CN104645079A - Traditional Chinese medicine for treating post-stroke limb numbness - Google Patents

Traditional Chinese medicine for treating post-stroke limb numbness Download PDF

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CN104645079A
CN104645079A CN201510045870.5A CN201510045870A CN104645079A CN 104645079 A CN104645079 A CN 104645079A CN 201510045870 A CN201510045870 A CN 201510045870A CN 104645079 A CN104645079 A CN 104645079A
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崔合芳
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Abstract

The invention discloses a traditional Chinese medicine for treating post-stroke limb numbness, relating to the technical field of traditional Chinese medicines. The traditional Chinese medicine comprises the 19 raw materials including semen brassicae, rhizoma atractylodis, gastrodia elata, mucuna macrocarpa wallich, radix scrophulariae, Chinese angelica, phyllanthus urinaria, papaya, the root of bidentate achyranthes, astragalus membranaceus, notopterygium root, common andrographis herb, lumbricus, gynostemma pentaphylla, bracketplant, root of rustyhair raspberry, ptyas mucosus, lactarius lignyotus and honey-fried licorice root. The traditional Chinese medicine disclosed by the invention has the good curative effect to post-stroke limb numbness; and furthermore, the traditional Chinese medicine is simple in preparation process, steady in preparation and easy to popularization and application.

Description

A kind of Chinese medicine for the treatment of numb limbs and tense tendons after apoplexy
Technical field
The invention belongs to technical field of Chinese medicines, be specifically related to a kind of Chinese medicine for the treatment of numb limbs and tense tendons after apoplexy.
Background technology
Apoplexy is one group of disease being main clinical manifestation with cerebral ischemic and heamorrhagic lesions symptom, also known as apoplexy or cerebrovas-cularaccident, there is high case fatality rate and disability rate, mainly be divided into hemorrhagic cerebral apoplexy (cerebral hemorrhage or subarachnoid hemorrhage) and the large class of ischemia apoplexy (cerebral infarction, cerebral thrombosis) two, the most common with cerebral infarction.Apoplexy morbidity is anxious, and case fatality rate is high, and be one of the most serious in the world fatal disease, even if treatment in time, each histoorgan of health also has damage in various degree, and numb limbs and tense tendons is exactly the symptom after its sensory nerve maincenter and related neural fibre damage.
At present, the medicine for the treatment of apoplexy sequela is numerous, wherein also has some to can be used for treating the medicine of numb limbs and tense tendons, as aspirin, FUFANG DANSHEN DIWAN etc., but curative effect is general mostly, and side effect is large, be difficult in short time take effect, easily hit the self-confidence of patient, make patient produce mental pressure.The present invention is directed to the cause of disease focus that apoplexy causes numb limbs and tense tendons, Symptomatic medicine, repair damaged nerve fibers, have studied a kind of Chinese medicine for the treatment of numb limbs and tense tendons after apoplexy, patient takes medicine of the present invention can quick-recovery limbs normal function soon in conjunction with self taking exercise.
Summary of the invention
Technical problem to be solved by this invention is, provide a kind of can the Chinese medicine composition of numb limbs and tense tendons after safe and effective treatment apoplexy.
Inventor's foundation tcm clinical practice experience for many years and the ill feature of modern, provide a kind of Chinese medicine composition for the treatment of numb limbs and tense tendons after apoplexy, be prepared from by the Chinese crude drug of following weight portion: Semen Sinapis Albae 18-22 part, Rhizoma Atractylodis 15-18 part, Rhizoma Gastrodiae 15-18 part, Caulis seu Radix Schisandrae Henryi 10-15 part, Radix Scrophulariae 10-15 part, Radix Angelicae Sinensis 15-18 part, one leaf Miscanthus sacchariflorus (Maxim) Benth et Hook f 10-15 part, Fructus Caricae 18-22 part, Radix Achyranthis Bidentatae 15-18 part, Radix Astragali 10-15 part, Rhizoma Et Radix Notopterygii 10-15 part, Herba Andrographis 18-22 part, Pheretima 18-22 part, Herb Gynostemmae Pentaphylli 20-24 part, Cornu Draconis Fossilia grass 15-18 part, Radix Rubi reflexi 15-18 part, mouse Serpentis 8-12 part, black newborn mushroom 18-22 part, Radix Glycyrrhizae Preparata 25-28 part.
Grope in process in clinical practice, find that following 2 proportioning effects are best, be respectively:
Proportioning 1: Semen Sinapis Albae 20 parts, Rhizoma Atractylodis 16 parts, 17 parts, Rhizoma Gastrodiae, Caulis seu Radix Schisandrae Henryi 14 parts, Radix Scrophulariae 13 parts, Radix Angelicae Sinensis 16 parts, leaf Miscanthus sacchariflorus (Maxim) Benth et Hook f 12 parts, Fructus Caricae 20 parts, Radix Achyranthis Bidentatae 16 parts, the Radix Astragali 14 parts, Rhizoma Et Radix Notopterygii 14 parts, Herba Andrographis 20 parts, Pheretima 21 parts, Herb Gynostemmae Pentaphylli 21 parts, Cornu Draconis Fossilia grass 17 parts, Radix Rubi reflexi 17 parts, mouse Serpentis 10 parts, black 20 parts, newborn mushroom, Radix Glycyrrhizae Preparata 26 parts.
Proportioning 2: Semen Sinapis Albae 20 parts, Rhizoma Atractylodis 17 parts, 18 parts, Rhizoma Gastrodiae, Caulis seu Radix Schisandrae Henryi 12 parts, Radix Scrophulariae 12 parts, Radix Angelicae Sinensis 18 parts, leaf Miscanthus sacchariflorus (Maxim) Benth et Hook f 14 parts, Fructus Caricae 21 parts, Radix Achyranthis Bidentatae 17 parts, the Radix Astragali 13 parts, Rhizoma Et Radix Notopterygii 13 parts, Herba Andrographis 19 parts, Pheretima 20 parts, Herb Gynostemmae Pentaphylli 22 parts, Cornu Draconis Fossilia grass 16 parts, Radix Rubi reflexi 16 parts, mouse Serpentis 11 parts, black 21 parts, newborn mushroom, Radix Glycyrrhizae Preparata 27 parts.
People is for solving the problems of the technologies described above in invention, and also invented the preparation technology being made by Chinese prescription of the present invention and facilitate easy-to-use Chinese medicine finished product preparation, step is as follows:
Take each taste Chinese crude drug by Chinese medicine proportioning of the present invention, put into container, first time adds 8-11 times amount distilled water immersion 5-10 hour, and backflow decocts 2-4 hour, filters; Second time adds the backflow of initial medical material weight 5-8 times amount distilled water and decocts 1-3 hour, filters; Merge twice filtrate, filtrate is condensed into Chinese medical concrete, add the form of Chinese drug that clinical needs made by adjuvant, as tablet, pill, granule, capsule, powder, syrup etc.
The source of the present invention's Chinese crude drug used, feature, meridian distribution of property and flavor and effect:
Semen Sinapis Albae: promoting the circulation of QI eliminating phlegm, warming spleen and stomach for dispelling cold, removing obstruction in the collateral to relieve pain.Control phlegm retention cough with asthma, fullness and distention in the chest and hypochondrium pain, regurgitation is vomitted, aphasia due to apoplexy, and limbs arthralgia pain is numb, beriberi, carbuncle of yin nature, toxic swelling, treating swelling and pain by traumatic injury.Select the seed of crucifer Caulis et Folium Sinapis albee.
Rhizoma Atractylodis: drying damp and strengthening spleen, expelling wind and cold, improving eyesight.Cure mainly wet Sheng and be stranded spleen, asthenia drowsiness, gastral cavity painful abdominal mass abdominal distention, inappetence, vomiting, has loose bowels, dysentery, malaria, phlegm retention, edema, and seasonal epidemic pathogens is caught a cold, and podomere is ached and weighed, anemofrigid-damp arthralgia, flaccidity of the lower limbs, nyctalopia.Select the dry rhizome of Compositae herbaceos perennial Atractylodes lancea (Thunb.) DC. or Atractylis chinensis.
Rhizoma Gastrodiae: suppressing the hyperactive liver to relieve the wind syndrome, wind-expelling pain-stopping, has calmness, analgesia, anticonvulsant action; Can cerebral blood flow be increased, reduce cerebral vascular resistance, light contraction cerebrovascular, increase coronary vasodilator flow; Can reduce blood pressure, decreased heart rate, has protective effect to myocardial ischemia; .The headache of blood deficiency liver-wind stirring up internally, dizzy, dizzy, migraine and general headache, numb limbs and tense tendons, hemiplegia that wind-phlegm causes can be treated.Also can be used for infantile convulsion, epilepsy, tetanus.Select the dry tuber of the orchid family Gastrodia plant.
Caulis seu Radix Schisandrae Henryi: nourish blood repercussive, regulating QI to expel dampness.Control consumptive disease wound to spit blood, podomere ache, heart peratodynia, beriberi flaccidity syndrome and arthralgia syndrome, menoxenia, traumatic injury.Select rattan or the root of Magnoliacea plant schisandra henryi Clarke or schisandra chinensis.
Radix Scrophulariae: removing heat from blood YIN nourishing, eliminating fire and detoxication.Cure mainly: warm febrile disease and nutrient blood, fever of the body, excessive thirst, crimson tongue, send out speckle, hectic fever due to YIN-deficiency chronic cough, fidgets due to deficiency not awake, Tianjin hinder constipation, order puckery dim-sighted, throat larynx swells and ache, scrofula sucutaneous nodule, skin sore.Select the dry root of goatweed Radix Scrophulariae.
Radix Angelicae Sinensis: hematonic; Enrich blood, invigorate blood circulation, menstruction regulating and pain relieving, moisturize laxation, cure mainly all cards of blood deficiency; Menoxenia; Amenorrhea; Dysmenorrhea; Lump in the abdomen knot is poly-; Metrorrhagia; Asthenia cold abdominalgia; Flaccidity syndrome and arthralgia syndrome; Numbness of the skin; Dryness of the intestine dyschezia; Heavy after bloody dysentery; Ulcer sores; Injury from falling down.Select the dry root of umbelliferae angelica.
One leaf Miscanthus sacchariflorus (Maxim) Benth et Hook f: relaxing muscles and tendons to promote blood circulation, tonifying speen and tonifying kidney.Dispelling the wind and dampness pathogens lumbago, numb limbs and tense tendons, hemiplegia, sexual impotence, facial paralysis, poliomyelitis sequela.Select browse and the root of euphorbia plant one leaf Miscanthus sacchariflorus (Maxim) Benth et Hook f.
Fructus Caricae: invigorating the stomach and promoting digestion, nourishing lactogenic, channels sootheing and network vessel quickening.For weakness of the spleen and stomach, inappetence, hypogalactia, Fengshi Guanjie pain, numb limbs and tense tendons, taste-blindness rate pain.Select Caricaceae Fructus Caricae platymiscium Fructus Caricae with fruit medicine.
Radix Achyranthis Bidentatae: invigorating the liver and kidney; Bone and muscle strengthening; Promoting blood circulation to restore menstrual flow; Ignite (blood) descending; Inducing diuresis for treating stranguria syndrome.Cure mainly soreness of waist and knee joint; Flaccidity and weakness of the lower limbs; Amenorrhea due to stagnation of blood; Dysmenorrhea; Puerperal abdominal pain due to blood stasis; Lump in the abdomen; Retention of placenta; Pyretic stranguria; Stranguria with blood; Traumatic injury; Carbuncle malignant boil; Laryngopharynx swelling and pain.Select the root of amaranthaceous plant Radix Achyranthis Bidentatae.
The Radix Astragali: there is invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, effect of expelling pus and promoting granulation.Weak for the deficiency of vital energy, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, carbuncle difficulty is burst, and burst for a long time and do not hold back, blood deficiency and yellow complexion, interior-heat is quenched one's thirst.Select the dry root of leguminous plant Radix Astagali or Radix Astragali.
Rhizoma Et Radix Notopterygii: cold expelling, dispels the wind, dehumidifying, pain relieving.For anemofrigid cold headache, rheumatic arthralgia, aching pain in should and back.Select dry rhizome and the root of samphire Rhizoma Et Radix Notopterygii (back of the body wing celery) or Radix et Rhizoma Notopterygii.
Herba Andrographis: heat-clearing and toxic substances removing, removing heat from blood is subsided a swelling.Control acute bacillary dysentery, gastroenteritis, flu, epidemic encephalitis, tracheitis, pneumonia, pertussis, pulmonary tuberculosis, lung abscess, cholecystitis, hypertension, epistaxis, oropharynx swells and ache, furuncle carbuncle, burn due to hot liquid or fire, venom.Select the dry aerial parts of acanthaceous plant Herba Andrographis (circular cone palpus medicinal herbs).
Radix Rubi reflexi: expelling wind and removing dampness, promoting blood circulation to remove obstruction in the collateral.Main anemofrigid-damp arthralgia, membra arthralgia, apoplectic hemiplegia, numb limbs and tense tendons, moving obstacle.Select the root of rosaceous plant Radix Rubi reflexi.
Mouse Serpentis: wind-expelling pain-stopping; Channels sootheing and network vessel quickening.Main air arthralgia chiefly caused by damp pathogen is demonstrate,proved; Numb limbs and tense tendons; Paralysis.Colubridae animal mouse Serpentis is selected to remove the entirety of internal organs.
Black newborn mushroom: expelling wind and cold; Relaxing muscles and tendons and activating QI and blood in the collateral.Main air pain of dampness syndrome; Numb limbs and tense tendons; Tetany.Select the sporophore of Russulaceae fungus drop blue milk mushroom.
Radix Glycyrrhizae Preparata: spleen reinforcing stomach function regulating, Yiqi and vein recovery.For weakness of the spleen and stomach, fatigue and weakness, severe palpitation, irregularly intermittent and regularly intermittent pulse.Selecting the Preparation process product of Radix Glycyrrhizae, is similar round or oval section, and the brown or taupe brown of surface red, micro-glossy, tangent plane is yellow to buff, and cambium ring is obvious, ray irradiation shape.Matter is slightly glutinous.Tool burnt odor gas, taste is sweet.
Chinese medicine composition of the present invention is natural pure Chinese medicinal preparation, and each component is coordinated mutually, combined effect, can Yiqi and vein recovery, wind-expelling pain-stopping, channels sootheing and network vessel quickening, thus has good therapeutic effect to apoplexy hind leg body numbness; The preparation technology of Chinese medicine composition of the present invention is simple to operation, has no adverse reaction, and side effect is little, patient medication safety.
Detailed description of the invention
Embodiment 1
(1) each taste Chinese crude drug is taken: Semen Sinapis Albae 20 parts, Rhizoma Atractylodis 16 parts, 17 parts, Rhizoma Gastrodiae, Caulis seu Radix Schisandrae Henryi 14 parts, Radix Scrophulariae 13 parts, Radix Angelicae Sinensis 16 parts, leaf Miscanthus sacchariflorus (Maxim) Benth et Hook f 12 parts, Fructus Caricae 20 parts, Radix Achyranthis Bidentatae 16 parts, the Radix Astragali 14 parts, Rhizoma Et Radix Notopterygii 14 parts, Herba Andrographis 20 parts, Pheretima 21 parts, Herb Gynostemmae Pentaphylli 21 parts, Cornu Draconis Fossilia grass 17 parts, Radix Rubi reflexi 17 parts, mouse Serpentis 10 parts, black 20 parts, newborn mushroom, Radix Glycyrrhizae Preparata 26 parts;
(2) get above-mentioned weight portion medical material and put into container, first time adds 10 times amount distilled water immersion 8 hours, and backflow decoction 3 hours, filters; Second time adds initial medical material weight 6 times amount distilled water backflow decoction 2 hours, filters; Merge twice filtrate, filtrate is condensed into Chinese medical concrete, add adjuvant and make clinical granule, amount to crude drug content and be about 0.24g crude drug/g granule.
Embodiment 2
(1) each taste Chinese crude drug is taken: Semen Sinapis Albae 20 parts, Rhizoma Atractylodis 17 parts, 18 parts, Rhizoma Gastrodiae, Caulis seu Radix Schisandrae Henryi 12 parts, Radix Scrophulariae 12 parts, Radix Angelicae Sinensis 18 parts, leaf Miscanthus sacchariflorus (Maxim) Benth et Hook f 14 parts, Fructus Caricae 21 parts, Radix Achyranthis Bidentatae 17 parts, the Radix Astragali 13 parts, Rhizoma Et Radix Notopterygii 13 parts, Herba Andrographis 19 parts, Pheretima 20 parts, Herb Gynostemmae Pentaphylli 22 parts, Cornu Draconis Fossilia grass 16 parts, Radix Rubi reflexi 16 parts, mouse Serpentis 11 parts, black 21 parts, newborn mushroom, Radix Glycyrrhizae Preparata 27 parts;
(2) get above-mentioned weight portion medical material and put into container, first time adds 9 times amount distilled water immersion 6 hours, and backflow decoction 4 hours, filters; Second time adds initial medical material weight 7 times amount distilled water backflow decoction 1.5 hours, filters; Merge twice filtrate, filtrate is condensed into Chinese medical concrete, add adjuvant and make clinical granule, amount to crude drug content and be about 0.24g crude drug/g granule.
Embodiment 3
(1) each taste Chinese crude drug is taken: Semen Sinapis Albae 18 parts, Rhizoma Atractylodis 15 parts, 15 parts, Rhizoma Gastrodiae, Caulis seu Radix Schisandrae Henryi 10 parts, Radix Scrophulariae 10 parts, Radix Angelicae Sinensis 15 parts, leaf Miscanthus sacchariflorus (Maxim) Benth et Hook f 10 parts, Fructus Caricae 18 parts, Radix Achyranthis Bidentatae 15 parts, the Radix Astragali 10 parts, Rhizoma Et Radix Notopterygii 10 parts, Herba Andrographis 18 parts, Pheretima 18 parts, Herb Gynostemmae Pentaphylli 20 parts, Cornu Draconis Fossilia grass 15 parts, Radix Rubi reflexi 15 parts, mouse Serpentis 8 parts, black 18 parts, newborn mushroom, Radix Glycyrrhizae Preparata 25 parts;
(2) get above-mentioned weight portion medical material and put into container, first time adds 11 times amount distilled water immersion 8 hours, and backflow decoction 4 hours, filters; Second time adds initial medical material weight 8 times amount distilled water backflow decoction 2 hours, filters; Merge twice filtrate, filtrate is condensed into Chinese medical concrete, add adjuvant and make clinical granule, amount to crude drug content and be about 0.24g crude drug/g granule.
Embodiment 4
(1) each taste Chinese crude drug is taken: Semen Sinapis Albae 22 parts, Rhizoma Atractylodis 18 parts, 18 parts, Rhizoma Gastrodiae, Caulis seu Radix Schisandrae Henryi 15 parts, Radix Scrophulariae 15 parts, Radix Angelicae Sinensis 18 parts, leaf Miscanthus sacchariflorus (Maxim) Benth et Hook f 15 parts, Fructus Caricae 22 parts, Radix Achyranthis Bidentatae 18 parts, the Radix Astragali 15 parts, Rhizoma Et Radix Notopterygii 15 parts, Herba Andrographis 22 parts, Pheretima 22 parts, Herb Gynostemmae Pentaphylli 24 parts, Cornu Draconis Fossilia grass 18 parts, Radix Rubi reflexi 18 parts, mouse Serpentis 12 parts, black 22 parts, newborn mushroom, Radix Glycyrrhizae Preparata 28 parts;
(2) get above-mentioned weight portion medical material and put into container, first time adds 8 times amount distilled water immersion 5 hours, and backflow decoction 2 hours, filters; Second time adds initial medical material weight 5 times amount distilled water backflow decoction 3 hours, filters; Merge twice filtrate, filtrate is condensed into Chinese medical concrete, add adjuvant and make clinical granule, amount to crude drug content and be about 0.24g crude drug/g granule.
The animal toxicity test of embodiment 5 Chinese medicine granules of the present invention
(1) test drug: Chinese medicine granules obtained by embodiment of the present invention 1-4, is modulated into solution by purified water by 1:1.Test animal used: regular grade NIH mice, body weight 21g ± 5g, male and female half and half, female mice is all without pregnant; SD rat, original body mass 215g ± 7g, male and female half and half, female rats is all without pregnant.
(2) acute toxicity test
Application mice carries out acute toxicity testing and shows: the By Chinese Medicines that mouse stomach modulates, under 759.6g crude drug/kg dosage, after administration, mice occurs that light activity reduces, 1 hours recovers normal, Continuous Observation 7 days after administration, none dead mouse, and overall health of patients, diet, take the photograph water, urine and body weight increase all normal.Experimental result shows: the maximum dosage-feeding of mouse stomach Chinese medicine granules of the present invention is 759.6g crude drug/kg/d(LD50 > 759.6g crude drug/kg).Chinese medicine preparation clinical application every day total amount of the present invention is 0.12g crude drug/kg/d; By weighing machine, the dosis tolerata of mouse stomach Chinese medicine preparation of the present invention is 6330 times of clinical patient.Point out this medicine acute toxicity extremely low, clinical drug safety.
(3) long term toxicity test
Select SD rat, give the Chinese medicine granules of the present invention of Three doses: 21.6g crude drug/kg, 7.2g crude drug/kg, 2.4g crude drug/kg(per weight dosage is by 20 times of calculating of clinical application amount, and clinical application amount is according to Pharmacopoeia of the People's Republic of China version in 2010).Every day gavage once, continuous 90 days, after last administration 24 hours respectively group live and kill 1/2 animal (male and female half and half), all the other 1/2 animals continue that observations are alive after 2 weeks kills.Duration of test observes outward appearance, general behavior, food ration, the body weight change of animal; Within after administration 90 days, within 2 weeks, carry out the index checking such as hematology's (RBC, HB, reticulocyte, PLT, CT, WBC and classification) and blood biochemical (AST, ALT, ALP, Glu, BUN, Crea, TP, T.BIL, ALB, CHOL), urine biochemistry, organ coefficient, histopathology with drug withdrawal.
Result of the test shows: Chinese medicine preparation of the present invention is good at high, medium and low dosage treated animal general state, and outward appearance sign, behavioral activity, food-intake and body weight increase change all without exception; Three dosage groups and matched group hematological examination, blood biochemical analysis, urine biochemical analysis all in normal range, without significant difference between group; Each group of main organs histopathological examination shows no obvious abnormalities.These parameters drug withdrawal also had no change after 2 weeks.This test dosage is respectively 180,60,20 times of clinical medicine dose, according to result of the test: Chinese medicine preparation of the present invention has no significant effect rat in high, medium and low three dosage (21.6g crude drug/kg, 7.2g crude drug/kg, 2.4g crude drug/kg) administration in continuous 90 days, without clear and definite toxicity target organ and sensitive indicator, convalescent period observation also has no retardance toxic reaction, points out the dose safety of Chinese medicine preparation clinical practice of the present invention very high.
Embodiment 6, clinical effectiveness are tested
1, experimenter's data
Numb limbs and tense tendons patient after the apoplexy that experimenter all accepts for medical treatment from certain the People's Hospital of city year February in June, 2012 to 2014, therefrom selects patient 123 example being applicable to test, wherein man 52 example, age 37-69 year, female 71 example, age 43-72 year.Patients is: extremity or side numb limbs and tense tendons, and numb to finger tip and shank to toe-end position based on forearm, myodynamia goes down, movable unfavorable or completely stiff.According to ill weight, age, sex, experimenter is divided into 3 groups, is numbered matched group respectively, test 1 group, test 2 groups, often organize 41 people.
2, test method
(1) matched group takes Ruanmailing oral liquid (the new Wuyi pharmaceutical Co. Ltd in Fujian, the accurate word Z35020207 of traditional Chinese medicines), each 15 milliliters, every day 2 times.
(2) test 1 group, test 2 groups of Chinese medicinal granules taken respectively obtained by the embodiment of the present invention 1,2, every day 2 times, it is 3.6g that each 15g(amounts to crude drug).
Within (3) 4 weeks, be a course for the treatment of, treat 6 courses for the treatment of continuously.In therapeutic process, cured person can depart from treatment at any time, simultaneously the situation such as health, untoward reaction of record patient.After six months return visit is followed the tracks of to healing person, record recidivist.
3, evaluation criterion
(1) cure: numb limbs and tense tendons symptom disappears completely, myodynamia recovers, can be freely movable;
(2) effective: numb limbs and tense tendons symptom partial disappearance, myodynamia increases, can be movable among a small circle; Still need continual cure;
(3) invalid: numb limbs and tense tendons symptom is without any improvement;
(4) untoward reaction: occur the discomforts such as stomachache, dizziness, Nausea and vomiting after taking medicine;
(5) recur: cure in latter 6 months and occur again same symptom.
4, result of the test statistical analysis
After test all terminates, statistical analysis is carried out, in table 1 to test data sheet data.
Table 1 result of the test statistical analysis table
5, conclusion (of pressure testing)
As can be seen from the test results, not there is untoward reaction in the patient taking Chinese medicine preparation of the present invention; The average cure rate (69.5%) of medicine of the present invention is 1.8 times of matched group, and average total effective rate (96.4%) is higher than matched group by 23.2%, and more after not easily recur.Therefore, as can be seen from these data, the Chinese medicine preparation of the present invention preparation that particularly prepared by embodiment 1, embodiment 2 has very significant technical advantage, obtains beat all technological achievement.

Claims (5)

1. treat a Chinese medicine for numb limbs and tense tendons after apoplexy, it is characterized in that being prepared from by the Chinese crude drug of following weight portion: Semen Sinapis Albae 18-22 part, Rhizoma Atractylodis 15-18 part, Rhizoma Gastrodiae 15-18 part, Caulis seu Radix Schisandrae Henryi 10-15 part, Radix Scrophulariae 10-15 part, Radix Angelicae Sinensis 15-18 part, leaf Miscanthus sacchariflorus (Maxim) Benth et Hook f 10-15 part, Fructus Caricae 18-22 part, Radix Achyranthis Bidentatae 15-18 part, Radix Astragali 10-15 part, Rhizoma Et Radix Notopterygii 10-15 part, Herba Andrographis 18-22 part, Pheretima 18-22 part, Herb Gynostemmae Pentaphylli 20-24 part, Cornu Draconis Fossilia grass 15-18 part, Radix Rubi reflexi 15-18 part, mouse Serpentis 8-12 part, black newborn mushroom 18-22 part, Radix Glycyrrhizae Preparata 25-28 part.
2. treat the Chinese medicine of numb limbs and tense tendons after apoplexy according to claim 1, it is characterized in that being prepared from by the Chinese crude drug of following weight portion: Semen Sinapis Albae 20 parts, Rhizoma Atractylodis 16 parts, 17 parts, Rhizoma Gastrodiae, Caulis seu Radix Schisandrae Henryi 14 parts, Radix Scrophulariae 13 parts, Radix Angelicae Sinensis 16 parts, leaf Miscanthus sacchariflorus (Maxim) Benth et Hook f 12 parts, Fructus Caricae 20 parts, Radix Achyranthis Bidentatae 16 parts, the Radix Astragali 14 parts, Rhizoma Et Radix Notopterygii 14 parts, Herba Andrographis 20 parts, Pheretima 21 parts, Herb Gynostemmae Pentaphylli 21 parts, Cornu Draconis Fossilia grass 17 parts, Radix Rubi reflexi 17 parts, mouse Serpentis 10 parts, black 20 parts, newborn mushroom, Radix Glycyrrhizae Preparata 26 parts.
3. treat the Chinese medicine of numb limbs and tense tendons after apoplexy according to claim 1, it is characterized in that being prepared from by the Chinese crude drug of following weight portion: Semen Sinapis Albae 20 parts, Rhizoma Atractylodis 17 parts, 18 parts, Rhizoma Gastrodiae, Caulis seu Radix Schisandrae Henryi 12 parts, Radix Scrophulariae 12 parts, Radix Angelicae Sinensis 18 parts, leaf Miscanthus sacchariflorus (Maxim) Benth et Hook f 14 parts, Fructus Caricae 21 parts, Radix Achyranthis Bidentatae 17 parts, the Radix Astragali 13 parts, Rhizoma Et Radix Notopterygii 13 parts, Herba Andrographis 19 parts, Pheretima 20 parts, Herb Gynostemmae Pentaphylli 22 parts, Cornu Draconis Fossilia grass 16 parts, Radix Rubi reflexi 16 parts, mouse Serpentis 11 parts, black 21 parts, newborn mushroom, Radix Glycyrrhizae Preparata 27 parts.
4. one kind prepare as arbitrary in claim 1-3 as described in the method for Chinese medicine of numb limbs and tense tendons after treatment apoplexy, it is characterized in that comprising following processing step: take each taste Chinese crude drug, put into container, first time adds 8-11 times amount distilled water immersion 5-10 hour, backflow decocts 2-4 hour, filters; Second time adds the backflow of initial medical material weight 5-8 times amount distilled water and decocts 1-3 hour, filters; Merge twice filtrate, filtrate is condensed into Chinese medical concrete, add the form of Chinese drug that clinical needs made by adjuvant.
5. the application of Chinese medicine after preparation treatment apoplexy in numb limbs and tense tendons medicine of numb limbs and tense tendons after the arbitrary described treatment apoplexy of claim 1-3.
CN201510045870.5A 2015-01-29 2015-01-29 Traditional Chinese medicine for treating post-stroke limb numbness Withdrawn CN104645079A (en)

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CN106138410A (en) * 2016-08-12 2016-11-23 泰山医学院附属医院 Chinese medicine composition and the device for fumigation of numb limbs and tense tendons after apoplexy is treated based on stifling mode

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CN103156934A (en) * 2011-12-12 2013-06-19 廖凤武 Traditional Chinese medicine for treating apoplexy sequela

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106138410A (en) * 2016-08-12 2016-11-23 泰山医学院附属医院 Chinese medicine composition and the device for fumigation of numb limbs and tense tendons after apoplexy is treated based on stifling mode

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