CN104857210A - Traditional Chinese medicine combination preparation for treating fatty liver and preparation method thereof - Google Patents
Traditional Chinese medicine combination preparation for treating fatty liver and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine combination preparation for treating fatty liver and a preparation method thereof, and belongs to the technical field of traditional Chinese medicine. The effective constituents of the traditional Chinese medicine combination preparation comprises the following raw materials: artichoke leaves, silkworm chrysalis, Chinese wolfberries, oenothera biennis seeds, glossy ganoderma, rhizoma alismatis, silybum marianum, amorphophallus konjac, leaves of amaranthus caudatus, cassia seeds, rice-shell, artemisia lactiflora, swertia bimaculata, radix cynanchi auriculati, eucommia leaves, ampelopsis grmsedntarac, drooping stringbush flower root and bark and viscum coloratum. The traditional Chinese medicine combination preparation for treating fatty liver is reasonable in prescription, good in effect, convenient to use, good in absorption effect, is free of adverse, toxic or side effects, has an excellent therapeutic effect on fatty liver by clinical verifications and is suitable for fatty liver clinical treating and nursing popularization and application.
Description
Technical field
The invention belongs to technical field of Chinese medicines, be specifically related to a kind of Chinese medicine composition preparation for the treatment of fatty liver and preparation method thereof.
Background technology
Fatty liver, refers to the pathological changes due to overheap fatty in the hepatocyte that a variety of causes causes.Along with living standards of the people improve, dietary structure changes, the absorption level of animal food improves, the sickness rate of fatty liver is in rising trend, and the health of the positive serious threat compatriots of fatty liver disease, becomes the second largest hepatopathy being only second to viral hepatitis, be acknowledged as the common cause of disguised liver cirrhosis, final progress is the End-stage liver disease such as liver cirrhosis, brings harm, so more and more come into one's own to the health of broad masses of the people.
Summary of the invention
The invention provides a kind of Chinese medicine composition preparation for the treatment of fatty liver and preparation method thereof; Chinese medicine preparation prescription of the present invention is reasonable, and effect is good, easy to use, good absorbing effect, without bad and toxic and side effects, through clinical verification, has excellent therapy effect to fatty liver, is suitable for fatty liver clinical treatment and nursing is applied.
For achieving the above object, technical scheme of the present invention is implemented as follows.
Treat a Chinese medicine composition preparation for fatty liver, raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Cynara scolymus L (Cyhara cardunculus.) leaf 63 ~ 93 parts of Pupa bombycises 58 ~ 88 parts of Fructus Lycii 56 ~ 86 parts of seed of Radix Oenotherae erythrosepalae 53 ~ 83 parts
Ganoderma 51 ~ 81 portions of Rhizoma Alismatis 47 ~ 77 parts of Herba Silybi marianis 44 ~ 74 portions of Rhizoma amorphophallis 43 ~ 73 parts
Love-lies-bleeding leaf 40 ~ 70 parts of Semen Cassiaes 38 ~ 68 parts of olives 36 ~ 66 parts of Herba artemisiae lactifloraes 32 ~ 62 parts
22 ~ 52 parts, Herba Swertiae bimaculatae 30 ~ 60 portions of Radix Cynanchi Auriculatis 28 ~ 58 parts of Folium Eucommiaes 25 ~ 55 parts of Ampelopsis grossedentata leaves
Flos Wikstroemiae Nutantis 22 ~ 52 parts of Herba Viscis 20 ~ 50 parts.
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Cynara scolymus L (Cyhara cardunculus.) leaf 90 parts of Pupa bombycises 85 parts of Fructus Lycii 83 parts of seed of Radix Oenotherae erythrosepalae 80 parts
Ganoderma 78 portions of Rhizoma Alismatis 75 parts of Herba Silybi marianis 70 portions of Rhizoma amorphophallis 69 parts
Love-lies-bleeding leaf 67 parts of Semen Cassiaes 65 parts of olives 65 parts of Herba artemisiae lactifloraes 59 parts
48 parts, Herba Swertiae bimaculatae 57 portions of Radix Cynanchi Auriculatis 55 parts of Folium Eucommiaes 51 parts of Ampelopsis grossedentata leaves
Flos Wikstroemiae Nutantis 48 parts of Herba Viscis 46 parts.
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Cynara scolymus L (Cyhara cardunculus.) leaf 78 parts of Pupa bombycises 73 parts of Fructus Lycii 80 parts of seed of Radix Oenotherae erythrosepalae 68 parts
Ganoderma 65 portions of Rhizoma Alismatis 60 parts of Herba Silybi marianis 59 portions of Rhizoma amorphophallis 58 parts
Love-lies-bleeding leaf 55 parts of Semen Cassiaes 53 parts of olives 51 parts of Herba artemisiae lactifloraes 47 parts
37 parts, Herba Swertiae bimaculatae 45 portions of Radix Cynanchi Auriculatis 33 parts of Folium Eucommiaes 40 parts of Ampelopsis grossedentata leaves
Flos Wikstroemiae Nutantis 37 parts of Herba Viscis 35 parts.
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Cynara scolymus L (Cyhara cardunculus.) leaf 70 parts of Pupa bombycises 65 parts of Fructus Lycii 63 parts of seed of Radix Oenotherae erythrosepalae 60 parts
Ganoderma 58 portions of Rhizoma Alismatis 55 parts of Herba Silybi marianis 50 portions of Rhizoma amorphophallis 50 parts
Love-lies-bleeding leaf 48 parts of Semen Cassiaes 46 parts of olives 43 parts of Herba artemisiae lactifloraes 39 parts
28 parts, Herba Swertiae bimaculatae 37 portions of Radix Cynanchi Auriculatis 35 parts of Folium Eucommiaes 32 parts of Ampelopsis grossedentata leaves
Flos Wikstroemiae Nutantis 29 parts of Herba Viscis 27 parts.
Treat a preparation method for the Chinese medicine composition preparation of fatty liver, comprise following processing step:
(1) by Cynara scolymus L (Cyhara cardunculus.) leaf, Fructus Lycii, Rhizoma Alismatis, Herba Silybi mariani, Rhizoma amorphophalli, love-lies-bleeding leaf, Semen Cassiae, Herba Swertiae bimaculatae, Radix Cynanchi Auriculati, Folium Eucommiae, Ampelopsis grossedentata leaf, Flos Wikstroemiae Nutantis, Herba Visci decontamination, be placed in container, add the distilled water of 5 ~ 10 times, 60 DEG C of lixiviates are after 3 ~ 5 hours, boil 1 ~ 2 hour, obtain extracting solution, filter, obtain filtrate, filtrate is concentrated into the extractum that relative density is 1 ~ 1.3, be cooled to room temperature, ultraviolet radiation sterilizing, for subsequent use;
(2) get Pupa bombycis, seed of Radix Oenotherae erythrosepalae, olive, Herba artemisiae lactiflorae decontamination, microwave drying, pulverized 80 mesh sieves, load in extraction kettle, adopt supercritical CO
2abstraction technique extracts, and control extracting pressure 35 MPa, extraction temperature 30 DEG C, separation temperature 35 DEG C, extraction time 1 ~ 2 hour, obtains extract, extract is concentrated into the extractum that relative density is 1 ~ 1.3, is cooled to room temperature, ultraviolet radiation sterilizing, for subsequent use;
(3) get Ganoderma decontamination, microwave drying, pulverize, cross 160 order fine powders, ultraviolet radiation sterilizing, for subsequent use;
(4) by the extractum of step (1) gained, after fully mixing with the extractum of step (2) gained and the fine powder of step (3) gained, can add or not add pharmaceutically acceptable adjuvant (disintegrating agent, binding agent etc.) and make various dosage form, as powder, granule, mixture etc., be the Chinese medicine composition preparation for the treatment of fatty liver of the present invention.
The property of medicine of the present invention's Chinese medicine used is as follows.
Cynara scolymus L (Cyhara cardunculus.) leaf: be the leaf of feverfew Cynara scolymus L (Cyhara cardunculus.), sweet in the mouth, property is put down; 'Shugan Lidan ', lets out clearly damp and hot, main jaundice, and born of the same parents coerce distending pain, damp-heat dysentery.Begin to be loaded in " Jiangsu flora ", " Xinhua's book on Chinese herbal medicine outline " carries: " Cynara scolymus L (Cyhara cardunculus.) leaf is used for hepatitis ".
Pupa bombycis: sweet in the mouth, salty, property is put down; Return spleen, stomach warp.Infantile malnutrition is treated, promoting the production of body fluid to quench thirst, main pulmonary tuberculosis, infantile malnutrition for parasite killing." medical center bun will " carries: " and taste, curing rheumatism, long yang-energy ".
Fructus Lycii: sweet in the mouth, property is put down.Return liver, kidney channel.Nourishing the liver and kidney, replenishing vital essence to improve eyesight.For asthenia damage of essence, soreness of waist and knee joint, vertigo and tinnitus, interior-heat is quenched one's thirst, blood deficiency and yellow complexion, and blurred vision is failed to understand." key medicine divides agent " carries: " enter liver, stomach two warp, double enter lung meridian ".
Seed of Radix Oenotherae erythrosepalae: bitter in the mouth, micro-pungent, micro-sweet, property is put down.Promoting blood circulation to remove obstruction in the collateral; Endogenous wind stopping suppressing the hyperactive liver; Detumescence sore.
Ganoderma: sweet in the mouth, property is put down.GUIXIN, lung, liver, kidney channel.Invigorating QI and tranquilization, relieving cough and asthma.For dizzy sleeplessness, shortness of breath and palpitation, asthenia cough with asthma.
Rhizoma Alismatis: sweet in the mouth, cold in nature.Return kidney, urinary bladder channel.Diuresis, clearing away damp-heat.For dysuria, edema distension, oliguria of having loose bowels, dizziness due to fluid-retention, the puckery pain of pyretic stranguria; Hyperlipidemia.
Herba Silybi mariani: bitter in the mouth, cold in nature.Clearing away heat-damp and promoting diuresis; Depressed liver-energy dispersing and function of gallbladder promoting.Main chronic hepatitis; Liver cirrhosis fatty liver; Cholelithiasis; Cholangitis." Xinhua's book on Chinese herbal medicine outline " carries: " have the function of removing toxic substances.For jaundice, liver cirrhosis, hepatomegaly and other hepatopathys, cholelithiasis ".
Rhizoma amorphophalli: acrid in the mouth, hardship, cold in nature.Transforming phlegm and dispersing accumulations; Detoxicating and resolving stagnation of pathogens; Clots absorbing pain relieving.
Love-lies-bleeding leaf: removing toxic substances and promoting subsidence of swelling.Main furuncle furuncle and phyma; Contained Folium hydrangeae strigosae alkali, to having blood pressure lowering, lipotropy.
Semen Cassiae: sweet in the mouth, hardship, salty, cold nature.Return liver, kidney channel.Liver heat removing, improving eyesight, diuretic, relieving constipation.Control hypertension, hepatitis, cirrhotic ascites, habitual constipation.
Olive: mildly bitter flavor, property is put down.Loosening bowel to relieve constipation, removing toxic substances sore, main dryness of the intestine constipation, hypertension, hyperlipidemia, coronary heart disease etc.
Herba artemisiae lactiflorae: acrid in the mouth, micro-hardship, slightly warm in nature.Promoting blood circulation to remove blood stasis; Regulating QI to expel dampness.Main dysmenorrhea due to blood stasis, chronic hepatitis, hepatosplenomegaly, cold-damp is had loose bowels, and carbuncle of yin nature swells and ache.
Herba Swertiae bimaculatae: bitter in the mouth, cold in nature.Main heat clearing away, stomach invigorating, dampness removing, controls dyspepsia, gastritis, jaundice.
Radix Cynanchi Auriculati: bitter in the mouth, sweet, puckery, slightly warm in nature; Return liver,kidney,spleen stomach warp.Invigorating the liver and kidney, bone and muscle strengthening, benefiting essence-blood, strengthening the spleen to promote digestion, detoxification sore treatment." Shandong Chinese medicine " carries: " be nourishing, strong, hematonic, and can restrain vital essence, crow must hair color.Control prolonged illness weakness, anemia, early whitening of beard and hair, chronic migratory arthralgia, soreness of the waist and knees, sexual neurasthenie, hemorrhoid, enterorrhagia deficiency of YIN chronic malaria, ulcer does not close up for a long time.Fresh and have the effect of loosening bowel to relieve constipation, be applicable to old people constipation ".
Folium Eucommiae: taste is micro-pungent, warm in nature.Return liver, kidney channel.Invigorating the liver and kidney, bone and muscle strengthening, blood pressure lowering.Main lumbar and back pain; Foot knees soreness is weak; Hypertension.
Ampelopsis grossedentata leaf: bitter in the mouth, micro-puckery, cool in nature.Clearing away heat-damp and promoting diuresis; Suppressing the hyperactive liver blood pressure lowering; Promoting blood circulation to remove obstruction in the collateral.Main dysentery; Have loose bowels; Urine leaching pain; Hypertension; Dizzy order is swollen.
Flos Wikstroemiae Nutantis: sweet in the mouth, property are flat.Return liver, kidney channel.The liver and the kidney tonifying; Improving eyesight; Hemostasis; Eliminating damp, detoxifying.Main lumbocrural pain, jaundice, skin ulcer tinea.
Herba Visci: bitter in the mouth, sweet, property is put down.Return liver, kidney channel.Control invigorating the liver and kidney; Bone and muscle strengthening; Wind-damp dispelling.Main soreness of waist and knee joint; Rheumatic arthralgia.
The present invention compared with prior art, has following beneficial effect:
(1) selected by Chinese medicine preparation of the present invention, medical material compatibility is suitable, and meet Chinese medicine and pharmacy and modern medicine theory, ingredients complements each other, to fatty liver Be very effective, safe and reliable, treating both the principal and secondary aspects of a disease, wide popularization and application on clinic;
(2) with the preparation method ratio of prior art, preparation method of the present invention is simple, and be applicable to suitability for industrialized production, extraction efficiency is high.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1.
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and parts by weight are:
Cynara scolymus L (Cyhara cardunculus.) leaf 90 parts of Pupa bombycises 85 parts of Fructus Lycii 83 parts of seed of Radix Oenotherae erythrosepalae 80 parts
Ganoderma 78 portions of Rhizoma Alismatis 75 parts of Herba Silybi marianis 70 portions of Rhizoma amorphophallis 69 parts
Love-lies-bleeding leaf 67 parts of Semen Cassiaes 65 parts of olives 65 parts of Herba artemisiae lactifloraes 59 parts
48 parts, Herba Swertiae bimaculatae 57 portions of Radix Cynanchi Auriculatis 55 parts of Folium Eucommiaes 51 parts of Ampelopsis grossedentata leaves
Flos Wikstroemiae Nutantis 48 parts of Herba Viscis 46 parts.
The preparation method of Chinese medicine composition preparation of the present invention, comprises following processing step:
(1) by Cynara scolymus L (Cyhara cardunculus.) leaf, Fructus Lycii, Rhizoma Alismatis, Herba Silybi mariani, Rhizoma amorphophalli, love-lies-bleeding leaf, Semen Cassiae, Herba Swertiae bimaculatae, Radix Cynanchi Auriculati, Folium Eucommiae, Ampelopsis grossedentata leaf, Flos Wikstroemiae Nutantis, Herba Visci decontamination, be placed in container, add the distilled water of 5 ~ 10 times, 60 DEG C of lixiviates are after 3 ~ 5 hours, boil 1 ~ 2 hour, obtain extracting solution, filter, obtain filtrate, filtrate is concentrated into the extractum that relative density is 1 ~ 1.3, be cooled to room temperature, ultraviolet radiation sterilizing, for subsequent use;
(2) get Pupa bombycis, seed of Radix Oenotherae erythrosepalae, olive, Herba artemisiae lactiflorae decontamination, microwave drying, pulverized 80 mesh sieves, load in extraction kettle, adopt supercritical CO
2abstraction technique extracts, and control extracting pressure 35 MPa, extraction temperature 30 DEG C, separation temperature 35 DEG C, extraction time 1 ~ 2 hour, obtains extract, extract is concentrated into the extractum that relative density is 1 ~ 1.3, is cooled to room temperature, ultraviolet radiation sterilizing, for subsequent use;
(3) get Ganoderma decontamination, microwave drying, pulverize, cross 160 order fine powders, ultraviolet radiation sterilizing, for subsequent use;
(4) by the extractum of step (1) gained, after fully mixing with the extractum of step (2) gained and the fine powder of step (3) gained, can add or not add pharmaceutically acceptable adjuvant (disintegrating agent, binding agent etc.) and make various dosage form, as powder, granule, mixture etc., be the Chinese medicine composition preparation for the treatment of fatty liver of the present invention.
Usage and dosage: oral, every day 3 times, the morning, noon and afternoon, respectively once each 2 15 days was a course for the treatment of, and usual 2 ~ 3 courses for the treatment of are effective, and severe patient is followed the doctor's advice the meal with wine amount of adding.
Embodiment 2.
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and parts by weight are:
Cynara scolymus L (Cyhara cardunculus.) leaf 78 parts of Pupa bombycises 73 parts of Fructus Lycii 80 parts of seed of Radix Oenotherae erythrosepalae 68 parts
Ganoderma 65 portions of Rhizoma Alismatis 60 parts of Herba Silybi marianis 59 portions of Rhizoma amorphophallis 58 parts
Love-lies-bleeding leaf 55 parts of Semen Cassiaes 53 parts of olives 51 parts of Herba artemisiae lactifloraes 47 parts
37 parts, Herba Swertiae bimaculatae 45 portions of Radix Cynanchi Auriculatis 33 parts of Folium Eucommiaes 40 parts of Ampelopsis grossedentata leaves
Flos Wikstroemiae Nutantis 37 parts of Herba Viscis 35 parts.
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 3.
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and parts by weight are:
Cynara scolymus L (Cyhara cardunculus.) leaf 70 parts of Pupa bombycises 65 parts of Fructus Lycii 63 parts of seed of Radix Oenotherae erythrosepalae 60 parts
Ganoderma 58 portions of Rhizoma Alismatis 55 parts of Herba Silybi marianis 50 portions of Rhizoma amorphophallis 50 parts
Love-lies-bleeding leaf 48 parts of Semen Cassiaes 46 parts of olives 43 parts of Herba artemisiae lactifloraes 39 parts
28 parts, Herba Swertiae bimaculatae 37 portions of Radix Cynanchi Auriculatis 35 parts of Folium Eucommiaes 32 parts of Ampelopsis grossedentata leaves
Flos Wikstroemiae Nutantis 29 parts of Herba Viscis 27 parts.
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Clinical data.
1, case selection:
Select 100 routine patients to carry out clinical observation, in patient age 30-55 year, the course of disease is many in 2 to 3 years, 38 years old mean age, all has uncomfortable liver area in various degree, abdominal distention, weak, dizzy, the nauseating and symptom such as uncomfortable of defecating.Confirm have fatty liver to exist through ultrasound diagnosis.
2, medicament selection:
Treatment group patient takes Chinese medicine preparation of the present invention, oral, every day 3 times, and the morning, noon and afternoon, respectively once each 2 15 days was a course for the treatment of, takes 2 courses for the treatment of.
3, efficacy determination:
(1) cure: B ultrasonic display fatty liver disappears, and rate and blood-lipid decreased is to normal range, and liver function is normal, transference cure;
(2) effective: B ultrasonic display fatty liver degree alleviates, ALT decline > 20%, rate and blood-lipid decreased > 10%, and symptom takes a turn for the better;
(3) invalid: B ultrasonic display fatty liver degree is unchanged, and rate and blood-lipid decreased < 10%, ALT decline < 20%, symptom is without alleviating.
4, result:
Result: in 100 routine patients, cures 80 examples (80%), effective 14 examples (14%), and invalid 6 examples (6%), total effective rate is 94%.
5, model case:
Wu XX, man, 42 years old, Xiangxi phoenix people, body weight 90 kilograms before treatment, symptom was limbs fatigue, the soreness of waist, abdominal distention, hepatic region twinge, and through B ultrasonic display hepatosplenomegaly, be diagnosed as severe fatty liver, after taking 3 courses for the treatment of of Chinese medicine preparation of the present invention, all diseases all disappear.B ultrasonic display liver recovers normal, detects blood lipids index and has also recovered normal level, the transference cure of limbs fatigue, lose weight 15 kilograms, waistline reduces 10 centimetres;
Dragon XX, female, 45 years old, yueyang, hunan people, body weight 85 kilograms before treatment, was diagnosed as fatty liver, transaminase's severe overweight through B ultrasonic display, and has hyperlipidemia, and after taking 2 courses for the treatment of of Chinese medicine preparation of the present invention, all diseases all disappear.B ultrasonic display liver recovers normal, detects transaminase's index and recovers normal, lose weight 8 kilograms.
Claims (5)
1. treat a Chinese medicine composition preparation for fatty liver, it is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Cynara scolymus L (Cyhara cardunculus.) leaf 63 ~ 93 parts of Pupa bombycises 58 ~ 88 parts of Fructus Lycii 56 ~ 86 parts of seed of Radix Oenotherae erythrosepalae 53 ~ 83 parts
Ganoderma 51 ~ 81 portions of Rhizoma Alismatis 47 ~ 77 parts of Herba Silybi marianis 44 ~ 74 portions of Rhizoma amorphophallis 43 ~ 73 parts
Love-lies-bleeding leaf 40 ~ 70 parts of Semen Cassiaes 38 ~ 68 parts of olives 36 ~ 66 parts of Herba artemisiae lactifloraes 32 ~ 62 parts
22 ~ 52 parts, Herba Swertiae bimaculatae 30 ~ 60 portions of Radix Cynanchi Auriculatis 28 ~ 58 parts of Folium Eucommiaes 25 ~ 55 parts of Ampelopsis grossedentata leaves
Flos Wikstroemiae Nutantis 22 ~ 52 parts of Herba Viscis 20 ~ 50 parts.
2. according to a kind of Chinese medicine composition preparation for the treatment of fatty liver described in claim 1, it is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Cynara scolymus L (Cyhara cardunculus.) leaf 90 parts of Pupa bombycises 85 parts of Fructus Lycii 83 parts of seed of Radix Oenotherae erythrosepalae 80 parts
Ganoderma 78 portions of Rhizoma Alismatis 75 parts of Herba Silybi marianis 70 portions of Rhizoma amorphophallis 69 parts
Love-lies-bleeding leaf 67 parts of Semen Cassiaes 65 parts of olives 65 parts of Herba artemisiae lactifloraes 59 parts
48 parts, Herba Swertiae bimaculatae 57 portions of Radix Cynanchi Auriculatis 55 parts of Folium Eucommiaes 51 parts of Ampelopsis grossedentata leaves
Flos Wikstroemiae Nutantis 48 parts of Herba Viscis 46 parts.
3. according to a kind of Chinese medicine composition preparation for the treatment of fatty liver described in claim 1, it is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Cynara scolymus L (Cyhara cardunculus.) leaf 78 parts of Pupa bombycises 73 parts of Fructus Lycii 80 parts of seed of Radix Oenotherae erythrosepalae 68 parts
Ganoderma 65 portions of Rhizoma Alismatis 60 parts of Herba Silybi marianis 59 portions of Rhizoma amorphophallis 58 parts
Love-lies-bleeding leaf 55 parts of Semen Cassiaes 53 parts of olives 51 parts of Herba artemisiae lactifloraes 47 parts
37 parts, Herba Swertiae bimaculatae 45 portions of Radix Cynanchi Auriculatis 33 parts of Folium Eucommiaes 40 parts of Ampelopsis grossedentata leaves
Flos Wikstroemiae Nutantis 37 parts of Herba Viscis 35 parts.
4. according to a kind of Chinese medicine composition preparation for the treatment of fatty liver described in claim 1, it is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Cynara scolymus L (Cyhara cardunculus.) leaf 70 parts of Pupa bombycises 65 parts of Fructus Lycii 63 parts of seed of Radix Oenotherae erythrosepalae 60 parts
Ganoderma 58 portions of Rhizoma Alismatis 55 parts of Herba Silybi marianis 50 portions of Rhizoma amorphophallis 50 parts
Love-lies-bleeding leaf 48 parts of Semen Cassiaes 46 parts of olives 43 parts of Herba artemisiae lactifloraes 39 parts
28 parts, Herba Swertiae bimaculatae 37 portions of Radix Cynanchi Auriculatis 35 parts of Folium Eucommiaes 32 parts of Ampelopsis grossedentata leaves
Flos Wikstroemiae Nutantis 29 parts of Herba Viscis 27 parts.
5. as described in any one of Claims 1 to 4, treat a preparation method for the Chinese medicine composition preparation of fatty liver, it is characterized in that: comprise following processing step:
(1) by Cynara scolymus L (Cyhara cardunculus.) leaf, Fructus Lycii, Rhizoma Alismatis, Herba Silybi mariani, Rhizoma amorphophalli, love-lies-bleeding leaf, Semen Cassiae, Herba Swertiae bimaculatae, Radix Cynanchi Auriculati, Folium Eucommiae, Ampelopsis grossedentata leaf, Flos Wikstroemiae Nutantis, Herba Visci decontamination, be placed in container, add the distilled water of 5 ~ 10 times, 60 DEG C of lixiviates are after 3 ~ 5 hours, boil 1 ~ 2 hour, obtain extracting solution, filter, obtain filtrate, filtrate is concentrated into the extractum that relative density is 1 ~ 1.3, be cooled to room temperature, ultraviolet radiation sterilizing, for subsequent use;
(2) get Pupa bombycis, seed of Radix Oenotherae erythrosepalae, olive, Herba artemisiae lactiflorae decontamination, microwave drying, pulverized 80 mesh sieves, load in extraction kettle, adopt supercritical CO
2abstraction technique extracts, and control extracting pressure 35 MPa, extraction temperature 30 DEG C, separation temperature 35 DEG C, extraction time 1 ~ 2 hour, obtains extract, extract is concentrated into the extractum that relative density is 1 ~ 1.3, is cooled to room temperature, ultraviolet radiation sterilizing, for subsequent use;
(3) get Ganoderma decontamination, microwave drying, pulverize, cross 160 order fine powders, ultraviolet radiation sterilizing, for subsequent use;
(4) by the extractum of step (1) gained, after fully mixing with the extractum of step (2) gained and the fine powder of step (3) gained, can add or not add pharmaceutically acceptable adjuvant (disintegrating agent, binding agent etc.) and make various dosage form, as powder, granule, mixture etc., be the Chinese medicine composition preparation for the treatment of fatty liver of the present invention.
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| CN105943608A (en) * | 2016-05-11 | 2016-09-21 | 福州东星生物技术有限公司 | Lucid ganoderma liver-protecting tablet and preparation method thereof |
| CN107712224A (en) * | 2017-12-04 | 2018-02-23 | 爱可道生物科技有限公司 | A kind of globe artichoke shield courage tea and preparation method |
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| CN105943608A (en) * | 2016-05-11 | 2016-09-21 | 福州东星生物技术有限公司 | Lucid ganoderma liver-protecting tablet and preparation method thereof |
| CN107712224A (en) * | 2017-12-04 | 2018-02-23 | 爱可道生物科技有限公司 | A kind of globe artichoke shield courage tea and preparation method |
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