CN104606569A - Yin-nourishing and eyesight-improving preparation for treating radiation cataract and preparation method - Google Patents
Yin-nourishing and eyesight-improving preparation for treating radiation cataract and preparation method Download PDFInfo
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Abstract
The invention discloses a Yin-nourishing and eyesight-improving preparation for treating radiation cataract and a preparation method. The preparation is prepared from the following medicinal raw materials in parts by weight: 18-26 parts of bighead atractylodes rhizome, 9-17 parts of coffee senna, 12-20 parts of wolfberry fruits, 8-15 parts of sheargrass, 9-16 parts of folium eriobotryae, 7-15 parts of amaranth, 13-20 parts of angelica sinensis, 11-18 parts of rust-brown crotalaria, 12-18 parts of botrychium japonicum, 18-26 parts of polygala tenuifolia, 6-15 parts of gorgon fruits, 8-16 parts of medicated leaven, 10-15 parts of viola, 13-18 parts of polygonum multiflorum, 14-18 parts of herb of manybranch meadowrue, 5-13 parts of bitter bamboo leaves and 8-16 parts of spiraea roots. The preparation disclosed by the invention is exact in curative effect, difficult to relapse, free of risk, low in treatment expense and free of toxic or side effects, and treats both symptoms and root causes.
Description
Technical field
The present invention relates to traditional Chinese medicine field, YIN nourishing improving eyesight preparation particularly relating to a kind of radiotherapy cataract and preparation method thereof.
Background technology
Radiational cataract is the common clinically a kind of disease of occupation disease, in the professional radiation disease that China has diagnosed, be in second.Because of the lenticular opacity caused by lonizing radiation, be called radiational cataract, also someone is classified to traumatic cataract.Mainly contain with Types Below: the cataract 1, caused by infrared ray.The multiple workman being born in glass factory and steel mill, because of fusing high temp glass and steel plant produce short infrared absorbed after, produce lenticular opacity.First after date cortex has cavity, point-like and thread-like opacity, similar spider reticulation, has golden yellow crystalline gloss.Develop into plate-like muddiness gradually later.Finally develop into total cataract.Sometimes also little cloudy is had under anterior capsule.2, the cataract of caused by ionizing radiation.The ray of ionizing radiation comprises neutron, x-ray, γ line and high-octane β line, can cause cataract after irradiating crystal.Incubation period differs in length, and has direct relation with radiological dose size and age.Dosage is large, age little person is short for incubation period.Have cavity and canescence granular cloud under initial stage posterior lens capsule film, little point-like muddiness develops into ring-type muddiness gradually, and anterior capsule hypopallium has point-like, wire and featheriness muddy, extremely outwards radiates in the past.Can there be plate-like and wedge shape muddiness in later stage, finally forms total cataract.3, cataract caused by microwave.Microwave derives from solar rays, cosmic ray and TV, radar, microwave oven etc.Heavy dose of microwave can produce and be similar to ultrared heat effect.Crystalline lens, to microwave susceptible, because the dosage difference of microwave can produce the different infringement of crystalline lens, is similar to the cataract caused by infrared ray.Crystalline lens is muddy and frontal cortex pinniform muddiness under there is cortex point-like muddiness, Lens capsular.
Application publication number CN103768244A(application number 201210412093.X) Chinese patent literature disclose one and treat cataractous medicine, it is made up of the raw material of following weight proportioning: Radix Angelicae Sinensis 10 ~ 30, Radix Bupleuri 6 ~ 15, Fructus Leonuri 10 ~ 20, Fructus Lycii 10 ~ 25, Semen Plantaginis 10 ~ 25, Concha Haliotidis 15 ~ 35, Semen Cassiae 15 ~ 25, Spica Prunellae 15 ~ 35, Radix Glycyrrhizae 3 ~ 10.Application publication number CN102973775A(application number 201210554072.1) Chinese patent literature disclose one and treat cataractous medicine, be made up of the raw material of following parts by weight: Semen Cuscutae 10-20 part, Flos Chrysanthemi 5-10 part, Sanguis Draxonis 5-10 part, Radix Puerariae 10-20 part, Radix Scutellariae 15-20 part, Flos Eriocauli 13-15 part, Fel Bovis seu Bubali 5-20 part, Herba Menthae 4-15 part, Semen phaseoli radiati 13-18 part, Fructus Lycii 14-23 part, Radix Schisandrae Bicoloris 8-15 part, Radix Angelicae Sinensis 6-19 part, Radix Aconiti Lateralis Preparata 8-20 part, Cornu Cervi Pantotrichum 15-20 part, Colla Corii Asini 10-20 part, longan 5-10 part, Rhizoma Acori Graminei 2-8 part, Radix Polygalae 3-9 part, Rhizoma Anemarrhenae 4-7 part, Semen Plantaginis 5-10 part, Rhizoma Dioscoreae 2-5 part, Os Sepiae 15-20 part.Application publication number CN104208315A(application number 201410412487.4) Chinese patent literature disclose one and be used for the treatment of cataractous eye drop, make eye drop by Flos Inulae, Thallus Laminariae (Thallus Eckloniae), Fructus Lycii, Flos Chrysanthemi, Fructus Schisandrae Chinensis, Fructus Ligustri Lucidi, Rhizoma Acori Graminei, Semen Plantaginis, Radix Angelicae Sinensis.
Up to now specific medicament be there is no to the treatment of radiational cataract.The at present collyrium such as main catalin, card woods excellent, phacolin, glutathion, catalin, BDL, treatment is not suitable for the patient performed the operation in early days or temporarily, but its definite curative effect waits summary research.And adopt cataractopiesis to treat, the postoperative crystalline lens of implantable artificial within the eye or wear glasses or corneal contact lens to correct defects of vision, operative treatment risk is high, and medical expense is high.
Summary of the invention
For the deficiencies in the prior art, YIN nourishing improving eyesight preparation that the object of this invention is to provide a kind of radiotherapy cataract and preparation method thereof.Determined curative effect of the present invention, treating both the principal and secondary aspects of a disease, more after not easily recurrence, devoid of risk, medical expense low, have no side effect.
Technical scheme of the present invention is:
The YIN nourishing improving eyesight preparation of radiotherapy cataract, takes off the primary raw material medicine stating weight proportion and is prepared from: Rhizoma Atractylodis Macrocephalae 18-26, Herba cassiae occidentalis 9-17, Fructus Lycii 12-20, Herba clinopodii confinis (Herba Clinopodii Gracilis) 8-15, Folium Eriobotryae 9-16, Herba Amaranthi tricoloris 7-15, Radix Angelicae Sinensis 13-20, Herba Crotalariae Ferrugineae 11-18, Botrychium japonicum (Prantl) underw 12-18, Radix Polygalae 18-26, Semen Euryales 6-15, Massa Medicata Fermentata 8-16, Herba Violae 10-15, Radix Polygoni Multiflori 13-18, Herba Thalictri Ramosi 14-18, Folium Pleioblasti 5-13, Radix spiraeae japonicae 8-16.
The YIN nourishing improving eyesight preparation of radiotherapy cataract, preferred scheme is, takes off the primary raw material medicine stating weight proportion and is prepared from: Rhizoma Atractylodis Macrocephalae 20-24, Herba cassiae occidentalis 11-13, Fructus Lycii 14-17, Herba clinopodii confinis (Herba Clinopodii Gracilis) 9-13, Folium Eriobotryae 12-15, Herba Amaranthi tricoloris 9-13, Radix Angelicae Sinensis 15-18, Herba Crotalariae Ferrugineae 13-16, Botrychium japonicum (Prantl) underw 13-16, Radix Polygalae 21-24, Semen Euryales 9-12, Massa Medicata Fermentata 10-14, Herba Violae 11-13, Radix Polygoni Multiflori 14-16, Herba Thalictri Ramosi 15-17, Folium Pleioblasti 7-10, Radix spiraeae japonicae 10-13.
The YIN nourishing improving eyesight preparation of radiotherapy cataract, the scheme be more preferably is, takes off the primary raw material medicine stating weight proportion and is prepared from: the Rhizoma Atractylodis Macrocephalae 22, Herba cassiae occidentalis 12, Fructus Lycii 15, Herba clinopodii confinis (Herba Clinopodii Gracilis) 11, Folium Eriobotryae 14, Herba Amaranthi tricoloris 12, Radix Angelicae Sinensis 16, Herba Crotalariae Ferrugineae 14, Botrychium japonicum (Prantl) underw 15, Radix Polygalae 22, Semen Euryales 10, Massa Medicata Fermentata 12, Herba Violae 12, Radix Polygoni Multiflori 15, Herba Thalictri Ramosi 16, Folium Pleioblasti 8, Radix spiraeae japonicae 11.
Present invention also offers the preparation method YIN nourishing improving eyesight preparation of aforementioned therapies radiational cataract being made pharmaceutically acceptable powder, pill, granule, Tablet and Capsula agent.
The preparation method of described powder is:
(1) Pulvis Talci is put in pot, talcous weight is the weight of the 1/4-1/2(preferably talc powder of Semen Euryales weight is 1/3 of Semen Euryales weight), heating is with high heat stirred, when frying to sliding sharp state, drop into Semen Euryales, constantly stir, fry to foresythia, take out, well sifted Pulvis Talci, cool, be ground into fine powder, cross No. seven sieves;
(2) add water in pot, amount of water be the 10-15 of Folium Pleioblasti weight doubly (preferred amount of water is 12 times of Folium Pleioblasti weight), put into Folium Pleioblasti after being heated to boil, maintain micro-6-12 of boiling minute (preferably maintaining micro-boiling 10 minutes), from fire, remove slag extracting juice;
(3) all the other the 15 taste crude drug except Semen Euryales and Folium Pleioblasti are ground into fine powder respectively, cross No. seven sieves;
(4) step (1) and step (3) gained fine powder are fully mixed;
(5) step (2) gained medicine juice is condensed into the paste medicine (preferably step (2) gained medicine juice being condensed into the paste medicine that relative density is 1.34) that relative density is 1.31-1.36, add 95% ethanol and gained paste medicine grinds altogether, add the fine powder after step (4) mixing again, grind well, drying 24 hours in the vacuum drying oven of 50 DEG C, be distributed into and often wrap 5g, sterile packaged, to obtain final product.
The preparation method of described pill is:
(1) Pulvis Talci is put in pot, talcous weight is the weight of the 1/4-1/2(preferably talc powder of Semen Euryales weight is 1/3 of Semen Euryales weight), heating is with high heat stirred, when frying to sliding sharp state, drop into Semen Euryales, constantly stir, fry to foresythia, take out, well sifted Pulvis Talci, cool, be ground into fine powder, cross No. six sieves;
(2) add water in pot, amount of water be the 10-15 of Folium Pleioblasti weight doubly (preferred amount of water is 12 times of Folium Pleioblasti weight), put into Folium Pleioblasti after being heated to boil, maintain micro-6-12 of boiling minute (preferably maintaining micro-boiling 10 minutes), from fire, remove slag extracting juice;
(3) all the other the 15 taste crude drug except Semen Euryales and Folium Pleioblasti are ground into fine powder respectively, cross No. six sieves;
(4) step (1) and step (3) gained fine powder are fully mixed, with the general ball of step (2) gained medicine juice, make the pill of the heavy 0.15g of every ball.
The preparation method of described granule is:
(1) Pulvis Talci is put in pot, talcous weight is the weight of the 1/4-1/2(preferably talc powder of Semen Euryales weight is 1/3 of Semen Euryales weight), heating is with high heat stirred, when frying to sliding sharp state, drop into Semen Euryales, constantly stir, fry to foresythia, take out, well sifted Pulvis Talci, cool, be ground into fine powder, cross No. six sieves;
(2) add water in pot, amount of water be the 10-15 of Folium Pleioblasti weight doubly (preferred amount of water is 12 times of Folium Pleioblasti weight), put into Folium Pleioblasti after being heated to boil, maintain micro-6-12 of boiling minute (preferably maintaining micro-boiling 10 minutes), from fire, remove slag extracting juice;
(3) all the other the 15 taste crude drug except Semen Euryales and Folium Pleioblasti are ground into fine powder respectively, cross No. six sieves;
(4) by step (1) and step (3) gained fine powder mix homogeneously, fine powder after mix homogeneously and mass fraction be 14% starch slurry make altogether, make soft material, 14 mesh sieves are granulated, wet granular spreads out in enamel tray, to put in baking oven 60 DEG C and is dried to pellet moisture and controls about 4%, be more evenly sprayed at by step (2) gained medicine juice in dry granule, sealing placement 60 minutes, packs and get final product.
The preparation method of described tablet is:
(1) Pulvis Talci is put in pot, talcous weight is the weight of the 1/4-1/2(preferably talc powder of Semen Euryales weight is 1/3 of Semen Euryales weight), heating is with high heat stirred, when frying to sliding sharp state, drop into Semen Euryales, constantly stir, fry to foresythia, take out, well sifted Pulvis Talci, cool, be ground into fine powder, cross No. six sieves;
(2) add water in pot, amount of water be the 10-15 of Folium Pleioblasti weight doubly (preferred amount of water is 12 times of Folium Pleioblasti weight), put into Folium Pleioblasti after being heated to boil, maintain micro-6-12 of boiling minute (preferably maintaining micro-boiling 10 minutes), from fire, remove slag extracting juice;
(3) all the other the 15 taste crude drug except Semen Euryales and Folium Pleioblasti are ground into fine powder respectively, cross No. six sieves;
(4) by step (1) and step (3) gained fine powder mix homogeneously, fine powder after mix homogeneously and mass fraction be 14% starch slurry make altogether, make soft material, 14 mesh sieves are granulated, and wet granular spreads out in enamel tray, to put in baking oven 60 DEG C and are dried to pellet moisture and control about 4%, again step (2) gained medicine juice is evenly sprayed in dry granule, tabletting, the heavy 0.25g of every sheet, to obtain final product.
The preparation method of described capsule is:
(1) Pulvis Talci is put in pot, talcous weight is the weight of the 1/4-1/2(preferably talc powder of Semen Euryales weight is 1/3 of Semen Euryales weight), heating is with high heat stirred, when frying to sliding sharp state, drop into Semen Euryales, constantly stir, fry to foresythia, take out, well sifted Pulvis Talci, cool, be ground into fine powder, cross No. six sieves;
(2) add water in pot, amount of water be the 10-15 of Folium Pleioblasti weight doubly (preferred amount of water is 12 times of Folium Pleioblasti weight), put into Folium Pleioblasti after being heated to boil, maintain micro-6-12 of boiling minute (preferably maintaining micro-boiling 10 minutes), from fire, remove slag extracting juice;
(3) step (2) gained medicine juice is condensed into the thick paste (preferably step (2) gained medicine juice being condensed into the thick paste that relative density is 1.32) that relative density is 1.30-1.34, dry at the temperature of 50 DEG C-70 DEG C (preferably dry at the temperature of 65 DEG C), dry 10-24 hour (preferably dry 18 hours), be ground into fine powder, cross No. six sieves;
(4) all the other the 15 taste crude drug except Semen Euryales and Folium Pleioblasti are ground into fine powder respectively, cross No. six sieves;
(5) by step (1), step (3) and step (4) gained fine powder mix homogeneously, drying 15 hours at the temperature of 60 DEG C, spread out in stainless steel disc, thickness is 15-25mm, microwave sterilizating 4-7 minute (preferred microwave sterilizating 6 minutes), loads zero capsule, every capsules is equipped with medicated powder 0.35g, by the capsule polishing in buffing machine installed, pressing plate, to obtain final product.
The YIN nourishing improving eyesight preparation taking convenience of radiotherapy cataract provided by the invention, to be easy to carry.In addition, excellent results of the present invention also shows:
1, determined curative effect;
2, devoid of risk, medical expense low, have no side effect, mental pressure and the economic pressures of patient can be alleviated, patient
Be easy to accept;
3, preparation method is simple;
4, there is the effects such as YIN nourishing improving eyesight, invigorating the spleen and benefiting QI, nourishing the kidney and liver, promoting flow of QI and blood, radiational cataract can be made to reach thorough healing, and treating both the principal and secondary aspects of a disease, not easily recur more.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
embodiment 1the YIN nourishing improving eyesight preparation of radiotherapy cataract, the primary raw material medicine getting following weight parts is prepared from (every part is 150g): the Rhizoma Atractylodis Macrocephalae 18 parts, Herba cassiae occidentalis 9 parts, Fructus Lycii 12 parts, Herba clinopodii confinis (Herba Clinopodii Gracilis) 8 parts, Folium Eriobotryae 9 parts, Herba Amaranthi tricoloris 7 parts, Radix Angelicae Sinensis 13 parts, Herba Crotalariae Ferrugineae 11 parts, Botrychium japonicum (Prantl) underw 12 parts, Radix Polygalae 18 parts, Semen Euryales 6 parts, Massa Medicata Fermentata 8 parts, Herba Violae 10 parts, Radix Polygoni Multiflori 13 parts, Herba Thalictri Ramosi 14 parts, Folium Pleioblasti 5 parts, Radix spiraeae japonicae 8 parts.
The preparation method of the YIN nourishing improving eyesight preparation pill of above-mentioned radiotherapy cataract is:
(1) put in pot by Pulvis Talci, talcous weight is 1/3 of Semen Euryales weight, and heating is with high heat stirred, and when frying to sliding sharp state, drop into Semen Euryales, constantly stir, fry to foresythia, take out, well sifted Pulvis Talci, cools, and is ground into fine powder, crosses No. six sieves;
(2) add water in pot, amount of water is 12 times of Folium Pleioblasti weight, and put into Folium Pleioblasti after being heated to boil, remain micro-and boil 10 minutes, from fire, remove slag extracting juice;
(3) all the other the 15 taste crude drug except Semen Euryales and Folium Pleioblasti are ground into fine powder respectively, cross No. six sieves;
(4) step (1) and step (3) gained fine powder are fully mixed, with the general ball of step (2) gained medicine juice, make the pill of the heavy 0.15g of every ball.
The using method of the YIN nourishing improving eyesight preparation pill of gained radiotherapy cataract of the present invention is: oral, and every day three times, each 3-5 ball, warm water takes.
embodiment 2the YIN nourishing improving eyesight preparation of radiotherapy cataract, the primary raw material medicine getting following weight parts is prepared from (every part is 150g): the Rhizoma Atractylodis Macrocephalae 26 parts, Herba cassiae occidentalis 17 parts, Fructus Lycii 20 parts, Herba clinopodii confinis (Herba Clinopodii Gracilis) 15 parts, Folium Eriobotryae 16 parts, Herba Amaranthi tricoloris 15 parts, Radix Angelicae Sinensis 20 parts, Herba Crotalariae Ferrugineae 18 parts, Botrychium japonicum (Prantl) underw 18 parts, Radix Polygalae 26 parts, Semen Euryales 15 parts, Massa Medicata Fermentata 16 parts, Herba Violae 15 parts, Radix Polygoni Multiflori 18 parts, Herba Thalictri Ramosi 18 parts, Folium Pleioblasti 13 parts, Radix spiraeae japonicae 16 parts.
The preparation method of the YIN nourishing improving eyesight preparation granules agent of above-mentioned radiotherapy cataract is:
(1) put in pot by Pulvis Talci, talcous weight is 1/3 of Semen Euryales weight, and heating is with high heat stirred, and when frying to sliding sharp state, drop into Semen Euryales, constantly stir, fry to foresythia, take out, well sifted Pulvis Talci, cools, and is ground into fine powder, crosses No. six sieves;
(2) add water in pot, amount of water is 12 times of Folium Pleioblasti weight, and put into Folium Pleioblasti after being heated to boil, remain micro-and boil 10 minutes, from fire, remove slag extracting juice;
(3) all the other the 15 taste crude drug except Semen Euryales and Folium Pleioblasti are ground into fine powder respectively, cross No. six sieves;
(4) by step (1) and step (3) gained fine powder mix homogeneously, fine powder after mix homogeneously and mass fraction be 14% starch slurry make altogether, make soft material, 14 mesh sieves are granulated, wet granular spreads out in enamel tray, to put in baking oven 60 DEG C and is dried to pellet moisture and controls about 4%, be more evenly sprayed at by step (2) gained medicine juice in dry granule, sealing placement 60 minutes, packs and get final product.
model case one:open XX, man, 49 years old.Main suit: headache, eyesight weaken, hypomnesis 6 years.Patient is radiology department technologist-in-charge, and previously body is good for, without other harmful and noxious substance contact histories, without trauma history, without special family history.Before 6 years when radiology department's staff's health examination, conscious headache, eyesight weaken, hypomnesis.Be diagnosed as radiational cataract.Once accepted Drug therapy, weak effect, and came to go to a doctor.Ultrasound diagnosis is shown: crystalline lens average thickness is 4.2mm, and crystalline lens is complete fusiformis structure.Right vision 0.7, left vision 0.5.Be diagnosed as radiational cataract.Take the YIN nourishing improving eyesight preparation granules agent of the present embodiment gained radiotherapy cataract, every day three times, each 12g, boiled water is taken after mixing it with water.Take 2 months, above-mentioned symptom takes a turn for the better to some extent.Continue to take 1 first quarter moon, above-mentioned symptom all disappears, and vision restoration is normal.Follow up a case by regular visits to and do not recur so far.
embodiment 3the YIN nourishing improving eyesight preparation of radiotherapy cataract, the primary raw material medicine getting following weight parts is prepared from (every part is 150g): the Rhizoma Atractylodis Macrocephalae 20 parts, Herba cassiae occidentalis 11 parts, Fructus Lycii 14 parts, Herba clinopodii confinis (Herba Clinopodii Gracilis) 9 parts, Folium Eriobotryae 12 parts, Herba Amaranthi tricoloris 9 parts, Radix Angelicae Sinensis 15 parts, Herba Crotalariae Ferrugineae 13 parts, Botrychium japonicum (Prantl) underw 13 parts, Radix Polygalae 21 parts, Semen Euryales 9 parts, Massa Medicata Fermentata 10 parts, Herba Violae 11 parts, Radix Polygoni Multiflori 14 parts, Herba Thalictri Ramosi 15 parts, Folium Pleioblasti 7 parts, Radix spiraeae japonicae 10 parts.
The preparation method of the YIN nourishing improving eyesight formulation tablet of above-mentioned radiotherapy cataract is:
(1) put in pot by Pulvis Talci, talcous weight is 1/3 of Semen Euryales weight, and heating is with high heat stirred, and when frying to sliding sharp state, drop into Semen Euryales, constantly stir, fry to foresythia, take out, well sifted Pulvis Talci, cools, and is ground into fine powder, crosses No. six sieves;
(2) add water in pot, amount of water is 12 times of Folium Pleioblasti weight, and put into Folium Pleioblasti after being heated to boil, remain micro-and boil 10 minutes, from fire, remove slag extracting juice;
(3) all the other the 15 taste crude drug except Semen Euryales and Folium Pleioblasti are ground into fine powder respectively, cross No. six sieves;
(4) by step (1) and step (3) gained fine powder mix homogeneously, fine powder after mix homogeneously and mass fraction be 14% starch slurry make altogether, make soft material, 14 mesh sieves are granulated, and wet granular spreads out in enamel tray, to put in baking oven 60 DEG C and are dried to pellet moisture and control about 4%, again step (2) gained medicine juice is evenly sprayed in dry granule, tabletting, the heavy 0.25g of every sheet, to obtain final product.
model case two: yellow XX, female, 47 years old.Main suit: visual deterioration, blurring of vision, dizzy 5 years.Patient is X-ray technician, conscious visual deterioration before 5 years, blurring of vision, dizzy.Once Drug therapy was accepted, without taking a turn for the better.Ultrasound diagnosis is shown: crystalline lens average thickness is 5mm, crystalline lens structure spherical in shape, and under the forward and backward capsule of bicrystal, lamellar is muddy, and crystal transparency declines.Right vision 0.6, left vision 0.5.Be diagnosed as radiational cataract.Take the YIN nourishing improving eyesight formulation tablet of the present embodiment gained radiotherapy cataract, every day three times, each 2, warm water takes.Take 1 month, above-mentioned symptom alleviates.Continue to take two months, all disease knowing disappear, and vision restoration is normal.Follow-up observation is not recurred.
embodiment 4the YIN nourishing improving eyesight preparation of radiotherapy cataract, the primary raw material medicine getting following weight parts is prepared from (every part is 150g): the Rhizoma Atractylodis Macrocephalae 24 parts, Herba cassiae occidentalis 13 parts, Fructus Lycii 17 parts, Herba clinopodii confinis (Herba Clinopodii Gracilis) 13 parts, Folium Eriobotryae 15 parts, Herba Amaranthi tricoloris 13 parts, Radix Angelicae Sinensis 18 parts, Herba Crotalariae Ferrugineae 16 parts, Botrychium japonicum (Prantl) underw 16 parts, Radix Polygalae 24 parts, Semen Euryales 12 parts, Massa Medicata Fermentata 14 parts, Herba Violae 13 parts, Radix Polygoni Multiflori 16 parts, Herba Thalictri Ramosi 17 parts, Folium Pleioblasti 10 parts, Radix spiraeae japonicae 13 parts.
The preparation method of the YIN nourishing improving eyesight preparation capsule of above-mentioned radiotherapy cataract is:
(1) put in pot by Pulvis Talci, talcous weight is 1/3 of Semen Euryales weight, and heating is with high heat stirred, and when frying to sliding sharp state, drop into Semen Euryales, constantly stir, fry to foresythia, take out, well sifted Pulvis Talci, cools, and is ground into fine powder, crosses No. six sieves;
(2) add water in pot, amount of water is 12 times of Folium Pleioblasti weight, and put into Folium Pleioblasti after being heated to boil, remain micro-and boil 10 minutes, from fire, remove slag extracting juice;
(3) step (2) gained medicine juice is condensed into the thick paste that relative density is 1.32, dry at the temperature of 65 DEG C, dry 18 hours, be ground into fine powder, cross No. six sieves;
(4) all the other the 15 taste crude drug except Semen Euryales and Folium Pleioblasti are ground into fine powder respectively, cross No. six sieves;
(5) by step (1), step (3) and step (4) gained fine powder mix homogeneously, drying 15 hours at the temperature of 60 DEG C, spread out in stainless steel disc, thickness is 15-25mm, microwave sterilizating 6 minutes, loads zero capsule, every capsules is equipped with medicated powder 0.35g, by the capsule polishing in buffing machine installed, pressing plate, to obtain final product.
model case three:liu XX, man, 60 years old.Main suit: blurred vision, visual deterioration 10 years.Patient was once engaged in radiation work 15 years, because there is fatigue and weak, headache, hypomnesis, the symptoms such as subcutaneous hemorrhage, being diagnosed as ray reaction, hospitalization, after this departing from ray work 15 years.Check and to find after bicrystal under capsule that lamellar is muddy and see cavity, under front capsule, point-like is muddy.Be diagnosed as radiational cataract.Take the YIN nourishing improving eyesight preparation capsule of the present embodiment gained radiotherapy cataract, every day three times, each 2, warm water takes.Take two months, patient is conscious, and blurred vision symptom takes a turn for the better to some extent.Continue to take 1 first quarter moon, vision is recovered completely.Recurrence of following up a case by regular visits to that so far there are no.
embodiment 5the YIN nourishing improving eyesight preparation of radiotherapy cataract, the primary raw material medicine getting following weight parts is prepared from (every part is 150g): the Rhizoma Atractylodis Macrocephalae 22 parts, Herba cassiae occidentalis 12 parts, Fructus Lycii 15 parts, Herba clinopodii confinis (Herba Clinopodii Gracilis) 11 parts, Folium Eriobotryae 14 parts, Herba Amaranthi tricoloris 12 parts, Radix Angelicae Sinensis 16 parts, Herba Crotalariae Ferrugineae 14 parts, Botrychium japonicum (Prantl) underw 15 parts, Radix Polygalae 22 parts, Semen Euryales 10 parts, Massa Medicata Fermentata 12 parts, Herba Violae 12 parts, Radix Polygoni Multiflori 15 parts, Herba Thalictri Ramosi 16 parts, Folium Pleioblasti 8 parts, Radix spiraeae japonicae 11 parts.
The preparation method of the YIN nourishing improving eyesight preparation powder of above-mentioned radiotherapy cataract is:
(1) put in pot by Pulvis Talci, talcous weight is 1/3 of Semen Euryales weight, and heating is with high heat stirred, and when frying to sliding sharp state, drop into Semen Euryales, constantly stir, fry to foresythia, take out, well sifted Pulvis Talci, cools, and is ground into fine powder, crosses No. seven sieves;
(2) add water in pot, amount of water is 12 times of Folium Pleioblasti weight, and put into Folium Pleioblasti after being heated to boil, remain micro-and boil 10 minutes, from fire, remove slag extracting juice;
(3) all the other the 15 taste crude drug except Semen Euryales and Folium Pleioblasti are ground into fine powder respectively, cross No. seven sieves;
(4) step (1) and step (3) gained fine powder are fully mixed;
(5) step (2) gained medicine juice is condensed into the paste medicine that relative density is 1.34, adds 95% ethanol and gained paste medicine grinds altogether, then add the fine powder after step (4) mixing, grind well, in the vacuum drying oven of 50 DEG C, drying 24 hours, is distributed into and often wraps 5g, sterile packaged, to obtain final product.
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
The Rhizoma Atractylodis Macrocephalae: base is former: be the dry rhizome of the feverfew Rhizoma Atractylodis Macrocephalae.The property of medicine: bitter, sweet, temperature.Return spleen, stomach warp.Function cures mainly: invigorating the spleen and benefiting QI, dampness diuretic, and hidroschesis is antiabortive.For insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.Rhizoma Atractylodis Macrocephalae spleen invigorating, stomach function regulating, antiabortive.For insufficiency of the spleen lack of appetite, loose stool of having loose bowels, frequent fetal movement.
Herba cassiae occidentalis: base is former: be the stem and leaf of leguminous plant Herba cassiae occidentalis.The property of medicine: bitter; Cold.Return lung, liver, stomach warp.Function cures mainly: respectful lung, liver heat removing, diuresis, relieving constipation, removing toxic substances and promoting subsidence of swelling.Main cough and asthma, headache conjunctival congestion, urine stranguria with blood, constipation, carbuncle sore tumefacting virus, snake bite and insect sting.
Fructus Lycii: base is former: be the mature fruit of matrimony vine of solanaceae plant or lycium barbarum.The property of medicine: sweet, flat.Return liver, kidney channel.Function cures mainly: nourishing kidney, lung moistening, tonifying liver, improving eyesight.Control hepatic and renal YIN deficiency, soreness of the waist and knees, dizzy, dizzy, the many tear of blurred vision, cough due to consumptive disease, quenches one's thirst, seminal emission.
Herba clinopodii confinis (Herba Clinopodii Gracilis): base is former: the herb of finishing the meeting for labiate C. gracile and contiguous wind wheel.The property of medicine: bitter in the mouth; Pungent; Cool in nature.Function cures mainly: expelling wind and clearing away heat, promoting flow of QI and blood, removing toxic substances and promoting subsidence of swelling.Main cold, fever, abdominal pain due to retention of food, vomiting, has loose bowels, dysentery, diphtheria, laryngopharynx swelling and pain, carbuncle erysipelas, urticaria, insect-bite, and traumatic injury wound is hemorrhage.
Folium Eriobotryae: base is former: be the leaf of rosaceous plant Folium Eriobotryae.The property of medicine: bitter, pungent; Cold; Nontoxic.Return lung, the heart, stomach warp.Function cures mainly: clearing away lung-heat to relieve cough, and regulating the stomach and sending down the abnormal ascending QI is quenched the thirst.Main lung-heat phlegmatic cough, deficiency of YIN chronic cough, hemoptysis, epistaxis, gastric heat is vomitted the sound of vomiting.
Herba Amaranthi tricoloris: another name: Amaranthus mangostanus L., people Herba Amaranthi tricoloris, rising star Herba Amaranthi tricoloris, Herba amaranthi tricoloris, old and young year, ten sample brocades, an old person having a young heart' a person old in age but young in spirit, tampala, QINGXIANG Herba Amaranthi tricoloris, always become, Qiu Hong, be the stem and leaf of amaranthaceous plant Herba Amaranthi tricoloris.The property of medicine: sweet; Cold nature.Return large intestine, small intestine meridian.Function cures mainly: heat-clearing and toxic substances removing, smoothening secretion.Main dysentery, constipation and anuresis, snakeworm sting, sore.
Radix Angelicae Sinensis: base is former: be the dry root of umbelliferae angelica.The property of medicine: sweet, acrid, warm.Return liver, the heart, spleen channel.Function cures mainly: enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.For blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, traumatic injury, ulcer sores.Radix Angelicae Sinensis (processed with wine) promoting blood circulation to restore menstrual flow.For amenorrhea dysmenorrhea, rheumatic arthralgia, traumatic injury.
Herba Crotalariae Ferrugineae: base is former: the herb blue for the false ground of leguminous plant or whole herb with root.The property of medicine: bitter micro-acid, flat, cold.Return lung meridian.Function cures mainly: nourishing the kidney and liver, relieving cough and asthma, eliminating damp, detoxifying.Cure mainly tinnitus, deaf, the vertigo, seminal emission, menorrhagia, leucorrhea, chronic cough expectorant blood, asthma, nephritis, dysuria, tonsillitis, parotitis, furuncle swelling toxin.
Botrychium japonicum (Prantl) underw: base is former: be herb or the rhizome of Botrychiaceae plant Botrychium japonicum (Prantl) underw.The property of medicine: sweet; Bitter; Be slightly cold.Return liver, lung meridian.Function cures mainly: liver heat removing and eyesight improving, detumescence of reducing phlegm.Main conjunctival congestion and swelling pain, infantile hyperpyrexia is twitched, cough, spits blood, scrofula, carbuncle skin ulcer.
Radix Polygalae: base is former: be the dry root of milk wort Radix Polygalae or ovum leaf Radix Polygalae.The property of medicine: bitter, pungent, temperature.GUIXIN, kidney, lung meridian.Function cures mainly: Fructus Alpiniae Oxyphyllae of calming the nerves, and eliminates the phlegm, detumescence.For the insomnia and dreamful sleep that disarmony between the heart and kidney causes, forgetful palpitation with fear, staring spells, expectoration is not well, sore swollen toxin, breast swell and pain.
Semen Euryales: base is former: be the mature seed kernel of nymphaeaceae plant Gorgon euryale.Chemical analysis: seed is containing volume starch.Containing 4.4 grams, protein in every 100 grams, 0.2 gram, fat, carbohydrate 32 grams, crude fibre 0.4 gram, ash 0.5 gram, calcium 9 milligrams, 110 milligrams, phosphorus, ferrum 0.4 milligram, thiamine 0.40 milligram, 0.08 milligram, riboflavin, nicotinic acid 2.5 milligrams, 6 milligrams, ascorbic acid, carotene trace.The property of medicine: sweet, puckery, flat.Return spleen, kidney channel.Function cures mainly: reinforcing the kindey to control nocturnal emission, spleen reinforcing stopping leak.Control seminal emission, stranguria with turbid discharge, leukorrhagia, incontinence of urine, loose stool and diarrhea.
Massa Medicata Fermentata: base is former: for the medicines such as Herba polygoni hydropiperis, Herba Artemisiae Annuae, Semen Armeniacae Amarum add flour or wheat bran mixed after, through the herbal leaven of fermentation.Chemical analysis: Massa Medicata Fermentata is yeast preparation, containing yeast, amylase, vitamin B complex, ergosterol, protein and fat, volatilization wet goods.The property of medicine: sweet; Pungent; Temperature; Nontoxic.Return spleen, stomach warp.Function cures mainly: invigorating the spleen and regulating the stomach, promoting digestion and removing stagnation.Main retention of food and drink, dyspepsia, distension and fullness in the abdomen, inappetence, vomiting dysentery.
Herba Violae: base is former: be Violaceae Chinese violet, Herba Violae japonicae; The whole herb with root of leguminous plant Gueldenstaedtia verna, little Gueldenstaedtia verna or gentianaceae plant Gentiana.The property of medicine: bitter, cold. be included into the heart, Liver Channel.Function cures mainly: clearing away heat-damp and promoting diuresis, removing toxic substances and promoting subsidence of swelling.Control furuncle, carbuncle, scrofula, jaundice, dysentery, diarrhoea, conjunctival congestion, sore throat, venom.
Radix Polygoni Multiflori: base is former: be the dried root of polygonum multiflorum thunb.The property of medicine: bitter, sweet, puckery, temperature.Return liver, heart kidney channel.Function cures mainly: removing toxic substances, disappears de-, loosening bowel to relieve constipation.For scrofula carbuncle sore, rubella pruritus, dryness of the intestine constipation, hyperlipidemia.
Herba Thalictri Ramosi: base is former: be the herb of ranunculaceae plant racemosus Thalictrum aquilegifolium L. var. sibiricum Regel.The property of medicine: bitter in the mouth; Cold in nature.Return liver, large intestine channel.Function cures mainly: heat clearing and damp drying; Removing toxic substances.Cure mainly dysentery, jaundice, conjunctival congestion, carbuncle furuncle.
Folium Pleioblasti: base is former: be the tender leaf of grass bitter bamboo.The property of medicine: bitter; Cold.GUIXIN, Liver Channel.Function cures mainly: clear away heart-fire, diuresis improving eyesight, removing toxic substances.Main calentura excessive thirst, insomnia, oliguria with reddish urine, aphtha, ophthalmalgia, aphonia, burn and scald.
Radix spiraeae japonicae: base is former: be the root of rosaceous plant pink blossom Ramulus et Folium Spiraeae Salicifolia, light leaf Ramulus et Folium Spiraeae Salicifolia.The property of medicine: bitter, pungent; Cool; Nontoxic.Return lung, Liver Channel.Function cures mainly: expelling wind and clearing away heat, improving acuity of vision and removing nebula.Main cough, headache, toothache, cataract.
test example 1the clinical practice of the YIN nourishing improving eyesight preparation (embodiment 5) of gained radiotherapy cataract of the present invention: in March, 2006 in December ,-2011, screen 300 routine radiational cataract patients in 6 hospitals.Be divided into two groups at random, experimental group and matched group.Experimental group male 82 example, women 68 example, oldest 70 years old, minimum 38 years old of age, 55.2 years old mean age, course of disease 1-13, average course of disease 4.3 years.Matched group male 83 example, women 67 example, oldest 71 years old, minimum 40 years old of age, 56 years old mean age, course of disease 1-13, average course of disease 4.5 years.The physical data no significant difference such as two groups of case sexes, age, courses of disease, have comparability (P > 0.05).
Diagnostic criteria
The occupational history of ionizing radiation, dosage and cataractous Morphological Features is accepted according to person under inspection, by GBZ95-2002 " radiational cataract diagnostic criteria ", after getting rid of other cataract caused by Non-ionizing radiation factor such as traumatic, congenital, senile, make diagnosis.
Therapeutic Method
Experimental group uses the YIN nourishing improving eyesight preparation of gained radiotherapy cataract of the present invention, using method: every day twice, each 5g, and boiled water is taken after mixing it with water, and within 15 days, is a course for the treatment of.Matched group uses the medicine (as phacolin, catalin, catalin etc.) of conventional therapy radiational cataract, within 15 days, is a course for the treatment of.After two groups of patients all treat four courses for the treatment of, carry out Comparison of therapeutic.
The criterion of curative effect situation
Cure: clinical symptoms and sign disappear, patient's binocular vision recovers normal, without sense of discomfort, does not recur more; Take a turn for the better: clinical symptoms and sign take a turn for the better, and binocular vision increases, but does not recover completely; Invalid: disease is unchanged.Total effectively comprising cures and takes a turn for the better.After treating four courses for the treatment of, result is as shown in table 1.
Table 1: the YIN nourishing improving eyesight preparation compliance test result of gained radiotherapy cataract of the present invention
Efficacy analysis: after two groups of cases treat four courses for the treatment of, experimental group cures 95 examples, and take a turn for the better 51 examples, invalid 4 examples, total effective rate 97.33%; Matched group cures 51 examples, and take a turn for the better 60 examples, invalid 39 examples, total effective rate 74%.The cure rate of experimental group and total effective rate are apparently higher than matched group.The clinical efficacy of experimental group is obviously better than matched group, and significant difference (P < 0.05), has statistical significance.
The present invention, through scientific compatibility, selects the Chinese medicines such as the Rhizoma Atractylodis Macrocephalae, Herba cassiae occidentalis, Fructus Lycii and Herba clinopodii confinis (Herba Clinopodii Gracilis) to be primary raw material, makes the YIN nourishing improving eyesight preparation of radiotherapy cataract.Rhizoma Atractylodis Macrocephalae invigorating the spleen and benefiting QI in side, dampness diuretic, hidroschesis, antiabortive.The respectful lung of Herba cassiae occidentalis, liver heat removing, diuresis, relieving constipation, removing toxic substances and promoting subsidence of swelling.Fructus Lycii nourishing kidney, lung moistening, tonifying liver, improving eyesight.Herba clinopodii confinis (Herba Clinopodii Gracilis) expelling wind and clearing away heat, promoting flow of QI and blood, removing toxic substances and promoting subsidence of swelling.Folium Eriobotryae clearing away lung-heat to relieve cough, regulating the stomach and sending down the abnormal ascending QI, quenches the thirst.Herba Amaranthi tricoloris heat-clearing and toxic substances removing, smoothening secretion.Chinese angelica blood supplementing is invigorated blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.Herba Crotalariae Ferrugineae nourishing the kidney and liver, relieving cough and asthma, eliminating damp, detoxifying.Botrychium japonicum (Prantl) underw liver heat removing and eyesight improving, detumescence of reducing phlegm.Radix Polygalae is calmed the nerves Fructus Alpiniae Oxyphyllae, eliminates the phlegm, detumescence.Semen Euryales reinforcing the kindey to control nocturnal emission, spleen reinforcing stopping leak.Massa Medicata Fermentata invigorating the spleen and regulating the stomach, promoting digestion and removing stagnation.Herba Violae clearing away heat-damp and promoting diuresis, removing toxic substances and promoting subsidence of swelling.Radix Polygoni Multiflori detoxifies, and disappears de-, loosening bowel to relieve constipation.Herba Thalictri Ramosi heat clearing and damp drying, removing toxic substances.Folium Pleioblasti clears away heart-fire, diuresis improving eyesight, removing toxic substances.Radix spiraeae japonicae expelling wind and clearing away heat, improving acuity of vision and removing nebula.All medicines share, and have the effects such as YIN nourishing improving eyesight, invigorating the spleen and benefiting QI, nourishing the kidney and liver, promoting flow of QI and blood, radiational cataract can be made to reach thorough healing, and treating both the principal and secondary aspects of a disease, not easily recur more.
Finally it should be noted that, embodiment is the detailed description of the invention of optimum of the present invention, be not limited to the present invention, although with reference to previous embodiment to invention has been detailed description, for a person skilled in the art, it still can be modified to the technical scheme described in foregoing embodiments, or carries out equivalent replacement to wherein portion of techniques feature.Within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.
Claims (10)
1. the YIN nourishing improving eyesight preparation of radiotherapy cataract, is characterized in that, takes off the primary raw material medicine stating weight proportion and is prepared from: Rhizoma Atractylodis Macrocephalae 18-26, Herba cassiae occidentalis 9-17, Fructus Lycii 12-20, Herba clinopodii confinis (Herba Clinopodii Gracilis) 8-15, Folium Eriobotryae 9-16, Herba Amaranthi tricoloris 7-15, Radix Angelicae Sinensis 13-20, Herba Crotalariae Ferrugineae 11-18, Botrychium japonicum (Prantl) underw 12-18, Radix Polygalae 18-26, Semen Euryales 6-15, Massa Medicata Fermentata 8-16, Herba Violae 10-15, Radix Polygoni Multiflori 13-18, Herba Thalictri Ramosi 14-18, Folium Pleioblasti 5-13, Radix spiraeae japonicae 8-16.
2. the YIN nourishing improving eyesight preparation of radiotherapy cataract as claimed in claim 1, is characterized in that, take off the primary raw material medicine stating weight proportion and be prepared from: Rhizoma Atractylodis Macrocephalae 20-24, Herba cassiae occidentalis 11-13, Fructus Lycii 14-17, Herba clinopodii confinis (Herba Clinopodii Gracilis) 9-13, Folium Eriobotryae 12-15, Herba Amaranthi tricoloris 9-13, Radix Angelicae Sinensis 15-18, Herba Crotalariae Ferrugineae 13-16, Botrychium japonicum (Prantl) underw 13-16, Radix Polygalae 21-24, Semen Euryales 9-12, Massa Medicata Fermentata 10-14, Herba Violae 11-13, Radix Polygoni Multiflori 14-16, Herba Thalictri Ramosi 15-17, Folium Pleioblasti 7-10, Radix spiraeae japonicae 10-13.
3. the YIN nourishing improving eyesight preparation of radiotherapy cataract as claimed in claim 1, is characterized in that, take off the primary raw material medicine stating weight proportion and be prepared from: the Rhizoma Atractylodis Macrocephalae 22, Herba cassiae occidentalis 12, Fructus Lycii 15, Herba clinopodii confinis (Herba Clinopodii Gracilis) 11, Folium Eriobotryae 14, Herba Amaranthi tricoloris 12, Radix Angelicae Sinensis 16, Herba Crotalariae Ferrugineae 14, Botrychium japonicum (Prantl) underw 15, Radix Polygalae 22, Semen Euryales 10, Massa Medicata Fermentata 12, Herba Violae 12, Radix Polygoni Multiflori 15, Herba Thalictri Ramosi 16, Folium Pleioblasti 8, Radix spiraeae japonicae 11.
4. the YIN nourishing improving eyesight preparation of the radiotherapy cataract as described in as arbitrary in claims 1 to 3, it is characterized in that, the YIN nourishing improving eyesight preparation of this radiotherapy cataract is made pharmaceutically acceptable powder, and the preparation method of described powder is:
(1) Pulvis Talci is put in pot, talcous weight is the weight of the 1/4-1/2(preferably talc powder of Semen Euryales weight is 1/3 of Semen Euryales weight), heating is with high heat stirred, when frying to sliding sharp state, drop into Semen Euryales, constantly stir, fry to foresythia, take out, well sifted Pulvis Talci, cool, be ground into fine powder, cross No. seven sieves;
(2) add water in pot, amount of water be the 10-15 of Folium Pleioblasti weight doubly (preferred amount of water is 12 times of Folium Pleioblasti weight), put into Folium Pleioblasti after being heated to boil, maintain micro-6-12 of boiling minute (preferably maintaining micro-boiling 10 minutes), from fire, remove slag extracting juice;
(3) all the other the 15 taste crude drug except Semen Euryales and Folium Pleioblasti are ground into fine powder respectively, cross No. seven sieves;
(4) step (1) and step (3) gained fine powder are fully mixed;
(5) step (2) gained medicine juice is condensed into the paste medicine (preferably step (2) gained medicine juice being condensed into the paste medicine that relative density is 1.34) that relative density is 1.31-1.36, add 95% ethanol and gained paste medicine grinds altogether, add the fine powder after step (4) mixing again, grind well, drying 24 hours in the vacuum drying oven of 50 DEG C, be distributed into and often wrap 5g, sterile packaged, to obtain final product.
5. the YIN nourishing improving eyesight preparation of the radiotherapy cataract as described in as arbitrary in claims 1 to 3, it is characterized in that, the YIN nourishing improving eyesight preparation of this radiotherapy cataract is made pharmaceutically acceptable pill, and the preparation method of described pill is:
(1) Pulvis Talci is put in pot, talcous weight is the weight of the 1/4-1/2(preferably talc powder of Semen Euryales weight is 1/3 of Semen Euryales weight), heating is with high heat stirred, when frying to sliding sharp state, drop into Semen Euryales, constantly stir, fry to foresythia, take out, well sifted Pulvis Talci, cool, be ground into fine powder, cross No. six sieves;
(2) add water in pot, amount of water be the 10-15 of Folium Pleioblasti weight doubly (preferred amount of water is 12 times of Folium Pleioblasti weight), put into Folium Pleioblasti after being heated to boil, maintain micro-6-12 of boiling minute (preferably maintaining micro-boiling 10 minutes), from fire, remove slag extracting juice;
(3) all the other the 15 taste crude drug except Semen Euryales and Folium Pleioblasti are ground into fine powder respectively, cross No. six sieves;
(4) step (1) and step (3) gained fine powder are fully mixed, with the general ball of step (2) gained medicine juice, make the pill of the heavy 0.15g of every ball.
6. the YIN nourishing improving eyesight preparation of the radiotherapy cataract as described in as arbitrary in claims 1 to 3, it is characterized in that, the YIN nourishing improving eyesight preparation of this radiotherapy cataract is made pharmaceutically acceptable granule, and the preparation method of described granule is:
(1) Pulvis Talci is put in pot, talcous weight is the weight of the 1/4-1/2(preferably talc powder of Semen Euryales weight is 1/3 of Semen Euryales weight), heating is with high heat stirred, when frying to sliding sharp state, drop into Semen Euryales, constantly stir, fry to foresythia, take out, well sifted Pulvis Talci, cool, be ground into fine powder, cross No. six sieves;
(2) add water in pot, amount of water be the 10-15 of Folium Pleioblasti weight doubly (preferred amount of water is 12 times of Folium Pleioblasti weight), put into Folium Pleioblasti after being heated to boil, maintain micro-6-12 of boiling minute (preferably maintaining micro-boiling 10 minutes), from fire, remove slag extracting juice;
(3) all the other the 15 taste crude drug except Semen Euryales and Folium Pleioblasti are ground into fine powder respectively, cross No. six sieves;
(4) by step (1) and step (3) gained fine powder mix homogeneously, fine powder after mix homogeneously and mass fraction be 14% starch slurry make altogether, make soft material, 14 mesh sieves are granulated, wet granular spreads out in enamel tray, to put in baking oven 60 DEG C and is dried to pellet moisture and controls about 4%, be more evenly sprayed at by step (2) gained medicine juice in dry granule, sealing placement 60 minutes, packs and get final product.
7. the YIN nourishing improving eyesight preparation of the radiotherapy cataract as described in as arbitrary in claims 1 to 3, it is characterized in that, the YIN nourishing improving eyesight preparation of this radiotherapy cataract is made pharmaceutically acceptable tablet, and the preparation method of described tablet is:
(1) Pulvis Talci is put in pot, talcous weight is the weight of the 1/4-1/2(preferably talc powder of Semen Euryales weight is 1/3 of Semen Euryales weight), heating is with high heat stirred, when frying to sliding sharp state, drop into Semen Euryales, constantly stir, fry to foresythia, take out, well sifted Pulvis Talci, cool, be ground into fine powder, cross No. six sieves;
(2) add water in pot, amount of water be the 10-15 of Folium Pleioblasti weight doubly (preferred amount of water is 12 times of Folium Pleioblasti weight), put into Folium Pleioblasti after being heated to boil, maintain micro-6-12 of boiling minute (preferably maintaining micro-boiling 10 minutes), from fire, remove slag extracting juice;
(3) all the other the 15 taste crude drug except Semen Euryales and Folium Pleioblasti are ground into fine powder respectively, cross No. six sieves;
(4) by step (1) and step (3) gained fine powder mix homogeneously, fine powder after mix homogeneously and mass fraction be 14% starch slurry make altogether, make soft material, 14 mesh sieves are granulated, and wet granular spreads out in enamel tray, to put in baking oven 60 DEG C and are dried to pellet moisture and control about 4%, again step (2) gained medicine juice is evenly sprayed in dry granule, tabletting, the heavy 0.25g of every sheet, to obtain final product.
8. the YIN nourishing improving eyesight preparation of the radiotherapy cataract as described in as arbitrary in claims 1 to 3, it is characterized in that, the YIN nourishing improving eyesight preparation of this radiotherapy cataract is made pharmaceutically acceptable capsule, and the preparation method of described capsule is:
(1) Pulvis Talci is put in pot, talcous weight is the weight of the 1/4-1/2(preferably talc powder of Semen Euryales weight is 1/3 of Semen Euryales weight), heating is with high heat stirred, when frying to sliding sharp state, drop into Semen Euryales, constantly stir, fry to foresythia, take out, well sifted Pulvis Talci, cool, be ground into fine powder, cross No. six sieves;
(2) add water in pot, amount of water be the 10-15 of Folium Pleioblasti weight doubly (preferred amount of water is 12 times of Folium Pleioblasti weight), put into Folium Pleioblasti after being heated to boil, maintain micro-6-12 minute that boils, from fire, remove slag extracting juice;
(3) step (2) gained medicine juice is condensed into the thick paste (preferably step (2) gained medicine juice being condensed into the thick paste that relative density is 1.32) that relative density is 1.30-1.34, dry at the temperature of 50 DEG C-70 DEG C (preferably dry at the temperature of 65 DEG C), dry 10-24 hour (preferably dry 18 hours), be ground into fine powder, cross No. six sieves;
(4) all the other the 15 taste crude drug except Semen Euryales and Folium Pleioblasti are ground into fine powder respectively, cross No. six sieves;
(5) by step (1), step (3) and step (4) gained fine powder mix homogeneously, drying 15 hours at the temperature of 60 DEG C, spread out in stainless steel disc, thickness is 15-25mm, microwave sterilizating 4-7 minute, loads zero capsule, every capsules is equipped with medicated powder 0.35g, by the capsule polishing in buffing machine installed, pressing plate, to obtain final product.
9. the preparation method of the YIN nourishing improving eyesight preparation capsule of radiotherapy cataract as claimed in claim 8, is characterized in that, maintains micro-boiling 10 minutes in step (2).
10. the preparation method of the YIN nourishing improving eyesight preparation capsule of radiotherapy cataract as claimed in claim 8, is characterized in that, microwave sterilizating 6 minutes in step (5).
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| CN107617045A (en) * | 2017-10-30 | 2018-01-23 | 杨小丽 | A kind of medicine for treating kidney deficiency eye mist and preparation method thereof |
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| CN1899304A (en) * | 2006-07-07 | 2007-01-24 | 中国科学院南海海洋研究所 | Eye drops for cataract and its preparing method |
| CN103341020A (en) * | 2013-07-29 | 2013-10-09 | 阚景平 | Traditional Chinese medicine preparation for treating radiation cataract and preparation method thereof |
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| CN1899304A (en) * | 2006-07-07 | 2007-01-24 | 中国科学院南海海洋研究所 | Eye drops for cataract and its preparing method |
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Address after: 550000 Nanming City, Guiyang Province, Qingshan District, No. 6, building 1, unit 502, 53, Applicant after: Li Jun Address before: Lixia District, Shandong city of Ji'nan Province, 250000 mountain East Road No. 23 Applicant before: Li Jun |
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Application publication date: 20150513 |