CN104623453A - Medicinal preparation for treating mammary sclerosis of women and preparation method thereof - Google Patents

Medicinal preparation for treating mammary sclerosis of women and preparation method thereof Download PDF

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CN104623453A
CN104623453A CN201510027221.2A CN201510027221A CN104623453A CN 104623453 A CN104623453 A CN 104623453A CN 201510027221 A CN201510027221 A CN 201510027221A CN 104623453 A CN104623453 A CN 104623453A
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rhizoma
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herba
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刘保和
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Abstract

The invention discloses a medicinal preparation for treating mammary sclerosis of women. The medicinal preparation is mainly prepared from the following medicinal raw materials in parts by weight: 10-15 parts of dried tangerine peels, 3-6 parts of common nipplewort herb, 9-15 parts of nutgrass galingale rhizomes, 6-9 parts of herba hyperici elodeoidis, 10-16 parts of unibract fritillary bulbs, 8-15 parts of liquorice roots, 9-12 parts of safflowers, 10-20 parts of mongolian dandelion herb, 10-20 parts of honeycombs, 10-20 parts of towel gourd vegetable sponges, 9-15 parts of common burreed rhizomes, 4-9 parts of Chinese brake herb, 8-16 parts of common anemarrhena rhizomes, 9-14 parts of pepperweed seeds and 5-10 parts of rhizoma corydalis. The components of the medicinal preparation are combined scientifically and take effect synergistically, and the obtained medicinal preparation is convenient to take and has a significant effect.

Description

The pharmaceutical preparation for the treatment of women breast expectorant and preparation
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to pharmaceutical preparation and the preparation for the treatment of women " newborn expectorant ".
Background technology
Breast expectorant, name of disease.Knot lump diabrosis person in breast.See in " Yangke Xinde Ji, Experience Gained in Treating External Diseases " volume.How because the Liver Channel stagnation of QI forms, or hot and suffocating through mental disorder by stomach caused by.This book is pointed out: " have nodule in the breast, begin not have a pain, continue indistinct pain then, or body is had a fever, and gradually becomes pus, diabrosis person, this newborn expectorant." doctor trained in Western medicine is interpreted as, and is mostly the result that the haematogenous being secondary to lung or tuberculosis of mesentric lymph nodes is sent out, or send out or direct extension and the disease that causes because contiguous tuberculose focus (rib, breastbone, pleura or axillary lymph nodes etc.) is driven in the wrong direction through lymphatic vessel.Clinical manifestation is without heating.Form cold pus infections after lump is softening, can pass to skin and form fistula or sinus tract, discharge the thin pus having cheesy chip; The lump of a few patients becomes lump through fibrosis, mammary contour is changed and retracted nipple, not easily differentiates with breast carcinoma.For the Therapeutic Method of this disease, be first antituberculosis therapy, common drug has isoniazid tablets, rifampicin tablets, streptomycin etc.Operative treatment, Chinese medical and herbal therapy and nutrition of whole body supporting treatment etc. can be coordinated as required simultaneously.
Publication No. CN 104127793 A(application number 201410366469.7) Chinese patent literature disclose a kind of Chinese medicine composition for the treatment of tuberculosis of breast, select to have depressed liver-energy dispersing and QI regulating, nourishing YIN to lower pathogenic fire, dissipating phlegm and resolving masses, promoting flow of QI and blood, the Chinese medicine Radix Kadsurae Coccineae of dispersing swelling and dissipating binds, Lignum seu Radix Acronychiae, Flos Amomi villosi, Herba Dendrobii, Radix Antiotrematis dunniani, Radix Embeliae blinii, Radix Hydrangeae Strigosae, Radix Chimonanthi praecocis, Folium Caesalpiniae Cristae make Orally-administered decoction, Herba mazi japonici, Herba Begoniae Cathyanae, Bulbus scillae scilloidis, Herba Lysimachiae Circaeoidis, Cortex Phyllanthi, Folium spiraeae japonicae make externally-applied ointment.Publication No. CN 103007187 A(application number 201210455715.7) Chinese patent literature disclose a kind of breast health-care patch and method for making thereof, by different modes extract component by Chinese medicine medicines such as Rhizoma Curcumae, Myrrha, Olibanum, Flos Lonicerae, Rhizoma Chuanxiong, Herba Portulacaes, add a certain proportion of Mel, vinegar, distilled water and glycerol and be mixed into paste, spread out into Chinese medicinal ingredients layer under room temperature, with spun laced fabric and release paper press mold, be carved into the shape being beneficial to stickup again.Publication number CN 101342288 A(application number 200810146536.9) Chinese patent literature disclose one and treat lymph, tuberculosis of breast and psoriasic traditional Chinese medical science plaster, the present invention's medical material used is made up of Radix Notoginseng, Agkistrodon, Sanguis Draxonis, Semen Strychni, Jiang Zi, Herba speranskiae tuberculatae, Radix Saposhnikoviae, Flos Carthami, Olibanum, pollen, Radix Et Rhizoma Rhei, Rhizoma Coptidis, Cortex Phellodendri, Radix Angelicae Pubescentis, Semen Armeniacae Amarum, Fructus Schisandrae Chinensis, Plumbum preparatium.
In modern medicine, the antituberculotics that western medical treatment uses mostly can only mitigate the disease, dependency and side effect larger, comparatively speaking, Chinese traditional treatment is more safe and effective, and current traditional Chinese medical science formula is less, therefore the research of necessary reinforcement contrast aspect pharmaceutical formulation.
Summary of the invention
For the problem of prior art, the object of this invention is to provide a kind of Be very effective, take the pharmaceutical preparation of the wide treatment women of safe and applicable " newborn expectorant ".
Technical scheme of the present invention is:
The pharmaceutical preparation for the treatment of women " newborn expectorant ", is prepared from primarily of following bulk drugs, is weight portion: Pericarpium Citri Reticulatae 10-15; Hera lapsanae apogonoidis 3-6; Rhizoma Cyperi 9-15; Herba hyperici elodeoidis 6-9; Bulbus Fritillariae Cirrhosae 10-16; Radix Glycyrrhizae 8-15; Flos Carthami 9-12; Herba Taraxaci 10-20; Nidus Vespae 10-20; Retinervus Luffae Fructus 10-20; Rhizoma scirpi 9-15; Herba pteridis vittatae 4-9; Rhizoma Anemarrhenae 8-16; Semen Lepidii (Semen Descurainiae) 9-14; Rhizoma Corydalis 5-10.
Preferably, Pericarpium Citri Reticulatae 11-14; Hera lapsanae apogonoidis 4-5; Rhizoma Cyperi 11-13; Herba hyperici elodeoidis 7-8; Bulbus Fritillariae Cirrhosae 12-14; Radix Glycyrrhizae 10-13; Flos Carthami 10-11; Herba Taraxaci 12-18; Nidus Vespae 12-18; Retinervus Luffae Fructus 13-17; Rhizoma scirpi 11-13; Herba pteridis vittatae 5-8; Rhizoma Anemarrhenae 10-14; Semen Lepidii (Semen Descurainiae) 10-13; Rhizoma Corydalis 6-9.
More preferably: Pericarpium Citri Reticulatae 12.5; Hera lapsanae apogonoidis 4.5; Rhizoma Cyperi 12; Herba hyperici elodeoidis 7.5; Bulbus Fritillariae Cirrhosae 13; Radix Glycyrrhizae 11.5; Flos Carthami 10.5; Herba Taraxaci 15; Nidus Vespae 15; Retinervus Luffae Fructus 15; Rhizoma scirpi 12; Herba pteridis vittatae 6.5; The Rhizoma Anemarrhenae 12; Semen Lepidii (Semen Descurainiae) 11.5; Rhizoma Corydalis 7.5.
The pharmaceutical preparation of described treatment women " newborn expectorant ", be made into pharmaceutically acceptable decoction, its preparation method is:
(1) get Nidus Vespae and clean removing impurity, toast under being placed in 180 DEG C of environment 8-16 minute (preferred, toast 12 minutes), be placed on immediately in vinegar liquid after taking-up and soak, pull out, drying, to pulverize;
(2) get after Flos Carthami cleans, add Chinese liquor, soaks 10-20 minute (preferred: immersion 12-18 minute; Be more preferably: soak 15 minutes), the steaming and decocting of sealing slow fire is to dry, and taking-up is dried;
(3) by Pericarpium Citri Reticulatae, Rhizoma Cyperi, Bulbus Fritillariae Cirrhosae, Radix Glycyrrhizae, Retinervus Luffae Fructus, rhizoma scirpi, the Rhizoma Anemarrhenae, Semen Lepidii (Semen Descurainiae) and Rhizoma Corydalis clear water drip washing moistening, be placed in marmite, add water and do not have medical material 5cm, big fire is heated to boiling, turns little fire and decocts 30-50 minute (preferably: little fire decocts 35-45 minute; Be more preferably: little fire decocts 40 minutes), filter after closing fire, collect filtrate;
(4) Hera lapsanae apogonoidis, Herba hyperici elodeoidis, Herba Taraxaci and Herba pteridis vittatae is clean, cutting, is placed in parch container, the micro-stir-fry of little fire 5 minutes, pulverizes 180-220 mesh sieve (preferred: to pulverize 190-210 mesh sieve after taking out together with step (1) (2) made crude drug; Be more preferably: pulverized 200 mesh sieves), obtain medicated powder;
(5) by step (3) and (4) gained filtrate and medicated powder mix homogeneously, sterilizing encapsulates to obtain decoction.
The preparation method of the pharmaceutical preparation decoction of described treatment women " newborn expectorant ", the amount adding Chinese liquor in step (2) is the 4-6 of crude drug weight doubly (preferred: the amount adding Chinese liquor is 5 times of crude drug weight).
The pharmaceutical preparation of described treatment women " newborn expectorant ", be made into pharmaceutically acceptable powder, its preparation method is:
(1) get Nidus Vespae and clean removing impurity, toast under being placed in 180 DEG C of environment 8-16 minute (preferred, toast 12 minutes), be placed on immediately in vinegar liquid after taking-up and soak, pull out, drying, to pulverize;
(2) get after Flos Carthami cleans, add Chinese liquor, soaks 10-20 minute (preferred: immersion 12-18 minute; Be more preferably: soak 15 minutes), the steaming and decocting of sealing slow fire is to dry, and taking-up is dried;
(3) by Pericarpium Citri Reticulatae, Rhizoma Cyperi, Bulbus Fritillariae Cirrhosae, Radix Glycyrrhizae, Retinervus Luffae Fructus, rhizoma scirpi, the Rhizoma Anemarrhenae, Semen Lepidii (Semen Descurainiae) and Rhizoma Corydalis clear water drip washing moistening, be placed in marmite, add water and do not have medical material 5cm, big fire is heated to boiling, turns little fire and decocts 30-50 minute (preferably: little fire decocts 35-45 minute; Be more preferably: little fire decocts 40 minutes), close fire first 15 minutes, then add clean Hera lapsanae apogonoidis, Herba hyperici elodeoidis, Herba Taraxaci and Herba pteridis vittatae, filtered while hot, collect filtrate;
(4) by step (3) gained filtrate spraying dry, pulverize together with step (1) (2) gained crude drug, encapsulate to obtain powder.
The preparation method of the pharmaceutical preparation powder of described treatment women " newborn expectorant ", pulverized 100-140 mesh sieve (preferred: to pulverize 110-130 mesh sieve in step (4); Be more preferably: pulverized 120 mesh sieves).
The pharmaceutical preparation of described treatment women " newborn expectorant ", be made into pharmaceutically acceptable thick paste, its preparation method is:
(1) get Nidus Vespae and clean removing impurity, toast under being placed in 180 DEG C of environment 8-16 minute (preferred, toast 12 minutes), be placed on immediately in vinegar liquid after taking-up and soak, pull out, drying, to pulverize;
(2) get after Flos Carthami cleans, add Chinese liquor, soaks 10-20 minute (preferred: immersion 12-18 minute; Be more preferably: soak 15 minutes), the steaming and decocting of sealing slow fire is to dry, and taking-up is dried;
(3) Hera lapsanae apogonoidis, Herba hyperici elodeoidis, Herba Taraxaci and Herba pteridis vittatae is clean, cutting, is placed in parch container, the micro-stir-fry of little fire 5 minutes, pulverizes after taking out together with step (1) (2) made crude drug, loads in bag filter;
(4) by Pericarpium Citri Reticulatae, Rhizoma Cyperi, Bulbus Fritillariae Cirrhosae, Radix Glycyrrhizae, Retinervus Luffae Fructus, rhizoma scirpi, the Rhizoma Anemarrhenae, Semen Lepidii (Semen Descurainiae) and Rhizoma Corydalis clear water drip washing moistening, be placed in together with bag filter in marmite, add water and do not have medical material 5cm, big fire is heated to boiling, turns little fire and decocts 30-50 minute (preferably: little fire decocts 35-45 minute; Be more preferably: little fire decocts 40 minutes), Guan Huo, filtration collect filtrate;
(5) by step (4) gained filtrate, heating is concentrated into paste, then mixs homogeneously with refined honey, obtains thick paste.
The preparation method of the pharmaceutical preparation thick paste of described treatment women " newborn expectorant ", in step (5), the amount of refined honey is the 0.2-0.4 of paste weight doubly (preferred: the amount of refined honey is 0.3 times of paste weight).
The pharmaceutical preparation of described treatment women " newborn expectorant ", be made into pharmaceutically acceptable tablet, its preparation method is:
(1) get Nidus Vespae and clean removing impurity, toast under being placed in 180 DEG C of environment 8-16 minute (preferred, toast 12 minutes), be placed on immediately in vinegar liquid after taking-up and soak, pull out, drying, to pulverize;
(2) get after Flos Carthami cleans, add Chinese liquor, soaks 10-20 minute (preferred: immersion 12-18 minute; Be more preferably: soak 15 minutes), the steaming and decocting of sealing slow fire is to dry, and taking-up is dried;
(3) by Pericarpium Citri Reticulatae, Rhizoma Cyperi, Bulbus Fritillariae Cirrhosae, Radix Glycyrrhizae, Retinervus Luffae Fructus, rhizoma scirpi, the Rhizoma Anemarrhenae, Semen Lepidii (Semen Descurainiae) and Rhizoma Corydalis clear water drip washing moistening, be placed in marmite, add water and do not have medical material 5cm, big fire is heated to boiling, turns little fire and decocts 30-50 minute (preferably: little fire decocts 35-45 minute; Be more preferably: little fire decocts 40 minutes), close fire first 15 minutes, then add clean Hera lapsanae apogonoidis, Herba hyperici elodeoidis, Herba Taraxaci and Herba pteridis vittatae, filtered while hot, collect filtrate;
(4) by step (3) gained filtrate spraying dry, pulverized 180 mesh sieves together with step (1) (2) gained crude drug, be crushed to circular tablets according to the preparation method of tablet, obtain tablet.
The preparation method of the pharmaceutical preparation tablet of described treatment women " newborn expectorant ", in step (4), the weight of tablet is 0.4-0.6g/ sheet (preferred: the weight of tablet is 0.5g/ sheet).
The pharmaceutical formulation science for the treatment of women " newborn expectorant " provided by the invention, preparation method is simple.In addition, its excellent part also shows:
1, medical material pure natural selected by the present invention, have no side effect, rationally process can play curative effect to greatest extent;
2, products obtained therefrom of the present invention has the effects such as clearing away heat-damp and promoting diuresis, promoting blood circulation and stopping pain, eliminating stasis and resolving masses;
3, this prescription can be made into multiple dosage form, stable effective ingredients, and cure rate is high, and the suitability is wide.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
embodiment 1the pharmaceutical preparation for the treatment of women " newborn expectorant ", is prepared from primarily of following bulk drugs, every part of 10g: Pericarpium Citri Reticulatae 10 parts, Hera lapsanae apogonoidis 3 parts, Rhizoma Cyperi 9 parts, Herba hyperici elodeoidis 6 parts, Bulbus Fritillariae Cirrhosae 10 parts, 8 parts, Radix Glycyrrhizae, 9 parts, Flos Carthami, Herba Taraxaci 10 parts, Nidus Vespae 10 parts, Retinervus Luffae Fructus 10 parts, rhizoma scirpi 9 parts, Herba pteridis vittatae 4 parts, the Rhizoma Anemarrhenae 8 parts, Semen Lepidii (Semen Descurainiae) 9 parts, Rhizoma Corydalis 5 parts.The preparation method of the pharmaceutical preparation decoction of above-mentioned treatment women " newborn expectorant " is:
(1) get Nidus Vespae and clean removing impurity, to be placed under 180 DEG C of environment baking 12 minutes, to be placed on immediately in vinegar liquid after taking-up and to soak, pull out, dry, pulverize;
(2) get after Flos Carthami cleans, add the Chinese liquor of crude drug weight 5 times, soaks 15 minutes, sealing slow fire steaming and decocting is to drying, and taking-up is dried;
(3) by Pericarpium Citri Reticulatae, Rhizoma Cyperi, Bulbus Fritillariae Cirrhosae, Radix Glycyrrhizae, Retinervus Luffae Fructus, rhizoma scirpi, the Rhizoma Anemarrhenae, Semen Lepidii (Semen Descurainiae) and Rhizoma Corydalis clear water drip washing moistening, be placed in marmite, add water and do not have medical material 5cm, big fire is heated to boiling, turn little fire to decoct 40 minutes, filter after closing fire, collect filtrate;
(4) Hera lapsanae apogonoidis, Herba hyperici elodeoidis, Herba Taraxaci and Herba pteridis vittatae is clean, cutting, is placed in parch container, the micro-stir-fry of little fire 5 minutes, pulverized 200 mesh sieves, and obtained medicated powder after taking out together with step (1) (2) made crude drug;
(5) by step (3) and (4) gained filtrate and medicated powder mix homogeneously, sterilizing encapsulates to obtain decoction.
embodiment 2the pharmaceutical preparation for the treatment of women " newborn expectorant ", is prepared from primarily of following bulk drugs, every part of 10g: Pericarpium Citri Reticulatae 15 parts, Hera lapsanae apogonoidis 6 parts, Rhizoma Cyperi 15 parts, Herba hyperici elodeoidis 9 parts, Bulbus Fritillariae Cirrhosae 16 parts, 15 parts, Radix Glycyrrhizae, 12 parts, Flos Carthami, Herba Taraxaci 20 parts, Nidus Vespae 20 parts, Retinervus Luffae Fructus 20 parts, rhizoma scirpi 15 parts, Herba pteridis vittatae 9 parts, the Rhizoma Anemarrhenae 16 parts, Semen Lepidii (Semen Descurainiae) 14 parts, Rhizoma Corydalis 10 parts.The preparation method of the pharmaceutical preparation powder of above-mentioned treatment women " newborn expectorant " is:
(1) get Nidus Vespae and clean removing impurity, to be placed under 180 DEG C of environment baking 12 minutes, to be placed on immediately in vinegar liquid after taking-up and to soak, pull out, dry, pulverize;
(2) get after Flos Carthami cleans, add Chinese liquor, soaks 15 minutes, sealing slow fire steaming and decocting is to drying, and taking-up is dried;
(3) by Pericarpium Citri Reticulatae, Rhizoma Cyperi, Bulbus Fritillariae Cirrhosae, Radix Glycyrrhizae, Retinervus Luffae Fructus, rhizoma scirpi, the Rhizoma Anemarrhenae, Semen Lepidii (Semen Descurainiae) and Rhizoma Corydalis clear water drip washing moistening, be placed in marmite, add water and do not have medical material 5cm, big fire is heated to boiling, turn little fire to decoct 40 minutes, close fire first 15 minutes, then add clean Hera lapsanae apogonoidis, Herba hyperici elodeoidis, Herba Taraxaci and Herba pteridis vittatae, filtered while hot, collects filtrate;
(4) by step (3) gained filtrate spraying dry, pulverized 120 mesh sieves together with step (1) (2) gained crude drug, encapsulated to obtain powder.
Model case: xxx, women, 34 years old.Main suit: right lump in breast 1 year, becomes large and pain gradually.Medical history: find that right breast has the hard Silent Neuritis lump of a matter, about niblet size, non-diagnosis and treatment the year before, lump becomes large gradually, forms cold pus infections, can extrude a small amount of pus, through hospital organization cut sections for microscopic examination, be diagnosed as tuberculosis of breast after softening.
Using this example gained powder, each 3-5g, one day three times, 8 days is a course for the treatment of, and after taking 15 days, lump reduces, and pus discharge declines, and continue two courses for the treatment of of use, the lump of patient is eliminated substantially, and wound heals substantially, and call on after 1 year, patient is not recurred.
embodiment 3the pharmaceutical preparation for the treatment of women " newborn expectorant ", is prepared from primarily of following bulk drugs, every part of 10g: Pericarpium Citri Reticulatae 11 parts, Hera lapsanae apogonoidis 4 parts, Rhizoma Cyperi 11 parts, Herba hyperici elodeoidis 7 parts, Bulbus Fritillariae Cirrhosae 12 parts, 10 parts, Radix Glycyrrhizae, 10 parts, Flos Carthami, Herba Taraxaci 12 parts, Nidus Vespae 12 parts, Retinervus Luffae Fructus 13 parts, rhizoma scirpi 11 parts, Herba pteridis vittatae 5 parts, the Rhizoma Anemarrhenae 10 parts, Semen Lepidii (Semen Descurainiae) 10 parts, Rhizoma Corydalis 6 parts.The preparation method of the pharmaceutical preparation thick paste of above-mentioned treatment women " newborn expectorant " is:
(1) get Nidus Vespae and clean removing impurity, to be placed under 180 DEG C of environment baking 12 minutes, to be placed on immediately in vinegar liquid after taking-up and to soak, pull out, dry, pulverize;
(2) get after Flos Carthami cleans, add Chinese liquor, soaks 15 minutes, sealing slow fire steaming and decocting is to drying, and taking-up is dried;
(3) Hera lapsanae apogonoidis, Herba hyperici elodeoidis, Herba Taraxaci and Herba pteridis vittatae is clean, cutting, is placed in parch container, the micro-stir-fry of little fire 5 minutes, pulverizes after taking out together with step (1) (2) made crude drug, loads in bag filter;
(4) by Pericarpium Citri Reticulatae, Rhizoma Cyperi, Bulbus Fritillariae Cirrhosae, Radix Glycyrrhizae, Retinervus Luffae Fructus, rhizoma scirpi, the Rhizoma Anemarrhenae, Semen Lepidii (Semen Descurainiae) and Rhizoma Corydalis clear water drip washing moistening, be placed in together with bag filter in marmite, add water and do not have medical material 5cm, big fire is heated to boiling, turn little fire to decoct 40 minutes, Guan Huo, filtration collect filtrate;
(5) by step (4) gained filtrate, heating is concentrated into paste, then mixs homogeneously with the refined honey of paste weight 0.3 times, obtains thick paste.
Model case: xxx, women, 29 years old.Medical history: patient has given birth to baby 1 year, realizes mammary swelling, has lump, nipple can extrude yellow milk and liquid, after examination by centesis, finds that there is caseous necrosis, be diagnosed as tuberculosis of breast, inject after three days cefoperzone sodium and sulbactam sodium add levofloxacin, effect is not remarkable.
People is listened to recommend Chinese medicine effect pretty good, housecoat this example gained thick paste, each 3-5g, one day three times, it within 8 days, is a course for the treatment of, after patient takes a course for the treatment of, obviously sensation swelling alleviates, and lump reduces gradually, after adhering to taking two courses for the treatment of, patient is almost recovered, and returns examination in hospital, and pathological section display is normal.
embodiment 4the pharmaceutical preparation for the treatment of women " newborn expectorant ", is prepared from primarily of following bulk drugs, every part of 10g: Pericarpium Citri Reticulatae 14 parts, Hera lapsanae apogonoidis 5 parts, Rhizoma Cyperi 13 parts, Herba hyperici elodeoidis 8 parts, Bulbus Fritillariae Cirrhosae 14 parts, 13 parts, Radix Glycyrrhizae, 11 parts, Flos Carthami, Herba Taraxaci 18 parts, Nidus Vespae 18 parts, Retinervus Luffae Fructus 17 parts, rhizoma scirpi 13 parts, Herba pteridis vittatae 8 parts, the Rhizoma Anemarrhenae 14 parts, Semen Lepidii (Semen Descurainiae) 13 parts, Rhizoma Corydalis 9 parts.The preparation method of the pharmaceutical preparation tablet of above-mentioned treatment women " newborn expectorant " is:
(1) get Nidus Vespae and clean removing impurity, to be placed under 180 DEG C of environment baking 12 minutes, to be placed on immediately in vinegar liquid after taking-up and to soak, pull out, dry, pulverize;
(2) get after Flos Carthami cleans, add Chinese liquor, soaks 15 minutes, sealing slow fire steaming and decocting is to drying, and taking-up is dried;
(3) by Pericarpium Citri Reticulatae, Rhizoma Cyperi, Bulbus Fritillariae Cirrhosae, Radix Glycyrrhizae, Retinervus Luffae Fructus, rhizoma scirpi, the Rhizoma Anemarrhenae, Semen Lepidii (Semen Descurainiae) and Rhizoma Corydalis clear water drip washing moistening, be placed in marmite, add water and do not have medical material 5cm, big fire is heated to boiling, turn little fire to decoct 40 minutes, close fire first 15 minutes, then add clean Hera lapsanae apogonoidis, Herba hyperici elodeoidis, Herba Taraxaci and Herba pteridis vittatae, filtered while hot, collects filtrate;
(4) by step (3) gained filtrate spraying dry, pulverized 180 mesh sieves together with step (1) (2) gained crude drug, be crushed to circular tablets according to the preparation method of tablet, obtained the tablet that weight is 0.5g/ sheet.
Model case: xxx, women, 45 years old.Medical history: patient is mastalgia the year before, dare not touch, find that there is lump subsequently, locally rubescent, heating, nipple starts depression, yellowish-brown troubled liquor can be extruded, remove examination in hospital, find the enlargement of left oxter, lymph node merges agglomerating, matter is hard, boundary owes clear, through the biopsy of left newborn hollow needle puncturing tissue, is diagnosed as tuberculosis of breast.
Because using antituberculotics irritated, under the suggestion of doctor, take the treatment of this example gained Chinese medicinal tablet, one time 4, one day three times 8 days is a course for the treatment of, after patient takes one week, mastalgia alleviates, and uncomfortable disease alleviates, take two courses for the treatment of continuously, lump disappears, and suppurative liquid is substantially clean, consolidate again a course for the treatment of, patient fully recovers, further consultation inspection, all normally.
embodiment 5the pharmaceutical preparation for the treatment of women " newborn expectorant ", is prepared from primarily of following bulk drugs, every part of 10g: Pericarpium Citri Reticulatae 12.5 parts, Hera lapsanae apogonoidis 4.5 parts, Rhizoma Cyperi 12 parts, Herba hyperici elodeoidis 7.5 parts, Bulbus Fritillariae Cirrhosae 13 parts, 11.5 parts, Radix Glycyrrhizae, 10.5 parts, Flos Carthami, Herba Taraxaci 15 parts, Nidus Vespae 15 parts, Retinervus Luffae Fructus 15 parts, rhizoma scirpi 12 parts, Herba pteridis vittatae 6.5 parts, the Rhizoma Anemarrhenae 12 parts, Semen Lepidii (Semen Descurainiae) 11.5 parts, Rhizoma Corydalis 7.5 parts.The preparation method of the pharmaceutical preparation decoction of above-mentioned treatment women " newborn expectorant " is:
(1) get Nidus Vespae and clean removing impurity, to be placed under 180 DEG C of environment baking 12 minutes, to be placed on immediately in vinegar liquid after taking-up and to soak, pull out, dry, pulverize;
(2) get after Flos Carthami cleans, add the Chinese liquor of crude drug weight 5 times, soaks 15 minutes, sealing slow fire steaming and decocting is to drying, and taking-up is dried;
(3) by Pericarpium Citri Reticulatae, Rhizoma Cyperi, Bulbus Fritillariae Cirrhosae, Radix Glycyrrhizae, Retinervus Luffae Fructus, rhizoma scirpi, the Rhizoma Anemarrhenae, Semen Lepidii (Semen Descurainiae) and Rhizoma Corydalis clear water drip washing moistening, be placed in marmite, add water and do not have medical material 5cm, big fire is heated to boiling, turn little fire to decoct 40 minutes, filter after closing fire, collect filtrate;
(4) Hera lapsanae apogonoidis, Herba hyperici elodeoidis, Herba Taraxaci and Herba pteridis vittatae is clean, cutting, is placed in parch container, the micro-stir-fry of little fire 5 minutes, pulverized 200 mesh sieves, and obtained medicated powder after taking out together with step (1) (2) made crude drug;
(5) by step (3) and (4) gained filtrate and medicated powder mix homogeneously, sterilizing encapsulates to obtain decoction.
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
Pericarpium Citri Reticulatae: nature and flavor with return through: bitter, pungent, temperature.Return lung, spleen channel.There is regulating qi-flowing for strengthening spleen, effect of drying dampness to eliminate phlegm.For distension and fullness in the abdomen, lack of appetite and vomiting, cough with copious phlegm.
Hera lapsanae apogonoidis: base is former: be the herb of section of district plant Hera lapsanae apogonoidis.Nature and flavor: bitter in the mouth; Property is put down.Function cures mainly: heat-clearing and toxic substances removing; Rash.Main laryngopharynx swelling and pain; Dysentery; Sore swollen toxin; Venom; Measles is sent out not smooth thoroughly.
Rhizoma Cyperi: base is former: be the rhizome of sedge dried tuber.Nature and flavor with return through: pungent, micro-hardship, micro-sweet, flat.Return liver, spleen, tri-jiao channel.There is dispersing the stagnated live-QI to relieve the stagnation of QI, regulating the flow of QI to ease the stomach, effect of menstruction regulating and pain relieving.For stagnation of QI due to depression of the liver, distending pain in the chest and hypochondrium, hernia pain, distending pain of the breast, stagnation of QI in spleen and stomach, gastral cavity abdomen painful abdominal mass is vexed, distension pain, menoxenia, amenorrhea dysmenorrhea.
Herba hyperici elodeoidis: base is former: be the Herb of Garcinia maingayii Herba hyperici elodeoidis.Nature and flavor: cold; Bitter; Puckery.Gui Jing: large intestine channel.Function cures mainly: heat-clearing and toxic substances removing; Antidiarrheal.Main infantile whitish aphthae; Infantile pneumonia; Stomatitis; Mastalgia; Impetigo; Venom; Diarrhoea; Chronic dysentery.
Bulbus Fritillariae Cirrhosae: base is former: be the bulb of liliaceous plant Fritillaria Cirrhosa D. Don, crow flower Bulbus Fritillariae Uninbracteatae or rib sand Bulbus Fritillariae Uninbracteatae etc.Nature and flavor: bitter sweet, cool.Gui Jing: enter lung meridian.Function cures mainly: lung moistening eliminating stagnation, antitussive reduces phlegm.Control cough due to consumptive disease, spitting of blood of spitting, ambition pent-up, consumptive lung disease, lung abscess, goiter, honest and clean scrofula, sore throat, acute mastitis.
Radix Glycyrrhizae: base is former: be the Root and Rootstock of pulse family glycyrrhiza genus Radix Glycyrrhizae.Nature and flavor: sweet are flat.Gui Jing: enter spleen, stomach, lung meridian.Function cures mainly: with middle emergency, lung moistening, removing toxic substances, coordinating the actions of various ingredients in a prescription.Process use, control weakness of the spleen and stomach, lack of appetite, stomachache loose stool, overstrain generates heat, and consumptive lung disease is coughed, cardiopalmus, infantile convulsion; Raw use, controls laryngopharynx swelling and pain, peptic ulcer, ulcer sores, separates poison of drug and alimentary toxicosis.
Flos Carthami: base is former: Compositae, Flos Carthami platymiscium, dry tubular flower, orange red.Chemical composition: containing carthamone, neocarthamin, saffloside, Carthamus yellow and flavochrome.Another containing safflower oil, oil comprises Palmic acid, myristic acid, lauric acid, stearic acid, arachidic acid, oleic acid etc.Pharmacological action: the effect having slight excited heart, reduce coronary resistance, increase coronary flow and cardiac muscle nutritional blood flow; Protect and improve myocardial ischemia, reducing myocardial infarct size; Reddish yellow pigment separator can to arrhythmia; Decoct, Aqueous extracts, Carthamus yellow etc. can be expanded peripheral vessels, reduce blood pressure.Energy anticoagulant, fortifying fibre protein dissolution, reduces whole blood viscosity.Injection, ethanol extract, saffloside can significantly improve hypoxia-bearing capability, have protective effect to the weary oxygen encephalopathy of ischemia.Nature and flavor with return through: pungent, temperature.GUIXIN, Liver Channel.There is effect of promoting blood circulation to restore menstrual flow, stasis-dispelling and pain-killing.For controlling amenorrhea, lump in the abdomen, difficult labour, stillborn fetus, disease that postpartum lochia can't go, blood stasis are had a pain, carbuncle, injury from falling down.
Herba Taraxaci: nature and flavor with return through: bitter, sweet, cold.Return liver, stomach warp.Function with cure mainly: heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, inducing diuresis for treating stranguria syndrome.For furuncle swelling toxin, acute mastitis, scrofula, conjunctival congestion, pharyngalgia, lung abscess, acute appendicitis, jaundice due to damp-heat, the puckery pain of pyretic stranguria.
Nidus Vespae: base is former: be Vespidae insecticide hornet or the nest belonging to nearly edge insecticide together.Nature and flavor: sweet are flat, poisonous.Gui Jing: 1. " detailed outline ": " enter Yangming Channel." 2. " book on Chinese herbal medicine is new again ": " enters liver, lung two warp." function cures mainly: dispel the wind, counteracting toxic substances, parasite killing.Control infantile convulsion, migratory arthralgia, urticaria pruritus, acute mastitis, furunculosis, scrofula, anal fistula, acute toothache, tinea capitis, honeybee stings swollen pain.
Retinervus Luffae Fructus: base is former: be the reticular fiber of the old hot fruit of cucurbitaceous plant Fructus Luffae or the withered old fruit of Guangdong Fructus Luffae.Chemical analysis: Retinervus Luffae Fructus, containing xylan and cellulose, also may contain mannan, galactan and lignin etc.Nature and flavor: sweet are flat.Function cures mainly: dredge the meridian passage, removing heat-phlegm.Control pain in chest and hypochondrium, stomachache, lumbago, painful and swollen testis, lung-heat productive cough, women's amenorrhea, galactostasis, carbuncle, anal fistula.Charcoal: can stop blooding.Treating hematochezia, metrorrhagia.
Rhizoma scirpi: base is former: be the tuber of sedge cyperus iria L. rhizoma scirpi.Chemical analysis: containing betulin and mannitol.Nature and flavor: acrid in the mouth; Bitter; Property is put down.Gui Jing: liver; Spleen channel.Function cures mainly: blood stasis dispelling stimulates the menstrual flow; Removing blood stasis eliminating mass; Circulation of qi promoting removing food stagnancy.Main amenorrhea due to stagnation of blood; Dysmenorrhea; Postpartum stagnation is suffered from abdominal pain; Traumatic injury congestive edema; Enclosed mass in abdomen; Abdominal pain due to retention of food.
Herba pteridis vittatae: base is former: be herb or the rhizome of Pteridaceae plant Herba pteridis vittatae.Chemical analysis: herb is containing lignan's glycoside, and cis-dihydro-dehydrodiconiferylalcohol-9-O-β-D-Glucose glycoside, lariciresinol-9-O-β-D-Glucose glycoside, also containing diacylglycerol base trimethyl homoserine.Nature and flavor: light; Bitter; Cool.Gui Jing: liver; Large intestine; Urinary bladder channel.Function cures mainly: expelling wind and removing dampness; Relaxing muscles and tendons and activating QI and blood in the collateral; Removing toxic substances parasite killing.Main air wets bones and muscles pain; Lumbago; Limb fiber crops joint stuffiness; Hemiplegia; Traumatic injury; Flu; Dysentery; Acute mastitis; Sore; Scabies; Ascariasis; Serpentis is early bitten.
The Rhizoma Anemarrhenae: nature and flavor: bitter, sweet, cold.Return lung, stomach, kidney channel.There is clearing away heat-fire, nourshing Yin and drynsessmoistening prescription effect.For fever caused by exogenous pathogenic factors, high hot excessive thirst, lung-heat type cough, osteopyrexia and fever, interior-heat is quenched one's thirst, dryness of the intestine constipation.
Semen Lepidii (Semen Descurainiae): base is former: be the seed of crucifer Lepidium sativum L., North America semolina or descurainia sophia (l.) webb ex prantl.Chemical analysis: the fatty oil of Lepidium sativum L. seed, sinigrin, protein, saccharide.Nature and flavor: arduous, cold.Gui Jing: enter lung, urinary bladder channel.Function cures mainly: therapeutic method to keep the adverse QI flowing downwards row water.Control lung and stop up dyspnea with rapid respiration, expectorant bank is coughed, edema distension.
Rhizoma Corydalis: base is former: be the tuber of papaveraceae plant corydalis.Nature and flavor: arduous, temperature.Gui Jing: enter liver, stomach warp.Function cures mainly: invigorate blood circulation, and dissipating blood stasis is regulated the flow of vital energy, pain relieving.Control all pains of trusted subordinate's waist knee joint, menoxenia, lump in the abdomen, metrorrhagia, puerperal blood faints, lochiorrhea, traumatic injury.
test example 1the clinical practice of the pharmaceutical preparation (embodiment 5) of gained treatment women " newborn expectorant " of the present invention:
Choose crowd: according to the idagnostic logout of hospital Galactophore Dept., screening suffers from patient 359 example of tuberculosis of breast, the range of age 20-70 year, the mean age is 38.9 years old, the shortest 25 days of the course of disease, the longest 2 years, 49 wherein unmarried examples, 310 married examples.Diagnostic criteria: in (1) mammary gland, Silent Neuritis lump or cold abscess are formed, forms sinus tract or ulcer that prolonged difficulty heals after ruptured abscess; (2) diseases such as breast carcinoma, cyclomastopathy, mammary gland fibroma and chronic inflammatory enclosed mass are got rid of; (3) confirm through check pathological section.
Before test, patient is divided into two groups at random, experimental group 240 example and matched group 119 routine, two groups in age, the course of disease, the state of an illness etc. without significant difference.Experimental group takes gained decoction of the present invention, each 30-50ml, every day three times, warmly takes, and within 8 days, is a course for the treatment of; Matched group takes other conventional medicines (isoniazid, rifampicin or ethambutol etc.).Period in a medicine carries out Continuous Observation to two groups of patients, record symptom and change.
Curative effect determinate standard: reference literature criterion of therapeutical effect, (1) cures: uncomfortable disease is eliminated, and lump in breast disappears, ulcer and sinus tract healing, and the state of an illness does not recur; (2) effective: uncomfortable disease is obviously improved, and mammary gland tumor reduces, ulcer, sinus tract are close to healing; (3) invalid: uncomfortable disease and lump unchanged or increase the weight of.
Clinical effectiveness: after the taking medicine of three courses for the treatment of, use in the experimental group of products obtained therefrom of the present invention, curing number of cases is 183 examples (cure rates 76.3%), and effective number of cases is 51 examples (effective percentage 21.2%), invalid number of cases is 6 examples (inefficiencies 2.5), and the total effective rate of known experimental group is 97.5%.The patient cured in matched group has 64 examples (cure rate 53.8%), and the improved effective patient of symptom has 23(effective percentage 19.3%), the total effective rate of matched group is 73.1%.Experimental group product curative effect used is obviously better than matched group, and treatments period, all there is not untoward reaction in patient, indices inspection is normal.
The Chinese medicine used in the present invention, the wherein regulating qi-flowing for strengthening spleen of Pericarpium Citri Reticulatae, the heat-clearing and toxic substances removing of Hera lapsanae apogonoidis, the menstruction regulating and pain relieving of Rhizoma Cyperi, the heat-clearing and toxic substances removing of Herba hyperici elodeoidis, the lung moistening eliminating stagnation of Bulbus Fritillariae Cirrhosae, the lung moistening removing toxic substances of Radix Glycyrrhizae, the promoting blood circulation to restore menstrual flow of Flos Carthami, the dispersing swelling and dissipating binds of Herba Taraxaci, the counteracting toxic substances that dispels the wind of Nidus Vespae, the dredge the meridian passage of Retinervus Luffae Fructus, the blood stasis dispelling of rhizoma scirpi stimulates the menstrual flow, the relaxing muscles and tendons and activating QI and blood in the collateral of Herba pteridis vittatae, the clearing away heat-fire of the Rhizoma Anemarrhenae, the therapeutic method to keep the adverse QI flowing downwards row water of Semen Lepidii (Semen Descurainiae), the promoting blood circulation to remove blood stasis of Rhizoma Corydalis, all medicines share, soothing the liver eliminating the phlegm can be reached, effect of promoting blood circulation to remove obstruction in the collateral, thus raising therapeutic effect, recovery patient body is healthy.
It should be pointed out that detailed description of the invention is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clear and definite disclosed or according to undoubted the obtaining of the written description of file, the claimed scope of this patent all should be thought.

Claims (10)

1. treat the pharmaceutical preparation of women's " newborn expectorant ", it is characterized in that, be prepared from primarily of following bulk drugs, be weight portion: Pericarpium Citri Reticulatae 10-15; Hera lapsanae apogonoidis 3-6; Rhizoma Cyperi 9-15; Herba hyperici elodeoidis 6-9; Bulbus Fritillariae Cirrhosae 10-16; Radix Glycyrrhizae 8-15; Flos Carthami 9-12; Herba Taraxaci 10-20; Nidus Vespae 10-20; Retinervus Luffae Fructus 10-20; Rhizoma scirpi 9-15; Herba pteridis vittatae 4-9; Rhizoma Anemarrhenae 8-16; Semen Lepidii (Semen Descurainiae) 9-14; Rhizoma Corydalis 5-10.
2. treat the pharmaceutical preparation of women's " newborn expectorant " as claimed in claim 1, it is characterized in that, Pericarpium Citri Reticulatae 11-14; Hera lapsanae apogonoidis 4-5; Rhizoma Cyperi 11-13; Herba hyperici elodeoidis 7-8; Bulbus Fritillariae Cirrhosae 12-14; Radix Glycyrrhizae 10-13; Flos Carthami 10-11; Herba Taraxaci 12-18; Nidus Vespae 12-18; Retinervus Luffae Fructus 13-17; Rhizoma scirpi 11-13; Herba pteridis vittatae 5-8; Rhizoma Anemarrhenae 10-14; Semen Lepidii (Semen Descurainiae) 10-13; Rhizoma Corydalis 6-9(is preferably: Pericarpium Citri Reticulatae 12.5; Hera lapsanae apogonoidis 4.5; Rhizoma Cyperi 12; Herba hyperici elodeoidis 7.5; Bulbus Fritillariae Cirrhosae 13; Radix Glycyrrhizae 11.5; Flos Carthami 10.5; Herba Taraxaci 15; Nidus Vespae 15; Retinervus Luffae Fructus 15; Rhizoma scirpi 12; Herba pteridis vittatae 6.5; The Rhizoma Anemarrhenae 12; Semen Lepidii (Semen Descurainiae) 11.5; Rhizoma Corydalis 7.5).
3. the pharmaceutical preparation of the treatment women " newborn expectorant " as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable decoction, its preparation method is:
(1) get Nidus Vespae and clean removing impurity, toast under being placed in 180 DEG C of environment 8-16 minute (preferred, toast 12 minutes), be placed on immediately in vinegar liquid after taking-up and soak, pull out, drying, to pulverize;
(2) get after Flos Carthami cleans, add Chinese liquor, soaks 10-20 minute (preferred: immersion 12-18 minute; Be more preferably: soak 15 minutes), the steaming and decocting of sealing slow fire is to dry, and taking-up is dried;
(3) by Pericarpium Citri Reticulatae, Rhizoma Cyperi, Bulbus Fritillariae Cirrhosae, Radix Glycyrrhizae, Retinervus Luffae Fructus, rhizoma scirpi, the Rhizoma Anemarrhenae, Semen Lepidii (Semen Descurainiae) and Rhizoma Corydalis clear water drip washing moistening, be placed in marmite, add water and do not have medical material 5cm, big fire is heated to boiling, turns little fire and decocts 30-50 minute (preferably: little fire decocts 35-45 minute; Be more preferably: little fire decocts 40 minutes), filter after closing fire, collect filtrate;
(4) Hera lapsanae apogonoidis, Herba hyperici elodeoidis, Herba Taraxaci and Herba pteridis vittatae is clean, cutting, is placed in parch container, the micro-stir-fry of little fire 5 minutes, pulverizes 180-220 mesh sieve (preferred: to pulverize 190-210 mesh sieve after taking out together with step (1) (2) made crude drug; Be more preferably: pulverized 200 mesh sieves), obtain medicated powder;
(5) by step (3) and (4) gained filtrate and medicated powder mix homogeneously, sterilizing encapsulates to obtain decoction.
4. treat the preparation method of the pharmaceutical preparation decoction of women's " newborn expectorant " as claimed in claim 3, it is characterized in that, the amount adding Chinese liquor in step (2) is the 4-6 of crude drug weight doubly (preferred: the amount adding Chinese liquor is 5 times of crude drug weight).
5. the pharmaceutical preparation of the treatment women " newborn expectorant " as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable powder, its preparation method is:
(1) get Nidus Vespae and clean removing impurity, toast under being placed in 180 DEG C of environment 8-16 minute (preferred, toast 12 minutes), be placed on immediately in vinegar liquid after taking-up and soak, pull out, drying, to pulverize;
(2) get after Flos Carthami cleans, add Chinese liquor, soaks 10-20 minute (preferred: immersion 12-18 minute; Be more preferably: soak 15 minutes), the steaming and decocting of sealing slow fire is to dry, and taking-up is dried;
(3) by Pericarpium Citri Reticulatae, Rhizoma Cyperi, Bulbus Fritillariae Cirrhosae, Radix Glycyrrhizae, Retinervus Luffae Fructus, rhizoma scirpi, the Rhizoma Anemarrhenae, Semen Lepidii (Semen Descurainiae) and Rhizoma Corydalis clear water drip washing moistening, be placed in marmite, add water and do not have medical material 5cm, big fire is heated to boiling, turns little fire and decocts 30-50 minute (preferably: little fire decocts 35-45 minute; Be more preferably: little fire decocts 40 minutes), close fire first 15 minutes, then add clean Hera lapsanae apogonoidis, Herba hyperici elodeoidis, Herba Taraxaci and Herba pteridis vittatae, filtered while hot, collect filtrate;
(4) by step (3) gained filtrate spraying dry, pulverize together with step (1) (2) gained crude drug, encapsulate to obtain powder.
6. treat the preparation method of the pharmaceutical preparation powder of women's " newborn expectorant " as claimed in claim 5, it is characterized in that, pulverize 100-140 mesh sieve in step (4) (preferred: to pulverize 110-130 mesh sieve; Be more preferably: pulverized 120 mesh sieves).
7. the pharmaceutical preparation of the treatment women " newborn expectorant " as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable thick paste, its preparation method is:
(1) get Nidus Vespae and clean removing impurity, toast under being placed in 180 DEG C of environment 8-16 minute (preferred, toast 12 minutes), be placed on immediately in vinegar liquid after taking-up and soak, pull out, drying, to pulverize;
(2) get after Flos Carthami cleans, add Chinese liquor, soaks 10-20 minute (preferred: immersion 12-18 minute; Be more preferably: soak 15 minutes), the steaming and decocting of sealing slow fire is to dry, and taking-up is dried;
(3) Hera lapsanae apogonoidis, Herba hyperici elodeoidis, Herba Taraxaci and Herba pteridis vittatae is clean, cutting, is placed in parch container, the micro-stir-fry of little fire 5 minutes, pulverizes after taking out together with step (1) (2) made crude drug, loads in bag filter;
(4) by Pericarpium Citri Reticulatae, Rhizoma Cyperi, Bulbus Fritillariae Cirrhosae, Radix Glycyrrhizae, Retinervus Luffae Fructus, rhizoma scirpi, the Rhizoma Anemarrhenae, Semen Lepidii (Semen Descurainiae) and Rhizoma Corydalis clear water drip washing moistening, be placed in together with bag filter in marmite, add water and do not have medical material 5cm, big fire is heated to boiling, turns little fire and decocts 30-50 minute (preferably: little fire decocts 35-45 minute; Be more preferably: little fire decocts 40 minutes), Guan Huo, filtration collect filtrate;
(5) by step (4) gained filtrate, heating is concentrated into paste, then in refined honey mix homogeneously, obtains thick paste.
8. treat the preparation method of the pharmaceutical preparation thick paste of women's " newborn expectorant " as claimed in claim 7, it is characterized in that, in step (5), the amount of refined honey is the 0.2-0.4 of paste weight doubly (preferred: the amount of refined honey is 0.3 times of paste weight).
9. the pharmaceutical preparation of the treatment women " newborn expectorant " as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable tablet, its preparation method is:
(1) get Nidus Vespae and clean removing impurity, toast under being placed in 180 DEG C of environment 8-16 minute (preferred, toast 12 minutes), be placed on immediately in vinegar liquid after taking-up and soak, pull out, drying, to pulverize;
(2) get after Flos Carthami cleans, add Chinese liquor, soaks 10-20 minute (preferred: immersion 12-18 minute; Be more preferably: soak 15 minutes), the steaming and decocting of sealing slow fire is to dry, and taking-up is dried;
(3) by Pericarpium Citri Reticulatae, Rhizoma Cyperi, Bulbus Fritillariae Cirrhosae, Radix Glycyrrhizae, Retinervus Luffae Fructus, rhizoma scirpi, the Rhizoma Anemarrhenae, Semen Lepidii (Semen Descurainiae) and Rhizoma Corydalis clear water drip washing moistening, be placed in marmite, add water and do not have medical material 5cm, big fire is heated to boiling, turns little fire and decocts 30-50 minute (preferably: little fire decocts 35-45 minute; Be more preferably: little fire decocts 40 minutes), close fire first 15 minutes, then add clean Hera lapsanae apogonoidis, Herba hyperici elodeoidis, Herba Taraxaci and Herba pteridis vittatae, filtered while hot, collect filtrate;
(4) by step (3) gained filtrate spraying dry, pulverized 180 mesh sieves together with step (1) (2) gained crude drug, be crushed to circular tablets according to the preparation method of tablet, obtain tablet.
10. treat the preparation method of the pharmaceutical preparation tablet of women's " newborn expectorant " as claimed in claim 9, it is characterized in that, in step (4), the weight of tablet is 0.4-0.6g/ sheet (preferred: the weight of tablet is 0.5g/ sheet).
CN201510027221.2A 2015-01-20 2015-01-20 Medicinal preparation for treating mammary sclerosis of women and preparation method thereof Pending CN104623453A (en)

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WO2002078727A1 (en) * 2001-01-26 2002-10-10 Van De Wiel Adriaan Emanuel He Medicinal and cosmetic use of hop and co-enzyme q10
CN102380083A (en) * 2011-11-15 2012-03-21 梁淑花 External plaster for treating mammary gland hyperplasia and lactation mastitis

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