CN104998180A - Medicinal preparation for treating constipation - Google Patents
Medicinal preparation for treating constipation Download PDFInfo
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- CN104998180A CN104998180A CN201510458469.4A CN201510458469A CN104998180A CN 104998180 A CN104998180 A CN 104998180A CN 201510458469 A CN201510458469 A CN 201510458469A CN 104998180 A CN104998180 A CN 104998180A
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Abstract
The invention belongs to the filed of traditional Chinese medicine preparations and particularly discloses a medicinal preparation for treating constipation. The medicinal preparation is prepared with, by weight, 18 parts of acorus gramineus soland, 15 parts of kalanchoe pinnata, 20 parts of fructus amomi, 30 parts of dragon bones, 15 parts of semen cassiae, 15 parts of barbary wolfberry fruits, 20 parts of golden cypress, 30 parts of astragalus membranaceus, 20 parts of cistanche, 10 parts of semen armeniacae amarae, 30 parts of oysters, 15 parts of radix achyranthis bidentatae, 15 parts of rhizoma atractylodis macrocephalae and 10 parts of liquorice through extraction. The effect for treating constipation is remarkable.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation, particularly relate to a kind of pharmaceutical preparation for the treatment of constipation.
Background technology
Constipation is a kind of commonly encountered diseases, defecates dry and hard for a long time, within many days, defecates once, and each solution just difficulty is painful, and of a specified duration easily causes Other diseases.The product effect of current treatment constipation is all not so good, is therefore badly in need of a kind of Chinese medicine for the treatment of constipation.
Summary of the invention
Goal of the invention: the object of the present invention is to provide a kind of pharmaceutical preparation for the treatment of constipation.
Technical scheme: a kind of pharmaceutical preparation for the treatment of constipation, it is characterized in that, be prepared from by the Chinese medicine extraction of following weight portion: perfume 18 parts, Herba Bryophylli Pinnati 15 parts, Fructus Amomi 20 parts, Os Draconis 30 parts, Semen Cassiae 15 parts, Fructus Lycii 15 parts, Cortex Phellodendri 20 parts, the Radix Astragali 30 parts, Herba Cistanches 20 parts, Semen Armeniacae Amarum 10 parts, Concha Ostreae 30 parts, Radix Achyranthis Bidentatae 15 parts, the Rhizoma Atractylodis Macrocephalae 15 parts, 10 parts, Radix Glycyrrhizae conveniently.
The pharmaceutical preparation of described treatment constipation, preparation method is: above Chinese medicine, decocts with water 2 times, adds the soak by water 2 hours of medical material weight 10 times amount at every turn, collecting decoction, when being concentrated into 65 DEG C, relative density is 1.2, obtains extractum, spraying dry, pulverize, cross 100 mesh sieves, add adjuvant, make pharmaceutical preparation.
The application of pharmaceutical preparation in preparation treatment constipation medicine of described treatment constipation.
Fragrant conveniently in the present invention is Acorus of Araceae plant fragrant Acorus gramineus Soland.var.pusillus Engl. conveniently, and f.suaveolens C.Y.Cheng, mss., with all herbal medicine.The four seasons can adopt, and dry.Promoting the circulation of QI to relieve pain, dispel the wind by cold, removing toxic substances diuretic, eliminates phlegm for resuscitation.For mental confusion due to phlegm, coma, gnathospasma, stomachache uncomfortable in chest, turbid damp obstructing in middle-JIAO, rheumatic arthritis, colic, edema; Innominate toxic swelling is controlled in external.Herba Bryophylli Pinnati is Crassulaceae Herba Bryophylli Pinnati platymiscium Herba Bryophylli Pinnati Kalanchoe pinnatum (L.) Pers., with all herbal medicine.The whole year can adopt, many using fresh herbs.Removing toxic substances and promoting subsidence of swelling, promoting blood circulation and stopping pain, removing toxic substances and promoting tissue regeneration.Carbuncle pyogenic infections from tumour or sore is controlled in external, mastitis, erysipelas, panaris, traumatic hemorrhage, traumatic injury, fracture, burn and scald, otitis media.All the other are pharmacopeia kind.
Beneficial effect: the traditional Chinese medical science is thought that constipation is many and caused by accumulated heat in gastrointestinal tract, depression and stagnation of QI, right successive dynasties medical science is all thought and can not be abused the method for capturing, apprentice's impairment of body fluid liquid, in the present invention, fragrant, Herba Bryophylli Pinnati heat-clearing and toxic substances removing is monarch drug conveniently, Fructus Amomi, Os Draconis, Semen Cassiae, Fructus Lycii, Cortex Phellodendri, the Radix Astragali, Herba Cistanches, Semen Armeniacae Amarum, Concha Ostreae, Radix Achyranthis Bidentatae, Rhizoma Atractylodis Macrocephalae dispelling cold by warming the meridian, and QI invigorating is ministerial drug, Radix Glycyrrhizae is adjuvant, full side's heat-clearing and toxic substances removing, boosting are defecated, treatment constipation, respond well.
Detailed description of the invention
Embodiment 1: get fragrant 18g, Herba Bryophylli Pinnati 15g, Fructus Amomi 20g, Os Draconis 30g, Semen Cassiae 15g, Fructus Lycii 15g, Cortex Phellodendri 20g, Radix Astragali 30g, Herba Cistanches 20g, Semen Armeniacae Amarum 10g, Concha Ostreae 30g, Radix Achyranthis Bidentatae 15g, Rhizoma Atractylodis Macrocephalae 15g, Radix Glycyrrhizae 10g conveniently, above Chinese medicine, decocts with water 2 times, add the soak by water 2 hours of medical material weight 10 times amount at every turn, collecting decoction, when being concentrated into 65 DEG C, relative density is 1.2, obtains extractum, spraying dry, pulverize, cross 100 mesh sieves, add starch 50g, tabletting, makes tablet.
Embodiment 2: get fragrant 18g, Herba Bryophylli Pinnati 15g, Fructus Amomi 20g, Os Draconis 30g, Semen Cassiae 15g, Fructus Lycii 15g, Cortex Phellodendri 20g, Radix Astragali 30g, Herba Cistanches 20g, Semen Armeniacae Amarum 10g, Concha Ostreae 30g, Radix Achyranthis Bidentatae 15g, Rhizoma Atractylodis Macrocephalae 15g, Radix Glycyrrhizae 10g conveniently, above Chinese medicine, decoct with water 2 times, add the soak by water 2 hours of medical material weight 10 times amount at every turn, collecting decoction, when being concentrated into 65 DEG C, relative density is 1.2, obtain extractum, spraying dry, pulverize, cross 100 mesh sieves, add starch 50g, encapsulating capsule, makes capsule.
Embodiment 3: get fragrant 18g, Herba Bryophylli Pinnati 15g, Fructus Amomi 20g, Os Draconis 30g, Semen Cassiae 15g, Fructus Lycii 15g, Cortex Phellodendri 20g, Radix Astragali 30g, Herba Cistanches 20g, Semen Armeniacae Amarum 10g, Concha Ostreae 30g, Radix Achyranthis Bidentatae 15g, Rhizoma Atractylodis Macrocephalae 15g, Radix Glycyrrhizae 10g conveniently, above Chinese medicine, decocts with water 2 times, adds the soak by water 2 hours of medical material weight 10 times amount at every turn, collecting decoction, when being concentrated into 65 DEG C, relative density is 1.2, obtains extractum, spraying dry, pulverize, cross 100 mesh sieves, add dextrin 50g, make granule.
Embodiment 4: the present invention is on the impact of mice with constipation Small intestine advance activity
Animal, medicine, reagent: animal: healthy ICR mice, male and female half and half, heavy 18-22g, is provided by Shanghai Slac Experimental Animal Co., Ltd., production licence number SCXK (Shanghai) 2013-0003.Pharmaceutical preparation granule of the present invention is prepared by above-described embodiment 3; R-1132, Wujin pharmaceutical factory, 20140823.Phenolphthalein tablets (phenolphthalein sugar-tablet), Junan, Shandong Province pharmaceutical factory, specification: 100mg*100 sheet/box, lot number 20140625
Experimentation: get ICR mice 60, with the modeling of R-1132 50m/kg gavage, continuous 10 days, period normal diet, form Constipation Model, random packet, often organize about 10, male and female half and half, be divided into normal group, model group, positive drug group (giving phenolphthalein tablets), pharmaceutical preparation of the present invention is high, in, low three dosage groups, administration is the same, successive administration 14d, before experiment, water 12h is can't help in fasting, 2h after last administration, gavage with the charcoal end arabic gum suspension lml/g that volume fraction is 5% respectively, each group of mice is put to death after 20min, cut open the belly and measure every Mus small intestinal charcoal end displacement and total small intestinal length, be converted into the percentage rate that charcoal end displacement accounts for total small intestinal length, t test and judge group difference, the results are shown in Table 1.
Table 1 the present invention is on the impact (n=10) of mice with constipation Small intestine advance activity
Compare with model group, * * P<0.01*P<0.05, compares with positive drug group, ##P<0.01#P<0.05
Result: pharmaceutical preparation of the present invention is compared with model group, have and obviously promote mice with constipation Small intestine advance activity, promote gastrointestinal motility in mice, there is significant difference, compare with positive drug, pharmaceutical preparation senior middle school of the present invention dosage group has significant difference in promotion mice with constipation Small intestine advance activity, and effect is better than positive drug, illustrates that it has the effect for the treatment of constipation.
Claims (3)
1. treat the pharmaceutical preparation of constipation for one kind, it is characterized in that, be prepared from by the Chinese medicine extraction of following weight portion: perfume 18 parts, Herba Bryophylli Pinnati 15 parts, Fructus Amomi 20 parts, Os Draconis 30 parts, Semen Cassiae 15 parts, Fructus Lycii 15 parts, Cortex Phellodendri 20 parts, the Radix Astragali 30 parts, Herba Cistanches 20 parts, Semen Armeniacae Amarum 10 parts, Concha Ostreae 30 parts, Radix Achyranthis Bidentatae 15 parts, the Rhizoma Atractylodis Macrocephalae 15 parts, 10 parts, Radix Glycyrrhizae conveniently.
2. treat the pharmaceutical preparation of constipation as claimed in claim 1, it is characterized in that, preparation method is: above Chinese medicine, decoct with water 2 times, add the soak by water 2 hours of medical material weight 10 times amount, collecting decoction, when being concentrated into 65 DEG C, relative density is 1.2 at every turn, obtain extractum, spraying dry, pulverizes, and crosses 100 mesh sieves, add adjuvant, be prepared into pharmaceutical preparation.
3. treat the application of pharmaceutical preparation in treatment constipation medicine of constipation as claimed in claim 1.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510458469.4A CN104998180A (en) | 2015-07-30 | 2015-07-30 | Medicinal preparation for treating constipation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510458469.4A CN104998180A (en) | 2015-07-30 | 2015-07-30 | Medicinal preparation for treating constipation |
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| Publication Number | Publication Date |
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| CN104998180A true CN104998180A (en) | 2015-10-28 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201510458469.4A Pending CN104998180A (en) | 2015-07-30 | 2015-07-30 | Medicinal preparation for treating constipation |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101129771A (en) * | 2007-08-27 | 2008-02-27 | 尹克华 | Traditional Chinese medicine for treating bradykinesia type constipation |
| KR20110048431A (en) * | 2009-11-02 | 2011-05-11 | 박의신 | Functional product that treats and prevents obesity, constipation and fatty liver |
-
2015
- 2015-07-30 CN CN201510458469.4A patent/CN104998180A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101129771A (en) * | 2007-08-27 | 2008-02-27 | 尹克华 | Traditional Chinese medicine for treating bradykinesia type constipation |
| KR20110048431A (en) * | 2009-11-02 | 2011-05-11 | 박의신 | Functional product that treats and prevents obesity, constipation and fatty liver |
Non-Patent Citations (2)
| Title |
|---|
| 王洪斌等: "中医药治疗老年功能性便秘40例", 《现代医药卫生》 * |
| 金萍: "加味黄芪汤治疗老年气虚型便秘临床观察", 《中国老年保健医学》 * |
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| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20151028 |
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| WD01 | Invention patent application deemed withdrawn after publication |