CN104644911A - Compound traditional Chinese medicinal preparation for treating gout - Google Patents
Compound traditional Chinese medicinal preparation for treating gout Download PDFInfo
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- CN104644911A CN104644911A CN201310576114.6A CN201310576114A CN104644911A CN 104644911 A CN104644911 A CN 104644911A CN 201310576114 A CN201310576114 A CN 201310576114A CN 104644911 A CN104644911 A CN 104644911A
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Abstract
The invention discloses a compound traditional Chinese medicinal preparation, especially a compound traditional Chinese medicinal preparation for treating gout. The compound traditional Chinese medicine preparation for treating gout is prepared by the following raw bulk drugs by weight: 260-340 parts of rheum officinale, 160-240 parts of Plantain seed, 160-240 parts of Rhizoma alismatis, 160-240 parts of Cyathnla capitata Moq., 60-140 parts of radix stephaniae tetrandrae, 0.02-0.2 part of microcrystalline cellulose and 0.05-0.3 part of starch. The medicine has the advantages of good treatment effect, short treatment course, low cost, high cure rate, low recurrence rate, convenience for usage, no side or toxic effect and good stability.
Description
Technical field
The present invention relates to a kind of compound Chinese medicinal preparation, particularly a kind of compound Chinese medicinal preparation for the treatment of gout.
Background technology
Gout is a class disease of the chronic metabolic derangements caused by purine metabolic disturbance, due to the disorder of purine metabolism, causes uric acid in blood excessive concentration, finally forms crystalline solid, lodge in soft tissue and produce inflammation, diseases induced.Mainly be formed as main clinical characteristics with hyperuricemia, acute gouty arthritis recurrent exerbation, tophaceous deposition, gouty arthritis,chronic and joint deformity, parenchymal lesion of the kidney and uric-acid calculus.Often involving kidney causes chronic interstitial nephritis and uric acid kidney stones to be formed, and occurs together mutually as diseases such as hypertension, coronary heart disease, diabetes with other metabolic diseases, brings serious harm to human health.
According to Historical Data Data About, in western history, many famous emperors and ministers all suffer from gout, such as Julius Caesar, Louis seven generation etc., and first generation ancestral Kublai Khan just endures the hardship of gout old age to the fullest extent because of insobriety, and his a military officer that cannot normally walk and ride is gone into battle.Therefore gout is also known as " disease of king ", " emperor is sick ", " affluenza "." gout " one word appear in the medical science ancient books and records in Northern and Southern Dynasties' period the earliest, because its pain is come soon as a gust of wind, therefore therefore name.Ancient times are also known as " arthralgia aggravated by cold ".Ancient Greek's well-known doctor's Hippcrates claims gout to be " not walking disease ", and gout belongs to Chinese medicine " arthromyodynia " category." gout is namely interior through arthralgia aggravated by cold " " treatise on blood trouble ": " gout, general numbness and hypoesthesia, limbs pain, modern name gout, Gu say arthromyodynia ".
Along with the change of people life style and dietary structure, the prevalence of gout in ascendant trend gradually, and presents the trend of rejuvenation, has become a kind of commonly encountered diseases, frequently-occurring disease.According to epidemiology statistics, in different regions, the world, the prevalence of gout is not from 1% ~ 15.3% etc.Be apt to occur in male and menopausal woman, male is more than women, and M-F is 20 to 1, and brain worker is higher than physical labourer, and coastal area is higher than the ill feature of hinterland.In China, Patients with Hyperuricemia number reaches 1,200,000,000, and increases sharply with higher annual rate of growth every year.Gout has become the second largest metabolism class disease that China is only second to diabetes.
Goat except severe joint pain can be caused, deformity, outside dysfunction and renal damage, also frequent with or the illness such as complicated with diabetes, coronary heart disease, hypertension, obesity, blood fat disorder, can cause higher lethal disability rate, it is very urgent to prevent and treat gout.
But for this disease, there is no special targeted drug clinically, base therapy target is clinically: relief of symptoms, prevention of recurrence and complication.The antacid medicine that many employings are single or antisecretory carry out relief of symptoms, and these medicine multiactions are in gastric, do not play real therapeutical effect to lesions position, and most severe patient needs to carry out operative treatment.Drug main used based on colchicine, nonsteroidal antiinflammatory drug, hormone, promotion urate excretion medicine (as probenecid, sulfinpyrazone and benzbromarone) and will suppress uric acid synthetic drug (allopurinol) clinically.Acute period of disease mainly applies colchicine, nonsteroidal antiinflammatory drug, hormone, catabasis is mainly applied and promotes urate excretion medicine, suppression uric acid synthetic drug, but such medicine long-term taking, damage is in various degree had with stomach, severe patient can cause the exception of liver, kidney, even can also cause the diseases such as bone marrow depression, oligospermia, hepatic necrosis, neurotoxicity, therefore such poisonous side effect of medicine is comparatively large, unsuitable long-term taking.
Summary of the invention
The technical problem of solution required for the present invention is to provide a kind of compound Chinese medicinal preparation for the treatment of gout, and it is pure Chinese medicinal preparation, and Clinical practice is effective, short treating period, and cost is low, and cure rate is high, and relapse rate is low, and taking convenience has no side effect, good stability.
The weight ratio scope of each raw material of the present invention is through inventor and carries out a large amount of groping to draw with Test Summary, and the weight ratio of each raw material all has good curative effect at described weight range.The present invention adopts described prescription to combine, and is made by these drug regimens each efficacy of drugs produce synergism, thus effectively can treat pain wind action.
For solving the problem, the present invention is achieved in that
The compound Chinese medicinal preparation for the treatment of gout, it is prepared from by following portions by weight by following raw material: Radix Et Rhizoma Rhei 260-340 part, Semen Plantaginis 160-240 part, Rhizoma Alismatis 160-240 part, Radix Cyathulae 160-240 part, Radix Stephaniae Tetrandrae 60-140 part, microcrystalline Cellulose 0.02-0.2 part, starch 0.05-0.3 part.
The compound Chinese medicinal preparation of above-mentioned treatment gout, it is prepared from by following portions by weight by following raw material: Radix Et Rhizoma Rhei 280-320 part, Semen Plantaginis 180-220 part, Rhizoma Alismatis 180-220 part, Radix Cyathulae 180-220 part, Radix Stephaniae Tetrandrae 80-120 part, microcrystalline Cellulose 0.05-0.1 part, starch 0.07-0.2 part.
The compound Chinese medicinal preparation of above-mentioned treatment gout, it is prepared from by following portions by weight by following raw material: Radix Et Rhizoma Rhei 300 parts, Semen Plantaginis 200 parts, Rhizoma Alismatis 200 parts, Radix Cyathulae 200 parts, Radix Stephaniae Tetrandrae 100 parts, microcrystalline Cellulose 0.07 part, starch 0.1 part.
Above-mentioned Semen Plantaginis is wine Semen Plantaginis, Rhizoma Alismatis is Rhizoma Alismatis (processeded with salt), Radix Cyathulae is wine Radix Cyathulae.
The compound Chinese medicinal preparation of above-mentioned treatment gout can be tablet, capsule.
The preparation method of the compound Chinese medicinal preparation tablet of above-mentioned treatment gout gets the Radix Et Rhizoma Rhei of described parts by weight, Semen Plantaginis, Rhizoma Alismatis, Radix Cyathulae, Radix Stephaniae Tetrandrae, is crushed to 1000 orders, adds microcrystalline Cellulose, starch, mixing granulation, dry, tabletting and get final product.
The preparation method of the compound Chinese medicinal preparation capsule of above-mentioned treatment gout gets the Radix Et Rhizoma Rhei of described weight portion, Semen Plantaginis, Rhizoma Alismatis, Radix Cyathulae, Radix Stephaniae Tetrandrae, is crushed to 1000 orders, adds microcrystalline Cellulose, starch, mixing granulation, dry, incapsulates and get final product.
Advantage of the present invention and beneficial outcomes as follows:
The medicine group that the present invention treats the compound Chinese medicinal preparation of gout is Radix Et Rhizoma Rhei, Semen Plantaginis, Rhizoma Alismatis, Radix Cyathulae, Radix Stephaniae Tetrandrae, microcrystalline Cellulose, starch.Wherein Radix Et Rhizoma Rhei, Semen Plantaginis, Rhizoma Alismatis, Radix Cyathulae, Radix Stephaniae Tetrandrae are the entity composition of medicine, and decide drug main and want aspect, microcrystalline Cellulose, starch contribute to the molding of medicine and improves rate of release and the stability of medicine.
Product of the present invention presses monarch formulation principle, and its monarch drug Radix Et Rhizoma Rhei attacks intestinal stasis relieving, purging fire and cooling blood, blood circulation promoting and blood stasis dispelling; Ministerial drug Semen Plantaginis, Rhizoma Alismatis adopt wine Semen Plantaginis, Rhizoma Alismatis (processeded with salt) respectively, diuretic, eliminating dampness by diuresis, treating strangurialy expel the heat-evil, the object of wine Semen Plantaginis is used to be change that it is cold, a surname's row medicine gesture, current meridian qi and blood, eliminating evilly to go out, use the more non-impairment of YIN in diuretic of Rhizoma Alismatis (processeded with salt), the fire mutually of rash action can be conquered; Expelling wind and removing dampness, the pain relieving diuretic such as adjuvant drug Radix Stephaniae Tetrandrae; Medicine Radix Cyathulae is made then to adopt wine Radix Cyathulae, can not only blood circulation promoting and blood stasis dispelling, priming is descending, invigorating the liver and kidney, treating stranguria puckery, and more sharp thing promoting blood circulation to restore menstrual flow after Radix Cyathulae processed with wine, easing joint movement.All medicines share, thus reach the effect for the treatment of both the principal and secondary aspects of a disease.
Detailed description of the invention
Description below by way of detailed description of the invention is described in further detail the present invention, but this is not limitation of the present invention, those skilled in the art are according to basic thought of the present invention, various amendment or improvement can be made, but only otherwise depart from basic thought of the present invention, all within the scope of the present invention.
embodiment 1
Medicine of the present invention is by following important part preparation by following raw material medicaments.
Radix Et Rhizoma Rhei 260 parts, Semen Plantaginis 180 parts, Rhizoma Alismatis 200 parts, Radix Cyathulae 220 parts, Radix Stephaniae Tetrandrae 140 parts, microcrystalline Cellulose 0.02 part, starch 0.3 part.
Method said medicine being made tablet is: get the Radix Et Rhizoma Rhei of described important part, Semen Plantaginis, Rhizoma Alismatis, Radix Cyathulae, Radix Stephaniae Tetrandrae, be crushed to 1000 orders, add microcrystalline Cellulose, starch, mixing granulation, dry, tabletting and get final product.
embodiment 2
Medicine of the present invention is by following important part preparation by following raw material medicaments.
Radix Et Rhizoma Rhei 280 parts, Semen Plantaginis 200 parts, Rhizoma Alismatis 220 parts, Radix Cyathulae 240 parts, Radix Stephaniae Tetrandrae 60 parts, microcrystalline Cellulose 0.05 part, starch 0.05 part.
Method said medicine being made tablet is: get the Radix Et Rhizoma Rhei of described important part, Semen Plantaginis, Rhizoma Alismatis, Radix Cyathulae, Radix Stephaniae Tetrandrae, be crushed to 1000 orders, add microcrystalline Cellulose, starch, mixing granulation, dry, tabletting and get final product.
embodiment 3
Medicine of the present invention is by following important part preparation by following raw material medicaments.
Radix Et Rhizoma Rhei 300 parts, Semen Plantaginis 220 parts, Rhizoma Alismatis 240 parts, Radix Cyathulae 160 parts, Radix Stephaniae Tetrandrae 80 parts, microcrystalline Cellulose 0.07 part, starch 0.07 part.
Method said medicine being made capsule is: get the Radix Et Rhizoma Rhei of described important part, Semen Plantaginis, Rhizoma Alismatis, Radix Cyathulae, Radix Stephaniae Tetrandrae, be crushed to 1000 orders, add microcrystalline Cellulose, starch, mixing granulation, dry, incapsulates and get final product.
embodiment 4
Medicine of the present invention is by following important part preparation by following raw material medicaments.
Radix Et Rhizoma Rhei 320 parts, Semen Plantaginis 240 parts, Rhizoma Alismatis 160 parts, Radix Cyathulae 180 parts, Radix Stephaniae Tetrandrae 100 parts, microcrystalline Cellulose 0.1 part, starch 0.1 part.
Method said medicine being made capsule is: get the Radix Et Rhizoma Rhei of described important part, Semen Plantaginis, Rhizoma Alismatis, Radix Cyathulae, Radix Stephaniae Tetrandrae, be crushed to 1000 orders, add microcrystalline Cellulose, starch, mixing granulation, dry, incapsulates and get final product.
embodiment 5
Medicine of the present invention is by following important part preparation by following raw material medicaments.
Radix Et Rhizoma Rhei 340 parts, Semen Plantaginis 160 parts, Rhizoma Alismatis 180 parts, Radix Cyathulae 200 parts, Radix Stephaniae Tetrandrae 120 parts, microcrystalline Cellulose 0.2 part, starch 0.2 part.
Method said medicine being made capsule is: get the Radix Et Rhizoma Rhei of described important part, Semen Plantaginis, Rhizoma Alismatis, Radix Cyathulae, Radix Stephaniae Tetrandrae, be crushed to 1000 orders, add microcrystalline Cellulose, starch, mixing granulation, dry, tabletting and get final product.
embodiment 6
Medicine of the present invention is by following important part preparation by following raw material medicaments.
Radix Et Rhizoma Rhei 340 parts, Semen Plantaginis 160 parts, Rhizoma Alismatis 160 parts, Radix Cyathulae 160 parts, Radix Stephaniae Tetrandrae 60 parts, microcrystalline Cellulose 0.02 part, starch 0.3 part.
Method said medicine being made capsule is: get the Radix Et Rhizoma Rhei of described important part, Semen Plantaginis, Rhizoma Alismatis, Radix Cyathulae, Radix Stephaniae Tetrandrae, be crushed to 1000 orders, add microcrystalline Cellulose, starch, mixing granulation, dry, tabletting and get final product.
embodiment 7
Medicine of the present invention is by following important part preparation by following raw material medicaments.
Radix Et Rhizoma Rhei 260 parts, Semen Plantaginis 240 parts, Rhizoma Alismatis 240 parts, Radix Cyathulae 240 parts, Radix Stephaniae Tetrandrae 140 parts, microcrystalline Cellulose 002 part, starch 0.05 part.
Method said medicine being made capsule is: get the Radix Et Rhizoma Rhei of described important part, Semen Plantaginis, Rhizoma Alismatis, Radix Cyathulae, Radix Stephaniae Tetrandrae, be crushed to 1000 orders, add microcrystalline Cellulose, starch, mixing granulation, dry, tabletting and get final product.
Claims (7)
1. treat the compound Chinese medicinal preparation of gout, it is characterized in that it is prepared from by following portions by weight by following raw material: Radix Et Rhizoma Rhei 260-340 part, Semen Plantaginis 160-240 part, Rhizoma Alismatis 160-240 part, Radix Cyathulae 160-240 part, Radix Stephaniae Tetrandrae 60-140 part, microcrystalline Cellulose 0.02-0.2 part, starch 0.05-0.3 part.
2. the compound Chinese medicinal preparation for the treatment of gout according to claim 1, it is characterized in that it is prepared from by following portions by weight by following raw material: Radix Et Rhizoma Rhei 280-320 part, Semen Plantaginis 180-220 part, Rhizoma Alismatis 180-220 part, Radix Cyathulae 180-220 part, Radix Stephaniae Tetrandrae 80-120 part, microcrystalline Cellulose 0.05-0.1 part, starch 0.07-0.2 part.
3. the compound Chinese medicinal preparation for the treatment of gout according to claim 1, is characterized in that it is prepared from by following portions by weight by following raw material: Radix Et Rhizoma Rhei 300 parts, Semen Plantaginis 200 parts, Rhizoma Alismatis 200 parts, Radix Cyathulae 200 parts, Radix Stephaniae Tetrandrae 100 parts, microcrystalline Cellulose 0.07 part, starch 0.1 part.
4., according to claim 1,2,3, it is characterized in that described Semen Plantaginis is wine Semen Plantaginis, Rhizoma Alismatis is Rhizoma Alismatis (processeded with salt), Radix Cyathulae is wine Radix Cyathulae.
5. the compound Chinese medicinal preparation of the treatment gout according to claim 1,2,3 can be tablet, capsule.
6. treat the preparation method of the compound Chinese medicinal preparation of gout according to claim 1, it is characterized in that the compound Chinese medicinal preparation method for preparing tablet thereof of described treatment gout is, get the Radix Et Rhizoma Rhei of described parts by weight, Semen Plantaginis, Rhizoma Alismatis, Radix Cyathulae, Radix Stephaniae Tetrandrae, be crushed to 1000 orders, add microcrystalline Cellulose, starch, mixing granulation, drying, tabletting and get final product.
7. treat the preparation method of the compound Chinese medicinal preparation of gout according to claim 1, it is characterized in that the Herbal compound capsule agent preparation method of described treatment gout is, get the Radix Et Rhizoma Rhei of described weight portion, Semen Plantaginis, Rhizoma Alismatis, Radix Cyathulae, Radix Stephaniae Tetrandrae, be crushed to 1000 orders, add microcrystalline Cellulose, starch, mixing granulation, drying, incapsulates and get final product.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201310576114.6A CN104644911A (en) | 2013-11-18 | 2013-11-18 | Compound traditional Chinese medicinal preparation for treating gout |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201310576114.6A CN104644911A (en) | 2013-11-18 | 2013-11-18 | Compound traditional Chinese medicinal preparation for treating gout |
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1698701A (en) * | 2005-05-13 | 2005-11-23 | 一笑堂（湖南）制药有限公司 | Gout relaxing tablet and preparation method thereof |
| CN1706453A (en) * | 2005-05-16 | 2005-12-14 | 广州固志医药科技开发有限公司 | Gout resisting Chinese medicine composition and its prepn process |
| CN1709454A (en) * | 2005-07-04 | 2005-12-21 | 北京润德康医药科技有限公司 | Chinese medicine formulation for treating arthrolithiasis, and its preparing method |
| CN101167902A (en) * | 2007-11-12 | 2008-04-30 | 修正药业集团股份有限公司 | Method for preparing traditional Chinese medicine preparation for treating gout |
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2013
- 2013-11-18 CN CN201310576114.6A patent/CN104644911A/en not_active Withdrawn
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1698701A (en) * | 2005-05-13 | 2005-11-23 | 一笑堂（湖南）制药有限公司 | Gout relaxing tablet and preparation method thereof |
| CN1706453A (en) * | 2005-05-16 | 2005-12-14 | 广州固志医药科技开发有限公司 | Gout resisting Chinese medicine composition and its prepn process |
| CN1709454A (en) * | 2005-07-04 | 2005-12-21 | 北京润德康医药科技有限公司 | Chinese medicine formulation for treating arthrolithiasis, and its preparing method |
| CN101167902A (en) * | 2007-11-12 | 2008-04-30 | 修正药业集团股份有限公司 | Method for preparing traditional Chinese medicine preparation for treating gout |
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Application publication date: 20150527 |