CN105168286A

CN105168286A - Externally-applied medicine for treating herpes zoster

Info

Publication number: CN105168286A
Application number: CN201510711763.1A
Authority: CN
Inventors: 吴淑芬
Original assignee: Individual
Current assignee: Individual
Priority date: 2015-10-28
Filing date: 2015-10-28
Publication date: 2015-12-23

Abstract

The invention discloses externally-applied medicine for treating herpes zoster. The externally-applied medicine is prepared from, by weight, 2-8 parts of pearls, 5-15 parts of calculus bovis, 5-15 parts of realgar, 2-8 parts of borneol, 5-15 parts of arenobufagin, 5-15 parts of musk, 5-15 parts of panax notoginseng, 5-15 parts of cinnabar and 25-35 parts of rice vinegar. According to the externally-applied medicine, raw materials are scientifically and reasonably matched and support one another, and through combination of the raw medical materials, the effects of clearing away heat and toxic materials and activating blood to promote menstruation and relieve pain are realized, treatment time is short, and the medicine becomes effective fast and is free of toxic and side effects. The medicine is especially suitable for treating herpes zoster.

Description

A kind of application compress for the treatment of herpes zoster

Technical field

The present invention relates to technical field of pharmaceuticals, be specifically related to a kind of application compress for the treatment of herpes zoster.

Background technology

Herpes zoster is the actute infection dermatoses caused by varicella-zoster virus.After infected to this viral child without immunity, there is chickenpox.Become carrier after some patients is infected and symptom do not occur.Because virus has neurotropism, can hide for a long time in the neuron of spinal nerves posterior root ganglion after infection, when lower for the resistance or tired, infection, flu, virus can regrow breeding, and move to skin along nerve fiber, make the nerve of being invaded and skin produce strong inflammation.Erythra generally has feature that is Unilateral and that distribute by nerve segment, is made up of the herpes of collection bunch property, and with pain; Age is larger, and neuralgia is heavier.

At present, the medicine for external use for the treatment of herpes zoster is generally famciclovir emulsifiable paste, valaciclovir emulsifiable paste and Virless Cream, is all guanine analog class antiviral drugs.Due to containing active component acyclovir, following untoward reaction in various degree can be produced, one, skin and mucous membrane irritation symptom, erythema, drying, pruritus appear in local skin, sting thorn, burn feeling etc., can disappear after decrement or drug withdrawal; Its two, contact dermatitis, there is the erythra such as redness, maculopapule, blister, erosion in local skin, can with pruritus, burn, the irritation such as pain, drug withdrawal and can disappearing to after antiallergic agent; In addition, long-term large area heavy dose uses and may cause Systemic reaction, feels sick, suffers from abdominal pain, suffers from diarrhoea, blood change, liver enzyme raise, renal function injury, headache, perspiration, hypotension and mental symptom etc. as occurred.In addition, treatment time long, take effect slow.

Summary of the invention

For the deficiencies in the prior art, the object of this invention is to provide a kind ofly to have no adverse reaction, the application compress of the treatment herpes zoster of instant effect, short treating period.

In order to achieve the above object, the technical scheme that the present invention takes is:

Treat application compress for herpes zoster, its component is by weight: Margarita 2 ~ 8 parts, Calculus Bovis 5 ~ 15 parts, Realgar 5 ~ 15 parts, Borneolum Syntheticum 2 ~ 8 parts, Venenum Bufonis 5 ~ 15 parts, 5 ~ 15 parts, Moschus, Radix Notoginseng 5 ~ 15 parts, 5 ~ 15 parts, Cinnabaris, rice vinegar 25 ~ 35 parts.

As preferred component, its component is by weight: Margarita 3 ~ 7 parts, Calculus Bovis 7 ~ 13 parts, Realgar 7 ~ 13 parts, Borneolum Syntheticum 3 ~ 7 parts, Venenum Bufonis 7 ~ 13 parts, 7 ~ 13 parts, Moschus, Radix Notoginseng 7 ~ 13 parts, 7 ~ 13 parts, Cinnabaris, rice vinegar 27 ~ 33 parts.

As preferred component, its component is by weight: Margarita 4 ~ 6 parts, Calculus Bovis 9 ~ 11 parts, Realgar 9 ~ 11 parts, Borneolum Syntheticum 4 ~ 6 parts, Venenum Bufonis 9 ~ 11 parts, 9 ~ 11 parts, Moschus, Radix Notoginseng 9 ~ 11 parts, 9 ~ 11 parts, Cinnabaris, rice vinegar 29 ~ 31 parts.

As better composition, its component is by weight: Margarita 5 parts, Calculus Bovis 10 parts, Realgar 10 parts, Borneolum Syntheticum 5 parts, Venenum Bufonis 10 parts, 10 parts, Moschus, Radix Notoginseng 10 parts, 10 parts, Cinnabaris, rice vinegar 30 parts.

The preparation method of this liniment: take each component by weight, first by Margarita, Calculus Bovis, Realgar, Borneolum Syntheticum, Venenum Bufonis, Moschus, Cinnabaris crude drug pulverization, then is adjusted to pasty state ointment with rice vinegar.

The Therapeutic Method of this liniment: ointment is smeared herpes place, can cover herpes and skin lesion for degree, as flowing water person of festering, available medicamental pulverata is directly spread on affected part, 3 times on the one, continuous one week.

Medicine of the present invention has following pharmacology:

Margarita, property of medicine sweet in the mouth, salty, cold in nature, there is effect of calm the nerves arresting convulsion, liver heat removing and eyesight improving, removing toxic substances and promoting granulation, be mainly used in palpitation with fear severe palpitation, vexed insomnia, infantile convulsion epilepsy, cataract, aphtha of the mouth and tongue, throat burst rotten, the symptom such as skin infection does not close up for a long time.

Calculus Bovis, property of medicine bitter in the mouth, sweet, cool in nature, there is the cool liver that clears away heart-fire, eliminate phlegm for resuscitation, effect of heat-clearing and toxic substances removing, be mainly used in calentura coma, apoplexy key closes, infantile convulsion tic, acute infantile convulsion, swelling throat are rotten, the symptom such as aphtha of the mouth and tongue, carbuncle furunculosis.

Realgar, property of medicine acrid, bitter, warm, poisonous, there is dampness, eliminate the phlegm, parasite killing, removing toxic substances effect, be mainly used in the symptoms such as carbuncle furuncle, acute gangrenous stomatitis, acute throat trouble sore throat, scabies, herpes zoster, eczema of lower limb, hemorrhoid, snake bite and insect sting, malnutrition due to parasitic infestation, infantile convulsion, malaria, asthma.

Borneolum Syntheticum, the property of medicine is pungent, bitter, cool, has effect of refreshment of having one's ideas straightened out, heat radiation pain relieving, improving eyesight removing nebula, is mainly used in the symptoms such as apoplexy locked mouth, calentura coma, infantile convulsion expectorant fan, deafness with qi stagnation, conjunctivitis, sore throat, aphtha, carbuncle, hemorrhoid, enterobiasis;

Venenum Bufonis, property of medicine acrid in the mouth, warm in nature, poisonous, symptoms such as there is reducing swelling and alleviating pain, dirty effect is warded off in removing toxic substances, be mainly used in carbuncle furuncle, laryngopharynx swelling and pain, wind carious pain, gingiva swell rotten, acute filthy disease stomachache.

Moschus, property of medicine acrid in the mouth, warm in nature, there is effect of refreshment of having one's ideas straightened out, blood circulation promoting and dispersing pathogen accumulation, alleviating pain and detumescence, be mainly used in calentura and kill the symptom such as dusk, apoplexy syncope due to accumulation of phlegm, stagnation of QI sudden syncope, attacked by pestiferous factors stupor, blood stasis amenorrhea, lumps in the chest and abdomen, trusted subordinate's shoot, traumatic injury, arthralgia pain numbness, carbuncle malignant boil, sore throat, aphtha, ulcerative gingivitis, glue ear.

Radix Notoginseng, property of medicine sweet in the mouth, micro-hardship, property are wet, have effect of hemostasis, loose blood, analgesic therapy, are mainly used in falling flutterring the symptom such as congestive edema, thoracic obstruction angor, mass in the abdomen, blood stasis amenorrhea, dysmenorrhea, the stasis of blood in puerperal cloudy stomachache, sore, carbuncle and painful swelling.

Cinnabaris, the property of medicine is sweet, cool, poisonous, has effect of tranquilizing mind, heat-clearing and toxic substances removing, improving eyesight, is mainly used in the symptom such as demented, palpitation with fear, vexed, insomnia, dizzy, blurred vision, toxic swelling, skin infection.

Rice vinegar, the property of medicine is sour, sweet, warm, effect of the dissipating blood stasis removing food stagnancy had, hemostasis, relieving colic caused by ascaris, removing toxic substances, is mainly used in puerperal blood faints, lumps in the chest and abdomen, haematemesis, epistaxis, has blood in stool, the symptom such as abdominal pain due to worm stagnation, flesh of fish dish poison, carbuncle sore tumefacting virus.

Compared with prior art, the benefit that the present invention has: starting components science, compatibility are reasonable, support mutually, all medicines share, and have heat-clearing and toxic substances removing, the effect of promoting blood circulation to restore menstrual flow pain relieving, treatment time short, instant effect, have no side effect, be particularly suitable for the use for the treatment of herpes zoster.

Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:

Patient data: patient 80 example, wherein man 42 example, female 38 example, at 15 ~ 62 years old age, be divided into treatment group 40 example and matched group 40 example at random, on the basis in conjunction with oral antiviral treatment, and treatment group external application medicine of the present invention; Matched group external application Virless Cream.Two groups of data there was no significant differences such as sex, age, have comparability.

Efficacy determination: effective: pain weakened, subsides a swelling in 1 day, incrustation in 3 days, cures for 5 days; Effective: within 2 days, pain weakens, subsides a swelling, and forms a scab after 4 days, within 6 days, cure; Invalid: pain reduces, detumescence was more than 2 days, and incrustation, more than 4 days, is cured more than 6 days.

Treatment total effective rate=(recovery from illness+effective+effectively)/total number of cases × 100%.

Treatment statistical result is as shown in the table:

Group	Number of cases	Effective	Effectively	Invalid	Total effective rate
						Treatment group	40	35	3	2	95％
Matched group	40	24	10	6	85％

Visible, liniment of the present invention treatment Herpes Zoster is obvious, treatment group apparently higher than matched group, detumescence, pain subtract, form a scab, on average the successful of curative day be better than matched group.

Detailed description of the invention

Below in conjunction with specific embodiment, the present invention is further described.

Embodiment 1

First, take each component: Margarita 2 parts, Calculus Bovis 15 parts, Realgar 15 parts, Borneolum Syntheticum 3 parts, Venenum Bufonis 15 parts, 15 parts, Moschus, Radix Notoginseng 5 parts, 5 parts, Cinnabaris, rice vinegar 25 parts.

Prepare ointment: first by Margarita, Calculus Bovis, Realgar, Borneolum Syntheticum, Venenum Bufonis, Moschus, Cinnabaris crude drug pulverization, then be adjusted to pasty state ointment with rice vinegar.

Therapeutic Method: ointment is smeared herpes place, can cover herpes and skin lesion for degree, as flowing water person of festering, available medicamental pulverata is directly spread on affected part, 3 times on the one, continuous one week.

Embodiment 2

First, take each component: Margarita 3 parts, Calculus Bovis 13 parts, Realgar 13 parts, Borneolum Syntheticum 4 parts, Venenum Bufonis 13 parts, 13 parts, Moschus, Radix Notoginseng 7 parts, 7 parts, Cinnabaris, rice vinegar 27 parts.

Prepare ointment: identical with embodiment 1.

Therapeutic Method: identical with embodiment 1.

Embodiment 3

First, take each component: Margarita 5 parts, Calculus Bovis 10 parts, Realgar 10 parts, Borneolum Syntheticum 5 parts, Venenum Bufonis 10 parts, 10 parts, Moschus, Radix Notoginseng 10 parts, 10 parts, Cinnabaris, rice vinegar 30 parts.

Prepare ointment: identical with embodiment 1.

Therapeutic Method: identical with embodiment 1.

Embodiment 4

First, take each component: Margarita 6 parts, Calculus Bovis 8 parts, Realgar 8 parts, Borneolum Syntheticum 6 parts, Venenum Bufonis 8 parts, 8 parts, Moschus, Radix Notoginseng 12 parts, 12 parts, Cinnabaris, rice vinegar 32 parts.

Prepare ointment: identical with embodiment 1.

Therapeutic Method: identical with embodiment 1.

Embodiment 5

First, take each component: Margarita 8 parts, Calculus Bovis 5 parts, Realgar 5 parts, Borneolum Syntheticum 7 parts, Venenum Bufonis 5 parts, 5 parts, Moschus, Radix Notoginseng 15 parts, 15 parts, Cinnabaris, rice vinegar 35 parts.

Prepare ointment: identical with embodiment 1.

Therapeutic Method: identical with embodiment 1.

It should be pointed out that above case is only the representational example of the present invention.Obviously, technical scheme of the present invention is not limited to above-described embodiment, can also have many degeneration.

Claims

1. treat application compress for herpes zoster, it is characterized in that, its component is by weight: Margarita 2 ~ 8 parts, Calculus Bovis 5 ~ 15 parts; Realgar 5 ~ 15 parts, Borneolum Syntheticum 2 ~ 8 parts, Venenum Bufonis 5 ~ 15 parts, 5 ~ 15 parts, Moschus; Radix Notoginseng 5 ~ 15 parts, 5 ~ 15 parts, Cinnabaris, rice vinegar 25 ~ 35 parts.

2. a kind of application compress for the treatment of herpes zoster according to claim 1; it is characterized in that; its component is by weight: Margarita 3 ~ 7 parts, Calculus Bovis 7 ~ 13 parts, Realgar 7 ~ 13 parts; Borneolum Syntheticum 3 ~ 7 parts; Venenum Bufonis 7 ~ 13 parts, 7 ~ 13 parts, Moschus, Radix Notoginseng 7 ~ 13 parts; 7 ~ 13 parts, Cinnabaris, rice vinegar 27 ~ 33 parts.

3. a kind of application compress for the treatment of herpes zoster according to claim 2; it is characterized in that; its component is by weight: Margarita 4 ~ 6 parts, Calculus Bovis 9 ~ 11 parts, Realgar 9 ~ 11 parts; Borneolum Syntheticum 4 ~ 6 parts; Venenum Bufonis 9 ~ 11 parts, 9 ~ 11 parts, Moschus, Radix Notoginseng 9 ~ 11 parts; 9 ~ 11 parts, Cinnabaris, rice vinegar 29 ~ 31 parts.

4. a kind of application compress for the treatment of herpes zoster according to claim 3, it is characterized in that, its component is by weight: Margarita 5 parts, Calculus Bovis 10 parts, Realgar 10 parts, Borneolum Syntheticum 5 parts, Venenum Bufonis 10 parts, 10 parts, Moschus, Radix Notoginseng 10 parts, 10 parts, Cinnabaris, rice vinegar 30 parts.