CN104740363A - Traditional Chinese medicine preparation for treating apoplectic hemiplegia and preparation method - Google Patents
Traditional Chinese medicine preparation for treating apoplectic hemiplegia and preparation method Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine preparation for treating apoplectic hemiplegia and a preparation method. The traditional Chinese medicine preparation is prepared from the following raw materials in parts by weight: 20-30 parts of pinellia ternate, 20-30 parts of rhizoma arisaematis, 30-45 parts of poria cocos, 10-15 parts of pericarpium citri reticulatae, 10-15 parts of fructus aurantii immaturus, 8-12 parts of polygala tenuifolia, 30-45 parts of caulis spatholobi, 8-12 parts of calculus bovis, 45-60 parts of roots of common peony, 45-60 parts of salviae miltiorrhizae, 50-65 parts of propolis and 30-45 parts of gastrodia elata. According to the traditional Chinese medicine preparation disclosed by the invention, an oral liquid prepared by virtue of a conventional preparation method of a modern preparation technology has the functions of benefiting qi for activating blood circulation and dispersing blood stasis and dredging collateral and is used for treating apoplectic hemiplegia symptoms such as hemiplegia, spastic hemiplegia, conscious disturbance hemiplegia and the like induced by stroke. The preparation method is free of toxic and side effects and remarkable in treatment effect, and fundamentally relieves pain of patients.
Description
Technical field
The invention belongs to the field of Chinese medicines, relate to a kind of hemiplegia, apoplexy, hemiplegia disease crowd take, especially a kind of Chinese medicine preparation and preparation method for the treatment of apoplectic hemiplegia.
Background technology
Hemiplegia is hemiplegia again, and referring to the dyskinesia of side upper and lower extremities, facial muscle and lingualis bottom, is the common sympton of acute cerebrovascular disease.Although slight hemiplegic patient still can be movable, walk, often upper limb flexing, lower limb stretch, and the lower limb of paralysis make a move and draw half circle, and this special walking posture, is called hemiplegic gait.Severe patient is often unable to leave the bed, and loses viability.According to the degree of hemiplegia, paresis, paresis and panplegia can be divided into.Paresis: show as muscular strength and weaken, muscular strength, at 4 ~ 5 grades, does not generally affect daily life, and imperfection paralysis is paresis weight comparatively, and scope is comparatively large, muscular strength 2 ~ 4 grades, panplegia: muscular strength 0 ~ 1 grade, paralyzed limbs is completely stiff.Apoplexy, names of disease of tcm, have exogenous wind and endogenous wind point, exogenous wind because of caused by being invaded by exogenous pathogen (ailment said due to cold or exposure), in treatise on Febrile Diseases name day apoplexy (also known as syndrome of decoction GUI ZHI (Ramulus cinnamomi)); Endogenous wind belongs to diseases caused by internal damage, also known as apoplexy, and apoplexy etc.Modern times generally claim apoplexy, refer to the syndrome similar to wind disease of diseases caused by internal damage more, how because QI and blood is inverse disorderly, the resistance of brain BI-syndrome involved the blood vessels or blood oozing from the body openings or subcuta neous tissue be caused by the brain.With unexpected dusk servant, hemiplegia, numb limbs and tense tendons, stiffness of the tongue in silence, crooked mouth and tongue, hemianesthesia etc. are the brain god disease of main manifestations.And there is onset urgency, change soon, as the disease of the feature of ailment said due to cold or exposure benefaction number change.
Current backroom boys both domestic and external has developed some treatment Western medicine of apoplectic hemiplegia and Chinese medicine as HUATUO ZAIZAO WAN, XIAOHUOLUO WAN, Sanfeng huoluo wan, ZHONGFENG HUICHUN WAN etc. through effort for many years, Western medicine is mainly for focus direct effect, but because this sick medication cycle is very long, easy generation drug resistance and toxic and side effects, and the price of this kind of medicine is often higher, patient medication cost is very high, and general family is all difficult to bear.This just needs more preferably Chinese medicine preparation, carrys out satisfied different patient demand.
Summary of the invention
The object of this invention is to provide that one has advantages of perfect compatibility, preparation is simple, cost is cheaper, toxic and side effects is little, nontoxic curative effect treats apoplectic hemiplegia Chinese medicine preparation and preparation method reliably.
For achieving the above object, the invention provides following technical scheme:
A kind of Chinese medicine preparation for the treatment of apoplectic hemiplegia of the present invention, each parts by weight of raw materials proportioning of this Chinese medicine preparation is: the Rhizoma Pinelliae 20 ~ 30 parts, Rhizoma Arisaematis 20 ~ 30 parts, 30 ~ 45 parts, Poria, Pericarpium Citri Reticulatae 10 ~ 15 parts, Fructus Aurantii Immaturus 10 ~ 15 parts, Radix Polygalae 8 ~ 12 parts, Caulis Spatholobi 30 ~ 45 parts, Calculus Bovis 8 ~ 12 parts, Radix Paeoniae Rubra 45 ~ 60 parts, Radix Salviae Miltiorrhizae 45 ~ 60 parts, propolis 50 ~ 65 parts, 30 ~ 45 parts, Rhizoma Gastrodiae.
A kind of Chinese medicine preparation for the treatment of apoplectic hemiplegia of the present invention, more preferably each parts by weight of raw materials proportioning is: the Rhizoma Pinelliae 22 ~ 28 parts, Rhizoma Arisaematis 22 ~ 28 parts, 30 ~ 40 parts, Poria, Pericarpium Citri Reticulatae 12 ~ 15 parts, Fructus Aurantii Immaturus 12 ~ 15 parts, Radix Polygalae 9 ~ 11 parts, Caulis Spatholobi 30 ~ 40 parts, Calculus Bovis 8 ~ 10 parts, Radix Paeoniae Rubra 45 ~ 50 parts, Radix Salviae Miltiorrhizae 45 ~ 50 parts, propolis 55 ~ 60 parts, 30 ~ 40 parts, Rhizoma Gastrodiae.
A kind of Chinese medicine preparation for the treatment of apoplectic hemiplegia of the present invention, best each parts by weight of raw materials proportioning is: the Rhizoma Pinelliae 25 parts, Rhizoma Arisaematis 25 parts, 30 parts, Poria, Pericarpium Citri Reticulatae 15 parts, Fructus Aurantii Immaturus 15 parts, Radix Polygalae 10 parts, Caulis Spatholobi 35 parts, Calculus Bovis 10 parts, Radix Paeoniae Rubra 45 parts, Radix Salviae Miltiorrhizae 50 parts, propolis 60 parts, 35 parts, Rhizoma Gastrodiae.
The medical material that the present invention uses has following characteristic:
The Rhizoma Pinelliae: the Rhizoma Pinelliae (formal name used at school: Pinellia ternata), has another name called ground literary composition, keeps field etc., belong to Arales.This product is that class is spherical, the slightly deflection had, superficial white or light yellow.Nature and flavor-Wen; Pungent; Return taste, lung meridian, cure mainly and effect: drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass.For abundant expectoration cough with asthma, phlegm retention vertigo and palpitation, dizziness due to wind-phlegm, syncope due to accumulation of phlegm is had a headache, vomiting regurgitation, and breast gastral cavity painful abdominal mass is vexed, globus hystericus; Raw with external treatment carbuncle sucutaneous nodule.
Rhizoma Arisaematis: be the dry tuber of aroid Rhizoma Arisaematis Arisaema erubescens (Wall.) Schott, Arisaema heterophyllum B1. Arisaemaheterophyllum Bl. or arisaema amurense Maxim Arisaema amurense Maxim..Another name: (Rhizoma Arisaematis, white Rhizoma Arisaematis, mountain maize, Serpentis Semen Maydis, mountain ear of maize).Nature and flavor-hardship, pungent, temperature, attending effectiveness: drying dampness to eliminate phlegm, expellings wind and relieving convulsion, effect of mass dissipating and swelling eliminating; For pertinacious phlegm cough, dizziness due to wind-phlegm, middle wind-phlegm is stopped up, mouth eye
tiltedly, hemiplegia, epilepsy, infantile convulsion, tetanus.
Poria: be the dry sclerotia of On Polyporaceae Poria Poria cocos (Schw.) Wolf.This product powder canescence.Irregular particle shape agglomerate and branched agglomerate colourless, meet chloral hydrate liquid and gradually dissolve.Nature and flavor-Gan, light, flat, GUIXIN, lung, spleen, kidney channel.Attending effectiveness: promoting diuresis to eliminate damp pathogen, spleen invigorating mind calming.For edema oliguria, phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, have loose bowels in loose stool, irritability, palpitation with fear insomnia.
Pericarpium Citri Reticulatae: be the dry mature skin of rutaceae orange Citrus reticulata Blanco and variety thereof.Medical material is divided into " Pericarpium Citri Reticulatae " and " Pericarpium citri reticuatae chachiensis ".Harvesting ripe fruit, strips peel, dries or cold drying.Nature and flavor-bitter in the mouth, pungent, warm in nature.Attending effectiveness: for distension and fullness in the abdomen, lack of appetite and vomiting, cough with copious phlegm.
Fructus Aurantii Immaturus: be the dry young fruit of rutaceae Citrus aurantium Linn. Citrus aurantium L. and variety or Fructus Citri sinensis Citrus sinensis Osbeck.5 ~ June collects the fruit from falling, and removing impurity, be two halves from middle part crosscut, dry or cold drying, smaller directly dries or cold drying.Nature and flavor-hardship, pungent, sour, be slightly cold.Attending effectiveness: stop in stagnant, feeling of fullness distending pain, heavy after dysentery, constipation, the stagnant vapour lock of expectorant, the thoracic obstruction, blocked-up chest, visceroptosis.
Radix Polygalae: (formal name used at school: Polygala tenuifolia Willd), You Ming Lush Rao, Ji Tseng-Lan etc.Year SHENGCAO this, main root is sturdy, phloem meat.Nature and flavor are bitter, pungent, warm.Return through GUIXIN, kidney, lung meridian.Attending effectiveness: the function of there is Fructus Alpiniae Oxyphyllae of calming the nerves, eliminate the phlegm, subsiding a swelling, the insomnia and dreamful sleep caused for disarmony between the heart and kidney, forgetful palpitation with fear, staring spells.
Caulis Spatholobi: be the another name of the various plants such as Schisandraceae, Sargentodoxaceae, Cuscutaceae, Papilionaceae, evergreen woody climber, without hair, shoot dirty-green, base portion Su Cunyou number piece triangular shape perula.The dark violet green of stem, has canescence hole skin, main root yellowish-brown, cross section mulberry.Nature and flavor-Wen; Bitter, sweet; Return Liver Channel, attending effectiveness: invigorate blood circulation, enrich blood, dredging collateral, for blood deficiency and yellow complexion, paralysis and numbness, rheumatic arthralgia.
Calculus Bovis: Calculus Bovis is the cholelithiasis of Chordata Mammalia bovid cattle drying.The title " jaundice due to fright or traumatic injury " produced in gallbladder or " egg yolk ", produce in bile duct title " pipe yellow ", the title produced in common hepatic duct " liver is yellow ".The complete person of Calculus Bovis is many in avette, light weight, and surface is golden yellow to yellowish-brown, fine and smooth and glossy.Chinese medicine thinks Calculus Bovis gas delicate fragrance, and mildly bitter flavor is then sweet, cool in nature.Can be used for antipyretic, removing toxic substances, arresting convulsion.The disease such as Zhi Gaore coma for oral administration, demented, infantile convulsion, tic, external is controlled laryngopharynx swelling and pain, aphtha carbuncle, is treated toxication.
Radix Paeoniae Rubra: be the dry root of ranunculaceae plant Radix Paeoniae Rubra or river Radix Paeoniae Rubra.Spring, Qiu Erji excavate, and removing rhizome, fibrous root and silt, dry.Hardship, is slightly cold.Return Liver Channel.There is clearing away heat and cooling blood, effect of blood circulation promoting and blood stasis dispelling.
Radix Salviae Miltiorrhizae: Radix Salviae Miltiorrhizae, Chinese medicine name.For the dry root welding technology of labiate Radix Salviae Miltiorrhizae Salvia miltiorrhiza Bge..Spring, Qiu Erji excavate, removing silt, dry.Whole nation most area has distribution.Bitter in the mouth, be slightly cold, GUIXIN, Liver Channel, have blood circulation promoting and blood stasis dispelling, inducing menstruation to relieve menalgia, and clear away heart-fire relieving restlessness, effect of removing heat from blood eliminating carbuncle.For obstruction of qi in the chest and cardialgia, gastral cavity abdomen hypochondriac pain, abdominal mass abdominal mass is gathered, pyretic arthralgia pain, dysphoria and insomnia, menoxenia, and dysmenorrhea amenorrhea, skin infection swells and ache.
Propolis: propolis is the resin that Apis gathers from plant spore or trunk, is mixed into palatine gland on it, a kind of colloidal solid thing with aromatic odor that the secretions of wax gland processes.Be the yellowish-brown of repairing secreted by Nidus Vespae or the stickums of pitchy such as Apidae animal apis cerana, can be used as medicine.It is cold in nature, bitter in the mouth, pungent, has skin moistening granulation promoting, effect of anti-inflammatory analgetic, can treat the diseases such as gastric ulcer, oral ulcer, burn and scald, skin splitting pain.
Rhizoma Gastrodiae: (formal name used at school: Gastrodia elata Bl.), having another name called rhizoma gastrodiae, solely shake sesame, from mother, close from grass, SHENCAO, yellow moccasin flower, Mokpo, RHIZONA GASTRODIAE, DINGFENGCAO, Bai Longpi etc., is the orchid family Gastrodia herbaceos perennial.Li Shizhen (1518-1593 A.D.) Compendium of Material Medica is specially set forth this, claims the name of " Rhizoma Gastrodiae ", for " descendant is called Rhizoma Gastrodiae.Root stock is plump, and without greenery, the capsule shape of falling ovum is oval, often with tuber or seminal propagation.Nature and flavor: sweet, flat, enter Liver Channel; The diseases such as treatment is had a dizzy spell, numb limbs and tense tendons, infantile convulsion.
A kind of Chinese medicine preparation and preparation method for the treatment of apoplectic hemiplegia of the present invention, the method comprises the steps:
1) each parts by weight of raw materials proportioning is taken: the Rhizoma Pinelliae 20 ~ 30 parts, Rhizoma Arisaematis 20 ~ 30 parts, 30 ~ 45 parts, Poria, Pericarpium Citri Reticulatae 10 ~ 15 parts, Fructus Aurantii Immaturus 10 ~ 15 parts, Radix Polygalae 8 ~ 12 parts, Caulis Spatholobi 30 ~ 45 parts, Calculus Bovis 8 ~ 12 parts, Radix Paeoniae Rubra 45 ~ 60 parts, Radix Salviae Miltiorrhizae 45 ~ 60 parts, propolis 50 ~ 65 parts, 30 ~ 45 parts, Rhizoma Gastrodiae;
2) above-mentioned all raw material cleanings are dried, be ground into granule, soak 1.5 hours, then decoct with water twice, add the water of crude drug 8 times amount for the first time, after intense fire is fried boiling, slow fire boiling 1-2 hour again, gets decocting liquid, filtration, and second time adds the water of crude drug 6 times amount, decoct 0.5-1.5 hour, get twice decocting liquid, filter, in heat-sealing bag, every bag of 200ml, high temperature sterilize, packs and get final product.
Usage and consumption: oral Chinese medicine preparation of the present invention, each 200ml, every day 2 times, half an hour after meal morning and evening 20 days is 1 course for the treatment of.
The present invention has selected Chinese crude drug as the principal agent for the treatment of apoplectic hemiplegia, starts with from strengthening the body resistance, nourshing blood and promoting blood circulation simultaneously, comprehensive determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, thus elimination paathogenic factor, the function of each system of comprehensive adjustment human body, strengthen human body stress and tolerance, therefore therapeutic effect is good.Namely Hemiplegic Patients majority is taken has positive effect in 1-2 week, and blood pressure recovers normal, and muscle power strengthens, and the mental status takes a turn for the better, muscular strength improves, numbness of hands and feet, and headache and dizzy phenomenon is eliminated, hemiplegia, facial hemiparalysis, limbs are weak, and say not smoothgoing stiff tongue, quadriplegia phenomenon is obviously improved; Continue to take, health recovers normal gradually, is fully recovered.
The effect of Chinese medicine composition of the present invention is set forth further below by way of clinical observation on the therapeutic effect.
1, physical data
Accept out-patient for medical treatment and have 120 examples altogether, 50 ~ 65 years old age, more than the course of disease 8 ~ December.
2, criterion of therapeutical effect
Formulate with reference to " Chinese medicine Clinical Researches of New Drugs guideline ".
Cure: neurological symptom and Signs disappear substantially, life is taken care of oneself completely;
Effective: neurological symptom and Signs major part disappear, and can not stand, living section is taken care of oneself;
Take a turn for the better: neurological symptom and Signs disappear, and support can be stood, and can't take care of oneself;
Invalid: without obviously changing after treatment, or after treatment, symptom and Signs increase the weight of.
3, therapeutic outcome, sees the following form:
Detailed description of the invention
Below in conjunction with the embodiment of the present invention, be clearly and completely described the technical scheme in the embodiment of the present invention, obviously, described embodiment is only the present invention's part embodiment, instead of whole embodiments.Based on the embodiment in the present invention, those of ordinary skill in the art, not making the every other embodiment obtained under creative work prerequisite, belong to the scope of protection of the invention.
Embodiment 1
1) each raw material weight proportioning is taken: Rhizoma Pinelliae 12g, Rhizoma Arisaematis 12g, Poria 15g, Pericarpium Citri Reticulatae 9g, Fructus Aurantii Immaturus 9g, Radix Polygalae 6g, Caulis Spatholobi 15g, Calculus Bovis 6g, Radix Paeoniae Rubra 30g, Radix Salviae Miltiorrhizae 30g, propolis 40g, Rhizoma Gastrodiae 15g;
2) above-mentioned all raw material cleanings are dried, be ground into granule, soak 1.5 hours, then decoct with water twice, add the water of crude drug 8 times amount for the first time, after intense fire is fried boiling, slow fire boiling 1-2 hour again, gets decocting liquid, filtration, and second time adds the water of crude drug 6 times amount, decoct 0.5-1.5 hour, get twice decocting liquid, filter, in heat-sealing bag, every bag of 200ml, high temperature sterilize, packs and get final product.
Embodiment 2
Each raw material weight proportioning: Rhizoma Pinelliae 12kg, Rhizoma Arisaematis 12kg, Poria 15kg, Pericarpium Citri Reticulatae 10kg, Fructus Aurantii Immaturus 10kg, Radix Polygalae 8kg, Caulis Spatholobi 15kg, Calculus Bovis 8kg, Radix Paeoniae Rubra 30kg, Radix Salviae Miltiorrhizae 30kg, propolis 40kg, Rhizoma Gastrodiae 18kg.
Manufacture method is the same with above-described embodiment 1.
Model case:
Case 1: Zhang Liang, man, 65 years old; Apoplectic hemiplegia, limbs are weak, numbness of hands and feet, substantially do not react, can't take care of oneself under knee, one lies stretched out on bed 5 years, in so for many years, and viewed from from county hospital to hospital of city several times, Chinese medicine, medical herbs, Western medicine, massage, washout Chinese herbal medicine, all continuous in use, effect is all not obvious.Opened two courses for the treatment of (40 days) Chinese medicine preparation of the present invention last year, muscular strength increases to some extent, not numb below knee.Current patient can leave the bed and slightly walk.
Case 2: Shen Jia, female, 55 years old; Say that apoplectic hemiplegia has had for many years according to family numbers of patients, his symptom facial hemiparalysis, numb limbs and tense tendons, headache and dizzy, Chinese medicine and western medicine was all used, and was exactly ineffective.Eaten the Chinese medicine preparation of the present invention of two courses for the treatment of (40 days) afterwards, and be clearly better, mouth eye recovers normal direction substantially, headache and dizzy phenomenon disappears, and can have a meal very smoothly, extremity there has also been consciousness, can loose, after continuing again to have taken a course for the treatment of, fully recover at present.
Case 3: Zhang Min, female, 50 years old; Readme starts to find that blood pressure raises for 2013, and usually often feel dizziness and headache, tinnitus flushed complexion, lassitude loin and legs, suddenly facial hemiparalysis occurs, slobbering, dysphasia, left hemiplegia, and Tongue Deviation is trembleed.[tcm diagnosis] is pneumatic the levying of hyperactivity of YANG due to deficiency of YIN, yellowish fur, is the time of accumulation of phlegm-heat in the interior.Take (20 days) Chinese medicine preparation of the present invention afterwards, good, the left half body muscular strength of mental attitude increases, does not occur waist and leg ache, and the state of an illness takes an evident turn for the better, and continues again to have taken a course for the treatment of, can do simple housework at present.
Claims (5)
1. treat the Chinese medicine preparation of apoplectic hemiplegia for one kind; it is characterized in that, each parts by weight of raw materials proportioning of this Chinese medicine preparation is: the Rhizoma Pinelliae 20 ~ 30 parts, Rhizoma Arisaematis 20 ~ 30 parts, 30 ~ 45 parts, Poria, Pericarpium Citri Reticulatae 10 ~ 15 parts, Fructus Aurantii Immaturus 10 ~ 15 parts, Radix Polygalae 8 ~ 12 parts, Caulis Spatholobi 30 ~ 45 parts, Calculus Bovis 8 ~ 12 parts, Radix Paeoniae Rubra 45 ~ 60 parts, Radix Salviae Miltiorrhizae 45 ~ 60 parts, propolis 50 ~ 65 parts, 30 ~ 45 parts, Rhizoma Gastrodiae.
2. the Chinese medicine preparation for the treatment of apoplectic hemiplegia according to claim 1, is characterized in that the more excellent weight of each raw material of this Chinese medicine preparation is: the Rhizoma Pinelliae 22 ~ 28 parts, Rhizoma Arisaematis 22 ~ 28 parts, 30 ~ 40 parts, Poria, Pericarpium Citri Reticulatae 12 ~ 15 parts, Fructus Aurantii Immaturus 12 ~ 15 parts, Radix Polygalae 9 ~ 11 parts, Caulis Spatholobi 30 ~ 40 parts, Calculus Bovis 8 ~ 10 parts, Radix Paeoniae Rubra 45 ~ 50 parts, Radix Salviae Miltiorrhizae 45 ~ 50 parts, propolis 55 ~ 60 parts, 30 ~ 40 parts, Rhizoma Gastrodiae.
3. the Chinese medicine preparation for the treatment of apoplectic hemiplegia according to claim 1, is characterized in that this Chinese medicine preparation each raw material optimum weight part proportioning is: the Rhizoma Pinelliae 25 parts, Rhizoma Arisaematis 25 parts, 30 parts, Poria, Pericarpium Citri Reticulatae 15 parts, Fructus Aurantii Immaturus 15 parts, Radix Polygalae 10 parts, Caulis Spatholobi 35 parts, Calculus Bovis 10 parts, Radix Paeoniae Rubra 45 parts, Radix Salviae Miltiorrhizae 50 parts, propolis 60 parts, 35 parts, Rhizoma Gastrodiae.
4. the Chinese medicine preparation of the treatment apoplectic hemiplegia according to any one of claims 1 to 3, is characterized in that described Chinese medicine preparation is prepared as oral liquid.
5. the preparation method of the Chinese medicine preparation for the treatment of apoplectic hemiplegia according to claim 1, is characterized in that the method comprises the steps:
1) each parts by weight of raw materials proportioning is taken: the Rhizoma Pinelliae 20 ~ 30 parts, Rhizoma Arisaematis 20 ~ 30 parts, 30 ~ 45 parts, Poria, Pericarpium Citri Reticulatae 10 ~ 15 parts, Fructus Aurantii Immaturus 10 ~ 15 parts, Radix Polygalae 8 ~ 12 parts, Caulis Spatholobi 30 ~ 45 parts, Calculus Bovis 8 ~ 12 parts, Radix Paeoniae Rubra 45 ~ 60 parts, Radix Salviae Miltiorrhizae 45 ~ 60 parts, propolis 50 ~ 65 parts, 30 ~ 45 parts, Rhizoma Gastrodiae;
2) above-mentioned all raw material cleanings are dried, be ground into granule, soak 1.5 hours, then decoct with water twice, add the water of crude drug 8 times amount for the first time, after intense fire is fried boiling, slow fire boiling 1-2 hour again, gets decocting liquid, filtration, and second time adds the water of crude drug 6 times amount, decoct 0.5-1.5 hour, get twice decocting liquid, filter, in heat-sealing bag, every bag of 200ml, high temperature sterilize, packs and get final product.
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