CN105267519A - Preparation method of traditional Chinese medicine pills for treating child bronchitis - Google Patents

Preparation method of traditional Chinese medicine pills for treating child bronchitis Download PDF

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Publication number
CN105267519A
CN105267519A CN201510770174.0A CN201510770174A CN105267519A CN 105267519 A CN105267519 A CN 105267519A CN 201510770174 A CN201510770174 A CN 201510770174A CN 105267519 A CN105267519 A CN 105267519A
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China
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chinese medicine
traditional chinese
afterwards
parts
medicine extract
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CN201510770174.0A
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Chinese (zh)
Inventor
王悦
张明
李晶晶
潘艳
刘磊
王祯莲
张治国
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Changzhou University
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Changzhou University
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Abstract

The invention relates to a preparation method of traditional Chinese medicine pills for treating child bronchitis and belongs to the technical field of medicine. The preparation method includes: using ephedra herb, mustard seed, pepperweed seed, prepared pinellia rhizome and great burdock achene as main traditional Chinese medicine raw materials; smashing, sieving and mixing; using alcohol for extraction to obtain active ingredients therein; obtaining traditional Chinese medicine paste through depressurized concentration; placing the traditional Chinese medicine paste into a pelletizer for pelleting, and drying to obtain the traditional Chinese medicine pills. The traditional Chinese medicine pills prepared by the method are extensive in raw material source, low in cost, simple in preparation process and free of side effect after long-time administration; the traditional Chinese medicine pills have obvious efficacy, and recovery time is shortened.

Description

A kind of preparation method for the treatment of infantile bronchitis Chinese medicinal pill
Technical field
The present invention relates to a kind of preparation method for the treatment of infantile bronchitis Chinese medicinal pill, belong to medical art.
Background technology
Infantile bronchitis, name of disease is " bronchiolitis ".The cause of disease of bronchiolitis is mainly respiratory syncytial virus, can account for 80% or more; Other is followed successively by adenovirus, parainfluenza virus, rhinovirus, influenza virus etc.; Minority case can be caused by mycoplasma pneumoniae, and after infecting virus, tiny capillary bronchus is congested, edema, and mucous secretion increases, and adds that downright bad mucomembranous epithelial cell comes off and blocks tube chamber, causes obvious emphysema and pulmonary atelectasis.Inflammation can involve alveolar usually, alveolar wall and interstitial lung, therefore can think that it is a kind of specific type of pneumonia.
Should send treatment to hospital in time after children's's morbidity, because mostly bronchiolitis is to be caused by viral infection, therefore morbidity generally does not need to use antibiotic therapy in early days.As can antibiotic therapy be used when the later stage of falling ill suspects secondary bacterial infection, treatment, based on symptomatic treatment, can be summarized as " calm cough-relieving ", in addition, good nursing is also very important, especially note not bothering infant, make it quiet and have a rest, indoor will keep certain humidity, children with serious disease can coordinate Neulized inhalation, and timely suction sputum, keep respiratory passage unblocked, also can use treatment by Chinese herbs.
Summary of the invention
The technical problem that the present invention mainly solves: involve great expense for the medicine for the treatment of infantile bronchitis at present, and there is side effect more in such medicine, long-term taking can grow to child body the defect had an impact, provide a kind of preparation method for the treatment of infantile bronchitis Chinese medicinal pill, the method is with Herba Ephedrae, Semen Sinapis, Semen Lepidii (Semen Descurainiae), Rhizoma Pinelliae Preparatum, Fructus Arctii is main raw material of Chinese medicine, by pulverize and sieve mixing after, lixiviate acquisition effective ingredient is wherein carried out with ethanol, Chinese medicine purees is obtained again by concentrating under reduced pressure, put into granulator granulation to be afterwards drying to obtain one and to treat infantile bronchitis Chinese medicinal pill.
In order to solve the problems of the technologies described above, the technical solution adopted in the present invention is:
(1) count by weight, take 10 ~ 15 portions of Herba Ephedraes, 5 ~ 10 parts of Semen Sinapiss, 10 ~ 12 parts of Semen Lepidii (Semen Descurainiae)s, 10 ~ 20 parts of Rhizoma Pinelliae Preparatum, 10 ~ 20 parts of Fructus Arctiis are put into jet mill together and pulverized;
(2) the important powder after above-mentioned pulverizing is crossed 30 mesh standard sieves, put into sonic oscillation instrument afterwards, sonic oscillation mixing 10 ~ 20min, supersonic frequency is 25 ~ 35kPa, and ultrasonic power is 100 ~ 200W;
(3) after, the important powder after sonic oscillation is moved into again and tell that separating apparatus disperses, obtain Chinese medicinal powder mixture;
(4) taking 100 ~ 200g Chinese medicinal powder mixture obtained above pours in 500mL beaker, add the alcoholic solution that 300 ~ 400mL mass concentration is 40%, shaking table oscillating reactions 2 ~ 3h, moves into afterwards in constant temperature resistance box, at 30 ~ 40 DEG C, leaves standstill lixiviate 5 ~ 7 days;
(5) mixed liquor after above-mentioned lixiviate is poured in concentrating under reduced pressure tank, to its evacuation, make pressure in tank reduce to 1200 ~ 1300Pa, to its concentrating under reduced pressure 3 ~ 4h, obtain pureed Chinese medicine extract;
(6) get the above-mentioned obtained pureed Chinese medicine extract of 50 ~ 100g again and put into ceramic pot, add 10 ~ 20m Fresh Egg clearly, be placed on afterwards on magnetic stirrer, stir 30 ~ 40min with the rotating speed of 200 ~ 300r/min, obtain thickness Chinese medicine extract;
(7) above-mentioned thickness Chinese medicine extract is poured into comminutor; carry out extruder grain, granular pill will be obtained afterwards and place in an oven, with the temperature drying 4 ~ 5h of 105 ~ 110 DEG C; be cooled to room temperature after taking-up and pack, obtaining a kind of Chinese medicinal pill for the treatment of infantile bronchitis.
The invention has the beneficial effects as follows:
(1) the Chinese medicinal pill raw material that the present invention obtains is easy to get, and with low cost, preparation process is simple;
(2) the Chinese medicinal pill long-term taking that the present invention obtains can not have side effects;
(3) take the Chinese medicinal pill that the present invention obtains, drug effect is obvious, time shorten of recovering.
Detailed description of the invention
Count by weight, take 10 ~ 15 portions of Herba Ephedraes, 5 ~ 10 parts of Semen Sinapiss, 10 ~ 12 parts of Semen Lepidii (Semen Descurainiae)s, 10 ~ 20 parts of Rhizoma Pinelliae Preparatum, 10 ~ 20 parts of Fructus Arctiis are put into jet mill together and pulverized; Important powder after above-mentioned pulverizing is crossed 30 mesh standard sieves, puts into sonic oscillation instrument afterwards, sonic oscillation mixing 10 ~ 20min, supersonic frequency is 25 ~ 35kPa, and ultrasonic power is 100 ~ 200W; Afterwards the important powder after sonic oscillation is moved into again and tell that separating apparatus disperses, obtain Chinese medicinal powder mixture; Take 100 ~ 200g Chinese medicinal powder mixture obtained above to pour in 500mL beaker, add the alcoholic solution that 300 ~ 400mL mass concentration is 40%, shaking table oscillating reactions 2 ~ 3h, move in constant temperature resistance box afterwards, at 30 ~ 40 DEG C, leave standstill lixiviate 5 ~ 7 days; Mixed liquor after above-mentioned lixiviate is poured in concentrating under reduced pressure tank, to its evacuation, make pressure in tank reduce to 1200 ~ 1300Pa, to its concentrating under reduced pressure 3 ~ 4h, obtain pureed Chinese medicine extract; Get the above-mentioned obtained pureed Chinese medicine extract of 50 ~ 100g again and put into ceramic pot, add 10 ~ 20m Fresh Egg clearly, be placed on afterwards on magnetic stirrer, stir 30 ~ 40min with the rotating speed of 200 ~ 300r/min, obtain thickness Chinese medicine extract; Pour above-mentioned thickness Chinese medicine extract into comminutor; carry out extruder grain, granular pill will be obtained afterwards and place in an oven, with the temperature drying 4 ~ 5h of 105 ~ 110 DEG C; be cooled to room temperature after taking-up and pack, obtaining a kind of Chinese medicinal pill for the treatment of infantile bronchitis.
Example 1
Count by weight, take 10 portions of Herba Ephedraes, 5 parts of Semen Sinapiss, 10 parts of Semen Lepidii (Semen Descurainiae)s, 10 parts of Rhizoma Pinelliae Preparatum, 10 parts of Fructus Arctiis are put into jet mill together and pulverized; Important powder after above-mentioned pulverizing is crossed 30 mesh standard sieves, puts into sonic oscillation instrument afterwards, sonic oscillation mixing 10min, supersonic frequency is 25kPa, and ultrasonic power is 100W; Afterwards the important powder after sonic oscillation is moved into again and tell that separating apparatus disperses, obtain Chinese medicinal powder mixture; Take 100g Chinese medicinal powder mixture obtained above to pour in 500mL beaker, add the alcoholic solution that 300mL mass concentration is 40%, shaking table oscillating reactions 2h, move in constant temperature resistance box afterwards, at 30 DEG C, leave standstill lixiviate 5 days; Mixed liquor after above-mentioned lixiviate is poured in concentrating under reduced pressure tank, to its evacuation, make pressure in tank reduce to 1200Pa, to its concentrating under reduced pressure 3h, obtain pureed Chinese medicine extract; Get the above-mentioned obtained pureed Chinese medicine extract of 50g again and put into ceramic pot, add 10m Fresh Egg clearly, be placed on afterwards on magnetic stirrer, stir 30min with the rotating speed of 200r/min, obtain thickness Chinese medicine extract; Pour above-mentioned thickness Chinese medicine extract into comminutor, carry out extruder grain, granular pill will be obtained afterwards and place in an oven, with the dry 4h of the temperature of 105 DEG C, be cooled to room temperature after taking-up and pack, obtaining a kind of Chinese medicinal pill for the treatment of infantile bronchitis.
Example 2
Count by weight, take 13 portions of Herba Ephedraes, 8 parts of Semen Sinapiss, 11 parts of Semen Lepidii (Semen Descurainiae)s, 15 parts of Rhizoma Pinelliae Preparatum, 15 parts of Fructus Arctiis are put into jet mill together and pulverized; Important powder after above-mentioned pulverizing is crossed 30 mesh standard sieves, puts into sonic oscillation instrument afterwards, sonic oscillation mixing 15min, supersonic frequency is 30kPa, and ultrasonic power is 150W; Afterwards the important powder after sonic oscillation is moved into again and tell that separating apparatus disperses, obtain Chinese medicinal powder mixture; Take 150g Chinese medicinal powder mixture obtained above to pour in 500mL beaker, add the alcoholic solution that 350mL mass concentration is 40%, shaking table oscillating reactions 2h, move in constant temperature resistance box afterwards, at 35 DEG C, leave standstill lixiviate 6 days; Mixed liquor after above-mentioned lixiviate is poured in concentrating under reduced pressure tank, to its evacuation, make pressure in tank reduce to 1250Pa, to its concentrating under reduced pressure 3h, obtain pureed Chinese medicine extract; Get the above-mentioned obtained pureed Chinese medicine extract of 80g again and put into ceramic pot, add 15m Fresh Egg clearly, be placed on afterwards on magnetic stirrer, stir 35min with the rotating speed of 250r/min, obtain thickness Chinese medicine extract; Pour above-mentioned thickness Chinese medicine extract into comminutor, carry out extruder grain, granular pill will be obtained afterwards and place in an oven, with the dry 4h of the temperature of 108 DEG C, be cooled to room temperature after taking-up and pack, obtaining a kind of Chinese medicinal pill for the treatment of infantile bronchitis.

Claims (1)

1. treat a preparation method for infantile bronchitis Chinese medicinal pill, it is characterized in that concrete preparation process is:
(1) count by weight, take 10 ~ 15 portions of Herba Ephedraes, 5 ~ 10 parts of Semen Sinapiss, 10 ~ 12 parts of Semen Lepidii (Semen Descurainiae)s, 10 ~ 20 parts of Rhizoma Pinelliae Preparatum, 10 ~ 20 parts of Fructus Arctiis are put into jet mill together and pulverized;
(2) the important powder after above-mentioned pulverizing is crossed 30 mesh standard sieves, put into sonic oscillation instrument afterwards, sonic oscillation mixing 10 ~ 20min, supersonic frequency is 25 ~ 35kPa, and ultrasonic power is 100 ~ 200W;
(3) after, the important powder after sonic oscillation is moved into again and tell that separating apparatus disperses, obtain Chinese medicinal powder mixture;
(4) taking 100 ~ 200g Chinese medicinal powder mixture obtained above pours in 500mL beaker, add the alcoholic solution that 300 ~ 400mL mass concentration is 40%, shaking table oscillating reactions 2 ~ 3h, moves into afterwards in constant temperature resistance box, at 30 ~ 40 DEG C, leaves standstill lixiviate 5 ~ 7 days;
(5) mixed liquor after above-mentioned lixiviate is poured in concentrating under reduced pressure tank, to its evacuation, make pressure in tank reduce to 1200 ~ 1300Pa, to its concentrating under reduced pressure 3 ~ 4h, obtain pureed Chinese medicine extract;
(6) get the above-mentioned obtained pureed Chinese medicine extract of 50 ~ 100g again and put into ceramic pot, add 10 ~ 20m Fresh Egg clearly, be placed on afterwards on magnetic stirrer, stir 30 ~ 40min with the rotating speed of 200 ~ 300r/min, obtain thickness Chinese medicine extract;
(7) above-mentioned thickness Chinese medicine extract is poured into comminutor; carry out extruder grain, granular pill will be obtained afterwards and place in an oven, with the temperature drying 4 ~ 5h of 105 ~ 110 DEG C; be cooled to room temperature after taking-up and pack, obtaining a kind of Chinese medicinal pill for the treatment of infantile bronchitis.
CN201510770174.0A 2015-11-12 2015-11-12 Preparation method of traditional Chinese medicine pills for treating child bronchitis Pending CN105267519A (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102406748A (en) * 2011-11-22 2012-04-11 荣成市交通诊所 Chinese medicinal composition for treating child bronchitis
CN102512579B (en) * 2011-12-27 2013-06-12 彭建 Chinese medicine for adjuvant therapy of infant bronchitis or pneumonia
CN103933343B (en) * 2014-04-08 2015-08-12 仲法维 A kind of Chinese medicinal pill for the treatment of bronchial asthma

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102406748A (en) * 2011-11-22 2012-04-11 荣成市交通诊所 Chinese medicinal composition for treating child bronchitis
CN102512579B (en) * 2011-12-27 2013-06-12 彭建 Chinese medicine for adjuvant therapy of infant bronchitis or pneumonia
CN103933343B (en) * 2014-04-08 2015-08-12 仲法维 A kind of Chinese medicinal pill for the treatment of bronchial asthma

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
李炯镇: ""自拟咳喘汤治疗小儿喘息样支气管炎80例临床观察"", 《新中医》 *

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