CN105232674A - Medicinal preparation for treating scapulohumeral periarthritis - Google Patents
Medicinal preparation for treating scapulohumeral periarthritis Download PDFInfo
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- CN105232674A CN105232674A CN201510802217.9A CN201510802217A CN105232674A CN 105232674 A CN105232674 A CN 105232674A CN 201510802217 A CN201510802217 A CN 201510802217A CN 105232674 A CN105232674 A CN 105232674A
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Abstract
The invention belongs to the field of traditional Chinese medicine preparations and particularly provides a medicinal preparation for treating scapulohumeral periarthritis. The medicinal preparation is prepared from 25 parts of cinnamomum japonicum, 28 parts of stellaria vestita kurz, 20 parts of jasminum floridum, 20 parts of scrophulariaceae limnophila aromatica, 25 parts of divaricate saposhnikovia roots, 22 parts of pawpaws, 26 parts of dandelions, 15 parts of notopterygium roots, 25 parts of angelica sinensis, 28 parts of the seed of cowherb, 15 parts of radix clematidis, 15 parts of caulis spatholobi and 5 parts of liquorice. The medicinal preparation can treat scapulohumeral periarthritis.
Description
Technical field
The present invention relates to technical field of traditional Chinese medicine preparation, be specifically related to a kind of pharmaceutical preparation being used for the treatment of scapulohumeral periarthritis and its preparation method and application.
Background technology
Scapulohumeral periarthritis, is commonly called as solidifying shoulder, scapulohumeral periarthritis or congealed shoulder.Onset is many because of shoulder joint surrounding tissue, if flesh thorax, synovial bursa etc. are by caused by freezing, wound, infection.Many patients are caused by rheumatism.Its cardinal symptom is neck shoulder constant pain, and ipsilateral upper limb is raised, rotate, swing is limited, meets wind and meets cold sensation and have heavy dull pain.As treated not in time, delay and with the passing of time can make joint accretion, ipsilateral upper limb attenuates, and unablely even forms disuse atrophy.This disease is more common in the middle age of about 50 years old, and the young and the old also has generation.Pain feature is arm once dynamic pain, motionless bitterly or slightly not bitterly, comb one's hair, wear the clothes, extract, elevate and all have any problem.Can hurt like hell when showing effect serious, lie awake all night.For this reason, the needs that the medicine developing more cure scapulohumeral periarthritis safely and effectively meets clinical treatment are bursting to.
Summary of the invention
In order to solve the problem, the object of the present invention is to provide a kind of can the Chinese medicine preparation of cure scapulohumeral periarthritis disease.In order to reach this object, adopt following technical scheme:
Technical scheme: a kind of pharmaceutical preparation being used for the treatment of scapulohumeral periarthritis, the active component contained by it is extracted by following raw materials in part by weight medicine and is prepared from: Cinnamomum japonica 25 parts, mountain valley with clumps of trees and bamboo aunt grass 28 parts, Jasminum floridum Bge. 20 parts, cough-relieving grass 20 parts, Radix Saposhnikoviae 25 parts, Fructus Chaenomelis 22 parts, Herba Taraxaci 26 parts, Rhizoma Et Radix Notopterygii 15 parts, Radix Angelicae Sinensis 25 parts, Semen Vaccariae 28 parts, Radix Clematidis 15 parts, Caulis Spatholobi 15 parts, 5 parts, Radix Glycyrrhizae.
The described pharmaceutical preparation being used for the treatment of scapulohumeral periarthritis, dosage form is pharmaceutically acceptable granule, tablet, capsule.
The described pharmaceutical preparation being used for the treatment of scapulohumeral periarthritis, preparation process is: get above-mentioned Chinese medicine, add the water of medical material 10 times of weight, soak 0.5h, decoct 1 hour, filter, medicinal residues add the water of medical material 8 times of weight again, decoct 1 hour, medicinal liquid leaches, merge twice decoction liquor, being evaporated to 60 DEG C of relative densities is 1.05, adding ethanol makes the percent by volume of alcohol content reach 75%, stir, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.25, and reclaim ethanol, obtain concentrated solution, by concentrated solution spraying dry, spray drying condition is: inlet temperature is 100 DEG C, leaving air temp is 90 DEG C, temperature of charge is 70 DEG C, atomizing pressure is 0.2 MPa, spray velocity is 10ml/s, add adjuvant and make capsule, tablet, granule.
The application in cure scapulohumeral periarthritis medicine is being prepared in the described pharmaceutical preparation being used for the treatment of scapulohumeral periarthritis.
Cinnamomum japonica, Latin is called CinnamomumjaponicumSieb., Ranales canella, aiphyllium, high 10-15 rice, diameter of a cross-section of a tree trunk 1.3 meters above the ground 30-35 centimetre.Warming spleen and stomach for dispelling cold, regulating QI to relieve pain.For stomachache, stomachache, rheumatic arthritis; Traumatic injury is controlled in external.The present invention is used as medicine with leaf.
Mountain valley with clumps of trees and bamboo aunt grass (formal name used at school: Stellariavestita) is the plant of Caryophyllaceae Stellaria.Herb hyoscine, can relaxing muscles and tendons to promote blood circulation.
Jasminum floridum Bge. is the root that Oleaceae plants visits the spring, granulation promoting, and convergence, controls knife injury.
Cough-relieving grass, Classification system Limnophilaaromatica (Lam.) Merr.LimnophilagratissimaBlume, with all herbal medicine.The whole year can adopt, and cleans, using fresh herb or dry.Clearing away lung-heat to relieve cough, removing toxic substances and promoting subsidence of swelling.For flu, cough, pertussis, venom, carbuncle pyogenic infections from tumour or sore.All the other Chinese medicines are pharmacopeia kind.
Beneficial effect: the traditional Chinese medical science thinks that yang-energy is weak, healthy energy is gradually damaged, deficiency of the liver and kindey, deficient qi and blood, battalion defends imbalance, so that muscle arteries and veins muscle lose moisten foster, meet outside rheumatism cold-evil and invade, easily make coagulation of QI-blood, yang-energy is cloth not, venation obstructed thus send out scapulohumeral periarthritis, Cinnamomum japonica of the present invention, mountain valley with clumps of trees and bamboo aunt grass, Jasminum floridum Bge., cough-relieving grass, Radix Saposhnikoviae, Fructus Chaenomelis, Herba Taraxaci, Rhizoma Et Radix Notopterygii blood circulation promoting and blood stasis dispelling is monarch drug, Radix Angelicae Sinensis, Semen Vaccariae, Radix Clematidis, Caulis Spatholobi supplementing QI and nourishing YIN, promoting the circulation of QI to relieve pain are ministerial drug, Radix Glycyrrhizae is adjuvant, the mutual compatibility of full side, blood circulation promoting and blood stasis dispelling, promoting the circulation of QI to relieve pain, cure scapulohumeral periarthritis successful.
Detailed description of the invention
Form by the following examples, foregoing of the present invention is described in further detail again, but this should be interpreted as that the scope of the above-mentioned theme of the present invention is only limitted to following example, all technology realized based on foregoing of the present invention all belong to scope of the present invention.
1, the preparation of granule embodiment: get Cinnamomum japonica 25g, mountain valley with clumps of trees and bamboo aunt grass 28g, Jasminum floridum Bge. 20g, cough-relieving grass 20g, Radix Saposhnikoviae 25g, Fructus Chaenomelis 22g, Herba Taraxaci 26g, Rhizoma Et Radix Notopterygii 15g, Radix Angelicae Sinensis 25g, Semen Vaccariae 28g, Radix Clematidis 15g, Caulis Spatholobi 15g, Radix Glycyrrhizae 5g, add the water of medical material 10 times of weight, soak 0.5h, decoct 1 hour, filter, medicinal residues add the water of medical material 8 times of weight again, decoct 1 hour, medicinal liquid leaches, merge twice decoction liquor, being evaporated to 60 DEG C of relative densities is 1.05, adding ethanol makes the percent by volume of alcohol content reach 75%, stir, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.25, and reclaim ethanol, obtain concentrated solution, by concentrated solution spraying dry, spray drying condition is: inlet temperature is 100 DEG C, leaving air temp is 90 DEG C, temperature of charge is 70 DEG C, atomizing pressure is 0.2 MPa, spray velocity is 10ml/s, add starch 50g, granulate, make granule.
2, the preparation of Tablets Example: get Cinnamomum japonica 25g, mountain valley with clumps of trees and bamboo aunt grass 28g, Jasminum floridum Bge. 20g, cough-relieving grass 20g, Radix Saposhnikoviae 25g, Fructus Chaenomelis 22g, Herba Taraxaci 26g, Rhizoma Et Radix Notopterygii 15g, Radix Angelicae Sinensis 25g, Semen Vaccariae 28g, Radix Clematidis 15g, Caulis Spatholobi 15g, Radix Glycyrrhizae 5g, add the water of medical material 10 times of weight, soak 0.5h, decoct 1 hour, filter, medicinal residues add the water of medical material 8 times of weight again, decoct 1 hour, medicinal liquid leaches, merge twice decoction liquor, being evaporated to 60 DEG C of relative densities is 1.05, adding ethanol makes the percent by volume of alcohol content reach 75%, stir, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.25, and reclaim ethanol, obtain concentrated solution, by concentrated solution spraying dry, spray drying condition is: inlet temperature is 100 DEG C, leaving air temp is 90 DEG C, temperature of charge is 70 DEG C, atomizing pressure is 0.2 MPa, spray velocity is 10ml/s, add dextrin 50g, granulate, tabletting, make tablet.
3, the preparation of capsule embodiment: get Cinnamomum japonica 25g, mountain valley with clumps of trees and bamboo aunt grass 28g, Jasminum floridum Bge. 20g, cough-relieving grass 20g, Radix Saposhnikoviae 25g, Fructus Chaenomelis 22g, Herba Taraxaci 26g, Rhizoma Et Radix Notopterygii 15g, Radix Angelicae Sinensis 25g, Semen Vaccariae 28g, Radix Clematidis 15g, Caulis Spatholobi 15g, Radix Glycyrrhizae 5g, add the water of medical material 10 times of weight, soak 0.5h, decoct 1 hour, filter, medicinal residues add the water of medical material 8 times of weight again, decoct 1 hour, medicinal liquid leaches, merge twice decoction liquor, being evaporated to 60 DEG C of relative densities is 1.05, adding ethanol makes the percent by volume of alcohol content reach 75%, stir, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.25, and reclaim ethanol, obtain concentrated solution, by concentrated solution spraying dry, spray drying condition is: inlet temperature is 100 DEG C, leaving air temp is 90 DEG C, temperature of charge is 70 DEG C, atomizing pressure is 0.2 MPa, spray velocity is 10ml/s, add starch 50g, granulate, fill, make capsule.
4, the present invention is to the clinical research of scapulohumeral periarthritis
4.1, physical data: inventor collects the out-patient of 60 routine scapulohumeral periarthritis altogether between in June ,-2013 in August, 2012, age 45-64 year, course of disease 1-4.Be divided at random: treatment group 30 example, blank group 30 example.The two groups of data such as age, state of an illness there was no significant differences, have comparability.
Diagnostic criteria: (1) more than 40 ~ 50 years old person in middle and old age, often have rheumatism attacked by the cold and evil history or trauma history.(2) shoulder pain and movable pain, night increases the weight of, and can radiate in one's hands, but numbness is abnormal.(3) the especially above act of shoulder mobility, abduction, inside and outside revolve limited.(4) shoulder tenderness, particularly brachial biceps ditch.(5) shoulder muscle spasm or amyotrophy.(6) x-ray and the general discovery without exception of laboratory examination.
4.2, test method
4.2.1 the oral the present invention for the treatment of group is according to the obtained granule of specific embodiment 2, sooner or later each once.15 days courses for the treatment of.
4.2.2 blank group oral placebo granule, sooner or later respectively once.15 days courses for the treatment of.
4.3, criterion of therapeutical effect and therapeutic outcome
4.3.1 criterion of therapeutical effect
Recovery from illness: clinical symptoms all disappears.Take a turn for the better: clinical symptom relief, the state of an illness is controlled.Invalid: clinical symptoms is without being clearly better or increasing the weight of.
4.3.2 statistical result is treated in table 1.
Table 1 liang group comparitive study
| Group | n | Recovery from illness | Take a turn for the better | Invalid | Total effective rate (%) |
| Treatment group | 30 | 8 | 20 | 2 | 93.3 |
| Blank group | 30 | 2 | 1 | 27 | 10 |
Visible, the medicine that the present invention obtains can safe and effective cure scapulohumeral periarthritis, and has no side effect.
Claims (4)
1. one kind is used for the treatment of the pharmaceutical preparation of scapulohumeral periarthritis, it is characterized in that, the active component contained by it is extracted by following raw materials in part by weight medicine and is prepared from: Cinnamomum japonica 25 parts, mountain valley with clumps of trees and bamboo aunt grass 28 parts, Jasminum floridum Bge. 20 parts, cough-relieving grass 20 parts, Radix Saposhnikoviae 25 parts, Fructus Chaenomelis 22 parts, Herba Taraxaci 26 parts, Rhizoma Et Radix Notopterygii 15 parts, Radix Angelicae Sinensis 25 parts, Semen Vaccariae 28 parts, Radix Clematidis 15 parts, Caulis Spatholobi 15 parts, 5 parts, Radix Glycyrrhizae.
2. be used for the treatment of the pharmaceutical preparation of scapulohumeral periarthritis as claimed in claim 1, it is characterized in that, dosage form is pharmaceutically acceptable granule, tablet, capsule.
3. be used for the treatment of the pharmaceutical preparation of scapulohumeral periarthritis as claimed in claim 1, it is characterized in that, preparation process is: get above-mentioned Chinese medicine, add the water of medical material 10 times of weight, soak 0.5h, decoct 1 hour, filter, medicinal residues add the water of medical material 8 times of weight again, decoct 1 hour, medicinal liquid leaches, merge twice decoction liquor, being evaporated to 60 DEG C of relative densities is 1.05, adding ethanol makes the percent by volume of alcohol content reach 75%, stir, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.25, and reclaim ethanol, obtain concentrated solution, by concentrated solution spraying dry, spray drying condition is: inlet temperature is 100 DEG C, leaving air temp is 90 DEG C, temperature of charge is 70 DEG C, atomizing pressure is 0.2 MPa, spray velocity is 10ml/s, add adjuvant and make capsule, tablet, granule.
4. be used for the treatment of the application of pharmaceutical preparation in cure scapulohumeral periarthritis medicine of scapulohumeral periarthritis according to claim 1.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105688156A (en) * | 2016-03-17 | 2016-06-22 | 王甲林 | Pharmaceutical composition for treating scapulohumeral periarthritis and preparation method thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105688156A (en) * | 2016-03-17 | 2016-06-22 | 王甲林 | Pharmaceutical composition for treating scapulohumeral periarthritis and preparation method thereof |
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Application publication date: 20160113 |
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