CN104721444B - A kind of Chinese medicine composition and preparation method thereof for treating burn - Google Patents
A kind of Chinese medicine composition and preparation method thereof for treating burn Download PDFInfo
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Abstract
The invention discloses a kind of Chinese medicine composition and preparation method thereof for treating burn, the Chinese medicine composition includes the raw material of following parts by weight：First dose：8-12 parts of 15-22 parts of the coptis, 15-22 parts of charred RADIX SANGUISORBAE, 6-9 parts of akebi, 5-8 parts of dragon's blood, 5-8 parts of Asian puccoon, 15-22 parts of duck bone, 8-13 parts of chrysanthemum, 8-13 parts of dandelion, 8-10 parts of honey, 8-10 parts of lime and vitamin D；Second dose：12-18 parts of 18-22 parts of duck oil, 5-10 parts of pearl powder, 8-12 parts of gypsum, 20-25 parts of aloe, 15-22 parts of egg white, 8-10 parts of beeswax, 8-12 parts of vitamin A and vitamin E.Root first dose of bactericidal, anti-inflammatory analgesic, removing necrosis, promoting granulation of the present invention, second dose promoting blood circulation and removing blood stasis, eliminating dampness and astringing sores, moisturizing support flesh, to achieve the purpose that treating both manifestation and root cause of disease.The preparation method of the present invention improves the recovery rate of active constituents of medicine, has promotional value.
Description
Technical field
The present invention relates to field of Chinese medicinal composition, and in particular to a kind of Chinese medicine composition that treating burn and its preparation side
Method.
Background technology
Burn refers generally to heating power, including hydrothermal solution (water, soup, oil etc.), steam, high-temperature gas, flame, red-hot metal liquid or
Histologic lesion caused by solid (such as molten steel, steel ingot) etc., refers mainly to skin and/or mucous membrane, and severe patient can also injure subcutaneously
Or/and sub-mucosal tissues, such as muscle, bone, joint even internal organ.Its severity is divided into slight, moderate and severe.With the modern times
The variation of industrial expansion and social rhythm, various burns are growing day by day, and burn becomes the clinical common serious harm mankind
The injury of health, can also cause certain psychic trauma to patient.
Modern medical therapy burn has integrative medicine therapy.Tcm therapy is generally simple Chinese medicinal ointment, smears wound, general
All over that can accomplish to prevent from infecting, promote Wound healing, but there is also some problems：A kind of paste is smeared during entire treatment, no
It can be shot the arrow at the target according to the healing state of wound, wound leaves different degrees of scar after curing.Western medicine therapy is generally slight
Antibiotics lotion closed treating, severe surgical operation therapy are smeared, but there is also some problems：Closed treating is easy infectious wound
Mouthful, cause surface of a wound ulcer；Operative treatment cannot relieve pain in time, and self skin grafting increases the pain of patient, surgery cost is high,
Treatment time length etc..
Invention content
It is excellent it is an object of the invention to solve at least the above and/or defect, and provide at least to will be described later
Point.
It is a still further object of the present invention to provide a kind of Chinese medicine compositions for treating burn, can be according to the reparation journey of wound
Degree, treatment at different stages, first dose of drug focus on the function of bactericidal, anti-inflammatory analgesic, removing necrosis, promoting granulation, and second dose of drug focuses on work
Blood stagnation resolvation, eliminating dampness and astringing sores, moisturizing support flesh function, to achieve the purpose that treating both manifestation and root cause of disease.
It is a still further object of the present invention to provide a kind of preparation methods of Chinese medicine composition that treating burn, by traditional Chinese medicine
Classification processes, and suspension, which is made, in first dose of Chinese medicine sprays wound, and paste application wound is made in second dose of Chinese medicine, of the invention
Preparation method is simple, equipment is easy to operate, can improve the recovery rate of active constituents of medicine and the utilization rate of the energy, has promotion price
Value.
In order to realize these purposes and other advantages according to the present invention, a kind of Chinese traditional medicine composition for treating burn is provided
Object, the Chinese medicine composition include the raw material of following parts by weight：
First dose：15-22 parts of the coptis, 15-22 parts of charred RADIX SANGUISORBAE, 6-9 parts of akebi, 5-8 parts of dragon's blood, 5-8 parts of Asian puccoon, duck bone
15-22 parts, 8-13 parts of chrysanthemum, 8-13 parts of dandelion, 8-10 parts of honey, 8-12 parts of 8-10 parts of lime and vitamin D；
Second dose：18-22 parts of duck oil, 5-10 parts of pearl powder, 8-12 parts of gypsum, 20-25 parts of aloe, 15-22 parts of egg white,
12-18 parts of 8-10 parts of beeswax, 8-12 parts of vitamin A and vitamin E.
Preferably, the Chinese medicine composition of the treatment burn, the Chinese medicine composition includes the original of following parts by weight
Material：
First dose：18 parts of the coptis, 18 parts of charred RADIX SANGUISORBAE, 7 parts of akebi, 7 parts of dragon's blood, 7 parts of Asian puccoon, 18 parts of duck bone, 10 parts of chrysanthemum,
10 parts of 10 parts of dandelion, 9 parts of honey, 9 parts of lime and vitamin D；
Second dose：21 parts of duck oil, 7 parts of pearl powder, 10 parts of gypsum, 22 parts of aloe, 18 parts of egg white, 9 parts of beeswax, dimension life
Plain A10 parts and 15 parts of vitamin E.
The purpose of the present invention can also be realized further by the preparation method of the Chinese medicine composition for the treatment of burn, wherein
First dose of preparation includes the following steps：
Step 1: the dragon's blood of above-mentioned parts by weight, chrysanthemum, dandelion and lime are dried, it is crushed to 140-200 mesh, is mixed
Fine powder material is obtained after closing uniformly；
Step 2: being freeze-dried the duck bone of above-mentioned parts by weight, it is crushed to 60-80 mesh, mixes the Huang of above-mentioned parts by weight
Company, charred RADIX SANGUISORBAE, akebi and Asian puccoon are placed in the 2-3 times of clear water measured and impregnate 1-2h, and Chinese medicine, mistake are exposed in high heat decoction to the water surface
Filter obtains the dregs of a decoction and the first filtrate, the 6-8 times of ethanol water for measuring 40%-55% of addition in the dregs of a decoction, refluxing extraction 2-3 times,
Merge extracting solution, the second filtrate is obtained by filtration, merges the first filtrate and the second filtrate uses ethyl alcohol by large pore resin absorption column
Elution 2-3 times collects eluent, ethyl alcohol is recovered under reduced pressure, obtains liquid material；
Step 3: the fine powder material that step 1 obtains and the liquid material that step 2 obtains are mixed, honey is added, stirs 8-
After 10h, first dose of suspension is made.
Preferably, the preparation method of the Chinese medicine composition of the treatment burn, second dose of preparation includes following step
Suddenly：
Step 4: the duck oil of above-mentioned weight fraction is melted, the beeswax, pearl powder and gypsum of above-mentioned parts by weight is added,
After stirring 8-10h, it is cooled to room temperature, for use；
Step 5: the vitamin A of above-mentioned parts by weight and vitamin E are dissolved in the egg white of above-mentioned parts by weight,
After stirring 3-5h, for use；
Step 6: the aloe of above-mentioned parts by weight is cut into segment, using CO2Supercritical extract obtains aloe extract；
Step 7: by Step 4: Step 5: the product that step 6 obtains stirs 8-10h at normal temperatures, 2-3 times of addition is measured
Water, after standing, centrifuge 5-8min under the rotating speed of 2000r/min, be placed in liquid separation in separatory funnel and obtain oil phase, be made second
The medicinal extract of agent.
Preferably, the preparation method of the Chinese medicine composition of the treatment burn, the preparation method of the honey are：Take spring
Honey in the new honeycomb of acquisition, is tempered with slow boiling, filters off foam, the fresh mint leaf and Bulbus Lilii leaf smashed to pieces is added after cooling,
Stir 2~3h, sieve with 100 mesh sieve, be added vitamin D, stirring 2~3h to get.
Preferably, the preparation method of the Chinese medicine composition of the treatment burn, the preparation method of the beeswax are：By the spring
It is placed in steamer after the new honeycomb removal honey of season acquisition, 2-3h is steamed with the alcoholic solution of 75-80% volume fractions, controls temperature
It it is 60-70 DEG C, until beeswax is melted to liquid, fresh dried peppermint leaf, which is layered on layer 2-3 on funnel, substitutes filter paper, and filtering will obtain
Filtrate cool down to get.
Preferably, the preparation method of the Chinese medicine composition of the described treatment burn, in step 2, the elution is to instigate
The ethyl alcohol measured with 1-2 times, flow velocity are to measure for 1-2 times per hour.
Preferably, the preparation method of the Chinese medicine composition of the treatment burn, the CO2The behaviour of supercritical extract
It is as condition：30~35MPa, 40~45 DEG C, 2~3h.
Preferably, the preparation method of the Chinese medicine composition of the treatment burn, the duck oil are the fat refining of duck
The 2-3 times of water measured is added in the oil of system, after standing, centrifuges 5-8min under the rotating speed of 2000r/min, is placed in separatory funnel liquid separation
Obtained oil phase is to get duck oil.
The present invention includes at least following advantageous effect：
The first, in first dose, the coptis is the medicine of bitter cold, heat-clearing and damp-drying drug, purging intense heat and detonicating, charred RADIX SANGUISORBAE cooling blood and removing stasis, akebi profit
Treating stranguria, dragon's blood removing blood stasis and hemostasis, Asian puccoon removing pattogenic heat from the blood and toxic material from the body are urinated, the cool property of duck bone is relieved inflammation or internal heat, and chrysanthemum is clearing heat and detoxicating, and dandelion dispersing swelling and dissipating binds are taken
It is used with honey, lime, complements each other, interacts, the wound at burn treating initial stage is heated with cold, relieve the pain fast, myogenic speed；
The second, in second dose, the scattered fire of duck oil is subsided a swelling, and pearl powder is rich in calcareous, solution acne treatment poison, promotion tissue growth, aloe
Detoxifying and relieving itching, repairs skin, egg white heat-clearing skin care, and collocation gypsum, beeswax use, complement each other, interact, control burn
Wound swelling and pain relieving, the skin moistening and itch stopping for treating the later stage, promote the growth of dermal fibroblasts；
Third, the present invention are according to theory of traditional Chinese medical science, and treatment burn, first dose of drug are suitable for burning at the beginning of wound in two stages
Phase removes necrosis and promote granulation to antibacterial skin anti-inflammatory, and after first dose of drug, inflammation is reduced, damp and hot to be eased, and is begun to use
Second dose of medicine, second dose of drug focus on the convergence open sore part, moisturizing, while continuing with cold heating, by this stage skin healing,
Scar desalination is not itched bitterly, to achieve the purpose that treating both manifestation and root cause of disease；
In four, the first doses of preparation, according to pharmacological property difference, siccative is worn into fine powder, column elution is crossed after root material is decocted,
Fully dissolving active ingredient obtains the concentration essence of Chinese medicine liquid, and suspension is made in collocation honey and dispersant, to wound after shaking up
Mouth is sprayed, and big, quick good effect quick into human body cell is accumulated by powder, huge caused by preventing wound initial stage from smearing
Big pain；
In the preparation of five, the second doses of medicines, compatibility beeswax, pearl powder and gypsum after duck oil is melted mix chicken after cooling
Egg white avoids that egg white is allowed to inactivate, and the aloe stoste of supercritical extract is added, and improves active ingredient purity and content, collocation
Paste is made, facilitates and smears wound, avoids itching moisturizing, it is easy to use；
6th, spring plant petal is just opened, and nectar source is wide, and the honey of acquisition is new honey, to streptococcus, staphylococcus, diphtheria
Equal gram positive bacterias have stronger inhibiting effect, and the fresh mint leaf and Bulbus Lilii leaf smashed to pieces just is added after system, neutralizes the heat of honey
Property, and increase the aromaticity of drug, it allows the wound of patient to feel pure and fresh refrigerant, vitamin D is added, promote skin to calcareous suction
It receives, supplements the nutrients, reduce exudation, mitigate pain, promote wound healing, prevent from infecting；
7th, beeswax is steamed under alcoholic solution atmosphere, removes impurity, while dissolving beeswax, mix alcoholic content,
It carries out disinfection to wound, kills virus to the harmful substance in liquid, the beeswax just made is rich in acids, free-fat carotenoid etc.
Be conducive to the convergent component of wound, after peppermint is filtered, beeswax adulterates peppermint fragrance, neutralizes hot, allows the wound sense of patient
To refrigerant, conditioning skin.
Part is illustrated to embody by further advantage, target and the feature of the present invention by following, and part will also be by this
The research and practice of invention and be understood by the person skilled in the art.
Specific implementation mode
With reference to embodiment, the present invention is described in further detail, to enable those skilled in the art with reference to specification
Word can be implemented according to this.
<Embodiment 1>
A kind of Chinese medicine composition for treating burn, the Chinese medicine composition include the raw material of following parts by weight：
First dose：15 parts of the coptis, 15 parts of charred RADIX SANGUISORBAE, 6 parts of akebi, 5 parts of dragon's blood, 5 parts of Asian puccoon, 15 parts of duck bone, 8 parts of chrysanthemum,
8 parts of 8 parts of dandelion, 8 parts of honey, 8 parts of lime and vitamin D；
Second dose：18 parts of duck oil, 5 parts of pearl powder, 8 parts of gypsum, 20 parts of aloe, 15 parts of egg white, 8 parts of beeswax, vitamin
A8 parts and 12 parts of vitamin E.
Wherein, in first dose, the preparation method of the honey is：The honey in the new honeycomb of spring acquisition is taken, is tempered with slow boiling,
Foam is filtered off, the fresh mint leaf and Bulbus Lilii leaf smashed to pieces are added after cooling, 2h is stirred, sieves with 100 mesh sieve, vitamin D, stirring is added
2h to get.
In second dose, the preparation method of the beeswax is：It will be placed in steamer after the new honeycomb removal honey of spring acquisition, with 75
The alcoholic solution of volume fraction steams 2h, and controlled at 60 DEG C, until beeswax is melted to liquid, fresh dried peppermint leaf is layered on leakage
Struggle against it is upper 2 layers replacement filter paper, filtering, by obtained filtrate cool down to get.
In second dose, the duck oil is the oil of the rendering of fats of duck, and the water of 2 times of amounts are added, after standing, in 2000r/
5min is centrifuged under the rotating speed of min, is placed in oil phase that separatory funnel liquid separation obtains to get duck oil.
A kind of preparation method of Chinese medicine composition that treating burn, wherein first dose of preparation includes the following steps：
Step 1: the dragon's blood of above-mentioned parts by weight, chrysanthemum, dandelion and lime are dried, 140 mesh are crushed to, mixing is equal
Fine powder material is obtained after even；
Step 2: being freeze-dried the duck bone of above-mentioned parts by weight, be crushed to 60 mesh, mix above-mentioned parts by weight the coptis,
Charred RADIX SANGUISORBAE, akebi and Asian puccoon, are placed in times clear water of amount and impregnate 1h, and high heat decoction to the water surface exposes Chinese medicine, medicine is obtained by filtration
Slag and the first filtrate, are added the ethanol water of 6 times of amounts 40% in the dregs of a decoction, and refluxing extraction 2 times merges extracting solution, filters
To the second filtrate, merge the first filtrate and the second filtrate, by large pore resin absorption column, with ethanol elution 2 times, elution every time makes
The ethyl alcohol measured with 1 times, flow velocity are measured for 1 times per hour, collect eluent, ethyl alcohol is recovered under reduced pressure, obtains liquid material；
Step 3: the fine powder material that step 1 obtains and the liquid material that step 2 obtains are mixed, honey is added, stirs 8h
Afterwards, first dose of suspension is made.
Second dose of preparation includes the following steps：
Step 4: the duck oil of above-mentioned weight fraction is melted, the beeswax, pearl powder and gypsum of above-mentioned parts by weight is added,
After stirring 8h, it is cooled to room temperature, for use；
Step 5: the vitamin A of above-mentioned parts by weight and vitamin E are dissolved in the egg white of above-mentioned parts by weight,
After stirring 3h, for use；
Step 6: the aloe of above-mentioned parts by weight is cut into segment, using CO2Supercritical extract, operating condition are：
30MPa, 40 DEG C, 2h obtains aloe extract；
Step 7: by Step 4: Step 5: the product that step 6 obtains stirs 8h at normal temperatures, the water of 2 times of amounts are added,
After standing, 5min is centrifuged under the rotating speed of 2000r/min, liquid separation in separatory funnel is placed in and obtains oil phase, second dose of leaching is made
Cream.
<Embodiment 2>
A kind of Chinese medicine composition for treating burn, the Chinese medicine composition include the raw material of following parts by weight：
First dose：22 parts of the coptis, 22 parts of charred RADIX SANGUISORBAE, 9 parts of akebi, 8 parts of dragon's blood, 8 parts of Asian puccoon, 22 parts of duck bone, 13 parts of chrysanthemum,
12 parts of 13 parts of dandelion, 10 parts of honey, 10 parts of lime and vitamin D；
Second dose：22 parts of duck oil, 5-10 parts of pearl powder, 8-12 parts of gypsum, 20-25 parts of aloe, 15-22 parts of egg white, bee
12-18 parts of 8-10 parts of wax, 8-12 parts of vitamin A and vitamin E.
Wherein, in first dose, the preparation method of the honey is：The honey in the new honeycomb of spring acquisition is taken, is tempered with slow boiling,
Foam is filtered off, the fresh mint leaf and Bulbus Lilii leaf smashed to pieces are added after cooling, 3h is stirred, sieves with 100 mesh sieve, vitamin D, stirring is added
3h to get.
In second dose, the preparation method of the beeswax is：It will be placed in steamer after the new honeycomb removal honey of spring acquisition, used
The alcoholic solution of 80% volume fraction steams 3h, and controlled at 70 DEG C, until beeswax is melted to liquid, fresh dried peppermint leaf is spread
On funnel 3 layers replacement filter paper, filtering, by obtained filtrate cool down to get.
In second dose, the duck oil is the oil of the rendering of fats of duck, and the water of 3 times of amounts are added, after standing, in 2000r/
8min is centrifuged under the rotating speed of min, is placed in oil phase that separatory funnel liquid separation obtains to get duck oil.
A kind of preparation method of Chinese medicine composition that treating burn, wherein first dose of preparation includes the following steps：
Step 1: the dragon's blood of above-mentioned parts by weight, chrysanthemum, dandelion and lime are dried, 200 mesh are crushed to, mixing is equal
Fine powder material is obtained after even；
Step 2: being freeze-dried the duck bone of above-mentioned parts by weight, be crushed to 80 mesh, mix above-mentioned parts by weight the coptis,
Charred RADIX SANGUISORBAE, akebi and Asian puccoon are placed in the clear water of 3 times of amounts and impregnate 2h, and Chinese medicine is exposed in high heat decoction to the water surface, and medicine is obtained by filtration
Slag and the first filtrate, are added the ethanol water of 8 times of amounts 55% in the dregs of a decoction, and refluxing extraction 3 times merges extracting solution, filters
To the second filtrate, merge the first filtrate and the second filtrate, by large pore resin absorption column, with ethanol elution 3 times, elutes every time
When, the ethyl alcohol measured using 2 times, flow velocity is measured for 2 times per hour, collects eluent, ethyl alcohol is recovered under reduced pressure, obtains liquid material；
Step 3: the fine powder material that step 1 obtains and the liquid material that step 2 obtains are mixed, honey is added, stirs 8-
After 10h, first dose of suspension is made.
Second dose of preparation includes the following steps：
Step 4: the duck oil of above-mentioned weight fraction is melted, the beeswax, pearl powder and gypsum of above-mentioned parts by weight is added,
After stirring 10h, it is cooled to room temperature, for use；
Step 5: the vitamin A of above-mentioned parts by weight and vitamin E are dissolved in the egg white of above-mentioned parts by weight,
After stirring 5h, for use；
Step 6: the aloe of above-mentioned parts by weight is cut into segment, using CO2Supercritical extract, operating condition are：
35MPa, 45 DEG C, 3h obtains aloe extract；
Step 7: by Step 4: Step 5: the product that step 6 obtains stirs 10h at normal temperatures, the water of 3 times of amounts are added,
After standing, 8min is centrifuged under the rotating speed of 2000r/min, liquid separation in separatory funnel is placed in and obtains oil phase, second dose of leaching is made
Cream.
<Embodiment 3>
A kind of Chinese medicine composition for treating burn, the Chinese medicine composition include the raw material of following parts by weight：
First dose：18 parts of the coptis, 18 parts of charred RADIX SANGUISORBAE, 7 parts of akebi, 7 parts of dragon's blood, 7 parts of Asian puccoon, 18 parts of duck bone, 10 parts of chrysanthemum,
10 parts of 10 parts of dandelion, 9 parts of honey, 9 parts of lime and vitamin D；
Second dose：21 parts of duck oil, 7 parts of pearl powder, 10 parts of gypsum, 22 parts of aloe, 18 parts of egg white, 9 parts of beeswax, dimension life
15 parts of 10 parts of plain A and vitamin E.
In first dose, the preparation method of the honey is：The honey in the new honeycomb of spring acquisition is taken, is tempered with slow boiling, is filtered off
The fresh mint leaf and Bulbus Lilii leaf smashed to pieces is added in foam after cooling, stir 2.5h, crosses 100 mesh sieve, and vitamin D, stirring is added
2.5h to get.
In second dose, the preparation method of the beeswax is：It will be placed in steamer after the new honeycomb removal honey of spring acquisition, used
The alcoholic solution of 78% volume fraction steams 2.5h, controlled at 65 DEG C, until beeswax is melted to liquid, by fresh dried peppermint leaf
Be layered on funnel 2 layers of replacement filter paper, filtering, by obtained filtrate cool down to get.
In second dose, the duck oil is the oil of the rendering of fats of duck, and the water of 2.5 times of amounts are added, after standing, in 2000r/
7min is centrifuged under the rotating speed of min, is placed in oil phase that separatory funnel liquid separation obtains to get duck oil.
A kind of preparation method of Chinese medicine composition that treating burn, wherein first dose of preparation includes the following steps：
Step 1: the dragon's blood of above-mentioned parts by weight, chrysanthemum, dandelion and lime are dried, 180 mesh are crushed to, mixing is equal
Fine powder material is obtained after even；
Step 2: being freeze-dried the duck bone of above-mentioned parts by weight, be crushed to 70 mesh, mix above-mentioned parts by weight the coptis,
Charred RADIX SANGUISORBAE, akebi and Asian puccoon are placed in the clear water of 2.5 times of amounts and impregnate 1.5h, and Chinese medicine is exposed in high heat decoction to the water surface, filters
To the dregs of a decoction and the first filtrate, the ethanol water of 7 times of amounts 48% is added in the dregs of a decoction, refluxing extraction 3 times merges extracting solution, mistake
Filter obtains the second filtrate, merges the first filtrate and the second filtrate, by large pore resin absorption column, with ethanol elution 3 times, washes every time
The de- ethyl alcohol using 1.5 times of amounts, flow velocity are measured for 1.5 times per hour, collect eluent, ethyl alcohol is recovered under reduced pressure, obtains liquid material；
Step 3: the fine powder material that step 1 obtains and the liquid material that step 2 obtains are mixed, honey is added, stirs 9h
Afterwards, first dose of suspension is made.
Second dose of preparation includes the following steps：
Step 4: the duck oil of above-mentioned weight fraction is melted, the beeswax, pearl powder and gypsum of above-mentioned parts by weight is added,
After stirring 9h, it is cooled to room temperature, for use；
Step 5: the vitamin A of above-mentioned parts by weight and vitamin E are dissolved in the egg white of above-mentioned parts by weight,
After stirring 4h, for use；
Step 6: the aloe of above-mentioned parts by weight is cut into segment, using CO2Supercritical extract, operating condition are：
32MPa, 42 DEG C, 2.5h obtains aloe extract；
Step 7: 2.5 times of amounts Step 4: Step 5: the product that step 6 obtains stirs 9h at normal temperatures, will be added
Water after standing, centrifuges 7min under the rotating speed of 2000r/min, is placed in liquid separation in separatory funnel and obtains oil phase, is made second dose
Medicinal extract.
<Comparative example 1>
Burn patient therapeutic test is reported：
One, clinical observation：
1, burn patient 60 is selected, wherein mild burn, moderate burn and each 20 people of severe burn are equally divided into 6
Group：
Control group 1：10 people of mild burn, jingwanhong soft plaster, every 6 hours coatings are primary；
Control group 2：10 people of moderate burn, jingwanhong soft plaster, every 4 hours coatings are primary；
Control group 3：10 people of severe burn, jingwanhong soft plaster, every 2 hours coatings are primary；
Treatment group 1：10 people of mild burn, obtain first dose and second dose of the embodiment of the present invention 1, every 6 before Wound healing
Sprinkling suspension is primary after hour shakes up, and wound starts to heal every 6 hours, and to smear paste primary；
Treatment group 2：10 people of moderate burn, obtain first dose and second dose of the embodiment of the present invention 2, every 4 before Wound healing
Sprinkling suspension is primary after hour shakes up, and wound starts to heal every 4 hours, and to smear paste primary；
Treatment group 3：10 people of severe burn, obtain first dose and second dose of the embodiment of the present invention 3, every 2 before Wound healing
Sprinkling suspension is primary after hour shakes up, and wound starts to heal every 2 hours, and to smear paste primary.
Two, efficacy assessment standard：
Wound healing, scar is shallow, not itch, and pigment deposition is few, without thick scab.
Three, treatment results：
Table 1：Control group and treatment group's result
| Control group 1 | Treatment group 1 | Control group 2 | Treatment group 2 | Control group 3 | Treatment group 3 | |
| Example time | 10 | 10 | 10 | 10 | 10 | 10 |
| Healing number | 10 | 10 | 8 | 10 | 5 | 8 |
| Treatment cycle | 7 | 5 | 13 | 9 | 26 | 19 |
As can be seen from the above table, treatment group's drug effect is fairly obvious compared to control group, wherein in mild burn, control
The cure rate of group 1 and treatment group 1 is all 100%, but 1 treatment cycle for the treatment of group is shorter；In moderate burn, treatment group 2 cures
Rate is 100%, and control group 2 is 80%, and 2 treatment cycle for the treatment of group is short, quick；In severe burn, treatment group 3 and control
The cure rate of group 3 is respectively 80% and 50%, and 3 treatment cycle for the treatment of group is than 3 few one week of control group, quick, curative effect
It is good.
<Comparative example 2>
Case 1：Gold so-and-so, female 35 years old, scalds both legs by one pot of boiling hot thin rice gruel, gives the suspension that the present embodiment 3 obtains
After agent sprays 7 days, wound is alleviated, and then gives paste application that the present embodiment 3 obtains after 4 days, cures.
Case 2：Liu, man 20 years old, when laboratory operation chemical experiment, corrode arm by the concentrated sulfuric acid, give this implementation
After suspending agent that example 3 obtains sprays 12 days, wound is alleviated, and then gives paste application that the present embodiment 3 obtains after 10 days,
It cures.
Case 3：It is remaining so-and-so, female, 40 years old, be in burn coal when burnt accidentally by open fire, give the suspension that the present embodiment 3 obtains
After agent sprays 20 days, wound is alleviated, and then gives paste application that the present embodiment 3 obtains after 8 days, cures.
Although the embodiments of the present invention have been disclosed as above, but its is not only in the description and the implementation listed
With it can be fully applied to various fields suitable for the present invention, for those skilled in the art, can be easily
Realize other modification, therefore without departing from the general concept defined in the claims and the equivalent scope, the present invention is simultaneously unlimited
In specific details and embodiment shown and described herein.
Claims (9)
1. a kind of external medicine composition for treating burn, the Chinese medicine composition are made of the raw material of following parts by weight：
First dose：15-22 parts of the coptis, 15-22 parts of charred RADIX SANGUISORBAE, 6-9 parts of akebi, 5-8 parts of dragon's blood, 5-8 parts of Asian puccoon, duck bone 15-22
8-12 parts of part, 8-13 parts of chrysanthemum, 8-13 parts of dandelion, 8-10 parts of honey, 8-10 parts of lime and vitamin D；
Second dose：18-22 parts of duck oil, 5-10 parts of pearl powder, 8-12 parts of gypsum, 20-25 parts of aloe, 15-22 parts of egg white, beeswax
8-10 parts, 12-18 parts of 8-12 parts of vitamin A and vitamin E.
2. the external medicine composition for the treatment of burn as described in claim 1, the Chinese medicine composition is by following parts by weight
Raw material is made：
First dose：18 parts of the coptis, 18 parts of charred RADIX SANGUISORBAE, 7 parts of akebi, 7 parts of dragon's blood, 7 parts of Asian puccoon, 18 parts of duck bone, 10 parts of chrysanthemum, Pu Gong
10 parts of 10 parts of English, 9 parts of honey, 9 parts of lime and vitamin D；
Second dose：21 parts of duck oil, 7 parts of pearl powder, 10 parts of gypsum, 22 parts of aloe, 18 parts of egg white, 9 parts of beeswax, retinol1 0
15 parts of part and vitamin E.
3. a kind of preparation method of the external medicine composition for the treatment of burn as claimed in claim 1 or 2, which is characterized in that
First dose of preparation includes the following steps：
Step 1: the dragon's blood of above-mentioned parts by weight, chrysanthemum, dandelion and lime are dried, it is crushed to 140-200 mesh, mixing is equal
Fine powder material is obtained after even；
Step 2: being freeze-dried the duck bone of above-mentioned parts by weight, be crushed to 60-80 mesh, mix above-mentioned parts by weight the coptis,
Elm charcoal, akebi and Asian puccoon are placed in the 2-3 times of clear water measured and impregnate 1-2h, and Chinese medicine is exposed in high heat decoction to the water surface, is obtained by filtration
The dregs of a decoction and the first filtrate, are added the 6-8 times of ethanol water for measuring 40%-55%, refluxing extraction 2-3 times in the dregs of a decoction, and merging carries
Liquid is taken, the second filtrate is obtained by filtration, merges the first filtrate and the second filtrate, by large pore resin absorption column, with ethanol elution 2-3
It is secondary, eluent is collected, ethyl alcohol is recovered under reduced pressure, obtains liquid material；
Step 3: the fine powder material that step 1 obtains and the liquid material that step 2 obtains are mixed, honey is added, after stirring 8-10h,
First dose of suspension is made.
4. the preparation method of the external medicine composition for the treatment of burn as claimed in claim 3, which is characterized in that second dose
Preparation includes the following steps：
Step 4: the duck oil of above-mentioned weight fraction is melted, the beeswax, pearl powder and gypsum of above-mentioned parts by weight is added, stirs
It after 8-10h, is cooled to room temperature, for use；
Step 5: the vitamin A of above-mentioned parts by weight and vitamin E are dissolved in the egg white of above-mentioned parts by weight, stir
After 3-5h, for use；
Step 6: the aloe of above-mentioned parts by weight is cut into segment, using CO2Supercritical extract obtains aloe extract；
Step 7: by Step 4: Step 5: the product that step 6 obtains stirs 8-10h at normal temperatures, the 2-3 times of water measured is added,
After standing, 5-8min is centrifuged under the rotating speed of 2000r/min, liquid separation in separatory funnel is placed in and obtains oil phase, is made second dose
Medicinal extract.
5. the preparation method of the external medicine composition for the treatment of burn as claimed in claim 3, which is characterized in that the honey
Preparation method be：Take the honey in the new honeycomb that spring acquires, tempered with slow boiling, filter off foam, be added after cooling smash to pieces it is fresh
Dried peppermint leaf and Bulbus Lilii leaf, stir 2~3h, sieve with 100 mesh sieve, be added vitamin D, stirring 2~3h to get.
6. the preparation method of the external medicine composition for the treatment of burn as claimed in claim 4, which is characterized in that the bee
The preparation method of wax is：It will be placed in steamer after the new honeycomb removal honey of spring acquisition, is steamed with the alcoholic solution of 75-80% volume fractions
2-3h processed, controlled at 60-70 DEG C, until beeswax is melted to liquid, fresh dried peppermint leaf, which is layered on layer 2-3 on funnel, substitutes filter
Paper, filtering, by obtained filtrate cool down to get.
7. the preparation method of the external medicine composition for the treatment of burn as claimed in claim 3, which is characterized in that step 2
In, the elution refers to using the 1-2 times of ethyl alcohol measured, and flow velocity is to measure for 1-2 times per hour.
8. the preparation method of the external medicine composition for the treatment of burn as claimed in claim 4, which is characterized in that described
CO2The operating condition of supercritical extract is：30~35MPa, 40~45 DEG C, 2~3h.
9. the preparation method of the external medicine composition for the treatment of burn as claimed in claim 4, which is characterized in that the duck oil
For the oil of the rendering of fats of duck, it is added the 2-3 times of water measured, after standing, centrifuges 5-8min under the rotating speed of 2000r/min, set
In the oil phase that separatory funnel liquid separation obtains to get duck oil.
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Effective date of registration: 20230808 Address after: Room 6-522, Building 4, No. 188 Zijinghua North Road, Xihu District, Hangzhou City, Zhejiang Province, 310000 Patentee after: Hangzhou Mengmian Guaishou Technology Co.,Ltd. Address before: No. 10-4, Dashi 19th Team, Dashi Village, Luojiang Town, Rongxian County, Guangxi Zhuang Autonomous Region, 537522 Patentee before: Liang Yi |