CN104922258A - Strangles powder and application thereof to preparation of drugs for preventing and treating strangles and abscess - Google Patents

Strangles powder and application thereof to preparation of drugs for preventing and treating strangles and abscess Download PDF

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CN104922258A
CN104922258A CN201510293161.9A CN201510293161A CN104922258A CN 104922258 A CN104922258 A CN 104922258A CN 201510293161 A CN201510293161 A CN 201510293161A CN 104922258 A CN104922258 A CN 104922258A
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parts
powder
strangles
adenitis equorum
equorum
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CN104922258B (en
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况玲
姚刚
王金泉
郭庆勇
苏战强
赵红琼
包拉提·吾木尔别克
李海
买占海
刘媛媛
周银萍
卢亚宾
张彩云
张桃
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Xinjiang Agricultural University
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Xinjiang Agricultural University
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    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
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    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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Abstract

The invention discloses strangles powder and application thereof to preparation of drugs for preventing and treating strangles and abscess. According to the invention, 5-8 parts of codonopsis pilosula, 5-9 parts of wine-washed angelica sinensis, 5-9 parts of fried paeonia lactiflora, 10 parts of pericarpium citri reticulatae, 15 parts of honeysuckle, 3 parts of angelica dahurica, 10 parts of wild chrysanthemum, 5 parts of fried astragalus membranaceus, 5 parts of ligusticum wallichii, 5 parts of fried atractylodes macrocephala Koidz, 5 parts of poria cocos, 15 parts of forsythia suspense, 2 parts of Chinese honeylocust spine and 5 parts of raw liquorice are carefully selected and subjected to impurity removal, then the materials are ground into fine powder and screened through a 40-mesh sieve, the screened materials are put into a porcelain pot, water is added to blend the materials to be pasty, decoction is carried out for 10 minutes and stirring is carried out continuously during decoction, or the powder is brewed to be pasty through boiled water, the pasty material is used for feeding through a nasogastric tube after being cooled, and a pony can be fed with the pasty material through a young animal milk bottle. The sick animal is fed with the strangles powder once a day, preferably, the sick animal is fed with the strangles powder in the morning, and one treatment course is 7 days; after the prepared strangles powder is used for treating dozens of sick animals with strangles, malignant strangles and multiple abscess, the using effect is obvious, non-toxicity and no side effects are realized and a higher application value is realized.

Description

A kind of adenitis equorum powder and the application prevented and treated in adenitis equorum and abscess medicine in preparation
Technical field
The invention belongs to veterinary medicine technical field, specifically, the present invention relates to Chinese herbal medicine is the technical field of horse oral drugs prepared by raw material, further specifically, the present invention relates to a kind of adenitis equorum powder and prevents and treats in preparation the technical field applied in adenitis equorum and abscess medicine.
Background technology
Chinese medicine takes stopgap measures and effects a permanent cure, and low toxicity noresidue, has no side effect, and rather accepts in the various disease of control animal and selects, being widely used in the various diseases of control poultry, respond well.
Adenitis equorum and abscess belong to horse-sickness colt below 2 years old, especially encroach on half years old to one-year-old coltfoal multiple, be a kind of Acute exposure sexually transmitted disease of horse, mule, donkey, have generation all over the world, show as three types clinically, one crosses type, typical case, pernicious adenitis equorum.Because long-term abuse of antibiotics prevents and treats, so that antibiotic therapy effect is poor, there is abscess in especially pernicious adenitis equorum colt whole body and internal organs many places, antibiotic therapy effect extreme difference, almost mortality rate reaches more than 90%, even if curing also is that the treatment phase is very long, the growth promoter of colt is obstructed, what prevent and treat adenitis equorum is the vital task that veterinary clinic and modern horse industry develop, and is all adenitis equorum time of origin, has a strong impact on the growth promoter of colt in annual autumn and the Spring Festival.Domestic shortage adenitis equorum vaccine, even if the protective rate of adenitis equorum vaccine does not reach 70% yet abroad, especially Chinese cause of disease and external pathogen variant, protective rate is just lower, and some mature horses made, after import, adenitis equorum occur.Basis generally uses antibiotic therapy, and the bacterial antibiotic being produces drug resistance, to such an extent as to dosage is continuing to increase clinically, and the toxic and side effects being strengthens, and has a strong impact on the growth of colt.Chinese medicine has the advantage of Mutiple Targets, wide usefulness, low toxicity pair, is widely used in clinical prevention various diseases.
Treatment by Chinese herbs adenitis equorum and multiple abscess are one of traditional therapies, and Chinese veterinarian thinks that adenitis equorum and multiple abscess belong to skin ulcer general edema with yellowish skin poison more.Chinese veterinarian thinks that the principal pathogenetic reason of the yellow furunculosis of skin ulcer is diseases caused by exogenous pathogenic factor six evils, just has that " among meridians, then blood tears, blood tears are then obstructed, and general rule is not defended gas and returned it, must not answer instead, therefore carbuncle also for cold-evil visitor as far back as "Nei Jing".Cold turns to heat, and domination of heat is slough then, rottenness of muscle forming pus." and the full forced labour of internal injury famine, " unit is prosperous treats Ma Ji " is thought " skin ulcer person, gas decline also, weakness of QI and blood is puckery, blood is puckery and invade meat reason, and meat reason is stayed for a long period and meat is rotten, meat corruption person, is turn to pus ".Adenitis equorum is mainly mainly in autumn and winter, and occasionally there is generation in spring, and how rapid the change of this seasonal weather is, and colt especially then is just weaned, and resistance is poor, multiple.Visible, current how better according to Chinese medicine principle, design and a kind ofly prevent and treat the low toxicity noresidue of adenitis equorum and abscess in preparation, the medicine effected a permanent cure that takes stopgap measures of having no side effect has realistic meaning and highlight its effect.
When proof horse generation adenitis equorum and multiple abscess, human body immune function weakens according to the study, colt growth promoter is impaired, also report Chinese herbal treatment is had clinically, but owing to lacking pathogenic factor and study of pathogenesis, medication is various clinically, and effect is not very consistent, verification effective, do not verify, effect does not show, and lacks for adenitis equorum and the multiple abscess effective Chinese medicine formula from basic control.
Summary of the invention
For the present situation for the treatment of horse adenitis equorum and multiple abscess medicine at present both at home and abroad, object of the present invention is intended to provide a kind of adenitis equorum powder and preparing the application prevented and treated in adenitis equorum and abscess medicine, extremely effective treating both the principal and secondary aspects of a disease, curative effect are fast, the Chinese medicine formula preventing and treating adenitis equorum and multiple abscess of good effect, efficacy stability to provide one to have, use low toxicity, noresidue, have no side effect, and the convenient treatment adenitis equorum of enforcement and the Chinese herbal medicine oral medicine of multiple abscess, possess preparation simple simultaneously, be easy to the features such as operation.
Solution of the present invention is to the pathogenic factor of adenitis equorum and multiple abscess and pathogenetic understanding thereof and control principle based on motherland's traditional Chinese veterinary medicine, theory and the control principle of adenitis equorum and multiple abscess is is effectively prevented and treated according to traditional Chinese veterinary medicine tradition, with reference to modern pharmacological research achievement, from motherland's medicine treasure-house, scorchingly hot card is ruled by law according to heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling ruling by law syndrome of blood stasis, the dialectical principle of " three card three methods " of strengthening the body resistance ruling by law Acute Deficiency Syndrome, the formula that original Chinese veterinarian's medicine prescription basis sums up through clinical practice for many years again, filter out heat-clearing and toxic substances removing, fill blood, blood circulation promoting and blood stasis dispelling, the saturating pus in Tuoli, strengthening the body resistance, the natural Chinese medicinal herb of enhancing body resistance, through clinical repetition test for many years, develop a kind of to adenitis equorum and multiple abscess instant effect, treating both the principal and secondary aspects of a disease, low toxicity, noresidue, the oral drugs had no side effect.Its effect is the pathogen in heat-clearing and toxic substances removing energy purged body, discharges the noxious dampness in body, the normal temperature of body recovery; Blood circulation promoting and blood stasis dispelling can improve body blood circulation, discharges the toxin in body, and congestive edema is dissipated; Fill blood, strengthening the body resistance, the resistance against diseases of body can be improved, enhancing immunity, the capable then blood of gas, accelerate the ulceration of congestive edema; During the saturating pus in Tuoli, expelling pathogens by strengthening vital qi and expelling pus, Tuoli are clear, exactly poison are discharged from inside to outside, accelerate the discharge of pus, the cleaning open sore part, healing acceleration.Extremely remarkable in the result of use in recent years through the sick horse of tens of example.
Particularly, the invention provides a kind of for the preparation of preventing and treating the adenitis equorum powder applied in adenitis equorum and abscess medicine, adenitis equorum powder component is assessed by weight, Radix Codonopsis 5 parts-8 parts, Radix Angelicae Sinensis 5 parts-9 parts, Radix Paeoniae 5 parts-9 parts, Pericarpium Citri Reticulatae 10 parts-15 parts, Flos Lonicerae 15 parts-20 parts, the Radix Angelicae Dahuricae 3 parts-6 parts, Flos Chrysanthemi Indici 10 parts-15 parts, the Radix Astragali 5 parts-10 parts, Rhizoma Chuanxiong 5 parts-8 parts, the Rhizoma Atractylodis Macrocephalae 5 parts-8 parts, 5 parts-8 parts, Poria, Fructus Forsythiae 15 parts-20 parts, Spina Gleditsiae 2 parts-5 parts, Radix Glycyrrhizae 5 parts-8 parts.
In the formula of above-mentioned adenitis equorum powder provided by the invention, the Chinese crude drug selected can be bought by market and obtain, select Radix Angelicae Sinensis(soaked with wine), parch Radix Paeoniae, the parch Radix Astragali, the parch Rhizoma Atractylodis Macrocephalae to be all the method that important normal method selects raw material of Chinese medicine to prepare, existing middle means can be looked into everywhere during raw material of Chinese medicine is concocted and adopt wine to wash and stir-frying-technology.
Simultaneously, the invention provides the using method of the adenitis equorum powder for preventing and treating adenitis equorum and abscess: choose with Radix Codonopsis, Radix Angelicae Sinensis (wine is washed), Radix Paeoniae (stir-fry), Pericarpium Citri Reticulatae, Flos Lonicerae, the Radix Angelicae Dahuricae, Flos Chrysanthemi Indici, the Radix Astragali (stir-fry), Rhizoma Chuanxiong, the Rhizoma Atractylodis Macrocephalae (stir-fry), Poria, Fructus Forsythiae, Spina Gleditsiae, Radix Glycyrrhizae as determining raw material, through weighing, pulverizing, add boiled water furnishing scattered paste shape, emergency case stomach catheter gavages, or spice is fed.Through the checking of long-term sick horse disease example, provided by the invention for the preparation of preventing and treating the adenitis equorum powder Be very effective applied in adenitis equorum and abscess medicine, nontoxic, have no side effect.
The Chen Shigong recorded according to prior art " carbuncle, brain item furunculosis large carbuncle(disease); though situation is for outward; and by disease source really in also ", " all carbuncle persons; do not have the not first invading five ZANG-organs then to send out it ", " the five internal organs then six internal organs of getting along well are obstructed, and six internal organs are the tired gallery of general rule nine orifices not, and the tired gallery of nine orifices is then stayed and become carbuncle ".Adenitis equorum powder provided by the invention utilizes Chinese medicine Radix Codonopsis, Radix Angelicae Sinensis (wine is washed), Radix Paeoniae (stir-fry), Pericarpium Citri Reticulatae, Flos Lonicerae, the Radix Angelicae Dahuricae, Flos Chrysanthemi Indici, the Radix Astragali (stir-fry), Rhizoma Chuanxiong, the Rhizoma Atractylodis Macrocephalae (stir-fry), Poria, Fructus Forsythiae, Spina Gleditsiae, Radix Glycyrrhizae is Chinese herbal medicine, boiled water decoction or boiled water punching is adopted to scald, cool, stomach catheter imports and gavages, therefore the adenitis equorum powder of preparation is exactly, and according to theory of Chinese medical science, " lid Tuoli then QI and blood is strengthened and taste Sheng, make pus dirty from row, poison is explained by oneself, carrion is from bursting, new meat is spontaneous, diet is from entering, the open sore part is from holding back " formulate, there is heat-clearing and toxic substances removing, fill blood, blood circulation promoting and blood stasis dispelling, the characteristic of the saturating pus in Tuoli, for prevention and therapy adenitis equorum and multiple abscess.Through clinical repetition test for many years, the present invention develops and provides a kind of to adenitis equorum and multiple abscess instant effect, treating both the principal and secondary aspects of a disease, low toxicity, noresidue, the oral drugs that have no side effect, i.e. adenitis equorum powder provided by the invention, its effect is the pathogen in heat-clearing and toxic substances removing energy purged body, discharges the noxious dampness in body, the normal temperature of body recovery; Blood circulation promoting and blood stasis dispelling can improve body blood circulation, discharges the toxin in body, and congestive edema is dissipated; Fill blood, strengthening the body resistance, the resistance against diseases of body can be improved, enhancing immunity, the capable then blood of gas, accelerate the ulceration of congestive edema; During the saturating pus in Tuoli, expelling pathogens by strengthening vital qi and expelling pus, Tuoli are clear, exactly poison are discharged from inside to outside, accelerate the discharge of pus, the cleaning open sore part, healing acceleration.Extremely remarkable in the result of use in recent years through the sick horse of tens of example.
Based on Chinese medicine traditional theory, mostly adenitis equorum and multiple abscess are, because feeding and management is improper, to be affected by the cold, infect streptococcus equi, cause and infect, clinical manifestation body temperature rises to 39-40 DEG C, and breathing, pulse increase number, palpitating speed, spirit is depressed, and appetite declines, and catarrhal inflammation appears in bronchia mucosal, nasal secretion increases, and the development with the state of an illness shows as serosity, purulence change; During concurrent pharyngolaryngitis, pressing pharyngeally has pain, breathes acataposis; Submandibular lymph nodes swelling is as fist size, and their early stage abscess is hard, and later stage abscess position is softened, and has fluctuation, flows yellow-white curdy pus after ulceration.The present invention is intended to utilize natural Chinese medicinal herb, and the adenitis equorum powder of preparation provides effective remedy measures for adenitis equorum and multiple abscess, has no side effect, obtain heat-clearing and toxic substances removing, spleen invigorating fill blood, the saturating pus in Tuoli, enhancing body resistance, without recurrence, the low oral medicine with facilitating administration of cost.
In adenitis equorum powder component provided by the invention, Flos Lonicerae, Flos Chrysanthemi Indici, Fructus Forsythiae, heat-clearing and toxic substances removing, induces sweat, and dispelling pathogen in the interior expels the heat-evil; Radix Codonopsis, the Radix Astragali (stir-fry), the Rhizoma Atractylodis Macrocephalae (stir-fry), Radix Paeoniae (stir-fry), Poria, air making-up and spleen enlivening, ascending up spleen-Qi and Yang, astringing to arrest diarrhea; Radix Angelicae Sinensis (wine is washed), Rhizoma Chuanxiong, Pericarpium Citri Reticulatae, blood circulation promoting and blood stasis dispelling, promoting the circulation of QI to relieve pain; The Radix Angelicae Dahuricae, Spina Gleditsiae, the saturating pus in Radix Glycyrrhizae Tuoli, reducing swelling and alleviating pain; Compatibility uses energy heat-clearing and toxic substances removing, detumescence, the saturating pus in Tuoli, air making-up and spleen enlivening, coordinating the actions of various ingredients in a prescription, enhancing body resistivity.Can be used for preventing and treating adenitis equorum and multiple abscess.
Adenitis equorum powder provided by the invention powder composition preparation in treatment adenitis equorum and multiple abscess is simple, pure Chinese medicinal components, composition is fastidious, scientific and reasonable, have no side effect, easy to use, a general course for the treatment of can fully recover, and pernicious adenitis equorum and multiple abscess use the 2-3 course for the treatment of, curative effect is fast, good effect, efficacy stability, especially can prevent pernicious adenitis equorum and multiple recurrence.
By implementing the concrete summary of the invention of the present invention, following effect can be reached:
(1) the present invention selects pure natural Chinese medicinal herb to be raw material, meets pharmaceutical control law regulation.Each taste Chinese herbal medicine compatibility effect is utilized to treat adenitis equorum and multiple abscess.The adenitis equorum powder of preparation has heat-clearing and toxic substances removing, air making-up and spleen enlivening, blood circulation promoting and blood stasis dispelling, the saturating pus in Tuoli, convergence granulation promoting, and enhancing body digestion power, improves immunity of organisms, and promote abscess ulceration, erosion prevention and muscle growing, gets well.This medicine low toxicity noresidue, does not have detrimental effect to body internal organs organ.Apply adenitis equorum powder provided by the invention and treat 76 routine adenitis equorum altogether in 2 years, wherein colt 75 example, mature horses 1.Within 3-7 days, just promote that abscess is discharged, relief of symptoms, 7 days is a course for the treatment of, then effectively can cures, make colt well-grown with three courses for the treatment of.
(2) the powder heat-clearing and toxic substances removing of adenitis equorum powder treatment adenitis equorum provided by the invention and multiple abscess, air making-up and spleen enlivening, blood circulation promoting and blood stasis dispelling, the saturating pus in Tuoli, convergence granulation promoting, enhancing body digestion power, improve immunity of organisms, adjust a series of diseases because local or systemic inflammatorome cause.Through the routine applicable cases of clinical treatment 76, one crosses type ill domestic animal 35 example, and 7-14 days cure rates are recovery from illness in about 77.1%, 28 days is 22.9%; Typicality 27 example, 7-14 days cure rates are recovery from illness in about 44.4%, 28 days is 55.6%; Pernicious 14 examples, 7-14 days cure rates are recovery from illness in about 7.1%, 28 days is 57.1%, secondary pyaemia septica 4-case death.
Detailed description of the invention
, for embodiment, the present invention is described below, but the present invention is not limited to following embodiment.
In in the formula medical material of adenitis equorum powder provided by the invention with Radix Codonopsis, Radix Angelicae Sinensis, Radix Paeoniae, Pericarpium Citri Reticulatae, Flos Lonicerae, the Radix Angelicae Dahuricae, Flos Chrysanthemi Indici, the Radix Astragali, Rhizoma Chuanxiong, the Rhizoma Atractylodis Macrocephalae, Poria, Fructus Forsythiae, Spina Gleditsiae, Radix Glycyrrhizae for determining raw material, wherein, select Radix Angelicae Sinensis(soaked with wine), parch Radix Paeoniae, the parch Radix Astragali, the parch Rhizoma Atractylodis Macrocephalae to be all the method that important normal method selects raw material of Chinese medicine to prepare, existing middle means can be looked into everywhere during raw material of Chinese medicine is concocted and adopt Radix Angelicae Sinensis (wine is washed), Radix Paeoniae (stir-fry), the Radix Astragali (stir-fry) and the Rhizoma Atractylodis Macrocephalae (stir-fry) technique.
The supplementary materials such as all Chinese herbal medicine selected in the present invention are all well known selecting, but do not limit enforcement of the present invention, in addition, in following explanation, if no special instructions, the adenitis equorum powder component that the present invention adopts, all adopt weight part ratio to assess in proportioning, this part is also the common mode of the field of Chinese medicines than compatibility.
Embodiment one: for preventing and treating the preparation of the adenitis equorum powder of adenitis equorum and multiple abscess
The present invention specifically provides a kind of adenitis equorum powder preventing and treating adenitis equorum and multiple abscess, is obtained by the preparation method provided as follows:
Principal agent raw material Radix Codonopsis 5 parts-8 parts, Radix Angelicae Sinensis 5 parts-9 parts, Radix Paeoniae 5 parts-9 parts, Pericarpium Citri Reticulatae 10 parts-15 parts, Flos Lonicerae 15 parts-20 parts, the Radix Angelicae Dahuricae 3 parts-6 parts, Flos Chrysanthemi Indici 10 parts-15 parts, the Radix Astragali 5 parts-10 parts, Rhizoma Chuanxiong 5 parts-8 parts, the Rhizoma Atractylodis Macrocephalae 5 parts-8 parts, 5 parts-8 parts, Poria, Fructus Forsythiae 15 parts-20 parts, Spina Gleditsiae 2 parts-5 parts, Radix Glycyrrhizae 5 parts-8 parts in adopting, selected roguing thing, grinding fine powder crosses 40 orders.
Further, the invention provides the using method of the adenitis equorum powder for preventing and treating adenitis equorum and multiple abscess:
Specifically each for adenitis equorum powder raw material was put into porcelain pot through pulverizing 40 orders, add water and play the part of scattered paste shape, decoct 10 minutes, period does not stop to stir, and also boiled water punching can scald into scattered paste shape, cool nasogastric tube and throw clothes, pony can use the administration of young stock feeding bottle.1 time on the 1st, every morning is best, within 7 days, is a course for the treatment of; Use middle successful, nontoxic, have no side effect.
Apply the above-mentioned adenitis equorum powder treatment adenitis equorum provided, pernicious adenitis equorum, the tens of example of multiple abscess.
Embodiment two: for preventing and treating the preparation of the adenitis equorum powder of adenitis equorum and multiple abscess
Principal agent raw material Radix Codonopsis 5 parts, Radix Angelicae Sinensis (wine is washed) 5 parts, Radix Paeoniae (stir-fry) 5 parts, Pericarpium Citri Reticulatae 10 parts, Flos Lonicerae 15 parts, the Radix Angelicae Dahuricae 3 parts, Flos Chrysanthemi Indici 10 parts, the Radix Astragali (stir-fry) 5 parts, Rhizoma Chuanxiong 5 parts, the Rhizoma Atractylodis Macrocephalae (stir-fry) 5 parts, 5 parts, Poria, Fructus Forsythiae 15 parts, Spina Gleditsiae 2 parts, Radix Glycyrrhizae 5 parts in adopting, selected roguing thing, porcelain pot is put into after grinding fine powder crosses 40 orders, add water and play the part of scattered paste shape, decoct 10 minutes, period does not stop to stir, also boiled water punching scattered paste shape can be scalded into, cool nasogastric tube and throw clothes, pony can use the administration of young stock feeding bottle.1 time on the 1st, every morning is best, within 7 days, is a course for the treatment of; The adenitis equorum powder treatment adenitis equorum of application preparation, pernicious adenitis equorum, the tens of example of multiple abscess, uses middle successful, nontoxic, have no side effect.
Embodiment three: for preventing and treating the preparation of the adenitis equorum powder of adenitis equorum and multiple abscess
Principal agent raw material Radix Codonopsis 8 parts, Radix Angelicae Sinensis 9 parts, Radix Paeoniae 9 parts, Pericarpium Citri Reticulatae 15 parts, Flos Lonicerae 20 parts, the Radix Angelicae Dahuricae 6 parts, Flos Chrysanthemi Indici 15 parts, the Radix Astragali 10 parts, Rhizoma Chuanxiong 8 parts, the Rhizoma Atractylodis Macrocephalae 8 parts, 8 parts, Poria, Fructus Forsythiae 20 parts, Spina Gleditsiae 5 parts, Radix Glycyrrhizae 8 parts in adopting, selected roguing thing, porcelain pot is put into after grinding fine powder crosses 40 orders, add water and play the part of scattered paste shape, decoct 10 minutes, period does not stop to stir, and boiled water punching can scald into scattered paste shape yet, cool nasogastric tube and throw clothes, pony can use the administration of young stock feeding bottle.1 time on the 1st, every morning is best, within 7 days, is a course for the treatment of; The adenitis equorum powder treatment adenitis equorum of application preparation, pernicious adenitis equorum, the tens of example of multiple abscess, uses middle successful, nontoxic, have no side effect.
Embodiment four: for preventing and treating the preparation of the adenitis equorum powder of adenitis equorum and multiple abscess
Principal agent raw material Radix Codonopsis 7 parts, Radix Angelicae Sinensis (wine is washed) 7 parts, Radix Paeoniae (stir-fry) 6 parts, Pericarpium Citri Reticulatae 12 parts, Flos Lonicerae 18 parts, the Radix Angelicae Dahuricae 5 parts, Flos Chrysanthemi Indici 12 parts, the Radix Astragali (stir-fry) 8 parts, Rhizoma Chuanxiong 7 parts, the Rhizoma Atractylodis Macrocephalae (stir-fry) 6 parts, 6 parts, Poria, Fructus Forsythiae 17 parts, Spina Gleditsiae 3 parts, Radix Glycyrrhizae 6 parts in adopting, selected roguing thing, porcelain pot is put into after grinding fine powder crosses 40 orders, add water and play the part of scattered paste shape, decoct 10 minutes, period does not stop to stir, also boiled water punching scattered paste shape can be scalded into, cool nasogastric tube and throw clothes, pony can use the administration of young stock feeding bottle.1 time on the 1st, every morning is best, within 7 days, is a course for the treatment of; The adenitis equorum powder treatment adenitis equorum of application preparation, pernicious adenitis equorum, the tens of example of multiple abscess, uses middle successful, nontoxic, have no side effect.
Embodiment five: the application in adenitis equorum and multiple abscess prevented and treated by adenitis equorum powder
Certain herdsman one 9 monthly age crossbreeding and improvement mare coltfoal, wean the 10th day, feed with drylot feeding with 8 dry goods coltfoals and 15 adult mares, after weaning the 5th day there is rhinorrhea in 8 dry goods coltfoals successively, the symptoms such as mandibular lymph node enlargement, this horse physique in herds of horses is less, wean more Zao than all the other colt times, grow poor, malnutrition, dry by hair shaft, erect, wean and occur suppurating property nasal mucus on the 6th day, left side mandibular lymph node enlargement, hard as egg size, right side shoulder ALN enlargement in the 8th day of weaning is that goose egg is large firmly, spirit occurs depressed, inappetence, body temperature raises, start western medicine, but there is inguinal lymph nodes successively again, the large leg outer side enlargement of right hind, hard as fist size, poultry main warp Western medicine is controlled.
Embodiment six: the application in adenitis equorum and multiple abscess prevented and treated by adenitis equorum powder
One, certain stud-farm 7 monthly age crossbreeding and improvement horse yearling colt, wean after mare death, feed together with 32 stallion coltfoals of weaning, in 32 dry goods coltfoals, had part colt to infect adenitis equorum streptococcus, this colt infected 4 adenitis equorum streptococcus once, this colt after 7 days of weaning occurs that spirit is depressed, flows yellow purulence nasal mucus, dyspnea, appetite is normal, body temperature raises, and build is partially thin, and body constitution is poor.Find that left side mandibular lymph node enlargement is fist size, swallowing lymph node and poke is ball size and hard, and through Western medicine 1,600,000 IU penicillin 4, sulfadiazine sodium 10mL, intravenous injection, therapeutic effect is not good.
Table 1: the testing result before blood routine treatment
Drawn by table 1, medical record 1 obviously raises with the leukocyte count of medical record 2, shows two sick colt immunologic function degression, has inflammation to occur; In medical record 2, Erythrocytes, hemoglobin, packed cell volume all obviously reduce, and show to answer feeding and management improper after sick colt wean in medical record 2, and become thin, the infection of adenitis equorum etc. cause Anemia.According to clinical symptoms and lab testing, medical record 1 is diagnosed as typical adenitis equorum, and medical record 2 is diagnosed as pernicious adenitis equorum.
Treatment: with heat-clearing and toxic substances removing, dissipating blood stasis for subsidence of swelling, expelling pathogens by strengthening vital qi and expelling pus, tonify deficiency spleen invigorating, throat, be the rule for the treatment of.According to the state of an illness, determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs.Application adenitis equorum loose course for the treatment of, medical record 1 is cured, two the course for the treatment of case 2 to cure, and all without recurring.
Table 2: the testing result after blood routine treatment
Table 3: the change of adenitis equorum disease treatment by Chinese herbs routine blood test
Testing index Before medication After medication
Total white blood cells (10* 9/L) 27.365±6.35 a 10.495±0.287 b
Lymphocyte (10* 9/L) 10.599±3.36322 a 5.577±0.22385 a
Intermediate cell (10* 9/L) 1.6725±0.27471 A 0.6505±0.04013 B
Intermediate cell ratio (%) 7.945±0.66247 a 6.085±0.4254 b
Granulocyte (10* 9/L) 8.356±1.27854 A 4.603±0.26371 B
Erythrocytes (10* 12/L) 7.279±0.53368 A 8.951±0.2733 B
Hemoglobin (g/L) 134.62±6.2885 a 143.015±3.65742 a
Packed cell volume (%) 30.59±2.029 a 36.755±1.05665 b
Hemoglobin concentration (g/L) 267.4±31.71472 a 389.3±4.17266 b
Content of hemoglobin (Pg) 20.6316±2.16924 a 15.995±0.20487 b
Note: in colleague's average subscript, same letter represents difference not significantly (P>0.05), a, b represent significant difference (P<0.05), and A, B represent that difference extremely significantly (P < 0.01).
See table 2, 3, after using Chinese medicine powder for promoting pus discharge treatment adenitis equorum, leukocyte count is down in normal range by higher, significant difference (P<0.05), decline after the medication of intermediate cell ratio significant difference (P<0.05), the difference that declines after intermediate cell medication extremely significantly (P<0.01), difference is reduced extremely significantly (P<0.01) after the medication of granulocyte number, Erythrocytes before medication not within normal range, Normal variations is increased to extremely significantly (P<0.01) after medication, significant difference (P<0.05) is raised after packed cell volume and hemoglobin concentration medication, decline after content of hemoglobin medication significant difference (P<0.05).Illustrate that using powder for promoting pus discharge that abscess ulceration can be made rapidly to reduce inflammation recovers the effect of body constitution.
Table 4: physiological acoustic signals in treatment by Chinese herbs antigourmeaux sera
Before medication (n=23) After medication (n=23)
Blood glucose (GLU) 0.4945±0.33645 A 3.7674±0.27369 B
Total protein (TP) 32.4902±2.63697 a 31.1934±4.41733 a
Total bilirubin (T-BILI) 15.5884±2.06885 a 22.0768±2.84146 a
Albumin (ALB) 29.2342±2.49179 a 38.0609±1.75113 b
Bilirubin direct (D-BILI) 42.906±10.27733 a 13.3974±8.7269 b
Triglyceride (TG) 0.3597±0.05192 a 0.155±0.4565 b
Glutamyl transferase (GGT) 15.1875±1.30045 a 16.3949±1.06703 a
Glutamic oxaloacetic transaminase, GOT (AST) 235.1073±21.60175 a 163.331±31.07577 b
Alanine aminotransferase (ALT) 14.3375±2.13107 a 16.9943±1.42048 a
Alkali phosphatase (ALP) 417.9614±27.86256 a 315.4188±30.01842 b
Note: in colleague's average subscript, a, b, expression significant difference (P<0.05), A, B represent that difference extremely significantly (P < 0.01), and same letter represents that difference is not remarkable.
In table 4, use treatment by Chinese herbs: after curing, blood glucose is significantly elevated in normal range (P<0.001); Bilirubin direct after medication, triglyceride, aspartate amino transferase, alkali phosphatase are significantly reduced to normal range value (P<0.05), cure postalbumin and significantly raise (P<0.05).Illustrate that Chinese medicine has immunity moderation function, and there is liver protective effect.
Table 5: infect adenitis equorum and use Chinese medicine different time TNF-a and IL-6 numerical value
TNF-a IL-6
Before medication 19.216±0.479 A 23.85±2.364 a
With 3 days 9.069±0.479 B 13.135±2.364 b
With 5 days 6.991±0.479 C 6.92±2.364 c
Note: with in column mean subscript, a, b, c represent significant difference (P<0.05), and A, B, C represent that difference extremely significantly (P < 0.01).All have a labelling same letter to be difference remarkable, all there is different Reference character be significant difference.
In table 5, medication 3 days, medication extremely significantly reduce (P<0.01) for 5 days compared with TNF-a level before medication, and medication extremely significantly reduces (P<0.01) with the medication TNF-a level of 5 days for 3 days; IL-6 level before medication 3 days and medication significantly reduces (P<0.05), difference (P>0.05) compared with medication 5, IL-6 level before medication 5 days and medication extremely significantly reduces (P<0.01), illustrates that powder for promoting pus discharge is proinflammatory and it is obvious to recover body inflammatory reaction effect.
Embodiment seven: the application in adenitis equorum and multiple abscess prevented and treated by adenitis equorum powder
The object of observation:
Said medicine is verified case collects 76 complete examples altogether, carry out statistical analysis, satisfactory effect.Wherein one cross type adenitis equorum ill domestic animal 35 example, typicality adenitis equorum 27 example, pernicious adenitis equorum 14 example.The tracing study several months, substantially do not recur.
Therapeutic Method:
The adenitis equorum powder treatment adenitis equorum that application above-described embodiment provides, adopt boiled water punching to scald into scattered paste shape, cool nasogastric tube and throw clothes, pony can use the administration of young stock feeding bottle.1 time on the 1st, every morning is best, within 7 days, is a course for the treatment of.
Clinical results:
1. criterion of therapeutical effect:
Effective: clinical symptom disappearance, through sending out season without recurrence well, and treat without the need to other drug.
Effective: remission, through sending out well attack times minimizing in season, degree alleviates, and application conventional medicine just can control.
Invalid: bad during state of an illness fashion, symptom is without improvement.
2. result:
All clinical datas are carried out finishing analysis and the state of an illness with examining, and according to effective, effectively and null criterion compare, observed the significance of its difference by statistical procedures.Result is recovery from illness 48 example, effective 153 examples, invalid 8 examples, total effective rate 96.11%.
76 examples that wherein collection of data is complete, carry out statistical analysis, satisfactory effect.Wherein one cross type adenitis equorum ill domestic animal 35 example, typicality adenitis equorum 27 example, pernicious adenitis equorum 14 example.The tracing study several months, substantially do not recur.

Claims (2)

1. one kind for the preparation of preventing and treating the adenitis equorum powder applied in adenitis equorum and abscess medicine, it is characterized in that, adenitis equorum powder component is assessed by weight, and adenitis equorum powder contains Radix Codonopsis 5 parts-8 parts, Radix Angelicae Sinensis(soaked with wine) 5 parts-9 parts, Radix Paeoniae Alba medicine 5 parts-9 parts, Pericarpium Citri Reticulatae 10 parts-15 parts, Flos Lonicerae 15 parts-20 parts, the Radix Angelicae Dahuricae 3 parts-6 parts, Flos Chrysanthemi Indici 10 parts-15 parts, parching to brown stilbene 5 parts-10 parts, Rhizoma Chuanxiong 5 parts-8 parts, Rhizoma Atractylodis Macrocephalae (parched) 5 parts-8 parts, 5 parts-8 parts, Poria, Fructus Forsythiae 15 parts-20 parts, Spina Gleditsiae 2 parts-5 parts, Radix Glycyrrhizae 5 parts-8 parts.
2. the application prevented and treated in adenitis equorum and abscess medicine prepared by adenitis equorum powder as claimed in claim 1.
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