CN104719874A - Ganoderma lucidum full-ingredient mixed chewable tablets and preparation method thereof - Google Patents
Ganoderma lucidum full-ingredient mixed chewable tablets and preparation method thereof Download PDFInfo
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Abstract
The invention relates to ganoderma lucidum full-ingredient mixed chewable tablets and a preparation method thereof. The ganoderma lucidum full-ingredient mixed chewable tablets comprise, by weight percentage, 50-80% of ganoderma lucidum fruiting body superfine powder, 10-30% of sporoderm-broken spore powder processed by beta cyclodextrin, 5-10% of magnesium stearate, 5-10% of xylitol and 5% of low-substituted hydroxy propyl cellulose, wherein the raw materials are mixed to form mixed powder, and the mixed powder are tableted; beta cyclodextrin accounting for 5% of the mass of the sporoderm-broken spore powder is added during sporoderm-broken spore powder processing. The ganoderma lucidum full-ingredient mixed chewable tablets have the advantages that the ganoderma lucidum fruiting bodies and the spore powder are combined, full ingredients of ganoderma lucidum are used for granulation, comprehensive nutrition is achieved, the superfine powder can be easily absorbed by human bodies, ganoderma lucidum nutritional value and healthcare effect are increased greatly, and the problems that ganoderma lucidum products on the market contain few effective bioactive ingredients and most effective ingredients in ganoderma lucidum are not fully utilized are solved.
Description
One, technical field
What the present invention relates to is field of health care food, and what be specifically related to is a kind of glossy ganoderma full composition mixing chewable tablets and preparation method thereof.
Two, background technology
Glossy ganoderma is one of famous medicinal fungi, over the past thousands of years, is considered as celestial grass by among the people always.The ancient book such as Shennong's Herbal and Compendium of Material Medica is recorded, glossy ganoderma has " the beneficial motive ", " entering the heart being responsible for production of blood ", " helping the heart to fill arteries and veins ", " calming the nerves ", " beneficial lung qi ", " beneficial vital essence ", the effect such as " hard muscles and bones ", glossy ganoderma is classified as top grade.The active ingredient of glossy ganoderma has GL-B class, triterpenes, ucleosides, sterols, alkaloids, furan derivatives, amino acid, polypeptide class, mineral element, aliphatic acid etc.
At present, the ganoderma lucidum product on market is generally ganoderma lucidum fruitbody or lucidum spore powder two kinds of products, or above-mentioned two kinds of functional components extracted for raw material.
Ganoderma lucidum fruitbody has protective effect to the hepatic injury that multiple physics and chemistry and biological factor cause.No matter before liver damage occurs or after generation, take glossy ganoderma and all can protect liver, promotion liver, to the metabolism of medicine, poisonous substance, alleviates hepatic injury.Wherein water-soluble polysaccharide, can promote that tissue is to the utilization of sugar, alleviates the occurring degree of Non-Insulin Dependent Diabetes Mellitus.And glossy ganoderma can coronary artery dilator effectively, improves Myocardial Microcirculation, strengthens the supply of myocardium oxygen and energy, have protective effect to myocardial ischemia, can be widely used in treatment and the prevention of coronary heart diseases and angina pectoris etc.To high fat of blood patient, can obviously reduce cholesterolemia, lipoprotein and triglyceride, and the formation of energy prevention of arterial AP.Improve local microcirculation, stop platelet aggregation.Simultaneously, glossy ganoderma also contains the composition of check melanin and the multiple trace element etc. to skin beneficiating, and these compositions by reducing human free radical, can accelerate the regeneration of cell, increase the thickness of skin and increase collagen, reaching plump skin, eliminating the effect of microgroove and wrinkle.Polysaccharide component wherein by keeping and regulation of skin water-based, can recover skin elasticity, making skin wet, exquisiteness.Medicinal aspect can cure mainly has no peace of mind, insomnia, palpitation with fear, coughs that to breathe heavily phlegm many, the illnesss such as consumptive disease.Therefore, glossy ganoderma both can be used as drug administration to reach the object for the treatment of, can be used as again health food edible with prophylactic generation for a long time.
Polysaccharide in lucidum spore powder can strengthen immune function, prevention and therapy tumour and cancer; Reduce blood pressure, the generation of angiocardiopathy preventing; Stimulate the secretion of insulin, reduce blood sugar concentration; Accelerate blood microcirculation, improve blood oxygen ability, reduce the invalid oxygen demand under body inactive state, eliminate interior free yl, improve the closed stratum of body cell film, anti-radiation, life-extending etc.Be rich in triterpenes ganoderic acid in conidia powder, ganoderic acid can improve microcirculation, reduces cholesterol, avoids vascular sclerosis; Liver, spleen and functions of intestines and stomach can be strengthened simultaneously, perfect Alimentary running.Because being rich in natural organic germanium, it can strengthen blood of human body keeping amount, promotes hemetaboly, eliminates interior free yl, prevents cell senescence; And electronics can be captured from cancer cell, its current potential is declined, thus inhibition cancer cell worsen and diffusion.The adenosine be rich in can suppress platelet aggregation, prevent thrombosis.Trace element Organic Selenium can anti-cancer in advance, eases the pain, prevents prostatic lesion, with vitamin C and use, can prevention of cardiac, and enhancement function.
At present, the product of ganoderma lucidum fruitbody and the full composition of conidia powder lacks, and effective bioactive ingredients that on market, ganoderma lucidum product contains is less, mostly is the extract of ganoderma lucidum fruitbody or conidia powder single product or active ingredient, most of active ingredient in lucid ganoderma is underutilized.General just to keep healthy or medicinal, the simple ganoderma lucidum fruitbody that utilizes produces tablet, or lucidum spore powder is made capsule product, does not find the product effectively combined by both full compositions.
Three, summary of the invention
The object of this invention is to provide a kind of glossy ganoderma full composition mixing chewable tablets, this glossy ganoderma full composition mixing chewable tablets is single for solving in prior art ganoderma lucidum product on market, and the effective bioactive ingredients contained is less, the problem that in lucid ganoderma, most of active ingredient is underutilized, another object of the present invention is to provide the preparation method of this glossy ganoderma full composition mixing chewable tablets.
The technical solution used in the present invention is: after this glossy ganoderma full composition mixing chewable tablets is mixed to form mixed powder by ganoderma lucidum fruitbody Ultramicro-powder 50%-80% by weight percentage, spore powder with crushed sporoderm 10%-30%, dolomol 5%-10% with beta cyclodextrin process, xylitol 5%-10%, low-substituted hydroxypropyl cellulose 5%, then formed by mixed powder compressing tablet; During process spore powder with crushed sporoderm, the addition of beta cyclodextrin is 5% of spore powder with crushed sporoderm quality.
Above-mentioned glossy ganoderma full composition mixing chewable tablets preparation method:
(1), lucidum spore powder carries out super-micro wall-broken process, and adds the embedding that beta cyclodextrin carries out active ingredient, and wherein beta cyclodextrin addition is 5% of conidia powder quality;
(2), get ganoderma lucidum fruitbody Ultramicro-powder 50%-80% by weight percentage, spore powder with crushed sporoderm 10%-30%, dolomol 5%-10%, xylitol 5%-10%, low-substituted hydroxypropyl cellulose 5% that step (1) processes, xylitol being dissolved in concentration of volume percent is in the alcoholic solution of 50%, progressively add other described each composition, limit edged stirs, to mixing, cross 80 mesh sieves, being dried to moisture is 6%-8%, makes ganoderma lucidum fruitbody Ultramicro-powder and the full composition mixed powder of spore powder with crushed sporoderm;
(3) mixed powder that step (2) is made is carried out compressing tablet, be ganoderma lucidum fruitbody and conidia powder full composition mixed powder chewable tablets.
Ganoderma lucidum fruitbody and the full composition mixed powder of conidia powder in such scheme, wherein full composition is the integral part of fructification after glossy ganoderma self-sow maturation and conidia powder, does not carry out extraction or the removal of any active ingredient.
Beneficial effect:
1, ganoderma lucidum fruitbody and conidia powder combine by the present invention, and use its full composition granulation, comprehensive nutrition, Ultramicro-powder is easy to absorption of human body, not only drastically increases effect that ganoderma lucidum is worth and keeps healthy, and good looking appearance, be easy to carry about with one, be convenient to eat, there is wide development and application prospect, solve effective bioactive ingredients that in prior art, on market, ganoderma lucidum product contains less, the problem that in lucid ganoderma, most of active ingredient is underutilized.
2, the glossy ganoderma full composition mixing chewable tablets obtained by the present invention is that market provides a kind of natural health products.Product is of high nutritive value, forming, sucks and namely changes, and has light conidia powder fragrance and the poor taste of joyful ganoderma lucidum fruitbody, is extremely applicable to person in middle and old age, brain worker and the crowd that just recovers from a dangerous illness.Solve the difficult compressing tablet of conidia powder on market, do the technical barrier of capsule only, greatly widened the market of single fructification tablet, the research and development for ganoderma lucidum product open a new way simultaneously.
3, glossy ganoderma and xylitol are reasonably prepared by the present invention, and its health-care effect is increased greatly.Xylitol is the intermediate of human body carbohydate metabolism, lack under insulin affects glycometabolism situation in vivo, need not promote by pancreas islet, xylitol also can permeate through cell membranes, is absorbed by tissue utilization, promote liver glycogen synthesis, for cell with nutrition and energy, and blood glucose value can not be caused to raise, reduce the consumption of protein in fat and hepatic tissue, liver function and lipotropic effect are improved to hepatopath, B-mode metastatic hepatitis, chronic hepatitis B and cirrhosis can be treated; Simultaneously can prevent carious tooth and reduce the generation of dental plaque, consolidating tooth.
4, the conidia powder active component after broken wall is easily absorbed by the body, but active component is easy to inactivation simultaneously, occurs rotten, adds appropriate beta cyclodextrin wherein, can effectively prevent active ingredient in conidia powder oxidized, retain nutrition and activity to a greater extent.
5, application claims tooling cost is little, is applicable to standardized production.
Four, detailed description of the invention
The present invention is described further below:
embodiment 1:
After this glossy ganoderma full composition mixing chewable tablets is mixed to form mixed powder by ganoderma lucidum fruitbody Ultramicro-powder 50% by weight percentage, the spore powder with crushed sporoderm 30% with beta cyclodextrin process, dolomol 10%, xylitol 5%, low-substituted hydroxypropyl cellulose 5%, then mixed powder compressing tablet is formed; During process spore powder with crushed sporoderm, the addition of beta cyclodextrin is 5% of spore powder with crushed sporoderm quality.
Above-mentioned glossy ganoderma full composition mixing chewable tablets preparation method:
(1) ganoderma lucidum fruitbody, selected carries out removal of impurities, ultramicro grinding; Lucidum spore powder carries out super-micro wall-broken process, and adds beta cyclodextrin, and wherein beta cyclodextrin addition is 5% of conidia powder quality; Ganoderma lucidum fruitbody and lucidum spore powder are the integral parts of fructification after glossy ganoderma self-sow maturation and conidia powder, do not carry out extraction or the removal of any active ingredient.
(2), get ganoderma lucidum fruitbody Ultramicro-powder 50% by weight percentage, spore powder with crushed sporoderm 30%, dolomol 10%, xylitol 5%, low-substituted hydroxypropyl cellulose 5% that step (1) processes, xylitol being dissolved in concentration is 50%(V/V) alcoholic solution in, progressively add other described each composition, limit edged stirs, to mixing, cross 80 mesh sieves, being dried to moisture is 6%-8%, makes ganoderma lucidum fruitbody Ultramicro-powder and the full composition mixed powder of spore powder with crushed sporoderm;
(3) mixed powder that step (2) is made is carried out compressing tablet, be ganoderma lucidum fruitbody and conidia powder full composition mixed powder chewable tablets.
embodiment 2:
After this glossy ganoderma full composition mixing chewable tablets is mixed to form mixed powder by ganoderma lucidum fruitbody Ultramicro-powder 60% by weight percentage, the spore powder with crushed sporoderm 20% with beta cyclodextrin process, dolomol 5%, xylitol 10%, low-substituted hydroxypropyl cellulose 5%, then mixed powder compressing tablet is formed; During process spore powder with crushed sporoderm, the addition of beta cyclodextrin is 5% of spore powder with crushed sporoderm quality.
Above-mentioned glossy ganoderma full composition mixing chewable tablets preparation method:
(1), select ganoderma lucidum fruitbody and carry out removal of impurities, ultramicro grinding; Lucidum spore powder carries out super-micro wall-broken process, and adds beta cyclodextrin, and wherein beta cyclodextrin addition is 5% of conidia powder quality;
(2), get ganoderma lucidum fruitbody Ultramicro-powder 60% by weight percentage, spore powder with crushed sporoderm 20%, dolomol 5%, xylitol 10%, low-substituted hydroxypropyl cellulose 5% that step (1) processes, xylitol being dissolved in concentration is 50%(V/V) alcoholic solution in, progressively add other described each composition, limit edged stirs, to mixing, cross 80 mesh sieves, being dried to moisture is 6%-8%, makes ganoderma lucidum fruitbody Ultramicro-powder and the full composition mixed powder of spore powder with crushed sporoderm;
(3) mixed powder that step (2) is made is carried out compressing tablet, be ganoderma lucidum fruitbody and conidia powder full composition mixed powder chewable tablets.
embodiment 3:
After this glossy ganoderma full composition mixing chewable tablets is mixed to form mixed powder by ganoderma lucidum fruitbody Ultramicro-powder 70% by weight percentage, the spore powder with crushed sporoderm 15% with beta cyclodextrin process, dolomol 5%, xylitol 5%, low-substituted hydroxypropyl cellulose 5%, then mixed powder compressing tablet is formed; During process spore powder with crushed sporoderm, the addition of beta cyclodextrin is 5% of spore powder with crushed sporoderm quality.
Above-mentioned glossy ganoderma full composition mixing chewable tablets preparation method:
(1), select ganoderma lucidum fruitbody and carry out removal of impurities, ultramicro grinding; Lucidum spore powder carries out super-micro wall-broken process, and adds beta cyclodextrin, and wherein beta cyclodextrin addition is 5% of conidia powder quality;
(2), get ganoderma lucidum fruitbody Ultramicro-powder 70% by weight percentage, spore powder with crushed sporoderm 15%, dolomol 5%, xylitol 5%, low-substituted hydroxypropyl cellulose 5% that step (1) processes, xylitol being dissolved in concentration is 50%(V/V) alcoholic solution in, progressively add other described each composition, limit edged stirs, to mixing, cross 80 mesh sieves, being dried to moisture is 6%-8%, makes ganoderma lucidum fruitbody Ultramicro-powder and the full composition mixed powder of spore powder with crushed sporoderm;
(3) mixed powder that step (2) is made is carried out compressing tablet, be ganoderma lucidum fruitbody and conidia powder full composition mixed powder chewable tablets.
embodiment 4:
After this glossy ganoderma full composition mixing chewable tablets is mixed to form mixed powder by ganoderma lucidum fruitbody Ultramicro-powder 80% by weight percentage, the spore powder with crushed sporoderm 10% with beta cyclodextrin process, dolomol 5%, xylitol 5%, low-substituted hydroxypropyl cellulose 5%, then mixed powder compressing tablet is formed; During process spore powder with crushed sporoderm, the addition of beta cyclodextrin is 5% of spore powder with crushed sporoderm quality.
Above-mentioned glossy ganoderma full composition mixing chewable tablets preparation method:
(1), select ganoderma lucidum fruitbody and carry out removal of impurities, ultramicro grinding; Lucidum spore powder carries out super-micro wall-broken process, and adds beta cyclodextrin, and wherein beta cyclodextrin addition is 5% of conidia powder quality;
(2), get ganoderma lucidum fruitbody Ultramicro-powder 80% by weight percentage, spore powder with crushed sporoderm 10%, dolomol 5%, xylitol 5%, low-substituted hydroxypropyl cellulose 5% that step (1) processes, xylitol being dissolved in concentration is 50%(V/V) alcoholic solution in, progressively add other described each composition, limit edged stirs, to mixing, cross 80 mesh sieves, being dried to moisture is 6%-8%, makes ganoderma lucidum fruitbody Ultramicro-powder and the full composition mixed powder of spore powder with crushed sporoderm;
(3) mixed powder that step (2) is made is carried out compressing tablet, be ganoderma lucidum fruitbody and conidia powder full composition mixed powder chewable tablets.
The present invention can serve as health food and directly eat, and overcomes drawback that active ingredient traditionally needs long-time infusion just can be utilized and has the easily digested advantage of broken wall artifact active component, being easy to carry, instant good.
Claims (3)
1. a glossy ganoderma full composition mixing chewable tablets, it is characterized in that: after this glossy ganoderma full composition mixing chewable tablets is mixed to form mixed powder by ganoderma lucidum fruitbody Ultramicro-powder 50%-80% by weight percentage, spore powder with crushed sporoderm 10%-30%, dolomol 5%-10% with beta cyclodextrin process, xylitol 5%-10%, low-substituted hydroxypropyl cellulose 5%, then mixed powder compressing tablet is formed; During process spore powder with crushed sporoderm, the addition of beta cyclodextrin is 5% of spore powder with crushed sporoderm quality.
2. a preparation method for glossy ganoderma according to claim 1 full composition mixing chewable tablets, is characterized in that: (1), lucidum spore powder carry out super-micro wall-broken process, and add beta cyclodextrin, and wherein beta cyclodextrin addition is 5% of conidia powder quality;
(2), get ganoderma lucidum fruitbody Ultramicro-powder 50%-80% by weight percentage, spore powder with crushed sporoderm 10%-30%, dolomol 5%-10%, xylitol 5%-10%, low-substituted hydroxypropyl cellulose 5% that step (1) processes, xylitol being dissolved in concentration of volume percent is in the alcoholic solution of 50%, progressively add other described each component, limit edged stirs, to mixing, cross 80 mesh sieves, being dried to moisture is 6%-8%, makes ganoderma lucidum fruitbody Ultramicro-powder and the full composition mixed powder of spore powder with crushed sporoderm;
(3) mixed powder that step (2) is made is carried out compressing tablet, be ganoderma lucidum fruitbody and conidia powder full composition mixed powder chewable tablets.
3. the preparation method of glossy ganoderma according to claim 2 full composition mixing chewable tablets, it is characterized in that: described ganoderma lucidum fruitbody and the full composition mixed powder of conidia powder, wherein full composition is the integral part of fructification after glossy ganoderma self-sow maturation and conidia powder, does not carry out extraction or the removal of any active ingredient.
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| CN105326866A (en) * | 2015-11-25 | 2016-02-17 | 苏州普罗达生物科技有限公司 | Method for carrying out superfine wall breaking and smashing on boletus |
| CN105341232A (en) * | 2015-12-10 | 2016-02-24 | 湖北省农业科学院农产品加工与核农技术研究所 | Compound sustained release particle tea and preparation process thereof |
| CN105475990A (en) * | 2015-11-30 | 2016-04-13 | 杭州鑫伟低碳技术研发有限公司 | Method for manufacturing Ganoderma lucidum spore powder or Ganoderma lucidum polysaccharide suspension gel |
| CN106176841A (en) * | 2016-08-17 | 2016-12-07 | 四川理工学院 | A kind of Penthorum chinense whole part mixing chewable tablet and preparation method thereof |
| CN107334788A (en) * | 2017-06-30 | 2017-11-10 | 中国医学科学院药用植物研究所海南分所 | A kind of anti-liver tumour glossy ganoderma powder and its preparation method and application |
| JP2018070489A (en) * | 2016-10-27 | 2018-05-10 | Tdk株式会社 | Melanogenesis inhibitor |
| CN111643531A (en) * | 2020-07-10 | 2020-09-11 | 浙江海兴药业有限公司 | Compound ganoderma lucidum wall-broken spore powder and preparation method thereof |
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