CN105250190B - A kind of Traditional Chinese medicine bacteriostatic skin care hand cleaning liquid and preparation method thereof - Google Patents
A kind of Traditional Chinese medicine bacteriostatic skin care hand cleaning liquid and preparation method thereof Download PDFInfo
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- CN105250190B CN105250190B CN201510830789.8A CN201510830789A CN105250190B CN 105250190 B CN105250190 B CN 105250190B CN 201510830789 A CN201510830789 A CN 201510830789A CN 105250190 B CN105250190 B CN 105250190B
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
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Abstract
The invention discloses a kind of Traditional Chinese medicine bacteriostatic skin care hand cleaning liquids, contain 10 20 parts by weight Chinese medicine extracts in every 100 parts by weight hand cleanser, 36 parts by weight sodium cocoyl glutamates, 7 15 parts by weight decyl glucosides, 35 parts by weight Cocoamidopropyl betaines, 0.5 1 parts by weight triethanolamines, 0.8 2 parts by weight of glycerin, 0.03 0.08 parts by weight Kathon CGs, the water of 0.1 0.2 parts by weight essence and surplus, wherein Chinese medicine extract are that bulk pharmaceutical chemicals extract to obtain by kuh-seng, sweet wormwood, kaempferia galamga, PORIA ALBA, campanulaceae.The Traditional Chinese medicine bacteriostatic skin care hand cleaning liquid of the present invention resists various bacteriums, has inhibiting effect to various pathogenic dermatophytes, also there is certain prevention effect to eczema and pruitus etc., and it is few with dosage, dirt-removing power is high, and bactericidal effect is good, the advantages that irritation is low, and feel is not fine and smooth, dry and astringent after washing.
Description
Technical field
The present invention relates to daily detergent, press down more particularly to a kind of Chinese medicine being prepared as raw material extraction using Chinese medicine
Bacterium skin care hand cleaning liquid and preparation method thereof.
Background technology
Renewal product of the hand cleanser as perfumed soap is the subdivided product in daily use chemicals market, has moisturizing, avoids secondary dirt
The many advantages such as dye.Hand cleanser is various in style currently on the market, but big multi-functional relatively simple.Though there is tool disinfecting and sterilizing functions
Hand cleanser products, but the disinfection hand cleanser based on Chinese herbal medicine is less, mostly adds the ingredients such as chemical bactericide and is made, it is long
Phase use is unfavorable to health.
Meanwhile the Traditional Chinese medicinal hand lotion with sterilizing function is mainly with cleaning, bacteriostasis efficacy currently on the market, to a variety of causes
Characteristic of disease dermatophyte unrestraint acts on, to pruitus etc. caused by eczema, mange, fungi without prevention effect.
Invention content
The object of the present invention is to provide a kind of highly effective and safes, have inhibiting effect to various pathogenic dermatophytes, to eczema
There is the preparation method of the Traditional Chinese medicine bacteriostatic skin care hand cleaning liquid and the hand cleanser that prevent effect with pruitus.
Contain 10-20 parts by weight Chinese medicine extracts, 3-6 weights in every 100 parts by weight Traditional Chinese medicine bacteriostatic skin care hand cleaning liquid of the present invention
Measure part sodium cocoyl glutamate, 7-15 parts by weight decyl glucosides, 3-5 parts by weight Cocoamidopropyl betaines, 0.5-1 weights
Amount part triethanolamine, 0.8-2 parts by weight of glycerin, 0.03-0.08 parts by weight Kathon CGs, 0.1-0.2 parts by weight essence and surplus
Water.
Wherein, it is raw material that the Chinese medicine extract, which is by the Chinese medicine of following parts by weight,：
Kuh-seng 40-45 sweet wormwoods 20-30
Kaempferia galamga 10-15 PORIA ALBAs 20-30
Campanulaceae 15-25
Extract the Chinese medicine extract of obtained d=1.5-1.8g/ml.
The specific preparation method of Traditional Chinese medicine bacteriostatic skin care hand cleaning liquid of the present invention includes the following steps：
1) Chinese medicine material, is weighed according to the parts by weight, is added water to cook after mixing three times, each amount of water is Chinese medicine weight
5-10 times of amount decocts 1 hour, merges decoction liquor twice, is concentrated into d=1.5-1.8g/ml, filters, obtains Chinese medicine extract；
2), by the sodium cocoyl glutamate of the parts by weight, decyl glucoside, Cocoamidopropyl betaine, three
Ethanol amine, glycerine are soluble in water successively, stir to after being uniformly dissolved, be added with stirring the parts by weight Chinese medicine extract,
Traditional Chinese medicine bacteriostatic skin care hand cleaning liquid is made until being completely dissolved in Kathon CG, essence.
Or Traditional Chinese medicine bacteriostatic skin care hand cleaning liquid is prepared by the following method：
1) other Chinese medicine materials for, weighing the parts by weight in addition to sweet wormwood add water to cook three times after mixing, add every time
Water is 5-10 times of Chinese medicine weight, is decocted 1 hour, and decoction liquor twice is merged；The sweet wormwood for weighing the parts by weight, with 8-10
The 10-15% ethyl alcohol of times weight impregnates 48-60h, then changes the water of same weight and impregnate 48-60h, merges soak twice；It will decoct
After liquid is mixed with soak, low temperature is concentrated into d=1.5-1.8g/ml, and filtering obtains Chinese medicine extract；
2), by the sodium cocoyl glutamate of the parts by weight, decyl glucoside, Cocoamidopropyl betaine, three
Ethanol amine, glycerine are soluble in water successively, stir to after being uniformly dissolved, be added with stirring the parts by weight Chinese medicine extract,
Traditional Chinese medicine bacteriostatic skin care hand cleaning liquid is made until being completely dissolved in Kathon CG, essence.
In Chinese medicine used in Traditional Chinese medicine bacteriostatic skin care hand cleaning liquid of the present invention, the main extract component of kuh-seng is alkaloids,
This constituents has apparent bacteriostasis to Escherichia coli, staphylococcus aureus, shigella dysenteriae and a variety of dermatophytes；Together
Shi Yinqi heat-clearing and damp-drying drugs can be used for eczema, wet sore, pruitus, the Prevention of mange leprosy etc..Sweet wormwood also known as abrotanum are
The herb of feverfew sweet wormwood, the clear abnormal heat of effect, cool blood is except steaming, and except steaming, preventing malaria is usually used in summer-heat evil fever, fever due to yin deficiency, night
It is hot early cool, hectic fever due to yin labor heat, malaria fever and chills, jaundice with damp-heat pathogen.Sweet wormwood decocting liquid to staphylococcus epidermis, micrococcus catarrhalis, bacillus anthracis,
Corynebacterium diphtheriae has stronger bacteriostasis, also has one to staphylococcus aureus, Pseudomonas aeruginosa, shigella dysenteriae, tuberculosis stalk bacterium etc.
Determine inhibiting effect.Sweet wormwood is rich in sesquiterpenoids, flavonoids, Coumarins and volatile ingredient and various glucosidases, with kuh-seng
Compatibility can be obviously improved the Antifungal activity of product, and with certain anti parasitic, antivirus action.Kaempferia galamga has promoting the circulation of qi
Phlegm, warming spleen and stomach for dispelling cold, appetite-stimulating and indigestion-relieving, regulating qi-flowing for relieving pain, invigorating the spleen disappear water, dry epidemic prevention the effect of, the soluble small molecular kaempferia galamga that contains
The flavone components such as phenol, Kaempferol can enhance product in effect anti-oxidant, in terms of whitening sun protection, and the citrin contained can both be protected
Active constituent exempts to aoxidize in shield product, and enables product mild moisturizing, vegetative cell.PORIA ALBA contains polysaccharide, triterpenes
Ingredient, energy dispelling speckles and whitening face, moist skin, can also enhance immune function, expand blood vessel.PORIA ALBA and kaempferia galamga compatible use, energy
The effect of black and white skin is removed in enhancing.Contain in campanulaceae water extract there are many saponin(e, polygalic acid, a large amount of synanthrin, platycodonin etc., to tissue
Protease has activation, can enhance the metabolism of cell, after having very strong wettability power, extract that product is added under room temperature
Product can be made to have preferable moisture-retaining capacity, long-time service that can restore hand skin natural mode.
Foundation《Disinfection technology standard》(version in 2002) detects the bacteriostasis property of Traditional Chinese medicine bacteriostatic skin care hand cleaning liquid of the present invention, tool
Body result is as follows.
A, Traditional Chinese medicine bacteriostatic skin care hand cleaning liquid stoste of the present invention is to a concentration of 3.76 × 104The coli test of cfu/ml is used
Bacteria suspension acts on 2min, each secondary equal ＞ 90% of bacteriostasis rate, and product has stronger bacteriostasis for Escherichia coli.
B, Traditional Chinese medicine bacteriostatic skin care hand cleaning liquid stoste of the present invention is to a concentration of 5.30 × 104The staphylococcus aureus of cfu/ml
Experiment bacteria suspension acts on 2min, each secondary equal ＞ 90% of bacteriostasis rate, and product has stronger antibacterial work for staphylococcus aureus
With.
C, Traditional Chinese medicine bacteriostatic skin care hand cleaning liquid stoste of the present invention is to a concentration of 3.38 × 104The Candida albicans of cfu/ml is tested
2min is acted on bacteria suspension, each secondary equal ＞ 90% of bacteriostasis rate, product has bacteriostasis for Candida albicans.
D, Traditional Chinese medicine bacteriostatic skin care hand cleaning liquid of the present invention is after 37 DEG C are stored 90 days, and stoste is to Escherichia coli, golden yellow Portugal
Grape coccus and Candida albicans experiment act on 2min with bacteria suspension, and each secondary equal ＞ 90% of bacteriostasis rate does not have with the fungistatic effect before storage
There were significant differences, shows to stablize the fungistatic effect of Escherichia coli, staphylococcus aureus, Candida albicans.
The Traditional Chinese medicine bacteriostatic skin care hand cleaning liquid of the present invention not only resists various bacteriums, has inhibition to make various pathogenic dermatophytes
With, also there is certain prevention effect to eczema and pruitus etc., and few with dosage, dirt-removing power is high, and bactericidal effect is good,
The advantages that irritation is low, and feel is not fine and smooth, dry and astringent after washing.Hand sanitizer formula of the present invention is simple, can meet modern market requirement
The demand of natural environmental-protective, Efficient antibacterial.
Specific implementation mode
Embodiment 1
It weighs 45 kg of kuh-seng, 30 kg of sweet wormwood, 20 kg of PORIA ALBA, kaempferia galamga 15kg, campanulaceae 15kg to be uniformly mixed, adds water
1200L controls temperature at 80 DEG C hereinafter, being filtered after decocting 1 hour, adds water 900L, filtered after decocting 1 hour.Merge twice
Decoction liquor is concentrated into 1.5g/ml and obtains Chinese medicine extract.
200kg purified waters are taken, slowly sequentially add sodium cocoyl glutamate 14kg, decyl glucoside under stiring
30kg, Cocoamidopropyl betaine 11kg, triethanolamine 1.5kg, 4 kg of glycerine are eventually adding until being completely dissolved uniformly
The essence of 50kg Chinese medicine extracts, 0.03% Kathon CG, 0.2 L, stirs evenly.
Traditional Chinese medicine bacteriostatic skin care hand cleaning liquid product is made through filling after the assay was approved.
Embodiment 2
It weighs 40 kg of kuh-seng, 20 kg of PORIA ALBA, kaempferia galamga 10kg, campanulaceae 20kg to be uniformly mixed, adds water 1000L, it is small to decoct 1
When after filter, add water 800L, filtered after decocting 1 hour, merge decoction liquor twice.20 kg of sweet wormwood is taken, 10% ethyl alcohol 200L is added
48h is impregnated, then changes water 200L and impregnates 48h, merges soak twice.After decoction liquor is mixed with soak, low temperature is concentrated into
1.6g/ml obtains Chinese medicine extract.
200kg purified waters are taken, slowly sequentially add sodium cocoyl glutamate 11kg, decyl glucoside under stiring
20kg, Cocoamidopropyl betaine 9kg, 2 kg of triethanolamine, 2.5 kg of glycerine are eventually adding until being completely dissolved uniformly
The essence of 30kg Chinese medicine extracts, 0.08% Kathon CG, 0.4 L, stirs evenly.
Traditional Chinese medicine bacteriostatic skin care hand cleaning liquid product is made through filling after the assay was approved.
Claims (3)
1. a kind of Traditional Chinese medicine bacteriostatic skin care hand cleaning liquid, 10-20 parts by weight Chinese medicine extracts, 3-6 are contained in every 100 parts by weight hand cleanser
Parts by weight sodium cocoyl glutamate, 7-15 parts by weight decyl glucosides, 3-5 parts by weight Cocoamidopropyl betaines, 0.5-1
Parts by weight triethanolamine, 0.8-2 parts by weight of glycerin, 0.03-0.08 parts by weight Kathon CGs, 0.1-0.2 parts by weight essence and surplus
Water；
Wherein, it is raw material that the Chinese medicine extract, which is by the Chinese medicine of following parts by weight,：
Kuh-seng 40-45 sweet wormwoods 20-30
Kaempferia galamga 10-15 PORIA ALBAs 20-30
Campanulaceae 15-25
The Chinese medicine extract extracted according to any one following method：
1) it is added water to cook twice after mixing, each amount of water is 5-10 times of Chinese medicine weight, is decocted 1 hour, and merging decocts twice
Liquid is concentrated into d=1.5-1.8g/ml, and Chinese medicine extract is obtained by filtration；
2) it is added water to cook twice after mixing other Chinese medicine materials in addition to sweet wormwood, each amount of water is the 5-10 of Chinese medicine weight
Times, it decocts 1 hour, merges decoction liquor twice；Sweet wormwood is impregnated into 48-60h with the 10-15% ethyl alcohol of 8-10 times of weight, then is changed same
The water of weight impregnates 48-60h, merges soak twice；After decoction liquor is mixed with soak, low temperature is concentrated into d=1.5-
Chinese medicine extract is obtained by filtration in 1.8g/ml.
2. a kind of preparation method of Traditional Chinese medicine bacteriostatic skin care hand cleaning liquid as described in claim 1, includes the following steps：
1) Chinese medicine material, is weighed according to the parts by weight, is added water to cook after mixing twice, each amount of water is Chinese medicine weight
It 5-10 times, decocts 1 hour, merges decoction liquor twice, be concentrated into d=1.5-1.8g/ml, filter, obtain Chinese medicine extract；
2), by the sodium cocoyl glutamate of the parts by weight, decyl glucoside, Cocoamidopropyl betaine, three ethyl alcohol
Amine, glycerine are soluble in water successively, stir to after being uniformly dissolved, be added with stirring the Chinese medicine extracts of the parts by weight, Kathon CG,
Traditional Chinese medicine bacteriostatic skin care hand cleaning liquid is made until being completely dissolved in essence.
3. a kind of preparation method of Traditional Chinese medicine bacteriostatic skin care hand cleaning liquid as described in claim 1, includes the following steps：
1) other Chinese medicine materials for, weighing the parts by weight in addition to sweet wormwood add water to cook twice, each amount of water after mixing
It is 5-10 times of Chinese medicine weight, decocts 1 hour, merges decoction liquor twice；The sweet wormwood for weighing the parts by weight, is weighed with 8-10 times
The 10-15% ethyl alcohol of amount impregnates 48-60h, then changes the water immersion 48-60h of same weight, merges soak twice；By decoction liquor with
After soak mixing, low temperature is concentrated into d=1.5-1.8g/ml, and filtering obtains Chinese medicine extract；
2), by the sodium cocoyl glutamate of the parts by weight, decyl glucoside, Cocoamidopropyl betaine, three ethyl alcohol
Amine, glycerine are soluble in water successively, stir to after being uniformly dissolved, be added with stirring the Chinese medicine extracts of the parts by weight, Kathon CG,
Traditional Chinese medicine bacteriostatic skin care hand cleaning liquid is made until being completely dissolved in essence.
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Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN106176317A (en) * | 2016-08-26 | 2016-12-07 | 南京巨鲨显示科技有限公司 | A kind of Flos Inulae quintessence oil bacteriostatic hand sanitizer |
| CN106852796A (en) * | 2016-12-09 | 2017-06-16 | 苏州纳贝通环境科技有限公司 | A kind of man's oil control and acne removal mildy wash and preparation method thereof |
| CN106701357A (en) * | 2016-12-16 | 2017-05-24 | 天峨县全盛蜂业科技有限公司 | Compound cleaning solution |
| CN109055058A (en) * | 2018-08-24 | 2018-12-21 | 中山市洁莹生物科技有限公司 | A kind of plant bacteriostatic hand sanitizer and preparation method thereof |
| CN111067849B (en) * | 2020-01-13 | 2023-07-28 | 广州洁宜日化用品有限公司 | Preparation method of hand sanitizer suitable for baby skin |
| CN112120982B (en) * | 2020-09-29 | 2022-02-18 | 亳州市惠丰生物科技有限公司 | Preparation method of traditional Chinese medicine antibacterial hand sanitizer |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102423291A (en) * | 2011-12-30 | 2012-04-25 | 山西振东制药股份有限公司 | Traditional Chinese medicine antibiotic skincare hand cleanser and preparation method thereof |
| CN103126972A (en) * | 2013-03-19 | 2013-06-05 | 天津厚实科技有限公司 | Skin care composition with anti-aging and whitening effects |
| CN104306189A (en) * | 2014-09-21 | 2015-01-28 | 青岛特瑞信电子科技有限公司 | Skin care and bactericidal hand washing solution |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102423291A (en) * | 2011-12-30 | 2012-04-25 | 山西振东制药股份有限公司 | Traditional Chinese medicine antibiotic skincare hand cleanser and preparation method thereof |
| CN103126972A (en) * | 2013-03-19 | 2013-06-05 | 天津厚实科技有限公司 | Skin care composition with anti-aging and whitening effects |
| CN104306189A (en) * | 2014-09-21 | 2015-01-28 | 青岛特瑞信电子科技有限公司 | Skin care and bactericidal hand washing solution |
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Address after: 047100 Zhendong science and Technology Park, Guangming South Road, Changzhi County, Changzhi City, Shanxi Province Patentee after: Shanxi Zhendong Health Biotechnology Co.,Ltd. Address before: 047100 Shanxi city of Changzhi province Changzhi County Guangming Road Zhendong Science Park Patentee before: SHANXI ZHENDONG HOUSEHOLD HEALTH CARE PRODUCTS Co.,Ltd. |
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