CN104623135A - Liver-fire flaming treating drug and preparation method of oral liver-fire flaming treating drug micropills - Google Patents
Liver-fire flaming treating drug and preparation method of oral liver-fire flaming treating drug micropills Download PDFInfo
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Abstract
The invention relates to a liver-fire flaming treating drug, wherein the traditional Chinese medicine composition comprises the following bulk drugs by weight: 10-30 parts of gentiana scabra bunge, 1-30 parts of cape jasmine, 5-30 parts of scutellaria baicalensis georgi, 10-30 parts of radix bupleuri, 5-20 parts of angelica, 10-20 parts of rehmannia glutinosa libosch, 1-20 parts of caulis akebiae, 1-30 parts of alisma orientalis, 1-20 parts of rheum palmatum, and 1-20 parts of licorice root. According to the present invention, the drug with characteristics of low production cost, significant treatment effect and hepatitis excessive internal heat treating is provided; based on the liver-fire flaming caused by strong liver fire, liver damage, pathogenic fire derived from stagnation of liver-qi, pathogen heat invasion and internal heat generating, the drug of the present invention performs the specific and targeted medication, various drugs are supplemented and complemented each other, various bulk drugs are mutually coordinated and matched to achieve the optimal treatment effect, and the process of the preparation method of the oral liver-fire flaming treating drug micropills is simple.
Description
Technical field
The invention belongs to a kind of Chinese medicine, specifically belong to the treatment medicine of flaming up of liver-fire and the preparation method of oral micropill thereof
.
Background technology
Autumn and winter dry weather hydropenia, the health of people also there will be the symptom of some discomforts, and hot-tempered is exactly very common in winter.High liver fire is a kind of state of subhealth state, usually all can with some obvious symptoms, and the normal physiological affecting people is healthy, and the words that situation is very not serious can be alleviated by following dietetic therapy, if situation is too serious, advises seeking medical attention.Winter is easily hot-tempered, and be that adult or person of low position likely infect, the symptom of high liver fire easily appears in hepatitis B patient especially, has a strong impact on normal physiological health.The people of high liver fire, easy lassitude, feels dizzy distending pain, flushed face with red ears, the explosive irritability of emotion.Daytime, spirit was poor, easily dozed off, and dizzy, feeling of fatigue is obvious; Evening, sleep quality was not high, easily insomnia, dreaminess, woke up with a start.Emotion is easily affected, and upsets, and loses control of temper, easy on the trigger, get up morning there will be xerostomia, bitter taste, tongue fur are sent out thick, gingival swelling and pain etc.The hot-tempered distinguished gathering of women shows as menoxenia, through oligemia, delay menstrual period or amenorrhea etc.
The traditional Chinese medical science thinks the cause of disease of flaming up of liver-fire disease: how because feelings will is smooth, be worried angry, fire syndrome caused by overaction of the five emotions, makes liver-fire contain, or direct stimulation suddenly, damage edema with the liver involved, life in fire of moxibustion, or constitution with overabundance of YANG usually, and susceptible pathogenic heat, internal injury is in liver, and the fire of priming Liver Channel, follows through upper inflammation.Do not have the Western medicine that special for treating hepatitis is got angry at present, the Therapeutic Method of Chinese medicine is generally decoction, rarely found as oral liquid easy to carry, micropill class medicine.
Chinese medicine pellet has good looking appearance, good fluidity, and content of dispersion is large, and taking dose is little, and release is evenly reliable and stable, and specific surface area is large, and stripping is fast, and bioavailability is high.At present, micropill uses more and more in slow, controlled release preparation, therefore deeply likes by consumers in general.And have and take, carry, convenient transportation, not easily the moisture absorption, the advantages such as easy storage and custody.
Summary of the invention
Main and the inherent cause that the present invention gets angry according to hepatitis, and the advantage of micropill medicine, the invention provides the medicine that a kind of production cost is low, evident in efficacy, treatment hepatitis is got angry, and technique simply prepares the method for this oral micropill.
To achieve these goals, the technical solution used in the present invention is: the medicine for the treatment of flaming up of liver-fire, and this Chinese medicine composition is made up of the crude drug of following weight portion: Radix Gentianae 10-30 part, Fructus Gardeniae 1-30 part, Radix Scutellariae 5-30 part, Radix Bupleuri 10-30 part, Radix Angelicae Sinensis 5-20 part, Radix Rehmanniae 10-20 part, Caulis Akebiae 1-20 part, Rhizoma Alismatis 1-30 part, Radix Et Rhizoma Rhei 1-20 part, Radix Glycyrrhizae 1-20 part.
The weight portion of each crude drug of described Chinese medicine composition is: Radix Gentianae 15 parts, Fructus Gardeniae 10 parts, Radix Scutellariae 10 parts, Radix Bupleuri 10 parts, Radix Angelicae Sinensis 10 parts, 12 parts, the Radix Rehmanniae, Caulis Akebiae 10 parts, Rhizoma Alismatis 6 parts, Radix Et Rhizoma Rhei 6 parts, 6 parts, Radix Glycyrrhizae.
The preparation method of the drug oral micropill for the treatment of flaming up of liver-fire, concrete steps are as follows:
A, crude drug process, by Radix Gentianae, Fructus Gardeniae, Radix Scutellariae, Radix Bupleuri, Radix Angelicae Sinensis, the Radix Rehmanniae, Caulis Akebiae, Rhizoma Alismatis, Radix Et Rhizoma Rhei, Radix Glycyrrhizae is cleaned, oven dry, reprocesses in flakes or section, is then milled into fine powder with pulverizer respectively, crosses 100-200 object sieve, obtains standby material;
B, mixing pill, add binding agent by the standby material in step a and obtain plasticity soft material, soft material is inserted molding machine and prepares micropill, micropill is inserted microwave dryer drying;
C, coating of pellets, the micropill coating solution obtained by step b carries out coating, and dry after coating, the oral dose per diem taking two or three times carries out evacuation pack.
Described binding agent be syrup, sticky rice juice, 5 ~ 20% mucialga of arabic gummy or Resina persicae slurry.
Described coating solution is Lac or cellulose acetate-phthalate.
The weight portion of above-described crude drug can with a gram calculating.
In the present invention, the pharmacological property of each raw material is as follows:
Radix Gentianae: nature and flavor are bitter, puckery, Great Cold.Return liver, gallbladder meridian.Effect: heat clearing and damp drying, eliminating pathogen in the liver gallbladder fire.For jaundice due to damp-heat, swelling of the vulva pudendal pruritus, leukorrhagia, persistent erection of the penis, eczema pruritus, conjunctival congestion, deaf, hypochondriac pain, bitter taste, convulsion with spasms.
Fructus Gardeniae: cold in nature, sweet-bitter flavor.Return lung, Liver Channel.Clearing away heat and cooling blood Flos Gardeniae bitter cold, able person's blood system and clear pathogen is warm is pyogenic infections from tumour or sore, hemorrhoidal hamorrhage dysentery, the auxiliary treatment of the diseases such as bleeding due to blood-heat, effect of preventing phlegm from forming and stopping coughing, wide intestinal relieving constipation, the prevention outbreak of hemorrhoid and the generation of rectum carcinoma.
Radix Scutellariae: bitter, cold.Return lung, gallbladder, spleen, large intestine, small intestine meridian.Heat clearing and damp drying, eliminating fire and detoxication, hemostasis, antiabortive.For hygropyrexia, fever disease in summer vomiting and nausea uncomfortable in chest, damp and hot feeling of fullness, dysentery, jaundice, cough due to lung-heat, high hot excessive thirst, heat in blood tells nosebleed, carbuncle sore tumefacting virus, frequent fetal movement.
Radix Bupleuri: bitter in the mouth, cold nature.Return liver, gallbladder meridian.Evacuation is had to bring down a fever, soothing liver-QI, the function of yang invigorating.For cold, fever, alternate attack of chill and fever, malaria, distending pain in the chest and hypochondrium, menoxenia, uterine prolapse, the diseases such as proctoptosis.Recent studies is used for treating influenza virus, tubercule bacillus, disease caused by plasmodium.
Radix Angelicae Sinensis: warm in nature, sweet in the mouth is pungent.GUIXIN, liver, spleen channel.Benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturizes laxation.Control menoxenia, amenorrhea is suffered from abdominal pain, and lump in the abdomen knot is poly-, metrorrhagia; Headache due to deficiency of blood, dizzy, flaccidity syndrome and arthralgia syndrome; Dryness of the intestine dyschezia is heavy after bloody dysentery; Carbuncle skin ulcer steal, injury from falling down, strengthen immunity, antiinflammatory, protect the liver, radioprotective, antioxidation and scavenging free radicals etc.
The Radix Rehmanniae: sweet in the mouth, hardship, cold.GUIXIN, liver, kidney channel.Effect: sweet-bitter flavor, cold in nature and enter blood system, clearing away heat and cooling blood, Radix Rehmanniae clearing away heat and promoting production of body fluid, removing heat from blood, hemostasis.For consumption of YIN caused by febrile disease, crimson tongue excessive thirst, sends out speckle dermexanthesis, spits blood, epistaxis, laryngopharynx swelling and pain.Radix Rehmanniae clearing away heat and cooling blood, yin nourishing, promotes the production of body fluid.For calentura crimson tongue excessive thirst, yin asthenia generating intrinsic heat, hectic fever due to YIN-deficiency consumptive fever, interior-heat is quenched one's thirst, and spits blood, and epistaxis sends out speckle dermexanthesis.
Caulis Akebiae: bitter in the mouth, cold in nature.Enter heart channel, small intestine meridian, urinary bladder channel.Effect: clearing away heart-fire, diuresis, stimulating milk secretion of stimulating the menstrual flow.For irritable feverish sensation in the chest, sore throat pharyngalgia, dark coloured urine, five types of stranguria, edema, whole body spasm and pain, amenorrhea breast is few.Clearing away heat and promoting diuresis; Blood circulation and channel invigorating.Main red urine is red; Stranguria with turbid discharge; Edema; Irritable feverish sensation in the chest; Larynx larynx pain; Aphtha of the mouth and tongue; Rheumatic arthralgia; Galactostasis; Amenorrhea; Dysmenorrhea.
Rhizoma Alismatis: sweet in the mouth, cold in nature.Return kidney, urinary bladder channel.Effect: for dysuria, the diseases such as edema, for diarrhea due to hypofunction of the spleen, can be used as tonifying the lung spleen, control the adjuvant of the deficiency of vital energy; For cough due to fluid-retention, phlegm-damp enters network, aching pain in should and back etc., has again a function of invigorating spleen; Can be used for the diseases such as irritability, cardiopalmus, insomnia; Belong in insufficiency of the spleen leading to overabundance of dampness, phlegm retention in carcinoma such as the treatment esophageal carcinoma, gastric cancer, hepatocarcinoma, nasopharyngeal carcinoma, carcinoma of tongue, breast carcinoma, bladder cancer, pulmonary carcinoma, exedens melanoma etc. stop, damp and hot heap soil or fertilizer over and around the roots knot person.
Radix Et Rhizoma Rhei: cold is bitter.Return spleen, stomach, large intestine, liver, pericardium channel.Function: the stagnant constipation for the treatment of; Heat in blood tells nosebleed, conjunctival congestion pharyngalgia; Pathopyretic ulcer, burn and scald; The all cards of blood stasis; Hygropyretic dysentery, jaundice, stranguria.
Radix Glycyrrhizae: property is put down, and sweet in the mouth, returns 12 warps.There is removing toxic substances, eliminate the phlegm, pain relieving, spasmolytic is so that the pharmacological action such as anticancer.In the traditional Chinese medical science, Radix Glycyrrhizae invigorating the spleen and replenishing QI, grows and coughs lung moistening, and emergency is detoxified, and is in harmonious proportion hundred medicines.Cure mainly laryngopharynx swelling and pain, cellulitis skin infection, gastrointestinal ulceration and solution poison of drug, alimentary toxicosis etc.; Processed with honey cures mainly spleen and stomach function and goes down, and large loose stool is thin.
In the present invention, each medicine supplements and complements each other, and the mutual cooperation of various crude drug reaches medicine optimum curative effect.Root for flaming up of liver-fire is contained in liver-fire, damages edema with the liver involved, pathogenic fire derived from stagnation of liver-QI, pathogenic heat enemy intrusion or invasion, and in fire of moxibustion, life causes, and medicine of the present invention carries out concrete and medication targetedly, and the medicine for liver-fire Sheng, dampness has: Radix Gentianae, Fructus Gardeniae, Radix Scutellariae, the Radix Rehmanniae and Radix Et Rhizoma Rhei; Radix Bupleuri, Caulis Akebiae are used for evacuation and bring down a fever, soothing liver-QI, the function of yang invigorating, irritable feverish sensation in the chest, and Radix Angelicae Sinensis, Rhizoma Alismatis and Radix Glycyrrhizae also have spleen reinforcing lung, QI invigorating and calming the nerves, and Radix Bupleuri and Radix Angelicae Sinensis can improve effect of body immunity.To sum up, the present invention not only solves liver-fire and contains, damage edema with the liver involved, the flaming up of liver-fire that pathogenic fire derived from stagnation of liver-QI causes, and the effect also having soothing the liver, QI invigorating and calm the nerves, also improves effect of body immunity simultaneously.
Oral microsphere and its preparation technique of the present invention is simple, the micropill of preparation is fast in absorption of human body, the present invention is through overtesting, property of medicine analysis is carried out to material medicine, oral administration pills can play good drug effect, medicine increases at gastrointestinal tract surface distributed area, reduces or eliminates while drug bioavailability is increased to gastrointestinal zest; Both blood drug level can have been made after clothes to reach therapeutic effect rapidly, can maintain longer action time again, blood drug level is steady, and have repeatability, adverse reaction rate is low; Good looking appearance, good fluidity, dust is few.Micropill can be produced in enormous quantities through this method, removes the trouble that consumer does it yourself to make from, taking convenience.
The present invention in clinical case 200 example, total effective rate 100%, cure rate 95%.
The present invention treats the routine clinical observation result of morbid leukorrhea 200:
1. clinical data: age 20-50 year.
2. administrated method: oral liquid, the morning, noon and afternoon service once, each 1 bag, within 7 days, are a course for the treatment of.
3, therapeutic effect
(1) criterion of therapeutical effect
A. fully recover: symptom and sign disappears, do not recur after stopping using;
B. effective: symptom and sign disappears substantially.Comparatively the lighter is recurred after drug withdrawal.
C. invalid: to treat three months with clinical symptoms without improver.
(2) result: 190 examples of fully recovering (accounting for 95%), effective 10 examples (accounting for 5%), total effective rate 100%.
Detailed description of the invention
embodiment 1:
The medicine for the treatment of flaming up of liver-fire, this Chinese medicine composition is made up of the crude drug of following weight portion: Radix Gentianae 10-30 part, Fructus Gardeniae 1-30 part, Radix Scutellariae 5-30 part, Radix Bupleuri 10-30 part, Radix Angelicae Sinensis 5-20 part, Radix Rehmanniae 10-20 part, Caulis Akebiae 1-20 part, Rhizoma Alismatis 1-30 part, Radix Et Rhizoma Rhei 1-20 part, Radix Glycyrrhizae 1-20 part.
The weight portion of each crude drug of Chinese medicine composition is: Radix Gentianae 15 parts, Fructus Gardeniae 10 parts, Radix Scutellariae 10 parts, Radix Bupleuri 10 parts, Radix Angelicae Sinensis 10 parts, 12 parts, the Radix Rehmanniae, Caulis Akebiae 10 parts, Rhizoma Alismatis 6 parts, Radix Et Rhizoma Rhei 6 parts, 6 parts, Radix Glycyrrhizae.
The preparation method of the drug oral micropill for the treatment of flaming up of liver-fire, concrete steps are as follows:
A, crude drug process, by Radix Gentianae, Fructus Gardeniae, Radix Scutellariae, Radix Bupleuri, Radix Angelicae Sinensis, the Radix Rehmanniae, Caulis Akebiae, Rhizoma Alismatis, Radix Et Rhizoma Rhei, Radix Glycyrrhizae is cleaned, oven dry, reprocesses in flakes or section, is then milled into fine powder with pulverizer respectively, crosses 100-200 object sieve, obtains standby material;
B, mixing pill, add binding agent by the standby material in step a and obtain plasticity soft material, soft material is inserted molding machine and prepares micropill, micropill is inserted microwave dryer drying;
C, coating of pellets, the micropill coating solution obtained by step b carries out coating, and dry after coating, the oral dose per diem taking two or three times carries out evacuation pack.
Binding agent be syrup, sticky rice juice, 5 ~ 20% mucialga of arabic gummy or Resina persicae slurry.
Coating solution is Lac or cellulose acetate-phthalate.
embodiment 2:
The weight portion of each crude drug of the medicine for the treatment of flaming up of liver-fire is: Radix Gentianae 30 parts, Fructus Gardeniae 30 parts, Radix Scutellariae 30 parts, Radix Bupleuri 30 parts, Radix Angelicae Sinensis 20 parts, 10 parts, the Radix Rehmanniae, Caulis Akebiae 20 parts, Rhizoma Alismatis 1 part, Radix Et Rhizoma Rhei 1 part, 20 parts, Radix Glycyrrhizae.
The preparation method of the drug oral micropill for the treatment of flaming up of liver-fire, concrete steps are as follows:
A, crude drug process, by Radix Gentianae 30 parts, Fructus Gardeniae 30 parts, Radix Scutellariae 30 parts, Radix Bupleuri 30 parts, Radix Angelicae Sinensis 20 parts, 10 parts, the Radix Rehmanniae, Caulis Akebiae 20 parts, Rhizoma Alismatis 1 part, Radix Et Rhizoma Rhei 1 part, 20 parts, Radix Glycyrrhizae is cleaned, oven dry, reprocesses in flakes or section, is then milled into fine powder with pulverizer respectively, cross 100 object sieves, obtain standby material;
B, mixing pill, add binder syrup by the standby material in step a and obtain plasticity soft material, soft material is inserted molding machine and prepares micropill, micropill is inserted microwave dryer drying;
C, coating of pellets, the micropill coating solution Lac obtained by step b carries out coating, and dry after coating, the oral dose per diem taking three times carries out evacuation pack.
Case 1: Lee, female, 25 years old, Linzhou City of Henan Province appointed villages and small towns to appoint people from village, lassitude, feels dizzy distending pain, flushed face with red ears, the explosive irritability of emotion, menoxenia, through oligemia.Every natural gift morning, noon and afternoon take this micropill three times, fully recover after taking 3 courses for the treatment of.
Embodiment 3:
The weight portion of each crude drug of the medicine for the treatment of flaming up of liver-fire is: Radix Gentianae 10 parts, Fructus Gardeniae 1 part, Radix Scutellariae 5 parts, Radix Bupleuri 10 parts, Radix Angelicae Sinensis 5 parts, 20 parts, the Radix Rehmanniae, Caulis Akebiae 4 parts, Rhizoma Alismatis 30 parts, Radix Et Rhizoma Rhei 30 parts, 1 part, Radix Glycyrrhizae.
The preparation method of the drug oral micropill for the treatment of flaming up of liver-fire, concrete steps are as follows:
A, crude drug process, by Radix Gentianae 10 parts, Fructus Gardeniae 1 part, Radix Scutellariae 5 parts, Radix Bupleuri 10 parts, Radix Angelicae Sinensis 5 parts, 20 parts, the Radix Rehmanniae, Caulis Akebiae 4 parts, Rhizoma Alismatis 30 parts, Radix Et Rhizoma Rhei 30 parts, 1 part, Radix Glycyrrhizae is cleaned, oven dry, reprocesses in flakes or section, is then milled into fine powder with pulverizer respectively, crosses 200 object sieves, obtains standby material;
B, mixing pill, add binding agent sticky rice juice by the standby material in step a and obtain plasticity soft material, soft material is inserted molding machine and prepares micropill, micropill is inserted microwave dryer drying;
C, coating of pellets, the micropill coating solution cellulose acetate-phthalate obtained by step b carries out coating, carries out lyophilization after coating, and the oral dose per diem taking twice carries out evacuation pack.
Case 2: Wang, man, 36 years old, Linzhou City of Henan Province appointed villages and small towns to appoint people from village, and daytime, spirit was poor, easily dozed off, dizzy, and feeling of fatigue is obvious, gets up morning and there will be xerostomia, bitter taste.Take this micropill twice daily in morning and evening, fully recover after taking 4 courses for the treatment of.
Embodiment 4:
The weight portion of each crude drug of the medicine for the treatment of flaming up of liver-fire is: Radix Gentianae 20 parts, Fructus Gardeniae 20 parts, Radix Scutellariae 20 parts, Radix Bupleuri 20 parts, Radix Angelicae Sinensis 15 parts, 15 parts, the Radix Rehmanniae, Caulis Akebiae 15 parts, Rhizoma Alismatis 20 parts, Radix Et Rhizoma Rhei 10 parts, 10 parts, Radix Glycyrrhizae.
The preparation method of the drug oral micropill for the treatment of flaming up of liver-fire, concrete steps are as follows:
A, crude drug process, by Radix Gentianae 20 parts, Fructus Gardeniae 20 parts, Radix Scutellariae 20 parts, Radix Bupleuri 20 parts, Radix Angelicae Sinensis 15 parts, 15 parts, the Radix Rehmanniae, Caulis Akebiae 15 parts, Rhizoma Alismatis 20 parts, Radix Et Rhizoma Rhei 10 parts, 10 parts, Radix Glycyrrhizae is cleaned, oven dry, reprocesses in flakes or section, is then milled into fine powder with pulverizer respectively, cross 100 object sieves, obtain standby material;
B, mixing pill, the standby material in step a being added binding agent is that 5% mucialga of arabic gummy obtains plasticity soft material, soft material is inserted molding machine and prepares micropill, micropill is inserted microwave dryer drying;
C, coating of pellets, the micropill coating solution Lac obtained by step b carries out coating, carries out air-dry drying after coating, and the oral dose per diem taking three times carries out evacuation pack.
Case 3: Wang, man, 24 years old, Linzhou City of Henan Province appointed villages and small towns to appoint people from village, often feels dizzy distending pain, flushed face with red ears, the explosive irritability of emotion, and evening, sleep quality was not high, easily had a sleepless night.Every natural gift morning, noon and afternoon take this micropill three times, fully recover after taking 6 courses for the treatment of.
Embodiment 5
The weight portion of each crude drug of the medicine for the treatment of flaming up of liver-fire is: Radix Gentianae 25 parts, Fructus Gardeniae 15 parts, Radix Scutellariae 24 parts, Radix Bupleuri 18 parts, Radix Angelicae Sinensis 8 parts, 13 parts, the Radix Rehmanniae, Caulis Akebiae 15 parts, Rhizoma Alismatis 25 parts, Radix Et Rhizoma Rhei 15 parts, 15 parts, Radix Glycyrrhizae.
The preparation method of the drug oral micropill for the treatment of flaming up of liver-fire, concrete steps are as follows:
A, crude drug process, by Radix Gentianae 25 parts, Fructus Gardeniae 15 parts, Radix Scutellariae 24 parts, Radix Bupleuri 18 parts, Radix Angelicae Sinensis 8 parts, 13 parts, the Radix Rehmanniae, Caulis Akebiae 15 parts, Rhizoma Alismatis 25 parts, Radix Et Rhizoma Rhei 15 parts, 15 parts, Radix Glycyrrhizae is cleaned, oven dry, reprocesses in flakes or section, is then milled into fine powder with pulverizer respectively, cross 200 object sieves, obtain standby material;
B, mixing pill, the mucialga of arabic gummy standby material in step a being added binding agent 20% obtains plasticity soft material, soft material is inserted molding machine and prepares micropill, micropill is inserted microwave dryer drying;
C, coating of pellets, the micropill coating solution cellulose acetate-phthalate obtained by step b carries out coating, carries out lyophilization after coating, and the oral dose per diem taking three times carries out evacuation pack.
Case 4: Hu, female, 50 years old, Linzhou City of Henan Province appointed villages and small towns to appoint people from village, and evening, sleep quality was not high, easily insomnia, dreaminess, woke up with a start.Emotion is easily affected, and upsets, and loses control of temper, easy on the trigger.Every natural gift morning, noon and afternoon take this micropill three times, fully recover after taking 3 courses for the treatment of.
Embodiment 6
The weight portion of each crude drug of the medicine for the treatment of flaming up of liver-fire is: Radix Gentianae 10 parts, Fructus Gardeniae 5 parts, Radix Scutellariae 15 parts, Radix Bupleuri 20 parts, Radix Angelicae Sinensis 10 parts, 18 parts, the Radix Rehmanniae, Caulis Akebiae 15 parts, Rhizoma Alismatis 6 parts, Radix Et Rhizoma Rhei 6 parts, 15 parts, Radix Glycyrrhizae.
The preparation method of the drug oral micropill for the treatment of flaming up of liver-fire, concrete steps are as follows:
A, crude drug process, by Radix Gentianae 10 parts, Fructus Gardeniae 5 parts, Radix Scutellariae 15 parts, Radix Bupleuri 20 parts, Radix Angelicae Sinensis 10 parts, 18 parts, the Radix Rehmanniae, Caulis Akebiae 15 parts, Rhizoma Alismatis 6 parts, Radix Et Rhizoma Rhei 6 parts, 15 parts, Radix Glycyrrhizae is cleaned, oven dry, reprocesses in flakes or section, is then milled into fine powder with pulverizer respectively, crosses 100 object sieves, obtains standby material;
B, mixing pill, add binding agent Resina persicae and starch to obtain plasticity soft material, soft material is inserted molding machine and prepares micropill, micropill is inserted microwave dryer drying by the standby material in step a;
C, coating of pellets, the micropill coating solution cellulose acetate-phthalate obtained by step b carries out coating, carries out air-dry drying after coating, and the oral dose per diem taking three times carries out evacuation pack.
Case 5: go into business certain, female, 38 years old, Linzhou City of Henan Province appointed villages and small towns to appoint people from village, and feeling of fatigue is obvious; Evening, sleep quality was not high, easily insomnia, dreaminess, wake up with a start get up morning there will be xerostomia, bitter taste, tongue fur are sent out thick, gingival swelling and pain etc., delay menstrual period or amenorrhea.Every natural gift morning, noon and afternoon take this micropill three times, fully recover after taking 3 courses for the treatment of.
Claims (5)
1. treat the medicine of flaming up of liver-fire, it is characterized in that: this Chinese medicine composition is made up of the crude drug of following weight portion: Radix Gentianae 10-30 part, Fructus Gardeniae 1-30 part, Radix Scutellariae 5-30 part, Radix Bupleuri 10-30 part, Radix Angelicae Sinensis 5-20 part, Radix Rehmanniae 10-20 part, Caulis Akebiae 1-20 part, Rhizoma Alismatis 1-30 part, Radix Et Rhizoma Rhei 1-20 part, Radix Glycyrrhizae 1-20 part.
2. the medicine for the treatment of flaming up of liver-fire according to claim 1, it is characterized in that: the weight portion of each crude drug of described Chinese medicine composition is: Radix Gentianae 15 parts, Fructus Gardeniae 10 parts, Radix Scutellariae 10 parts, Radix Bupleuri 10 parts, Radix Angelicae Sinensis 10 parts, 12 parts, the Radix Rehmanniae, Caulis Akebiae 10 parts, Rhizoma Alismatis 6 parts, Radix Et Rhizoma Rhei 6 parts, 6 parts, Radix Glycyrrhizae.
3. the preparation method of the drug oral micropill for the treatment of flaming up of liver-fire according to claim 1 and 2, is characterized in that: concrete steps are as follows:
A, crude drug process, by Radix Gentianae, Fructus Gardeniae, Radix Scutellariae, Radix Bupleuri, Radix Angelicae Sinensis, the Radix Rehmanniae, Caulis Akebiae, Rhizoma Alismatis, Radix Et Rhizoma Rhei, Radix Glycyrrhizae is cleaned, oven dry, reprocesses in flakes or section, is then milled into fine powder with pulverizer respectively, crosses 100-200 object sieve, obtains standby material;
B, mixing pill, add binding agent by the standby material in step a and obtain plasticity soft material, soft material is inserted molding machine and prepares micropill, micropill is inserted microwave dryer drying;
C, coating of pellets, the micropill coating solution obtained by step b carries out coating, and dry after coating, the oral dose per diem taking two or three times carries out evacuation pack.
4. the preparation method of the drug oral micropill for the treatment of flaming up of liver-fire according to claim 3, is characterized in that: described binding agent be syrup, sticky rice juice, 5 ~ 20% mucialga of arabic gummy or Resina persicae slurry.
5. the preparation method of the drug oral micropill for the treatment of flaming up of liver-fire according to claim 3, is characterized in that: described coating solution is Lac or cellulose acetate-phthalate.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105582199A (en) * | 2016-02-04 | 2016-05-18 | 王树青 | Pharmaceutical composition for treating animal babesiasis |
| CN106390042A (en) * | 2016-12-13 | 2017-02-15 | 四川西奈生物科技有限公司 | Traditional Chinese medicine composition for hepatic calculus discharging |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105582199A (en) * | 2016-02-04 | 2016-05-18 | 王树青 | Pharmaceutical composition for treating animal babesiasis |
| CN106390042A (en) * | 2016-12-13 | 2017-02-15 | 四川西奈生物科技有限公司 | Traditional Chinese medicine composition for hepatic calculus discharging |
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Application publication date: 20150520 |