CN105166912B - A kind of compound Moringa stem of noble dendrobium oral liquid and preparation method thereof - Google Patents

A kind of compound Moringa stem of noble dendrobium oral liquid and preparation method thereof Download PDF

Info

Publication number
CN105166912B
CN105166912B CN201510688155.3A CN201510688155A CN105166912B CN 105166912 B CN105166912 B CN 105166912B CN 201510688155 A CN201510688155 A CN 201510688155A CN 105166912 B CN105166912 B CN 105166912B
Authority
CN
China
Prior art keywords
moringa
stem
noble dendrobium
oral liquid
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN201510688155.3A
Other languages
Chinese (zh)
Other versions
CN105166912A (en
Inventor
李佳忠
李振梅
泮林
侯庆爱
王莹
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shandong Technician College
Original Assignee
李佳忠
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 李佳忠 filed Critical 李佳忠
Priority to CN201510688155.3A priority Critical patent/CN105166912B/en
Publication of CN105166912A publication Critical patent/CN105166912A/en
Application granted granted Critical
Publication of CN105166912B publication Critical patent/CN105166912B/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/38Other non-alcoholic beverages
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

Landscapes

  • Health & Medical Sciences (AREA)
  • Nutrition Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

The invention discloses a kind of compound Moringa stem of noble dendrobium oral liquid and preparation method thereof, the component of the compound Moringa stem of noble dendrobium oral liquid is:The preparation method includes:Dendrobium candidum cleans, and is crushed to fineness as 20 30 mesh, adds in 80 90 DEG C of degree water and impregnates 2 3h, extracts 34 times, the filtering of 100 mesh screens, and 6000rpm centrifuges 35 45min, and heating is concentrated into 1/5th amounts, and the mass ratio of dendrobium candidum and hot water is 1: 30 35;The leaf of Moringa powder with the quality such as dendrobium candidum is taken, 55 60 DEG C of water is added in and impregnates 30 45min, impregnate 23 times, filtering merges two kinds of filtrates, spare;The mass ratio of leaf of Moringa powder and water is 1: 41: 6;The filtrate of merging is concentrated into half;Add in 1 12 sucrose and 2/1000ths sodium benzoate of total amount of liquid;Packing, 105 DEG C of steam sterilizings.

Description

A kind of compound Moringa stem of noble dendrobium oral liquid and preparation method thereof
Technical field
The invention belongs to health care technology field more particularly to a kind of compound Moringa stem of noble dendrobium oral liquid and its preparation sides Method.
Background technology
Moringa (Moringa sp.), common entitled Moringa, Drumstick or Horseradish tree of English, also Someone is translated into " oily Moringa " " horseradish tree " or " drumstick tree ", is Moringaceae (Moringaceae) Moringa (Moringa Adans.) perennial plant originates in the torrid zone, the arid of south subtropics or semiarid zone, and can bloom knot after planting 6 months Actually multipurpose fast-growing arbor species.Leaf of Moringa is eaten extensively, and nutritive value is the heat of international community common concern Point.Being measured according to quality of vegetable supervision and inspection center of the Ministry of Agriculture proves, contains albumen in the Moringa blade per 100g 27.1 grams of matter, about the 2 of milk times;Containing 00 milligram of Catergen, about the 7 of orange times;Containing 6.3 milligrams of retinol1, about 4 times of carrot;28.2 milligrams of iron content, about the 3 of spinach times;2003 milligrams of calcic, about the 4 of milk times;Containing 1324 milli of potassium Gram, about the 3 of banana times.Therefore, the fresh leaf of the 200g VA and VC demand daily with regard to that can meet children, 100g fresh leafs can meet 1 Calcium, 75% iron and protein needed for~3 years old children;The leaf powder of 25g, containing child it is daily needed for 270% VA, 42% Protein, 125% calcium, 70% iron and 22% Vc;The leaf powder of 50g can meet needed for pregnancy period and women breast-feeding their children's whole day Iron and calcium.Dendrobium candidum (scientific name:Dendrobium officinale Kimura et Migo) also known as:Ribbed hedyotis herb, Yunnan iron Skin.Belong to micro- specific item, the perennial herbaceous plant that grows nonparasitically upon another plant of orchid family.Stem is upright, cylindrical, 9-35 centimetres long, 2-4 millimeter thick, sepal with Petal yellow green, near similar, long round shape lanceolar is about 1.8cm, wide 4~5mm, 3~June of florescence.It is distributed mainly on middle Guoan The ground such as emblem, Zhejiang, Fujian.Its stem is used as medicine, and belongs to the yin tonics in tonic.It promotes the production of body fluid nourishing the stomach;Nourishing Yin and clearing heat;Moistening lung kidney-nourishing;Improving eyesight Strong waist.The polysaccharide component of dendrobium candidum is the principle active component of dendrobium candidum, and polysaccharide component can remove free radical, is had anti- Oxidation activity can adjust immunity of organisms, prevent inferior health, reduce the generation of disease, inhibit tumour, slow down aging.Yang Hong Dendrobium officinale polysaccharide structure is studied Deng with the methods of sugared composition analysis, methylation analysis, is therefrom isolated for the first time DT2, DT3 mainly contain glucose, galactolipin, xylose and a small amount of arabinose and mannose.It is removed in dendrobium candidum and contains polysaccharide Outside, also containing the several mineral materials such as 17 kinds of amino acid and Mg, Ca, Fe, Mn, Zn.Amino acid by peptide key connection can become peptide with Protein, these are all the histiocytic ultimate constituents of life entity;Minerals are in the adjusting of human body physiological function and a variety of It also all occupies an important position in the prevention of disease, is the essential nutritional ingredient of human body.
Invention content
The purpose of the present invention is to provide a kind of compound Moringa stem of noble dendrobium oral liquids and preparation method thereof, it is intended to further fusion The Biofunctional of leaf of Moringa and dendrobium candidum.
The purpose of the present invention is to provide a kind of compound Moringa stem of noble dendrobium oral liquids, and it is one that the effect of Moringa and stem of noble dendrobium, which is melted, Body, the component Moringa of the compound Moringa stem of noble dendrobium oral liquid and the mass ratio of the stem of noble dendrobium are 1: 1.
Another object of the present invention is to provide a kind of preparation method of compound Moringa stem of noble dendrobium oral liquid, the compound Moringa The preparation method of stem of noble dendrobium oral liquid includes the following steps:
Step 1, dendrobium candidum cleaning, and fineness is crushed to as 20-30 mesh, it adds in 80-90 DEG C of degree water and impregnates 2-3h, iron The mass ratio of the skin stem of noble dendrobium and hot water is 1: 30-35, is extracted 3-4 times, the filtering of 100 mesh screens, and 6000rpm centrifugation 35-45min add / 5th of liquid volume before thermal concentration to concentration;
Step 2 takes the leaf of Moringa powder with the quality such as dendrobium candidum, adds in 55-60 DEG C of water and impregnates 30-45min, impregnates 2-3 Secondary, filtering merges two kinds of filtrates, spare;The mass ratio of leaf of Moringa powder and water is 1: 4-1: 6;
Step 3, the filtrate of merging are concentrated into half;
Step 4 adds in the sucrose of total liquid quality 12% and 2 ‰ sodium benzoate of total liquid quality;
Step 5, packing, 105 DEG C of steam sterilizings.
Further, the instructions of taking of the compound Moringa stem of noble dendrobium oral liquid is each 10-20ml, 1-2 times daily.
Compound Moringa stem of noble dendrobium oral liquid provided by the invention and preparation method thereof, the brown liquid of acquisition is tried through stability Test is determined, and significant change does not occur in six months for room temperature, and is measured through acute toxicity testing, and the maximum of daily 40ml intends dosage not Lead to experimental animal abnormal behavior, dosage safety;Extraction merges the active ingredient of Moringa and the stem of noble dendrobium, promotes the work(of Moringa and the stem of noble dendrobium Effect complements one another, and is measured through lymphocyte proliferation assay, stimulus index (SI) > 2 of oral liquid, has certain immune function Facilitation.
Description of the drawings
Fig. 1 is the preparation method flow chart of compound Moringa stem of noble dendrobium oral liquid provided in an embodiment of the present invention.
Specific embodiment
In order to make the purpose , technical scheme and advantage of the present invention be clearer, with reference to embodiments, to the present invention It is further elaborated.It should be appreciated that the specific embodiments described herein are merely illustrative of the present invention, it is not used to Limit the present invention.
The method that the present invention is extracted by aqueous solution obtains the effective active composition in leaf of Moringa and dendrobium candidum, and by two Person is mixed into oral liquid, and the raising of new product Moringa stem of noble dendrobium oral liquid processed by spleen lymphocyte proliferation measuring is immunized Power activity.
The mass ratio of the compound Moringa stem of noble dendrobium oral liquid of the embodiment of the present invention is:1∶1.
The application principle of the present invention is explained in detail below in conjunction with the accompanying drawings.
As shown in Figure 1, the preparation method of the compound Moringa stem of noble dendrobium oral liquid of the embodiment of the present invention includes the following steps:
S101:Dendrobium candidum cleans, and is crushed to fineness as 20-30 mesh, adds in 80-90 DEG C of degree water and impregnates 2-3h, iron sheet The mass ratio of the stem of noble dendrobium and hot water is 1: 30-35, is extracted 3-4 times, the filtering of 100 mesh screens, 6000rpm centrifugation 35-45min, heating It is concentrated into 1/5th of liquid volume before concentrating;
S102:The leaf of Moringa powder with the quality such as dendrobium candidum is taken, 55-60 DEG C of water is added in and impregnates 30-45min, impregnate 2-3 Secondary, filtering merges two kinds of filtrates, spare;The mass ratio of leaf of Moringa powder and water is 1: 4-1: 6;
S103:The filtrate of merging is concentrated into half;
S104:Add in the sucrose of total liquid quality 12% and 2 ‰ sodium benzoate of total liquid quality;
S105:Packing, 105 DEG C of steam sterilizings.
The application effect of the present invention is described in detail by following experiment:
1st, stability test:Oral liquid 3 batches is taken, is placed at room temperature for 6 months, observation clarity, color and luster change, as a result oral liquid Stablize, without significant change.
2nd, acute toxicity test:Take SPF grades of Kunming mouses 20, half male and half female;Fasting in 12 hours, freely drinks before administration Water, every animal are respectively administered once by 40ml/kg gastric infusions in afternoon in the morning, observation mouse skin, mucous membrane, hair color, eyes, Breathing, cycle and central nervous system, independent behaviour performance etc., give the mouse of physiological saline as negative control.It is continuous to see Examine 14d, two groups of equal normal diets of mouse.
3rd, strengthen immunity measures:The mouse spleen lymphocyte transformation experiment (mtt assay) of ConA inductions.With 6-8 week old BALB/c mouse, orally administration mouse 10ml/kg.bw, successive administration 30 days give the mouse of physiological saline as negative right According to.It is sterile after 30 days to take spleen, and individual cells suspension is made.Holes will be divided to add in 24 well culture plates per a splenocyte suspension In, per hole 1mL, a hole adds 75 μ L ConA liquid (being equivalent to 7.5 μ g/mL), and 72h is cultivated in another hole as compareing in CO2 incubators. 4h adds in MTT (5mg/mL) 50 μ L/ holes before culture terminates, and continues to cultivate 4h.After culture, 1mL acid isopropyls are added in per hole Alcohol after blowing and beating mixing, is dispensed into 96 well culture plates, and OD value is measured with 570nm wavelength with microplate reader.Experimental result table Bright, the compound Moringa stem of noble dendrobium takes orally the cellular immune function of liquid energy enhancing mouse.
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all essences in the present invention All any modification, equivalent and improvement made within refreshing and principle etc., should all be included in the protection scope of the present invention.

Claims (1)

  1. A kind of 1. preparation method of compound Moringa stem of noble dendrobium oral liquid, which is characterized in that the system of the compound Moringa stem of noble dendrobium oral liquid Preparation Method includes the following steps:
    Step 1, dendrobium candidum cleaning, and fineness is crushed to as 20-30 mesh, it adds in 80-90 DEG C of degree water and impregnates 2-3h, iron sheet stone The mass ratio of dry measure used in former times and hot water is 1: 30-35, is extracted 3-4 times, the filtering of 100 mesh screens, 6000rpm centrifugation 35-45min, and heating is dense It is reduced to 1/5th of liquid volume before concentrating;
    Step 2 takes the leaf of Moringa powder with the quality such as dendrobium candidum, adds in 55-60 DEG C of water and impregnates 30-45min, impregnates 2-3 times, The mass ratio of leaf of Moringa powder and water is 1: 4-1: 6;Filtering merges two kinds of filtrates, spare;The mass ratio of leaf of Moringa powder and water is 1: 4-1∶6;
    Step 3, the filtrate of merging are concentrated into half;
    Step 4 adds in the sucrose of total liquid quality 12% and 2 ‰ sodium benzoate of total liquid quality;
    Step 5, packing, 105 DEG C of steam sterilizings;
    The instructions of taking of the compound Moringa stem of noble dendrobium oral liquid is each 10-20ml, 1-2 times daily;
    The compound Moringa stem of noble dendrobium oral liquid combines the effect of Moringa and stem of noble dendrobium together, the compound Moringa stem of noble dendrobium oral liquid The mass ratio of component Moringa and the stem of noble dendrobium is 1: 1;
    The brown liquid that the preparation method of the compound Moringa stem of noble dendrobium oral liquid obtains, measures, room temperature six through stability test Significant change does not occur, and measure through acute toxicity testing in month, the maximum dosage of intending of daily 40ml does not result in experimental animal row For exception, dosage safety.
CN201510688155.3A 2015-10-22 2015-10-22 A kind of compound Moringa stem of noble dendrobium oral liquid and preparation method thereof Expired - Fee Related CN105166912B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201510688155.3A CN105166912B (en) 2015-10-22 2015-10-22 A kind of compound Moringa stem of noble dendrobium oral liquid and preparation method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201510688155.3A CN105166912B (en) 2015-10-22 2015-10-22 A kind of compound Moringa stem of noble dendrobium oral liquid and preparation method thereof

Publications (2)

Publication Number Publication Date
CN105166912A CN105166912A (en) 2015-12-23
CN105166912B true CN105166912B (en) 2018-06-22

Family

ID=54889755

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201510688155.3A Expired - Fee Related CN105166912B (en) 2015-10-22 2015-10-22 A kind of compound Moringa stem of noble dendrobium oral liquid and preparation method thereof

Country Status (1)

Country Link
CN (1) CN105166912B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105942113A (en) * 2016-06-25 2016-09-21 韶关绿之源包装食品有限公司 Preparation method of dendrobium drink

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101612316A (en) * 2009-07-23 2009-12-30 浙江天皇药业有限公司 The application of dendrobium officinale aqueous extract in the medicine of preparation prophylactic treatment hypertension apoplexy
CN104432075A (en) * 2014-12-25 2015-03-25 福州嘉佑化学科技有限公司 Moringa oleifera leaf oral liquid and preparation method thereof
CN104544038A (en) * 2013-10-29 2015-04-29 广西浙商投资有限公司 Dendrobium officinale oral liquid preparation and processing method

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4032393B2 (en) * 2004-07-09 2008-01-16 有限会社イッシンランバー Nutritional function supplements, Moringa tea leaves and Moringa tea drinks

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101612316A (en) * 2009-07-23 2009-12-30 浙江天皇药业有限公司 The application of dendrobium officinale aqueous extract in the medicine of preparation prophylactic treatment hypertension apoplexy
CN104544038A (en) * 2013-10-29 2015-04-29 广西浙商投资有限公司 Dendrobium officinale oral liquid preparation and processing method
CN104432075A (en) * 2014-12-25 2015-03-25 福州嘉佑化学科技有限公司 Moringa oleifera leaf oral liquid and preparation method thereof

Also Published As

Publication number Publication date
CN105166912A (en) 2015-12-23

Similar Documents

Publication Publication Date Title
CN103906526B (en) Using medicinal flower parcel fermentation process and utilize its Dermatologic preparation composition
CN104856035A (en) Health-care product for recuperating specific intrinsic constitution
CN102058759B (en) Medicinal tea prepared from Chinese medicinal materials by microbial fermentation
CN102919949A (en) Plant health-care drink and preparation method thereof
CN104041903A (en) Selenium-rich cyclocarya paliurus beverage and preparation method thereof
CN106617062A (en) Selenium-enriched full-nutrition formula food capable of eliminating dampness of human body
CN105707629A (en) Selenium-rich salicornia herbacea health-care beverage
CN101869287B (en) Astragalus and honey soft capsule and preparation method thereof
CN106343567A (en) Noni oral liquid and preparing method thereof
CN106389788B (en) It is a kind of for enhancing the drug extract, preparation and preparation method of immunologic function of livestock and birds and anti-virus ability
CN103637218B (en) Healthcare honey and preparation method thereof
CN105166912B (en) A kind of compound Moringa stem of noble dendrobium oral liquid and preparation method thereof
TW200841829A (en) Instant tea
CN105495620A (en) Plant extract composition simultaneously having immunological enhancement and blood fat reducing functions
CN102604802B (en) Preparation method of originally ecological bamboo-germanium nutritional wine
CN106880042A (en) A kind of full nutrition formula food suitable for fat, fat reducing patient with operation convalescence
CN103734767A (en) Health-care food
CN102613648B (en) Preparation method of original ecological bamboo germanium nutrient solution
CN110477249A (en) A kind of nutritional preparation of suitable spacefarer's toxin expelling nourishing the stomach
CN101336719B (en) Nutrient powder capable of expelling toxin and preventing cancer
CN101194724B (en) Bamboo juice beverage
CN103720808B (en) A kind of composition and use thereof, preparation method with relieving constipation effect
CN111758809A (en) Astragalus membranaceus and samara leaf health-care tea
CN102824630B (en) Pharmaceutical composition for treating chicken proventriculitis and preparation method of pharmaceutical composition
CN105853505A (en) Qi-and-lung-tonifying healthcare medicine composition containing five-leaf gynostemma herb

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant
TR01 Transfer of patent right

Effective date of registration: 20190118

Address after: 250199 No. 7506 East Second Ring Road, Jinan City, Shandong Province

Patentee after: Shandong Technician College

Address before: 250014 No. 7506 East Second Ring Road, Jinan City, Shandong Province

Patentee before: Li Jiazhong

TR01 Transfer of patent right
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20180622

Termination date: 20191022

CF01 Termination of patent right due to non-payment of annual fee