CN105192195A - Anti-fatigue eleutherococcus senticosus health tea and preparation method thereof - Google Patents
Anti-fatigue eleutherococcus senticosus health tea and preparation method thereof Download PDFInfo
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Abstract
The invention provides anti-fatigue eleutherococcus senticosus health tea which comprises the following crude drugs in parts by weight: 10-50 parts of leaves of eleutherococcus senticosus, 10-20 parts of cortex lycii radicis, 10-20 parts of poria cocos, 10-20 parts of cortex albiziae, 10-20 parts of astragalus membranaceus, 10-20 parts of radix salviae miltiorrhizae, 10-20 parts of cornus officinalis, 10-20 parts of epimedium herb, 10-20 parts of mulberry,10-20 parts of schisandra chinensis, 10-20 parts of glossy privet fruit, 10-20 parts of semen cassiae, 10-20 parts of grassleaf sweelflag rhizome, 10-20 parts of cape jasmine fruit, 10-20 parts of polygonatum sibiricum and 10-20 parts of codonopsis pilosula. The eleutherococcus senticosus can boost spirit and physical vitality. The anti-fatigue eleutherococcus senticosus health tea has an anti-fatigue effect, enhances endurance and capacity and increases alert and learning ability. The anti-fatigue eleutherococcus senticosus health tea is a very satisfied health product for people recovered from illness, bearing excessive pressure or tension and working excessively, the crowd in poor health, caused by chronic diseases, and people requiring reaching the peak of physical and psychological performance.
Description
Technical field
The present invention relates to the health products containing deriving from plant composition, particularly a kind of acanthopanax root health tea and preparation method thereof of antifatigue.
Background technology
Present social pressures are large, and nervous rhythm makes people breathless.A lot of people complaint is worked hard, and the difficulty in lasting nervous, worried, working and learning, mental labour heavy for a long time, as with unhealthy emotion, very easily causes the sense of fatigue of health and body and mind then to cause neurasthenia, hypoimmunity.Neurasthenia is a kind of modal sacred disease.With confirmed fatigue, emotional lability, nerve dysfunction, being easy to excited and being easy to exhaustion is feature, and many with somatization and sleep-disorder as insomnia, headache, depression, notice lax, failure of memory and affective fragility, What is more can affect man and wife's normal life etc.Neurasthenia is not that single factors causes usually, but the health that unhealthy emotion experience, unsound personality feature and body function weaken coefficient result hypoimmunity is easy to infected or cancer stricken; Immunity is extraordinary also can produce insalubrious result, as caused allergic reaction, autoimmune disease etc.
A variety of causes makes immune system normally can not play protective effect, and in the case, very easily cause the infection such as bacterium, virus, fungi, therefore hypoimmunity the most directly shows is exactly liable to illness.Because of often ill, increased the weight of the consumption of body, thus generally have a delicate constitution, malnutritive, One's spirits are drooping, fatigue and weak, appetite reduction, the performance such as sleep-disorder, sick, have an injection and take medicine the normal potluck that just gets married.At every turn sickly all to could to recover for a long time, and usually recurrent exerbation.If things go on like this can cause health and intelligence development bad, also easily bring out major disease.
Day by day flourishing due to economy, the continuous lifting of modern's living standard, cause people too much have deep love for enjoy, do not notice that the life style of oneself, behavioural habits, diet are had a liking for, thus the disease caused.Society with fast rhythm lives, the operating pressure of keen competition, serious threat is caused to the physical and mental health of modern, add that long-term diet is unreasonable, that is: smart grain replaces coarse food grain completely, the agricultural chemicals remained in the absorption of a large amount of three height (high heat, high protein, higher fatty acid), more than three (anticorrisive agent is many, flavoring agent is many, hormone many) food and food, chemical fertilizer stockpiling in vivo, add air, pollution of waterhead and amount of exercise less than normal, obesity and diabetes have just become the rich man's disease of city gang.Work hard, the difficulty in lasting nervous, worried, working and learning, mental labour heavy for a long time, as with unhealthy emotion, more allows people feel dog-tired.
Wilsonii has another name called slender acanthopanax ginseng, and modern medicine research proves that its special efficacy is substantially identical with ginseng can improving water flood, raising sleep quality, treatment hypertension, high fat of blood, diabetes, cerebral thrombus, coronary heart disease antirheumatic, anti-ageing, antifatigue, strengthens immunologic function.
Modern medicine research proves that the action character of wilsonii is substantially identical with ginseng, has and regulates body disorderly, make it to be tending towards normal function.Have good antifatigue effect, comparatively ginseng is remarkable, and significantly can improve hypoxia-bearing capability.Bowl spares, benefit essence, strong will, wines used as antirheumatic, strengthen the bone, blood circulation and promoting silt, the function such as stomach invigorating diuresis.Clothes of a specified duration " are made light of one's life by commiting suicide and are endured hardships ".Wilsonii contains noticeable composition---and eleutheroside, it can stimulate mind & body vigor.Numerous scientific publications about wilsonii demonstrates its antifatigue effect, strengthens endurance and ability, increases alert and resourceful and learning ability.Numerous usage obtains confirmation all in human experimentation.Wilsonii is rehabilitation after being ill, bears too much pressure or anxiety, works excessive, chronic disease cause weakly crowd and those need to reach very welcome self-medication medicine in the people on physiology and psychological performance peak.It has support immune system to have the report of considerable quantity to point out, recovers improper low blood pressure, improves the circulatory system, makes disorderly glycolipid metabolism normalization, liver, testis, anabolic effect of bone density and other vitals.
Does the tea that wilsonii is made have what effect and effect? radix Acanthopanacis senticosi tea is containing multiple glucoside, wherein part glucoside and panaxoside have similar physiologically active, there is antifatigue (antifatigue effect of eleutheroside is also stronger than ginseng), add essence benefit marrow and anti-ageing, soothing nerves and assisting sleep dormancy effect of fostering the spirit of nobility, being the useful health drink of drink, is the first-class natural beverage of the elderly and presenting friends.Effect of radix Acanthopanacis senticosi tea in ancient times just known by people, effect that " Mingyi Bielu " describes wilsonii to be had " bowl spares benefit essence, hard muscles and bones, strong will ".Therefore ancients have saying of " Ning get Yi, slender acanthopanax, not wanting the full car of gold and jade "; Wilsonii sees Shennong's Herbal, is classified as top grade; Top grade is refer to nontoxic, and for a long time clothes can be made light of one's life by commiting suicide, to be promoted longevity and harmless.Therefore radix Acanthopanacis senticosi tea also can as daily drink, can Long-Time Service.
The various health products sold on the market now, dragons and fishes jumbled together for medicine, and the amusement of great majority just false propaganda, what have does not only have health-care components, also causes the huge injury of the person.Chinese medicine odor is poor, and a lot of people is reluctant long-term taking; Even if take, be medicine three points of poison, allow during people's long-term taking and also produce resisting psychology.How the efficacy exertion of wilsonii not being injured human body again to maximum, and obviously improve mouthfeel, people can be accepted, is our problem in the urgent need to address.
Summary of the invention
Technical problem to be solved by this invention is, the various health products sold on the market now, dragons and fishes jumbled together for medicine, and the amusement of great majority just false propaganda, what have does not only have health-care components, also causes the huge injury of the person.Chinese medicine odor is poor, and a lot of people is reluctant long-term taking; Even if take, be medicine three points of poison, allow during people's long-term taking and also produce resisting psychology.Modern's fitness is poor, does not like motion, and dynamic then pant, spontaneous perspiration is afraid of cold, dizzy tinnitus, and soreness and weakness of waist and knees, breathes hard, lassitude hypodynamia, oliguria edema, and tongue is light, greasy and thin fur, weak pulse or moisten.For the ubiquitous sub-health state of working clan, susceptible is tired, be probably difficult to adhere to, and trouble is taken by Chinese medicine if simple by drug therapy, unsuitable long-term taking, and effect is also not necessarily desirable.
For solving above-mentioned technical barrier, the invention provides a kind of acanthopanax root health tea of antifatigue, acanthopanax root health tea described in it comprises the bulk drug of following parts by weight: acanthopanax 10 ~ 50 parts, the root bark of Chinese wolf-berry 10 ~ 20 parts, 10 ~ 20 parts, Poria cocos, cortex albiziae 10 ~ 20 parts, the Radix Astragali 10 ~ 20 parts, the red sage root 10 ~ 20 parts, Fructus Corni 10 ~ 20 parts, barrenwort 10 ~ 20 parts, mulberries 10 ~ 20 parts, 10 ~ 20 parts, the fruit of Chinese magnoliavine, the fruit of glossy privet 10 ~ 20 parts, cassia seed 10 ~ 20 parts, grass-leaved sweetflag 10 ~ 20 parts, cape jasmine 10 ~ 20 parts, sealwort 10 ~ 20 parts, Radix Codonopsis 10 ~ 20 parts.
The acanthopanax root health tea of described antifatigue, the bulk drug of following parts by weight can be comprised: acanthopanax 10 ~ 30 parts in acanthopanax root health tea described in it, the root bark of Chinese wolf-berry 10 ~ 15 parts, 10 ~ 15 parts, Poria cocos, cortex albiziae 10 ~ 15 parts, the Radix Astragali 10 ~ 15 parts, the red sage root 10 ~ 15 parts, Fructus Corni 10 ~ 15 parts, barrenwort 10 ~ 15 parts, mulberries 10 ~ 20 parts, 10 ~ 20 parts, the fruit of Chinese magnoliavine, the fruit of glossy privet 10 ~ 20 parts, cassia seed 10 ~ 20 parts, grass-leaved sweetflag 10 ~ 20 parts, cape jasmine 10 ~ 20 parts, sealwort 10 ~ 20 parts, Radix Codonopsis 10 ~ 20 parts.
The acanthopanax root health tea of described antifatigue, the bulk drug of following parts by weight can also be comprised: acanthopanax 10 ~ 40 parts in acanthopanax root health tea described in it, the root bark of Chinese wolf-berry 10 ~ 20 parts, fuling peel 10 ~ 20 parts, cortex albiziae 10 ~ 20 parts, the Radix Astragali 10 ~ 20 parts, the red sage root 10 ~ 20 parts, Fructus Corni 10 ~ 20 parts, barrenwort 10 ~ 20 parts, mulberries 10 ~ 15 parts, 10 ~ 15 parts, the fruit of Chinese magnoliavine, the fruit of glossy privet 10 ~ 15 parts, cassia seed 10 ~ 15 parts, grass-leaved sweetflag 10 ~ 15 parts, cape jasmine 10 ~ 15 parts, sealwort 10 ~ 15 parts, Radix Codonopsis 10 ~ 15 parts.
For solving the problems of the technologies described above, the present invention also provides a kind of preparation method of acanthopanax root health tea of antifatigue, and described in it, the preparation process of acanthopanax root health tea comprises following aspect:
A. first the acanthopanax plucked is cleaned and dry, then put into roller fixation machine and complete;
B. the electric frying pan put into by acanthopanax after terminating that completes stir-fries shaping;
C. shaping acanthopanax is put into and is carried camera Titian;
D. all the other bulk drugs described are prepared into granule or pulvis,
E. by the acanthopanax prepared and the granule obtained or pulvis mixing, pack shaping.
In described step a, can pluck wilsonii tender leaf spring every year, first the free of contamination acanthopanax of anosis worm plucked be put into water and rinse, after taking out, airing is on ventilative bamboo mat, and upset airing 7-12 hours, parches collection; The acanthopanax that airing is good is put into roller fixation device complete, complete 20-40 minute at 80-100 DEG C.
In described step b, naturally dry in the shade after the acanthopanax after completing can being taken out, put into large iron pan and knead, knead on first backward downwards, firmly want evenly, when filament leaf bar rope is comparatively tight, the baking machine turning in putting into 50-60 DEG C when becoming dark brown fry 30-45 minute shaping.
In described step c, the acanthopanax stir-fried can be dried naturally, put into fragrance extracting machine Titian 30-40 minute, temperature controls in 50-60 DEG C, naturally dries after taking out.
In described steps d, the preparation method making granule when all the other bulk drugs is, surplus stock medicine component is put into the ethanol accounting for its quality 10 times amount, heating and refluxing extraction 2 times, each 1-2 hour, remove supernatant, merge extract, 100-110 order filters, be the ultrafiltration post ultrafiltration of 6000-10000 again through the molecular weight that dams, when ultrafiltrate reduced pressure concentration relative density is 80 DEG C 1.36 medicinal extract, heating be concentrated into paste, stand for standby use; The dregs of a decoction of the component bulk drug medicinal material crossed by above-mentioned alcohol extract again add the water heating and refluxing extraction 2 times accounting for its quality 10 times amount, remove supernatant, merge extract, 100-110 order filters, be the ultrafiltration post ultrafiltration of 6000-10000 again through the molecular weight that dams, when ultrafiltrate reduced pressure concentration relative density is 80 DEG C 1.36 medicinal extract, heating be concentrated into paste, stand for standby use; Extract medicinal extract by above-mentioned two kinds to merge, reducing pressure after reclaiming ethanol, it is concentrated to put into inspissator, by gained concentrate adjustment proportion to 1.40; reduce pressure to obtain medicinal extract; put into dryer to dry, then add honey or dextrin mediation, put into the granule that granulator makes 0.1-0.2 centimetre.
In described steps d, can also be, preparation method when all the other bulk drugs make pulvis is: mixed by described parts by weight by all the other bulk drug medicines described, shredded 100 ~ 120 mesh sieves, after sieving, fine powder is for subsequent use, and coarse granule puts into acid and alkali-resistance infusion kettle, at room temperature, flood 10 ~ 15 days together with more than 70 degree ethanol, the liquid flooded and the dregs of a decoction are carried out squeeze and filter, after separation, gets filtrate; Described filtrate heating is concentrated into pasty state, puts into drying in oven, after cooling, grind to form fine powder; Add the fine powder obtained sieved, be mixed into pulvis.
In described step e, will obtain granule or pulvis mixes with the acanthopanax that above-mentioned steps makes in steps d, after ultraviolet sterilization, pack packaging is shaping.
The technique effect that the present invention is useful is, radix Acanthopanacis senticosi tea is containing multiple glucoside, wherein part glucoside and panaxoside have similar physiologically active, there is antifatigue (antifatigue effect of eleutheroside is also stronger than ginseng), add essence benefit marrow and anti-ageing, soothing nerves and assisting sleep dormancy effect of fostering the spirit of nobility, being the useful health drink of drink, is the first-class natural beverage of the elderly and presenting friends.Effect of radix Acanthopanacis senticosi tea in ancient times just known by people, effect that " Mingyi Bielu " describes wilsonii to be had " bowl spares benefit essence, hard muscles and bones, strong will ".Wilsonii sees Shennong's Herbal, is classified as top grade; Top grade is refer to nontoxic, and for a long time clothes can be made light of one's life by commiting suicide, to be promoted longevity and harmless.Therefore radix Acanthopanacis senticosi tea also can as daily drink, can Long-Time Service.The present invention has antifatigue effect, strengthens endurance and ability, increases alert and resourceful and learning ability.The present invention is rehabilitation after being ill, bears too much pressure or anxiety, works excessive, chronic disease cause weakly crowd and those need the very satisfied health products of the people reaching physiology and psychological performance peak.
Detailed description of the invention
Human immunity is the defensive enginery of human body pathogenic microorganism to external world etc., or perhaps system of defense, and under normal circumstances, it can ensure human body not by the infringement of extraneous pathogenic microorganism.The body immunity of usual theory just refers to that the immune system of human body resists the ability of the infringements such as exotic disease pathogenic microorganism.In the normal situation of body immunity, human body self can resist the infringement of considerable germ, avoids causing damage to human body.Immunity plays an important role in human life mechanism, and the nutrition of human body, fatigue, mood, environment, disease, medication, radiation etc. cause the immunity degradation of self.More and more research shows, the adjustment of Chinese medicine to body immunity more and more plays a significant role.
The health-care effect of Chinese medicine is very strong, if Western medicine easily causes health to occur a large amount of side effect, make people occur bad reaction, the little effect with taking for a long time of toxic and side effect of that Chinese medicine is more obvious.
Modern medicine research proves that the action character of wilsonii is substantially identical with ginseng, has and regulates body disorderly, make it to be tending towards normal function.Have good antifatigue effect, comparatively ginseng is remarkable, and significantly can improve hypoxia-bearing capability.Bowl spares, benefit essence, strong will, wines used as antirheumatic, strengthen the bone, blood circulation and promoting silt, the function such as stomach invigorating diuresis.Clothes of a specified duration " are made light of one's life by commiting suicide and are endured hardships ".Wilsonii contains noticeable composition---and eleutheroside, it can stimulate mind & body vigor.Numerous scientific publications about wilsonii demonstrates its antifatigue effect, strengthens endurance and ability, increases alert and resourceful and learning ability.Numerous usage obtains confirmation all in human experimentation.Wilsonii is rehabilitation after being ill, bears too much pressure or anxiety, works excessive, chronic disease cause weakly crowd and those need to reach very welcome self-medication medicine in the people on physiology and psychological performance peak.It has support immune system to have the report of considerable quantity to point out, recovers improper low blood pressure, improves the circulatory system, makes disorderly glycolipid metabolism normalization, liver, testis, anabolic effect of bone density and other vitals.
Effect on central nervous system: wilsonii all has impact to the excitement of nervous centralis and process of inhibition, independent 1 administration demonstrates the spread effect of central nervous system, and successive administration then demonstrates strong effect.Wilsonii not only improves excited process, and strengthens process of inhibition, makes suppression be tending towards concentrated, makes differentiation more complete, increases corticocerebral process of intercentral inhibition.Its excitation principle is different from the compound of amphetamine, and not only toxicity is low, and does not upset normal sleep, and wilsonii quite has relation to neural functional status when neural excitement or suppression and medication and dosage size.
Antifatigue effect: extract and the glucoside of Radix Acanthopanacis Senticosi root all have antifatigue effect.The effect of glucoside comparatively phase extract is strong, and comparatively ginseng extract and panaquilon are strong.Lumbar injection wilsonii alcohol medicinal extract aqueous solution 20g/kg, average prolongation mouse swimming time 1/4.Caulis Et Caulis Acanthopanacis Senticosi severe edema due to hypofunction of the spleen extract 500mg/kg and syringaresinol-two-o-B-D-glycoside 50mg/kg thereof all can significant prolongation rat load swimming time.With the physiologically active of mouse rope climbing test determination Radix Acanthopanacis Senticosi root at different growing stage, display: the dry root of 1g in May is 79SUA33/g (excitation unit), July, active obviously decline, can reach maximum 116SUA33/g to August before fallen leaves.Acanthopanax also shows similar change (SUA33: animal used as test is compared with control-animal, the dosage delaying during exhaustion 33% is 1 SUA33).The extract of Radix Acanthopanacis Senticosi root and leaf can improve activities in rats energy 25% and 70% respectively.
The red sage root is bitter, is slightly cold.The thoughts of returning home, Liver Channel.Stasis-dispelling and pain-killing, activating blood to promote menstruation, clear away heart-fire relieving restlessness.For irregular menstruation, through closing dysmenorrhoea, a lump in the abdomen causing distension and pain, and chest ventral spine pain, hot numbness pain, sore swells and ache, dysphoria and insomnia.For sternal rib hypochondriac pain, arthralgia due to wind-dampness, abdominal mass lumps, and sore swells and ache, fall fall forward grieved, irregular menstruation, through closing dysmenorrhoea, postpartum stasis of blood pain etc.Treatment sternal rib pain, abdominal mass caking, and irregular menstruation, through amenorrhoea pain, there is good effect." detailed outline " carries: the red sage root, and by " the sensible opinion of married woman " cloud, gynecopathy controlled by Siwu Tang, pays no attention to antenatal postpartum, how many through water, all can be general, and the only taste red sage root falls apart, and cures mainly identical with it.The lid red sage root can break place blood, mends new blood, peaceful tire, and fall stillborn foetus, only metrorrhagia stagnant under, menstruation regulating arteries and veins.Main Compositions of Radix Salviae Miltiorrhizae tanshinone has hemangiectasis, improves circulation, removes the effects such as intravascular coagulation, has effect of invigorating blood circulation trace, and can promote that liver blood circulates, be beneficial to liver cell regeneration.
Fructus Corni enters liver, spleen, three burnt three warps.Function cures mainly activating QI to alleviate the depression, and method wind-dryness is wet, promoting blood circulation and stopping pain.Controlling air-cooled headache revolves dizzy, hypochondriac pain abdomen ache, arthritis muscle contraction, through closing, difficult labour, postpartum stasis blocking block pain, ulcer sores.For irregular menstruation, through closing dysmenorrhoea, lump in the abdomen is suffered from abdominal pain, the shouting pain of the chest side of body, tumbling and swelling, headache, arthralgia due to wind-dampness." detailed outline " carries: " eliminating dampness, antidiarrheal dysentery, activating QI to alleviate the depression." Fructus Corni piperazine removes vascular smooth muscle (aortic article) spasm (adrenaline, potassium chloride cause).Can also coronary vasodilator be expanded, increase CF.The myocardial ischemia-anoxemia that antagonism pituitrin causes.Alleviate the myocardial infarction lesion degree that ligation coronary artery causes.
The fruit of Chinese magnoliavine contains abundant organic acid, vitamin, flavonoids, phytosterol and has the lignan of potent reactivation (such as schizandrin, deoxyschizandrin or fruit of Chinese magnoliavine fat element), it is also one of the minority medicinal material having essence, gas, god's three large helps concurrently, can the strong liver of beneficial gas, the efficiency of promoting cells exclude refuse, supply more oxygen, construction and utilization energy, raising memory and property endurance.In ancient times, Russian hunter must take the fruit of Chinese magnoliavine to keep fit tonifying Qi at every turn before going on a long journey hunting.The fruit of Chinese magnoliavine has outstanding effect, comprising: 1, protect the liver and regenerate liver organization.Liver is the maincenter removing toxic substances organ of human body, is responsible for filtering noxious material, in order to avoid damage human body.The fruit of Chinese magnoliavine has antiinflammation, the fruit of Chinese magnoliavine has antiinflammation, to prevent hepar damnification, activates anabolic process to promote the reparation of wounded hepatocytes, and the activity of DNA (DNA) synthetic and ornithine decarboxylase can be strengthened, regeneration liver cell.Carbon tetrachloride (CCl4) be wherein a kind of to liver most poison material.Countless research displays, the potent liver-protecting efficacy of the fruit of Chinese magnoliavine can resist the toxic action of CCl4.As can be seen here, the fruit of Chinese magnoliavine has very large effect at protection liver from daily toxin infringement.
Barrenwort is pungent, sweet, warm, returns liver, kidney channel.Can tonify the kidney and support yang, strengthening the muscles and bones, dispels rheumatism, and is apt to control the insufficiency of the kidney yang, impotence and seminal emission, enuresis frequent micturition; Arthralgia due to wind-dampness, atrophic debility of bones paralysis disease." excessive sheep is fiery, and the main impotence of " herbal classic " medicine is hindered absolutely, and " solar corona " also its treatment of first speech man is positive absolutely, and woman is cloudy absolutely, then calling into the gate of vitality, benefit kidney-Yang person is also for " book on Chinese herbal medicine is stated " cloud.The lid gate of vitality be kidney-Yang in kidney, and namely the vigour of the person is also, its so-called exhausted yang exhaustion the moon, the not vigour of basis, how hiss in both withered.So-called beneficial strength, Qiang Zhi, and control cold air labor gas, muscles and bones contraction is anxious waits card, and all it helps the event of vigour.Old man dusk octogenarian, middle age forgetful, all Yuanyang decay and can not ascensionist also.Must know that this taste is to reduce to liter, it rises.
The dry mature seed that cassia seed (formal name used at school: CatsiatoraLinn) is pulse family annual herb plant Cassia tora or little Cassia tora.Cassia seed is also Cassia occidentalis.Cassia seed is annual suffruticose draft; The brightly yellowish look of Cassia tora, pod is elongated, four prism type; Little Cassia tora plant is less, and pod is shorter, is one of important composition.Have the merit of improving eyesight fat-reducing with it and name it.Cassia seed bitter, sweet, salty, cold nature, enters liver, kidney, large intestine channel; Relax bowel, lipopenicillinase improving eyesight, treatment constipation and high fat of blood, hypertension.Clear liver and improve vision, sharp water defaecation, has laxative action, reducing blood pressure and blood fat.
Mulberries nourishing yin and nourishing blood medicine; Promote the production of body fluid medicine; Aperitive.To enrich blood enriching yin, promote the production of body fluid and moisturize.For dizzy tinnitus, palpitation and insomnia, poliosis, Tianjin wound is thirsty, and interior heat is quenched one's thirst, blood deficiency and constipation.Tonifying liver, kidney-nourishing, relieves dizziness, high fever, infantile convulsions, epilepsy, etc., and grows liquid.Control liver-kidney Yin deficiency, quench one's thirst, constipation, order is dark, tinnitus, scrofula, articular instability.Both can food, can be used as medicine again, the traditional Chinese medical science thinks the sweet acid of mulberries taste, and cold nature, enters the heart, liver, kidney channel, is strengthening by means of tonics, the good fruit of intelligence development of nourishing heart.There is enriching yin of enriching blood, promote the production of body fluid to quench thirst, the effects such as ease constipation is dry, cure mainly deficiency of YIN-blood and having a dizzy spell of causing, tinnitus palpitaition, irritated insomnia, soreness and weakness of waist and knees, poliosis, dry of quenching one's thirst, the diseases such as dry and hard excrement.
The root bark of Chinese wolf-berry is cold in nature, and taste is sweet.Function cures mainly: cool blood is except steaming, and fire falls in clearing lung-heat.For deficiency of Yin hectic fever, hectic fever due to yin night sweat, cough with lung heat, spitting of blood, bleeding from five sense organs or subcutaneous tissue.Heat-clearing, cool blood.Control consumptive disease hectic fever night sweat, lung heat is coughed and is breathed heavily, and spits blood, bleeding from five sense organs or subcutaneous tissue, and blood drenches, and quenches one's thirst, hypertension, and carbuncle swells, and dislikes sore." herbal classic ": " perverse trend in main five, hankers quenching one's thirst, general arthralgia." " not Lu ": " main air wets, lower breast side of body gas, the headache of visitor's heat, mends internal injury great Lao and to hiss suction, hard muscle, reinforcing yin essence, sharp intestine and small intestine, resistance to cold and heat." " property of medicine opinion ": " smooth file, face is mixed and is well-donely gulped down it, cures mainly kidney family tradition." " dietetic materia medica ": " heat of boning is quenched one's thirst."
Cortex albiziae is the dry bark of pulse family (Legumin0sae) plant silk tree, in curling tubular or half tubular, and long 40 ~ 80cm, thick cortex albiziae 0.1 ~ 0.3cm.Outer surface taupe brown is to taupe, and nature and flavor are sweet, flat.There is the merit of Xie Yu and blood, Ning Xin, subduing inflammation.Have and control that confused and worried, melancholy, insomnia, lung carbuncle, carbuncle are swollen, the effect of scrofula, injured bone.
Poria cocos taste is sweet, light, property is put down, and is used as medicine and has the function of clearing damp and promoting diuresis, beneficial spleen and stomach, antitoxic heart-soothing and sedative.Nature and flavor are sweet, light flat.There are the functions such as excreting dampness, invigorating the spleen, Ning Xin.For phlegm and retained fluid, oedema, difficult urination, have loose bowels, palpitaition, dizzy.Fuling peel, inducing diuresis for removing edema, the diseases such as the edema that wets for water, for palpitation with fear of having a guilty conscience, forgetful, insomnia, frightened epilepsy, difficult urination." not Lu ": treat wind dizzy, wind be empty, the exhaustion or lesion of the five internal organs, dry.Only palpitation with fear, is enraged more, forgetful.Happy intelligence development, supports spirit.
The Radix Astragali is the pure natural product that the common people often eat, the jingle that folklore " often drinking astragali seu Hedysari Decoction, disease-prevention health health ", mean through the conventional Radix Astragali with the precious glossy ganoderma of fine jade decoct soup or soaked generation tea-drinking, there is good disease-prevention health effect.The Radix Astragali and ginseng all belong to tonifying Qi good medicine, and ginseng biases toward and reinforces vital energy, recuperating depleted yang, and be usually used in the acute diseases such as collapse, shock, effect is better.The Radix Astragali, then based on qi-restoratives, is usually used in that with the passing of time body declines, speech is low, small and weak pulse person.Some people is easy to catch cold once meeting Changes in weather, and the traditional Chinese medical science is called " table is not solid ", and admittedly can show with the Radix Astragali, the informal dress Radix Astragali can avoid regular flu.Modern medicine study shows, the Radix Astragali has enhanced machine body immunity function, protects the liver, diuresis, anti-ageing, resisting stress, step-down and antibacterial action more widely.Jishengshenqiwan albuminuria can be eliminated, strengthen myocardial contractive power, regulate blood-sugar content.The Radix Astragali can not only coronary artery dilator, improves myocardial blood supply, improves immunologic function, and can the process of delaying cell aging.Radix Astragali instant, can decoct soup, soft extracts, infusing drugs in wine, enter dish etc.
Radix Codonopsis taste is sweet, and property is put down.The effect having tonifying middle-Jiao and Qi, promote the production of body fluid to quench thirst, nourish blood and seek, be usually used in spleen-lung Qi deficiency, sound is humble, lazy speech is losed heart, weakness of limbs, be off one's feed, the deficiency of vital energy, gas Tianjin two are empty, qi and blood is two loses and the disease such as the deficiency of blood is sallow.But illness that has not attacked the vital organs of the human body do not separate and in can not the using of the full domination of pathogen.
The fruit of glossy privet, sweet-bitter flavor, cool in nature, return liver kidney channel, there is the merit that nourishing liver and kidney, beneficial the moon nourishes blood.Modern medicine study proves, the fruit of glossy privet includes ursolic acid, sweet mellow wine, glucose, fatty wet goods, has cardiac stimulant, diuresis and hepatoprotective effect, the leucocyte decline quantity caused because of chemotherapy can be made to raise, and have inhibitory action to staphylococcus aureus, Escherichia coli.The acid of the oleanolic acid fruit of glossy privet, Ligustrum lucidum Ait, ursolic acid, stearic acid, oleic acid, sweet mellow wine, betulin, phosphatide and carbohydrate is contained as Fructus Ligustri Lucidi polysaccharide, arabinose, glucose etc. in the fruit of glossy privet, also containing 15 seed amino acids, 11 kinds of trace elements and volatilization wet goods.Research thinks that the fruit of glossy privet has hypoglycemic and reducing blood lipid and has study of anti-atherogenic effect, and antibacterial, antivirus action in addition, fruit of glossy privet decoction all has inhibitory action to staphylococcus aureus, shigella flexneri, typhoid bacillus, Pseudomonas aeruginosa and Escherichia coli.
Grass-leaved sweetflag dampness elimination is whetted the appetite, open-minded phlegm of having one's ideas straightened out, inducing resuscitation intelligence development.Not hungry for gastral cavity ruffian, a mouthful diarrhea of keeping silent, coma epilepsy, forgetful deafness.Regulate the flow of vital energy, invigorate blood circulation, loose wind, dries.Control epilepsy, coma due to blocking of the respiratory system, pyreticosis coma, forgetful, deafness with qi stagnation, ambition is unhappy, stomachache, stomachache, wind-cold-dampness arthralgia, swollen ulcer drug, traumatic injury.
Cape jasmine is bitter, cold.The thoughts of returning home, lung, tri-jiao channel.For pyreticosis heating, vexed not rather wait disease.Cape jasmine is kind can expel the heat-evil and relieving restlessness in purging intense heat.Divide the disease initial stage at the gas of fever caused by exogenous pathogenic factors, see have heating, the disease such as uncomfortable in chest, vexed, available cape jasmine coordinates fermented soya bean, expels the heat-evil, relieving restlessness solution is strongly fragrant with saturating heresy.See the diseases such as high heat agitation, coma and delirium as belonged to a practical showing tremendous enthusiasm disease, available this product joins the purging intense heats such as golden cypress and heat symptoms caused by an exopathgen clearly.
Sealwort is used as medicine with rhizome.There is boosting qi and nourishing yin, invigorating the spleen, moistening lung, kidney benefiting functions.Be used for the treatment of weakness of the spleen and the stomach, fatigue and asthenia, dry food is few, deficiency syndrome of the lung cough caused by dryness, asthenia of essence and blood, and interior heat such as to be quenched one's thirst the disease.Very effective in cure for diabetes.Stir-baked RHIZOMA POLYGONATI with yellow rice wine is also known as processing sealwort.The person of being used as medicine is dried for clean sealwort steams rear section with the auxiliary material such as wine and black soya bean.Have the merit of channels and collaterals of escaping concurrently.Sealwort has hypotensive, hypoglycemic, reducing blood lipid, atherosclerosis, and delay senility and effect such as antibacterial grade, Siberian solomonseal rhizome polysaccharide has Immunestimulatory effect.For the lung-dryness syndrome due to yin deficiency, the few phlegm of dry cough, and the labor of lung-kidney deficiency is coughed chronic cough etc.For weakness of the spleen and the stomach.Both tonifying spleen-yin, again beneficial temper, obtain dizzy, soreness and weakness of waist and knees for deficiency of kidney essence, poliosis and quenching one's thirst.Sealwort strengthens the bone, beneficial marrow, bleaches and sends out; The cough phlegm be suitable for caused by lack of lung-YIN is few, dry cough without phlegm, the diseases such as hemoptysis.
Specific embodiment 1:
Annual spring plucks wilsonii tender leaf, first the free of contamination acanthopanax of anosis worm plucked is put into water and rinses, and after taking out, airing is on ventilative bamboo mat, and upset airing 7-12 hours, parches collection; The acanthopanax that airing is good is put into roller fixation device complete, complete 20-40 minute at 80-100 DEG C.Acanthopanax after just completing again dries in the shade after taking out naturally, puts into large iron pan and kneads, and kneads, firmly want evenly on first backward downwards, and when filament leaf bar rope is comparatively tight, baking machine turning in stir-fry 30-45 minute of putting into 50-60 DEG C when becoming dark brown is shaping.Naturally dried by the acanthopanax stir-fried, put into fragrance extracting machine Titian 30-40 minute, temperature controls in 50-60 DEG C, naturally dries after taking out.Then other bulk drugs are made granule or pulvis, mixing, ultraviolet sterilization is packed.
Specific embodiment 2:
Annual spring plucks wilsonii tender leaf, first the free of contamination acanthopanax of anosis worm plucked is put into water and rinses, and after taking out, airing is on ventilative bamboo mat, and upset airing 7-12 hours, parches and collect general 5000g; The acanthopanax that airing is good is put into roller fixation device complete, complete 20-40 minute at 80-100 DEG C.Acanthopanax after just completing again dries in the shade after taking out naturally, puts into large iron pan and kneads, and kneads, firmly want evenly on first backward downwards, and when filament leaf bar rope is comparatively tight, baking machine turning in stir-fry 30-45 minute of putting into 50-60 DEG C when becoming dark brown is shaping.Naturally dried by the acanthopanax stir-fried, put into fragrance extracting machine Titian 30-40 minute, temperature controls in 50-60 DEG C, naturally dries after taking out, get other bulk drug root barks of Chinese wolf-berry 1500g again, Poria cocos 1500g, cortex albiziae 1500g, Radix Astragali 1500g, red sage root 1500g, Fructus Corni 1500g, barrenwort 1500g, mulberries 1500g, fruit of Chinese magnoliavine 1500g, fruit of glossy privet 1500g, cassia seed 1500g, grass-leaved sweetflag 1500g, cape jasmine 1500g, sealwort 1500g, Radix Codonopsis 1500g, add in the ethanol of 5-10 times amount and soak 1-2 hour, heating extraction 2 times, each 1-2 hour, remove supernatant, merge above-mentioned two kinds of extracts, 100-120 order filters, be the ultrafiltration post ultrafiltration of 5000-10000 again through the molecular weight that dams, when ultrafiltrate reduced pressure concentration relative density is 80 DEG C 1.36 medicinal extract, heating is concentrated into paste, stand for standby use, again the dregs of a decoction extracted are added in the water of 5-10 times amount and soak 1-2 hour, heating extraction 2 times, each 1-2 hour, remove supernatant, merge above-mentioned two kinds of extracts, 100-120 order filters, be the ultrafiltration post ultrafiltration of 5000-10000 again through the molecular weight that dams, when ultrafiltrate reduced pressure concentration relative density is 80 DEG C 1.36 medicinal extract, extract medicinal extract by above-mentioned two kinds to merge, reducing pressure after reclaiming ethanol, it is concentrated to put into inspissator, by gained concentrate adjustment proportion to 1.40, reduce pressure to obtain medicinal extract, put into dryer to dry, then add honey to be in harmonious proportion, put into the granule that granulator makes 0.1-0.2 centimetre, then mix the acanthopanax made, ultraviolet sterilization packs.
Specific embodiment 3:
Annual spring plucks wilsonii tender leaf, first the free of contamination acanthopanax of anosis worm plucked is put into water and rinses, and after taking out, airing is on ventilative bamboo mat, and upset airing 7-12 hours, parches and collect general 4000g; The acanthopanax that airing is good is put into roller fixation device complete, complete 20-40 minute at 80-100 DEG C.Acanthopanax after just completing again dries in the shade after taking out naturally, puts into large iron pan and kneads, and kneads, firmly want evenly on first backward downwards, and when filament leaf bar rope is comparatively tight, baking machine turning in stir-fry 30-45 minute of putting into 50-60 DEG C when becoming dark brown is shaping.Naturally dried by the acanthopanax stir-fried, put into fragrance extracting machine Titian 30-40 minute, temperature controls in 50-60 DEG C, naturally dries after taking out, get other bulk drug root barks of Chinese wolf-berry 1100g again, Poria cocos 1200g, cortex albiziae 1200g, Radix Astragali 1100g, red sage root 1200g, Fructus Corni 1100g, barrenwort 1100g, mulberries 1100g, fruit of Chinese magnoliavine 1100g, fruit of glossy privet 1100g, cassia seed 1100g, grass-leaved sweetflag 1100g, cape jasmine 1100g, sealwort 1100g, Radix Codonopsis 1100g, shredded 100 ~ 120 mesh sieves, after sieving, fine powder is for subsequent use, coarse granule puts into acid and alkali-resistance infusion kettle, at room temperature, 3 ~ 7 days are flooded together with more than 70 degree ethanol, then heating and refluxing extraction 2 times, each 1 ~ 2 hour, No. 2 extracts are merged and leaves standstill, filter, filtrate is got after separation, by filtered through gauze, 50-60% ethanol is added in residue, 60 DEG C-70 DEG C are continued lixiviate 2h, and every 10min stirs once, filtered through gauze, merge leaching liquor, be condensed into pasty state to insert in economic benefits and social benefits vacuum concentrator, when being concentrated into 80 DEG C, relative density is the medicinal extract of 1.60, and the pasty state ointment after concentrated is dried to pulvis, then mix the acanthopanax made, ultraviolet sterilization packs.
Specific embodiment 4:
Annual spring plucks wilsonii tender leaf, first the free of contamination acanthopanax of anosis worm plucked is put into water and rinses, and after taking out, airing is on ventilative bamboo mat, and upset airing 7-12 hours, parches and collect general 4500g; The acanthopanax that airing is good is put into roller fixation device complete, complete 20-40 minute at 80-100 DEG C.Acanthopanax after just completing again dries in the shade after taking out naturally, puts into large iron pan and kneads, and kneads, firmly want evenly on first backward downwards, and when filament leaf bar rope is comparatively tight, baking machine turning in stir-fry 30-45 minute of putting into 50-60 DEG C when becoming dark brown is shaping.Naturally dried by the acanthopanax stir-fried, put into fragrance extracting machine Titian 30-40 minute, temperature controls in 50-60 DEG C, naturally dries after taking out; Get other bulk drug root barks of Chinese wolf-berry 1300g again, Poria cocos 1200g, cortex albiziae 1200g, Radix Astragali 1200g, red sage root 1200g, Fructus Corni 1100g, barrenwort 1100g, mulberries 1300g, fruit of Chinese magnoliavine 1200g, fruit of glossy privet 1100g, cassia seed 1100g, grass-leaved sweetflag 1100g, cape jasmine 1200g, all the other bulk drugs are put into the ethanol accounting for its quality 10 times amount and are soaked more than 24 hours by sealwort 1300g, Radix Codonopsis 1100g, No. 2 extracts each 1 ~ 2 hour, are merged and leave standstill by heating and refluxing extraction 2 times; The dregs of a decoction of the medicinal material crossed by above-mentioned alcohol extract again add the water heating and refluxing extraction 2 times accounting for its quality 10 times amount, each 1 ~ 2 hour, No. 2 extracts are merged and leaves standstill, extract medicinal extract 4 times to merge, when reduced pressure concentration relative density is 80 DEG C 1.28 pasty state, reclaim ethanol, gained pasty state is passed into spray dryer and carries out spraying dry, the compressed air pressure crossing spray dryer shower nozzle is 4kg/m
2, hothouse hot stream temperature is 80 DEG C, obtains bulk drug medicinal powder medicine, then mixes the acanthopanax made, and ultraviolet sterilization packs.
Toxicity test of science
Experimental example 1: acute toxicity test of the present invention
One, test material: animal: Kunming mouse, body weight 18-25g, male and female half and half, Shandong University's biology laboratory breeding.Medicine: the present invention's (all raw material mixing decoction 2 times merges and filters, taking liquid) is containing 0.0365mg/ml.
Two, method:
1, LD50 calculates: adopt improvement karber's method, mouse is divided into 5 groups at random, often organize 10, male and female half and half, dissolve adding distil water of the present invention, are made into Cmax, by the administration of mouse maximum permission capacity, institute is followed successively by 18,14.4 to dosage by crude drug amount, 11.5,9.2,7.4 (g.kg-1), in animal fasting (can't help water) after 18 hours, administration at twice in one day (interval half an hour), each 0.5ml, observes animal dead situation.
2, maximum tolerated dose measures (MTD value): get mouse 20, each 10 of male and female.Adding distil water of the present invention is dissolved, is made into maximum concentration, by the maximal tolerance dose of animal, feed device and can twitch to inject to fill with and be as the criterion.In animal fasting (can't help water) after 18 hours, administration at twice in one day (interval half an hour), each 0.5ml (every ml containing crude drug 0.36g), total dose is 18g crude drug/kg.d, 300 times of quite clinical adult 50Kg body weight consumption.Continuous Observation 7 days after administration.
Three, result of the test:
In LD50 calculates when giving mouse with maximum acceptable concentration and maximum permission capacity (18g/Kg.d), have no dead mouse, namely LD50 is not measured, ask maximum tolerated dose only, in 7 day observation period, its appetite of animal, activity, hair color, the state of mind etc. are all normal, grow normal, there are no death.Namely select the 300 times of doses being equivalent to clinical dosage, and have no adverse reaction, show that acute toxicity is minimum, MTD > 18g/Kg.d.
Experimental example 2: the result of the test of acute toxicity and long term toxicity
Acute toxicity test: give the present invention by the disposable gavage of small white mouse, maximum concentration 35%, maximum gavage capacity 0.4ml/10g, dosage 14g/kg (every g medicinal powder is equivalent to 10g crude drug), Continuous Observation 7 days, do not find any toxic reaction, because concentration and dosage cannot increase, therefore fail to measure the LD50 of this medicine.Maximum tolerance determination: with maximum concentration, maximum gavage capacity, mice lavage administration 3 times, 5 hours, interval, then Continuous Observation 7 days, none example is dead.Medicinal powder dosage is > 42g/kg. day (every g medicinal powder is equivalent to 10g crude drug), calculates 420 times of the clinical consumption per day that is equivalent to be grown up by kg body weight.
Long term toxicity test: whether produce toxic reaction for observing long-term prescription, give rat the present invention respectively and raise clothes, by adult 70 times of clinical consumption per day and 35 times (i.e. 7g/kg/ day and 3.5g/kg/ day), give continuously and feed 8 weeks, have no the behavior of rat, feed, body weight appearance extremely, with control group ratio, routine blood test, hepatic and renal function, the change all without exception of various important organ, within the scope of institute's dosage, do not find any toxicity of the present invention.Confirmed by the acute and chronic toxicity test of animal, safe range of the present invention is comparatively large, is a kind of safe and reliable health products.
Pharmacological experiment:
1 materials and methods
1.1 animal Kunming mouses, male, body weight 18 ~ 22g.Being thered is provided by Military Medical Science Institute's Experimental Animal Center. each group mouse all under the same conditions, freely drinks water, ingests, keeps natural daylight.
1.2 medicine acanthopanaxes, grass-leaved sweetflag, fruit of glossy privet Deng Jungou Chinese medicine pharmacy, after soaking 30min, decoct 30min, and twice merging filtrate is condensed into every 1ml containing 1g crude drug, 4 DEG C of Refrigerator stores.Positive drug DESIPRAMINE (SIGMA company, lot number: 200-373-1).Cortisol kit is provided by Shandong University.Standard items: norepinephrine (Norepinephrine, NE, Sigma company, lot number; 200-095-0); Dopamine (Dopamine, DA, Sigma company, lot number: 200-527-8) serotonin (5-hydroxytryptamine, 5-HT, Sigma company, lot number: 153-98-0); 5-HIAA (5-hydrooxyindole-3-aceticacid, 5-HIAA, Sigma company, lot number: 200-195-4) trisodium citrate; Perchloric acid (Beijing chemical reagent work analyzes pure); Methyl alcohol (Beijing chemical reagent work, chromatographically pure); Water is experiment ultra-pure water.
1.3 instrument 1050 type high performance liquid chromatographs (Hewlett-Packard of the U.S.); 1046 type fluorescence detectors (Hewlett-Packard of the U.S.); BondaparPhenyl chromatographic column (waters company of the U.S.); 15R hypervelocity refrigerated centrifuge (U.S. Heraeusbiofuge).
2 experimental techniques
2.1 mouse antidepressant effect experiments
2.1.1 experiment grouping and administration: be administration 1 day, 3 days, 5 days, 7 days, 14 days district's groups by random for mouse district component, each district group is divided into control group, positive controls at random, the high, medium and low dosage group of the present invention.Control group is given and physiological saline 0.2ml/20g, and positive controls is given and Desipramine0.2mg/20g, and high, medium and low dosage group is given and crude drug 0.12ml/20g, 0.06ml/20g, 0.03ml/20g.Each group of gavage, 1 times/day.
2.1.2 the mensuration of mouse dead time: each district group mouse carries out forced swim test after successive administration last.Mouse is put into high 20cm, in the glass beaker of diameter 10cm, the dark 10cm of water in the cup, water temperature 25 DEG C ± 1,1, each beaker, starts after 2min to observe, observes and continue 4min, mouse dead time (stop struggling or aobvious floating state, only have the duration that tiny limb motion is kept afloat to keep head) in water in this 4min accumulative.
2.2 Determination o cortisols: the mouse after swimming is extractd eyeball and gets blood, and (5000rmin-1) centrifugal 5min at a high speed, separation of serum, puts-70 DEG C of Refrigerator stores to be measured.Adopt radio immunoassay (RIA) to measure Determination of cortisol, operating procedure by specification carries out.
2.4 statistical method experimental result application SPSS statistical softwares, adopt variance analysis, and group difference T inspection is carried out, and acquired results x ± S represents.
3. result
3.1 the present invention are on the impact of mouse antidepressant effect
Table 1 the present invention is on the impact (X ± S) of mouse antidepressant effect
* P < 0.05** P < 0.01 compared with control group compared with control group
3.2 the present invention are on the impact of mice plasma cortisol
Table 2 the present invention is on the impact (X ± S) of mice plasma Determination of cortisol
* P < 0.05## P < 0.01 compared with normal group compared with control group
Discuss: this experiment adopts a kind of stable, reliable, classical antifatigue model---forced swimming model, investigate antifatigue effect of the present invention and carried out Study on mechanism simultaneously, measure the present invention to the impact of tuber on content of monoamine transmitters in depression model mice plasma Determination of cortisol and brain.Result shows, each dosage group of the present invention all can shorten the dead time during mouse antidepressant effect in various degree, has significant statistical significance compared with control group.Prompting the present invention has the effect of obvious antifatigue and anxiety, but desipramine has obvious side effect, and the present invention is without any side effects.
Specific embodiment: Ma, man, 35 years old, in first visit on April 2 in 2013.Readme is the little leader of company, and every day is at office building, but easy catching a cold, insomnia and dreamful sleep, easily dry, face is obscure, fatiguability, hypoimmunity.Blood item, B ultrasonic has no pathology.Love life starts to be discord, and oneself is somewhat unable to do what one wishes.A variety of causes makes immune system normally can not play protective effect, and in the case, very easily cause the infection such as bacterium, virus, fungi, therefore hypoimmunity the most directly shows is exactly liable to illness.Because of often ill, increased the weight of the consumption of body, thus generally have a delicate constitution, malnutritive, One's spirits are drooping, fatigue and weak, appetite reduce, life quality reduction, the performances such as sleep-disorder, sick, have an injection and take medicine the normal potluck that just gets married.At every turn sickly all will could to recover for a long time, and usually recurrent exerbation, because taking medicine throughout the year, produces resentment to medicine, suggestion health tea-drinking replaces taking Chinese medicine.
Fang Yong: acanthopanax 25g, root bark of Chinese wolf-berry 11g, Poria cocos 12g, cortex albiziae 13g, Radix Astragali 11g, red sage root 12g, Fructus Corni 13g, barrenwort 12g, mulberries 13g, fruit of Chinese magnoliavine 11g, fruit of glossy privet 12g, cassia seed 12g, grass-leaved sweetflag 13g, cape jasmine 11g, sealwort 12g, Radix Codonopsis 12g, makes tea bag, and every day two wraps, after taking 6 days, patient is conscious, and all diseases are improved, and appetite increases, sleep-disorder lowers, One's spirits are drooping improvement, fatigue and weak improve, continue to take 1 month, think that oneself is full of vigour, sleeps, continue to use every day, all diseases all disappear, healthy self-confident.
Claims (10)
1. the acanthopanax root health tea of an antifatigue, it is characterized in that, described acanthopanax root health tea comprises the bulk drug of following parts by weight: acanthopanax 10 ~ 50 parts, the root bark of Chinese wolf-berry 10 ~ 20 parts, 10 ~ 20 parts, Poria cocos, cortex albiziae 10 ~ 20 parts, the Radix Astragali 10 ~ 20 parts, the red sage root 10 ~ 20 parts, Fructus Corni 10 ~ 20 parts, barrenwort 10 ~ 20 parts, mulberries 10 ~ 20 parts, 10 ~ 20 parts, the fruit of Chinese magnoliavine, the fruit of glossy privet 10 ~ 20 parts, cassia seed 10 ~ 20 parts, grass-leaved sweetflag 10 ~ 20 parts, cape jasmine 10 ~ 20 parts, sealwort 10 ~ 20 parts, Radix Codonopsis 10 ~ 20 parts.
2. the acanthopanax root health tea of antifatigue according to claim 1, it is characterized in that, described acanthopanax root health tea comprises the bulk drug of following parts by weight: acanthopanax 10 ~ 30 parts, the root bark of Chinese wolf-berry 10 ~ 15 parts, 10 ~ 15 parts, Poria cocos, cortex albiziae 10 ~ 15 parts, the Radix Astragali 10 ~ 15 parts, the red sage root 10 ~ 15 parts, Fructus Corni 10 ~ 15 parts, barrenwort 10 ~ 15 parts, mulberries 10 ~ 20 parts, 10 ~ 20 parts, the fruit of Chinese magnoliavine, the fruit of glossy privet 10 ~ 20 parts, cassia seed 10 ~ 20 parts, grass-leaved sweetflag 10 ~ 20 parts, cape jasmine 10 ~ 20 parts, sealwort 10 ~ 20 parts, Radix Codonopsis 10 ~ 20 parts.
3. the acanthopanax root health tea of antifatigue according to claim 1, it is characterized in that, described acanthopanax root health tea comprises the bulk drug of following parts by weight: acanthopanax 10 ~ 40 parts, the root bark of Chinese wolf-berry 10 ~ 20 parts, fuling peel 10 ~ 20 parts, cortex albiziae 10 ~ 20 parts, the Radix Astragali 10 ~ 20 parts, the red sage root 10 ~ 20 parts, Fructus Corni 10 ~ 20 parts, barrenwort 10 ~ 20 parts, mulberries 10 ~ 15 parts, 10 ~ 15 parts, the fruit of Chinese magnoliavine, the fruit of glossy privet 10 ~ 15 parts, cassia seed 10 ~ 15 parts, grass-leaved sweetflag 10 ~ 15 parts, cape jasmine 10 ~ 15 parts, sealwort 10 ~ 15 parts, Radix Codonopsis 10 ~ 15 parts.
4. the preparation method of the acanthopanax root health tea of antifatigue as described in any one of claims 1 to 3 item, it is characterized in that, the preparation process of described acanthopanax root health tea comprises following aspect:
A. first the acanthopanax plucked is cleaned and dry, then put into roller fixation machine and complete;
B. the electric frying pan put into by acanthopanax after terminating that completes stir-fries shaping;
C. shaping acanthopanax is put into and is carried camera Titian;
D. all the other bulk drugs described are prepared into granule or pulvis,
E. by the acanthopanax prepared and the granule obtained or pulvis mixing, pack shaping.
5. the preparation method of the acanthopanax root health tea of antifatigue according to claim 4, it is characterized in that, in described step a, annual spring plucks wilsonii tender leaf, first the free of contamination acanthopanax of anosis worm plucked is put into water to rinse, after taking out, airing is on ventilative bamboo mat, and upset airing 7-12 hours, parches collection; The acanthopanax that airing is good is put into roller fixation device complete, complete 20-40 minute at 80-100 DEG C.
6. the preparation method of the acanthopanax root health tea of antifatigue according to claim 4, it is characterized in that, in described step b, acanthopanax taking-up after completing is dried in the shade afterwards naturally, put into large iron pan to knead, knead on first backward downwards, firmly want evenly, when filament leaf bar rope is comparatively tight, the baking machine turning in putting into 50-60 DEG C when becoming dark brown fry 30-45 minute shaping.
7. the preparation method of the acanthopanax root health tea of antifatigue according to claim 4, is characterized in that, in described step c, the acanthopanax stir-fried is dried naturally, put into fragrance extracting machine Titian 30-40 minute, temperature controls in 50-60 DEG C, naturally dries after taking out.
8. the preparation method of the acanthopanax root health tea of antifatigue according to claim 4, it is characterized in that, in described steps d, the preparation method making granule when all the other bulk drugs is, surplus stock medicine component is put into the ethanol accounting for its quality 10 times amount, heating and refluxing extraction 2 times, each 1-2 hour, remove supernatant, merge extract, 100-110 order filters, be the ultrafiltration post ultrafiltration of 6000-10000 again through the molecular weight that dams, when ultrafiltrate reduced pressure concentration relative density is 80 DEG C 1.36 medicinal extract, heating be concentrated into paste, stand for standby use; The dregs of a decoction of the component bulk drug medicinal material crossed by above-mentioned alcohol extract again add the water heating and refluxing extraction 2 times accounting for its quality 10 times amount, remove supernatant, merge extract, 100-110 order filters, be the ultrafiltration post ultrafiltration of 6000-10000 again through the molecular weight that dams, when ultrafiltrate reduced pressure concentration relative density is 80 DEG C 1.36 medicinal extract, heating be concentrated into paste, stand for standby use; Extract medicinal extract by above-mentioned two kinds to merge, reducing pressure after reclaiming ethanol, it is concentrated to put into inspissator, by gained concentrate adjustment proportion to 1.40; reduce pressure to obtain medicinal extract; put into dryer to dry, then add honey or dextrin mediation, put into the granule that granulator makes 0.1-0.2 centimetre.
9. the preparation method of the acanthopanax root health tea of antifatigue according to claim 4, it is characterized in that, in described steps d, the preparation method when all the other bulk drugs make pulvis is: mixed by described parts by weight by all the other bulk drug medicines described, shredded 100 ~ 120 mesh sieves, after sieving, fine powder is for subsequent use, coarse granule puts into acid and alkali-resistance infusion kettle, at room temperature, floods 10 ~ 15 days together with more than 70 degree ethanol, the liquid flooded and the dregs of a decoction are carried out squeeze and filter, after separation, gets filtrate; Described filtrate heating is concentrated into pasty state, puts into drying in oven, after cooling, grind to form fine powder; Add the fine powder obtained sieved, be mixed into pulvis.
10. the preparation method of the acanthopanax root health tea of antifatigue according to claim 4, is characterized in that, in described step e, will obtain granule in steps d or pulvis mixes with the acanthopanax that above-mentioned steps makes, after ultraviolet sterilization, pack packaging is shaping.
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| CN107173482A (en) * | 2017-07-04 | 2017-09-19 | 贵州省分析测试研究院 | Prevent health protection tea and its preparation technology of inferior health |
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| CN105943833B (en) * | 2016-06-16 | 2020-03-27 | 绥化学院 | Anti-fatigue traditional Chinese medicine health tea for physical exercise |
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