CN105213838A - A kind of preparation and method for making of preventing and treating spontaneous perspiration - Google Patents
A kind of preparation and method for making of preventing and treating spontaneous perspiration Download PDFInfo
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Abstract
The invention discloses a kind of preparation preventing and treating spontaneous perspiration, be prepared from primarily of following bulk drugs, be mass parts: Rhizoma Atractylodis Macrocephalae 8-12; Radix vignae sinensis 10-14; Radix Cynanchi Amplexicaulis 9-13; Stone maple medicine 7-12; Caulis Stelmatocryptonis khasiani 6-13; Herba Hyperici Sampsonii 9-14; Wild Pedicellus et Pericarpium Trapae 7-13; Radix seu Folium Rubi Pinfaensis 8-14; Radix Caraganae intermediae 10-15; Fructus Corni 8-13; Mactraantiquata Spengler 6-12; Fructus Tritici Levis 8-15; Radix Calystegiae sepii 10-16; Herba Bulbophylli inconspicui 9-12; Radix Oryzae Glutinosae 7-14.The present invention sums up through clinical practice for many years and forms, and has effect of supplementing QI and nourishing YIN, liver and kidney tonifying, evident in efficacy.
Description
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to a kind of preparation and method for making of preventing and treating spontaneous perspiration.
Background technology
Spontaneous perspiration refers to not because of tired movable, not because of sky heat and warm performance of taking factors such as dispersing medicine and natural sweating of wearing the clothes.The how main void of disease of spontaneous perspiration, has that the deficiency of vital energy, yang deficiency are not, main pathogenesis is imbalance of YIN and YANG, and space between skin and muscles is solid, and causes perspiration and leak.Ferritic is weak, the people of the full void of prolonged illness, and positive QI-insufficiency, pauses tired common spontaneous perspiration; Cough with asthma day Sheng people, insufficiency of lung-QI, with the passing of time, loose striac of the skin and muscles, instability of surface, space between skin and muscles using pungent drugs for dispersion and bitter drugs for purgation can cause spontaneous perspiration to the deficiency of vital energy.Summer-heat impairment of YANG, or damp and hot interior strongly fragrant, or the people of exterior deficiency is micro-by ailment said due to cold or exposure, so that disharmony of nutrient QI with defensive QI, defend outer mistake department, can spontaneous perspiration be caused.Clinical signs is perspiration and aversion to wind, moves then easily very, easily catches a cold, lustreless complexion, headache, white and thin fur, thready and weak pulse.
Publication No. CN104474343A(application number 201410756899.X) Chinese patent literature disclose a kind of Chinese medicine being used for the treatment of spontaneous perspiration, it is prepared from by the raw medicinal material of following weight proportion: Fructus Tritici Levis 10 parts, Radix Oryzae Glutinosae 10 parts, Concha Ostreae 9 parts, Os Draconis 9 parts, Radix Codonopsis 8 parts, Rhizoma Polygonati 8 parts, Fructus Schisandrae Chinensis 3 parts, Radix Ophiopogonis 6 parts.Publication No. CN103040906A(application number 201310018999.8) Chinese patent literature disclose a kind of Chinese medicine composition being used for the treatment of disease of spontaneous perspiration and preparation method thereof.Chinese medicine composition provided by the invention is the medicament be made up of the raw material of Chinese medicine of following weight portion: Radix Pseudostellariae 20 ~ 80 parts, Radix Wahlenbergiae Marginatae 20 ~ 80 parts.Publication No. CN103110710A(application number 201210529339.1) Chinese patent literature disclose a kind of medicine pill for the treatment of spontaneous perspiration, the weight of each raw material of Chinese medicine consists of: the Radix Astragali 5 parts, the Radix Paeoniae Alba 4 parts, Ramulus Cinnamomi 1 part, 4 parts, Poria, Fructus Schisandrae Chinensis 3 parts, Fructus Corni 3 parts, the Rhizoma Atractylodis Macrocephalae 4 parts, Galla Chinensis 1 part, Radix Salviae Miltiorrhizae 5 parts and 10 parts, Fructus Jujubae, have effect of invigorating the spleen and replenishing QI, strengthening superficial resistance to stop perspiration.
Be used for the treatment of the Chinese medicine of spontaneous perspiration at present, because traditional Chinese medical science theory is different, curative effect is also uneven, is the selection of convenient patient, needs strengthening research, provides the Chinese medicine formula that a kind of curative effect is reliable, cheap.
Summary of the invention
For the problem of prior art, the object of this invention is to provide a kind of Be very effective, take preparation and the method for making of the wide control spontaneous perspiration of safe and applicable.
Technical scheme of the present invention is:
Prevent and treat a preparation for spontaneous perspiration, be prepared from primarily of following bulk drugs, be mass parts: Rhizoma Atractylodis Macrocephalae 8-12; Radix vignae sinensis 10-14; Radix Cynanchi Amplexicaulis 9-13; Stone maple medicine 7-12; Caulis Stelmatocryptonis khasiani 6-13; Herba Hyperici Sampsonii 9-14; Wild Pedicellus et Pericarpium Trapae 7-13; Radix seu Folium Rubi Pinfaensis 8-14; Radix Caraganae intermediae 10-15; Fructus Corni 8-13; Mactraantiquata Spengler 6-12; Fructus Tritici Levis 8-15; Radix Calystegiae sepii 10-16; Herba Bulbophylli inconspicui 9-12; Radix Oryzae Glutinosae 7-14.
Preferred version is, Rhizoma Atractylodis Macrocephalae 9-11; Radix vignae sinensis 11-13; Radix Cynanchi Amplexicaulis 10-12; Stone maple medicine 9-10; Caulis Stelmatocryptonis khasiani 8-11; Herba Hyperici Sampsonii 10-13; Wild Pedicellus et Pericarpium Trapae 8-12; Radix seu Folium Rubi Pinfaensis 10-12; Radix Caraganae intermediae 11-14; Fructus Corni 9-12; Mactraantiquata Spengler 8-10; Fructus Tritici Levis 10-13; Radix Calystegiae sepii 12-14; Herba Bulbophylli inconspicui 10-11; Radix Oryzae Glutinosae 9-12.
More preferably, the Rhizoma Atractylodis Macrocephalae 10; Radix vignae sinensis 12; Radix Cynanchi Amplexicaulis 11; Stone maple medicine 9.5; Caulis Stelmatocryptonis khasiani 9.5; Herba Hyperici Sampsonii 11.5; Wild Pedicellus et Pericarpium Trapae 10; Radix seu Folium Rubi Pinfaensis 11; Radix Caraganae intermediae 12.5; Fructus Corni 10.5; Mactraantiquata Spengler 9; Fructus Tritici Levis 11.5; Radix Calystegiae sepii 13; Herba Bulbophylli inconspicui 10.5; Radix Oryzae Glutinosae 10.5.
The preparation method of described preparation granules agent, step is as follows:
(1) get Radix Cynanchi Amplexicaulis, stone maple medicine, Herba Hyperici Sampsonii and Herba Bulbophylli inconspicui wash quickly clean, add yellow wine and soak 12-24 minute (preferably: soak 16-20 minute; Be more preferably: soak 18 minutes), take out and put into frying pan, the micro-stir-fry of slow fire is to dry, and taking-up cools;
(2) Fructus Corni and Mactraantiquata Spengler are cleaned pulverizing, add candy sugar powder mixing, the hydromel drenched into crude drug quality 1 times is mixed thoroughly, is placed in steamer, and Steam by water bath 15-25 minute (preferred: Steam by water bath 18-22 minute; Be more preferably: Steam by water bath 20 minutes), take out, drying is pulverized;
(3) getting Testa Tritici is placed in frying pan, adds rice vinegar and mixes moistening 8-18 minute thoroughly (preferably: mix moistening 10-16 minute thoroughly; Be more preferably: mix moistening thoroughly 13 minutes), by wild Pedicellus et Pericarpium Trapae and Fructus Tritici Levis removing impurity, put into frying pan, big fire stir-fries to there being white cigarette to emerge, and takes out, and sieve removes Testa Tritici;
(4) by the Rhizoma Atractylodis Macrocephalae, Radix vignae sinensis, Caulis Stelmatocryptonis khasiani, Radix seu Folium Rubi Pinfaensis, Radix Caraganae intermediae, Radix Calystegiae sepii and the rinse of Radix Oryzae Glutinosae clear water, remove impurity is cut into slices, be placed in marmite, add boiled crude drug quality 6-8 water doubly (preferred: the water adding boiled crude drug quality 7 times), intense fire is heated to boiling, turn little fire to continue to decoct, collecting by filtration filtrate, and heating is concentrated into thick paste;
(5) made to step (1) (2) (3) crude drug is pulverized, mix with step (4) gained thick paste, be added into adjuvant, make granule, drying and packaging, obtain granule.
The preparation method of described preparation granules agent, the little fire of step (4) continues to decoct 22-34 minute (preferably: little fire continues to decoct 26-30 minute; Be more preferably: little fire continues decoction 28 minutes).
The preparation method of described preparation soft extract, step is as follows:
(1) get Radix Cynanchi Amplexicaulis, stone maple medicine, Herba Hyperici Sampsonii and Herba Bulbophylli inconspicui wash quickly clean, add yellow wine and soak 12-24 minute (preferably: soak 16-20 minute; Be more preferably: soak 18 minutes), take out and put into frying pan, the micro-stir-fry of slow fire is to dry, and taking-up cools;
(2) Fructus Corni and Mactraantiquata Spengler are cleaned pulverizing, add candy sugar powder mixing, the hydromel drenched into crude drug quality 1 times is mixed thoroughly, is placed in steamer, and Steam by water bath 15-25 minute (preferred: Steam by water bath 18-22 minute; Be more preferably: Steam by water bath 20 minutes), take out, drying is pulverized;
(3) getting Testa Tritici is placed in frying pan, adds rice vinegar and mixes moistening 8-18 minute thoroughly (preferably: mix moistening 10-16 minute thoroughly; Be more preferably: mix moistening thoroughly 13 minutes), by wild Pedicellus et Pericarpium Trapae and Fructus Tritici Levis removing impurity, put into frying pan, big fire stir-fries to there being white cigarette to emerge, and takes out, and sieve removes Testa Tritici;
(4) by the Rhizoma Atractylodis Macrocephalae, Radix vignae sinensis, Caulis Stelmatocryptonis khasiani, Radix seu Folium Rubi Pinfaensis, Radix Caraganae intermediae, Radix Calystegiae sepii and the rinse of Radix Oryzae Glutinosae clear water, remove impurity is cut into slices, be placed in marmite, add boiled crude drug quality 6-8 water doubly (preferred: the water adding boiled crude drug quality 7 times), intense fire is heated to boiling, turns little fiery continuation decoction 22-34 minute (preferred: little fire continuation decoction 26-30 minute; Be more preferably: little fire continues decoction 28 minutes), collecting by filtration filtrate;
(5) pulverized by made to step (1) (2) (3) crude drug, be added in step (4) gained filtrate, heating is concentrated into thick paste, obtains soft extract.
The preparation method of described preparation soft extract, it is (preferred: heating is concentrated into the thick paste that relative density is 1.10-1.14 that step (5) heating is concentrated into the thick paste (72 DEG C) that relative density is 1.08-1.16; Be more preferably: heating is concentrated into the thick paste that relative density is 1.12).
The preparation method of described preparation pill, step is as follows:
(1) get Radix Cynanchi Amplexicaulis, stone maple medicine, Herba Hyperici Sampsonii and Herba Bulbophylli inconspicui wash quickly clean, add yellow wine and soak 12-24 minute (preferably: soak 16-20 minute; Be more preferably: soak 18 minutes), take out and put into frying pan, the micro-stir-fry of slow fire is to dry, and taking-up cools;
(2) Fructus Corni and Mactraantiquata Spengler are cleaned pulverizing, add candy sugar powder mixing, the hydromel drenched into crude drug quality 1 times is mixed thoroughly, is placed in steamer, and Steam by water bath 15-25 minute (preferred: Steam by water bath 18-22 minute; Be more preferably: Steam by water bath 20 minutes), take out, drying is pulverized;
(3) getting Testa Tritici is placed in frying pan, adds rice vinegar and mixes moistening 8-18 minute thoroughly (preferably: mix moistening 10-16 minute thoroughly; Be more preferably: mix moistening thoroughly 13 minutes), by wild Pedicellus et Pericarpium Trapae and Fructus Tritici Levis removing impurity, put into frying pan, big fire stir-fries to there being white cigarette to emerge, and takes out, and sieve removes Testa Tritici;
(4) by the Rhizoma Atractylodis Macrocephalae, Radix vignae sinensis, Caulis Stelmatocryptonis khasiani, Radix seu Folium Rubi Pinfaensis, Radix Caraganae intermediae, Radix Calystegiae sepii and the rinse of Radix Oryzae Glutinosae clear water, remove impurity is cut into slices, be placed in marmite, add boiled crude drug quality 6-8 water doubly (preferred: the water adding boiled crude drug quality 7 times), intense fire is heated to boiling, turns little fiery continuation decoction 22-34 minute (preferred: little fire continuation decoction 26-30 minute; Be more preferably: little fire continues decoction 28 minutes), collecting by filtration filtrate;
(5) lyophilization step (4) gained filtrate, pulverizes and sieves dry thing, makes medicated powder together with step (1) (2) (3) made crude drug, adds that hydromel is general makes ball, dry packing, obtains pill.
The preparation method of described preparation pill, it is (preferred: to pulverize 80-120 mesh sieve that step (5) pulverized 60-140 mesh sieve; Be more preferably: pulverized 100 mesh sieves).
The preparation method of described preparation powder, step is as follows:
(1) get Radix Cynanchi Amplexicaulis, stone maple medicine, Herba Hyperici Sampsonii and Herba Bulbophylli inconspicui wash quickly clean, add yellow wine and soak 12-24 minute (preferably: soak 16-20 minute; Be more preferably: soak 18 minutes), take out and put into frying pan, the micro-stir-fry of slow fire is to dry, and taking-up cools;
(2) Fructus Corni and Mactraantiquata Spengler are cleaned pulverizing, add candy sugar powder mixing, the hydromel drenched into crude drug quality 1 times is mixed thoroughly, is placed in steamer, and Steam by water bath 15-25 minute (preferred: Steam by water bath 18-22 minute; Be more preferably: Steam by water bath 20 minutes), take out, drying is pulverized;
(3) getting Testa Tritici is placed in frying pan, adds rice vinegar and mixes moistening 8-18 minute thoroughly (preferably: mix moistening 10-16 minute thoroughly; Be more preferably: mix moistening thoroughly 13 minutes), by wild Pedicellus et Pericarpium Trapae and Fructus Tritici Levis removing impurity, put into frying pan, big fire stir-fries to there being white cigarette to emerge, and takes out, and sieve removes Testa Tritici;
(4) by the Rhizoma Atractylodis Macrocephalae, Radix vignae sinensis, Caulis Stelmatocryptonis khasiani, Radix seu Folium Rubi Pinfaensis, Radix Caraganae intermediae, Radix Calystegiae sepii and the rinse of Radix Oryzae Glutinosae clear water, remove impurity is cut into slices, be placed in marmite, add boiled crude drug quality 6-8 water doubly (preferred: the water adding boiled crude drug quality 7 times), intense fire is heated to boiling, turns little fiery continuation decoction 22-34 minute (preferred: little fire continuation decoction 26-30 minute; Be more preferably: little fire continues decoction 28 minutes), collecting by filtration filtrate;
(5) spray drying step (4) gained filtrate, pulverizes and sieves dry thing, makes medicated powder, obtain powder together with step (1) (2) (3) made crude drug.
The preparation method of described preparation powder, it is (preferred: to pulverize 200-220 mesh sieve that step (5) pulverized 160-260 mesh sieve; Be more preferably: pulverized 210 mesh sieves).
A kind of pharmaceutical formulation science of preventing and treating spontaneous perspiration provided by the invention, preparation method is simple.In addition, its excellent part also shows:
1, products obtained therefrom of the present invention, therapeutic effect is good, and cure rate is high, has no side effect for patient;
2, this formula is summed up through clinical practice for many years and is formed, and has effect of supplementing QI and nourishing YIN, liver and kidney tonifying;
3, Chinese crude drug selected by the present invention, wide material sources, cheap, do not increase patient economy burden.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
The Rhizoma Atractylodis Macrocephalae: nature and flavor with return through: bitter, sweet, temperature.Return spleen, stomach warp.Function with cure mainly: invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive.For insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.
Radix vignae sinensis: base is former: be the root of leguminous plant Semen vignae sinensis.Nature and flavor: sweet; Flat.Gui Jing: spleen; Stomach warp.Function cures mainly: invigorating the spleen and benefiting QI; Removing food stagnancy; Removing toxic substances.Main weakness of the spleen and stomach; Food stagnation; Leucorrhea; Stranguria with turbid discharge; Hemorrhoidal bleeding; Furuncle.
Radix Cynanchi Amplexicaulis: base is former: be root or the herb of asclepiadaceae plant Radix Cynanchi Amplexicaulis.Nature and flavor: bitter in the mouth; Pungent; Property is put down.Gui Jing: lung; Spleen channel.Function cures mainly: heat-clearing and toxic substances removing; Wind-damp dispelling; Promoting blood circulation and detumescence.Main air pain of dampness syndrome; Migraine; Lumbago; Menoxenia; Acute mastitis; Carbuncle furunculosis.
Stone maple medicine: base is former: be the herb of Rubiaceae plants of Hedyotis hedyotis tenelliflora Blume.The property of medicine: cold in nature, mildly bitter flavor is nontoxic.Function cures mainly: heat-clearing and toxic substances removing, promoting blood circulation and stopping pain.Cure mainly cough due to lung-heat, chronic hepatitis, tympanites, acute appendicitis, dysentery, acute toothache, infantile hernia, traumatic injury, venom.
Caulis Stelmatocryptonis khasiani: base is former: be the ratan of dicotyledon medicine asclepiadaceae plant Pentanura khasianum.Nature and flavor: Gan Xin; Temperature.Gui Jing: spleen; Stomach warp.Function cures mainly: expelling wind and cold; Promoting of the circulation of QI and removing the obstruction in the collaterals.Main flu; Cough; Abdominal distention; Anemofrigid-damp arthralgia.
Herba Hyperici Sampsonii: base is former: be the herb of Garcinia maingayii Herba Hyperici Sampsonii.Nature and flavor: bitter; Pungent; Cold.Gui Jing: liver; Spleen channel.Function cures mainly: cooling blood for hemostasis; Heat-clearing and toxic substances removing; Promoting blood flow to regulate menstruation; Passive wind and removing obstruction in channels.Main haematemesis; Spitting of blood; Epistaxis; Stranguria with blood; Menoxenia; Dysmenorrhea; Leucorrhea; Traumatic injury; Rheumatic arthralgia; Lumbago and skelalgia; External also can control tinea capitis; Aphtha; Corneal nebula.
Wild Pedicellus et Pericarpium Trapae: base is former: be the nut of the wild Pedicellus et Pericarpium Trapae of Trapaceae Pedicellus et Pericarpium Trapae platymiscium and Trapa maxinowiczii Korshinsky..The property of medicine: sweet, flat.Return taste warp.Function cures mainly: spleen reinforcing stomach invigorating, removing toxic substances and promoting subsidence of swelling.Cure mainly weakness of the spleen and stomach, have loose bowels, dysentery, alcoholism, skin ulcer swells.
Radix seu Folium Rubi Pinfaensis: base is former: be the root of the red hair Fructus Rubi corchorifolii Immaturus of rosaceous plant.Chemical analysis: root is containing 2a, 3 β, 23a-triacetoxyl group-19a-hydroxyl-12-Usu alkene-28 β acid-methyl ester.Nature and flavor: acid is salty; Cool.Gui Jing: liver; Kidney channel.Function cures mainly: cooling blood for hemostasis, expelling wind and removing dampness, detoxification sore treatment.Main heat in blood is spitted blood, and hematuria, has blood in stool, metrorrhagia, rheumatic arthritis, scrofula, eczema, leukorrhagia.
Radix Caraganae intermediae: base is former: be the root of leguminous plant Caragana intermedia.Nature and flavor: micro-pungent; Temperature.Gui Jing: the heart; Liver Channel.Function cures mainly: supplementing QI and nourishing YIN.Main dizziness, cardiopalmus, shortness of breath and fatigue, hypertension.
Fructus Corni: base is former: be the sarcocarp of Cornaceae plant Fructus Corni.Nature and flavor with return through: sour, puckery, tepor.Return liver, kidney channel.Have liver and kidney tonifying, effect of arresting collape syndrome by astringents, for dizzy ear toot, soreness of waist and knee joint, impotence and seminal emission, enuresis frequent micturition, bleeding not during menses, profuse sweating collapse, interior-heat is quenched one's thirst.
Mactraantiquata Spengler: base is former: be the meat of Carnis Mactrae section animal Mactraantiquata Spengler.Nature and flavor: sweet in the mouth; Salty; Property is put down.Gui Jing: Liver Channel.Function cures mainly: nourishing YIN and benefiting blood, the cool liver of heat clearing away.Main Liver and kidney clothes are empty; The acid of waist knee joint is heavy; Conjunctival congestion; Quench one's thirst.
Fructus Tritici Levis: base is former: the fruit of the frivolous lack of filling power of drying of grass family Triticum plant Semen Tritici aestivi.Gather during fruit maturation, get the wheat grain of the frivolous and non-peeling of lack of filling power, decontamination, sieve dedust bits, with water rinse, dry.Nature and flavor: sweet are cool.Function cures mainly: only sweating due to debility, tranquilizing by nourishing the heart.For the empty hyperhidrosis of body, hysteria.
Radix Calystegiae sepii: base is former: be the root of dicotyledon scammonia section plant bellbine.Nature and flavor: sweet; Micro-hardship; Temperature.Gui Jing: lung; Liver; Kidney channel.Function cures mainly: QI invigorating tonify deficiency; Reunion of fractured tendons and bones; Removing toxic substances; Parasite killing.Main erysipelas; Strain; Incised wound; Ascariasis.
Herba Bulbophylli inconspicui: base is former: be the herb of orchid Herba Bulbophylli inconspicui.Nature and flavor: sweet; Pungent; Cool; Nontoxic.Gui Jing: lung; Stomach warp.Function cures mainly: heat clearing away YIN nourishing; Nourishing the lung to arrest cough.Main cough due to lung-heat; Pulmonary tuberculosis is spat blood; Have sore throat; Calentura excessive thirst; Rheumatic arthralgia; Menoxenia; Traumatic injury.
Radix Oryzae Glutinosae: base is former: be rhizome and the root of grass rice (Oryza sativa L. var. glutinosa Matsum.).Nature and flavor: sweet are flat.Gui Jing: enter lung, kidney channel.Function cures mainly: replenishing YIN and removing heat, hidroschesis.Cure mainly fever due to yin deficiency, spontaneous sweating, thirsty and dry pharynx, hepatitis, filaricide.
embodiment 1prevent and treat a preparation for spontaneous perspiration, be prepared from (every part of 10g) primarily of following bulk drugs: the Rhizoma Atractylodis Macrocephalae 8 parts, Radix vignae sinensis 10 parts, Radix Cynanchi Amplexicaulis 9 parts, stone maple medicine 7 parts, Caulis Stelmatocryptonis khasiani 6 parts, Herba Hyperici Sampsonii 9 parts, wild Pedicellus et Pericarpium Trapae 7 parts, Radix seu Folium Rubi Pinfaensis 8 parts, Radix Caraganae intermediae 10 parts, Fructus Corni 8 parts, Mactraantiquata Spengler 6 parts, Fructus Tritici Levis 8 parts, Radix Calystegiae sepii 10 parts, Herba Bulbophylli inconspicui 9 parts, Radix Oryzae Glutinosae 7 parts.Above-mentioned a kind of preparation method of preventing and treating the preparation granules agent of spontaneous perspiration is:
(1) get Radix Cynanchi Amplexicaulis, stone maple medicine, Herba Hyperici Sampsonii and Herba Bulbophylli inconspicui wash quickly clean, add yellow wine and soak 18 minutes, take out and put into frying pan, the micro-stir-fry of slow fire is to dry, and taking-up cools;
(2) Fructus Corni and Mactraantiquata Spengler are cleaned pulverizing, add candy sugar powder mixing, the hydromel drenched into crude drug quality 1 times is mixed thoroughly, is placed in steamer, Steam by water bath 20 minutes, and take out, drying is pulverized;
(3) getting Testa Tritici is placed in frying pan, adds rice vinegar and mixes moistening thoroughly 13 minutes, and by wild Pedicellus et Pericarpium Trapae and Fructus Tritici Levis removing impurity, put into frying pan, big fire stir-fries to there being white cigarette to emerge, and takes out, and sieve removes Testa Tritici;
(4) by the Rhizoma Atractylodis Macrocephalae, Radix vignae sinensis, Caulis Stelmatocryptonis khasiani, Radix seu Folium Rubi Pinfaensis, Radix Caraganae intermediae, Radix Calystegiae sepii and the rinse of Radix Oryzae Glutinosae clear water, remove impurity is cut into slices, and is placed in marmite, add the water of boiled crude drug quality 7 times, intense fire is heated to boiling, turns little fire and continues decoction 28 minutes, collecting by filtration filtrate, and heating is concentrated into thick paste;
(5) made to step (1) (2) (3) crude drug is pulverized, mix with step (4) gained thick paste, be added into adjuvant, make granule, drying and packaging, obtain granule.
embodiment 2prevent and treat a preparation for spontaneous perspiration, be prepared from (every part of 10g) primarily of following bulk drugs: the Rhizoma Atractylodis Macrocephalae 12 parts, Radix vignae sinensis 14 parts, Radix Cynanchi Amplexicaulis 13 parts, stone maple medicine 12 parts, Caulis Stelmatocryptonis khasiani 13 parts, Herba Hyperici Sampsonii 14 parts, wild Pedicellus et Pericarpium Trapae 13 parts, Radix seu Folium Rubi Pinfaensis 14 parts, Radix Caraganae intermediae 15 parts, Fructus Corni 13 parts, Mactraantiquata Spengler 12 parts, Fructus Tritici Levis 15 parts, Radix Calystegiae sepii 16 parts, Herba Bulbophylli inconspicui 12 parts, Radix Oryzae Glutinosae 14 parts.Above-mentioned a kind of preparation method of preventing and treating the preparation soft extract of spontaneous perspiration is:
(1) get Radix Cynanchi Amplexicaulis, stone maple medicine, Herba Hyperici Sampsonii and Herba Bulbophylli inconspicui wash quickly clean, add yellow wine and soak 18 minutes, take out and put into frying pan, the micro-stir-fry of slow fire is to dry, and taking-up cools;
(2) Fructus Corni and Mactraantiquata Spengler are cleaned pulverizing, add candy sugar powder mixing, the hydromel drenched into crude drug quality 1 times is mixed thoroughly, is placed in steamer, Steam by water bath 20 minutes, and take out, drying is pulverized;
(3) getting Testa Tritici is placed in frying pan, adds rice vinegar and mixes moistening thoroughly 13 minutes, and by wild Pedicellus et Pericarpium Trapae and Fructus Tritici Levis removing impurity, put into frying pan, big fire stir-fries to there being white cigarette to emerge, and takes out, and sieve removes Testa Tritici;
(4) by the Rhizoma Atractylodis Macrocephalae, Radix vignae sinensis, Caulis Stelmatocryptonis khasiani, Radix seu Folium Rubi Pinfaensis, Radix Caraganae intermediae, Radix Calystegiae sepii and the rinse of Radix Oryzae Glutinosae clear water, remove impurity is cut into slices, and is placed in marmite, add the water of boiled crude drug quality 7 times, intense fire is heated to boiling, turns little fire and continues decoction 28 minutes, collecting by filtration filtrate;
(5) pulverized by made to step (1) (2) (3) crude drug, be added in step (4) gained filtrate, heating is concentrated into the thick paste (72 DEG C) that relative density is 1.12, obtains soft extract.
Model case: xxx, male, 38 years old.Medical history: patient occurred perspiring many before three months without obvious inducement, movable a little or tired postemphasis, lustreless complexion, spiritlessness and weakness, to examination in hospital, light red tongue, white and thin fur, deep-thready pulse and weak, be diagnosed as spontaneous perspiration.
Taking this example gained soft extract, each 6-10g, warm boiled water, one day twice, ten days is a course for the treatment of, and after patient takes one week, spontaneous perspiration remission, uncomfortable disease starts to eliminate, and after adhering to taking three courses for the treatment of, patient's energy strengthens, and the state of an illness is eliminated, recovery from illness.
embodiment 3prevent and treat a preparation for spontaneous perspiration, be prepared from (every part of 10g) primarily of following bulk drugs: the Rhizoma Atractylodis Macrocephalae 9 parts, Radix vignae sinensis 11 parts, Radix Cynanchi Amplexicaulis 10 parts, stone maple medicine 9 parts, Caulis Stelmatocryptonis khasiani 8 parts, Herba Hyperici Sampsonii 10 parts, wild Pedicellus et Pericarpium Trapae 8 parts, Radix seu Folium Rubi Pinfaensis 10 parts, Radix Caraganae intermediae 11 parts, Fructus Corni 9 parts, Mactraantiquata Spengler 8 parts, Fructus Tritici Levis 10 parts, Radix Calystegiae sepii 12 parts, Herba Bulbophylli inconspicui 10 parts, Radix Oryzae Glutinosae 9 parts.Above-mentioned a kind of preparation method of preventing and treating the preparation pill of spontaneous perspiration is:
(1) get Radix Cynanchi Amplexicaulis, stone maple medicine, Herba Hyperici Sampsonii and Herba Bulbophylli inconspicui wash quickly clean, add yellow wine and soak 18 minutes, take out and put into frying pan, the micro-stir-fry of slow fire is to dry, and taking-up cools;
(2) Fructus Corni and Mactraantiquata Spengler are cleaned pulverizing, add candy sugar powder mixing, the hydromel drenched into crude drug quality 1 times is mixed thoroughly, is placed in steamer, Steam by water bath 20 minutes, and take out, drying is pulverized;
(3) getting Testa Tritici is placed in frying pan, adds rice vinegar and mixes moistening thoroughly 13 minutes, and by wild Pedicellus et Pericarpium Trapae and Fructus Tritici Levis removing impurity, put into frying pan, big fire stir-fries to there being white cigarette to emerge, and takes out, and sieve removes Testa Tritici;
(4) by the Rhizoma Atractylodis Macrocephalae, Radix vignae sinensis, Caulis Stelmatocryptonis khasiani, Radix seu Folium Rubi Pinfaensis, Radix Caraganae intermediae, Radix Calystegiae sepii and the rinse of Radix Oryzae Glutinosae clear water, remove impurity is cut into slices, and is placed in marmite, add the water of boiled crude drug quality 7 times, intense fire is heated to boiling, turns little fire and continues decoction 28 minutes, collecting by filtration filtrate;
(5) lyophilization step (4) gained filtrate, pulverized 100 mesh sieves by dry thing, made medicated powder together with step (1) (2) (3) made crude drug, added that hydromel is general makes ball, dry packing, obtained pill.
Model case: xxx, women, 31 years old.Main suit: dynamic then perspire, fatigue and weakness; Medical history: after patient has given birth to baby, self-induction is perspired and is increased, and activity just goes out apogee sweating a little, and aversion to wind is afraid of cold, and be usually not good at speech, body void is weak, and to examination in hospital, pale tongue with white fur weak pulse, is diagnosed as spontaneous sweating due to deficientcy of blood.
Recommend to take this example gained pill, each 3-4 grain, warm boiled water through people, one day twice, within ten days, be a course for the treatment of, after patient takes a course for the treatment of, perspire and obviously reduce, body constitution strengthens, after adhering to taking two courses for the treatment of, patient's spontaneous perspiration is eliminated, and physical recovery is to normal, follow up a case by regular visits in half a year, do not recur again.
embodiment 4prevent and treat a preparation for spontaneous perspiration, be prepared from (every part of 10g) primarily of following bulk drugs: the Rhizoma Atractylodis Macrocephalae 11 parts, Radix vignae sinensis 13 parts, Radix Cynanchi Amplexicaulis 12 parts, stone maple medicine 10 parts, Caulis Stelmatocryptonis khasiani 11 parts, Herba Hyperici Sampsonii 13 parts, wild Pedicellus et Pericarpium Trapae 12 parts, Radix seu Folium Rubi Pinfaensis 12 parts, Radix Caraganae intermediae 14 parts, Fructus Corni 12 parts, Mactraantiquata Spengler 10 parts, Fructus Tritici Levis 13 parts, Radix Calystegiae sepii 14 parts, Herba Bulbophylli inconspicui 11 parts, Radix Oryzae Glutinosae 12 parts.Above-mentioned a kind of preparation method of preventing and treating the preparation powder of spontaneous perspiration is:
(1) get Radix Cynanchi Amplexicaulis, stone maple medicine, Herba Hyperici Sampsonii and Herba Bulbophylli inconspicui wash quickly clean, add yellow wine and soak 18 minutes, take out and put into frying pan, the micro-stir-fry of slow fire is to dry, and taking-up cools;
(2) Fructus Corni and Mactraantiquata Spengler are cleaned pulverizing, add candy sugar powder mixing, the hydromel drenched into crude drug quality 1 times is mixed thoroughly, is placed in steamer, Steam by water bath 20 minutes, and take out, drying is pulverized;
(3) getting Testa Tritici is placed in frying pan, adds rice vinegar and mixes moistening thoroughly 13 minutes, and by wild Pedicellus et Pericarpium Trapae and Fructus Tritici Levis removing impurity, put into frying pan, big fire stir-fries to there being white cigarette to emerge, and takes out, and sieve removes Testa Tritici;
(4) by the Rhizoma Atractylodis Macrocephalae, Radix vignae sinensis, Caulis Stelmatocryptonis khasiani, Radix seu Folium Rubi Pinfaensis, Radix Caraganae intermediae, Radix Calystegiae sepii and the rinse of Radix Oryzae Glutinosae clear water, remove impurity is cut into slices, and is placed in marmite, add the water of boiled crude drug quality 7 times, intense fire is heated to boiling, turns little fire and continues decoction 28 minutes, collecting by filtration filtrate;
(5) spray drying step (4) gained filtrate, pulverized 210 mesh sieves by dry thing, and made medicated powder, obtain powder together with step (1) (2) (3) made crude drug.
Model case: xxx, male, 42 years old.Medical history: patient is two months ago because of wind-engaging flu, and a month cold symptoms of taking medicine is eliminated substantially, and nearly first quarter moon comes, realize that health is perspired obviously, fear of cold is weak, and the mental status is poor, checks, be diagnosed as spontaneous perspiration through doctor.
Take this example gained powder, each 3-4g, warm boiled water, one day twice, within ten days, be a course for the treatment of, after patient takes a course for the treatment of, perspiration symptom is obviously alleviated, and muscle power strengthens, adhere to taking two courses for the treatment of, patient body recovers normal, and without other uncomfortable diseases, patient fully recovers.
embodiment 5prevent and treat a preparation for spontaneous perspiration, be prepared from (every part of 10g) primarily of following bulk drugs: the Rhizoma Atractylodis Macrocephalae 10 parts, Radix vignae sinensis 12 parts, Radix Cynanchi Amplexicaulis 11 parts, stone maple medicine 9.5 parts, Caulis Stelmatocryptonis khasiani 9.5 parts, Herba Hyperici Sampsonii 11.5 parts, wild Pedicellus et Pericarpium Trapae 10 parts, Radix seu Folium Rubi Pinfaensis 11 parts, Radix Caraganae intermediae 12.5 parts, Fructus Corni 10.5 parts, Mactraantiquata Spengler 9 parts, Fructus Tritici Levis 11.5 parts, Radix Calystegiae sepii 13 parts, Herba Bulbophylli inconspicui 10.5 parts, Radix Oryzae Glutinosae 10.5 parts.Above-mentioned a kind of preparation method of preventing and treating the preparation granules agent of spontaneous perspiration is:
(1) get Radix Cynanchi Amplexicaulis, stone maple medicine, Herba Hyperici Sampsonii and Herba Bulbophylli inconspicui wash quickly clean, add yellow wine and soak 18 minutes, take out and put into frying pan, the micro-stir-fry of slow fire is to dry, and taking-up cools;
(2) Fructus Corni and Mactraantiquata Spengler are cleaned pulverizing, add candy sugar powder mixing, the hydromel drenched into crude drug quality 1 times is mixed thoroughly, is placed in steamer, Steam by water bath 20 minutes, and take out, drying is pulverized;
(3) getting Testa Tritici is placed in frying pan, adds rice vinegar and mixes moistening thoroughly 13 minutes, and by wild Pedicellus et Pericarpium Trapae and Fructus Tritici Levis removing impurity, put into frying pan, big fire stir-fries to there being white cigarette to emerge, and takes out, and sieve removes Testa Tritici;
(4) by the Rhizoma Atractylodis Macrocephalae, Radix vignae sinensis, Caulis Stelmatocryptonis khasiani, Radix seu Folium Rubi Pinfaensis, Radix Caraganae intermediae, Radix Calystegiae sepii and the rinse of Radix Oryzae Glutinosae clear water, remove impurity is cut into slices, and is placed in marmite, add the water of boiled crude drug quality 7 times, intense fire is heated to boiling, turns little fire and continues decoction 28 minutes, collecting by filtration filtrate, and heating is concentrated into thick paste;
(5) made to step (1) (2) (3) crude drug is pulverized, mix with step (4) gained thick paste, be added into adjuvant, make granule, drying and packaging, obtain granule.
test example 1a kind of clinical practice preventing and treating the preparation (embodiment 5) of spontaneous perspiration of gained of the present invention:
Choose crowd: in June ,-2015 in May, 2014, according to medical case history, have patient 243 example of spontaneous perspiration symptom four hospitals' screenings, age 22-70 year, 37.5 ± 2.4 years old mean age, the course of disease 10 days-5 years, wherein male patient 128 example, female patient 115 example.All patients all meet the diagnostic criteria of spontaneous perspiration, and clinical symptoms shows as: perspiration and aversion to wind, dynamic then easily very easily to catch a cold, lustreless complexion, headache, white and thin fur, thready and weak pulse.
Before test, patient is divided into two groups at random, experimental group 130 example and matched group 113 routine, two groups in sex, age, the course of disease, the state of an illness etc. without significant difference.Experimental group takes products obtained therefrom of the present invention, each 3-4g, one day twice, warm boiled water, within ten days, is a course for the treatment of; Matched group takes other conventional medicines (XuHan-ting granule, YUPINGFENG KELI, astragalus membranaceous etc.).Period in a medicine carries out Continuous Observation to two groups of patients, record symptom and change.
Curative effect determinate standard: reference literature criterion of therapeutical effect, (1) cures: spontaneous perspiration is eliminated, and other uncomfortable diseases disappear; (2) take a turn for the better: sweating obviously reduces, other uncomfortable diseases are improved; (3) invalid: perspiration and other uncomfortable diseases have no significant change.Total effective rate=cure rate+improvement rate
Clinical effectiveness: after the taking medicine of two courses for the treatment of, the therapeutic outcome of two groups is as shown in table 1:
The healing patient of experimental group is 86 examples, and cure rate is 66.2%, and improvement patient is 41 examples, improvement rate is 31.5%, and total effective rate is 97.7%, and the total effective rate of matched group is 83.2%, be starkly lower than the therapeutic effect of experimental group, illustrate that products obtained therefrom of the present invention is evident in efficacy, cure rate is high.
The Rhizoma Atractylodis Macrocephalae of invigorating the spleen and benefiting QI, Radix vignae sinensis is had in the Chinese medicine used in the present invention, the Radix Cynanchi Amplexicaulis of heat-clearing and toxic substances removing, the stone maple medicine of promoting blood circulation and stopping pain, the Caulis Stelmatocryptonis khasiani of expelling wind and cold, the Herba Hyperici Sampsonii of promoting blood flow to regulate menstruation, the wild Pedicellus et Pericarpium Trapae of spleen reinforcing stomach invigorating, the Radix seu Folium Rubi Pinfaensis of cooling blood for hemostasis, the Radix Caraganae intermediae of supplementing QI and nourishing YIN, the Fructus Corni of liver and kidney tonifying, the Mactraantiquata Spengler of nourishing YIN and benefiting blood, the Fructus Tritici Levis of tranquilizing by nourishing the heart, the Radix Calystegiae sepii of QI invigorating tonify deficiency, the Herba Bulbophylli inconspicui of heat clearing away YIN nourishing, the Radix Oryzae Glutinosae of yin nourishing hidroschesis, multiple medical material synergism, play effect of supplementing QI and nourishing YIN, liver and kidney tonifying altogether, effectively eliminate spontaneous perspiration symptom.
It should be pointed out that detailed description of the invention is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clear and definite disclosed or according to undoubted the obtaining of the written description of file, the claimed scope of this patent all should be thought.
Claims (10)
1. prevent and treat a preparation for spontaneous perspiration, it is characterized in that, be prepared from primarily of following bulk drugs, be mass parts: Rhizoma Atractylodis Macrocephalae 8-12; Radix vignae sinensis 10-14; Radix Cynanchi Amplexicaulis 9-13; Stone maple medicine 7-12; Caulis Stelmatocryptonis khasiani 6-13; Herba Hyperici Sampsonii 9-14; Wild Pedicellus et Pericarpium Trapae 7-13; Radix seu Folium Rubi Pinfaensis 8-14; Radix Caraganae intermediae 10-15; Fructus Corni 8-13; Mactraantiquata Spengler 6-12; Fructus Tritici Levis 8-15; Radix Calystegiae sepii 10-16; Herba Bulbophylli inconspicui 9-12; Radix Oryzae Glutinosae 7-14.
2. a kind of preparation preventing and treating spontaneous perspiration as claimed in claim 1, is characterized in that, Rhizoma Atractylodis Macrocephalae 9-11; Radix vignae sinensis 11-13; Radix Cynanchi Amplexicaulis 10-12; Stone maple medicine 9-10; Caulis Stelmatocryptonis khasiani 8-11; Herba Hyperici Sampsonii 10-13; Wild Pedicellus et Pericarpium Trapae 8-12; Radix seu Folium Rubi Pinfaensis 10-12; Radix Caraganae intermediae 11-14; Fructus Corni 9-12; Mactraantiquata Spengler 8-10; Fructus Tritici Levis 10-13; Radix Calystegiae sepii 12-14; Herba Bulbophylli inconspicui 10-11; Radix Oryzae Glutinosae 9-12(is preferably: the Rhizoma Atractylodis Macrocephalae 10; Radix vignae sinensis 12; Radix Cynanchi Amplexicaulis 11; Stone maple medicine 9.5; Caulis Stelmatocryptonis khasiani 9.5; Herba Hyperici Sampsonii 11.5; Wild Pedicellus et Pericarpium Trapae 10; Radix seu Folium Rubi Pinfaensis 11; Radix Caraganae intermediae 12.5; Fructus Corni 10.5; Mactraantiquata Spengler 9; Fructus Tritici Levis 11.5; Radix Calystegiae sepii 13; Herba Bulbophylli inconspicui 10.5; Radix Oryzae Glutinosae 10.5).
3. the preparation method of the preparation granules agent as described in as arbitrary in claim 1-2, it is characterized in that, step is as follows:
(1) get Radix Cynanchi Amplexicaulis, stone maple medicine, Herba Hyperici Sampsonii and Herba Bulbophylli inconspicui wash quickly clean, add yellow wine and soak 12-24 minute (preferably: soak 16-20 minute; Be more preferably: soak 18 minutes), take out and put into frying pan, the micro-stir-fry of slow fire is to dry, and taking-up cools;
(2) Fructus Corni and Mactraantiquata Spengler are cleaned pulverizing, add candy sugar powder mixing, the hydromel drenched into crude drug quality 1 times is mixed thoroughly, is placed in steamer, and Steam by water bath 15-25 minute (preferred: Steam by water bath 18-22 minute; Be more preferably: Steam by water bath 20 minutes), take out, drying is pulverized;
(3) getting Testa Tritici is placed in frying pan, adds rice vinegar and mixes moistening 8-18 minute thoroughly (preferably: mix moistening 10-16 minute thoroughly; Be more preferably: mix moistening thoroughly 13 minutes), by wild Pedicellus et Pericarpium Trapae and Fructus Tritici Levis removing impurity, put into frying pan, big fire stir-fries to there being white cigarette to emerge, and takes out, and sieve removes Testa Tritici;
(4) by the Rhizoma Atractylodis Macrocephalae, Radix vignae sinensis, Caulis Stelmatocryptonis khasiani, Radix seu Folium Rubi Pinfaensis, Radix Caraganae intermediae, Radix Calystegiae sepii and the rinse of Radix Oryzae Glutinosae clear water, remove impurity is cut into slices, be placed in marmite, add boiled crude drug quality 6-8 water doubly (preferred: the water adding boiled crude drug quality 7 times), intense fire is heated to boiling, turn little fire to continue to decoct, collecting by filtration filtrate, and heating is concentrated into thick paste;
(5) made to step (1) (2) (3) crude drug is pulverized, mix with step (4) gained thick paste, be added into adjuvant, make granule, drying and packaging, obtain granule.
4. the preparation method of preparation granules agent as claimed in claim 3, is characterized in that, the little fire of step (4) continues to decoct 22-34 minute (preferably: little fire continues to decoct 26-30 minute; Be more preferably: little fire continues decoction 28 minutes).
5. the preparation method of the preparation soft extract as described in as arbitrary in claim 1-2, it is characterized in that, step is as follows:
(1) get Radix Cynanchi Amplexicaulis, stone maple medicine, Herba Hyperici Sampsonii and Herba Bulbophylli inconspicui wash quickly clean, add yellow wine and soak 12-24 minute (preferably: soak 16-20 minute; Be more preferably: soak 18 minutes), take out and put into frying pan, the micro-stir-fry of slow fire is to dry, and taking-up cools;
(2) Fructus Corni and Mactraantiquata Spengler are cleaned pulverizing, add candy sugar powder mixing, the hydromel drenched into crude drug quality 1 times is mixed thoroughly, is placed in steamer, and Steam by water bath 15-25 minute (preferred: Steam by water bath 18-22 minute; Be more preferably: Steam by water bath 20 minutes), take out, drying is pulverized;
(3) getting Testa Tritici is placed in frying pan, adds rice vinegar and mixes moistening 8-18 minute thoroughly (preferably: mix moistening 10-16 minute thoroughly; Be more preferably: mix moistening thoroughly 13 minutes), by wild Pedicellus et Pericarpium Trapae and Fructus Tritici Levis removing impurity, put into frying pan, big fire stir-fries to there being white cigarette to emerge, and takes out, and sieve removes Testa Tritici;
(4) by the Rhizoma Atractylodis Macrocephalae, Radix vignae sinensis, Caulis Stelmatocryptonis khasiani, Radix seu Folium Rubi Pinfaensis, Radix Caraganae intermediae, Radix Calystegiae sepii and the rinse of Radix Oryzae Glutinosae clear water, remove impurity is cut into slices, be placed in marmite, add boiled crude drug quality 6-8 water doubly (preferred: the water adding boiled crude drug quality 7 times), intense fire is heated to boiling, turns little fiery continuation decoction 22-34 minute (preferred: little fire continuation decoction 26-30 minute; Be more preferably: little fire continues decoction 28 minutes), collecting by filtration filtrate;
(5) pulverized by made to step (1) (2) (3) crude drug, be added in step (4) gained filtrate, heating is concentrated into thick paste, obtains soft extract.
6. the preparation method of preparation soft extract as claimed in claim 5, is characterized in that, it is (preferred: heating is concentrated into the thick paste that relative density is 1.10-1.14 that step (5) heating is concentrated into the thick paste that relative density is 1.08-1.16; Be more preferably: heating is concentrated into the thick paste that relative density is 1.12).
7. the preparation method of the preparation pill as described in as arbitrary in claim 1-2, it is characterized in that, step is as follows:
(1) get Radix Cynanchi Amplexicaulis, stone maple medicine, Herba Hyperici Sampsonii and Herba Bulbophylli inconspicui wash quickly clean, add yellow wine and soak 12-24 minute (preferably: soak 16-20 minute; Be more preferably: soak 18 minutes), take out and put into frying pan, the micro-stir-fry of slow fire is to dry, and taking-up cools;
(2) Fructus Corni and Mactraantiquata Spengler are cleaned pulverizing, add candy sugar powder mixing, the hydromel drenched into crude drug quality 1 times is mixed thoroughly, is placed in steamer, and Steam by water bath 15-25 minute (preferred: Steam by water bath 18-22 minute; Be more preferably: Steam by water bath 20 minutes), take out, drying is pulverized;
(3) getting Testa Tritici is placed in frying pan, adds rice vinegar and mixes moistening 8-18 minute thoroughly (preferably: mix moistening 10-16 minute thoroughly; Be more preferably: mix moistening thoroughly 13 minutes), by wild Pedicellus et Pericarpium Trapae and Fructus Tritici Levis removing impurity, put into frying pan, big fire stir-fries to there being white cigarette to emerge, and takes out, and sieve removes Testa Tritici;
(4) by the Rhizoma Atractylodis Macrocephalae, Radix vignae sinensis, Caulis Stelmatocryptonis khasiani, Radix seu Folium Rubi Pinfaensis, Radix Caraganae intermediae, Radix Calystegiae sepii and the rinse of Radix Oryzae Glutinosae clear water, remove impurity is cut into slices, be placed in marmite, add boiled crude drug quality 6-8 water doubly (preferred: the water adding boiled crude drug quality 7 times), intense fire is heated to boiling, turns little fiery continuation decoction 22-34 minute (preferred: little fire continuation decoction 26-30 minute; Be more preferably: little fire continues decoction 28 minutes), collecting by filtration filtrate;
(5) lyophilization step (4) gained filtrate, pulverizes and sieves dry thing, makes medicated powder together with step (1) (2) (3) made crude drug, adds that hydromel is general makes ball, dry packing, obtains pill.
8. the preparation method of preparation pill as claimed in claim 7, is characterized in that, it is (preferred: to pulverize 80-120 mesh sieve that step (5) pulverized 60-140 mesh sieve; Be more preferably: pulverized 100 mesh sieves).
9. the preparation method of the preparation powder as described in as arbitrary in claim 1-2, it is characterized in that, step is as follows:
(1) get Radix Cynanchi Amplexicaulis, stone maple medicine, Herba Hyperici Sampsonii and Herba Bulbophylli inconspicui wash quickly clean, add yellow wine and soak 12-24 minute (preferably: soak 16-20 minute; Be more preferably: soak 18 minutes), take out and put into frying pan, the micro-stir-fry of slow fire is to dry, and taking-up cools;
(2) Fructus Corni and Mactraantiquata Spengler are cleaned pulverizing, add candy sugar powder mixing, the hydromel drenched into crude drug quality 1 times is mixed thoroughly, is placed in steamer, and Steam by water bath 15-25 minute (preferred: Steam by water bath 18-22 minute; Be more preferably: Steam by water bath 20 minutes), take out, drying is pulverized;
(3) getting Testa Tritici is placed in frying pan, adds rice vinegar and mixes moistening 8-18 minute thoroughly (preferably: mix moistening 10-16 minute thoroughly; Be more preferably: mix moistening thoroughly 13 minutes), by wild Pedicellus et Pericarpium Trapae and Fructus Tritici Levis removing impurity, put into frying pan, big fire stir-fries to there being white cigarette to emerge, and takes out, and sieve removes Testa Tritici;
(4) by the Rhizoma Atractylodis Macrocephalae, Radix vignae sinensis, Caulis Stelmatocryptonis khasiani, Radix seu Folium Rubi Pinfaensis, Radix Caraganae intermediae, Radix Calystegiae sepii and the rinse of Radix Oryzae Glutinosae clear water, remove impurity is cut into slices, be placed in marmite, add boiled crude drug quality 6-8 water doubly (preferred: the water adding boiled crude drug quality 7 times), intense fire is heated to boiling, turns little fiery continuation decoction 22-34 minute (preferred: little fire continuation decoction 26-30 minute; Be more preferably: little fire continues decoction 28 minutes), collecting by filtration filtrate;
(5) spray drying step (4) gained filtrate, pulverizes and sieves dry thing, makes medicated powder, obtain powder together with step (1) (2) (3) made crude drug.
10. the preparation method of preparation powder as claimed in claim 9, is characterized in that, it is (preferred: to pulverize 200-220 mesh sieve that step (5) pulverized 160-260 mesh sieve; Be more preferably: pulverized 210 mesh sieves).
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100853829B1 (en) * | 2007-01-25 | 2008-08-22 | 김경수 | A functional soy-bean source for preventing hypertension and improving lipid metabolism and process for preparation thereof |
| CN101259224A (en) * | 2008-04-10 | 2008-09-10 | 北京万寿通医药科技有限公司 | Chinese medicine preparation for treating spontaneous perspiration and night sweating |
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2015
- 2015-10-20 CN CN201510678058.6A patent/CN105213838A/en not_active Withdrawn
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100853829B1 (en) * | 2007-01-25 | 2008-08-22 | 김경수 | A functional soy-bean source for preventing hypertension and improving lipid metabolism and process for preparation thereof |
| CN101259224A (en) * | 2008-04-10 | 2008-09-10 | 北京万寿通医药科技有限公司 | Chinese medicine preparation for treating spontaneous perspiration and night sweating |
Non-Patent Citations (1)
| Title |
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| 王勇: "汗证论治举隅", 《中国中医急症》 * |
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Address after: 756000 the Ningxia Hui Autonomous Region Yuanzhou District of Guyuan City Beihuan Limin District 2 Building 3 unit 601 Applicant after: Zhang Shiyuan Address before: 250000 Shandong, Ji'nan Flyover District Road, Tuen Mun, No. 12 Applicant before: Zhang Shiyuan |
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Application publication date: 20160106 |
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