespike woodnettle root 50-100 part, Radix et Rhizoma Dysosmatis 10-15 part, Flos Wikstroemiae Nutantis 10-15 part, old tendon Bovis seu Bubali 10-15 part, Radix Berberidis 10-15 part, four liang of numb 5-10 parts, Herba Lycopodii 10-15 part, Fructus Chaenomelis 10-15 part, Radix Alangii 12-15 part, Herba Achilleae 5-10 part, Sedum aizoon L. 10-15 part, Olibanum 10-15 part, Myrrha 10-20 part, Radix Aconiti 5-10 part, Radix Aconiti Kusnezoffii 5-10 part, Herba speranskiae tuberculatae 10-20 part, Radix Gentianae Macrophyllae 10-20 part, Eupolyphaga Seu Steleophaga 10-15 part, Semen Strychni 5-10 part, Herba Aristolochiae Mollissimae 10-20 part, Rhizoma Drynariae 10-20 part, Radix Clematidis 10-20 part, Fructus Kochiae 10-20 part, Fructus Cnidii 10-20 part, Pericarpium Zanthoxyli 15-30 part, Radix Sophorae Flavescentis 10-15 part, Cortex Phellodendri 10-15 part, Flos Carthami 5-12 part, Radix Stemonae 10-12 part, Borneolum Syntheticum 5-8 part, Camphora 20-30 part and Radix Toddaliae Asiaticae 20-30 part.
2. the external Miao medicine liniment for the treatment of osteopathia according to claim 1, it is characterized in that, it comprises the material of following weight portion: Herba Chloranthi Henryi (Herba Choranthi seu Lysimachiae) 15 parts, Herba Cynomorii 40 parts, largespike woodnettle root 80 parts, Radix et Rhizoma Dysosmatis 12 parts, Flos Wikstroemiae Nutantis 12 parts, old tendon Bovis seu Bubali 12 parts, Radix Berberidis 12 parts, four liang of fiber crops 8 parts, Herba Lycopodii 12 parts, Fructus Chaenomelis 12 parts, Radix Alangii 13 parts, Herba Achilleae 7 parts, Sedum aizoon L. 12 parts, Olibanum 12 parts, Myrrha 15 parts, Radix Aconiti 7 parts, Radix Aconiti Kusnezoffii 7 parts, Herba speranskiae tuberculatae 15 parts, Radix Gentianae Macrophyllae 15 parts, Eupolyphaga Seu Steleophaga 12 parts, Semen Strychni 8 parts, Herba Aristolochiae Mollissimae 15 parts, Rhizoma Drynariae 15 parts, Radix Clematidis 15 parts, the Fructus Kochiae 15 parts, Fructus Cnidii 15 parts, 20 parts, Pericarpium Zanthoxyli, Radix Sophorae Flavescentis 12 parts, Cortex Phellodendri 12 parts, 10 parts, Flos Carthami, the Radix Stemonae 11 parts, Borneolum Syntheticum 7 parts, Camphora 25 parts and Radix Toddaliae Asiaticae 25 parts.
3. the external Miao medicine liniment for the treatment of osteopathia according to claim 1 and 2, is characterized in that, it also comprises the material of following weight portion: 5-(4-the ethoxyl phenenyl)-2H-pyran-2-one of 3 parts.
The purposes of 4.5-(4-ethoxyl phenenyl)-2H-pyran-2-one in the medicine of preparation treatment osteopathia.
5. purposes according to claim 4, is characterized in that, described medicine can be tablet, dispersible tablet, capsule, pill or decoction.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201510844718.3A CN105311514A (en) | 2015-11-29 | 2015-11-29 | External-use Miao medicine liniment for treating bone diseases |
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| CN201510844718.3A CN105311514A (en) | 2015-11-29 | 2015-11-29 | External-use Miao medicine liniment for treating bone diseases |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106177356A (en) * | 2016-08-18 | 2016-12-07 | 贵州盛世保康茶开发有限公司 | Quick acting bone knitting Miao Ethnomedicine |
| CN106421690A (en) * | 2016-09-19 | 2017-02-22 | 杨佩义 | External drug formula for eliminating ostealgia |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1966018A (en) * | 2006-10-25 | 2007-05-23 | 雒宏志 | Chinese medicinal formulation for treating rheumatic and rheumatoid disease |
| CN101049387A (en) * | 2007-05-16 | 2007-10-10 | 陈昌虎 | Composition of Chinese traditional medicine for treating rheumatic bone disease |
| CN102755537A (en) * | 2012-06-28 | 2012-10-31 | 李伟 | External Chinese patent medicine for treating lumbocrural pains and application of external Chinese patent medicine |
| CN103316308A (en) * | 2012-03-20 | 2013-09-25 | 于文波 | Traditional Chinese medical liquor for external use |
| CN103933143A (en) * | 2014-05-06 | 2014-07-23 | 高凤美 | External-use traditional Chinese medicine for treating rheumatoid arthritis |
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2015
- 2015-11-29 CN CN201510844718.3A patent/CN105311514A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1966018A (en) * | 2006-10-25 | 2007-05-23 | 雒宏志 | Chinese medicinal formulation for treating rheumatic and rheumatoid disease |
| CN101049387A (en) * | 2007-05-16 | 2007-10-10 | 陈昌虎 | Composition of Chinese traditional medicine for treating rheumatic bone disease |
| CN103316308A (en) * | 2012-03-20 | 2013-09-25 | 于文波 | Traditional Chinese medical liquor for external use |
| CN102755537A (en) * | 2012-06-28 | 2012-10-31 | 李伟 | External Chinese patent medicine for treating lumbocrural pains and application of external Chinese patent medicine |
| CN103933143A (en) * | 2014-05-06 | 2014-07-23 | 高凤美 | External-use traditional Chinese medicine for treating rheumatoid arthritis |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106177356A (en) * | 2016-08-18 | 2016-12-07 | 贵州盛世保康茶开发有限公司 | Quick acting bone knitting Miao Ethnomedicine |
| CN106421690A (en) * | 2016-09-19 | 2017-02-22 | 杨佩义 | External drug formula for eliminating ostealgia |
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Application publication date: 20160210 |
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