CN105147445B - Intelligent constant-temperature hot compress paste - Google Patents

Intelligent constant-temperature hot compress paste Download PDF

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Publication number
CN105147445B
CN105147445B CN201510638008.5A CN201510638008A CN105147445B CN 105147445 B CN105147445 B CN 105147445B CN 201510638008 A CN201510638008 A CN 201510638008A CN 105147445 B CN105147445 B CN 105147445B
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agent
phase
temperature
layer
constant
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CN105147445A (en
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张亚超
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Henan Super Asia Medical Equipment Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/02Compresses or poultices for effecting heating or cooling
    • A61F7/03Compresses or poultices for effecting heating or cooling thermophore, i.e. self-heating, e.g. using a chemical reaction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/02Compresses or poultices for effecting heating or cooling
    • A61F2007/0261Compresses or poultices for effecting heating or cooling medicated

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  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Thermal Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Thermotherapy And Cooling Therapy Devices (AREA)

Abstract

A kind of intelligent constant-temperature hot compress paste, it is made up of pressure sensitive adhesive patch, heater, phase-change constant-temperature layer, layer of pharmaceutical composition and release liners, pressure sensitive adhesive patch, heater, phase-change constant-temperature layer, layer of pharmaceutical composition and release liners are arranged in order from the bottom to top, described heater is located at the centre of pressure sensitive adhesive patch, described phase-change constant-temperature layer is located at heater surface, phase-change constant-temperature layer contains agent by phase transition agent, particulate and flexible formation agent is constituted, by weight, it is matched as phase transition agent 40~60%, particulate contains agent 8~25%, flexible formation agent 18~48%.The present invention can reach automatic flat perseverance makes the temperature of skin-proximal keep constant, has safety guarantee higher as the medical products that skin uses are close to.

Description

Intelligent constant-temperature hot compress paste
Technical field
The present invention relates to a kind of medical supplies, for meridian point thermostimulation, more particularly to a kind of intelligent constant-temperature hot compress paste.
Background technology
Chemical heating agent is used to make self-heating moxibustion, the existing many patents of the class medical products of hot compress paste one.Such as CN201410734521 hot compress paste Press pin patents, exothermic mixture bag and thumb-tack needle for subcutaneous embedding are combined the self-heating moxibustion patch being designed to thumb-tack needle for subcutaneous embedding.This hair It is bright can dredging the channel, recuperating qi-blood, so as to reach rouse oneself yang-energy, stimulate circulation, dispel cold-evil, improve therapeutic efficiency; CN201420684248 combinations medicament magnetic material and chemical self-heating body devise medicine magnetic self-heating moxibustion, by pad pasting regulation heating temperature; CN201410329768 constant temperature spontaneous heatings moxibustion patch plays hot compress by the ceramic blister layer effect on human body that self-heating body is combined with magnetic material Effect.It is feasible that these schemes meet predetermined heating temp under standard use state, but is generally affixed on ring when human body is used Border temperature difference and wear clothing how much all influence its heating temperature, the temperature and preset temperature of performance are discrepant.
The content of the invention
The present invention provides one kind and can improve its security, eliminates unexpected injury, is capable of achieving the intelligent constant warm of intelligent constant-temperature Application.
In order to solve the above technical problems, the technical scheme is that:
A kind of intelligent constant-temperature hot compress paste, by pressure sensitive adhesive patch, heater, phase-change constant-temperature layer, layer of pharmaceutical composition and release Paper is constituted, and pressure sensitive adhesive patch, heater, phase-change constant-temperature layer, layer of pharmaceutical composition and release liners, institute are arranged in order from the bottom to top The heater stated is located at the centre of pressure sensitive adhesive patch, and described phase-change constant-temperature layer is located at heater surface, and phase-change constant-temperature layer is by phase Become agent, particulate and contain agent and flexible formation agent composition, by weight, its proportioning contains agent 8 for phase transition agent 40~60%, particulate ~25%, flexible formation agent 18~48%, described flexible formation agent is SBS resins and 200~400 DEG C of fraction atoleines, SBS Resin and 200~400 DEG C of fraction atoleines are with 1:(5~10)Proportions oil-base gel or hot-fusible pressure-sensitive adhesive, phase transformation The weight sum that agent contains agent with particulate is 1~3 times of the weight of flexible formation agent.
Further, described pressure sensitive adhesive patch coated using pressure sensitive adhesive and be made on non-woven fabrics.
Further, described phase-change constant-temperature layer coats or is bonded in the surface of heater.
Further, the phase transition agent in described phase-change constant-temperature layer selects the polyethylene glycol of mean molecule quantity 800~1200, Transformation temperature is at 40 DEG C~45 DEG C.
Further, the optimal transformation temperature of described phase transition agent is 43 DEG C.
Further, described particulate contains agent expanded vermiculite powder, swelling perlite powder, expanded graphite, montmorillonite, work Property carbon, gas phase of white carbon black one kind therein, particulate contains the weight that agent and phase transition agent prepare and is than scope(1~4):(4~1)It Between.
Further, described layer of pharmaceutical composition is calculated as 10~20 parts of greater celandine ethanol extract, poly- third by weight 2.4~8.5 parts of olefin(e) acid, 10~20 parts of glycerine, 0.3~0.9 part of aluminium chloride, 0.3~0.9 part of citric acid, 57~70 parts of water are obtained.
Further, in island morpheme in the centre of pressure sensitive adhesive patch, heater is warm patch to described heater.
The beneficial effects of the invention are as follows:
In structure, be can reach in normal service conditions although general self-heating paste application penetrates air by accurate control Under, temperature control is in setting range, but such as environment temperature difference is excessive or surface covering is blocked up, it is possible to exceed temperature By skin burn, intelligent constant-temperature hot compress paste of the present invention increases phase transformation to setting range on the basis of existing self-heating paste application technical scheme Heat storage structure, is absorbed heat when temperature is higher than transformation temperature, and intelligent constant-temperature, polyethylene glycol are realized in the heat release when temperature is less than transformation temperature Latent heat of phase change is 140-170kJ/kg, and iron powder heat production 69.5kJ/kg, such as heater have the total heat production of iron powder 10g for 695J, will send out Hot body standard highest heating temp control is within 48 DEG C, then 1.5g polyethylene glycol enthalpy of phase change 210J accounts for total amount of heat about 30% i.e. Can reach automatic flat perseverance makes the temperature of skin-proximal keep constant, has safety higher to protect as the medical products that skin uses are close to Barrier.
The temperature test table of comparisons:
_________________________________________________________
Non- constant temperature sample test maximum temperature constant temperature sample test maximum temperature
1 51.3℃ 1 43.7℃
2 46.1℃ 2 43.5℃
3 44.0℃ 3 43.7℃
4 44.7℃ 4 44.0℃
5 50.4℃ 5 43.3℃
_________________________________________________________
Brief description of the drawings
Fig. 1 is a kind of structural representation of intelligent constant-temperature hot compress paste of the invention.
Fig. 2 is a kind of structural representation of the vertical view of intelligent constant-temperature hot compress paste of the invention.
Sequence number in figure:1 is pressure sensitive adhesive patch, and 2 is heater, and 3 is phase-change constant-temperature layer, and 4 is layer of pharmaceutical composition, 5 be from Type paper.
Specific embodiment
Specific embodiment of the invention is described in further detail with embodiment below:
Embodiment one:
Referring to Fig. 1~Fig. 2, a kind of intelligent constant-temperature hot compress paste, by pressure sensitive adhesive patch 1, heater 2, phase-change constant-temperature layer 3, medicine Compositions layer 4 and release liners 5 are constituted, and pressure sensitive adhesive patch 1, heater 2, phase-change constant-temperature layer 3, medicine are arranged in order from the bottom to top Composition layer 4 and release liners 5, heater 2 is bonded in the middle of pressure sensitive adhesive patch 1 in island shape, and both sides or surrounding have in wing To help be fixed in skin, there are phase-change constant-temperature layer 3, described phase-change constant-temperature 3 preparation method of layer in the surface of heater 2 for pressure sensitive adhesive patch 1 It is the SBS resins 2g and 300 DEG C of fraction atoleine 10g for taking model YH-801, is heated to 160 DEG C and is melt into uniform liquid Soft forming agent;The polyethylene glycol for taking the mean molecule quantity 100 of 42 DEG C of transformation temperature is phase transition agent 10g, is heated to 60 DEG C and melts Change, agent mixing is then contained with the particulate of the swelling perlite powder 3g of 70 mesh granularities, be subsequently poured into soft forming agent mixing equal It is even, the upper surface of heater 2 is coated on, thickness is 1mm, i.e. phase-change constant-temperature layer 3;Medicine is superimposed with again on 3 surface of phase-change constant-temperature layer Composition layer 4, layer of pharmaceutical composition 4 is prepared in the following manner:Greater celandine ethanol extract 20g is taken, adds polyacrylic acid water-soluble Liquid 6.5g, glycerine 10g are mixed, and are added the solution mixed by aluminium chloride 0.8g, citric acid 0.8g, water 66.9g and are stirred, and are applied Be distributed in phase-change constant-temperature layer 3 surfaces thickness 0.5mm, in described layer of pharmaceutical composition 4 covering release liners 5 intelligent constant-temperature hot compress Patch.
Embodiment two:
Referring to Fig. 1~Fig. 2, a kind of intelligent constant-temperature hot compress paste, by pressure sensitive adhesive patch 1, heater 2, phase-change constant-temperature layer 3, medicine Compositions layer 4 and release liners 5 are constituted, and pressure sensitive adhesive patch 1, heater 2, phase-change constant-temperature layer 3, medicine are arranged in order from the bottom to top Composition layer 4 and release liners 5, heater 2 is bonded in the middle of pressure sensitive adhesive patch 1 in island shape, and both sides or surrounding have in wing To help be fixed in skin, there are phase-change constant-temperature layer 3, the system of described phase-change constant-temperature layer 3 in the surface of heater 2 for pressure sensitive adhesive patch 1 Method be take model YH-792 SBS resins 1.6g and atoleine 10g be heated to 160 DEG C be melt into uniform liquid it is soft Property forming agent;The polyethylene glycol 20g for taking the mean molecule quantity 100 of 42 DEG C of transformation temperature makees phase transition agent, is heated to 60 DEG C of fusings, then Agent mixing is contained with the particulate of 3g gas phase of white carbon black, unnecessary phase transition agent is filtered with gauze, be subsequently poured into soft forming agent mixing equal It is even, the upper surface of heater 2 is coated on, thickness is 1.5m, i.e. phase-change constant-temperature layer 3;Medicine is superimposed with again on 3 surface of phase-change constant-temperature layer Composition layer 4, layer of pharmaceutical composition 4 is prepared in the following manner:Greater celandine ethanol extract 20g is taken, adds polyacrylic acid water-soluble Liquid 6.5g, glycerine 10g are mixed, and are added the solution mixed by aluminium chloride 0.8g, citric acid 0.8g, water 66.9g and are stirred, and are applied Be distributed in phase-change constant-temperature layer 3 surfaces thickness 0.5mm, in described layer of pharmaceutical composition 4 covering release liners 5 intelligent constant-temperature hot compress Patch.
Embodiment three:
Referring to Fig. 1~Fig. 2, a kind of intelligent constant-temperature hot compress paste, by pressure sensitive adhesive patch 1, heater 2, phase-change constant-temperature layer 3, medicine Compositions layer 4 and release liners 5 are constituted, and pressure sensitive adhesive patch 1, heater 2, phase-change constant-temperature layer 3, medicine are arranged in order from the bottom to top Composition layer 4 and release liners 5, heater 2 is bonded in the middle of pressure sensitive adhesive patch 1 in island shape, and both sides or surrounding have in wing To help be fixed in skin, there are phase-change constant-temperature layer 3, the system of described phase-change constant-temperature layer 3 in the surface of heater 2 for pressure sensitive adhesive patch 1 Method be take model YH-802 SBS resins 1g and atoleine 10g be heated to 160 DEG C be melt into uniform liquid it is flexible Forming agent;The polyethylene glycol for taking the mean molecule quantity 100 of 42 DEG C of transformation temperature makees phase transition agent 20g, is heated to 60 DEG C of fusings, Ran Houhe The particulate of 10g montmorillonites contains agent mixing, and unnecessary phase transition agent is filtered with gauze, is subsequently poured into soft forming agent and is well mixed, and applies In heater upper surface, thickness is 1mm to cloth, i.e. phase-change constant-temperature layer 3;Pharmaceutical composition is superimposed with again on 3 surface of phase-change constant-temperature layer Layer 4, layer of pharmaceutical composition 4 is prepared in the following manner:Greater celandine ethanol extract 20g is taken, polyacrylic acid aqueous solution 6.5g is added, Glycerine 10g is mixed, and is added the solution mixed by aluminium chloride 0.8g, citric acid 0.8g, water 66.9g and is stirred, and coats phase Become the surface thickness 0.5mm of thermostat layer 3, in described layer of pharmaceutical composition 4 covering release liners 5 intelligent constant-temperature hot compress paste.
The embodiment of the above, simply presently preferred embodiments of the present invention, not limits practical range of the invention, Therefore the equivalent change or modification that all constructions according to described in the scope of the claims of the present invention, feature and principle are done, this hair all should be included in In bright claim.

Claims (8)

1. a kind of intelligent constant-temperature hot compress paste, it is characterised in that by pressure sensitive adhesive patch (1), heater (2), phase-change constant-temperature layer (3), Layer of pharmaceutical composition (4) and release liners(5)Composition, is arranged in order pressure sensitive adhesive patch (1), heater (2), phase transformation perseverance from the bottom to top Warm layer (3), layer of pharmaceutical composition (4) and release liners(5), described heater(2)It is described positioned at the centre of pressure sensitive adhesive patch Phase-change constant-temperature layer(3)Positioned at heater (2) surface, phase-change constant-temperature layer(3)Agent and flexible formation agent are contained by phase transition agent, particulate Composition, by weight, its proportioning contains agent 8~25%, flexible formation agent 18~48% for phase transition agent 40~60%, particulate, described Flexible formation agent be SBS resins and 200~400 DEG C of fraction atoleines, SBS resins and 200~400 DEG C of fraction atoleines With 1:(5~10)Proportions oil-base gel or hot-fusible pressure-sensitive adhesive, the weight sum that phase transition agent contains agent with particulate is soft 1~3 times of the weight of property forming agent.
2. intelligent constant-temperature hot compress paste according to claim 1, it is characterised in that described pressure sensitive adhesive patch (1) is using pressure Quick glue coated and be made on non-woven fabrics.
3. intelligent constant-temperature hot compress paste according to claim 1, it is characterised in that described phase-change constant-temperature layer (3) coating or It is bonded in the surface of heater (2).
4. intelligent constant-temperature hot compress paste according to claim 3, it is characterised in that described phase-change constant-temperature layer(3)In phase Become polyethylene glycol of the agent from mean molecule quantity 800~1200, transformation temperature is at 40 DEG C~45 DEG C.
5. intelligent constant-temperature hot compress paste according to claim 4, it is characterised in that the optimal transformation temperature of described phase transition agent is 43℃。
6. intelligent constant-temperature hot compress paste according to claim 1, it is characterised in that described particulate contains agent expanded vermiculite Powder, swelling perlite powder, expanded graphite, montmorillonite, activated carbon, gas phase of white carbon black one kind therein, particulate contain agent and phase transformation Agent prepare weight be than scope(1~7):(7~1)Between.
7. intelligent constant-temperature hot compress paste according to claim 1, it is characterised in that described layer of pharmaceutical composition(4)By weight Amount part be calculated as 10~20 parts of greater celandine ethanol extract, 2.4~8.5 parts of polyacrylic acid, 10~20 parts of glycerine, aluminium chloride 0.3~ 0.9 part, 0.3~0.9 part of citric acid, 57~70 parts of water is obtained.
8. intelligent constant-temperature hot compress paste according to claim 1, it is characterised in that described heater(2)In island morpheme in Pressure sensitive adhesive patch(1)Centre, heater(2)It is warm patch.
CN201510638008.5A 2015-09-30 2015-09-30 Intelligent constant-temperature hot compress paste Active CN105147445B (en)

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CN105596141A (en) * 2016-01-28 2016-05-25 广东工业大学 Disposable self-heating health care patch having low-temperature solid-solid phase transition temperature control characteristic
CN106511469A (en) * 2016-12-28 2017-03-22 河南省超亚医药器械有限公司 Medicated ironing patch for treating dysmenorrhea and preparation method of medicated ironing patch for treating dysmenorrhea
CN107149521A (en) * 2017-06-29 2017-09-12 赵岩 A kind of medical self-heating type far infrared resonance wave patch and preparation method thereof
CN108013972B (en) * 2017-12-25 2023-07-14 北京昊坤康源医疗科学技术发展有限责任公司 Postoperative incision is applied ointment or plaster
CN108542589A (en) * 2018-05-22 2018-09-18 上海暖友实业有限公司 Constant temperature spontaneous heating utensil containing phase-change microcapsule
CN109589203A (en) * 2018-10-22 2019-04-09 清华大学 The heating paste of temperature control film and the spontaneous hotting mask of constant temperature based on organic phase-change
TWI725812B (en) * 2019-01-08 2021-04-21 友睦科技股份有限公司 Far infrared fomentation device
CN112451201B (en) * 2020-11-26 2021-06-08 王兴伟 Self-heating patch for pediatrics and preparation method thereof
CN113730088A (en) * 2021-06-11 2021-12-03 郑州市新视明科技工程有限公司 Thin-sheet type self-heating body eye patch and preparation process thereof
CN114712075A (en) * 2022-03-17 2022-07-08 中国人民解放军总医院第八医学中心 Phase-change energy-storage type ultrathin self-heating application and preparation method

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CN103183862A (en) * 2013-03-22 2013-07-03 中国科学院山西煤炭化学研究所 High-thermal-conductivity phase-change composite material and preparation process thereof
CN204207916U (en) * 2014-09-12 2015-03-18 洛阳民华生物科技有限公司 Novel cervical vertebra pastes
CN204219138U (en) * 2014-11-04 2015-03-25 青岛沃普艾斯日用品有限公司 Temperature control warm pastes

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CN102516948A (en) * 2011-12-06 2012-06-27 辽宁科隆精细化工股份有限公司 Process for synthesizing polyethylene glycol (PEG) phase change thermal insulation material
CN103183862A (en) * 2013-03-22 2013-07-03 中国科学院山西煤炭化学研究所 High-thermal-conductivity phase-change composite material and preparation process thereof
CN204207916U (en) * 2014-09-12 2015-03-18 洛阳民华生物科技有限公司 Novel cervical vertebra pastes
CN204219138U (en) * 2014-11-04 2015-03-25 青岛沃普艾斯日用品有限公司 Temperature control warm pastes

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