CN105213721A - A kind of Chinese medicine preparation for the treatment of gastroptosis - Google Patents
A kind of Chinese medicine preparation for the treatment of gastroptosis Download PDFInfo
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Abstract
The invention discloses a kind of Chinese medicine preparation for the treatment of gastroptosis, belong to technical field of Chinese medicines.This Chinese medicine preparation is processed by following raw material: Fructus Evodiae, the Radix Astragali, Radix Codonopsis, Flos Inulae, Ramulus Cinnamomi, Endothelium Corneum Gigeriae Galli, Rhizoma Dioscoreae, Herba Taraxaci, Rhizoma Cimicifugae, Fructus Aurantii, Poria, Rhizoma Atractylodis, Fructus Psoraleae, fresh pomegranate rind, Radix Glycyrrhizae.This Chinese medicine preparation in treatment gastroptosis, compared with prior art, have instant effect, therapeutic effect good, more after do not recur, have no side effect; And its preparation process is simple and easy to do, cost is low, preparation efficacy stability, universality are good, are applicable to suitability for industrialized production.
Description
Technical field
The invention belongs to technical field of Chinese medicines, relate to a kind of Chinese medicine preparation for the treatment of gastroptosis.
Background technology
Gastroptosis is because diaphram hangs power deficiency, supports internal organs laxity of ligament, or intra-abdominal pressure reduces, and abdominal muscle relaxes, and when causing standing, greater gastric curvature arrives at pelvic cavity, and lesser gastric curvature camber line minimum point drops to below crista iliaca on line.Often with the change of duodenal bulb position.
The Therapeutic Method that current doctor trained in Western medicine is taked is: epigastric discomfort, dull pain, dyspepsia etc. can refer to chronic gastritis treatment; The slow person of abdominal distention, gastric emptying, can supply motilium or metoclopramide; Merge the first-selected mosapride sheet of constipation person; ATP treatment on probation, morning every day, intramuscular injection half an hour in ante prandium, within 25th, be 1 course for the treatment of, second course for the treatment of is carried out after 5 days again in interval; Place stomacher if desired.These methods mostly are cures the symptoms, not the disease, and side effect is large, and the misery caused to patient is large.
Gastroptosis is equivalent to " stomach delays " of Chinese medicine, and this title, head sees Huangdi's Internal Classics." this Tibetan of Ling Shu Miraculous Pivot or Divine Axis " section cloud: " spleen answers meat ... under the not fit person's stomach of meat trunk, person under stomach, lower pipe is about unfavorable.The not hard person of meat rouge, stomach delays." to explicitly point out muscle thin and weak on the lower side with the position of the disproportionate stomach of figure, the solid not then stomach of muscle delays." its people's element is contained modern thin, and water is walked between intestinal, and the sound of wind or of flowing waters is sound, the phlegm retention of meaning " described in " Medical Treasures of the Golden Chamber ", the symptom of quite similar primary disease.In successive dynasties doctor nationality, though do not discussed slow for stomach as special disease, during many diseases about taste visceral dysfunction refer, relate to the symptom of gastroptosis, as abdominal distention, feeling of fullness, belch etc. more.
The suggestion of comprehensive doctor at all times, the cause of disease of gastroptosis divides nature and nurture two class.Congenital factors is that natural endowment is weak, body constitution virtual loss; The day after tomorrow then can be summarized as drinking and eating irregularly, and too much, seven emotions are indisposed for prolonged illness or delivery and feed infant.Its sick position is at taste, and main pathogenesis can be summarized as void, the stasis of blood two word, and based on void.
Gas (sun) is empty or lose because natural endowment is plain, and worry impairing spleen, causes sinking of QI due to deficiency of the spleen, strong fortune mistake department, and muscle is not hard, stomach internal organs loses admittedly sagging, or because of the ferritic deficiency of YIN, hinders footpath between fields addicted to tea polydipsia, the cold and cool impairment of the spleen of surfeit, causes middle burnt disorder in ascending and descending, water Tianjin is stagnated, and turns to phlegm retention, and QI and blood is without life, and muscles along the regular meridians loses foster and sagging.
The multifactor body yang deficiency of the deficiency of YIN, or prolonged illness fecund is educated and injured cloudy blood, burn in five ambition fire, cause deficiency of stomach-Yin, the muscle arteries and veins of stomach loses in making moist, and slowly vertically not to receive, and causes gastroptosis.
Following 5 kinds of typings can be summarized as.
1, yang deficiency drink stops
Disease sees that gastral cavity abdomen falling inflation is not relaxed, after food very, desire for warm and being pressed, palpitation moves, and gastric shakes, and to walk rumbling between intestinal sound for the underwater sound or water, or vomiting and nausea clear water sputum, or doublely to have a dizzy spell, loose stool, light red tongue is fat indentation, white, slippery and moist fur, stringy and rolling pulse or stringy and thready pulse.Control suitable warming yang for resolving fluid retention, regulating the stomach and sending down the abnormal ascending QI.
2, sinking of QI due to deficiency of the spleen
Disease sees that ferritic is weak, gastral cavity abdomen falling inflation, after food, stands or tired postemphasis, poor appetite lack of appetite, shallow complexion, fatigue and weakness, light red tongue or have indentation, white and thin fur, thready pulse or slow.Control and should QI invigorating rise sunken, invigorating the spleen and regulating the stomach.
3, stomach network stasis blocking
Be more common in the course of disease longer or chronic disease companion gastroptosis person.Its disease chest and diaphragm feeling of fullness, gastral cavity abdomen falling inflation pain, aching as needle stabbing, fixes and does not move, and eat rear or becoming severe at night, but feeling soft in the abdomen while pressing is soft, shape is thin, dim complexion, or has hematemesis, melena, and tongue is dark or have ecchymosis, thin fur, deep-thready pulse or puckery.Controlling should blood circulation promoting and blood stasis dispelling, soothing the liverly nourishes blood.
4, deficiency of stomach-Yin
Disease sees that gastral cavilty feeling of fullness is scorching hot, and indistinctly make pendant pain, hunger but having no desire to eat, dryness of the mouth and throat, excessive thirst and desire for drinking, vomiting and nausea is indigestion and loss of appetite, and body constitution is partially thin, defecates partially dry, red tongue with a little fluid or have crackle, the few or no fur of tongue, thready and rapid pulse.Control suitable nourishing stomach-YIN, regulating the stomach and sending down the abnormal ascending QI.
5, incoordination between the liver and stomach
Disease sees the swollen pain of gastral cavilty painful abdominal mass, very then connects and two sides of body, and singultus, belch are frequent, after food more so, and sighing frequently, or noisy acid, thin white fur of tongue or greasy in vain, stringy and thready pulse.Control suitable dispersing the stagnated liver-QI for regulating the stomach, harmonizing the functional activities of vital QI.
Summary of the invention
The technical problem to be solved in the present invention is that invention one treats the good Chinese medicine preparation of gastroptosis effect.For solving this technical problem, the technical scheme that inventor takes is, first according to Chinese medical theory to the dialectical cognition of gastroptosis, in conjunction with the experience of practising medicine of self, invent a new Chinese prescription; Then according to the effect of clinical practice and the feature of modern Chinese medicine preparation process, repeatedly adjust the kind of prescription medical material and ratio and grope, finally invented a brand-new Chinese prescription, the Chinese medicine preparation be made up of this prescription is evident in efficacy to gastroptosis.This Chinese prescription is (with parts by weight):
Fructus Evodiae 7-28 part, Radix Astragali 7-34 part, Radix Codonopsis 8-40 part, Flos Inulae 7-29 part, Ramulus Cinnamomi 6-16 part, Endothelium Corneum Gigeriae Galli 6-22 part, Rhizoma Dioscoreae 6-26 part, Herba Taraxaci 6-20 part, Rhizoma Cimicifugae 6-19 part, Fructus Aurantii 6-18 part, Poria 7-30 part, Rhizoma Atractylodis 8-37 part, Fructus Psoraleae 6-21 part, fresh pomegranate rind 8-44 part, Radix Glycyrrhizae 5-14 part.
In the scope of prescription medical material, preferred 3 prescription proportionings with better curative effect are out respectively (with parts by weight):
Proportioning 1: Fructus Evodiae 17 parts, the Radix Astragali 20 parts, Radix Codonopsis 24 parts, Flos Inulae 18 parts, Ramulus Cinnamomi 11 parts, Endothelium Corneum Gigeriae Galli 14 parts, Rhizoma Dioscoreae 15 parts, Herba Taraxaci 13 parts, Rhizoma Cimicifugae 12 parts, Fructus Aurantii 12 parts, 18 parts, Poria, Rhizoma Atractylodis 22 parts, Fructus Psoraleae 13 parts, fresh pomegranate rind 25 parts, 9 parts, Radix Glycyrrhizae.
Proportioning 2: Fructus Evodiae 19 parts, the Radix Astragali 22 parts, Radix Codonopsis 26 parts, Flos Inulae 16 parts, Ramulus Cinnamomi 13 parts, Endothelium Corneum Gigeriae Galli 14 parts, Rhizoma Dioscoreae 14 parts, Herba Taraxaci 14 parts, Rhizoma Cimicifugae 14 parts, Fructus Aurantii 13 parts, 19 parts, Poria, Rhizoma Atractylodis 24 parts, Fructus Psoraleae 12 parts, fresh pomegranate rind 27 parts, 10 parts, Radix Glycyrrhizae.
Proportioning 3: Fructus Evodiae 18 parts, the Radix Astragali 20 parts, Radix Codonopsis 25 parts, Flos Inulae 20 parts, Ramulus Cinnamomi 13 parts, Endothelium Corneum Gigeriae Galli 15 parts, Rhizoma Dioscoreae 15 parts, Herba Taraxaci 12 parts, Rhizoma Cimicifugae 13 parts, Fructus Aurantii 13 parts, 17 parts, Poria, Rhizoma Atractylodis 23 parts, Fructus Psoraleae 15 parts, fresh pomegranate rind 25 parts, 9 parts, Radix Glycyrrhizae.
The preparation method of Chinese medicine preparation of the present invention is following steps:
(1), in prescription ratio accurately take each taste Chinese crude drug, clean respectively, dry, pulverize, for subsequent use;
(2), get Endothelium Corneum Gigeriae Galli, Rhizoma Cimicifugae grinding, cross 80-120 mesh sieve, obtain fine powder a, for subsequent use;
(3), extracting liquorice and the Radix Astragali, parch respectively, grinding, crosses 80-120 mesh sieve, is mixed to get fine powder b, for subsequent use;
(4), get Fructus Evodiae, Radix Codonopsis, Flos Inulae, Ramulus Cinnamomi, Rhizoma Dioscoreae, Herba Taraxaci, Fructus Aurantii, Poria, Rhizoma Atractylodis, Fructus Psoraleae, fresh pomegranate rind, mixing, add 5-17 distilled water doubly, soak 4-24 hour, backflow decoction 3 times, each 1-6 hour, filter, mix 3 filtrates, when being evaporated to 60 DEG C, relative density of surveying is 1.32-1.35, then drying under reduced pressure obtains dry extract, dry extract is pulverized, grinding, cross 80-120 mesh sieve, obtain fine powder c, for subsequent use;
(5), by fine powder a, fine powder b and fine powder c mix homogeneously, add suitable adjuvant, modern general Chinese medicine preparation technology is utilized to make clinical required dosage form, the dosage forms such as such as tablet, capsule (containing soft capsule), powder, pill, granule, syrup, tincture.
The character Characteristic of the main raw material(s) of Chinese medicine preparation of the present invention:
Fructus Evodiae: this product is rutaceae Fructus Evodiae, stone tiger or the dry almost ripe fruit of thin hair Fructus Evodiae.Acrid in the mouth, hardship, hot in nature; Return liver, spleen, stomach, kidney channel; Dispersing cold for relieving pain, stopping nausea and vomiting by lowering the adverse flow of QI, supporing yang antidiarrheal.
The Radix Astragali: this product is the dry root of leguminous plant Radix Astagali or Radix Astragali.Sweet in the mouth, warm in nature; Return lung, spleen channel; Invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.
Radix Codonopsis: the dry root that this product is Campanulaceae Radix Codonopsis, element spends Radix Codonopsis (RADIX CODONOPSIS PILOSULAE from Northwest of China) or radix codonpsis tangshen.Sweet in the mouth, property is put down; Return spleen, lung meridian; Invigorating the spleen and replenishing QI, spleen invigorating lung benefiting.
Flos Inulae: be the head inflorescence of feverfew Flos Inulae, inula lineariifolia or inula Britannica etc.Salty in the mouth, warm in nature; Enter lung, liver, stomach warp; Expectorant, the therapeutic method to keep the adverse QI flowing downwards, softening the hard mass, row water.
Ramulus Cinnamomi: this product is the dry twig of canella Cortex Cinnamomi.Acrid in the mouth, sweet, warm in nature; GUIXIN, lung, urinary bladder channel; Diaphoresis expelling pathogenic factors from muscles, promoting the flow of QI-blood by warming the meridian, supporing yang activating QI, the flat gas that spins.
Endothelium Corneum Gigeriae Galli: this product is the dry inner wall of sandbag of Phasianidae animal man chicken.Sweet in the mouth, property is put down; Return spleen, stomach, small intestinal, urinary bladder channel; Invigorating the stomach and promoting digestion, arresting seminal emission.
Rhizoma Dioscoreae: this product is the dry rhizome of Dioscoreaceae plant Rhizoma Dioscoreae.Sweet in the mouth, property is put down; Return spleen, lung, kidney channel; Spleen reinforcing nourishing the stomach, promote the production of body fluid lung benefiting, the kidney invigorating arresting seminal emission.
Herba Taraxaci: this product is feverfew Herba Taraxaci, alkali ground Herba Taraxaci or belong to the dry herb of several plants together.Bitter in the mouth, sweet, cold in nature; Return liver, stomach warp; Heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, inducing diuresis for treating stranguria syndrome.
Rhizoma Cimicifugae: this product is the dry rhizome of ranunculaceae plant C.heracleifolia, Cimicifuga Dahurica or Rhizoma Cimicifugae.Acrid in the mouth, micro-sweet, cold nature; Return lung, spleen, stomach, large intestine channel; Deliver rash, heat-clearing and toxic substances removing, elevate a turnable ladder yang-energy.
Fructus Aurantii: this product is the dry immature fruit of rutaceae Citrus aurantium Linn. and variety thereof.Bitter in the mouth, pungent, sour, warm in nature; Return spleen, stomach warp.Regulating the flow of QI to ease the stomach, the stagnant relieving distension of row.
Poria: this product is the dry sclerotia of On Polyporaceae Poria.Sweet in the mouth, light, property is put down; GUIXIN, spleen, kidney channel; Eliminating dampness and diuresis, invigorating the spleen and regulating the stomach, mind tranquilizing and the heart calming.
Rhizoma Atractylodis: this product is the dry rhizome of feverfew Atractylodes lancea (Thunb.) DC. or Atractylis chinensis.Acrid in the mouth, hardship, warm in nature; Return spleen, stomach, Liver Channel; Drying damp and strengthening spleen, expelling wind and cold, improving eyesight.
Fructus Psoraleae: this product is the dry mature fruit of legumes psoraleae.Acrid in the mouth, hardship, warm in nature; Return kidney, spleen channel; Warming the kidney to activate YANG, improving inspiration by invigorating kidney-QI, antidiarrheal.
Pericarpium Granati: this product is the dry peel of Punicaceae plant Punica granatum L..Sour in the mouth, puckery, warm in nature; Return large intestine channel; Relieving diarrhea with astringents, hemostasis, anthelmintic.
Radix Glycyrrhizae: this product is the dry root of glycyrrhizic legume, Glycyrrhiza inflata Bat. or Glycyrrhiza glabra L..Sweet in the mouth, property is put down; GUIXIN, lung, spleen, stomach warp; Invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.
The side of Chinese medicine preparation of the present invention separates:
The Chinese prescription of this Chinese medicine preparation is with Radix Codonopsis, Rhizoma Atractylodis, the Radix Astragali, fresh pomegranate rind for monarch drug, invigorating the spleen and replenishing QI, drying damp and strengthening spleen, expelling wind and cold, invigorating QI to consolidate the body surface resistance, relieving diarrhea with astringents; With Flos Inulae, Fructus Evodiae, Poria, Endothelium Corneum Gigeriae Galli for ministerial drug, the expectorant therapeutic method to keep the adverse QI flowing downwards, supporing yang antidiarrheal, invigorating the spleen and regulating the stomach, invigorating the stomach and promoting digestion; With Fructus Psoraleae, Rhizoma Dioscoreae, Herba Taraxaci, Rhizoma Cimicifugae for adjuvant drug, warming the kidney to activate YANG, spleen reinforcing nourishing the stomach, dispersing swelling and dissipating binds, elevate a turnable ladder yang-energy; With Ramulus Cinnamomi, Fructus Aurantii for making medicine, promoting the flow of QI-blood by warming the meridian, supporing yang activating QI, regulating the flow of QI to ease the stomach, the stagnant relieving distension of row; With all property of medicine matter of Radix Glycyrrhizae mediation monarch, make all medicine synergism, negative and positive are taken mutually, mend and let out equilibrium, thus reach the therapeutic effect such as invigorating the spleen and replenishing QI, drying damp and strengthening spleen, expelling wind and cold, invigorating QI to consolidate the body surface resistance, supporing yang antidiarrheal, invigorating the spleen and regulating the stomach, warming the kidney to activate YANG, spleen reinforcing nourishing the stomach, dispersing swelling and dissipating binds, elevate a turnable ladder yang-energy, promoting the flow of QI-blood by warming the meridian, regulating the flow of QI to ease the stomach, very remarkable to the therapeutic effect of gastroptosis.
The present invention also discloses a kind of purposes of above-mentioned Chinese medicine preparation, i.e. the purposes of above-mentioned Chinese medicine preparation in preparation treatment gastroptosis medicine.The clinical trial display of Chinese medicine preparation of the present invention, the twice of the average cure rate of Chinese medicine preparation experimental group of the present invention to be 80.75% be matched group is many, average total effective rate is 95.8%, higher than matched group 17.9 percentage points, therapeutic effect is remarkable, and rapid-action, drug side effect is low, can be used as the drug use for the treatment of gastroptosis, clinical generalization value is high.
Compared with prior art, the technical advantage of Chinese medicine preparation of the present invention is, its instant effect, therapeutic effect be good, more after do not recur, have no side effect; And its preparation process is simple and easy to do, cost is low, preparation efficacy stability, universality are good, are applicable to suitability for industrialized production.
Detailed description of the invention
Embodiment 1
In order to verify the feasibility of Chinese prescription scope of the present invention and preparation method, and be follow-up test sampling, inventor have chosen representational prescription proportioning raw materials and has carried out the production of capsule, these prescription proportionings are respectively the boundary value of medical material scope, arbitrary value and 3 optimum ratios, be numbered A-F respectively, each proportioning raw materials is as shown in table 1:
Table 1 each proportioning raw materials table proportioning
(1), in ratio shown in table 1 accurately take each taste Chinese crude drug, clean respectively, dry, pulverize, for subsequent use;
(2), get Endothelium Corneum Gigeriae Galli, Rhizoma Cimicifugae grinding, cross 100 mesh sieves, obtain fine powder a, for subsequent use;
(3), extracting liquorice and the Radix Astragali, parch respectively, grinding, crosses 100 mesh sieves, is mixed to get fine powder b, for subsequent use;
(4), get Fructus Evodiae, Radix Codonopsis, Flos Inulae, Ramulus Cinnamomi, Rhizoma Dioscoreae, Herba Taraxaci, Fructus Aurantii, Poria, Rhizoma Atractylodis, Fructus Psoraleae, fresh pomegranate rind, mixing, adds the distilled water of 13 times, soak 18 hours, backflow decoction 3 times, each 3 hours, filter, mix 3 filtrates, when being evaporated to 60 DEG C, relative density of surveying is 1.32-1.35, then drying under reduced pressure obtains dry extract, dry extract is pulverized, grinding, cross 100 mesh sieves, obtain fine powder c, for subsequent use;
(5), by fine powder a, fine powder b and fine powder c mix homogeneously, add suitable adjuvant, utilize modern general Chinese medicine preparation technology to make capsule, specification is: 1.45g crude drug/capsules.
Embodiment 2
The toxicity test of Chinese medicine preparation of the present invention
(1) test material
1, test drug: obtained by the embodiment of the present invention 1, capsule is numbered A-F, specification is: 1.45g crude drug/capsules.Abolish capsule shells, add water and be modulated into the pastel of desired concn.
2, test animal used: regular grade NIH mice, body weight 23g ± 4g, male and female half and half, female mice is all without pregnant; SD rat, original body mass 228 ± 11g, male and female half and half, female rats is all without pregnant.Laboratory animal is bought from Miao Di bio tech ltd, Shanghai.
(2) acute toxicity test
Application mice carries out acute toxicity testing and shows: mouse stomach Chinese medicine capsules of the present invention, under 733.5g crude drug/kg dosage, after administration, mice occurs that light activity reduces, 1 hours recovers normal, Continuous Observation 7 days after administration, none dead mouse, and overall health of patients, diet, take the photograph water, urine and body weight increase all normal.Experimental result shows: the maximum dosage-feeding of mouse stomach Chinese medicine capsules of the present invention is 733.5g crude drug/kg/d(LD
50> 733.5g crude drug/kg).Chinese medicine preparation clinical application every day total amount of the present invention is 0.29g crude drug/kg/d; By weighing machine, the dosis tolerata of mouse stomach Chinese medicine preparation of the present invention is 2529.3 times of clinical patient.Point out this medicine acute toxicity extremely low, clinical drug safety.
(3), long term toxicity test
Select SD rat, give the Chinese medicine capsules of the present invention of Three doses: 52.2g crude drug/kg, 17.4g crude drug/kg, 5.8g crude drug/kg(per weight dosage is by 20 times of calculating of clinical application amount, and clinical application amount is according to Pharmacopoeia of the People's Republic of China version in 2010).Every day gavage once, continuous 90 days, after last administration 24 hours respectively group live and kill 1/2 animal (male and female half and half), all the other 1/2 animals continue that observations are alive after 2 weeks kills.Duration of test observes outward appearance, general behavior, food ration, the body weight change of animal; Within after administration 90 days, within 2 weeks, carry out the index checking such as hematology's (RBC, HB, reticulocyte, PLT, CT, WBC and classification) and blood biochemical (AST, ALT, ALP, Glu, BUN, Crea, TP, T.BIL, ALB, CHOL), urine biochemistry, organ coefficient, histopathology with drug withdrawal.
Result of the test shows: Chinese medicine preparation of the present invention is good at high, medium and low dosage treated animal general state, and outward appearance sign, behavioral activity, food-intake and body weight increase change all without exception; Three doses group and matched group hematological examination, blood biochemical analysis, urine biochemical analysis all in normal range, without significant difference between group; Each group of main organs histopathological examination shows no obvious abnormalities.These parameters drug withdrawal also had no change after 2 weeks.This test dosage is respectively 180,60,20 times of clinical medicine dose, according to result of the test: Chinese medicine preparation of the present invention has no significant effect rat in high, medium and low three dosage (52.2g crude drug/kg, 17.4g crude drug/kg, 5.8g crude drug/kg) administration in continuous 90 days, without clear and definite toxicity target organ and sensitive indicator, convalescent period observation also has no retardance toxic reaction, points out the dose safety of Chinese medicine preparation clinical practice of the present invention very high.
Embodiment 3
The clinical trial of Chinese medicine preparation of the present invention
1, physical data
The patient of this clinical trial is from certain First People's Hospital of city and certain institute of traditional Chinese medicine of city, from the Supreme People's Court and the Supreme People's Procuratorate from the patients with gastric disease of accepting for medical treatment year March in March, 2012 to 2015, select 330 examples altogether to make a definite diagnosis the patient suffering from gastroptosis and take part in clinical trial voluntarily, age 25-62 year, man 146 example, female 184 example, all patients are divided into three groups (matched group, test 1 group and test 2 groups), often organize 110 examples, and make these three groups in age, sex, the course of disease etc., have comparability on statistical significance.
2, trial drug
Contrast medicine: BUZHONG YIQI WAN, the accurate word Z11020244 of traditional Chinese medicines, Beijing Tongrentang Technology Development Co.ltd. Pharmaceutical Factory, specification: 6g/ bag.
Investigational agent: the capsule of what the embodiment of the present invention 1 was produced be numbered E and F, specification is: 1.45g crude drug/capsules.
3, test method
The oral contrast medicine of matched group, every day 3 times, each 6g, 4 hours, interval; Test 1 group of oral capsule being numbered E of patient, test 2 groups of oral capsules being numbered F of patient, every day 3 times, each 4,4 hours, interval; Within 3 weeks, be a course for the treatment of, treat 4 courses for the treatment of continuously, treatment terminates rear statistical analysis therapeutic outcome.
4, curative effect judgment criteria
Recovery from illness: through x-ray barivm meal fluoroscopy (screem) gastric angle more than two interiliac lines, clinical symptoms disappears completely.
Effective: x-ray barivm meal fluoroscopy (screem) body of stomach to move to former sagging more than 1/2, clinical symptoms work improves.
Take a turn for the better: x-ray barivm meal fluoroscopy (screem) body of stomach to move but not enough former sagging 1/2, partial symptoms is improved.
Invalid: x-ray barivm meal fluoroscopy (screem) and symptom are all without change, even more serious.
5, result of the test
After test all terminates, by as shown in table 2 for result of the test statistical analysis, contrasting 1 group has 6 examples to come off, and the case load completing test is 104; Testing 1 group has 4 examples to come off, and the case load completing test is 106; Testing 2 groups has 3 examples to come off, and the case load completing test is 107.
Table 2 result of the test statistical analysis table
6, conclusion
The result of the test display of table 2, the twice of the average cure rate of Chinese medicine preparation experimental group of the present invention to be 80.75% be matched group is many, average total effective rate is 95.8%, higher than matched group 17.9 percentage points, absolutely prove, relative to prior art, the present invention has very significant technical advantage, achieve breakthrough technological progress in this technical field, obtain beyond thought scientific achievement.
Claims (5)
1. treat the Chinese medicine preparation of gastroptosis for one kind, it is characterized in that, described Chinese medicine preparation is prepared from by the Chinese crude drug of following weight portion: Fructus Evodiae 7-28 part, Radix Astragali 7-34 part, Radix Codonopsis 8-40 part, Flos Inulae 7-29 part, Ramulus Cinnamomi 6-16 part, Endothelium Corneum Gigeriae Galli 6-22 part, Rhizoma Dioscoreae 6-26 part, Herba Taraxaci 6-20 part, Rhizoma Cimicifugae 6-19 part, Fructus Aurantii 6-18 part, Poria 7-30 part, Rhizoma Atractylodis 8-37 part, Fructus Psoraleae 6-21 part, fresh pomegranate rind 8-44 part, Radix Glycyrrhizae 5-14 part.
2. the Chinese medicine preparation for the treatment of gastroptosis as claimed in claim 1, it is characterized in that, described Chinese medicine preparation is prepared from by the Chinese crude drug of following weight portion: Fructus Evodiae 17 parts, the Radix Astragali 20 parts, Radix Codonopsis 24 parts, Flos Inulae 18 parts, Ramulus Cinnamomi 11 parts, Endothelium Corneum Gigeriae Galli 14 parts, Rhizoma Dioscoreae 15 parts, Herba Taraxaci 13 parts, Rhizoma Cimicifugae 12 parts, Fructus Aurantii 12 parts, 18 parts, Poria, Rhizoma Atractylodis 22 parts, Fructus Psoraleae 13 parts, fresh pomegranate rind 25 parts, 9 parts, Radix Glycyrrhizae.
3. the Chinese medicine preparation for the treatment of gastroptosis as claimed in claim 1, it is characterized in that, described Chinese medicine preparation is prepared from by the Chinese crude drug of following weight portion: Fructus Evodiae 19 parts, the Radix Astragali 22 parts, Radix Codonopsis 26 parts, Flos Inulae 16 parts, Ramulus Cinnamomi 13 parts, Endothelium Corneum Gigeriae Galli 14 parts, Rhizoma Dioscoreae 14 parts, Herba Taraxaci 14 parts, Rhizoma Cimicifugae 14 parts, Fructus Aurantii 13 parts, 19 parts, Poria, Rhizoma Atractylodis 24 parts, Fructus Psoraleae 12 parts, fresh pomegranate rind 27 parts, 10 parts, Radix Glycyrrhizae.
4. the Chinese medicine preparation for the treatment of gastroptosis as claimed in claim 1, it is characterized in that, described Chinese medicine preparation is prepared from by the Chinese crude drug of following weight portion: Fructus Evodiae 18 parts, the Radix Astragali 20 parts, Radix Codonopsis 25 parts, Flos Inulae 20 parts, Ramulus Cinnamomi 13 parts, Endothelium Corneum Gigeriae Galli 15 parts, Rhizoma Dioscoreae 15 parts, Herba Taraxaci 12 parts, Rhizoma Cimicifugae 13 parts, Fructus Aurantii 13 parts, 17 parts, Poria, Rhizoma Atractylodis 23 parts, Fructus Psoraleae 15 parts, fresh pomegranate rind 25 parts, 9 parts, Radix Glycyrrhizae.
5. the Chinese medicine preparation of the treatment gastroptosis as described in any one of claim 1-4, is characterized in that: the dosage form of described Chinese medicine preparation is tablet, capsule, powder, pill, granule, syrup or tincture.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN106822741A (en) * | 2017-01-23 | 2017-06-13 | 郑州景鸿畜牧科技有限公司 | Treat the Chinese medicine preparation and preparation method of gastroptosis |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103083586A (en) * | 2012-12-11 | 2013-05-08 | 宋协勘 | Traditional Chinese medicine for treating gastroptosis |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103083586A (en) * | 2012-12-11 | 2013-05-08 | 宋协勘 | Traditional Chinese medicine for treating gastroptosis |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106822741A (en) * | 2017-01-23 | 2017-06-13 | 郑州景鸿畜牧科技有限公司 | Treat the Chinese medicine preparation and preparation method of gastroptosis |
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Application publication date: 20160106 |