CN103735780B - A kind of Chinese medicine preparation and preparation method for the treatment of chronic bronchitis - Google Patents
A kind of Chinese medicine preparation and preparation method for the treatment of chronic bronchitis Download PDFInfo
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Abstract
The invention discloses a kind of Chinese medicine preparation and preparation method for the treatment of chronic bronchitis, belong to the field of Chinese medicines; The raw material of Chinese medicine preparation effective ingredient of the present invention consists of: Cortex celtis bungeanae (Cortex seu Caulis Celtis Bungeane), Radix Osbeckiae Crinitae, Herba Aconiti Ochranthi, Folium Viticis Negundo, Herba Cyperi Glomerati, Bombyx Batryticatus, Herba Apii graveolentis, Winchia calophylla A. DC., Herba Solani Nigri, Herb Gynostemmae Pentaphylli, Begonia aptera Bl., Radix Polemonii Liniflori, Folium Elaeagni delavayi, Radix Gossypii, salt alkali and Herba Colei Pumili; Chinese medicine preparation of the present invention has effect of heat clearing away solution expectorant, nourishing YIN and moistening the lung, relieving cough and expelling phlegm, hypertensive tranquilizing, the symptom such as cough, expectoration, cough with asthma caused for treatment chronic bronchitis has significant curative effect, and medical material compatibility is suitable, make simple, security performance is high, taking convenience, without any side effects, the object for the treatment of both the principal and secondary aspects of a disease can be reached, clinic wide popularization and application to the treatment of chronic bronchitis.
Description
Art
The present invention relates to the field of Chinese medicines, particularly relate to a kind of Chinese medicine preparation and preparation method for the treatment of chronic bronchitis.
Background technology
Bronchitis is a kind of common chronic disease in our daily life, often first has acute upper respiratory tract infection symptom, as nasal obstruction, sneeze, pharyngalgia, hoarseness etc., only has the bronchitic symptoms such as slight fear of cold, heating, headache and systemic pain.Cough starts not weigh, and in zest, expectorant is few, aggravation of coughing after 1 ~ 2 day, and expectorant transfers coctum to by mucus; Heavier case often morning rise, Body Position Change of sleeping, after sucking cold air or physical exertion, have paroxysmal cough, sometimes cough even all day.
Bronchitis refers to the chronic nonspecific inflammation of trachea-bronchial epithelial cell mucosa and surrounding tissue thereof.Its main cause is that the repeated infection of virus and antibacterial defines bronchial chronic nonspecific inflammation.When under mercury dropped, respiratory tract small blood vessel spasm ischemia, defense function, degradation is beneficial to pathogenic, the chronic stimulations such as smog dust, atmosphere pollution also can be fallen ill, and smoking makes bronchospasm, mucilage secretion increases advantageous infectivity, and intolerance factors also has certain relation; Chronic bronchitis morbidity and acute exacerbation are common in cold season in winter, especially when weather changes suddenly, acute bronchitis with rhinorrhea, heating, cough, expectoration for cardinal symptom, and friction pain after having pharynx hoarseness, laryngalgia, slight breastbone.Initial stage expectorant is few, in viscosity, becomes purulence later, and flue dust and cold air etc. stimulate can make cough increase the weight of.
At present along with the progress and development of science and technology, the method that people treat this disease also gets more and more, the a large amount of antibiotic of main employing is as erythromycin, cephalosporins, expectorant is as TANKEJING, spasmolytic anti-asthmatic is as aminophylline etc., but these medicines are easy to produce drug resistance, not easily tackle the problem at its root, after drug withdrawal and easily recurrent exerbation, and toxic side effect.
Summary of the invention
The invention provides a kind of Chinese medicine preparation and preparation method for the treatment of chronic bronchitis, Chinese medicine preparation of the present invention has effect of heat clearing away solution expectorant, nourishing YIN and moistening the lung, relieving cough and expelling phlegm, hypertensive tranquilizing, the symptom such as cough, expectoration, cough with asthma caused for treatment chronic bronchitis has significant curative effect, and medical material compatibility is suitable, make simple, security performance is high, taking convenience, without any side effects, the object for the treatment of both the principal and secondary aspects of a disease can be reached, clinic wide popularization and application to the treatment of chronic bronchitis.
For achieving the above object, technical scheme of the present invention is implemented as follows:
Treat a Chinese medicine preparation for chronic bronchitis, raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Treat a preparation method for the Chinese medicine preparation of chronic bronchitis, comprise following processing step:
(1) Cortex celtis bungeanae (Cortex seu Caulis Celtis Bungeane), Radix Osbeckiae Crinitae, Herba Aconiti Ochranthi, Herba Cyperi Glomerati, Herba Apii graveolentis, Winchia calophylla A. DC., Herba Solani Nigri, Begonia aptera Bl., Radix Polemonii Liniflori, Folium Elaeagni delavayi and Radix Gossypii are cleaned, put into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, being condensed into relative density at 60 DEG C is the thick paste of 1.10 ~ 1.16, for subsequent use;
(2) cleaned by Folium Viticis Negundo, shady and cool place dries, and chopping, puts into container, strand juice, and filter impurity, stays juice for subsequent use;
(3) Bombyx Batryticatus, Herb Gynostemmae Pentaphylli and salt alkali are mixed, carry out pulverization process after mix homogeneously, grind into powder, cross 160 order fine powders, for subsequent use;
(4) Herba Colei Pumili is cleaned, immerse the alcohol solution dipping 3 ~ 4 hours of 85% of 8 times amount, heating and refluxing extraction 2 ~ 3 hours, reclaim ethanol, filter, by the thick paste of relative density 1.20 ~ 1.25 under filtrate simmer down to 75 DEG C of environment, for subsequent use;
(5) by thick paste, juice and the fine powder mixing obtained by above-mentioned steps (1) ~ (4), make capsule, obtain the Chinese medicine preparation for the treatment of chronic bronchitis of the present invention.
The property of medicine of the present invention's Chinese medicine used is as follows:
Cortex celtis bungeanae (Cortex seu Caulis Celtis Bungeane): acrid in the mouth, micro-hardship, cool in nature.Cough-relieving, eliminates the phlegm.Cure mainly chronic bronchitis.
Radix Osbeckiae Crinitae: sweet in the mouth, puckery, property is put down.Clearing away heat-damp and promoting diuresis, cough-relieving, regulating menstruation.For acute gastroenteritis, bacillary dysentery, dyspepsia, chronic bronchitis, spits blood, menoxenia, leucorrhea." Kweiyang medicinal herbs among the people " carry: " heat clearing away astringing to arrest bleeding.Control dysentery, void is coughed, spitting of blood.”
Herba Aconiti Ochranthi: bitter in the mouth, warm in nature, poisonous; Return liver, lung meridian.Wind-expelling pain-stopping, relieving cough and resolving phlegm, relievings asthma.Cure mainly Fengshi Guanjie to swell and ache, lumbago and skelalgia, breath with cough, scrofula, scabies." herbal classic " carries: " main body skin skin ulcer steam can be done to bathe soup.”
Folium Viticis Negundo: mildly bitter flavor, pungent, property is put down; Return lung meridian.Eliminate the phlegm, cough-relieving, relievings asthma.For cough with asthma; Chronic bronchitis." Fujian Chinese herbal medicine " carries: " expelling pathogenic wind from the body surface, regulating QI stomach function regulating.”
Herba Cyperi Glomerati: acrid in the mouth, micro-hardship, property is put down; Return lung meridian.Cough-relieving removing blood stasis, circulation of qi promoting of stimulating the menstrual flow, removing food stagnancy pain relieving.For chronic tracheitis, lump in the abdomen, postpartum stagnation is suffered from abdominal pain, dyspepsia, amenorrhea and all stagnation of QI-bloods, breast abdominal rib pain.
Bombyx Batryticatus: salty in the mouth, pungent, property is put down; Return liver, lung, stomach warp.Relieving fever and suppressing cough, reduces phlegm, calm relieving convulsion, detumescence, and regulates neural, many and lipid metabolism.Control epilepsy, hyperpyrexia convulsion, mumps, upper respiratory tract infection, chronic tracheitis, the enuresis, urticaria, high serum ornitrol etc.
Herba Apii graveolentis: sweet in the mouth, pungent, cool in nature; Enter liver, gallbladder, pericardium channel.Clearing away heat-damp and promoting diuresis, suppressing the hyperactive liver stomach invigorating.Can removing heat from the liver, nourish blood." health communication " carries: " heat is washed in clearing stomach, promoting blood circulation, and tasty and refreshing tooth wets one's whistle, improving eyesight stuffy nose relieving, refreshment stomach invigorating, nourishing the lung to arrest cough." modern medicine study confirmation, Herba Apii graveolentis contains abundant vitamin A, vitamin B1, vitamin B2, vitamin C and Citrin, calcium, ferrum, and the content of mineral substances such as phosphorus are also many, also has the compositions such as protein, mannitol and dietary fiber in addition.
Winchia calophylla A. DC.: bitter in the mouth, property is put down, mild toxicity; Return lung meridian.Relieving cough and asthma.Treating acute and chronic bronchitis, external is stopped blooding.
Herba Solani Nigri: bitter in the mouth, cold in nature, slightly poisonous.Heat-clearing and toxic substances removing, inducing diuresis to remove edema.For cat fever, toothache, chronic bronchitis, dysentery, urinary system infection, mastitis, leucorrhea, cancer; Carbuncle furuncle furuncle is controlled in external, pemphigus, venom." this sketch of the southern regions of the Yunnan Province is said " carries: " control children's's ailment said due to cold or exposure, heat symptom-complex infantile convulsion, spasmolytic of reducing phlegm, also controls variolar carbuncle, pruritus due to wind pathogen all over.Furuncle, can attack and can fall apart.Leaf: wash skin ulcer.”
Herb Gynostemmae Pentaphylli: bitter in the mouth, micro-sweet, cool in nature; Return lung, spleen, kidney channel.Heat clearing away, tonify deficiency, removing toxic substances.Cure mainly body void weak, nephrasthenia emission, leukopenia, hyperlipemia, viral hepatitis, chronic gastroenteritis, chronic tracheitis.
Begonia aptera Bl.: bitter in the mouth, property is put down.Clearing and antitussive, dissipating blood stasis for subsidence of swelling.Control chronic bronchitis, cough due to lung-heat, exogenous high fever, tonsillitis, pertussis, carbuncle skin ulcer is red and swollen, innominate toxic swelling, traumatic injury.
Radix Polemonii Liniflori: bitter in the mouth, property is put down; Return lung, the heart, liver, spleen, stomach warp.Eliminate the phlegm, hemostasis, calm.Control acute and chronic bronchitis, gastric hemorrhage, hemoptysis, epistaxis, metrorrhagia, epilepsy is had a sleepless night, menorrhagia." Chinese herbal medicine handbook is commonly used in Heilungkiang " carries: " control acute and chronic bronchitis, hemoptysis, spit blood, epistaxis, has blood in stool, metrorrhagia.”
Folium Elaeagni delavayi: sour in the mouth, property is put down.Diuresis and expelling stone, relieving cough and relieving asthma, promoting the circulation of QI to relieve pain.Cure mainly chronic nephritis, stomachache, chronic bronchitis, bronchial asthma.
Radix Gossypii: sweet in the mouth, warm in nature.QI invigorating, cough-relieving, relievings asthma.For chronic bronchitis, body is impractical swollen, uterine prolapse." illustrated handbook planted by middle traditional Chinese medicines " carries: " be emmenagogue (for difficult menstruation and apolipsis), hemorrhage.”
Salt alkali: salty in the mouth, hardship, warm in nature.Heart tonifying diuresis, calm antiinflammatory, blood pressure lowering.For Keshan disease, Kaschin-Beck disease, endemic goiter, rheumatic arthritis, silicosis, hypertension." Jilin Chinese herbal medicine " carries: " heart tonifying, calm, aid digestion, spasmolytic is fainted, antiinflammatory.Control chronic Keshan disease, goiter, Kaschin-Beck disease, chronic gastritis, chronic nephritis, hepatitis, chronic bronchitis, hypertension, dermatitis, tumor.”
Herba Colei Pumili: acrid in the mouth, micro-hardship, warm in nature, slightly poisonous; Return lung, liver, spleen, stomach warp.Dispelling cold by warming the meridian, expelling phlegm for arresting cough, dissipating blood stasis for subsidence of swelling.For cough due to wind and cold, chronic bronchitis, asthma, chronic gastritis, wind and cold arthralgia pain; Traumatic injury is controlled in external, venom." Guangxi Chinese herbal medicine " carries: " expelling wind and cold, antiasthmatic-antitussive, promoting the circulation of QI to relieve pain, removing toxic substances and promoting subsidence of swelling.Control cough due to wind and cold, bronchial asthma, the cold pain of abdomen, caries pain, venom, treating swelling and pain by traumatic injury.”
The present invention compared with prior art, has following beneficial effect:
Chinese medicine preparation of the present invention has effect of heat clearing away solution expectorant, nourishing YIN and moistening the lung, relieving cough and expelling phlegm, hypertensive tranquilizing, the symptom such as cough, expectoration, cough with asthma caused for treatment chronic bronchitis has significant curative effect, and medical material compatibility is suitable, make simple, security performance is high, taking convenience, without any side effects, the object for the treatment of both the principal and secondary aspects of a disease can be reached, clinic wide popularization and application to the treatment of chronic bronchitis.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
Treat a preparation method for the Chinese medicine preparation of chronic bronchitis, comprise following processing step:
(1) Cortex celtis bungeanae (Cortex seu Caulis Celtis Bungeane), Radix Osbeckiae Crinitae, Herba Aconiti Ochranthi, Herba Cyperi Glomerati, Herba Apii graveolentis, Winchia calophylla A. DC., Herba Solani Nigri, Begonia aptera Bl., Radix Polemonii Liniflori, Folium Elaeagni delavayi and Radix Gossypii are cleaned, put into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, being condensed into relative density at 60 DEG C is the thick paste of 1.10 ~ 1.16, for subsequent use;
(2) cleaned by Folium Viticis Negundo, shady and cool place dries, and chopping, puts into container, strand juice, and filter impurity, stays juice for subsequent use;
(3) Bombyx Batryticatus, Herb Gynostemmae Pentaphylli and salt alkali are mixed, carry out pulverization process after mix homogeneously, grind into powder, cross 160 order fine powders, for subsequent use;
(4) Herba Colei Pumili is cleaned, immerse the alcohol solution dipping 3 ~ 4 hours of 85% of 8 times amount, heating and refluxing extraction 2 ~ 3 hours, reclaim ethanol, filter, by the thick paste of relative density 1.20 ~ 1.25 under filtrate simmer down to 75 DEG C of environment, for subsequent use;
(5) by thick paste, juice and the fine powder mixing obtained by above-mentioned steps (1) ~ (4), make capsule, obtain the Chinese medicine preparation for the treatment of chronic bronchitis of the present invention.
Usage and dosage: oral, every day 3 times, each 1 time of morning, noon and afternoon, each 2, warm water delivery service after meal; Within 10 days, be 1 course for the treatment of, 2 ~ 4 courses for the treatment of can fully recover, and the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
Embodiment 2
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 3
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 4
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 5
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Clinical data:
1, case selection:
As the Chinese medicine preparation for the treatment of chronic bronchitis, select the routine clinical observation of chronic bronchitis patient 160 of making a definite diagnosis, patient is divided into treatment group and matched group two groups at random, treatment group 80 example, wherein male 45 example, women 35 example, 45 ~ 80 years old age, 62.5 years old mean age; Matched group 80 example, wherein male 43 example, women 37 example, 46 ~ 81 years old age, 63.5 years old mean age; The course of disease, the degrees of symptoms for the treatment of group and matched group two groups of cases are basically identical, without significant difference, have comparability.
2, medicament selection:
Treatment group takes Chinese medicine preparation of the present invention, usage and dosage: oral, every day 3 times, each 1 time of morning, noon and afternoon, each 2, warm water delivery service after meal; Within 10 days, be 1 course for the treatment of, taking 2 ~ 4 courses for the treatment of continuously can fully recover, and the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
Matched group uses amoxicillin sodium for injection sulbactam sodium, intravenous drip, and after dissolving with the appropriate water for injection of front use or sodium chloride injection, then add 0.9% sodium chloride injection 100ml iv drip, each instillation time is no less than 30 ~ 40 minutes.Adult human dose: each 0.75 ~ 1.5g, every day 3 ~ 4 times.Dosage can be increased according to the state of an illness, but sulbactam maximal dose every day can not more than 4.0g.
3, efficacy determination:
(1) cure: the transference cures such as cough, expectoration, cough with asthma, in routine blood test, leukocyte transfers to normally, and chest sign and x ray examination focus local are obviously improved and disappear completely.
(2) effective: the symptoms such as cough, expectoration, cough with asthma obviously alleviate, and lesions position obviously improves and is tending towards normal.
(3) invalid: the symptoms such as cough, expectoration, cough with asthma are without improvement or increase the weight of.
4, result:
Above result display, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.
Model case is illustrated:
1, Dong, man, 48 years old, Zhenjiang, Jiangsu people.Patient suffers from more than 2 years of chronic bronchitis, cough, and asthma increases the weight of 10 days, coughs yellow sputum.C-XF shows: thorax is full, two enhanced lung markings, and lung field transmittance strengthens, and two diaphragm is low flat, and heart is in position of hanging down.Diagnosing chronic bronchitis sign.Take medicine after 1 course for the treatment of by taking Drug therapy of the present invention, cough, asthma symptom is clearly better, and after taking 2 courses for the treatment of, cough, asthma symptom disappears, recovery from illness.
2, Xu certain, female, 55 years old, Ningbo of Zhejiang people.Chronic is coughed, companion's asthma 5 years, and within nearly 3 days, increase the weight of to accompany expectoration, breast CT shows chronic bronchitis sign.After taking 1 course for the treatment of of Drug therapy of the present invention, cough, expectoration symptom are clearly better, and after taking 2 courses for the treatment of of medicine of the present invention, symptom disappears substantially, and after taking 3 courses for the treatment of of medicine of the present invention, recovery from illness, follows up a case by regular visits to after 1 year without recurrence.
3, Cao, female, 63 years old, Heze City, Shandong Province people.In more than 10 years of Chronic bronchitis medical history, within nearly 3 days, there is cough, asthma and expectoration, and cardiopalmus, edema of lower limbs.C-XF is property bronchitis sign.After taking 1 course for the treatment of of Drug therapy of the present invention, cough, asthma and expectoration symptom obviously alleviate, and after taking 2 courses for the treatment of of medicine of the present invention, cough, asthma and expectoration symptom disappear substantially, and after taking 3 courses for the treatment of of medicine of the present invention, recovery from illness, follows up a case by regular visits to after half a year without recurrence.
4, Liao, man, 71 years old, people from Fushun., recently there is expectoration, heating in Chronic cough, companion's asthma 6 years.C-XF is diagnosed: meet chronic bronchitis.After taking 1 course for the treatment of of Drug therapy of the present invention, expectoration, heating paresthesia alleviate to some extent, and after taking for 2 courses for the treatment of, expectoration symptom disappears substantially, and body temperature is replied normal, fully recovers after taking 3 courses for the treatment of.
5, certain is apt to, man, 30 years old, people from Linyi, Shandong.Entire patient feels cold, and hyperpyrexia burns about 40 degree, is all dusk dusk on foot, after the hospital that makes a return journey bought some conventional coldrexs, take a couple of days, to no effect, have clinic to have an intravenous drip, sb.'s illness took a favorable turn, but after drug withdrawal, recur again, patient is diagnosed as the concurrent chronic bronchitis of flu after carrying out my institute's inspection, take medicine of the present invention same day, temperature recovery is normal, takes 3 courses for the treatment of, conditions of patients is completely recovered, and has no recurrence.
6, together certain, female, 27 years old, Yushu district, Qinghai people.Patient previously suffered from influenza, and sensation nasal blockage, has hemorrhage sometimes, the dry pain of throat, and with a little thick sputum, take Ke Li can behind coldrex and antibiotic medicine, amoxicillin the state of an illness slightly well, after again repeatedly, admission examination display is with bronchitis inflammation symptom.Take 2 courses for the treatment of of Chinese medicine preparation of the present invention, the state of an illness is fully recovered, and has no recurrence.
Claims (5)
1. treat a Chinese medicine preparation for chronic bronchitis, it is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Cortex celtis bungeanae (Cortex seu Caulis Celtis Bungeane) 41 ~ 76 parts of Radix Osbeckiae Crinitaes 36 ~ 65 parts of Herba Aconiti Ochranthi 34 ~ 63 parts of Folium Viticis Negundo 35 ~ 56 parts
Herba Cyperi Glomerati 30 ~ 60 parts of Bombyx Batryticatus 30 ~ 55 portions of Herba Apii graveolentis 26 ~ 55 parts of Winchia calophylla A. DC. 25 ~ 50 parts
Herba Solani Nigri 24 ~ 49 portions of Herb Gynostemmae Pentaphylli 20 ~ 49 parts of Begonia aptera Bl. 19 ~ 49 Fen Radix Polemonii Liniflori 15 ~ 50 parts
Folium Elaeagni delavayi 14 ~ 45 parts of Radix Gossypiis 12 ~ 44 parts of salt alkali 12 ~ 39 parts of Herba Colei Pumilis 10 ~ 35 parts.
2. a kind of Chinese medicine preparation for the treatment of chronic bronchitis according to claim 1, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Cortex celtis bungeanae (Cortex seu Caulis Celtis Bungeane) 47 ~ 70 parts of Radix Osbeckiae Crinitaes 41 ~ 60 parts of Herba Aconiti Ochranthi 39 ~ 57 parts of Folium Viticis Negundo 40 ~ 52 parts
Herba Cyperi Glomerati 35 ~ 55 parts of Bombyx Batryticatus 35 ~ 50 portions of Herba Apii graveolentis 31 ~ 50 parts of Winchia calophylla A. DC. 29 ~ 46 parts
Herba Solani Nigri 29 ~ 44 portions of Herb Gynostemmae Pentaphylli 25 ~ 44 parts of Begonia aptera Bl. 24 ~ 44 Fen Radix Polemonii Liniflori 20 ~ 45 parts
Folium Elaeagni delavayi 19 ~ 40 parts of Radix Gossypiis 16 ~ 38 parts of salt alkali 17 ~ 34 parts of Herba Colei Pumilis 14 ~ 30 parts.
3. a kind of Chinese medicine preparation for the treatment of chronic bronchitis according to claim 1, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Cortex celtis bungeanae (Cortex seu Caulis Celtis Bungeane) 53 ~ 64 parts of Radix Osbeckiae Crinitaes 46 ~ 55 parts of Herba Aconiti Ochranthi 45 ~ 51 parts of Folium Viticis Negundo 45 ~ 49 parts
Herba Cyperi Glomerati 40 ~ 50 parts of Bombyx Batryticatus 40 ~ 45 portions of Herba Apii graveolentis 36 ~ 45 parts of Winchia calophylla A. DC. 33 ~ 42 parts
Herba Solani Nigri 34 ~ 39 portions of Herb Gynostemmae Pentaphylli 30 ~ 39 parts of Begonia aptera Bl. 29 ~ 39 Fen Radix Polemonii Liniflori 26 ~ 38 parts
Folium Elaeagni delavayi 24 ~ 35 parts of Radix Gossypiis 22 ~ 32 parts of salt alkali 22 ~ 30 parts of Herba Colei Pumilis 18 ~ 26 parts.
4. a kind of Chinese medicine preparation for the treatment of chronic bronchitis according to claim 1, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Cortex celtis bungeanae (Cortex seu Caulis Celtis Bungeane) 59 parts of Radix Osbeckiae Crinitaes 51 parts of Herba Aconiti Ochranthi 48 parts of Folium Viticis Negundo 47 parts
Herba Cyperi Glomerati 45 parts of Bombyx Batryticatus 43 portions of Herba Apii graveolentis 40 parts of Winchia calophylla A. DC. 38 parts
Herba Solani Nigri 37 portions of Herb Gynostemmae Pentaphylli 35 parts of Begonia aptera Bl. 34 Fen Radix Polemonii Liniflori 32 parts
Folium Elaeagni delavayi 30 parts of Radix Gossypiis 27 parts of salt alkali 26 parts of Herba Colei Pumilis 22 parts.
5. as described in any one of Claims 1 to 4, treat a preparation method for the Chinese medicine preparation of chronic bronchitis, it is characterized in that: comprise following processing step:
(1) Cortex celtis bungeanae (Cortex seu Caulis Celtis Bungeane), Radix Osbeckiae Crinitae, Herba Aconiti Ochranthi, Herba Cyperi Glomerati, Herba Apii graveolentis, Winchia calophylla A. DC., Herba Solani Nigri, Begonia aptera Bl., Radix Polemonii Liniflori, Folium Elaeagni delavayi and Radix Gossypii are cleaned, put into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, being condensed into relative density at 60 DEG C is the thick paste of 1.10 ~ 1.16, for subsequent use;
(2) cleaned by Folium Viticis Negundo, shady and cool place dries, and chopping, puts into container, strand juice, and filter impurity, stays juice for subsequent use;
(3) Bombyx Batryticatus, Herb Gynostemmae Pentaphylli and salt alkali are mixed, carry out pulverization process after mix homogeneously, grind into powder, cross 160 order fine powders, for subsequent use;
(4) Herba Colei Pumili is cleaned, immerse the alcohol solution dipping 3 ~ 4 hours of 85% of 8 times amount, heating and refluxing extraction 2 ~ 3 hours, reclaim ethanol, filter, by the thick paste of relative density 1.20 ~ 1.25 under filtrate simmer down to 75 DEG C of environment, for subsequent use;
(5) by thick paste, juice and the fine powder mixing obtained by above-mentioned steps (1) ~ (4), make capsule, obtain the Chinese medicine preparation of described treatment chronic bronchitis.
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| CN103446445A (en) * | 2013-09-03 | 2013-12-18 | 解明芸 | Traditional Chinese medicine preparation for treating qi-yin deficiency-type chronic bronchitis and preparation method thereof |
| CN103520550A (en) * | 2013-10-23 | 2014-01-22 | 吴嫱 | Traditional Chinese medicine for treating external cold internal rheum type chronic bronchitis and preparation method thereof |
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| CN103446445A (en) * | 2013-09-03 | 2013-12-18 | 解明芸 | Traditional Chinese medicine preparation for treating qi-yin deficiency-type chronic bronchitis and preparation method thereof |
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