CN101732470A - Medicinal composition for treating protrusion of lumbar vertebral disc and osteonecrosis of femeral head and usage thereof - Google Patents

Medicinal composition for treating protrusion of lumbar vertebral disc and osteonecrosis of femeral head and usage thereof Download PDF

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CN101732470A
CN101732470A CN200810227336A CN200810227336A CN101732470A CN 101732470 A CN101732470 A CN 101732470A CN 200810227336 A CN200810227336 A CN 200810227336A CN 200810227336 A CN200810227336 A CN 200810227336A CN 101732470 A CN101732470 A CN 101732470A
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王政平
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Abstract

The invention discloses a medicinal composition for treating protrusion of lumbar vertebral disc and osteonecrosis of femeral head and usage thereof. The medicinal composition comprises himalayan teasel root, Chinese taxillus twig, suberect spatholobus stem, incised notopterygium rhizome, doubleteeth pubescent angilica root, frankincense, myrrh and the like. The medicinal composition has a formula which adopts pure Chinese medicaments, and has obvious effects of treating the protrusion of the lumbar vertebral disc, hyperplasia of lumbar vertebra, and the osteonecrosis of the femeral head. The medicinal composition has the effects of dispelling wind and dissipating cold, freeing channels and quickening network vessels, activating blood and dissolving stasis, eliminating ulcer and relieving pain, promoting bone regeneration and improving immunity of human bodies. The medicinal composition has the advantages of obvious curative effect, high cure rate, and no toxic or side effects.

Description

A kind of pharmaceutical composition and purposes for the treatment of prolapse of lumbar intervertebral disc and femur head necrosis
Technical field
The present invention relates to a kind of pharmaceutical composition, particularly relate to a kind of pharmaceutical composition and purposes for the treatment of prolapse of lumbar intervertebral disc and femur head necrosis.
Background technology
Lumbar spondylosis motherland medical science claims lumbago and skelalgia, and the ill initial stage, the lighter produced lumbar vertebra hyperosteogeny, weight person's prolapse of lumbar intervertebral disc because wind and cold is attacked.If treat improper or abuse the Western medicine rheumatism or abuse hormone medicine.In the course of time because the wind what turns to the touching difficulty of damp and hot finding more for a long time, individual patient is joined and the necrosis of ischemic femoral head type, causes the hidden danger that is difficult to cure.Femoral head necrosis not record of medical science in ancient times, the most of femur head necrosis of clinical discovery is because prolapse of lumbar intervertebral disc or hyperosteogeny, the treatment on abuse hormone medicine and hidden danger to ischemic necrosis of femoral head, often with the one-sided bilateral that causes, CT examination is obviously found out downright bad focal zone degree of necrosis.China's Chinese Traditional Medicines also emerge in an endless stream but do not have to find real Chinese Traditional Medicines of curing at present.
The present invention can play the curative effect of healing to prolapse of lumbar intervertebral disc and femur head necrosis, and no matter which kind of the patient belongs to, even caused head necrosis, degree also can effectively be controlled.The ill initial stage can cure, and femur head necrosis substantially can be controlled the patient of 3-5, throws away crutches, and symptom is obviously improved, and in the over thousands of routine lumbar spondylosis patient of clinical treatment, curative effect reaches more than 95%.The patient has tangible pain relief or healing.
Summary of the invention
The object of the invention is to provide the pharmaceutical composition of a kind of treatment prolapse of lumbar intervertebral disc and femur head necrosis.
Another object of the present invention is to provide the purposes of this pharmaceutical composition.
The present invention is achieved through the following technical solutions:
The crude drug of pharmaceutical composition of the present invention consists of:
Radix Dipsaci 50-150 weight portion Herba Taxilli 40-120 weight portion Caulis Spatholobi 50-150 weight portion
Rhizoma Et Radix Notopterygii 30-90 weight portion Radix Angelicae Pubescentis 30-90 weight portion Olibanum 25-75 weight portion
Myrrha 25-75 weight portion Ramulus Cinnamomi 15-45 weight portion Radix Paeoniae Alba 25-75 weight portion
Radix Achyranthis Bidentatae 30-90 weight portion Cortex Eucommiae 25-75 weight portion Scorpio 15-45 weight portion
Scolopendra 7-23 weight portion Eupolyphaga Seu Steleophaga 30-90 weight portion Herba Houttuyniae 30-90 weight portion
Radix Angelicae Sinensis 25-75 weight portion Radix Glycyrrhizae 15-45 weight portion Pheretima 25-75 weight portion
Radix Stephaniae Tetrandrae 25-75 weight portion.
The crude drug composition of pharmaceutical composition of the present invention is preferably:
Radix Dipsaci 100 weight portion Herba Taxillis 80 weight portion Caulis Spatholobis 100 weight portions
Rhizoma Et Radix Notopterygii 60 weight portion Radix Angelicae Pubescentiss 60 weight portion Olibanums 50 weight portions
The Myrrha 50 weight portion Ramulus Cinnamomi 30 weight portion Radix Paeoniae Albas 50 weight portions
The Radix Achyranthis Bidentatae 60 weight portion Cortexs Eucommiae 50 weight portion Scorpios 30 weight portions
Scolopendra 15 weight portion Eupolyphaga Seu Steleophagas 60 weight portion Herba Houttuyniae 60 weight portions
Radix Angelicae Sinensis 50 weight portion Radix Glycyrrhizaes 30 weight portion Pheretimas 50 weight portions
Radix Stephaniae Tetrandrae 50 weight portions.
The crude drug composition of pharmaceutical composition of the present invention is preferably:
Radix Dipsaci 60 weight portion Herba Taxillis 110 weight portion Caulis Spatholobis 60 weight portions
Rhizoma Et Radix Notopterygii 80 weight portion Radix Angelicae Pubescentiss 40 weight portion Olibanums 65 weight portions
The Myrrha 35 weight portion Ramulus Cinnamomi 35 weight portion Radix Paeoniae Albas 35 weight portions
The Radix Achyranthis Bidentatae 80 weight portion Cortexs Eucommiae 35 weight portion Scorpios 35 weight portions
Scolopendra 10 weight portion Eupolyphaga Seu Steleophagas 80 weight portion Herba Houttuyniae 40 weight portions
Radix Angelicae Sinensis 65 weight portion Radix Glycyrrhizaes 25 weight portion Pheretimas 65 weight portions
Radix Stephaniae Tetrandrae 35 weight portions.
The crude drug composition of pharmaceutical composition of the present invention is preferably:
Radix Dipsaci 140 weight portion Herba Taxillis 50 weight portion Caulis Spatholobis 140 weight portions
Rhizoma Et Radix Notopterygii 40 weight portion Radix Angelicae Pubescentiss 80 weight portion Olibanums 35 weight portions
The Myrrha 65 weight portion Ramulus Cinnamomi 25 weight portion Radix Paeoniae Albas 65 weight portions
The Radix Achyranthis Bidentatae 40 weight portion Cortexs Eucommiae 65 weight portion Scorpios 25 weight portions
Scolopendra 20 weight portion Eupolyphaga Seu Steleophagas 40 weight portion Herba Houttuyniae 80 weight portions
Radix Angelicae Sinensis 35 weight portion Radix Glycyrrhizaes 35 weight portion Pheretimas 35 weight portions
Radix Stephaniae Tetrandrae 65 weight portions.
The preferred Radix Cyathulae of described Radix Achyranthis Bidentatae, the preferred Cortex Eucommiae carbon of the Cortex Eucommiae, the preferred Radix Glycyrrhizae Preparata of Radix Glycyrrhizae.
Pharmaceutical composition of the present invention adds conventional adjuvant by practice of pharmacy and makes the clinical dosage form of accepting, as capsule, pill, powder, tablet, granule, liniment, spray, ointment or emplastrum.
Pharmaceutical composition of the present invention is pure Chinese medicine preparation, to the treatment prolapse of lumbar intervertebral disc, and hyperosteogeny, femur head necrosis has tangible curative effect.The present invention has expelling wind and cold, dredge the meridian passage, blood circulation promoting and blood stasis dispelling, the routed pain relieving that disappears, impel inostosis, increase the effect of body immunity.The present invention is evident in efficacy, and the cure rate height does not contain the aconitine drug toxicity, has no side effect, and takes viscera harmless for a long time.
Following experimental example and embodiment are used to further specify but are not limited to the present invention.
Following experimental example is used to further specify the present invention:
Experimental example:
One, clinical data
Medicine composite for curing prolapse of lumbar intervertebral disc of the present invention and femur head necrosis 1050 examples, lumbar intervertebral disc protrusion people 1000 examples wherein, male 608 people, women 392 people, 20 years old-40 years old 300 people, 40 years old-50 years old 400 people, 50-70 year 300 people, effective 700 examples, produce effects 300 examples.Femur head necrosis patient's 50 examples, produce effects 25 examples, effective 23 examples, invalid 2 examples.
Two, diagnostic criteria
Make a definite diagnosis through film making.
Three, criterion of therapeutical effect
Produce effects: transference cure;
Effectively: original sx;
Invalid: symptom does not have improvement.
Four, Therapeutic Method
1, square medicine is formed
Radix Dipsaci 100g, Herba Taxilli 80g, Caulis Spatholobi 100g, Rhizoma Et Radix Notopterygii 60g, Radix Angelicae Pubescentis 60g, Olibanum 50g, Myrrha 50g, Ramulus Cinnamomi 30g, Radix Paeoniae Alba 50g, Radix Achyranthis Bidentatae 60g, Cortex Eucommiae carbon 50g, Scorpio 30g, Scolopendra 15g, Eupolyphaga Seu Steleophaga 60g, Herba Houttuyniae 60g, Radix Angelicae Sinensis 50g, Radix Glycyrrhizae Preparata 30g, Pheretima 50g, Radix Stephaniae Tetrandrae 50g.
2, preparation method
The above-mentioned raw materials medicine adds conventional adjuvant by practice of pharmacy and makes capsule.
3, usage and consumption
Each 4-8 grain, every day 2 times.
Five, therapeutic outcome:
Medicine composite for curing prolapse of lumbar intervertebral disc of the present invention and femur head necrosis 1050 examples, lumbar intervertebral disc protrusion people 1000 examples wherein, produce effects 300 examples, effective 700 examples, total effective rate 100%.Femur head necrosis patient's 50 examples, produce effects 25 examples, effective 23 examples, invalid 2 examples, inefficiency 4%, total effective rate 96%.
Six, model case:
Case 1: slowly * *: man, 50 years old, Hebei Qinglong County eight road river village people.Go to a doctor in October, 2007, readme pain in the lumbar region left side has a pain in the leg, and all sends out on foot and turns, and pain unbearably.By the X-ray film making, prolapse of lumbar intervertebral disc was fallen ill about 3 months.By diagnosis and treatment, take capsule of the present invention.Each 8, day clothes 2 times obviously take effect when taking to the 3rd week, and recovery from illness is now followed up a case by regular visits to and do not seen recurrence in 1 year after 2 months.
Case 2: the merchant *: man, 56 years old, Qinglong County Ba Daohe township, Hebei.Went to a doctor in 27th in December in 2006.The readme lumbago and skelalgia has 2 years, once removes county people's hospital's X-ray examination prolapse of lumbar intervertebral disc, doctor's announcement can only lean on rest, the plank bed of sleeping is faced upward, and recuperates several months, opens a little Western medicine again, after taking medicine, do not have any effect, and the state of an illness is more and more serious.After come here treatment upon somebody's introduction, take pill of the present invention after 2 months, recovery from illness is followed up a case by regular visits to and was not seen recurrence in 2 years.
Case 3: open * *: woman, 46 years old, slubbing ditch village, Qinglong County Ba Daohe township, Hebei province.Go to a doctor on July 26th, 2007, readme lumbago and skelalgia 1 year was obeyed a lot of medicines, did not all take effect, and showed hyperosteogeny by X-ray, fully recovered after two months through serveing on powder of the present invention, followed up a case by regular visits to not recurrence in 2 years.
Case 4: Guo *: man, 49 years old, chief of township's ditch village, river, Hebei province's Qinglong County eight road.Go to a doctor on January 2nd, 2007, when coming, the patient leaning on crutches, readme has the defect of femur head necrosis, and ill having had more than 6 years sought medical advice and medicine everywhere, to no effect, listen friend to introduce the spy and come the here treatment, after take capsule of the present invention, take four months after, thrown away one and turned, the happy three li multichannels of having walked are come the process that rehabilitation is told in here.After took again four months, thrown away another and turned, can also walk seven or eight lis.After taking four, five months medicine subsequently again, can do some basic farm work.
Case 5: Cao *: man, 48 years old, Qian Zhangzi village, Qinglong County Ba Daohe township, Hebei province.Going to a doctor readme on July 26th, 2006: suffered from ischemia femur head necrosis in 2004, more than a year, after inspection, take tablet of the present invention after 6 months, can participate in manual labor, continue to take rehabilitation after 6 months.
Case 6: open * *: man, 45 years old, Ding Zhang village, Qinglong County Lou Zhangzi township, Hebei province.Go to a doctor readme on March 20th, 2007: suffer from ischemia femur head necrosis, CT examination is found one-sided femur head necrosis, uses emplastrum of the present invention after inspection 4 months, and symptom makes moderate progress, and continues to use after 8 months and can participate in light physical labor.
Following embodiment all can realize the effect of above-mentioned experimental example.
The specific embodiment
Embodiment 1: the preparation of capsule
Radix Dipsaci 100kg Herba Taxilli 80kg Caulis Spatholobi 100kg
Rhizoma Et Radix Notopterygii 60kg Radix Angelicae Pubescentis 60kg Olibanum 50kg
Myrrha 50kg Ramulus Cinnamomi 30kg Radix Paeoniae Alba 50kg
Radix Achyranthis Bidentatae 60kg Cortex Eucommiae 50kg Scorpio 30kg
Scolopendra 15kg Eupolyphaga Seu Steleophaga 60kg Herba Houttuyniae 60kg
Radix Angelicae Sinensis 50kg Radix Glycyrrhizae 30kg Pheretima 50kg
Radix Stephaniae Tetrandrae 50kg;
The above-mentioned raw materials medicine is made the capsule of clinical acceptance according to the conventional adjuvant that common process adds on the pharmaceutics, each 4-8 grain, every day 2 times.
Embodiment 2: the preparation of pill
Radix Dipsaci 60kg Herba Taxilli 110kg Caulis Spatholobi 60kg
Rhizoma Et Radix Notopterygii 80kg Radix Angelicae Pubescentis 40kg Olibanum 65kg
Myrrha 35kg Ramulus Cinnamomi 35kg Radix Paeoniae Alba 35kg
Radix Achyranthis Bidentatae 80kg Cortex Eucommiae 35kg Scorpio 35kg
Scolopendra 10kg Eupolyphaga Seu Steleophaga 80kg Herba Houttuyniae 40kg
Radix Angelicae Sinensis 65kg Radix Glycyrrhizae 25kg Pheretima 65kg
Radix Stephaniae Tetrandrae 35kg;
The above-mentioned raw materials medicine is made the pill of clinical acceptance according to the conventional adjuvant that common process adds on the pharmaceutics.
Embodiment 3: the preparation of powder
Radix Dipsaci 140kg Herba Taxilli 50kg Caulis Spatholobi 140kg
Rhizoma Et Radix Notopterygii 40kg Radix Angelicae Pubescentis 80kg Olibanum 35kg
Myrrha 65kg Ramulus Cinnamomi 25kg Radix Paeoniae Alba 65kg
Radix Achyranthis Bidentatae 40kg Cortex Eucommiae 65kg Scorpio 25kg
Scolopendra 20kg Eupolyphaga Seu Steleophaga 40kg Herba Houttuyniae 80kg
Radix Angelicae Sinensis 35kg Radix Glycyrrhizae 35kg Pheretima 35kg
Radix Stephaniae Tetrandrae 65kg;
The above-mentioned raw materials medicine is made the powder of clinical acceptance according to the conventional adjuvant that common process adds on the pharmaceutics.
Embodiment 4: the preparation of tablet
Radix Dipsaci 100kg Herba Taxilli 80kg Caulis Spatholobi 100kg
Rhizoma Et Radix Notopterygii 60kg Radix Angelicae Pubescentis 60kg Olibanum 50kg
Myrrha 50kg Ramulus Cinnamomi 30kg Radix Paeoniae Alba 50kg
Radix Cyathulae 60kg Cortex Eucommiae carbon 50kg Scorpio 30kg
Scolopendra 15kg Eupolyphaga Seu Steleophaga 60kg Herba Houttuyniae 60kg
Radix Angelicae Sinensis 50kg Radix Glycyrrhizae Preparata 30kg Pheretima 50kg
Radix Stephaniae Tetrandrae 50kg;
The above-mentioned raw materials medicine is made the tablet of clinical acceptance according to the conventional adjuvant that common process adds on the pharmaceutics.
Embodiment 5: the preparation of emplastrum
Radix Dipsaci 120kg Herba Taxilli 90kg Caulis Spatholobi 120kg
Rhizoma Et Radix Notopterygii 50kg Radix Angelicae Pubescentis 50kg Olibanum 42kg
Myrrha 42kg Ramulus Cinnamomi 40kg Radix Paeoniae Alba 42kg
Radix Cyathulae 50kg Cortex Eucommiae carbon 42kg Scorpio 20kg
Scolopendra 13kg Eupolyphaga Seu Steleophaga 50kg Herba Houttuyniae 50kg
Radix Angelicae Sinensis 42kg Radix Glycyrrhizae Preparata 40kg Pheretima 42kg
Radix Stephaniae Tetrandrae 42kg;
The above-mentioned raw materials medicine is made the emplastrum of clinical acceptance according to the conventional adjuvant that common process adds on the pharmaceutics.

Claims (9)

1. pharmaceutical composition for the treatment of prolapse of lumbar intervertebral disc and femur head necrosis is characterized in that the crude drug of this pharmaceutical composition consists of:
Radix Dipsaci 50-150 weight portion Herba Taxilli 40-120 weight portion Caulis Spatholobi 50-150 weight portion
Rhizoma Et Radix Notopterygii 30-90 weight portion Radix Angelicae Pubescentis 30-90 weight portion Olibanum 25-75 weight portion
Myrrha 25-75 weight portion Ramulus Cinnamomi 15-45 weight portion Radix Paeoniae Alba 25-75 weight portion
Radix Achyranthis Bidentatae 30-90 weight portion Cortex Eucommiae 25-75 weight portion Scorpio 15-45 weight portion
Scolopendra 7-23 weight portion Eupolyphaga Seu Steleophaga 30-90 weight portion Herba Houttuyniae 30-90 weight portion
Radix Angelicae Sinensis 25-75 weight portion Radix Glycyrrhizae 15-45 weight portion Pheretima 25-75 weight portion
Radix Stephaniae Tetrandrae 25-75 weight portion.
2. pharmaceutical composition as claimed in claim 1 is characterized in that the crude drug of this pharmaceutical composition consists of:
Radix Dipsaci 100 weight portion Herba Taxillis 80 weight portion Caulis Spatholobis 100 weight portions
Rhizoma Et Radix Notopterygii 60 weight portion Radix Angelicae Pubescentiss 60 weight portion Olibanums 50 weight portions
The Myrrha 50 weight portion Ramulus Cinnamomi 30 weight portion Radix Paeoniae Albas 50 weight portions
The Radix Achyranthis Bidentatae 60 weight portion Cortexs Eucommiae 50 weight portion Scorpios 30 weight portions
Scolopendra 15 weight portion Eupolyphaga Seu Steleophagas 60 weight portion Herba Houttuyniae 60 weight portions
Radix Angelicae Sinensis 50 weight portion Radix Glycyrrhizaes 30 weight portion Pheretimas 50 weight portions
Radix Stephaniae Tetrandrae 50 weight portions.
3. pharmaceutical composition as claimed in claim 1 is characterized in that the crude drug of this pharmaceutical composition consists of:
Radix Dipsaci 60 weight portion Herba Taxillis 110 weight portion Caulis Spatholobis 60 weight portions
Rhizoma Et Radix Notopterygii 80 weight portion Radix Angelicae Pubescentiss 40 weight portion Olibanums 65 weight portions
The Myrrha 35 weight portion Ramulus Cinnamomi 35 weight portion Radix Paeoniae Albas 35 weight portions
The Radix Achyranthis Bidentatae 80 weight portion Cortexs Eucommiae 35 weight portion Scorpios 35 weight portions
Scolopendra 10 weight portion Eupolyphaga Seu Steleophagas 80 weight portion Herba Houttuyniae 40 weight portions
Radix Angelicae Sinensis 65 weight portion Radix Glycyrrhizaes 25 weight portion Pheretimas 65 weight portions
Radix Stephaniae Tetrandrae 35 weight portions.
4. pharmaceutical composition as claimed in claim 1 is characterized in that the crude drug of this pharmaceutical composition consists of:
Radix Dipsaci 140 weight portion Herba Taxillis 50 weight portion Caulis Spatholobis 140 weight portions
Rhizoma Et Radix Notopterygii 40 weight portion Radix Angelicae Pubescentiss 80 weight portion Olibanums 35 weight portions
The Myrrha 65 weight portion Ramulus Cinnamomi 25 weight portion Radix Paeoniae Albas 65 weight portions
The Radix Achyranthis Bidentatae 40 weight portion Cortexs Eucommiae 65 weight portion Scorpios 25 weight portions
Scolopendra 20 weight portion Eupolyphaga Seu Steleophagas 40 weight portion Herba Houttuyniae 80 weight portions
Radix Angelicae Sinensis 35 weight portion Radix Glycyrrhizaes 35 weight portion Pheretimas 35 weight portions
Radix Stephaniae Tetrandrae 65 weight portions.
5. as claim 1,2,3 or 4 arbitrary described pharmaceutical compositions, it is characterized in that described Radix Achyranthis Bidentatae is a Radix Cyathulae, the Cortex Eucommiae is a Cortex Eucommiae carbon, and Radix Glycyrrhizae is a Radix Glycyrrhizae Preparata.
6. as claim 1,2,3,4 or 5 arbitrary described pharmaceutical compositions, it is characterized in that the conventional adjuvant on this pharmaceutical composition adding pharmaceutics is made the dosage form of clinical acceptance.
7. pharmaceutical composition as claimed in claim 6 is characterized in that described dosage form is capsule, pill, powder, tablet, granule, liniment, spray, ointment or emplastrum.
8. as claim 1,2,3, the application of 4 or 5 arbitrary described pharmaceutical compositions in the medicine of preparation treatment prolapse of lumbar intervertebral disc.
9. as claim 1,2,3, the application of 4 or 5 arbitrary described pharmaceutical compositions in the medicine of preparation treatment femur head necrosis.
CN200810227336A 2008-11-27 2008-11-27 Medicinal composition for treating protrusion of lumbar vertebral disc and osteonecrosis of femeral head and usage thereof Pending CN101732470A (en)

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CN200810227336A CN101732470A (en) 2008-11-27 2008-11-27 Medicinal composition for treating protrusion of lumbar vertebral disc and osteonecrosis of femeral head and usage thereof

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104998009A (en) * 2015-08-07 2015-10-28 苏州神林堂中医药研究所 Traditional Chinese medicine composition for curing lumbar intervertebral disc protrusion
CN105963492A (en) * 2016-04-28 2016-09-28 谭永胜 Chinese herbal preparation for external application and application of Chinese herbal preparation
CN106668231A (en) * 2015-11-10 2017-05-17 马福奎 Traditional Chinese medicine for treating protrusion of lumbar intervertebral disc

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104998009A (en) * 2015-08-07 2015-10-28 苏州神林堂中医药研究所 Traditional Chinese medicine composition for curing lumbar intervertebral disc protrusion
CN106668231A (en) * 2015-11-10 2017-05-17 马福奎 Traditional Chinese medicine for treating protrusion of lumbar intervertebral disc
CN105963492A (en) * 2016-04-28 2016-09-28 谭永胜 Chinese herbal preparation for external application and application of Chinese herbal preparation

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Open date: 20100616