CN104800513A - Traditional Chinese medicine composition for treating cough variant asthma - Google Patents
Traditional Chinese medicine composition for treating cough variant asthma Download PDFInfo
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- CN104800513A CN104800513A CN201510248738.4A CN201510248738A CN104800513A CN 104800513 A CN104800513 A CN 104800513A CN 201510248738 A CN201510248738 A CN 201510248738A CN 104800513 A CN104800513 A CN 104800513A
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Abstract
The invention discloses a traditional Chinese medicine composition for treating cough variant asthma. The traditional Chinese medicine composition is prepared from the following active pharmaceutical ingredients: arrowleaf abelmoschus root, hylocereus undwithus flowers, greenish lily flowers, talinum crassifolium, mahonia bealei carr, dogwood, parnassia palustris, momordica grosvenori, ceylon helminthostachys rhizome and paederia scandens. The traditional Chinese medicine composition for treating the cough variant asthma provided by the invention has the advantages of remarkable curative effect, no side effects, high compliance of patients and the like; the traditional Chinese medicine composition decoction for treating the cough variant asthma provided by the invention is adopted for treating 34 patients four weeks; among the 34 patients, 9 patients are clinically cured, 13 patients are cured with obvious effect, 9 patients are cured effectively, 3 patients are not cured; the total effective rate is 91.2%.
Description
Technical field
The present invention relates to Chinese medicine sciemtifec and technical sphere, particularly a kind of Chinese medicine composition for the treatment of cough variant asthma.
Background technology
Cough variant asthma is the asthma of the specific type taking chronic cough as main or unique symptom, easily be misdiagnosed as chronic bronchitis and repetitive upper respiratory tract infection, cause can not be correct medication and make cough protracted course of disease, recurrent exerbation, some patients can develop into typical asthma, therefore treats extremely important timely and effectively.Western medical treatment is based on antiinflammatory, antiallergic, alleviation smooth muscle spasm etc., although successful in short-term, but inflammatory cell sustainable existence in air flue mucosa lamina propria, the normal recurrent exerbation of the state of an illness, long-term regular anti-inflammatory drug and bronchodilator must be leaned on to treat, and side effect is many, patient compliance is poor.Chinese traditional treatment respiratory system disease is evident in efficacy, has original understanding and abundant Couple herbs to primary disease.But along with air pollution increase the weight of year by year, the change of mass food and drink custom and the quickening of rhythm of life, the traditional Chinese medical science pathogeny of cough variant asthma also there occurs change.Therefore, again inquire into the traditional Chinese medical science pathogeny of cough variant asthma, the Chinese medicine preparation of research and development treatment cough variant asthma has important clinical significance.
Summary of the invention
The object of the invention is to the deficiency overcoming prior art, namely provide one to treat cough variant asthma Chinese medicine composition.
In order to realize foregoing invention object, the invention provides following technical scheme:
Treat a Chinese medicine composition for cough variant asthma, be made up of the crude drug of following mass ratio: Radix Abelmoschi Sagittifolii 8 ~ 12 parts, Herba hylotelephii erythrosticti chi spend 9 ~ 15 parts, Flos Lilii viriduli 6 ~ 12 parts, Radix Talini Paniculati 30 ~ 50 parts, Fructus Mahoniae 6 ~ 10 parts, Fructus Corni 6 ~ 10 parts, Herba parnassiae 3 ~ 9 parts, Fructus Momordicae 15 ~ 25 parts, Rhizoma Helminthostachydis Zeylanicae 9 ~ 15 parts, fevervine 20 ~ 40 parts.
The pharmacological action of raw material of Chinese medicine medicine of the present invention is as follows:
Radix Abelmoschi Sagittifolii: sweet, light, flat.Nourishing YIN and moistening the lung, and diabetes involving middle-JIAO infantile malnutrition.Cure mainly xeropulmonary cough, pulmonary tuberculosis, stomachache, infantile malnutrition, neurasthenia.
Herba hylotelephii erythrosticti chi flower: sweet, be slightly cold, returns lung meridian.Clearing heat and moistening lung, removing toxic substances and promoting subsidence of swelling.Cure mainly cough due to lung-heat, pulmonary tuberculosis, scrofula, mumps.
Flos Lilii viriduli: sweet, micro-hardship, to be slightly cold, returns liver, lung, heart channel.Clearing heat and moistening lung, mind tranquilizing and the heart calming.Cure mainly cough few expectorant or sticky, dizzy, vexed, uneasy sleeping at night, sky bleb eczema.
Radix Talini Paniculati: sweet, flat.Invigorating the spleen and replenishing QI, nourishing YIN and moistening the lung, reducing swelling and alleviating pain.Cure mainly insufficiency of the spleen lack of appetite weak, have loose bowels, proctoptosis, pulmonary tuberculosis hemoptysis, hectic fever, night sweat, spontaneous perspiration, the enuresis, hypogalactia in puerperal, carbuncle furuncle.
Fructus Mahoniae: bitter, cool.Tonifying the lung, kidney tonifying, clearind deficient heat.Cure mainly pulmonary tuberculosis, osteopyrexia and fever, spitting of blood, soreness of the waist and knees, dizziness and tinnitus, metrorrhagia, leukorrhagia, stranguria with turbid discharge.
Fructus Corni: sour, puckery, tepor, returns liver, kidney channel.Liver and kidney tonifying, restrains astringent or styptic treatment for spontaneous sweating.Cure mainly soreness of the waist and knees, dizziness and tinnitus, sexual impotence; Emission and spermatorrhea, enuresis frequent micturition; Metrorrhagia, menorrhagia; Large apogee sweating, weak body and prostration.
Herba parnassiae: bitter, cool.Clearing away heat and cooling blood, removing toxic substances and promoting subsidence of swelling, relieving cough and resolving phlegm.Cure mainly icterohepatitis, bacillary dysentery, laryngopharynx swelling and pain, vasculitis, sore and toxic, pertussis, cough with copious phlegm.
Fructus Momordicae: sweet, cool, returns lung, spleen channel.Lung heat clearing, reduces phlegm, cough-relieving, intestine moistening.Cure mainly phlegm-fire cough, pertussis, pharyngolaryngitis, tonsillitis, acute gastritis, constipation.
Rhizoma Helminthostachydis Zeylanicae: bitter, sweet, cool.Removing heat from the lung and dissipating phlegm, dissipating blood stasis detoxifies.Cure mainly cough, asthma, pharyngalgia, treating swelling and pain by traumatic injury, carbuncle skin ulcer, venom.
Fevervine: sweet, bitter, be slightly cold, returns spleen, stomach, liver, lung meridian.Promoting digestion and invigorating the stomach, preventing phlegm from forming and stopping coughing, heat-clearing and toxic substances removing, pain relieving.Cure mainly eating accumulation, infantile malnutrition; Phlegm heat cough; Pyretic toxicity dysentery, laryngopharynx swelling and pain, carbuncle furuncle swells, burn and scald etc.; Gastrointestinal distress, biliary colic, renal colic, dysmenorrhea, labor pains, neuralgia and various wound, fracture, postoperative pain etc.
According to dry cough, few symptom such as expectorant, itching throat, and the feature such as chronic delay, obstinate refractory, recurrent exerbation, cough variant asthma can belong to the category such as " cough ", " lung-QI stagnation syndrome ".Cough variant asthma patient Chang Fanfu being invaded by exogenous pathogen, pathogen retains in body, does not with the passing of time go, strongly fragrant and heat-transformation, and consumption impairment of QI is cloudy, causes deficiency of both QI and YIN, and function activity is in hyperactivity of YANG due to deficiency of YIN for a long time and pathogenic heat consumption hinders state.In addition many patient's life-time service hormones also can cause deficiency of both QI and YIN.Therefore, yin asthenia generating intrinsic heat is primary disease basic pathology feature.Lung and kidney are mother child relation, both mutual generation between metal and waters.Controlling for above pathogenesis nourishing YIN and clearing away heat to be main, and invigorating the lung and the kidney is auxiliary.The present invention adopts Radix Abelmoschi Sagittifolii, Herba hylotelephii erythrosticti chi flower, Flos Lilii viriduli nourishing YIN and moistening the lung; Radix Talini Paniculati, Fructus Mahoniae, Fructus Corni invigorating the lung and the kidney, supplementing QI and nourishing YIN; Herba parnassiae, Fructus Momordicae, Rhizoma Helminthostachydis Zeylanicae, fevervine lung heat clearing, reduce phlegm, cough-relieving, and prolonged illness must the stasis of blood, and Rhizoma Helminthostachydis Zeylanicae blood circulation promoting and blood stasis dispelling, fevervine promoting digestion and invigorating the stomach, makes QI and blood biochemistry active.All medicines share, and gather the merit of eliminating pathogenic factor for supporting vital QI altogether.
Preferably, the Chinese medicine composition of described treatment cough variant asthma is made up of the crude drug of following mass ratio: Radix Abelmoschi Sagittifolii 9 ~ 11 parts, Herba hylotelephii erythrosticti chi spend 11 ~ 13 parts, Flos Lilii viriduli 8 ~ 10 parts, Radix Talini Paniculati 35 ~ 45 parts, Fructus Mahoniae 7 ~ 9 parts, Fructus Corni 7 ~ 9 parts, Herba parnassiae 5 ~ 7 parts, Fructus Momordicae 18 ~ 22 parts, Rhizoma Helminthostachydis Zeylanicae 11 ~ 13 parts, fevervine 25 ~ 35 parts.
Further preferred, the Chinese medicine composition of described treatment cough variant asthma is made up of the crude drug of following mass ratio: Radix Abelmoschi Sagittifolii 10 parts, Herba hylotelephii erythrosticti chi spend 12 parts, Flos Lilii viriduli 10 parts, Radix Talini Paniculati 40 parts, Fructus Mahoniae 8 parts, Fructus Corni 8 parts, Herba parnassiae 6 parts, Fructus Momordicae 20 parts, Rhizoma Helminthostachydis Zeylanicae 12 parts, fevervine 30 parts.
The Chinese medicine composition of described treatment cough variant asthma can adopt existing Chinese medicine preparation technology to be prepared into any conventional oral preparations, such as can decocting be adopted to obtain water decoction said components, by other existing Chinese medicine preparation technology, the Chinese medicine composition of described treatment cough variant asthma can also be prepared into tablet, water-honeyed pill, capsule, powder, unguentum, oral liquid, granule.
compared with prior art, beneficial effect of the present invention
The advantages such as traditional Chinese medicine composition for treating cough variant asthma provided by the invention has evident in efficacy, has no side effect, and patient compliance is good.
treat a Chinese medicine composition for cough variant asthma, clinical efficacy is summed up
1 physical data
34 routine patients, wherein man 21 example, female 13 example, 17 ~ 65 years old age, the mean age (38.4 ± 11.1) year, the course of disease the shortest February, the longest 4 years.
2 diagnostic criterias
" the Clinics and Practices guide of cough " formulated with reference to respirology branch of Chinese Medical Association asthma group in 2009 [respirology branch of Chinese Medical Association asthma group. the Clinics and Practices guide (2009 editions) of cough. Chinese tuberculosis and breathe magazine, 2009,32 (6): 408-409.] diagnostic criteria of cough variant asthma in: 1. chronic cough (course of disease is greater than 8 weeks), often with obvious irritable cough at night; 2. brinchial provocation test is positive, or End--tidal PCO_2 aberration rate > 20% in the daytime, or Bronchodilation Test is positive; 3. antibiotic, cough suppressing medicine are invalid, and bronchodilators treatment effectively; 4. the chronic cough that other reasons causes is got rid of.
3 Therapeutic Method
Radix Abelmoschi Sagittifolii 10 grams, Herba hylotelephii erythrosticti chi spend 12 grams, Flos Lilii viriduli 10 grams, Radix Talini Paniculati 40 grams, Fructus Mahoniae 8 grams, Fructus Corni 8 grams, Herba parnassiae 6 grams, Fructus Momordicae 20 grams, Rhizoma Helminthostachydis Zeylanicae 12 grams, fevervine 30 grams, conveniently Chinese medicine preparation technology makes water decoction, everyone potion every day.
4 therapeutic outcomes
4.1 efficacy assessment standards: reference " new Chinese medicine guideline of clinical investigations " (Ministry of Health of the People's Republic of China. new Chinese medicine guideline of clinical investigations. Beijing: China Medical Science Press, 2002,58.) standard envisages: clinical cure: clinical symptoms, sign disappear or substantially disappear, syndrome integral reduces >=95%; Effective: clinical symptoms, sign are obviously improved, syndrome integral reduces >=70%; Effective: clinical symptoms, sign all take a favorable turn, syndrome integral reduces >=30%; Invalid: clinical symptoms, sign are all not improved, even increase the weight of, syndrome integral reduces less than 30%.Integration × 100% before therapeutic index=(before treatment the rear integration of integration-treatment)/treatment.
4.2 results: through treatment in 4 weeks, clinical cure 9 example, effective 13 examples, effective 9 examples, invalid 3 examples, total effective rate 91.2%.
Detailed description of the invention
Below in conjunction with detailed description of the invention, the present invention is described in further detail.But this should be interpreted as that the scope of the above-mentioned theme of the present invention is only limitted to following embodiment, all technology realized based on content of the present invention all belong to scope of the present invention.
Embodiment 1
A kind of Chinese medicine composition for the treatment of cough variant asthma, be by Radix Abelmoschi Sagittifolii 12 grams, Herba hylotelephii erythrosticti chi spend 15 grams, Flos Lilii viriduli 12 grams, Radix Talini Paniculati 50 grams, Fructus Mahoniae 10 grams, Fructus Corni 10 grams, Herba parnassiae 9 grams, Fructus Momordicae 25 grams, Rhizoma Helminthostachydis Zeylanicae 15 grams, fevervine 40 grams, conveniently Chinese medicine preparation technology makes water decoction, everyone potion every day.
Embodiment 2
A kind of Chinese medicine composition for the treatment of cough variant asthma, be by Radix Abelmoschi Sagittifolii 11 grams, Herba hylotelephii erythrosticti chi spend 13 grams, Flos Lilii viriduli 10 grams, Radix Talini Paniculati 45 grams, Fructus Mahoniae 9 grams, Fructus Corni 9 grams, Herba parnassiae 7 grams, Fructus Momordicae 22 grams, Rhizoma Helminthostachydis Zeylanicae 13 grams, fevervine 35 grams, conveniently Chinese medicine preparation technology makes water decoction, everyone potion every day.
Embodiment 3
A kind of Chinese medicine composition for the treatment of cough variant asthma, be by Radix Abelmoschi Sagittifolii 10 grams, Herba hylotelephii erythrosticti chi spend 12 grams, Flos Lilii viriduli 10 grams, Radix Talini Paniculati 40 grams, Fructus Mahoniae 8 grams, Fructus Corni 8 grams, Herba parnassiae 6 grams, Fructus Momordicae 20 grams, Rhizoma Helminthostachydis Zeylanicae 12 grams, fevervine 30 grams, conveniently Chinese medicine preparation technology makes water decoction, everyone potion every day.
Embodiment 4
A kind of Chinese medicine composition for the treatment of cough variant asthma, be by Radix Abelmoschi Sagittifolii 9 grams, Herba hylotelephii erythrosticti chi spend 11 grams, Flos Lilii viriduli 8 grams, Radix Talini Paniculati 35 grams, Fructus Mahoniae 7 grams, Fructus Corni 7 grams, Herba parnassiae 5 grams, Fructus Momordicae 18 grams, Rhizoma Helminthostachydis Zeylanicae 11 grams, fevervine 25 grams, conveniently Chinese medicine preparation technology makes water decoction, everyone potion every day.
Embodiment 5
A kind of Chinese medicine composition for the treatment of cough variant asthma, be by Radix Abelmoschi Sagittifolii 8 grams, Herba hylotelephii erythrosticti chi spend 9 grams, Flos Lilii viriduli 6 grams, Radix Talini Paniculati 30 grams, Fructus Mahoniae 6 grams, Fructus Corni 6 grams, Herba parnassiae 3 grams, Fructus Momordicae 15 grams, Rhizoma Helminthostachydis Zeylanicae 9 grams, fevervine 20 grams, conveniently Chinese medicine preparation technology makes water decoction, everyone potion every day.
Claims (4)
1. treat a Chinese medicine composition for cough variant asthma, it is characterized in that being made up of the crude drug of following mass ratio:
Radix Abelmoschi Sagittifolii 8 ~ 12 parts, Herba hylotelephii erythrosticti chi spend 9 ~ 15 parts, Flos Lilii viriduli 6 ~ 12 parts, Radix Talini Paniculati 30 ~ 50 parts, Fructus Mahoniae 6 ~ 10 parts, Fructus Corni 6 ~ 10 parts, Herba parnassiae 3 ~ 9 parts, Fructus Momordicae 15 ~ 25 parts, Rhizoma Helminthostachydis Zeylanicae 9 ~ 15 parts, fevervine 20 ~ 40 parts.
2. the Chinese medicine composition for the treatment of cough variant asthma as claimed in claim 1, is characterized in that being made up of the crude drug of following mass ratio:
Radix Abelmoschi Sagittifolii 9 ~ 11 parts, Herba hylotelephii erythrosticti chi spend 11 ~ 13 parts, Flos Lilii viriduli 8 ~ 10 parts, Radix Talini Paniculati 35 ~ 45 parts, Fructus Mahoniae 7 ~ 9 parts, Fructus Corni 7 ~ 9 parts, Herba parnassiae 5 ~ 7 parts, Fructus Momordicae 18 ~ 22 parts, Rhizoma Helminthostachydis Zeylanicae 11 ~ 13 parts, fevervine 25 ~ 35 parts.
3. the Chinese medicine composition for the treatment of cough variant asthma as claimed in claim 1, is characterized in that being made up of the crude drug of following mass ratio:
Radix Abelmoschi Sagittifolii 10 parts, Herba hylotelephii erythrosticti chi spend 12 parts, Flos Lilii viriduli 10 parts, Radix Talini Paniculati 40 parts, Fructus Mahoniae 8 parts, Fructus Corni 8 parts, Herba parnassiae 6 parts, Fructus Momordicae 20 parts, Rhizoma Helminthostachydis Zeylanicae 12 parts, fevervine 30 parts.
4. treat the preparation method of the Chinese medicine composition of cough variant asthma as claimed in claim 1, it is characterized in that the Chinese medicinal components of described mass ratio to be prepared into water decoction, tablet, water-honeyed pill, capsule, powder, unguentum, oral liquid, granule.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105079236A (en) * | 2015-09-16 | 2015-11-25 | 栾月华 | Lung-moistening phlegm-dispersing medicament for treating asthma and preparation method thereof |
| CN105796956A (en) * | 2016-03-29 | 2016-07-27 | 于世花 | Traditional Chinese medicine for treating cough variant asthma and preparation method thereof |
-
2015
- 2015-05-18 CN CN201510248738.4A patent/CN104800513A/en active Pending
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| 吴忆东: "中药内服配合雾化吸入治疗小儿咳嗽变异性哮喘102例", 《江苏中医药》 * |
| 支艳等: "滋阴清热补肺益肾法治疗咳嗽变异性哮喘的临床研究", 《中医临床研究》 * |
| 牛宛柯: "滋阴清热补肺益肾法治疗儿童咳嗽变异性哮喘疗效观察", 《中医临床研究》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105079236A (en) * | 2015-09-16 | 2015-11-25 | 栾月华 | Lung-moistening phlegm-dispersing medicament for treating asthma and preparation method thereof |
| CN105796956A (en) * | 2016-03-29 | 2016-07-27 | 于世花 | Traditional Chinese medicine for treating cough variant asthma and preparation method thereof |
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Application publication date: 20150729 |
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