CN104645228A - Traditional Chinese medicine composition for treating prosopalgia and preparation method of traditional Chinese medicine composition - Google Patents

Abstract

The invention relates to a traditional Chinese medicine composition for treating prosopalgia and a preparation method of the traditional Chinese medicine composition, and belongs to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition comprises the following raw materials by weight: 12g of mulberry twig, 12g of earthworms, 12g of paris polyphylla, 12g of kadsura pepper stem, 12g of Chinese starjasmine stem, 12g of honeysuckle stem, 12g of centipedes, 12g of scorpion, 12g of cortex acanthopanacis, 12g of curcuma aromatica, 12g of cinnamon, 12g of ligusticum wallichii, 12g of paeony, 12g of divaricate saposhnikovia root and 10g of liquorice. The traditional Chinese medicine composition disclosed by the invention can be prepared into two forms of a wine and a fumigant; coordination treatment of orally taking medicinal liquor and traditional Chinese medicine fumigation is reached; the traditional Chinese medicine composition is significant in effect; the total effective rate is improved; the recovery rate is improved; and the recurrence rate is lowered.

Description

One treats prosopalgic Chinese medicine composition and preparation method thereof

Technical field

The present invention relates to one and treat prosopalgic Chinese medicine composition and preparation method thereof, belong to technical field of Chinese medicines.

Background technology

Trigeminal neuralgia is modal cranial nerve diseases, and with the violent pain of the paroxysmal of recurrent exerbation in a side surface part nervi trigeminus areal area for main manifestations, the sickness rate 52.2/10 ten thousand of domestic statistics, female is slightly more than man, and sickness rate can increase with the age.Trigeminal neuralgia is multiple is born in middle-aged and elderly people, R)L.The feature of this disease is: in Head And Face nervi trigeminus distributed areas, and morbidity is suddenly sent out, all standing, lightning sample, the sample that lancinates, burnt sample.Speak, wash one's face, brush teeth or mild wind strokes face, having an intense pain when all can cause paroxysmal when even walking.Pain lasts several seconds or several minutes, and pain is periodical attack, and the outbreak intermission is the same with normal person.

The treatment of doctor trained in Western medicine is generally pharmacotherapy or operative treatment.Western medicine mainly contains carbamazepine, phenytoin sodium, clonazepam, these medicines can play the effect of temporary transient pain relieving or alleviation, but long-term taking can have dependency to medicine, and there will be various side effect as drowsiness in dizziness weak, vomiting, granulocytopenia, even cause aplastic anemia, toxic hepatitis etc.; Although operative treatment can obtain good analgesic effect in a short time, operation risk is large, and patient will bear very large misery and the risk of postoperative infection, and once recurrence is difficult to perform an operation again.

Summary of the invention

For solving prior art Problems existing, the object of the present invention is to provide one to treat prosopalgic Chinese medicine composition and preparation method thereof, patient's oral medicinal liquor Combined Traditional Chinese Medicine Fumigate in Treating Be very effective, total effective rate improves, cure rate improves, and relapse rate reduces.

Technical scheme of the present invention is:

One treats prosopalgic Chinese medicine composition, it is characterized in that, comprises the raw material of following weight:

Ramulus Mori 12g, Pheretima 12g, Rhizoma Paridis 12g, Caulis Piperis Kadsurae 12g, Caulis Trachelospermi 12g, Caulis Lonicerae 12g, Scolopendra 12g, Scorpio 12g, Cortex Acanthopancis 12g, Radix Curcumae 12g, Cortex Cinnamomi 12g, Rhizoma Chuanxiong 12g, Radix Paeoniae 12g, Radix Saposhnikoviae 12g, Radix Glycyrrhizae 10g.

Further, the raw material of following weight portion can also be comprised:

Semen Persicae 10g, Flos Carthami 10g, Radix Angelicae Sinensis 10g, Caulis Spatholobi 10g, Eupolyphaga Seu Steleophaga 10g.

Further, the raw material of following weight portion can also be comprised:

Radix Aconiti 10g, Ramulus Cinnamomi 10g, Herba Ephedrae 10g, Rhizoma Et Radix Notopterygii 10g, Herba Asari 10g, Herba Lycopodii 10g.

Further, the raw material of following weight portion can also be comprised:

Fructus Lycii 10g, Radix Rehmanniae 10g, Rhizoma Dioscoreae 10g, Fructus Corni 10g, Radix Adenophorae (Radix Glehniae) 10g.

Further, the raw material of following weight portion can also be comprised:

Rhizoma Gastrodiae 10g, Ramulus Uncariae Cum Uncis 10g, Concha Margaritifera 10g, Concha Haliotidis 10g.

Further, the raw material of following weight portion can also be comprised: Rhizoma Coptidis 10g, Flos Chrysanthemi 10g, Herba Dendrobii 10g, Fructus Viticis 10g.

The present invention also provides a kind of preparation method for the treatment of prosopalgic Chinese medicine composition, it is characterized in that, comprises the following steps:

One, get the raw materials ready:

Ramulus Mori: clean, run through, cut sheet, dry; Pheretima: removing impurity, clean, cutting, drying; Rhizoma Paridis: clean, cut into slices, dry; Caulis Piperis Kadsurae: removing impurity, soaks, runs through, cuts sheet, dry; Caulis Trachelospermi: removing impurity, clean, slightly profit, cutting, drying; Scolopendra a: bamboo chip, cleans, and low baking temperature roasting is yellow, the section of cutting; Cortex Acanthopancis: removing impurity, cleans, runs through, cuts sheet, dry; Radix Curcumae: clean, run through, shave, drying; Or clean, dry, smash; Cortex Cinnamomi: removing impurity and rough bark, the used time smashs to pieces; Rhizoma Chuanxiong: removing impurity, separately size, slightly bubble, clean, run through, shave, drying; Radix Saposhnikoviae: removing impurity, cleans, runs through, cuts sheet, drying; Radix Glycyrrhizae: removing impurity, cleans, runs through, cuts sheet, drying;

Semen Persicae: removing impurity, the used time smashs to pieces; Flos Carthami: pick clean impurity, removing stem and leaf, base of a fruit head, dry; Radix Angelicae Sinensis: removing impurity, cleans, runs through, shave, dry or cold drying.Caulis Spatholobi: removing impurity, cleans, runs through, shreds, dries; Eupolyphaga Seu Steleophaga: clean with clear water, then with drying after salt decocting in water or low baking temperature oven dry;

Radix Aconiti: pick decontamination, cleans ash bits, dries.Ramulus Cinnamomi: removing impurity, slightly steeps, cleans, runs through, shave, to dry; Herba Ephedrae: removing woody stems, undesirable root and impurity, cutting, dries; Rhizoma Et Radix Notopterygii: removing impurity, cleans, runs through, cuts sheet, dries; Herba Asari: removing impurity, spray clear water, slightly moistens, cutting, to dry; Herba Lycopodii: removing impurity and rough bark, the used time smashs to pieces;

Fructus Lycii: clean impurity of winnowing with a dustpan, plucks residual stalk and the base of a fruit; Radix Rehmanniae: slightly steep with water, cleans sediment contamination, pulls out and stew to moisten, and section is dried or dried; Rhizoma Dioscoreae: removing impurity, separately size, bubble profit, to thoroughly, cuts sheet, dry; Fructus Corni: removing impurity and residual pit, section; Radix Adenophorae (Radix Glehniae): get crude drug, removing impurity and reed head, clean, run through, cut sheet, drying;

Rhizoma Gastrodiae: pick decontamination, size stepping, is soaked in water to seventy percent thoroughly, pull out, slightly dry in the air, then profit is even to inside and outside humidity, cuts into slices, dries; Ramulus Uncariae Cum Uncis: pick old stalk, impurity, clean, dry; Concha Margaritifera: removing impurity, smashes, and is pulverized by the Fructus Lycii of removing impurity at-30 DEG C of lyophilization post-treatment; Concha Haliotidis: get clean Concha Haliotidis, is calcined to crisp according to method of direct calcination; Flos Chrysanthemi: pick clean leaf stalk, anthocaulus and spare impurity;

Rhizoma Coptidis: removing impurity, runs through rear shave, dries, or smashs to pieces the used time; Flos Chrysanthemi: pick clean leaf stalk, anthocaulus and spare impurity, after drying moisture, dry in the sun.Herba Dendrobii: dry product removing undesirable root, clean, cutting, drying.Fructus Viticis: removing impurity.

Two, prepare:

Chinese medicine composition of the present invention can make medicated wine or fumigant, and the preparation method of medicated wine comprises the following steps:

1. take raw material according to above-mentioned weight proportion, take the needed raw material of getting the raw materials ready and be crushed to 120 order fine powders;

2. needed raw material fine powder is all put into marmite, add water to and exceed powder 10 cm, soak about 4 hours, then heated and boiled 1 hour, after filtration, obtains medicinal liquid one;

3. the medicinal residues after step 2. middle filtration are added water again and decoct 1 time, after filtration again in right amount, obtain medicinal liquid two;

4. merge medicinal liquid one and medicinal liquid two, leave standstill after 6 hours, then get supernatant heating and be condensed into paste, be cooled to room temperature;

5. by step 4. in paste medicinal liquid be mixed into the Chinese liquor of equivalent spirituosity amount at 50%-60%, mix homogeneously, is placed in container, sealing, take out supernatant after about 7 days, obtain medicated wine disclosed by the invention;

Usage and dosage: daily 2 ~ 3 times, each 10ml.

The preparation method of fumigant comprises the following steps:

(1) take the needed raw material of getting the raw materials ready and be crushed to 120 order fine powders;

(2) fine powder of step (1) is all put into marmite, add water to and exceed powder 10 cm, soak about 2 hours, then heated and boiled 5 minutes, obtains fumigant disclosed by the invention.

Usage and dosage: get Medical gauze and cover on marmite, its disease smoked is picked up the ears hole and painful area 10-20 minute; Every day 2 ~ 3 times, every agent medicine 3 ~ 5 days, wind sheltering three days after smoked.

The pharmacological action of each component:

Ramulus Mori: bitter, flat, enters Liver Channel, wind-damp dispelling, sharp joint, row aqueous vapor; Pheretima: salty, cold, return liver, spleen, urinary bladder channel, heat clearing away is calmed the frightened, and dredging collateral, relievings asthma, diuresis; Rhizoma Paridis: bitter, cold, slightly poisonous; Caulis Piperis Kadsurae: pungent, bitter, tepor, returns Liver Channel, wind-damp dispelling, the meridian dredging, stopping numbness pain; Caulis Trachelospermi: bitter, is slightly cold, GUIXIN, liver, kidney channel, dispelling wind and removing obstruction in the collateral, and removing heat from blood is subsided a swelling; Caulis Lonicerae: sweet, cold, attach to the lung and stomach meridians, heat-clearing and toxic substances removing, dispelling wind dredging collateral; Scolopendra: pungent, temperature, poisonous, return Liver Channel, endogenous wind stopping spasmolytic, merit poison eliminating stagnation, removing obstruction in the collateral to relieve pain; Scorpio: pungent, flat, poisonous, return Liver Channel, endogenous wind stopping spasmolytic, dispersing pathogen accumulation, removing obstruction in the collateral to relieve pain; Cortex Acanthopancis: pungent, bitter, temperature, returns liver, kidney channel, wind-damp dispelling, invigorating the liver and kidney, bone and muscle strengthening; Radix Curcumae: pungent, bitter, cold, return liver, the heart, lung meridian, regulating qi to disperse stagnation, heart fire-clearing upset-relieving, promoting the function of the gallbladder to alleviate jaundice; Cortex Cinnamomi: pungent, sweet, hot greatly, return kidney, spleen, the heart, Liver Channel, mend fire supporing yang, let the fire back to its origin, dispersing cold for relieving pain, promoting blood circulation to restore menstrual flow; Rhizoma Chuanxiong: pungent, temperature, returns liver, gallbladder, pericardium channel, blood-activating and qi-promoting, wind-expelling pain-stopping; Radix Paeoniae: bitter in the mouth, flat, main pathogen stomachache, except arthralgia due to stagnation of blood, broken hard long-pending cold and heat, hernia abdominal mass, pain relieving, diuresis; Radix Saposhnikoviae: acrid, sweet, warm, returns bladder, liver, spleen channel, inducing diaphoresis to dispel wind, and victory is wet, relieving convulsion; Radix Glycyrrhizae: sweet, flat, GUIXIN, lung, spleen, stomach warp, invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription;

Semen Persicae: bitter, sweet, flat, GUIXIN, liver, large intestine channel, blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation; Flos Carthami: pungent, warm, enters the heart, Liver Channel, promoting blood circulation to restore menstrual flow, blood stasis removing pain relieving; Radix Angelicae Sinensis: sweet, pungent, warm, returns liver, the heart, spleen channel, enriches blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation; Caulis Spatholobi: bitter, sweet, temperature.Return liver, kidney channel.Enrich blood, invigorate blood circulation, dredging collateral; Eupolyphaga Seu Steleophaga: salty, cold; Slightly poisonous.Return Liver Channel.Removing blood stasis with potent drugs blood, reuniting the fractured tendons and bones.

Radix Aconiti: pungent, hot, poisonous, dispelling cold and dampness, loose ailment said due to cold or exposure, warming the meridian, pain relieving; Ramulus Cinnamomi: pungent, sweet, warm, GUIXIN, lung, urinary bladder channel, diaphoresis expelling pathogenic factors from muscles, promoting the flow of QI-blood by warming the meridian, supporing yang activating QI, the flat gas that spins; Herba Ephedrae: pungent, micro-hardship, temperature, returns lung, urinary bladder channel, diaphoresis cold expelling, depressed lung-energy dispersing, inducing diuresis to remove edema; Rhizoma Et Radix Notopterygii: pungent, bitter, temperature, returns bladder, kidney channel, cold expelling, dispels the wind, dehumidifying, pain relieving; Herba Asari: pungent, temperature, GUIXIN, lung, kidney channel, expelling wind and cold, understand things pain-stopping, warming the lung to resolve fluid-retention; Herba Lycopodii: toil, temperature, enters liver,spleen,kidney three warp, expelling wind and cold, dehumidifying detumescence, relaxing muscles and tendons to promote blood circulation; Cortex Cinnamomi: pungent, sweet, hot greatly, return kidney, spleen, the heart, Liver Channel, mend fire supporing yang, let the fire back to its origin, dispersing cold for relieving pain, promoting blood circulation to restore menstrual flow;

Fructus Lycii: sweet, flat, enter liver, kidney channel, nourishing kidney, lung moistening, tonifying liver, improving eyesight; Radix Rehmanniae: sweet, cold, GUIXIN, liver, kidney channel, clearing away heat and promoting production of body fluid, removing heat from blood, hemostasis; Rhizoma Dioscoreae: sweet, flat, return spleen, lung, kidney channel, spleen reinforcing nourishing the stomach, promote the production of body fluid lung benefiting, the kidney invigorating arresting seminal emission; Fructus Corni: sour, puckery, tepor, returns liver, kidney channel, liver and kidney tonifying, essence astringing and desertion stemming; Radix Adenophorae (Radix Glehniae): sweet in the mouth, micro-hardship, cold nature, returns lung, stomach warp, replenishing YIN and removing heat, moistening the lung and resolving phlegm, reinforcing stomach reg fluid.

Rhizoma Gastrodiae: sweet, flat, returns Liver Channel, suppressing the hyperactive liver to relieve the wind syndrome relieving convulsion; Ramulus Uncariae Cum Uncis: sweet, cool, return liver, pericardium channel, heat clearing away suppressing the hyperactive liver, dispelling wind and relieving convulsion; Concha Margaritifera: salty, cold, return liver, heart channel, suppressing the hyperactive liver and subsiding YANG, arresting convulsion improving eyesight.Concha Haliotidis: salty, cold, return Liver Channel, suppressing the hyperactive liver and subsiding YANG, liver heat removing and eyesight improving;

Rhizoma Coptidis: bitter, cold, GUIXIN, spleen, stomach, liver, gallbladder, large intestine channel, heat clearing and damp drying, eliminating fire and detoxication; Flos Chrysanthemi: bitter, is slightly cold, returns lung, Liver Channel, loose wind heat clearing away, suppressing the hyperactive liver improving eyesight; Herba Dendrobii: sweet, is slightly cold, and returns stomach, kidney channel, reinforcing stomach reg fluid, nourishing YIN and clearing away heat; Fructus Viticis: pungent, bitter, is slightly cold, and returns bladder, liver, stomach warp, dispelling wind and heat pathogens, the clear sharp head.

Chinese medicine thinks that trigeminal neuralgia belongs to " headache ", " wind syndrome of head " category, and how site of pathological change, at Head And Face, is subject to caused by disease by Head And Face three YANG meridians network.Its etiology and pathogenesis is comparatively complicated, in brief have diseases caused by exogenous pathogenic factor and internal injury point, simultaneously closely related with ailment said due to cold or exposure again.Generally diseases caused by exogenous pathogenic factor are caused a disease, and on high mountain peak, only wind can reach, and ailment said due to cold or exposure rises to be sent out, and easily violates women's head-ornaments, ailment said due to cold or exposure and cold, fire, expectorant, stasis of blood knot stasis of blood Head And Face, so that wind and cold stagnates, or wind-fire is burnt, or wind-phlegm is stopped up resistance three YANG meridians network and sends out as pain.Internal injury is caused a disease, and with scorching in stagnant heat in the liver and gall, stomach excessive heat, no matter hyperactivity of YANG due to deficiency of YIN and wind-transformation etc. are closely related is excess-fire or asthenic fire, all can pathogen upward attacking orifices in head, hinders Head And Face meridians and causes pain; Or by women's head-ornaments stagnation of QI-blood, block three YANG meridians network, stagnation of QI and blood may bring about pain, also for internal injury pathogenic because of.Exopathogen causes a disease, and with the passing of time do not heal, recurrent exerbation, often can follow in entering, heat-transformation impairment of YIN; And internal injury is caused a disease also many being invaded by exogenous pathogen, aggravate disease, therefore inside and outside combined pathogens is trouble is this pathogenetic another clinical characters.

From the traditional Chinese medical science pathogeny of primary disease, treat prosopalgic is the three YANG meridians network dredging Head And Face at all, and meridians pain is not then bitterly.Treatment takes into account inside and outside answering, planted agent's nourishing blood to suppress the hyperactive liver, clearing away heat-fire, enriching yin and nourishing kidney, and circulation of qi promoting of should dispeling the wind outward, dredging dredging collateral, can treat trigeminal neuralgia from source.

The prosopalgic Chinese medicine composition for the treatment of disclosed by the invention follows the inherent pathogeny of this disease, inside and outside take into account, treating both the principal and secondary aspects of a disease.Basic recipe for this, selects Ramulus Mori, Pheretima, Rhizoma Paridis, Caulis Piperis Kadsurae, Caulis Trachelospermi, Caulis Lonicerae, Scolopendra, Scorpio, Cortex Acanthopancis, Radix Curcumae, Cortex Cinnamomi, Rhizoma Chuanxiong, Radix Paeoniae, Radix Saposhnikoviae, Radix Glycyrrhizae with dredging the meridian, circulation of qi promoting of dispeling the wind, heat-clearing and toxic substances removing.According to patient other different performances and symptoms, dialectically again to divide and rule.To trigeminal neuralgia obstruction of collaterals by blood stasis disease, in basic prescription, be equipped with the Semen Persicae of blood circulation promoting and blood stasis dispelling, Flos Carthami, Radix Angelicae Sinensis, Caulis Spatholobi, Eupolyphaga Seu Steleophaga again; To trigeminal neuralgia wind-cold channel blocking network disease, in basic prescription, be equipped with the Radix Aconiti of expelling wind and cold, Ramulus Cinnamomi, Herba Ephedrae, Rhizoma Et Radix Notopterygii, Herba Asari, Herba Lycopodii, Cortex Cinnamomi again; To trigeminal neuralgia hyperactivity of YANG due to deficiency of YIN disease, in basic prescription, be equipped with the Fructus Lycii of enriching yin and nourishing kidney, Radix Rehmanniae, Rhizoma Dioscoreae, Fructus Corni, Radix Adenophorae (Radix Glehniae) again; To trigeminal neuralgia deficiency of the yin of the liver, excessive rising of liver-YANG disease, is equipped with the Rhizoma Gastrodiae of suppressing the hyperactive liver and subsiding YANG, Ramulus Uncariae Cum Uncis, Concha Margaritifera, Concha Haliotidis, Flos Chrysanthemi again in basic prescription; To the loss of trigeminal neuralgia stomach-Yin, gastric heat wind-transformation disease, is equipped with the Rhizoma Coptidis of eliminating stomach-fire, Flos Chrysanthemi, Herba Dendrobii, Fructus Viticis again in basic prescription.

The invention has the beneficial effects as follows:

1, the present invention is based on prosopalgic traditional Chinese medical science mechanism, determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, according to dissimilar, give immunotherapy targeted autoantibody, as to obstruction of collaterals by blood stasis disease, advocate blood circulation promoting and blood stasis dispelling, dispelling wind and removing obstruction in the collateral, heat-clearing and toxic substances removing; To hyperactivity of YANG due to deficiency of YIN disease, advocate enriching yin and nourishing kidney, dispelling wind and removing obstruction in the collateral, heat-clearing and toxic substances removing; To wind-cold channel blocking network disease, advocate expelling wind and cold, dredging the meridian, heat-clearing and toxic substances removing; To excessive rising of liver-YANG disease, advocate suppressing the hyperactive liver and subsiding YANG, dispelling wind and removing obstruction in the collateral, heat-clearing and toxic substances removing; To gastric heat wind-transformation disease, advocate eliminating stomach-fire, dispelling wind and removing obstruction in the collateral, heat-clearing and toxic substances removing.

In the manufacturing process of 2, medicated wine, select alcohol content at the Chinese liquor of 50%-60%, advantage is: the stripping being both conducive to effective ingredient in Chinese crude drug, and extraction time can not be made again long.If alcohol concentration is too high, a small amount of moisture in medical material can be made to be absorbed, and make medical material quality hard, effective ingredient is difficult to stripping; If alcohol concentration is too low, then extraction time extends relatively, the stripping of effective ingredient in guarantee medicine; In addition, after first required pulverizing medicinal materials being decocted, then be mixed in Chinese liquor and soak, compare direct being mixed in Chinese liquor by Chinese crude drug thin slice after getting the raw materials ready at present to soak, advantage is: less with capacity for liquor, when taking, vinosity does not weigh, be convenient to quote, especially particularly suitable to the people being bad to drink.

3, adopt and smoke the Therapeutic Method combined for oral administration and outward, internal and external application, to work along both lines, evident in efficacy.Herbal fumigation makes medicine be absorbed by skin surface, stratum corneum penetration and skin corium transhipment enter blood circulation and play drug effect, and " poison ", " pathogen ", " cold " of the vital organs of the human body in body can be made to be excreted rapidly by sweat gland, energy dredging the meridian, promotion qi-blood circulating, help to get rid of refuse and toxin in body, conditioner yin-yang, thus reach therapeutic purposes.

Below in conjunction with clinical data and model case, beneficial effect of the present invention is further illustrated.

One, clinical observation

1, clinical data:

Inclusive criteria: patient 120 example is included in this research altogether in, and patient is divided into four groups at random.Treatment group 30 example, wherein man 10 example, female 20 example; Contrast 1 group of 30 example, wherein man 12 example, female 18 example; Contrast 2 group of 30 example, wherein man 11, female 19 example; Contrast 3 group of 30 example, wherein man 10 example, female 20 example; The course of disease is (3 ± 1) moon, and four groups of clinical datas are through statistical procedures, and there was no significant difference (P > 0.05) has comparability.

2, diagnostic criteria: with reference to " internal disease diagnostic criteria ":

Face and forehead last for several seconds are to the ictal pain within 2 minutes; pain has following four features: pain is positioned at the distribution of nervi trigeminus more than 1 or 1; pain has suddenly, violent, show shallow, lancinate sample or burn the character of sample; by toggle area; or caused as taken food, speaking, wash one's face, brush teeth by some daily routines; completely normal twice interictal patient; during panic attacks; conjunctival congestion; shed tears, facial flushes, sialorrhea; the cause visible face spasm of pain repeatedly, does not have neural any defect finding.

3, Therapeutic Method:

The treatment group medicated wine that every day is prepared by oral Chinese medicine composition disclosed by the invention 3 times, each 10ml.Further, stifling 3 times of the fumigant every day applying that Chinese medicine composition disclosed by the invention makes, every agent medicine 5 days, wind sheltering three days after smoked.

Contrast patient's medicated wine that every day is prepared by oral Chinese medicine composition disclosed by the invention 3 times of 1 group, each 10ml.

Stifling 3 times of the patient contrasting 2 groups applies that Chinese medicine composition disclosed by the invention makes every day fumigant every day, every agent medicine 5 days, wind sheltering three days after smoked.

The patient contrasting 3 groups takes carbamazepine, starts a 0.1g, 2 times on the one; Increase by 0.1 ~ 0.2g every other day after second day, until pain relief, maintenance dose 0.4 ~ 0.8g every day, part vic; Maximum amount is no more than 1.2g every day.

4, efficacy assessment standard: with reference to " Chinese medical disease Standardization of diagnosis and curative effect ", efficacy determination based on transference cure, and changes situation with reference to sign etc., is divided into healing, effective, effective, invalid level Four.

Cure: symptom and sign all disappear, after treatment, pain disappears, and follows up a case by regular visits to and does not recur half a year;

Effective: symptom and sign are obviously improved, after medication, pain disappears, and follow up a case by regular visits in half a year and have recurrence (> 3 months), then medication is still effective;

Effective: symptom and sign have certain improvement, remission after medication, but recurrence in 1-2 month;

Do not heal: symptom and sign are all without improvement.

5, therapeutic outcome

As can be seen from the above table, apply traditional Chinese medicine composition for treating effects in treating trigeminal neuralgia disclosed by the invention remarkable, compared with the contrast 3 groups of taking separately carbamazepine, total effective rate improves, and cure rate improves, and relapse rate reduces; And oral medicinal liquor coordinates the therapeutic effect of the treatment group of fumigation treatment to be better than the contrast 1 group of independent oral medicinal liquor and the contrast 2 groups of independent fumigation treatment.

Two, model case

Case 1: man, 61 years old.Readme suffers from trigeminal neuralgia more than 5 years, brings out whenever touching facial or excited.On the right side of during outbreak, buccal, lower jaw are as lightning sample pain, have a strong impact on daily life.Once took carbamazepine, originally pain can be alleviated, rear poor effect, red tongue with thin and yellow fur, and there is petechia on tongue limit, deep and stringy pulse.

Method for the treatment of: dredge the meridian passage, circulation of qi promoting of dispeling the wind; Prescription: Ramulus Mori 12g, Pheretima 12g, Rhizoma Paridis 12g, Caulis Piperis Kadsurae 12g, Caulis Trachelospermi 12g, Caulis Lonicerae 12g, Scolopendra 12g, Scorpio 12g, Cortex Acanthopancis 12g, Radix Curcumae 12g, Cortex Cinnamomi 12g, Rhizoma Chuanxiong 12g, Radix Paeoniae 12g, Radix Saposhnikoviae 12g, Radix Glycyrrhizae 10g.

The medicated wine that oral Chinese medicine composition disclosed by the invention is made and cooperation herbal fumigation are treated, and treat after 20 days, pain degree, number of times all alleviate, and continue to take 10 days, and recovery from illness, follows up a case by regular visits to half a year and do not show effect.

Case 2: female, 56 years old.Left side gingiva, buccal pain, a burst of outbreak, the traction brilliance, cut-like pain, bore spine, have distending pain sense concurrently, therefore frown, make clicks during pain, often rubs pain side surface part, the micro-fiber crops of lip cheek car lower jaw part, buccal flushing with hand rubbing.The course of disease is touching, and pain is more heavier, and outbreak is frequent, and with the passing of time delay, does not heal.Purplish tongue, petechia, thready pulse.

Method for the treatment of: blood circulation promoting and blood stasis dispelling, dredge the meridian passage, circulation of qi promoting of dispeling the wind.Prescription: Ramulus Mori 12g, Pheretima 12g, Rhizoma Paridis 12g, Caulis Piperis Kadsurae 12g, Caulis Trachelospermi 12g, Caulis Lonicerae 12g, Scolopendra 12g, Scorpio 12g, Cortex Acanthopancis 12g, Radix Curcumae 12g, Cortex Cinnamomi 12g, Rhizoma Chuanxiong 12g, Radix Paeoniae 12g, Radix Saposhnikoviae 12g, Radix Glycyrrhizae 10g, Semen Persicae 10g, Flos Carthami 10g, Radix Angelicae Sinensis 10g, Caulis Spatholobi 10g, Eupolyphaga Seu Steleophaga 10g.

The medicated wine that oral Chinese medicine composition disclosed by the invention is made and cooperation are fumigated and are treated, and treat after 10 days, pain degree, number of times all alleviate, and continue to take 20 days, and recovery from illness, follows up a case by regular visits to half a year and do not show effect.

Case 3: man, 50 years old.Buccal paroxysm pain, pain is come as lightning, and for example normal after pain.Meet cold wind stroke face and pain occurs, obtain hot then alleviation of pain.Pale complexion during panic attacks, sheds tears, agraphia and feed, and conventional palm is covered the face or massage disease place, and face has obvious sensitive spot.Pale tongue or light red, thin white fur of tongue, floating pulse or stringy and thready pulse.

Method for the treatment of: expelling wind and cold, meridians dredging, circulation of qi promoting of dispeling the wind.Prescription: Ramulus Mori 12g, Pheretima 12g, Rhizoma Paridis 12g, Caulis Piperis Kadsurae 12g, Caulis Trachelospermi 12g, Caulis Lonicerae 12g, Scolopendra 12g, Scorpio 12g, Cortex Acanthopancis 12g, Radix Curcumae 12g, Cortex Cinnamomi 12g, Rhizoma Chuanxiong 12g, Radix Paeoniae 12g, Radix Saposhnikoviae 12g, Radix Glycyrrhizae 10g, Radix Aconiti 10g, Ramulus Cinnamomi 10g, Herba Ephedrae 10g, Rhizoma Et Radix Notopterygii 10g, Herba Asari 10g, Herba Lycopodii 10g.

The medicated wine that the prosopalgic Chinese medicine composition of oral treatment disclosed by the invention is made and cooperation fumigation treatment, treat after 15 days, pain degree, number of times all alleviate, and continue to take 15 courses for the treatment of, and recovery from illness, follows up a case by regular visits to half a year and do not show effect.

Case 4: female, 68 years old.Left side is from eye socket, nose to occipitalia paroxysmal hemicrania 13 years, and patient started left side eye socket, nose to occipitalia migraine before 13 years, and in paroxysmal, si dol urg, is difficult to stand, dare not diet.Have a meal, too loudly, nervous etc. all can to bring out.Hectic fever, flushed cheeks, night sweat, dysphoria with feverish sensation in the chest palms and soles, hemoptysis, blurring of vision, becomes thin or has a sleepless night, and numb contracture, agitation is easily thought.

Method for the treatment of: enriching yin and nourishing kidney, dredge the meridian passage, circulation of qi promoting of dispeling the wind; Prescription: Ramulus Mori 12g, Pheretima 12g, Rhizoma Paridis 12g, Caulis Piperis Kadsurae 12g, Caulis Trachelospermi 12g, Caulis Lonicerae 12g, Scolopendra 12g, Scorpio 12g, Cortex Acanthopancis 12g, Radix Curcumae 12g, Cortex Cinnamomi 12g, Rhizoma Chuanxiong 12g, Radix Paeoniae 12g, Radix Saposhnikoviae 12g, Radix Glycyrrhizae 10g, Fructus Lycii 10g, Radix Rehmanniae 10g, Rhizoma Dioscoreae 10g, Fructus Corni 10g, Radix Adenophorae (Radix Glehniae) 10g.

The medicated wine that the prosopalgic Chinese medicine composition of oral treatment disclosed by the invention is made and Combined Traditional Chinese Medicine Fumigate in Treating, treated after 30 days, and recovery from illness, recurs after half a year, former side's continual cure 30 days, and recovery from illness, follows up a case by regular visits to half a year and do not show effect.

Case 5: women, 63 years old.Because of toothache, pain and right side face, continuous more than ten skies are not understood, and acute when telling light when it is had a headache, send out variable interval, agonizing, time the most serious, Ipsilateral in sample pain of beating, and is shed tears with Ipsilateral, sialorrhea, heating sense in mouth.Slightly yellow near root of the tongue place.Dizzy distending pain, tinnitus, flushing, conjunctival congestion and swelling pain, being irritable and getting angry easily, dysphoria and insomnia or dreaminess, bitter taste xerostomia, constipation, short urination is yellow, menorrhagia, advanced, red tongue with yellow fur, wiry and frequent pulse.

Method for the treatment of: suppressing the hyperactive liver to relieve the wind syndrome, dredging the meridian, circulation of qi promoting of dispeling the wind; Prescription: Ramulus Mori 12g, Pheretima 12g, Rhizoma Paridis 12g, Caulis Piperis Kadsurae 12g, Caulis Trachelospermi 12g, Caulis Lonicerae 12g, Scolopendra 12g, Scorpio 12g, Cortex Acanthopancis 12g, Radix Curcumae 12g, Cortex Cinnamomi 12g, Rhizoma Chuanxiong 12g, Radix Paeoniae 12g, Radix Saposhnikoviae 12g, Radix Glycyrrhizae 10g, Rhizoma Gastrodiae 10g, Ramulus Uncariae Cum Uncis 10g, Concha Margaritifera 10g, Concha Haliotidis 10g.

The medicated wine that the prosopalgic Chinese medicine composition of oral treatment disclosed by the invention is made and Combined Traditional Chinese Medicine Fumigate in Treating, treated after 10 days, recovery from illness, recurs, former side's continual cure 15 days after 2 months, and recovery from illness, follows up a case by regular visits to half a year and do not show effect.

Case 6: women, 48 years old.Main manifestations is prosopodynia paroxysm, suddenly stops, and severe pain is as strong.Sharp ache, pain can be brought out, aversion to wind, heating, facial dry pharynx pharyngalgia, constipation with dry stool because actions such as speaking, take food, wash one's face stimulates, and yellow urine is few, red tongue, tongue fur BOHUANG, wiry and frequent pulse.

Method for the treatment of: clearing away heat-fire, meridians dredging, wind-expelling pain-stopping.Prescription: Ramulus Mori 12g, Pheretima 12g, Rhizoma Paridis 12g, Caulis Piperis Kadsurae 12g, Caulis Trachelospermi 12g, Caulis Lonicerae 12g, Scolopendra 12g, Scorpio 12g, Cortex Acanthopancis 12g, Radix Curcumae 12g, Cortex Cinnamomi 12g, Rhizoma Chuanxiong 12g, Radix Paeoniae 12g, Radix Saposhnikoviae 12g, Radix Glycyrrhizae 10g, Rhizoma Coptidis 10g, Flos Chrysanthemi 10g, Herba Dendrobii 10g, Fructus Viticis 10g.

The medicated wine that the prosopalgic Chinese medicine composition of oral treatment disclosed by the invention is made and Combined Traditional Chinese Medicine Fumigate in Treating, after treatment 30, recovery from illness, follows up a case by regular visits to half a year and does not show effect.

Detailed description of the invention

Embodiment 1:

One treats prosopalgic Chinese medicine composition, comprises the raw material of following weight:

Ramulus Mori 12g, Pheretima 12g, Rhizoma Paridis 12g, Caulis Piperis Kadsurae 12g, Caulis Trachelospermi 12g, Caulis Lonicerae 12g, Scolopendra 12g, Scorpio 12g, Cortex Acanthopancis 12g, Radix Curcumae 12g, Cortex Cinnamomi 12g, Rhizoma Chuanxiong 12g, Radix Paeoniae 12g, Radix Saposhnikoviae 12g, Radix Glycyrrhizae 10g.

The preparation method of medicated wine comprises the following steps:

1. take the needed raw material of getting the raw materials ready and be crushed to 120 order fine powders;

2. needed raw material fine powder is all put into marmite, add water to and exceed powder 10 cm, soak about 4 hours, then heated and boiled 1 hour, after filtration, obtains medicinal liquid one;

3. the medicinal residues after step 2. middle filtration are added water again and decoct 1 time, after filtration again in right amount, obtain medicinal liquid two;

4. merge medicinal liquid one and medicinal liquid two, leave standstill after 6 hours, then get supernatant heating and be condensed into paste,

Be cooled to room temperature;

5. by step 4. in paste medicinal liquid be mixed into the Chinese liquor of equivalent spirituosity amount at 50%-60%, mix homogeneously, is placed in container, sealing, take out supernatant after about 7 days, obtain medicated wine disclosed by the invention;

Usage and dosage: daily 2 ~ 3 times, each 10ml.

The preparation method of fumigant comprises the following steps:

(1) take the needed raw material of getting the raw materials ready and be crushed to 120 order fine powders;

(2) fine powder of step (1) is all put into marmite, add water to and exceed powder 10 cm, soak about 2 hours, then heated and boiled 5 minutes, obtains fumigant disclosed by the invention.

Usage and dosage: get Medical gauze and cover on marmite, its disease smoked is picked up the ears hole and painful area 10-20 minute; Every day 2 ~ 3 times, every agent medicine 3 ~ 5 days, wind sheltering three days after smoked.

Embodiment 2:

One treats prosopalgic Chinese medicine composition, comprises the raw material of following weight:

Ramulus Mori 12g, Pheretima 12g, Rhizoma Paridis 12g, Caulis Piperis Kadsurae 12g, Caulis Trachelospermi 12g, Caulis Lonicerae 12g, Scolopendra 12g, Scorpio 12g, Cortex Acanthopancis 12g, Radix Curcumae 12g, Cortex Cinnamomi 12g, Rhizoma Chuanxiong 12g, Radix Paeoniae 12g, Radix Saposhnikoviae 12g, Radix Glycyrrhizae 10g, Semen Persicae 10g, Flos Carthami 10g, Radix Angelicae Sinensis 10g, Caulis Spatholobi 10g, Eupolyphaga Seu Steleophaga 10g.

Preparation and instructions of taking: with embodiment 1.

Embodiment 3:

One treats prosopalgic Chinese medicine composition, comprises the raw material of following weight:

Ramulus Mori 12g, Pheretima 12g, Rhizoma Paridis 12g, Caulis Piperis Kadsurae 12g, Caulis Trachelospermi 12g, Caulis Lonicerae 12g, Scolopendra 12g, Scorpio 12g, Cortex Acanthopancis 12g, Radix Curcumae 12g, Cortex Cinnamomi 12g, Rhizoma Chuanxiong 12g, Radix Paeoniae 12g, Radix Saposhnikoviae 12g, Radix Glycyrrhizae 10g, Radix Aconiti 10g, Ramulus Cinnamomi 10g, Herba Ephedrae 10g, Rhizoma Et Radix Notopterygii 10g, Herba Asari 10g, Herba Lycopodii 10g.

Preparation and instructions of taking: with embodiment 1.

Embodiment 4:

One treats prosopalgic Chinese medicine composition, comprises the raw material of following weight:

Ramulus Mori 12g, Pheretima 12g, Rhizoma Paridis 12g, Caulis Piperis Kadsurae 12g, Caulis Trachelospermi 12g, Caulis Lonicerae 12g, Scolopendra 12g, Scorpio 12g, Cortex Acanthopancis 12g, Radix Curcumae 12g, Cortex Cinnamomi 12g, Rhizoma Chuanxiong 12g, Radix Paeoniae 12g, Radix Saposhnikoviae 12g, Radix Glycyrrhizae 10g, Fructus Lycii 10g, Radix Rehmanniae 10g, Rhizoma Dioscoreae 10g, Fructus Corni 10g, Radix Adenophorae (Radix Glehniae) 10g.

Preparation and instructions of taking: with embodiment 1.

Embodiment 5:

One treats prosopalgic Chinese medicine composition, it is characterized in that, comprises the raw material of following weight:

Ramulus Mori 12g, Pheretima 12g, Rhizoma Paridis 12g, Caulis Piperis Kadsurae 12g, Caulis Trachelospermi 12g, Caulis Lonicerae 12g, Scolopendra 12g, Scorpio 12g, Cortex Acanthopancis 12g, Radix Curcumae 12g, Cortex Cinnamomi 12g, Rhizoma Chuanxiong 12g, Radix Paeoniae 12g, Radix Saposhnikoviae 12g, Radix Glycyrrhizae 10g, Rhizoma Gastrodiae 10g, Ramulus Uncariae Cum Uncis 10g, Concha Margaritifera 10g, Concha Haliotidis 10g.

Preparation and instructions of taking: with embodiment 1.

Embodiment 6: one treats prosopalgic Chinese medicine composition, comprises the raw material of following weight:

Ramulus Mori 12g, Pheretima 12g, Rhizoma Paridis 12g, Caulis Piperis Kadsurae 12g, Caulis Trachelospermi 12g, Caulis Lonicerae 12g, Scolopendra 12g, Scorpio 12g, Cortex Acanthopancis 12g, Radix Curcumae 12g, Cortex Cinnamomi 12g, Rhizoma Chuanxiong 12g, Radix Paeoniae 12g, Radix Saposhnikoviae 12g, Radix Glycyrrhizae 10g, Rhizoma Coptidis 10g, Flos Chrysanthemi 10g, Herba Dendrobii 10g, Fructus Viticis 10g

Preparation and instructions of taking: with embodiment 1.

Claims (9)

1. treat a prosopalgic Chinese medicine composition, it is characterized in that, comprise the raw material of following weight:

Ramulus Mori 12g, Pheretima 12g, Rhizoma Paridis 12g, Caulis Piperis Kadsurae 12g, Caulis Trachelospermi 12g, Caulis Lonicerae 12g, Scolopendra 12g, Scorpio 12g, Cortex Acanthopancis 12g, Radix Curcumae 12g, Cortex Cinnamomi 12g, Rhizoma Chuanxiong 12g, Radix Paeoniae 12g, Radix Saposhnikoviae 12g, Radix Glycyrrhizae 10g.

2. the prosopalgic Chinese medicine composition for the treatment of according to claim 1, is characterized in that, described Chinese medicine composition also comprises the raw material of following weight: Semen Persicae 10g, Flos Carthami 10g, Radix Angelicae Sinensis 10g, Caulis Spatholobi 10g, Eupolyphaga Seu Steleophaga 10g.

3. the prosopalgic Chinese medicine composition for the treatment of according to claim 1, is characterized in that, described Chinese medicine composition also comprises the raw material of following weight:

Radix Aconiti 10g, Ramulus Cinnamomi 10g, Herba Ephedrae 10g, Rhizoma Et Radix Notopterygii 10g, Herba Asari 10g, Herba Lycopodii 10g.

4. the prosopalgic Chinese medicine composition for the treatment of according to claim 1, is characterized in that, described Chinese medicine composition also comprises the raw material of following weight:

Fructus Lycii 10g, Radix Rehmanniae 10g, Rhizoma Dioscoreae 10g, Fructus Corni 10g, Radix Adenophorae (Radix Glehniae) 10g.

5. the prosopalgic Chinese medicine composition for the treatment of according to claim 1, is characterized in that, described Chinese medicine composition also comprises the raw material of following weight:

Rhizoma Gastrodiae 10g, Ramulus Uncariae Cum Uncis 10g, Concha Margaritifera 10g, Concha Haliotidis 10g.

6. the prosopalgic Chinese medicine composition for the treatment of according to claim 1, is characterized in that, described Chinese medicine composition also comprises the raw material of following weight:

Rhizoma Coptidis 10g, Flos Chrysanthemi 10g, Herba Dendrobii 10g, Fructus Viticis 10g.

7., according to the arbitrary described prosopalgic Chinese medicine composition for the treatment of of claim 1-6, it is characterized in that, the raw material described in claim 1-6 is made Oral preparation and fumigant; Described Oral preparation is medicated wine.

8. the prosopalgic Chinese medicine composition for the treatment of according to claim 7, is characterized in that, the preparation method of described medicated wine comprises the following steps:

1. the weight according to claim 1-6 takes raw material, raw material pulverizing to the 120 order fine powder then will taken;

2. needed raw material fine powder is all put into marmite, add water to and exceed powder 10 cm, soak about 4 hours, then heated and boiled 1 hour, after filtration, obtains medicinal liquid one;

3. the medicinal residues after step 2. middle filtration are added water again and decoct 1 time, after filtration again in right amount, obtain medicinal liquid two;

4. merge medicinal liquid one and medicinal liquid two, leave standstill after 6 hours, then get supernatant heating and be condensed into paste, be cooled to room temperature;

5. by step 4. in paste medicinal liquid be mixed into the Chinese liquor of equivalent spirituosity amount at 50%-60%, mix homogeneously, is placed in container, sealing, take out supernatant after about 7 days, obtain medicated wine disclosed by the invention.

9. the prosopalgic Chinese medicine composition for the treatment of according to claim 7, is characterized in that, the preparation method of described fumigant comprises the following steps:

(1) weight according to claim 1-6 takes raw material, raw material pulverizing to the 120 order fine powder then will taken;

(2) fine powder of step (1) is all put into marmite, add water to and exceed powder 10 cm, soak about 2 hours, then heated and boiled 5 minutes, obtains fumigant disclosed by the invention.