CN105147445A - Intelligent constant-temperature hot-compressing patch - Google Patents

Intelligent constant-temperature hot-compressing patch Download PDF

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Publication number
CN105147445A
CN105147445A CN201510638008.5A CN201510638008A CN105147445A CN 105147445 A CN105147445 A CN 105147445A CN 201510638008 A CN201510638008 A CN 201510638008A CN 105147445 A CN105147445 A CN 105147445A
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temperature
constant
layer
agent
phase
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CN201510638008.5A
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CN105147445B (en
Inventor
赵雪林
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Henan Super Asia Medical Equipment Co ltd
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HENAN SUPER ASIA MEDICAL EQUIPMENT CO Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/02Compresses or poultices for effecting heating or cooling
    • A61F7/03Compresses or poultices for effecting heating or cooling thermophore, i.e. self-heating, e.g. using a chemical reaction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/02Compresses or poultices for effecting heating or cooling
    • A61F2007/0261Compresses or poultices for effecting heating or cooling medicated

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  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Thermal Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Thermotherapy And Cooling Therapy Devices (AREA)

Abstract

An intelligent constant-temperature hot-compressing patch consists of a pressure-sensitive adhesive fabric, a heating body, a phase change constant-temperature layer, a medicine composition layer and release paper, wherein the pressure-sensitive adhesive fabric, the heating body, the phase change constant-temperature layer, the medicine composition layer and the release paper are sequentially arranged from bottom to top, the heating body is located in the middle of the pressure-sensitive adhesive fabric, and the phase change constant-temperature layer is located on the surface of the heating body and is prepared from, by weight 40-60% of phase change agent, 8-25% of particle entrapment agent and 18-48% of flexible forming agent. The intelligent constant-temperature hot-compressing patch can achieve automatic constancy, enables the temperature approaching the skin temperature to be kept constant and provides higher safety guarantee by serving as a medical product attached to the skin for usage.

Description

Intelligent constant-temperature hot application
Technical field
The present invention relates to a kind of medical supplies, for meridian point thermostimulation, particularly a kind of intelligent constant-temperature hot application.
Background technology
Chemical heating agent for making self-heating moxibustion, hot application one class medical products has many patents.As CN201410734521 hot application Press pin patent, exothermic mixture bag and thumb-tack needle for subcutaneous embedding are combined the self-heating moxibustion being designed to be with thumb-tack needle for subcutaneous embedding and pastes.Energy dredging the meridian of the present invention, QI and blood regulating, thus reach and rouse oneself yang-energy, blood circulation promoting, dispel cold-evil, improve therapeutic efficiency; CN201420684248 devises the moxibustion of medicated magnet self-heating from hot body, by pad pasting regulation heating temperature in conjunction with medicament magnetic material and chemistry; The ceramic blister layer effect on human body that CN201410329768 constant temperature spontaneous heating moxibustion is pasted by being combined with magnetic material from hot body plays hot compress effect.It is feasible that these schemes meet predetermined heating temp under standard using state, but to be usually affixed on when human body uses ambient temperature difference and to wear medicated clothing how much all affect its heater temperature, and the temperature of performance and preset temperature are discrepant.
Summary of the invention
The invention provides one and can improve its safety, eliminate unexpected injury, the intelligent constant-temperature hot application of intelligent constant-temperature can be realized.
For solving the problems of the technologies described above, technical scheme of the present invention is:
A kind of intelligent constant-temperature hot application, be made up of pressure sensitive adhesive patch, heater, phase-change constant-temperature layer, layer of pharmaceutical composition and release paper, be arranged in order pressure sensitive adhesive patch, heater, phase-change constant-temperature layer, layer of pharmaceutical composition and release paper from the bottom to top, described heater is positioned at the centre of pressure sensitive adhesive patch, described phase-change constant-temperature layer is positioned at heater surface, phase-change constant-temperature layer is made up of phase transition agent, microgranule bag supporting agent and flexible formation agent, by weight, its proportioning is phase transition agent 40 ~ 60%, microgranule bag supporting agent 8 ~ 25%, flexible formation agent 18 ~ 48%.
Further, described pressure sensitive adhesive patch adopts pressure sensitive adhesive to coat on non-woven fabrics and makes.
Further, described phase-change constant-temperature layer applies or is bonded in the surface of heater.
Further, the phase transition agent in described phase-change constant-temperature layer selects the Polyethylene Glycol of mean molecule quantity 800 ~ 1200, and transformation temperature is at 40 DEG C ~ 45 DEG C.
Further, the optimum transformation temperature of described phase transition agent is 43 DEG C.
Further, described microgranule bag supporting agent expanded vermiculite powder, swelling perlite powder, expanded graphite, montorillonite clay, activated carbon, gas phase White Carbon black one wherein, the weight ratio of microgranule bag supporting agent and phase transition agent preparation is (1 ~ 4): between (4 ~ 1).
Further, described flexible formation agent is SBS resin and 200 ~ 400 DEG C of fraction liquid paraffin, SBS resin and 200 ~ 400 DEG C of fraction liquid paraffin are with 1:(5 ~ 10) the oil-base gel of proportions or hot-fusible pressure-sensitive adhesive, the weight sum of phase transition agent and microgranule bag supporting agent is 1 ~ 3 times of the weight of flexible formation agent.
Further, described layer of pharmaceutical composition count by weight Herba Chelidonii ethanol extraction 10 ~ 20 parts, polyacrylic acid 2.4 ~ 8.5 parts, glycerol 10 ~ 20 parts, 0.3 ~ 0.9 part, aluminum chloride, citric acid 0.3 ~ 0.9 part, 57 ~ 70 parts, water obtain.
Further, described heater be island morpheme in the centre of pressure sensitive adhesive patch, heater pastes for warm.
The invention has the beneficial effects as follows:
Structurally, although general self-heating paste application can reach under normal service conditions by accurately controlling to penetrate air, temperature-controllable is built in set point, but it is as excessive in ambient temperature difference or surface covering is blocked up, namely temperature may be made to exceed set point by skin burn, intelligent constant-temperature hot application of the present invention increases phase-change thermal storage structure on existing self-heating paste application technical scheme basis, absorb heat higher than during transformation temperature in temperature, in temperature lower than heat release during transformation temperature, realize intelligent constant-temperature, Polyethylene Glycol latent heat of phase change is 140-170kJ/kg, iron powder heat production 69.5kJ/kg, as heater has the total heat production of iron powder 10g to be 695J, the highest heating temp of heater standard is controlled within 48 DEG C, so 1.5g Polyethylene Glycol enthalpy of phase change 210J accounts for total amount of heat about 30% and can reach the temperature remained constant that automatic flat perseverance makes skin-proximal, higher safety guarantee is had as the medical product being close to skin use.
Temperature test synopsis:
_________________________________________________________
Non-constant temperature sample test maximum temperature constant temperature sample test maximum temperature
151.3℃143.7℃
246.1℃243.5℃
344.0℃343.7℃
444.7℃444.0℃
550.4℃543.3℃
_________________________________________________________。
Accompanying drawing explanation
Fig. 1 is the structural representation of a kind of intelligent constant-temperature hot application of the present invention.
Fig. 2 is the structural representation overlooked of a kind of intelligent constant-temperature hot application of the present invention.
Sequence number in figure: 1 is pressure sensitive adhesive patch, 2 is heater, and 3 is phase-change constant-temperature layer, and 4 is layer of pharmaceutical composition, and 5 is release paper.
Detailed description of the invention
With embodiment, the specific embodiment of the present invention is described in further detail below:
Embodiment one:
See Fig. 1 ~ Fig. 2, a kind of intelligent constant-temperature hot application, by pressure sensitive adhesive patch 1, heater 2, phase-change constant-temperature layer 3, layer of pharmaceutical composition 4 and release paper 5 form, be arranged in order pressure sensitive adhesive patch 1 from the bottom to top, heater 2, phase-change constant-temperature layer 3, layer of pharmaceutical composition 4 and release paper 5, heater 2 is bonded in island shape in the middle of pressure sensitive adhesive patch 1, both sides or surrounding have the pressure sensitive adhesive patch 1 in wing to help to fix at skin, there is a phase-change constant-temperature layer 3 on heater 2 surface, described phase-change constant-temperature layer 3 method for making is, get SBS resin 2g and the 300 DEG C of fraction liquid paraffin 10g that model is YH-801, be heated to 160 DEG C be melt into uniform liquid soft forming agent, the Polyethylene Glycol getting the mean molecule quantity 100 of transformation temperature 42 DEG C is phase transition agent 10g, be heated to 60 DEG C of fusings, the microgranule bag supporting agent mixing of the swelling perlite powder 3g of then with 70 order granularities, then soft forming agent mix homogeneously is poured into, be coated on heater 2 upper surface, thickness is 1mm, i.e. phase-change constant-temperature layer 3, layer of pharmaceutical composition 4 is superimposed with again on phase-change constant-temperature layer 3 surface, layer of pharmaceutical composition 4 is prepared in the following manner: get Herba Chelidonii ethanol extraction 20g, add polyacrylic acid aqueous solution 6.5g, glycerol 10g mixes, add the solution stirring mixed by aluminum chloride 0.8g, citric acid 0.8g, water 66.9g more even, coat the surperficial thick 0.5mm of phase-change constant-temperature layer 3, described layer of pharmaceutical composition 4 covers release paper 5 intelligent constant-temperature hot application.
Embodiment two:
See Fig. 1 ~ Fig. 2, a kind of intelligent constant-temperature hot application, by pressure sensitive adhesive patch 1, heater 2, phase-change constant-temperature layer 3, layer of pharmaceutical composition 4 and release paper 5 form, be arranged in order pressure sensitive adhesive patch 1 from the bottom to top, heater 2, phase-change constant-temperature layer 3, layer of pharmaceutical composition 4 and release paper 5, heater 2 is bonded in island shape in the middle of pressure sensitive adhesive patch 1, both sides or surrounding have the pressure sensitive adhesive patch 1 in wing to help to fix at skin, there is a phase-change constant-temperature layer 3 on heater 2 surface, the method for making of described phase-change constant-temperature layer 3 is, get SBS resin 1.6g that model is YH-792 and liquid paraffin 10g be heated to 160 DEG C be melt into uniform liquid flexible formation agent, the Polyethylene Glycol 20g getting the mean molecule quantity 100 of transformation temperature 42 DEG C makes phase transition agent, be heated to 60 DEG C of fusings, then mix with the microgranule bag supporting agent of 3g gas phase White Carbon black, with the unnecessary phase transition agent of gauze filtering, then soft forming agent mix homogeneously is poured into, be coated on heater 2 upper surface, thickness is 1.5m, i.e. phase-change constant-temperature layer 3, layer of pharmaceutical composition 4 is superimposed with again on phase-change constant-temperature layer 3 surface, layer of pharmaceutical composition 4 is prepared in the following manner: get Herba Chelidonii ethanol extraction 20g, add polyacrylic acid aqueous solution 6.5g, glycerol 10g mixes, add the solution stirring mixed by aluminum chloride 0.8g, citric acid 0.8g, water 66.9g more even, coat the surperficial thick 0.5mm of phase-change constant-temperature layer 3, described layer of pharmaceutical composition 4 covers release paper 5 intelligent constant-temperature hot application.
Embodiment three:
See Fig. 1 ~ Fig. 2, a kind of intelligent constant-temperature hot application, by pressure sensitive adhesive patch 1, heater 2, phase-change constant-temperature layer 3, layer of pharmaceutical composition 4 and release paper 5 form, be arranged in order pressure sensitive adhesive patch 1 from the bottom to top, heater 2, phase-change constant-temperature layer 3, layer of pharmaceutical composition 4 and release paper 5, heater 2 is bonded in island shape in the middle of pressure sensitive adhesive patch 1, both sides or surrounding have the pressure sensitive adhesive patch 1 in wing to help to fix at skin, there is a phase-change constant-temperature layer 3 on heater 2 surface, the method for making of described phase-change constant-temperature layer 3 is, get SBS resin 1g that model is YH-802 and liquid paraffin 10g be heated to 160 DEG C be melt into uniform liquid flexible formation agent, phase transition agent 20g made by the Polyethylene Glycol getting the mean molecule quantity 100 of transformation temperature 42 DEG C, be heated to 60 DEG C of fusings, then mix with the microgranule bag supporting agent of 10g montorillonite clay, with the unnecessary phase transition agent of gauze filtering, then soft forming agent mix homogeneously is poured into, be coated on heater upper surface, thickness is 1mm, i.e. phase-change constant-temperature layer 3, layer of pharmaceutical composition 4 is superimposed with again on phase-change constant-temperature layer 3 surface, layer of pharmaceutical composition 4 is prepared in the following manner: get Herba Chelidonii ethanol extraction 20g, add polyacrylic acid aqueous solution 6.5g, glycerol 10g mixes, add the solution stirring mixed by aluminum chloride 0.8g, citric acid 0.8g, water 66.9g more even, coat the surperficial thick 0.5mm of phase-change constant-temperature layer 3, described layer of pharmaceutical composition 4 covers release paper 5 intelligent constant-temperature hot application.
The embodiment of the above, just preferred embodiment of the present invention, and unrestricted practical range of the present invention, therefore all equivalences done according to structure, feature and the principle described in the scope of the claims of the present invention change or modify, and all should be included in the present patent application the scope of the claims.

Claims (9)

1. an intelligent constant-temperature hot application, it is characterized in that, by pressure sensitive adhesive patch (1), heater (2), phase-change constant-temperature layer (3), layer of pharmaceutical composition (4) and release paper (5) composition, be arranged in order pressure sensitive adhesive patch (1) from the bottom to top, heater (2), phase-change constant-temperature layer (3), layer of pharmaceutical composition (4) and release paper (5), described heater (2) is positioned at the centre of pressure sensitive adhesive patch, described phase-change constant-temperature layer (3) is positioned at heater (2) surface, phase-change constant-temperature layer (3) is by phase transition agent, microgranule bag supporting agent and flexible formation agent composition, by weight, its proportioning is phase transition agent 40 ~ 60%, microgranule bag supporting agent 8 ~ 25%, flexible formation agent 18 ~ 48%.
2. intelligent constant-temperature hot application according to claim 1, is characterized in that, described pressure sensitive adhesive patch (1) adopts pressure sensitive adhesive to coat on non-woven fabrics and makes.
3. intelligent constant-temperature hot application according to claim 1, is characterized in that, described phase-change constant-temperature layer (3) applies or be bonded in the surface of heater (2).
4. intelligent constant-temperature hot application according to claim 3, is characterized in that, the phase transition agent in described phase-change constant-temperature layer (3) selects the Polyethylene Glycol of mean molecule quantity 800 ~ 1200, and transformation temperature is at 40 DEG C ~ 45 DEG C.
5. intelligent constant-temperature hot application according to claim 4, is characterized in that, the optimum transformation temperature of described phase transition agent is 43 DEG C.
6. intelligent constant-temperature hot application according to claim 1, it is characterized in that, described microgranule bag supporting agent expanded vermiculite powder, swelling perlite powder, expanded graphite, montorillonite clay, activated carbon, gas phase White Carbon black one wherein, the weight ratio of microgranule bag supporting agent and phase transition agent preparation is (1 ~ 7): between (7 ~ 1).
7. intelligent constant-temperature hot application according to claim 1, it is characterized in that, described flexible formation agent is SBS resin and 200 ~ 400 DEG C of fraction liquid paraffin, SBS resin and 200 ~ 400 DEG C of fraction liquid paraffin are with 1:(5 ~ 10) the oil-base gel of proportions or hot-fusible pressure-sensitive adhesive, the weight sum of phase transition agent and microgranule bag supporting agent is 1 ~ 3 times of the weight of flexible formation agent.
8. intelligent constant-temperature hot application according to claim 1, it is characterized in that, described layer of pharmaceutical composition (4) count by weight Herba Chelidonii ethanol extraction 10 ~ 20 parts, polyacrylic acid 2.4 ~ 8.5 parts, glycerol 10 ~ 20 parts, 0.3 ~ 0.9 part, aluminum chloride, citric acid 0.3 ~ 0.9 part, 57 ~ 70 parts, water obtain.
9. intelligent constant-temperature hot application according to claim 1, is characterized in that, described heater (2) is in the centre of island morpheme in pressure sensitive adhesive patch (1), and heater (2) pastes for warm.
CN201510638008.5A 2015-09-30 2015-09-30 Intelligent constant-temperature hot compress paste Active CN105147445B (en)

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Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105596141A (en) * 2016-01-28 2016-05-25 广东工业大学 Disposable self-heating health care patch having low-temperature solid-solid phase transition temperature control characteristic
CN106511469A (en) * 2016-12-28 2017-03-22 河南省超亚医药器械有限公司 Medicated ironing patch for treating dysmenorrhea and preparation method of medicated ironing patch for treating dysmenorrhea
CN107149521A (en) * 2017-06-29 2017-09-12 赵岩 A kind of medical self-heating type far infrared resonance wave patch and preparation method thereof
CN108013972A (en) * 2017-12-25 2018-05-11 武汉明康医疗器械有限公司 A kind of incision applicator for postoperation
CN108542589A (en) * 2018-05-22 2018-09-18 上海暖友实业有限公司 Constant temperature spontaneous heating utensil containing phase-change microcapsule
CN109589203A (en) * 2018-10-22 2019-04-09 清华大学 The heating paste of temperature control film and the spontaneous hotting mask of constant temperature based on organic phase-change
CN112451201A (en) * 2020-11-26 2021-03-09 郑程程 Self-heating patch for pediatrics and preparation method thereof
TWI725812B (en) * 2019-01-08 2021-04-21 友睦科技股份有限公司 Far infrared fomentation device
CN113730088A (en) * 2021-06-11 2021-12-03 郑州市新视明科技工程有限公司 Thin-sheet type self-heating body eye patch and preparation process thereof
CN114712075A (en) * 2022-03-17 2022-07-08 中国人民解放军总医院第八医学中心 Phase-change energy-storage type ultrathin self-heating application and preparation method

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002204833A (en) * 2001-01-10 2002-07-23 Sadahiro Ohinata Heat generating body and heat generating body housing bag
CN102516948A (en) * 2011-12-06 2012-06-27 辽宁科隆精细化工股份有限公司 Process for synthesizing polyethylene glycol (PEG) phase change thermal insulation material
CN103183862A (en) * 2013-03-22 2013-07-03 中国科学院山西煤炭化学研究所 High-thermal-conductivity phase-change composite material and preparation process thereof
CN204207916U (en) * 2014-09-12 2015-03-18 洛阳民华生物科技有限公司 Novel cervical vertebra pastes
CN204219138U (en) * 2014-11-04 2015-03-25 青岛沃普艾斯日用品有限公司 Temperature control warm pastes

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002204833A (en) * 2001-01-10 2002-07-23 Sadahiro Ohinata Heat generating body and heat generating body housing bag
CN102516948A (en) * 2011-12-06 2012-06-27 辽宁科隆精细化工股份有限公司 Process for synthesizing polyethylene glycol (PEG) phase change thermal insulation material
CN103183862A (en) * 2013-03-22 2013-07-03 中国科学院山西煤炭化学研究所 High-thermal-conductivity phase-change composite material and preparation process thereof
CN204207916U (en) * 2014-09-12 2015-03-18 洛阳民华生物科技有限公司 Novel cervical vertebra pastes
CN204219138U (en) * 2014-11-04 2015-03-25 青岛沃普艾斯日用品有限公司 Temperature control warm pastes

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105596141A (en) * 2016-01-28 2016-05-25 广东工业大学 Disposable self-heating health care patch having low-temperature solid-solid phase transition temperature control characteristic
CN106511469A (en) * 2016-12-28 2017-03-22 河南省超亚医药器械有限公司 Medicated ironing patch for treating dysmenorrhea and preparation method of medicated ironing patch for treating dysmenorrhea
CN107149521A (en) * 2017-06-29 2017-09-12 赵岩 A kind of medical self-heating type far infrared resonance wave patch and preparation method thereof
CN108013972A (en) * 2017-12-25 2018-05-11 武汉明康医疗器械有限公司 A kind of incision applicator for postoperation
CN108542589A (en) * 2018-05-22 2018-09-18 上海暖友实业有限公司 Constant temperature spontaneous heating utensil containing phase-change microcapsule
CN109589203A (en) * 2018-10-22 2019-04-09 清华大学 The heating paste of temperature control film and the spontaneous hotting mask of constant temperature based on organic phase-change
TWI725812B (en) * 2019-01-08 2021-04-21 友睦科技股份有限公司 Far infrared fomentation device
CN112451201A (en) * 2020-11-26 2021-03-09 郑程程 Self-heating patch for pediatrics and preparation method thereof
CN112451201B (en) * 2020-11-26 2021-06-08 王兴伟 Self-heating patch for pediatrics and preparation method thereof
CN113730088A (en) * 2021-06-11 2021-12-03 郑州市新视明科技工程有限公司 Thin-sheet type self-heating body eye patch and preparation process thereof
CN114712075A (en) * 2022-03-17 2022-07-08 中国人民解放军总医院第八医学中心 Phase-change energy-storage type ultrathin self-heating application and preparation method

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