CN104541167A - 用于定量肿瘤组织中的免疫细胞的方法及其应用 - Google Patents
用于定量肿瘤组织中的免疫细胞的方法及其应用 Download PDFInfo
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- CN104541167A CN104541167A CN201380030888.7A CN201380030888A CN104541167A CN 104541167 A CN104541167 A CN 104541167A CN 201380030888 A CN201380030888 A CN 201380030888A CN 104541167 A CN104541167 A CN 104541167A
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- G01N33/57492—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds localized on the membrane of tumor or cancer cells
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
- G01N33/5047—Cells of the immune system
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- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
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Abstract
Description
标准的组合 | A组 | B组 | C组 |
C1 | 7 | 4 | 3 |
C2 | 7 | 5 | 3 |
C3 | 10 | 4 | 3 |
C4 | 10 | 5 | 3 |
C5 | 6 | 4 | 3 |
C6 | 6 | 5 | 3 |
C7 | 9 | 4 | 3 |
C8 | 9 | 5 | 3 |
C9 | 4 | 4 | 3 |
C10 | 4 | 5 | 3 |
C11 | 3 | 4 | 3 |
C12 | 3 | 5 | 3 |
C13 | 5 | 4 | 3 |
C14 | 5 | 5 | 3 |
C15 | 7 | 4 | 2 |
Claims (12)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
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IBPCT/IB2012/001446 | 2012-06-14 | ||
IB2012001446 | 2012-06-14 | ||
PCT/EP2013/062405 WO2013186374A1 (en) | 2012-06-14 | 2013-06-14 | Method for quantifying immune cells in tumoral tissues and its applications |
Publications (2)
Publication Number | Publication Date |
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CN104541167A true CN104541167A (zh) | 2015-04-22 |
CN104541167B CN104541167B (zh) | 2018-05-01 |
Family
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CN201380030888.7A Active CN104541167B (zh) | 2012-06-14 | 2013-06-14 | 用于定量肿瘤组织中的免疫细胞的方法及其应用 |
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Country | Link |
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US (1) | US10317408B2 (zh) |
EP (1) | EP2861986B1 (zh) |
JP (1) | JP6449765B2 (zh) |
KR (1) | KR102179848B1 (zh) |
CN (1) | CN104541167B (zh) |
AU (1) | AU2013276470B2 (zh) |
BR (1) | BR112014031143B8 (zh) |
CA (1) | CA2873278C (zh) |
DE (1) | DE13731071T1 (zh) |
ES (1) | ES2902879T3 (zh) |
IL (1) | IL235738B (zh) |
SG (1) | SG11201408107RA (zh) |
WO (1) | WO2013186374A1 (zh) |
Cited By (10)
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CN106846310A (zh) * | 2017-01-19 | 2017-06-13 | 宁波江丰生物信息技术有限公司 | 一种基于免疫组化技术的病理辅助分析方法 |
CN109196554A (zh) * | 2016-05-18 | 2019-01-11 | 豪夫迈·罗氏有限公司 | 肿瘤接近度量 |
CN109690314A (zh) * | 2016-05-09 | 2019-04-26 | 法国国家卫生及研究医学协会 | 患有实体癌症的患者的分类方法 |
CN110168561A (zh) * | 2016-10-27 | 2019-08-23 | 皇家飞利浦有限公司 | 用于确定一个或多个组织样本中的细胞组成信息的装置 |
CN111551546A (zh) * | 2020-06-01 | 2020-08-18 | 南京瑟斯检测科技有限公司 | 一种基于光学微腔结构超材料的免疫组化便捷检测方法 |
CN113454458A (zh) * | 2019-02-05 | 2021-09-28 | 文塔纳医疗***公司 | 用于评估iv期结直肠癌中免疫细胞浸润的方法和*** |
CN113515077A (zh) * | 2021-04-23 | 2021-10-19 | 重庆德方信息技术有限公司 | 人体细胞染色过程监控***及方法 |
CN113671186A (zh) * | 2015-10-23 | 2021-11-19 | 诺华股份有限公司 | 对包含肿瘤组织的样品评分的方法 |
CN116646088A (zh) * | 2023-07-27 | 2023-08-25 | 广东省人民医院 | 一种预测方法、装置、设备及介质 |
TWI838687B (zh) * | 2021-01-30 | 2024-04-11 | 奇美醫療財團法人奇美醫院 | 評估腫瘤標本免疫狀態的方法 |
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---|---|---|---|---|
EP3111221B2 (en) | 2014-02-24 | 2022-01-19 | Ventana Medical Systems, Inc. | Methods, kits, and systems for scoring the immune response to cancer by simultaneous detection of cd3, cd8, cd20 and foxp3. |
CA2955156C (en) * | 2014-09-03 | 2024-04-30 | Ventana Medical Systems, Inc. | Systems and methods for generating fields of view |
WO2016073760A1 (en) | 2014-11-05 | 2016-05-12 | The Regents Of The University Of California | Methods for stratifying non-responders to therapies that block pd1/pdl1 axis |
US10632151B2 (en) | 2015-01-22 | 2020-04-28 | University Of Massachusetts | Cancer immunotherapy |
EP3532638A4 (en) | 2016-10-31 | 2020-07-29 | University of Massachusetts | TARGETING MICROARN-101-3 P IN CARCINOTHERAPY |
WO2019020556A1 (en) * | 2017-07-24 | 2019-01-31 | Ventana Medical Systems, Inc. | METHODS AND SYSTEMS FOR ASSESSING INFILTRAT OF IMMUNE CELLS IN TUMOR SAMPLES |
US11814623B2 (en) | 2018-01-30 | 2023-11-14 | University Of Massachusetts | Methods of treating a wound using epigenetic regulation |
WO2020245155A1 (en) | 2019-06-03 | 2020-12-10 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods for modulating a treatment regimen |
WO2021092071A1 (en) | 2019-11-07 | 2021-05-14 | Oncxerna Therapeutics, Inc. | Classification of tumor microenvironments |
JP2023531290A (ja) | 2020-06-30 | 2023-07-21 | アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル | 術前補助療法及び根治手術後の固形がんを患っている患者の再発及び/又は死亡のリスクを予測するための方法 |
WO2022002873A1 (en) | 2020-06-30 | 2022-01-06 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods for predicting the risk of recurrence and/or death of patients suffering from a solid cancer after preoperative adjuvant therapies |
CN113092202A (zh) * | 2021-03-25 | 2021-07-09 | 上海福君基因生物科技有限公司 | 一种胃癌预后预测装置 |
WO2023018085A1 (ko) * | 2021-08-10 | 2023-02-16 | 주식회사 루닛 | 병리 슬라이드 이미지와 관련된 정보를 출력하는 방법 및 장치 |
WO2023175366A1 (en) | 2022-03-17 | 2023-09-21 | Veracyte | Methods for predicting response to an immunotherapeutic treatment in a patient with a cancer |
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2013
- 2013-06-14 SG SG11201408107RA patent/SG11201408107RA/en unknown
- 2013-06-14 KR KR1020157000987A patent/KR102179848B1/ko active IP Right Grant
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- 2013-06-14 DE DE13731071.0T patent/DE13731071T1/de active Pending
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- 2013-06-14 ES ES13731071T patent/ES2902879T3/es active Active
- 2013-06-14 US US14/407,698 patent/US10317408B2/en active Active
- 2013-06-14 BR BR112014031143A patent/BR112014031143B8/pt active IP Right Grant
- 2013-06-14 AU AU2013276470A patent/AU2013276470B2/en active Active
- 2013-06-14 JP JP2015516637A patent/JP6449765B2/ja active Active
- 2013-06-14 CN CN201380030888.7A patent/CN104541167B/zh active Active
- 2013-06-14 EP EP13731071.0A patent/EP2861986B1/en active Active
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- 2014-11-17 IL IL235738A patent/IL235738B/en active IP Right Grant
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Cited By (13)
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CN113671186A (zh) * | 2015-10-23 | 2021-11-19 | 诺华股份有限公司 | 对包含肿瘤组织的样品评分的方法 |
CN109690314A (zh) * | 2016-05-09 | 2019-04-26 | 法国国家卫生及研究医学协会 | 患有实体癌症的患者的分类方法 |
CN109690314B (zh) * | 2016-05-09 | 2022-08-02 | 法国国家卫生及研究医学协会 | 患有实体癌症的患者的分类方法 |
CN109196554B (zh) * | 2016-05-18 | 2024-02-02 | 豪夫迈·罗氏有限公司 | 肿瘤接近度量 |
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CN110168561A (zh) * | 2016-10-27 | 2019-08-23 | 皇家飞利浦有限公司 | 用于确定一个或多个组织样本中的细胞组成信息的装置 |
CN106846310A (zh) * | 2017-01-19 | 2017-06-13 | 宁波江丰生物信息技术有限公司 | 一种基于免疫组化技术的病理辅助分析方法 |
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TWI838687B (zh) * | 2021-01-30 | 2024-04-11 | 奇美醫療財團法人奇美醫院 | 評估腫瘤標本免疫狀態的方法 |
CN113515077A (zh) * | 2021-04-23 | 2021-10-19 | 重庆德方信息技术有限公司 | 人体细胞染色过程监控***及方法 |
CN116646088B (zh) * | 2023-07-27 | 2023-12-01 | 广东省人民医院 | 一种预测方法、装置、设备及介质 |
CN116646088A (zh) * | 2023-07-27 | 2023-08-25 | 广东省人民医院 | 一种预测方法、装置、设备及介质 |
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CN104541167B (zh) | 2018-05-01 |
DE13731071T1 (de) | 2016-08-18 |
EP2861986B1 (en) | 2021-11-10 |
WO2013186374A1 (en) | 2013-12-19 |
EP2861986A1 (en) | 2015-04-22 |
JP2015525349A (ja) | 2015-09-03 |
BR112014031143B8 (pt) | 2022-11-22 |
KR20150023760A (ko) | 2015-03-05 |
KR102179848B1 (ko) | 2020-11-17 |
IL235738A0 (en) | 2015-01-29 |
IL235738B (en) | 2019-02-28 |
JP6449765B2 (ja) | 2019-01-09 |
US10317408B2 (en) | 2019-06-11 |
AU2013276470B2 (en) | 2018-06-07 |
CA2873278C (en) | 2021-10-26 |
AU2013276470A1 (en) | 2014-11-27 |
BR112014031143B1 (pt) | 2022-03-03 |
CA2873278A1 (en) | 2013-12-19 |
SG11201408107RA (en) | 2015-01-29 |
US20150153349A1 (en) | 2015-06-04 |
BR112014031143A2 (pt) | 2017-08-08 |
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