CN105012614A

CN105012614A - External-use traditional Chinese medicine for treating knee osteoarthritis and nursing method

Info

Publication number: CN105012614A
Application number: CN201510399884.7A
Authority: CN
Inventors: 刘庆娥
Original assignee: Individual
Current assignee: Individual
Priority date: 2015-06-29
Filing date: 2015-06-29
Publication date: 2015-11-04

Abstract

The invention discloses an external-use traditional Chinese medicine for treating knee osteoarthritis. According to traditional Chinese medicine, retrogressive osteoarthritis of knee joint is listed in the category of heumatism. It is considered that at the middle age of people, deficiency of liver and kidney, disorder of Qi and blood and mascular malnutrition will happen, and trauma, fatigue and wind-cold-wetness evil will lead to congestion of fluid-retention, obstructed venation and mascular malnutrition so as to cause diseases. Therefore, traditional Chinese medicines including root of Japanese Glorybower, root or leaf of Pilose Triumfetta, henry clematis root, scarlet kadsura root, all grass of Highstalk Razorsedge, herb of Laciniate Blumea, bark of Common Schefflera, root of Veined Inula, herb of Mandarin Clematis, Chinese forgetmenot root, indigofera mengtzeana and root of Chinese Clovershrub are decocted with water to obtain a decoction of herbal medicines. Through clinical tests, total effective rate reaches 95.0%, and clinical therapeutic effects are remarkable.

Description

A kind of external traditional Chinese medicinal application and care method for the treatment of knee joint osseous arthritis

Technical field

The present invention relates to a kind of Chinese medicine composition, particularly relate to a kind of external traditional Chinese medicinal application for the treatment of knee joint osseous arthritis.

Background technology

Knee joint osseous arthritis (osteoarthritis, OA) refers to due to knee cartilage degeneration, hyperosteogeny and the chronic osteoarthrosis illness of one caused, and is also called gonarthrosis, degenerative osteoarthritis and osseous arthritis etc.Primary disease is multiple is born in middle-aged and elderly people, also adolescence can occur; Can one-sidedly fall ill, also can bilateral morbidity.Knee joint OA refers to the thin-skinned ostosis constitutional of knee joint endoprosthesis or secondary degeneration and structure disturbance, strip off with subchondral bone matter hypertrophy, cartilage, thus joint is destroyed gradually, deformity, a kind of degenerative disease of final generation knee joint disorders, general long-term posture is bad, bear a heavy burden firmly, overweight, chronic strain is all the cause of disease causing knee joint OA, the misery that OA causes and the disabled life quality seriously damaging patient, and become one of serious social economical burden that current social faces.Along with China's population progressively enters the aging epoch, estimate that the sickness rate of OA also can be more and more higher.The object of osteoarthritis treatment is alleviation arthralgia, improves function and rebuild impaired cartilage and bone structure, but at present from doctor trained in Western medicine, still lack the reliable medicine that can achieve the goal, even if only by relief of symptoms, improve for the purpose of function, also lack the non-operative treatment of better efficacy, less adverse effect.Similarly, operative treatment (as arthrodesis, joint replacement) is no matter price or technology all can only be carried out in small number of patients.Traditional medicine synthetic therapy is current comparatively ideal Therapeutic Method.Most treatment is inflammation by alleviating, eliminating joint and surrounding tissue thereof and reaches alleviating pain, improves the object of function.Clinical practice proves, the external application of Chinese medicine has unique curative effect to osteoarthritis.

Summary of the invention

The object of this invention is to provide a kind of external traditional Chinese medicinal application for the treatment of knee joint osseous arthritis.The traditional Chinese medical science lists knee joint degenerative osteoarthritis in " rheumatism involving the bone " category.Think people in middle age, deficiency of the liver and kindey, disorder of QI and blood, muscles and bones is lost it and is moistened foster, in addition wound, strain and the damp that is affected by the cold, make to stop in the expectorant stasis of blood, venation is obstructed, and muscles and bones mistake is supported and fallen ill.

The object of the invention is to be achieved through the following technical solutions, the external traditional Chinese medicinal application of this treatment knee joint osseous arthritis is made up of the Chinese medicine of following weight portion: Radix Ixorae Chinensis 30-60 part, Radix Seu Folium Triumfettae Pilosae 3-9 part, Radix Clematidis Henryi 3-6 part, Radix Kadsurae Coccineae 15-30 part, Herba Scleriae Terrestris 18-30 part, Herba Blumeae Laciniatae 15-35 part, Cortex schefflerae octophyllae 9-15 part, Radix Inulae Nervosae 6-15 part, Herba Clematidis Lasiandrae 9-18 part, Rhizoma seu Herba Elatostematis stewardii 10-25 part, Indigofera mentzeana Craib 6-9 part, Radix Campylotropis Macrocarpae 6-12 part.

Preferably, Radix Ixorae Chinensis 45 parts, Radix Seu Folium Triumfettae Pilosae 6 parts, Radix Clematidis Henryi 5 parts, Radix Kadsurae Coccineae 22 parts, Herba Scleriae Terrestris 24 parts, the Herba Blumeae Laciniatae 25 parts, Cortex schefflerae octophyllae 12 parts, Radix Inulae Nervosae 10 parts, Herba Clematidis Lasiandrae 23 parts, Rhizoma seu Herba Elatostematis stewardii 18 parts, Indigofera mentzeana Craib 7 parts, Radix Campylotropis Macrocarpae 9 parts.

It is for subsequent use that above-mentioned Chinese medicine grinding Mel furnishing pasty state is made ointment by preparation method.

Fang Zhong: the pain relieving of Radix Ixorae Chinensis sending down the abnormal ascending QI, promoting blood circulation to remove obstruction in the collateral; Radix Seu Folium Triumfettae Pilosae promoting flow of QI and blood; Radix Clematidis Henryi promoting the circulation of QI to relieve pain, anti inflammatory blood quickening; Radix Kadsurae Coccineae promoting the circulation of QI to relieve pain, dissipating blood stasis for subsidence of swelling, dispelling, collateral-activating; Herba Scleriae Terrestris is except rheumatism, the meridian dredging; To gallop along on horseback phoenix expelling wind and removing dampness, dredge the meridian passage; Cortex schefflerae octophyllae expelling wind and removing dampness, loose swollen, dissipating blood stasis; Radix Inulae Nervosae wind-damp dispelling, the meridian dredging, removing food stagnancy, pain relieving; Herba Clematidis Lasiandrae relaxing muscles and tendons to promote blood circulation, damp-clearing pain-relieving; Rhizoma seu Herba Elatostematis stewardii relaxing muscles and tendons and activating QI and blood in the collateral, promoting tissue regeneration by removing blood stasis; Indigofera mentzeana Craib relaxing muscles and tendons and activating QI and blood in the collateral, analgesia, antiinflammatory; Radix Campylotropis Macrocarpae relaxing muscles and tendons and activating QI and blood in the collateral.

Clinical data

The routine case of physical data 122 is clinic case, meets diagnostic criteria and inclusive criteria.Be divided into treatment group and each 61 examples of matched group at random, man 24 example in treatment group, female 37 example; 51 years old ~ 68 years old age; Wherein single knee joint person 38 example, two knee joint person 23 example, disease time 6 months to 8 years, average 4.5 years.Man 32 example in matched group, female 29 example; 48 years old ~ 63 years old age; Wherein single knee joint person 33 example, two knee joint person 28 example, disease time 5 months to 10 years, average 4.2 years.Two groups of not statistically significants (P < 0.05) in sex, age, Morbidity constitution ratio, have comparability.

Diagnostic criteria is according to the methods for clinical diagnosis of modern medicine about gonarthritis:

1. repeatedly strain or trauma history.

2. the gonalgia and send out stiff, morning, WA was comparatively obvious, alleviated after activity, movable many time increase the weight of again, remission after having a rest.

3. later stage pain lasts, joint motion is obviously limited, atrophy of quadriceps femoris, hydrarthrosis, even occurs deformity and articular mobile corpus.

4. can lay one's hand on and friction sound during knee joint flexion-extension motion.

5. knee joint just, position, side photo, display patella, condyle of femur, tibial plateau joint margins be lip sample hyperosteogeny, and intercondylar process of tibia comes to a point, and joint space narrows, the densification of subchondral bone matter, episome in visible joint sometimes.

Therapeutic Method treatment group adopts Chinese medicine composition of the present invention, namely take,: Radix Ixorae Chinensis 45g, Radix Seu Folium Triumfettae Pilosae 6g, Radix Clematidis Henryi 5g, Radix Kadsurae Coccineae 22g, Herba Scleriae Terrestris 24g, Herba Blumeae Laciniatae 25g, Cortex schefflerae octophyllae 12g, Radix Inulae Nervosae 10g, Herba Clematidis Lasiandrae 23g, Rhizoma seu Herba Elatostematis stewardii 18g, Indigofera mentzeana Craib 7g, Radix Campylotropis Macrocarpae 9g, grinding Mel is modulated into ointment, before sleeping every night by external application of ointment in knee joint place; The oral glucosamine of matched group and nonsteroidal analgesia anti-inflammation medicine; Be a course for the treatment of with three months, all treat a course for the treatment of for two groups and add up curative effect.

Criterion of therapeutical effect judges curative effect with reference to " disease of tcm Standardization of diagnosis and curative effect ".Cure: symptom disappears substantially, and joint motion is unrestricted, can normally work; Take a turn for the better: symptom obviously alleviates, and function is normal, can participate in general activity; Invalid: before and after treatment, symptom is not improved.

Therapeutic outcome two groups of therapeutic outcomes see the following form.

By upper table, visible treatment group always has rate to reach 95.0%, and matched group total effective rate reaches 86.8%, and treatment group is obviously better than matched group, and two groups of cure rates, total effective rates have significant difference (P < 0.05).

Detailed description of the invention

Embodiment one: take Radix Ixorae Chinensis 45g, Radix Seu Folium Triumfettae Pilosae 6g, Radix Clematidis Henryi 5g, Radix Kadsurae Coccineae 22g, Herba Scleriae Terrestris 24g, Herba Blumeae Laciniatae 25g, Cortex schefflerae octophyllae 12g, Radix Inulae Nervosae 10g, Herba Clematidis Lasiandrae 23g, Rhizoma seu Herba Elatostematis stewardii 18g, Indigofera mentzeana Craib 7g, Radix Campylotropis Macrocarpae 9g, it is for subsequent use that grinding Mel is modulated into ointment.

Embodiment two: take Radix Ixorae Chinensis 30g, Radix Seu Folium Triumfettae Pilosae 9g, Radix Clematidis Henryi 3g, Radix Kadsurae Coccineae 30g, Herba Scleriae Terrestris 18g, Herba Blumeae Laciniatae 35g, Cortex schefflerae octophyllae 9g, Radix Inulae Nervosae 15g, Herba Clematidis Lasiandrae 9g, Rhizoma seu Herba Elatostematis stewardii 25g, Indigofera mentzeana Craib 6g, Radix Campylotropis Macrocarpae 12g, it is for subsequent use that grinding Mel is modulated into ointment.

Embodiment three: take Radix Ixorae Chinensis 60g, Radix Seu Folium Triumfettae Pilosae 3g, Radix Clematidis Henryi 6g, Radix Kadsurae Coccineae 15g, Herba Scleriae Terrestris 30g, Herba Blumeae Laciniatae 15g, Cortex schefflerae octophyllae 15g, Radix Inulae Nervosae 6g, Herba Clematidis Lasiandrae 18g, Rhizoma seu Herba Elatostematis stewardii 10g, Indigofera mentzeana Craib 9g, Radix Campylotropis Macrocarpae 6g, it is for subsequent use that grinding Mel is modulated into ointment.

Claims

1. treat an external traditional Chinese medicinal application for knee joint osseous arthritis, it is characterized in that this external traditional Chinese medicinal application is made up of the Chinese medicine of following weight portion: Radix Ixorae Chinensis 30-60 part, Radix Seu Folium Triumfettae Pilosae 3-9 part, Radix Clematidis Henryi 3-6 part, Radix Kadsurae Coccineae 15-30 part, Herba Scleriae Terrestris 18-30 part, Herba Blumeae Laciniatae 15-35 part, Cortex schefflerae octophyllae 9-15 part, Radix Inulae Nervosae 6-15 part, Herba Clematidis Lasiandrae 9-18 part, Rhizoma seu Herba Elatostematis stewardii 10-25 part, Indigofera mentzeana Craib 6-9 part, Radix Campylotropis Macrocarpae 6-12 part.

2. a kind of external traditional Chinese medicinal application for the treatment of knee joint osseous arthritis as claimed in claim 1, it is characterized in that this external traditional Chinese medicinal application is made up of the Chinese medicine of following weight portion: preferred, Radix Ixorae Chinensis 45 parts, Radix Seu Folium Triumfettae Pilosae 6 parts, Radix Clematidis Henryi 5 parts, Radix Kadsurae Coccineae 22 parts, Herba Scleriae Terrestris 24 parts, the Herba Blumeae Laciniatae 25 parts, Cortex schefflerae octophyllae 12 parts, Radix Inulae Nervosae 10 parts, Herba Clematidis Lasiandrae 23 parts, Rhizoma seu Herba Elatostematis stewardii 18 parts, Indigofera mentzeana Craib 7 parts, Radix Campylotropis Macrocarpae 9 parts.