CN105166912B - A kind of compound Moringa stem of noble dendrobium oral liquid and preparation method thereof - Google Patents
A kind of compound Moringa stem of noble dendrobium oral liquid and preparation method thereof Download PDFInfo
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- CN105166912B CN105166912B CN201510688155.3A CN201510688155A CN105166912B CN 105166912 B CN105166912 B CN 105166912B CN 201510688155 A CN201510688155 A CN 201510688155A CN 105166912 B CN105166912 B CN 105166912B
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- 235000011347 Moringa oleifera Nutrition 0.000 title claims abstract description 49
- 239000007788 liquid Substances 0.000 title claims abstract description 40
- 240000004638 Dendrobium nobile Species 0.000 title claims abstract description 31
- 150000001875 compounds Chemical class 0.000 title claims abstract description 22
- 238000002360 preparation method Methods 0.000 title claims abstract description 14
- 244000179886 Moringa oleifera Species 0.000 title description 35
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 18
- 241000026010 Dendrobium candidum Species 0.000 claims abstract description 15
- 239000000843 powder Substances 0.000 claims abstract description 11
- 239000000706 filtrate Substances 0.000 claims abstract description 8
- 238000001914 filtration Methods 0.000 claims abstract description 8
- 229930006000 Sucrose Natural products 0.000 claims abstract description 4
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 claims abstract description 4
- 238000012856 packing Methods 0.000 claims abstract description 4
- WXMKPNITSTVMEF-UHFFFAOYSA-M sodium benzoate Chemical compound [Na+].[O-]C(=O)C1=CC=CC=C1 WXMKPNITSTVMEF-UHFFFAOYSA-M 0.000 claims abstract description 4
- 235000010234 sodium benzoate Nutrition 0.000 claims abstract description 4
- 239000004299 sodium benzoate Substances 0.000 claims abstract description 4
- 230000001954 sterilising effect Effects 0.000 claims abstract description 4
- 239000005720 sucrose Substances 0.000 claims abstract description 4
- 238000010438 heat treatment Methods 0.000 claims abstract description 3
- 241000220215 Moringa Species 0.000 claims abstract 15
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 claims description 17
- 229910052742 iron Inorganic materials 0.000 claims description 9
- 230000000694 effects Effects 0.000 claims description 6
- 230000008859 change Effects 0.000 claims description 4
- 231100000215 acute (single dose) toxicity testing Toxicity 0.000 claims description 3
- 238000005119 centrifugation Methods 0.000 claims description 3
- 238000013112 stability test Methods 0.000 claims description 3
- 238000010171 animal model Methods 0.000 claims description 2
- 238000004140 cleaning Methods 0.000 claims description 2
- 239000004575 stone Substances 0.000 claims 1
- 239000000284 extract Substances 0.000 abstract 1
- 229920003266 Leaf® Polymers 0.000 description 11
- 239000011575 calcium Substances 0.000 description 4
- 229910052791 calcium Inorganic materials 0.000 description 4
- 150000004676 glycans Chemical class 0.000 description 4
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 3
- 241000196324 Embryophyta Species 0.000 description 3
- 210000004698 lymphocyte Anatomy 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 229920001282 polysaccharide Polymers 0.000 description 3
- 239000005017 polysaccharide Substances 0.000 description 3
- 108090000623 proteins and genes Proteins 0.000 description 3
- 102000004169 proteins and genes Human genes 0.000 description 3
- 210000000952 spleen Anatomy 0.000 description 3
- SRBFZHDQGSBBOR-IOVATXLUSA-N D-xylopyranose Chemical compound O[C@@H]1COC(O)[C@H](O)[C@H]1O SRBFZHDQGSBBOR-IOVATXLUSA-N 0.000 description 2
- 241001076416 Dendrobium tosaense Species 0.000 description 2
- 241000220214 Moringaceae Species 0.000 description 2
- 150000001413 amino acids Chemical class 0.000 description 2
- 238000004458 analytical method Methods 0.000 description 2
- PYMYPHUHKUWMLA-UHFFFAOYSA-N arabinose Natural products OCC(O)C(O)C(O)C=O PYMYPHUHKUWMLA-UHFFFAOYSA-N 0.000 description 2
- SRBFZHDQGSBBOR-UHFFFAOYSA-N beta-D-Pyranose-Lyxose Natural products OC1COC(O)C(O)C1O SRBFZHDQGSBBOR-UHFFFAOYSA-N 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 230000036541 health Effects 0.000 description 2
- 230000036737 immune function Effects 0.000 description 2
- 230000036039 immunity Effects 0.000 description 2
- 229910052500 inorganic mineral Inorganic materials 0.000 description 2
- 239000008267 milk Substances 0.000 description 2
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- 210000004080 milk Anatomy 0.000 description 2
- 239000011707 mineral Substances 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 239000002504 physiological saline solution Substances 0.000 description 2
- 108090000765 processed proteins & peptides Proteins 0.000 description 2
- 239000000725 suspension Substances 0.000 description 2
- 235000015961 tonic Nutrition 0.000 description 2
- 230000001256 tonic effect Effects 0.000 description 2
- PFTAWBLQPZVEMU-DZGCQCFKSA-N (+)-catechin Chemical compound C1([C@H]2OC3=CC(O)=CC(O)=C3C[C@@H]2O)=CC=C(O)C(O)=C1 PFTAWBLQPZVEMU-DZGCQCFKSA-N 0.000 description 1
- 206010000117 Abnormal behaviour Diseases 0.000 description 1
- 238000011725 BALB/c mouse Methods 0.000 description 1
- WQZGKKKJIJFFOK-QTVWNMPRSA-N D-mannopyranose Chemical compound OC[C@H]1OC(O)[C@@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-QTVWNMPRSA-N 0.000 description 1
- 244000000626 Daucus carota Species 0.000 description 1
- 235000002767 Daucus carota Nutrition 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 241000594394 Hedyotis Species 0.000 description 1
- 238000012449 Kunming mouse Methods 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 240000008790 Musa x paradisiaca Species 0.000 description 1
- 235000018290 Musa x paradisiaca Nutrition 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 241000233855 Orchidaceae Species 0.000 description 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 1
- 244000300264 Spinacia oleracea Species 0.000 description 1
- 235000009337 Spinacia oleracea Nutrition 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 238000011047 acute toxicity test Methods 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- 230000003064 anti-oxidating effect Effects 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- PYMYPHUHKUWMLA-WDCZJNDASA-N arabinose Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)C=O PYMYPHUHKUWMLA-WDCZJNDASA-N 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
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- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 238000001516 cell proliferation assay Methods 0.000 description 1
- 230000001413 cellular effect Effects 0.000 description 1
- 210000003169 central nervous system Anatomy 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 230000006806 disease prevention Effects 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 239000000686 essence Substances 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 230000004438 eyesight Effects 0.000 description 1
- 230000004927 fusion Effects 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 230000037308 hair color Effects 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 230000006698 induction Effects 0.000 description 1
- 238000001802 infusion Methods 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 239000002932 luster Substances 0.000 description 1
- 229910052749 magnesium Inorganic materials 0.000 description 1
- 239000011777 magnesium Substances 0.000 description 1
- 229910052748 manganese Inorganic materials 0.000 description 1
- 239000011572 manganese Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000011987 methylation Effects 0.000 description 1
- 238000007069 methylation reaction Methods 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 210000004400 mucous membrane Anatomy 0.000 description 1
- 239000013642 negative control Substances 0.000 description 1
- VIKNJXKGJWUCNN-XGXHKTLJSA-N norethisterone Chemical compound O=C1CC[C@@H]2[C@H]3CC[C@](C)([C@](CC4)(O)C#C)[C@@H]4[C@@H]3CCC2=C1 VIKNJXKGJWUCNN-XGXHKTLJSA-N 0.000 description 1
- 235000021590 normal diet Nutrition 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000000050 nutritive effect Effects 0.000 description 1
- 230000035790 physiological processes and functions Effects 0.000 description 1
- 150000004804 polysaccharides Polymers 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- 229910052700 potassium Inorganic materials 0.000 description 1
- 230000035935 pregnancy Effects 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 230000035755 proliferation Effects 0.000 description 1
- 150000003254 radicals Chemical class 0.000 description 1
- 230000029058 respiratory gaseous exchange Effects 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 210000004988 splenocyte Anatomy 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 229960000716 tonics Drugs 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
- 235000013311 vegetables Nutrition 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/38—Other non-alcoholic beverages
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The invention discloses a kind of compound Moringa stem of noble dendrobium oral liquid and preparation method thereof, the component of the compound Moringa stem of noble dendrobium oral liquid is:The preparation method includes:Dendrobium candidum cleans, and is crushed to fineness as 20 30 mesh, adds in 80 90 DEG C of degree water and impregnates 2 3h, extracts 34 times, the filtering of 100 mesh screens, and 6000rpm centrifuges 35 45min, and heating is concentrated into 1/5th amounts, and the mass ratio of dendrobium candidum and hot water is 1: 30 35;The leaf of Moringa powder with the quality such as dendrobium candidum is taken, 55 60 DEG C of water is added in and impregnates 30 45min, impregnate 23 times, filtering merges two kinds of filtrates, spare;The mass ratio of leaf of Moringa powder and water is 1: 41: 6;The filtrate of merging is concentrated into half;Add in 1 12 sucrose and 2/1000ths sodium benzoate of total amount of liquid;Packing, 105 DEG C of steam sterilizings.
Description
Technical field
The invention belongs to health care technology field more particularly to a kind of compound Moringa stem of noble dendrobium oral liquid and its preparation sides
Method.
Background technology
Moringa (Moringa sp.), common entitled Moringa, Drumstick or Horseradish tree of English, also
Someone is translated into " oily Moringa " " horseradish tree " or " drumstick tree ", is Moringaceae (Moringaceae) Moringa (Moringa
Adans.) perennial plant originates in the torrid zone, the arid of south subtropics or semiarid zone, and can bloom knot after planting 6 months
Actually multipurpose fast-growing arbor species.Leaf of Moringa is eaten extensively, and nutritive value is the heat of international community common concern
Point.Being measured according to quality of vegetable supervision and inspection center of the Ministry of Agriculture proves, contains albumen in the Moringa blade per 100g
27.1 grams of matter, about the 2 of milk times;Containing 00 milligram of Catergen, about the 7 of orange times;Containing 6.3 milligrams of retinol1, about
4 times of carrot;28.2 milligrams of iron content, about the 3 of spinach times;2003 milligrams of calcic, about the 4 of milk times;Containing 1324 milli of potassium
Gram, about the 3 of banana times.Therefore, the fresh leaf of the 200g VA and VC demand daily with regard to that can meet children, 100g fresh leafs can meet 1
Calcium, 75% iron and protein needed for~3 years old children;The leaf powder of 25g, containing child it is daily needed for 270% VA, 42%
Protein, 125% calcium, 70% iron and 22% Vc;The leaf powder of 50g can meet needed for pregnancy period and women breast-feeding their children's whole day
Iron and calcium.Dendrobium candidum (scientific name:Dendrobium officinale Kimura et Migo) also known as:Ribbed hedyotis herb, Yunnan iron
Skin.Belong to micro- specific item, the perennial herbaceous plant that grows nonparasitically upon another plant of orchid family.Stem is upright, cylindrical, 9-35 centimetres long, 2-4 millimeter thick, sepal with
Petal yellow green, near similar, long round shape lanceolar is about 1.8cm, wide 4~5mm, 3~June of florescence.It is distributed mainly on middle Guoan
The ground such as emblem, Zhejiang, Fujian.Its stem is used as medicine, and belongs to the yin tonics in tonic.It promotes the production of body fluid nourishing the stomach;Nourishing Yin and clearing heat;Moistening lung kidney-nourishing;Improving eyesight
Strong waist.The polysaccharide component of dendrobium candidum is the principle active component of dendrobium candidum, and polysaccharide component can remove free radical, is had anti-
Oxidation activity can adjust immunity of organisms, prevent inferior health, reduce the generation of disease, inhibit tumour, slow down aging.Yang Hong
Dendrobium officinale polysaccharide structure is studied Deng with the methods of sugared composition analysis, methylation analysis, is therefrom isolated for the first time
DT2, DT3 mainly contain glucose, galactolipin, xylose and a small amount of arabinose and mannose.It is removed in dendrobium candidum and contains polysaccharide
Outside, also containing the several mineral materials such as 17 kinds of amino acid and Mg, Ca, Fe, Mn, Zn.Amino acid by peptide key connection can become peptide with
Protein, these are all the histiocytic ultimate constituents of life entity;Minerals are in the adjusting of human body physiological function and a variety of
It also all occupies an important position in the prevention of disease, is the essential nutritional ingredient of human body.
Invention content
The purpose of the present invention is to provide a kind of compound Moringa stem of noble dendrobium oral liquids and preparation method thereof, it is intended to further fusion
The Biofunctional of leaf of Moringa and dendrobium candidum.
The purpose of the present invention is to provide a kind of compound Moringa stem of noble dendrobium oral liquids, and it is one that the effect of Moringa and stem of noble dendrobium, which is melted,
Body, the component Moringa of the compound Moringa stem of noble dendrobium oral liquid and the mass ratio of the stem of noble dendrobium are 1: 1.
Another object of the present invention is to provide a kind of preparation method of compound Moringa stem of noble dendrobium oral liquid, the compound Moringa
The preparation method of stem of noble dendrobium oral liquid includes the following steps:
Step 1, dendrobium candidum cleaning, and fineness is crushed to as 20-30 mesh, it adds in 80-90 DEG C of degree water and impregnates 2-3h, iron
The mass ratio of the skin stem of noble dendrobium and hot water is 1: 30-35, is extracted 3-4 times, the filtering of 100 mesh screens, and 6000rpm centrifugation 35-45min add
/ 5th of liquid volume before thermal concentration to concentration;
Step 2 takes the leaf of Moringa powder with the quality such as dendrobium candidum, adds in 55-60 DEG C of water and impregnates 30-45min, impregnates 2-3
Secondary, filtering merges two kinds of filtrates, spare;The mass ratio of leaf of Moringa powder and water is 1: 4-1: 6;
Step 3, the filtrate of merging are concentrated into half;
Step 4 adds in the sucrose of total liquid quality 12% and 2 ‰ sodium benzoate of total liquid quality;
Step 5, packing, 105 DEG C of steam sterilizings.
Further, the instructions of taking of the compound Moringa stem of noble dendrobium oral liquid is each 10-20ml, 1-2 times daily.
Compound Moringa stem of noble dendrobium oral liquid provided by the invention and preparation method thereof, the brown liquid of acquisition is tried through stability
Test is determined, and significant change does not occur in six months for room temperature, and is measured through acute toxicity testing, and the maximum of daily 40ml intends dosage not
Lead to experimental animal abnormal behavior, dosage safety;Extraction merges the active ingredient of Moringa and the stem of noble dendrobium, promotes the work(of Moringa and the stem of noble dendrobium
Effect complements one another, and is measured through lymphocyte proliferation assay, stimulus index (SI) > 2 of oral liquid, has certain immune function
Facilitation.
Description of the drawings
Fig. 1 is the preparation method flow chart of compound Moringa stem of noble dendrobium oral liquid provided in an embodiment of the present invention.
Specific embodiment
In order to make the purpose , technical scheme and advantage of the present invention be clearer, with reference to embodiments, to the present invention
It is further elaborated.It should be appreciated that the specific embodiments described herein are merely illustrative of the present invention, it is not used to
Limit the present invention.
The method that the present invention is extracted by aqueous solution obtains the effective active composition in leaf of Moringa and dendrobium candidum, and by two
Person is mixed into oral liquid, and the raising of new product Moringa stem of noble dendrobium oral liquid processed by spleen lymphocyte proliferation measuring is immunized
Power activity.
The mass ratio of the compound Moringa stem of noble dendrobium oral liquid of the embodiment of the present invention is:1∶1.
The application principle of the present invention is explained in detail below in conjunction with the accompanying drawings.
As shown in Figure 1, the preparation method of the compound Moringa stem of noble dendrobium oral liquid of the embodiment of the present invention includes the following steps:
S101:Dendrobium candidum cleans, and is crushed to fineness as 20-30 mesh, adds in 80-90 DEG C of degree water and impregnates 2-3h, iron sheet
The mass ratio of the stem of noble dendrobium and hot water is 1: 30-35, is extracted 3-4 times, the filtering of 100 mesh screens, 6000rpm centrifugation 35-45min, heating
It is concentrated into 1/5th of liquid volume before concentrating;
S102:The leaf of Moringa powder with the quality such as dendrobium candidum is taken, 55-60 DEG C of water is added in and impregnates 30-45min, impregnate 2-3
Secondary, filtering merges two kinds of filtrates, spare;The mass ratio of leaf of Moringa powder and water is 1: 4-1: 6;
S103:The filtrate of merging is concentrated into half;
S104:Add in the sucrose of total liquid quality 12% and 2 ‰ sodium benzoate of total liquid quality;
S105:Packing, 105 DEG C of steam sterilizings.
The application effect of the present invention is described in detail by following experiment:
1st, stability test:Oral liquid 3 batches is taken, is placed at room temperature for 6 months, observation clarity, color and luster change, as a result oral liquid
Stablize, without significant change.
2nd, acute toxicity test:Take SPF grades of Kunming mouses 20, half male and half female;Fasting in 12 hours, freely drinks before administration
Water, every animal are respectively administered once by 40ml/kg gastric infusions in afternoon in the morning, observation mouse skin, mucous membrane, hair color, eyes,
Breathing, cycle and central nervous system, independent behaviour performance etc., give the mouse of physiological saline as negative control.It is continuous to see
Examine 14d, two groups of equal normal diets of mouse.
3rd, strengthen immunity measures:The mouse spleen lymphocyte transformation experiment (mtt assay) of ConA inductions.With 6-8 week old
BALB/c mouse, orally administration mouse 10ml/kg.bw, successive administration 30 days give the mouse of physiological saline as negative right
According to.It is sterile after 30 days to take spleen, and individual cells suspension is made.Holes will be divided to add in 24 well culture plates per a splenocyte suspension
In, per hole 1mL, a hole adds 75 μ L ConA liquid (being equivalent to 7.5 μ g/mL), and 72h is cultivated in another hole as compareing in CO2 incubators.
4h adds in MTT (5mg/mL) 50 μ L/ holes before culture terminates, and continues to cultivate 4h.After culture, 1mL acid isopropyls are added in per hole
Alcohol after blowing and beating mixing, is dispensed into 96 well culture plates, and OD value is measured with 570nm wavelength with microplate reader.Experimental result table
Bright, the compound Moringa stem of noble dendrobium takes orally the cellular immune function of liquid energy enhancing mouse.
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all essences in the present invention
All any modification, equivalent and improvement made within refreshing and principle etc., should all be included in the protection scope of the present invention.
Claims (1)
- A kind of 1. preparation method of compound Moringa stem of noble dendrobium oral liquid, which is characterized in that the system of the compound Moringa stem of noble dendrobium oral liquid Preparation Method includes the following steps:Step 1, dendrobium candidum cleaning, and fineness is crushed to as 20-30 mesh, it adds in 80-90 DEG C of degree water and impregnates 2-3h, iron sheet stone The mass ratio of dry measure used in former times and hot water is 1: 30-35, is extracted 3-4 times, the filtering of 100 mesh screens, 6000rpm centrifugation 35-45min, and heating is dense It is reduced to 1/5th of liquid volume before concentrating;Step 2 takes the leaf of Moringa powder with the quality such as dendrobium candidum, adds in 55-60 DEG C of water and impregnates 30-45min, impregnates 2-3 times, The mass ratio of leaf of Moringa powder and water is 1: 4-1: 6;Filtering merges two kinds of filtrates, spare;The mass ratio of leaf of Moringa powder and water is 1: 4-1∶6;Step 3, the filtrate of merging are concentrated into half;Step 4 adds in the sucrose of total liquid quality 12% and 2 ‰ sodium benzoate of total liquid quality;Step 5, packing, 105 DEG C of steam sterilizings;The instructions of taking of the compound Moringa stem of noble dendrobium oral liquid is each 10-20ml, 1-2 times daily;The compound Moringa stem of noble dendrobium oral liquid combines the effect of Moringa and stem of noble dendrobium together, the compound Moringa stem of noble dendrobium oral liquid The mass ratio of component Moringa and the stem of noble dendrobium is 1: 1;The brown liquid that the preparation method of the compound Moringa stem of noble dendrobium oral liquid obtains, measures, room temperature six through stability test Significant change does not occur, and measure through acute toxicity testing in month, the maximum dosage of intending of daily 40ml does not result in experimental animal row For exception, dosage safety.
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CN104432075A (en) * | 2014-12-25 | 2015-03-25 | 福州嘉佑化学科技有限公司 | Moringa oleifera leaf oral liquid and preparation method thereof |
CN104544038A (en) * | 2013-10-29 | 2015-04-29 | 广西浙商投资有限公司 | Dendrobium officinale oral liquid preparation and processing method |
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JP4032393B2 (en) * | 2004-07-09 | 2008-01-16 | 有限会社イッシンランバー | Nutritional function supplements, Moringa tea leaves and Moringa tea drinks |
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CN101612316A (en) * | 2009-07-23 | 2009-12-30 | 浙江天皇药业有限公司 | The application of dendrobium officinale aqueous extract in the medicine of preparation prophylactic treatment hypertension apoplexy |
CN104544038A (en) * | 2013-10-29 | 2015-04-29 | 广西浙商投资有限公司 | Dendrobium officinale oral liquid preparation and processing method |
CN104432075A (en) * | 2014-12-25 | 2015-03-25 | 福州嘉佑化学科技有限公司 | Moringa oleifera leaf oral liquid and preparation method thereof |
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