CN104800369A - Traditional Chinese medicine liquid for treating oral ulcer and preparation method of traditional Chinese medicine liquid - Google Patents
Traditional Chinese medicine liquid for treating oral ulcer and preparation method of traditional Chinese medicine liquid Download PDFInfo
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Abstract
The invention relates to a traditional Chinese medicine liquid for treating oral ulcer and a preparation method of the traditional Chinese medicine liquid. The traditional Chinese medicine liquid is prepared from raw materials in parts by weight as follows: 12-21 parts of siraitia grosvenori, 12-18 parts of euchresta japonica, 6-12 parts of roughhaired holly root, 9-15 parts of mint, 6-13 parts of liquorice, 8-18 parts of goldthread root, 4-9 parts of Chinese angelica, 5-11 parts of lonicera japonica, 200-600 parts of water, 3-7 parts of heartleaf houttuynia herb, 5-12 parts of dahurian patrinia herb and 6-9 parts of asarum. The traditional Chinese medicine liquid for treating oral ulcer is prepared by combining vacuum micro-wave drying, freezing drying and mechanical crushing performed on traditional Chinese medicine materials; the prepared traditional Chinese medicine liquid can be prepared from pure traditional Chinese medicines, can be taken as decoction, can be also used for external application, has a good treatment effect and takes effect quickly; oral ulcer cannot relapse; the open part of a sore cannot be uncomfortable during external application.
Description
Technical field
The present invention relates to kind of a Chinese medicine for the treatment of ulcer, be specifically related to a kind of Chinese medicinal aqua for the treatment of oral ulcer and preparation method thereof.
Background technology
Oral ulcer (also known as scorching in aphtha, mouth) refers to the mucosa at the soft tissue places such as lip, tongue cheek and palate in oral cavity, occur single or multiple yellow-white circular or oval fester a little, on the feed, drink water, brush teeth, touch ulcer place when even speaking and all can feel obvious pain or burning sensation, the easy recurrent exerbation of some patient.Due to the difference of site of pathological change, local symptom, term has again the titles such as dispute skin ulcer, mouth are broken, aphtha, mouth infections.Primary disease is one of modal disease in oral mucosa, common with person between twenty and fifty, is equivalent to recurrent oral ulceration, is again recurrent aphthous stomatitis.In between twenty and fifty period, the triggering of a lot of oral ulcer, be all result from once or several times process on the feed in, the mistake of tooth to oral mucosa inwall or tongue superficial epithelium tissue and connective tissue chews injury, because the antibacterial in oral cavity is a lot, antibacterial enters connective tissue that wound site exposes and complicated biological agent and chemical action occurs and forms ulcer wound surface, thus forms oral ulcer.But this is one of a kind of Crack cause of oral ulcer, the existence of the oral ulcer questions and prospect that the pathogenic factor not getting rid of other causes.
Good oral hygiene can reduce the incidence rate of oral ulcer, and absorbing vitamin B12, ferrum, zinc and folic acid in addition also has certain effect.If oral ulcer has and obviously evitablely brings out main cause, as do not conformed to the artificial tooth of mouth shape or tooth set, food anaphylaxis, overexertion etc. of brushing teeth, avoid these inducements fundamentally can reduce the recurrence of oral ulcer.But the oral ulcer of the overwhelming majority is casual oral wounds to be caused, as food stab, tooth stings by mistake, the prevention for this inducement is unactual.Longevity of service, extended sleep deficiency in addition, easily cause endocrine disturbance and immunity degradation, have a meal if often go out, diet is unbalanced, also may not necessarily absorb enough vitamin Cs and E, can increase the chance of " raw flying is grown ".Many people to eat the fragrant mouth pearl of sugar-free after the meal, and in addition, clinical experiment confirms the stimulation in the rote of fragrant mouth pearl and the sense of taste, and the secretory volume that can increase saliva reaches more than four times, and saliva has and rinses the mouth and antibacterial effectiveness, helps and keeps oral cavity cleaning and health.If therefore eating the fragrant mouth pearl of sugar-free containing vitamin C and vitamin E after the meal, can help and prevent decayed tooth and nourish tooth meat, very applicable rhythm of life people rapidly.
License publication number be the disclosure of the invention of CN102872247A treatment oral ulcer Chinese medicine, composition comprises: Rhizoma Coptidis, Cortex Phellodendri, Olibanum, Myrrha, Cortex Cinnamomi, Calamina, Sanguis Draxonis, Borneolum Syntheticum, Margarita, five OS DRACONISs, Galla Chinensis, Borax, Radix Glycyrrhizae and Indigo Naturalis, the Chinese medicine that this invention obtains has cures soon, short treating period, the advantage not easily recurred more; But the rear open sore part of its use there will be the scorching hot discomfort that waits reacts.
Summary of the invention
The object of the invention is to provide a kind of Chinese medicinal aqua for the treatment of oral ulcer and preparation method thereof to overcome above the deficiencies in the prior art.
Technical scheme: the invention discloses a kind of Chinese medicinal aqua for the treatment of oral ulcer, the Chinese medicinal aqua of described treatment cavity ulcer is made up by weight of following raw material: Fructus Momordicae 12 ~ 21 parts, Radix Sophorae Tonkinensis 12 ~ 18 parts, Radix Ilicis Asprellae 6 ~ 12 parts, Herba Menthae 9 ~ 15 parts, 6 ~ 13 parts, Radix Glycyrrhizae, Rhizoma Coptidis 8 ~ 18 parts, Radix Angelicae Sinensis 4 ~ 9 parts, Flos Lonicerae 5 ~ 11 parts and 200 ~ 600 parts, water.
Preferably, described a kind of Chinese medicinal aqua for the treatment of oral ulcer, the Chinese medicinal aqua of described treatment cavity ulcer is made up by weight of following raw material: Fructus Momordicae 12 ~ 21 parts, Radix Sophorae Tonkinensis 12 ~ 18 parts, Radix Ilicis Asprellae 6 ~ 12 parts, Herba Menthae 9 ~ 15 parts, 6 ~ 13 parts, Radix Glycyrrhizae, Rhizoma Coptidis 8 ~ 18 parts, Radix Angelicae Sinensis 4 ~ 9 parts, Flos Lonicerae 5 ~ 11 parts, 200 ~ 600 parts, water, Herba Houttuyniae 3 ~ 7 parts, Herba Patriniae 5 ~ 12 parts and Herba Asari 6 ~ 9 parts.
Preferably, described a kind of Chinese medicinal aqua for the treatment of oral ulcer, the Chinese medicinal aqua of described treatment cavity ulcer is made up by weight of following raw material: Fructus Momordicae 15 ~ 17 parts, Radix Sophorae Tonkinensis 14 ~ 16 parts, Radix Ilicis Asprellae 8 ~ 10 parts, Herba Menthae 11 ~ 13 parts, 7 ~ 11 parts, Radix Glycyrrhizae, Rhizoma Coptidis 12 ~ 14 parts, Radix Angelicae Sinensis 5 ~ 8 parts, Flos Lonicerae 6 ~ 9 parts, 300 ~ 500 parts, water, Herba Houttuyniae 4 ~ 6 parts, Herba Patriniae 7 ~ 10 parts and Herba Asari 6 ~ 8 parts.
Preferably, described a kind of Chinese medicinal aqua for the treatment of oral ulcer, the Chinese medicinal aqua of described treatment cavity ulcer is made up by weight of following raw material: Fructus Momordicae 16 parts, Radix Sophorae Tonkinensis 15 parts, Radix Ilicis Asprellae 9 parts, Herba Menthae 12 parts, 9 parts, Radix Glycyrrhizae, Rhizoma Coptidis 13 parts, Radix Angelicae Sinensis 6 parts, Flos Lonicerae 7 parts, 400 parts, water, Herba Houttuyniae 5 parts, Herba Patriniae 8 parts and Herba Asari 7 parts.
A preparation method for the Chinese medicinal aqua for the treatment of oral ulcer and preparation method thereof, comprises the steps:
Step one, cleans all medical materials with clear water;
Step 2, first Fructus Momordicae, Radix Sophorae Tonkinensis, Radix Ilicis Asprellae and Herba Menthae are carried out Mechanical Crushing, after fragmentation, carry out vacuum microwave drying, respectively above-mentioned Chinese crude drug is ground after drying, get Fructus Momordicae 12 ~ 21 parts, Radix Sophorae Tonkinensis 12 ~ 18 parts, Radix Ilicis Asprellae 6 ~ 12 parts and Herba Menthae 9 ~ 15 parts after strainer filtering respectively, be mixed to get A powder;
Step 3, this several raw material of Radix Glycyrrhizae, Rhizoma Coptidis, Radix Angelicae Sinensis, Flos Lonicerae, Herba Houttuyniae, Herba Patriniae and Herba Asari is carried out Mechanical Crushing respectively, after fragmentation, carry out lyophilization, respectively above-mentioned lyophilized products is ground after drying, distinguish extracting liquorice 6 ~ 13 parts, Rhizoma Coptidis 8 ~ 18 parts, Radix Angelicae Sinensis 4 ~ 9 parts, Flos Lonicerae 5 ~ 11 parts, Herba Houttuyniae 3 ~ 7 parts, Herba Patriniae 5 ~ 12 parts and Herba Asari 6 ~ 9 parts again after strainer filtering, be mixed to get B powder;
Step 4, by A powder and the mixing of B powder, adds 200 ~ 600 parts, water and soaks 2 hours rear filtered while hot of post-heating backflow, be the Chinese medicinal aqua for the treatment of oral ulcer after the cooling of gained filtrate.
Preferably, described a kind of preparation method for the treatment of the Chinese medicinal aqua of oral ulcer, step 2 and the filter screen particle diameter described in step 3 are 200 orders.
Preferably, described a kind of preparation method for the treatment of the Chinese medicinal aqua of oral ulcer, the baking temperature of the vacuum microwave drying described in step 2 is 45 DEG C, and vacuum is 100Pa, and microwave power is 800w.
Preferably, described a kind of preparation method for the treatment of the Chinese medicinal aqua of oral ulcer, the cryodesiccated baking temperature described in step 3 is-15 DEG C, and sublimation drying is 4 hours.
Preferably, described a kind of preparation method for the treatment of the Chinese medicinal aqua of oral ulcer, the heating-up temperature of the reflux described in step 4 is 105 DEG C, and the time is 3 hours.
Beneficial effect: due to the disorder of daily life system and the irregular of diet, usually can cause and get angry and then cause oral ulcer.The present invention uses pure Chinese drug preparation to obtain, and can be used as that decoction takes also can external application, and therapeutic effect is good, and onset time is fast, not easily causes recurrence, and the open sore part can not be made during external application to have uncomfortable sensation.When Fructus Momordicae 16 parts, Radix Sophorae Tonkinensis 15 parts, Radix Ilicis Asprellae 9 parts, Herba Menthae 12 parts, 9 parts, Radix Glycyrrhizae, Rhizoma Coptidis 13 parts, Radix Angelicae Sinensis 6 parts, Flos Lonicerae 7 parts, 400 parts, water, Herba Houttuyniae 5 parts, Herba Patriniae 8 parts and Herba Asari 7 parts time, the best results of Chinese medicinal aqua for the treatment of oral ulcer.
Detailed description of the invention
Embodiment 1
Step one, with all medical materials of the clean water of 20 DEG C;
Step 2, first Fructus Momordicae, Radix Sophorae Tonkinensis, Radix Ilicis Asprellae and Herba Menthae are carried out Mechanical Crushing, after fragmentation, carry out vacuum microwave drying, temperature is 45 DEG C, and vacuum is 100Pa, microwave power is 800w, respectively above-mentioned Chinese crude drug is ground after drying, be get Fructus Momordicae 12 parts, Radix Sophorae Tonkinensis 18 parts, Radix Ilicis Asprellae 6 parts and Herba Menthae 15 parts respectively after 200 object strainer filterings with particle diameter, be mixed to get A powder;
Step 3, this several raw material of Radix Glycyrrhizae, Rhizoma Coptidis, Radix Angelicae Sinensis, Flos Lonicerae, Herba Houttuyniae, Herba Patriniae and Herba Asari is carried out Mechanical Crushing respectively, after fragmentation, carry out lyophilization, temperature is-15 DEG C, and the time is 4 hours, is ground by above-mentioned lyophilized products respectively after drying, distinguish extracting liquorice 6 parts, Rhizoma Coptidis 18 parts, Radix Angelicae Sinensis 4 parts, Flos Lonicerae 11 parts, Herba Houttuyniae 3 parts, Herba Patriniae 12 parts and Herba Asari 6 parts again after strainer filtering, be mixed to get B powder;
Step 4, by A powder and the mixing of B powder, adds 200 parts, water and soaks after 2 hours, and outer temperature 105 DEG C is heated to backflow filtered while hot after 3 hours, is the Chinese medicinal aqua for the treatment of oral ulcer after the cooling of gained filtrate.
Embodiment 2
Step one, with all medical materials of the clean water of 20 DEG C;
Step 2, first Fructus Momordicae, Radix Sophorae Tonkinensis, Radix Ilicis Asprellae and Herba Menthae are carried out Mechanical Crushing, after fragmentation, carry out vacuum microwave drying, temperature is 45 DEG C, and vacuum is 100Pa, microwave power is 800w, respectively above-mentioned Chinese crude drug is ground after drying, be get Fructus Momordicae 21 parts, Radix Sophorae Tonkinensis 12 parts, Radix Ilicis Asprellae 12 parts and Herba Menthae 9 parts respectively after 200 object strainer filterings with particle diameter, be mixed to get A powder;
Step 3, this several raw material of Radix Glycyrrhizae, Rhizoma Coptidis, Radix Angelicae Sinensis, Flos Lonicerae, Herba Houttuyniae, Herba Patriniae and Herba Asari is carried out Mechanical Crushing respectively, after fragmentation, carry out lyophilization, temperature is-15 DEG C, and the time is 4 hours, is ground by above-mentioned lyophilized products respectively after drying, distinguish extracting liquorice 13 parts, Rhizoma Coptidis 8 parts, Radix Angelicae Sinensis 9 parts, Flos Lonicerae 5 parts, Herba Houttuyniae 7 parts, Herba Patriniae 5 parts and Herba Asari 9 parts again after strainer filtering, be mixed to get B powder;
Step 4, by A powder and the mixing of B powder, adds 600 parts, water and soaks after 2 hours, and outer temperature 105 DEG C is heated to backflow filtered while hot after 3 hours, is the Chinese medicinal aqua for the treatment of oral ulcer after the cooling of gained filtrate.
Embodiment 3
Step one, with all medical materials of the clean water of 20 DEG C;
Step 2, first Fructus Momordicae, Radix Sophorae Tonkinensis, Radix Ilicis Asprellae and Herba Menthae are carried out Mechanical Crushing, after fragmentation, carry out vacuum microwave drying, temperature is 45 DEG C, and vacuum is 100Pa, microwave power is 800w, respectively above-mentioned Chinese crude drug is ground after drying, be get Fructus Momordicae 15 parts, Radix Sophorae Tonkinensis 16 parts, Radix Ilicis Asprellae 8 parts and Herba Menthae 13 parts respectively after 200 object strainer filterings with particle diameter, be mixed to get A powder;
Step 3, this several raw material of Radix Glycyrrhizae, Rhizoma Coptidis, Radix Angelicae Sinensis, Flos Lonicerae, Herba Houttuyniae, Herba Patriniae and Herba Asari is carried out Mechanical Crushing respectively, after fragmentation, carry out lyophilization, temperature is-15 DEG C, and the time is 4 hours, is ground by above-mentioned lyophilized products respectively after drying, distinguish extracting liquorice 7 parts, Rhizoma Coptidis 14 parts, Radix Angelicae Sinensis 5 parts, Flos Lonicerae 9 parts, Herba Houttuyniae 4 parts, Herba Patriniae 10 parts and Herba Asari 6 parts again after strainer filtering, be mixed to get B powder;
Step 4, by A powder and the mixing of B powder, adds 300 parts, water and soaks after 2 hours, and outer temperature 105 DEG C is heated to backflow filtered while hot after 3 hours, is the Chinese medicinal aqua for the treatment of oral ulcer after the cooling of gained filtrate.
Embodiment 4
Step one, with all medical materials of the clean water of 20 DEG C;
Step 2, first Fructus Momordicae, Radix Sophorae Tonkinensis, Radix Ilicis Asprellae and Herba Menthae are carried out Mechanical Crushing, after fragmentation, carry out vacuum microwave drying, temperature is 45 DEG C, and vacuum is 100Pa, microwave power is 800w, respectively above-mentioned Chinese crude drug is ground after drying, be get Fructus Momordicae 17 parts, Radix Sophorae Tonkinensis 14 parts, Radix Ilicis Asprellae 10 parts and Herba Menthae 11 parts respectively after 200 object strainer filterings with particle diameter, be mixed to get A powder;
Step 3, this several raw material of Radix Glycyrrhizae, Rhizoma Coptidis, Radix Angelicae Sinensis, Flos Lonicerae, Herba Houttuyniae, Herba Patriniae and Herba Asari is carried out Mechanical Crushing respectively, after fragmentation, carry out lyophilization, temperature is-15 DEG C, and the time is 4 hours, is ground by above-mentioned lyophilized products respectively after drying, distinguish extracting liquorice 11 parts, Rhizoma Coptidis 12 parts, Radix Angelicae Sinensis 8 parts, Flos Lonicerae 6 parts, Herba Houttuyniae 6 parts, Herba Patriniae 7 parts and Herba Asari 8 parts again after strainer filtering, be mixed to get B powder;
Step 4, by A powder and the mixing of B powder, adds 500 parts, water and soaks after 2 hours, and outer temperature 105 DEG C is heated to backflow filtered while hot after 3 hours, is the Chinese medicinal aqua for the treatment of oral ulcer after the cooling of gained filtrate.
Embodiment 5
Step one, with all medical materials of the clean water of 20 DEG C;
Step 2, first Fructus Momordicae, Radix Sophorae Tonkinensis, Radix Ilicis Asprellae and Herba Menthae are carried out Mechanical Crushing, after fragmentation, carry out vacuum microwave drying, temperature is 45 DEG C, and vacuum is 100Pa, microwave power is 800w, respectively above-mentioned Chinese crude drug is ground after drying, be get Fructus Momordicae 16 parts, Radix Sophorae Tonkinensis 15 parts, Radix Ilicis Asprellae 9 parts and Herba Menthae 12 parts respectively after 200 object strainer filterings with particle diameter, be mixed to get A powder;
Step 3, this several raw material of Radix Glycyrrhizae, Rhizoma Coptidis, Radix Angelicae Sinensis, Flos Lonicerae, Herba Houttuyniae, Herba Patriniae and Herba Asari is carried out Mechanical Crushing respectively, after fragmentation, carry out lyophilization, temperature is-15 DEG C, and the time is 4 hours, is ground by above-mentioned lyophilized products respectively after drying, distinguish extracting liquorice 9 parts, Rhizoma Coptidis 13 parts, Radix Angelicae Sinensis 6 parts, Flos Lonicerae 7 parts, Herba Houttuyniae 5 parts, Herba Patriniae 8 parts and Herba Asari 7 parts again after strainer filtering, be mixed to get B powder;
Step 4, by A powder and the mixing of B powder, adds 400 parts, water and soaks after 2 hours, and outer temperature 105 DEG C is heated to backflow filtered while hot after 3 hours, is the Chinese medicinal aqua for the treatment of oral ulcer after the cooling of gained filtrate.
Comparative example
The invention formula being CN102872247A according to license publication number makes a kind of Chinese medicine for the treatment of oral ulcer: get Rhizoma Coptidis 40 parts, Cortex Phellodendri 40 parts, Olibanum 18 parts, Myrrha 17 parts, Cortex Cinnamomi 18 parts, Calamina 40 parts, Sanguis Draxonis 40 parts, Borneolum Syntheticum 20 parts, Margarita 18 parts, five OS DRACONIS 20 parts, Galla Chinensis 80 parts, Borax 120 parts, 40 parts, Radix Glycyrrhizae and Indigo Naturalis 40 parts, raw material pulverizing is mixed into Chinese medicine powder, Chinese medicine powder add Icing Sugar, mannitol, maltodextrin mixing after 300 mesh sieves; Add suitable quantity of water and make dry wet suitable soft material, become wet granular with 18 mu of sieve sieve series; Wet granular 60 ± 5 DEG C of dryings, then sifts out granulate with 16 mesh sieves, and middle product inspection, mensuration moisture control are within 5%; Add magnesium stearate, mix homogeneously, tabletting is made containing tablet; The weight ratio of described Chinese medicine powder and Icing Sugar, mannitol, maltodextrin and magnesium stearate is 100:40:100:50:2.6.
The Traditional Chinese medicine lozenge that the Chinese medicinal aqua for the treatment of oral ulcer embodiment 1 to 5 prepared and comparative example prepare is to occurring that the patient of oral ulcer uses, and the effect produced after number of users every example 50 people uses is as following table.
The service condition of table 1 embodiment 1 ~ 5 and comparative example
Note: the open sore part described in table occurs that discomfort refers to the scorching hot or twinge in open sore part place.
As known from Table 1, the Chinese medicinal aqua that the present invention prepares and license publication number are that compared with the Traditional Chinese medicine lozenge prepared of the invention of CN102872247A, healing time and cure rate are all significantly improved, and the open sore part not easily occurs discomfort.
Claims (9)
1. treat the Chinese medicinal aqua of oral ulcer for one kind, it is characterized in that, the Chinese medicinal aqua of described treatment cavity ulcer is made up by weight of following raw material: Fructus Momordicae 12 ~ 21 parts, Radix Sophorae Tonkinensis 12 ~ 18 parts, Radix Ilicis Asprellae 6 ~ 12 parts, Herba Menthae 9 ~ 15 parts, 6 ~ 13 parts, Radix Glycyrrhizae, Rhizoma Coptidis 8 ~ 18 parts, Radix Angelicae Sinensis 4 ~ 9 parts, Flos Lonicerae 5 ~ 11 parts and 200 ~ 600 parts, water.
2. a kind of Chinese medicinal aqua for the treatment of oral ulcer according to claim 1, it is characterized in that, the Chinese medicinal aqua of described treatment cavity ulcer is made up by weight of following raw material: Fructus Momordicae 12 ~ 21 parts, Radix Sophorae Tonkinensis 12 ~ 18 parts, Radix Ilicis Asprellae 6 ~ 12 parts, Herba Menthae 9 ~ 15 parts, 6 ~ 13 parts, Radix Glycyrrhizae, Rhizoma Coptidis 8 ~ 18 parts, Radix Angelicae Sinensis 4 ~ 9 parts, Flos Lonicerae 5 ~ 11 parts, 200 ~ 600 parts, water, Herba Houttuyniae 3 ~ 7 parts, Herba Patriniae 5 ~ 12 parts and Herba Asari 6 ~ 9 parts.
3. a kind of Chinese medicinal aqua for the treatment of oral ulcer according to claim 2, it is characterized in that, the Chinese medicinal aqua of described treatment cavity ulcer is made up by weight of following raw material: Fructus Momordicae 15 ~ 17 parts, Radix Sophorae Tonkinensis 14 ~ 16 parts, Radix Ilicis Asprellae 8 ~ 10 parts, Herba Menthae 11 ~ 13 parts, 7 ~ 11 parts, Radix Glycyrrhizae, Rhizoma Coptidis 12 ~ 14 parts, Radix Angelicae Sinensis 5 ~ 8 parts, Flos Lonicerae 6 ~ 9 parts, 300 ~ 500 parts, water, Herba Houttuyniae 4 ~ 6 parts, Herba Patriniae 7 ~ 10 parts and Herba Asari 6 ~ 8 parts.
4. a kind of Chinese medicinal aqua for the treatment of oral ulcer according to claim 2, it is characterized in that, the Chinese medicinal aqua of described treatment cavity ulcer is made up by weight of following raw material: Fructus Momordicae 16 parts, Radix Sophorae Tonkinensis 15 parts, Radix Ilicis Asprellae 9 parts, Herba Menthae 12 parts, 9 parts, Radix Glycyrrhizae, Rhizoma Coptidis 13 parts, Radix Angelicae Sinensis 6 parts, Flos Lonicerae 7 parts, 400 parts, water, Herba Houttuyniae 5 parts, Herba Patriniae 8 parts and Herba Asari 7 parts.
5. a kind of preparation method for the treatment of the Chinese medicinal aqua of oral ulcer according to claim 2, it is characterized in that, described preparation method comprises the steps:
Step one, cleans all medical materials with clear water;
Step 2, first Fructus Momordicae, Radix Sophorae Tonkinensis, Radix Ilicis Asprellae and Herba Menthae are carried out Mechanical Crushing, after fragmentation, carry out vacuum microwave drying, respectively above-mentioned Chinese crude drug is ground after drying, get Fructus Momordicae 12 ~ 21 parts, Radix Sophorae Tonkinensis 12 ~ 18 parts, Radix Ilicis Asprellae 6 ~ 12 parts and Herba Menthae 9 ~ 15 parts after strainer filtering respectively, be mixed to get A powder;
Step 3, this several raw material of Radix Glycyrrhizae, Rhizoma Coptidis, Radix Angelicae Sinensis, Flos Lonicerae, Herba Houttuyniae, Herba Patriniae and Herba Asari is carried out Mechanical Crushing respectively, after fragmentation, carry out lyophilization, respectively above-mentioned lyophilized products is ground after drying, distinguish extracting liquorice 6 ~ 13 parts, Rhizoma Coptidis 8 ~ 18 parts, Radix Angelicae Sinensis 4 ~ 9 parts, Flos Lonicerae 5 ~ 11 parts, Herba Houttuyniae 3 ~ 7 parts, Herba Patriniae 5 ~ 12 parts and Herba Asari 6 ~ 9 parts again after strainer filtering, be mixed to get B powder;
Step 4, by A powder and the mixing of B powder, adds 200 ~ 600 parts, water and soaks 2 hours rear filtered while hot of post-heating backflow, be the Chinese medicinal aqua for the treatment of oral ulcer after the cooling of gained filtrate.
6. a kind of preparation method for the treatment of the Chinese medicinal aqua of oral ulcer according to claim 5, is characterized in that, in described preparation method, step 2 and the filter screen particle diameter described in step 3 are 200 orders.
7. a kind of preparation method for the treatment of the Chinese medicinal aqua of oral ulcer according to claim 5, is characterized in that, in described preparation method, the baking temperature of the vacuum microwave drying described in step 2 is 45 DEG C, and vacuum is 100Pa, and microwave power is 800w.
8. a kind of preparation method for the treatment of the Chinese medicinal aqua of oral ulcer according to claim 5, is characterized in that, the cryodesiccated baking temperature in described preparation method described in step 3 is-15 DEG C, and sublimation drying is 4 hours.
9. a kind of preparation method for the treatment of the Chinese medicinal aqua of oral ulcer according to claim 5, is characterized in that, in described preparation method, the heating-up temperature of the reflux described in step 4 is 105 DEG C, and the time is 3 hours.
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| CN108815409A (en) * | 2018-08-09 | 2018-11-16 | 李妍 | A kind of preparation method of spray that treating canker sore |
| CN109846786A (en) * | 2019-03-25 | 2019-06-07 | 浙江省中医院 | A kind of Chinese medicine mouth wash and the preparation method and application thereof |
| CN116726104A (en) * | 2023-07-27 | 2023-09-12 | 南方医科大学中西医结合医院 | Traditional Chinese medicine composition for preventing and treating radioactive oral mucositis and preparation method thereof |
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2015
- 2015-04-15 CN CN201510175529.1A patent/CN104800369A/en active Pending
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN108815409A (en) * | 2018-08-09 | 2018-11-16 | 李妍 | A kind of preparation method of spray that treating canker sore |
| CN109846786A (en) * | 2019-03-25 | 2019-06-07 | 浙江省中医院 | A kind of Chinese medicine mouth wash and the preparation method and application thereof |
| CN109846786B (en) * | 2019-03-25 | 2022-03-25 | 浙江省中医院 | Traditional Chinese medicine mouth wash and preparation method and application thereof |
| CN116726104A (en) * | 2023-07-27 | 2023-09-12 | 南方医科大学中西医结合医院 | Traditional Chinese medicine composition for preventing and treating radioactive oral mucositis and preparation method thereof |
| CN116726104B (en) * | 2023-07-27 | 2024-06-11 | 南方医科大学中西医结合医院 | Traditional Chinese medicine composition for preventing and treating radioactive oral mucositis and preparation method thereof |
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