CN104857275B - One kind treats neurasthenic Chinese medicine composition - Google Patents

One kind treats neurasthenic Chinese medicine composition Download PDF

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CN104857275B
CN104857275B CN201510273106.3A CN201510273106A CN104857275B CN 104857275 B CN104857275 B CN 104857275B CN 201510273106 A CN201510273106 A CN 201510273106A CN 104857275 B CN104857275 B CN 104857275B
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chinese medicine
medicine composition
fruit
tuber
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CN104857275A (en
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任超
台磊
鞠萍
于海霞
王洪娟
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QINGDAO 5TH PEOPLE'S HOSPITAL
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QINGDAO 5TH PEOPLE'S HOSPITAL
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Abstract

It is used to treat neurasthenic Chinese medicine composition the invention discloses one kind, belongs to the technical field for treating neurasthenic medicine.The present invention composition be:The red sage root 10 20, the Radix Astragali 6 12, rose rhodobryum herb 10 15, fushen 6 12, dogwood fruit 6 12, the fruit of Chinese wolfberry 10 15, the tuber of dwarf lilyturf 6 12, tortoiseshell 10 20, the rhizome of nutgrass flatsedge 10 20, turtle shell 6 12, hawthorn 6 12, the root bark of tree peony 48, the seed of Oriental arborvitae 10 15, amber 6 12, corydalis tuber 6 12, centipede 48, luffa 6 12, radix bupleuri 10 15, it is mass parts above.Each taste drug matching of the present invention is scientific and reasonable, brings out the best in each other, strengthening vital QI to eliminate pathogenic factors, through focus depths, specific aim prescribe medicine is carried out to the cause of disease of neurasthenia patient, has reached the purpose nursed one's health comprehensively inside of human body function, so as to fundamentally cure neurasthenia card;Its good effect, quick, cure rate is high, has no toxic side effect.

Description

One kind treats neurasthenic Chinese medicine composition
Technical field
The invention belongs to treat the technical field of neurasthenic medicine, particularly relate to a kind of neurasthenic for treating Chinese medicine composition.
Background technology
Neurasthenia(neurasthenia)It is based on spirit and somatic function debilitating symptoms, spirit is easily excited, mental Fatiguability;The imbalance of brain higher nervous activity is mainly shown as, is characterized in often feeling mental and is short of physical strength, fatiguability, Operating efficiency is low, but exists without organic disease.Giddy, headache, dim eyesight, tinnitus, palpitaition are often accompanied by, have a pain in the back, Irritable, difficulty falling asleep, dreaming often and waking easily, insomnia forgetfulness, premature ejaculation impotence can be with minor depressive or anxiety.
With the rapid development of society and the continuous quickening of people's rhythm of life, the life of people, study, operating pressure are got over Come bigger, many young men suffer from phychasthnia very early, and phychasthnia patient is more and more, and serious have impact on the strong of people Health.
At present, doctor trained in Western medicine is in terms of neurasthenia is treated, and typically with psychotherapy and takes based on Western medicine, the psychotherapy cycle It is longer, DeGrain;Western medicine mainly includes treatment insomnia, antianxiety and tranquilizing soporific and the medicine for adjusting nervous function, such as Stable, surazepam, brain tonic mixture etc.;These medicines existing defects in terms of security and dependence, side effect is bigger, holds Easily form additive and drug resistance.
Mainly controlled in terms of the traditional Chinese medical science by Chinese herbal medicines such as wild jujube cannabis capsule, pseudo-ginseng ginseng tea, lily wild jujube cannabis capsules To treat, these medicines have the effect of certain to neurasthenia, but there is also some problems, as some drug effects are slow, course for the treatment of length, Select medicine difficult, be not easy to prepare use, effect is not fairly obvious, Time of Administration length, white elephant is brought to patient and household.
The content of the invention
The present invention provide one kind treat neurasthenic Chinese medicine composition, solve treat in the prior art it is neurasthenic The problem of curative effect of medication is poor, slowly effect and side effect are big.
One kind of the present invention treats neurasthenic Chinese medicine composition, and it is mainly realized by the following technical programs 's:
The present invention is made up of the raw material of following parts by weight:Red sage root 10-20 parts, Radix Astragali 6-12 parts, rose rhodobryum herb 10-15 parts, Fu Refreshing 6-12 parts, dogwood fruit 6-12 parts, fruit of Chinese wolfberry 10-15 parts, tuber of dwarf lilyturf 6-12 part, tortoiseshell 10-20 parts, rhizome of nutgrass flatsedge 10-20 parts, turtle shell 6-12 parts, hawthorn 6-12 parts, root bark of tree peony 4-8 parts, seed of Oriental arborvitae 10-15 parts, amber 6-12 parts, corydalis tuber 6-12 parts, centipede 4-8 parts, Luffa 6-12 parts, radix bupleuri 10-15 parts.
In the Chinese medicine composition of the present invention, the red sage root:Bitter, it is slightly cold;The thoughts of returning home, Liver Channel;It is inducing meastruation to relieve menalgia with promoting blood circulation, Relieving restlessness that clears away heart-fire, the effect of cool blood to disappear carbuncle;Cure mainly chest impediment and cardialgia, gastral cavity abdomen hypochondriac pain, the accumulation of lump in the abdomen lump in the abdomen, hot numbness pain, dysphoria and insomnia, menstruation It is uncomfortable, dysmenorrhoea Amenorrhea, sore swell and ache curative.
In the Chinese medicine composition of the present invention, the Radix Astragali:Sweet, tepor;Returns spleen, lung channel;Solid table is defended with benefit, tonifying Qi and lifting yang, Promoting pus discharge and tissue regeneration, the effect of inducing diuresis for removing edema;Cure mainly treatment deficiency of vital energy weak, anorexia and loose stool, the sinking of qi of middle-jiao, rush down prolapse of the anus for a long time, spontaneous sweating, the deficiency of blood Sallow, cloudy subcutaneous ulcer is unrestrained swollen, deficiency of vital energy oedema, Heat Diabetes.
In the Chinese medicine composition of the present invention, rose rhodobryum herb:Lightly seasoned, mild-natured, slight bitter;Thoughts of returning home warp;With feeling at ease to repose and calm The effect of;Cure mainly heart disease, nervous, palpitaition, neurasthenia.
In the Chinese medicine composition of the present invention, fushen:It is sweet, mild-natured;With excreting dampness, invigorating the spleen, calming heart and other effects;Cure mainly phlegm Drink, oedema, difficult urination, diarrhea, palpitaition, dizziness.
In the Chinese medicine composition of the present invention, dogwood fruit:Property acid, taste be flat, tepor;Enter liver and kidney channel;It is puckery with tonifying the liver and kidney The effect of smart prevent prolapse;Cure mainly dizziness and tinnitus, soreness of waist and knee joint, impotence and seminal emission, enuresis frequent micturition, under uterine bleeding band, profuse sweating collapse, interior heat disappears Yearningly.
In the Chinese medicine composition of the present invention, the fruit of Chinese wolfberry:It is sweet, it is mild-natured;Return liver, kidney, lung channel;With nourishing the liver, nourshing kidney, moistening lung The effect of;Caused by liver and kidney deficiency is cured mainly, is had a dizzy spell, visually unclear, soreness and weakness of waist and knees, impotence and seminal emission, cough due to consumptive disease, quenches one's thirst and draws drink.
In the Chinese medicine composition of the present invention, the tuber of dwarf lilyturf:Sweet, the bitter of property, is slightly cold;The thoughts of returning home, lung, stomach;With nourishing Yin and promoting production of body fluid, profit The effect of lung clears away heart-fire;Dryness of the lung dry cough is cured mainly, cough for deficiency of Yin consumptive disease, larynx numbness pharyngalgia, injury thirst, Heat Diabetes, vexed insomnia, intestinal dryness is just It is secret.
In the Chinese medicine composition of the present invention, tortoiseshell:It is salty sweet, it is mild-natured;Enter the heart, spleen, liver three to pass through;With enriching yin, checking exuberance of yang, mend Kidney, the effect of strong bone;The deficiency of the kidney yin is cured mainly, hectic fever due to yin labor heat, is spitted blood, bleeding from five sense organs or subcutaneous tissue, chronic cough, seminal emission, uterine bleeding, with, pain in the back, the atrophic debility of bones, Wind formation from yin deficiency, protracted dysentery, chronic malaria, hemorrhoid, non-closure of fontanels jin infants.
In the Chinese medicine composition of the present invention, the rhizome of nutgrass flatsedge:It is sweet, mild-natured, slight bitter;Enter liver, tri-jiao channel;With soothing liver-qi stagnation, The effect of in menstruction regulating and pain relieving, qi-regulating tune;Cure mainly stagnation of QI due to depression of the liver hypochondriac pain, abdominal distention, indigestion, chest gastral cavity ruffian, irregular menstruation, Amenorrhea dysmenorrhoea, swollen breasts, qi-stagnating abdominalgia, cold hernia stomachache.
In the Chinese medicine composition of the present invention, turtle shell:Taste is salty, cold nature;Return liver and kidney channel;With nourishing and suppressing Yang, softening hard masses dissipate Knot, the effect of bringing down a fever except steaming;Cure mainly fever due to yin deficiency, the hot hectic fever due to yin of labor, endogenous deficient wind, Amenorrhea , wei lumps in the abdomen, chronic malaria malaria mother.
In the Chinese medicine composition of the present invention, hawthorn:Sour, property is sweet, tepor;Returns spleen, stomach, Liver Channel;With appetite-stimulating indigestion-relieving, change The effect of stagnant disperse accumulations, promoting blood circulation to remove blood stasis, resolving sputum promoting the circulation of qi;Cure mainly carnivorous stagnant product, a lump in the abdomen causing distension and pain, abdominal distension feeling of fullness, stasis blocking stomachache, phlegm and retained fluid, Diarrhea, discharging fresh blood stool etc..
In the Chinese medicine composition of the present invention, the root bark of tree peony:Bitter, property is pungent, is slightly cold;Enter the heart, liver and kidney channel;With purifying the blood, Huoxue San " The effect of stasis of blood;Macula haematemesis is cured mainly, amenorrhea due to stagnation of blood, sends out gesture, carbuncle sore tumefacting virus, traumatic blood stasis, deficiency of Yin hair gesture, lossless hectic fever due to yin before menstruation.
In the Chinese medicine composition of the present invention, the seed of Oriental arborvitae:It is sweet, it is mild-natured;The thoughts of returning home, kidney, large intestine channel;With bushing blood-nourishing, profit The effect of intestines defaecation;Cure mainly the diseases such as palpitation with fear, insomnia, seminal emission, night sweat, constipation.
In the Chinese medicine composition of the present invention, amber:It is sweet, it is mild-natured;The thoughts of returning home, liver, bladder warp;With tranquillizing the mind by relieving convulsion, promoting blood circulation Stagnation resolvation, the effect of promoting diuresis for stranguria;Cure mainly infantile convulsion epilepsy, Jing Bi Disorder lumps in the abdomen, postpartum stasis, blood strangury, urolithiasis.
In the Chinese medicine composition of the present invention, corydalis tuber:The pungent, bitter of property, temperature;Enter the heart, liver, spleen, lung channel;With promoting blood circulation, dissipate The stasis of blood, qi-regulating, the effect of analgesic;Cure mainly all pains of trusted subordinate's waist and knee, irregular menstruation, abdominal mass, metrorrhagia, postpartum anemic fainting, lochiorrhagia, bruise The symptoms such as damage and chest side of body, epigastric pain, closed dysmenorrhea, postpartum stasis, tumbling and swelling.
In the Chinese medicine composition of the present invention, centipede:Pungent, the tepor of property;Return liver warp;With ceases wind antispastic, dispersing pathogen accumulation, dredging collateral The effect of analgesic;Child convulsion is cured mainly, spasm of twitching, middle air port is askew, hemiplegia, lockjaw, rheumatoid arthritis stubborn, sore, scrofula, Venomous snake bite.
In the Chinese medicine composition of the present invention, luffa:It is cool in nature, it is sweet;Enter lung, stomach, Liver Channel;With wind-dispelling, dredging collateral, clearly The effect of heat, cool blood and hemostasis;Cure mainly numbness pain contraction, distending pain in the chest and hypochondrium, alactation.
In the Chinese medicine composition of the present invention, radix bupleuri:Bitter, it is slightly cold;Return liver, gallbladder channel;With with inducing diaphoresis, soothing the liver, rising Yang The effect of;Cure mainly cold, fever, fevers and chills alternate, distending pain in the chest and hypochondrium, irregular menstruation, sub-official prolapses, prolapse of the anus.
Preferably, Chinese medicine composition of the invention is made up of the raw material of following parts by weight:15 parts of the red sage root, 9 parts of the Radix Astragali, Hui Xin 12 parts of grass, 9 parts of fushen, 9 parts of dogwood fruit, 12 parts of the fruit of Chinese wolfberry, 9 parts of the tuber of dwarf lilyturf, 15 parts of tortoiseshell, 15 parts of the rhizome of nutgrass flatsedge, 9 parts of turtle shell, hawthorn 9 Part, 6 parts of the root bark of tree peony, 12 parts of the seed of Oriental arborvitae, 9 parts of amber, 9 parts of corydalis tuber, 6 parts of centipede, 9 parts of luffa, 12 parts of radix bupleuri.
Specifically, in Chinese medicine composition of the invention, the formulation of the Chinese medicine composition is pill, and the pill is circle Honeyed bolus.
The usage and dosage of medicine pill of the present invention:The a diameter of 1cm of medicine pill of the present invention, weight 1g, aftermeals per ball With daily sooner or later each 1 time, 2 ball every time, 5 days are 1 course for the treatment of.
Beneficial effects of the present invention:The present invention it is inducing meastruation to relieve menalgia by the red sage root, the rhizome of nutgrass flatsedge, centipede and luffa, by the root bark of tree peony, Corydalis tuber and amber relaxing tendons and activating collaterals, feel at ease to repose by rose rhodobryum herb, fushen and the seed of Oriental arborvitae, clear by the tuber of dwarf lilyturf, the fruit of Chinese wolfberry and radix bupleuri Lung improving eyesight, by the Radix Astragali, tortoiseshell, turtle shell nourishing and suppressing Yang, it is aided with dogwood fruit and hawthorn carrys out appetite-stimulating indigestion-relieving, tonified the liver and kidney, disease of going directly Stove depths, specific aim prescribe medicine is carried out to the cause of disease of neurasthenia patient, each taste Chinese medicine material compatibility is scientific and reasonable, mutually benefits It is evident, strengthening vital QI to eliminate pathogenic factors, reach the purpose nursed one's health comprehensively inside of human body function, so as to fundamentally cure neurasthenia Card.The Chinese medicine composition is selected from natural Chinese medicine material, and it is prepared, and easy, medicine source is wide, cost is low, mild in medicine property and, taste is fitted In, the taste without bitterness, gentle easily clothes, greatly reduce economy and the psychological burden of patient;Good effect, quick, cure rate Height, have no toxic side effect.
Embodiment
Technical scheme is clearly and completely described below in conjunction with specific embodiment, it is clear that described Embodiment be only part of the embodiment of the present invention, rather than whole embodiment.Based on the embodiment in the present invention, ability The every other embodiment that domain those of ordinary skill is obtained under the premise of creative work is not made, belongs to guarantor of the present invention The scope of shield.
One kind treats neurasthenic Chinese medicine composition, is made up of the raw material of following parts by weight:Red sage root 10-20 parts, the Radix Astragali 6-12 parts, rose rhodobryum herb 10-15 parts, fushen 6-12 parts, dogwood fruit 6-12 parts, fruit of Chinese wolfberry 10-15 parts, tuber of dwarf lilyturf 6-12 part, tortoiseshell 10- 20 parts, rhizome of nutgrass flatsedge 10-20 parts, turtle shell 6-12 parts, hawthorn 6-12 parts, root bark of tree peony 4-8 parts, seed of Oriental arborvitae 10-15 parts, amber 6-12 parts, Corydalis tuber 6-12 parts, centipede 4-8 parts, luffa 6-12 parts, radix bupleuri 10-15 parts.
Further, Chinese medicine composition of the invention, it is made up of the raw material of following parts by weight:15 parts of the red sage root, 9 parts of the Radix Astragali, 12 parts of rose rhodobryum herb, 9 parts of fushen, 9 parts of dogwood fruit, 12 parts of the fruit of Chinese wolfberry, 9 parts of the tuber of dwarf lilyturf, 15 parts of tortoiseshell, 15 parts of the rhizome of nutgrass flatsedge, 9 parts of turtle shell, 9 parts of hawthorn, 6 parts of the root bark of tree peony, 12 parts of the seed of Oriental arborvitae, 9 parts of amber, 9 parts of corydalis tuber, 6 parts of centipede, 9 parts of luffa, 12 parts of radix bupleuri.
Further, in Chinese medicine composition of the invention, the formulation of the Chinese medicine composition is pill, and the pill is Circular honeyed bolus.
Embodiment one
One kind treats neurasthenic Chinese medicine composition, is made up of following raw material:Red sage root 10g, Radix Astragali 6g, rose rhodobryum herb 10g, Fushen 6g, dogwood fruit 6g, fruit of Chinese wolfberry 10g, tuber of dwarf lilyturf 6g, tortoiseshell 10g, rhizome of nutgrass flatsedge 10g, turtle shell 6g, hawthorn 6g, root bark of tree peony 4g, cedar seed Benevolence 10g, amber 6g, corydalis tuber 6g, centipede 4g, luffa 6g, radix bupleuri 10g.
Certainly, pill can be made in Chinese medicine composition of the invention, and other formulations can also be made, as granule, decoction, Capsule, tablet or oral liquid etc..Daily sooner or later each 1 time, one after each meal, 5 days are 1 course for the treatment of.
Embodiment two
One kind treats neurasthenic Chinese medicine composition, takes red sage root 15g, Radix Astragali 9g, rose rhodobryum herb 12g, fushen 9g, dogwood fruit 9g, fruit of Chinese wolfberry 12g, tuber of dwarf lilyturf 9g, tortoiseshell 15g, rhizome of nutgrass flatsedge 15g, turtle shell 9g, hawthorn 9g, root bark of tree peony 6g, seed of Oriental arborvitae 12g, amber 9g, Corydalis tuber 9g, centipede 6g, luffa 9g, radix bupleuri 12g, it is standby.
By above-mentioned raw materials attrition grinding, it is well mixed, adds honey, pill is made, the pill is circular honeyed bolus, its diameter Size is 1cm, is 1g per ball weight, and each taking 2 balls, one after each meal, daily sooner or later each 1 time, 5 days are 1 course for the treatment of.
Certainly, other formulations can also be made in Chinese medicine composition of the invention, as granule, decoction, capsule, tablet or Oral liquid etc..
Embodiment three
One kind treats neurasthenic Chinese medicine composition, is made up of following raw material:Red sage root 20g, Radix Astragali 12g, rose rhodobryum herb 15g, fushen 12g, dogwood fruit 12g, fruit of Chinese wolfberry 15g, tuber of dwarf lilyturf 12g, tortoiseshell 20g, rhizome of nutgrass flatsedge 20g, turtle shell 12g, hawthorn 12g, pellet Skin 8g, seed of Oriental arborvitae 15g, amber 12g, corydalis tuber 12g, centipede 8g, luffa 12g, radix bupleuri 15g.
Certainly, Chinese medicine composition of the invention can be pill, other formulations can also be made, such as granule, decoction, glue Wafer, tablet or oral liquid etc..Daily sooner or later each 1 time, one after each meal, 5 days are 1 course for the treatment of.
The present invention is expanded on further with reference to specific test example, wherein, include the present invention Chinese medicine composition animal Toxicity test, pharmacodynamics test and clinical observation experiment.
Animal toxicity test
The embodiment of the present invention one is arrived to the Chinese medicine composition of embodiment three, has carried out multiple animal toxicity test respectively;Often During secondary experiment, rabbit 20 is taken, male and female dual-purpose, body weight 1.8-2.3kg, is divided into two groups, every group 10, one of which is overdose Test group, another group is normal amount test group, and overdose test group dosage is 8.0g/kg, and normal amount test group dosage is 2.0g/ Kg, administering mode are administered for administration by gavage, and each 1 time of morning and evening, continuously takes 10 days daily, the reaction of observation administration daily;Test of many times Result shows, two groups of rabbit spirit, activity, diet, excretion are normal;Cut open inspection, main inside internal organs are visually examined, not See exception;Therefore, the Chinese medicine composition is without bad toxic side effect.
Animal pharmacodynamics test
The research of sleep of the Chinese medicine composition to mouse of the present invention, memory and antifatigue effect
1st, to the influence of mouse sleep time
Kunming mouse 60 is taken, male and female half and half, body weight 18-22g, is randomly divided into 6 groups, every group 10;Wherein, one Control group, five administration groups, the physiological saline of control group gavage same volume, the embodiment of the present invention one arrive the administration of embodiment three Group, certain commercially available neurasthenic Chinese medicine administration group for the treatment of, commercially available wild jujube seed soft capsule administration group.Successive administration 7d, one time a day, After last dose 1h, yellow Jackets 45mg/kg is injected intraperitoneally;Observation mouse righting reflex loss and recovery time, record are slept Sleep the duration, observe 2h altogether, the length of one's sleep more than 2h person, is calculated with 2h.
2nd, to the influence of mouse memory power
Kunming mouse 60 is taken, male and female half and half, body weight 18-22g, is randomly divided into 6 groups, every group 10;Wherein, one Control group, five administration groups, the physiological saline of control group gavage same volume, the embodiment of the present invention one arrive the administration of embodiment three Group, certain commercially available neurasthenic Chinese medicine administration group for the treatment of, commercially available wild jujube seed soft capsule administration group.Successive administration 7d, one time a day, After last dose 1h, mouse is put into water maze automatic recording instrument after hyoscine solution 5mg/kg, 10min is injected intraperitoneally; The time that observation mouse is gone up on the stage from starting point to the end, it is repeated 4 times, per minor tick 20s, averages and carry out statistical analysis.
3rd, to the influence of mouse anti-reflecting fatigue effect
Kunming mouse 60 is taken, male and female half and half, body weight 18-22g, is randomly divided into 6 groups, every group 10;Wherein, one Control group, five administration groups, the physiological saline of control group gavage same volume, the embodiment of the present invention one arrive the administration of embodiment three Group, certain commercially available neurasthenic Chinese medicine administration group for the treatment of, commercially available wild jujube seed soft capsule administration group.Successive administration 7d, last dose After 1h, mouse is placed in glass jar went swimming, depth of water 20cm by mouse tail root beam 2g lead respectively, and water temperature keeps 25 ± 0.5 ℃;Record swimming time, when mouse head submerged 10s can not the person of emerging be that muscle power is exhausted, timing at once is small Mouse swimming time.
4th, interpretation of result
The Chinese medicine composition of the present invention and the commercially available neurasthenic medicine for the treatment of to mouse sleep time, memory and resist tired The influence result of work is as shown in table 1.As can be seen from Table 1, compared with control group, Chinese medicine composition of the invention and commercially available The length of one's sleep of mouse can be extended to some extent by treating neurasthenic medicine, to memory impairment mould caused by hyoscine Type mouse has the function that to repair memory, and can be obviously prolonged the walking weight load of mouse.It is neurasthenic with commercially available treatment Medicine group is that certain commercially available neurasthenic Chinese medicine administration group for the treatment of is compared with commercially available wild jujube seed soft capsule administration group, in of the invention Drug composition, it is stronger to the syngignoscism of mouse, to the memory repair ability of memory impairment model mice caused by hyoscine More preferably, the walking weight load of mouse is longer.Therefore, Chinese medicine composition of the invention is more commercially available treats neurasthenic medicine more With advantage, particularly improve the memory of mouse and the antifatigue effect of enhancing mouse.
Influence result of 1 medicine of the present invention of table to mouse sleep time, memory and antifatigue effect
Group Size of animal(Only) Dosage(g/Kg) The length of one's sleep(min) Go up on the stage the time(s) Walking weight load(min)
Embodiment one 10 1 63.5±13.6** 50.0±17.9** 4.08±0.21**
Embodiment two 10 1 64.8±12.9** 49.1±18.2** 4.24±0.12**
Embodiment three 10 1 64.0±12.5** 49.7±19.8** 4.10±0.17**
Commercially available Chinese medicine group 10 1 58.7±12.4** 60.5±22.3** 3.80±0.36**
Wild jujube Capsules group 10 1 56.5±11.6** 72.6±23.8** 3.63±0.34**
Control group 10 --- 41.6±13.2 100.2±24.5 3.25±0.46
Remarks:Compared with control group, * * --- P<0.01.
Clinical observation is tested
Patient data
The neurasthenia card patient 500 of 15-60 year is randomly selected, wherein, man 200, female 300, average age is 35.6 years old, the course of disease 3 months to 10 years, average course of disease 5.6 years;The last fortnight of experiment, Continuous Observation is carried out to the crowd, records disease Shape and change, be divided into five groups according to the method for M-F, ratio of age and course of disease balanced proportion, respectively two control groups and Three treatment groups, every group each 100, there is no otherness statistically between five groups of patients, five groups of patients meet nerve Weak diagnostic criteria;This five groups of patients once use the treatment methods such as Western medicine or Chinese medicine before this treatment is received, still, Effect is not notable, easily recurrence, it is impossible to except root.
Diagnostic criteria
Cure:All symptoms all disappear, and main Physico-chemical tests index is normal;
It is effective:Symptomatology eliminates or cardinal symptom eliminates, and Physico-chemical tests index is normal;
Effectively:Cardinal symptom disappears substantially, and main Physico-chemical tests index makes moderate progress;
It is invalid:Main Physico-chemical tests index with treat before it is unchanged.
Therapeutic scheme
Control group one:Patient takes certain neurasthenic Chinese medicine of commercially available treatment orally respectively, and it is decoction, one after each meal, often Days 2 times, each 50mL, 2 weeks are 1 course for the treatment of, continuously take 3 courses for the treatment of;
Control group two:Patient takes the neurasthenic wild jujube seed soft capsule of certain commercially available treatment orally respectively, and it is capsule, meal After take, 2 times a day, 2 tablets each time, 1 week is 1 course for the treatment of, continuously takes 3 courses for the treatment of;
Treatment group:Patient takes the embodiment of the present invention one orally to three kinds of Chinese medicine compositions of embodiment three respectively, one after each meal, 2 times a day, 5 days are 1 course for the treatment of, continuously take 3 courses for the treatment of.
Daily follow-up once, is evaluated respectively before medication and after medication, after treatment finishes, continues follow-up 3 years, treatment Before, further consultation and fill in CRF during follow-up.
All subjects must not merge during experiment using the neurasthenic medicine of any other treatment and possible shadow Ring clinical efficacy and the medicine of adverse reaction evaluation.
Therapeutic effect
Five groups of clinical treatment outcomes collect as shown in table 2.
The clinical treatment outcome summary sheet of table 2
Group Number(Example) Dosage(It is secondary) Cure(Example) It is effective(Example) Take a turn for the better(Example) It is invalid(Example) Total effective rate(%)
Embodiment one 100 2 balls 84 11 5 0 100
Embodiment two 100 2 balls 85 10 5 0 100
Embodiment three 100 2 balls 84 10 6 0 100
Control group one 100 50mL 70 18 10 2 98
Control group two 100 2 55 23 17 5 95
Clinical observation result
As can be seen from Table 2, compared with two control groups, of the invention three kinds of Chinese medicine compositions are to treating nervous breakdown The effect of fine is respectively provided with, clearly, cure rate is significantly raised for advantage, and cure rate is all effective up to 85%;Mild in medicine property and nothing Bitter peculiar smell, it is gentle easily to take, significantly reduce the pain of patient;Quick, curative effect is stable, short treating period, has no toxic side effect, sample It is simultaneous to control.
Model case
Case 1:Mr. Li, female, 45 years old, accounting, work fully occupied and it is miscellaneous, it is pressed for time, pressure is very big, causes spiritual suppression Strongly fragrant, anxiety, palpitaition, dizzy, giddy is often felt like, slow in reacting, memory is decreased obviously, it is difficult to fall asleep, dreaminess, frequent midnight Waking up to fall asleep, easy cold perspiration, and anxious state of mind is big.Insomnia or midnight revival take sedative hypnotics when can not falling asleep Thing, the state of an illness never take a turn for the better, and influence work incentive and operating efficiency.Take the Chinese medicine composition of the present invention, morning and evening each 1 It is secondary, one after each meal;After taking 1 course for the treatment of, sleep quality is improved, and insomnia number is reduced, and mood is more stable;Continue to take 1 course for the treatment of, insomnia, dizzy and palpitaition symptom disappear substantially, and sleep recovers normal;Then 1 course for the treatment of is taken, to strengthen consolidating; Follow-up 2 years, no relapse, health are fine.
Case 2:Jiang, man, 30 years old, scientific research personnel, scientific research project was more, and problem difficulty is big, and Scientific Pressure is big, often dizzy Brain is swollen, headache, and sleep quality is very poor, it is difficult to falls asleep, is diagnosed as neurasthenia.When dizzy and headache, brain tonic is taken Mind tranquilizing tablet, weak curative effect, easily recurrence, its pain can not be eradicated.The Chinese medicine composition of the present invention is taken, each 1 time sooner or later, aftermeals With;After taking 1 course for the treatment of, dizzy and headache syndromes are eased, and sleep quality is improved;Continue to take 1 course for the treatment of, it is dizzy Disappeared substantially with headache syndromes, sleep recovers normal;Then 1 course for the treatment of is taken, to strengthen consolidating;Follow-up 3 years, no relapse, The state of mind is fine.
Case 3:Mr. Wang, female, 18 years old, high school student, because lessons are various, college entrance examination is entered a higher school, pressure was excessive, psychological at full stretch, Often appearance is had a headache, brain is swollen, and insomnia and decrease of memory, absent minded, school grade is poor.Once took treatment nerve Weak traditional Chinese herbal decoction, it is inconvenient to carry, and flavour of a drug are strong, it is difficult to swallows, finally abandons taking.Take the Chinese medicine group of the present invention Compound, each 1 time sooner or later, one after each meal;After taking 1 course for the treatment of, headache and the swollen symptom of brain are eased, and sleep quality is changed It is kind;Continue to take 1 course for the treatment of, all symptoms all disappear, and sleep recovers normal, and notice is concentrated;Follow-up 1 year, no relapse, School grade steps up, and has been admitted to preferable university as what is desired.
Therefore, the beneficial effect of Chinese medicine composition of the invention is:The present invention passes through the red sage root, the rhizome of nutgrass flatsedge, centipede and sponge gourd Network is inducing meastruation to relieve menalgia, by the root bark of tree peony, corydalis tuber and amber relaxing tendons and activating collaterals, feels at ease to repose by rose rhodobryum herb, fushen and the seed of Oriental arborvitae, passes through The tuber of dwarf lilyturf, the fruit of Chinese wolfberry and radix bupleuri clearing lung-heat improving eyesight, by the Radix Astragali, tortoiseshell, turtle shell nourishing and suppressing Yang, it is aided with dogwood fruit and hawthorn disappears to whet the appetite Eat, tonify the liver and kidney, focus depths of going directly, specific aim prescribe medicine is carried out to the cause of disease of neurasthenia patient, each taste Chinese medicine material is matched somebody with somebody 5 is scientific and reasonable, brings out the best in each other, strengthening vital QI to eliminate pathogenic factors, has reached the purpose nursed one's health comprehensively inside of human body function, so as to from root Neurasthenia card is cured in sheet.The Chinese medicine composition is selected from natural Chinese medicine material, and it is prepared, and easy, medicine source is wide, cost is low, Mild in medicine property and, taste is moderate, the taste without bitterness, gentle easily clothes, greatly reduces economy and the psychological burden of patient;Curative effect Good, quick, cure rate is high, has no toxic side effect.
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all essences in the present invention God any modification, equivalent substitution and improvements made etc., should be included in the scope of the protection with principle.

Claims (3)

1. one kind treats neurasthenic Chinese medicine composition, it is characterised in that:It is made up of the raw material of following parts by weight:
Red sage root 10-20 parts, Radix Astragali 6-12 parts, rose rhodobryum herb 10-15 parts, fushen 6-12 parts, dogwood fruit 6-12 parts, fruit of Chinese wolfberry 10-15 Part, tuber of dwarf lilyturf 6-12 part, tortoiseshell 10-20 parts, rhizome of nutgrass flatsedge 10-20 parts, turtle shell 6-12 parts, hawthorn 6-12 parts, root bark of tree peony 4-8 parts, cedar seed Benevolence 10-15 parts, amber 6-12 parts, corydalis tuber 6-12 parts, centipede 4-8 parts, luffa 6-12 parts, radix bupleuri 10-15 parts.
2. the neurasthenic Chinese medicine composition for the treatment of according to claim 1, it is characterised in that:By the original of following parts by weight Material is made:
15 parts of the red sage root, 9 parts of the Radix Astragali, 12 parts of rose rhodobryum herb, 9 parts of fushen, 9 parts of dogwood fruit, 12 parts of the fruit of Chinese wolfberry, 9 parts of the tuber of dwarf lilyturf, tortoiseshell 15 Part, 15 parts of the rhizome of nutgrass flatsedge, 9 parts of turtle shell, 9 parts of hawthorn, 6 parts of the root bark of tree peony, 12 parts of the seed of Oriental arborvitae, 9 parts of amber, 9 parts of corydalis tuber, centipede 6 part, thread 9 parts of melon network, 12 parts of radix bupleuri.
3. the neurasthenic Chinese medicine composition for the treatment of according to claim 1 or 2, it is characterised in that:
The formulation of the Chinese medicine composition is pill, and the pill is circular honeyed bolus.
CN201510273106.3A 2015-05-26 2015-05-26 One kind treats neurasthenic Chinese medicine composition Expired - Fee Related CN104857275B (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101549088A (en) * 2008-04-03 2009-10-07 北京中科仁和科技有限公司 Traditional Chinese medicine for treating neurasthenia and preparation method thereof
CN101589754A (en) * 2009-07-02 2009-12-02 郭庆松 A kind of Chinese medicine health-care tea of energy calming nerves and activating blood circulation
CN103223080A (en) * 2013-05-06 2013-07-31 陕西立众制药有限公司 Traditional Chinese medicinal composition for tranquilizing mind by nourishing the heart and preparation method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101549088A (en) * 2008-04-03 2009-10-07 北京中科仁和科技有限公司 Traditional Chinese medicine for treating neurasthenia and preparation method thereof
CN101589754A (en) * 2009-07-02 2009-12-02 郭庆松 A kind of Chinese medicine health-care tea of energy calming nerves and activating blood circulation
CN103223080A (en) * 2013-05-06 2013-07-31 陕西立众制药有限公司 Traditional Chinese medicinal composition for tranquilizing mind by nourishing the heart and preparation method thereof

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