CN104509552A - Disinfectant fluid for cleaning oxygen mask for cardiovascular internal medicine and preparation method thereof - Google Patents

Disinfectant fluid for cleaning oxygen mask for cardiovascular internal medicine and preparation method thereof Download PDF

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CN104509552A
CN104509552A CN201410478508.2A CN201410478508A CN104509552A CN 104509552 A CN104509552 A CN 104509552A CN 201410478508 A CN201410478508 A CN 201410478508A CN 104509552 A CN104509552 A CN 104509552A
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parts
disinfectant
hour
oxygen mask
internal medicine
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聂文红
张兆贵
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Abstract

The invention discloses a disinfectant fluid for cleaning an oxygen mask for cardiovascular internal medicine; the disinfectant fluid comprises the following components by weight: 1-3 parts of peroxyacetic acid, 1-5 parts of hydrogen peroxide, 3-6 parts of metronidazole, 4-9 parts of phenol, 6-10 parts of bohadschia graeffei, 2-6 parts of sodium hypochlorite, and 1-5 parts of a herba centellae extract. The developed disinfectant fluid for ward internal disinfection is colorless and transparent in appearance and stable in physical and chemical indicator performance, generates no crystallization, turbidity and precipitates during use, and has physical and chemical indicators showed stably. Compared with the prior art, the prepared disinfectant has the advantages of low production cost, simple preparation process, easy realization of process conditions, and good product stability; and a volatile oil extracted from traditional Chinese medicines is added, the smell is aromatic, and patients feel blissfully happy.

Description

A kind of disinfectant for cleaning Internal Medicine-Cardiovascular Dept. oxygen mask and method for making
Technical field
The present invention relates to a kind of disinfectant, being specifically related to a kind of disinfectant for cleaning Internal Medicine-Cardiovascular Dept. oxygen mask and method for making.
Background technology
Cardiological, i.e. Internal Medicine-Cardiovascular Dept., be the clinical department that the large internal medicine of situation of all-level hospitals is arranged in order to the cardiovascular vascular disease of diagnosis and treatment, the disease for the treatment of comprises the angiocardiopathies such as angina pectoris, hypertension, sudden death, arrhythmia cordis, heart failure, premature beat, cardiac arrhythmia, myocardial infarction, cardiomyopathy, myocarditis, miocardial infarction.Common disease: coronary heart disease, hypertension, arrhythmia cordis, atrial fibrillation, PSVT, heart failure, myocarditis, congenital heart disease, cardiomyopathy, atrial septal defect, rheumatic heart disease, myocardial infarction, angina pectoris, acute infective endocarditis, myocardial ischemia.Some serious cardiological patients are needed to use oxygen mask.
Oxygen mask provides the method that can be transferred to the oxygen of besoin de respirer human lung from storage tank.Mainly contain the kinds such as the oxygen mask of medical oxygen face shield, aviation oxygen mask and airline passengers use, disease therapy, protection passenger and pilot are played an important role safely.Primarily of plastics, organosilicon, or rubber is made.Oxygen mask provides the method that can be transferred to the oxygen of besoin de respirer human lung from storage tank.Oxygen mask may wrap up nose and face (oral cavity nose cup) or whole face (full facepiece mask).Guarantee health, protection pilot and airline passengers are played an important role safely.
At present, a kind of disinfectant for cleaning Internal Medicine-Cardiovascular Dept. oxygen mask specially is seldom had in existing patent, publication number 101720760A (application number 200810157978.3) patent discloses a kind of haemodialysis control unit multifunctional disinfecting water, its with Peracetic acid and hydrogen peroxide for primary raw material, add stabilizing agent Bai Nican, EDETATE DISODIUM, oxine mixes, concrete composition percentage by weight is: Peracetic acid 4.0%-6.0%, hydrogen peroxide 18.0%-22.0%, Bai Nican 0.3%-1.5%, EDETATE DISODIUM 0.3%-1.0%, oxine 0.3%-1.0%, surplus is water.Publication number 103766377A (application number 201210416140.8) patent discloses a kind of citric acid decalcification disinfectant being applied in dialysis machine and water treatment and preparation method thereof, this disinfectant comprises polyhexamethylene guanide, citric acid, Gotu Kola P.E, malic acid, and surplus is deionized water.The component proportion of described disinfectant is polyhexamethylene guanide 0.001-5.0%, citric acid 10-50%, Gotu Kola P.E 20.0%-40%, malic acid 10% ~ 30%, surplus are deionized water.This disinfectant is that primary raw material is formulated by citric acid, polyhexamethylene guanide, Gotu Kola P.E and malic acid.Publication number 101664043 (application number 200910307991.7) patent discloses a kind of for sterilizing, the disinfectant of cleaning water channel of hemodialysis machine and preparation method thereof, be made up of citric acid, acid regulator, acid protease, high purity water and hydrogen peroxide; Wherein acid regulator sterilization, mass concentration in cleaning water channel of hemodialysis machine disinfectant be 2%-5%, the mass concentration of acid protease in sterilization, cleaning water channel of hemodialysis machine disinfectant be 3000-6000SAPU/100ml, the mass concentration of hydrogen peroxide in sterilization, cleaning water channel of hemodialysis machine disinfectant is 8%-10%, the mass concentration of citric acid in sterilization, cleaning water channel of hemodialysis machine disinfectant is 40%-50%.
As can be seen here, disinfectant is in cleaning Medical Devices, there is good bactericidal effect, but the prior art comprising above-mentioned patent document also comes with some shortcomings, first, existing correlation technique is also fewer, and the door do not had is for a kind of disinfectant for cleaning Internal Medicine-Cardiovascular Dept. oxygen mask.
Summary of the invention
The technical problem to be solved in the present invention overcomes the shortcoming for oxygen mask sterilization and disinfectant poor stability in prior art, an object of the present invention be to provide a kind of formula rationally, stable performance, easy to use, safety, nontoxic stability are preferably for the disinfectant of oxygen mask sterilization, and another object is just to provide the preparation method of above-mentioned disinfectant.
Above-mentioned purpose of the present invention is achieved through the following technical solutions:
For cleaning a disinfectant for Internal Medicine-Cardiovascular Dept. oxygen mask, comprise the composition of following weight content, Peracetic acid 1-3 part, hydrogen peroxide 1-5 part, metronidazole 3-6 part, phenol 4-9 part, Bai Nican 6-10 part, clorox 2-6 part, Gotu Kola P.E 1-5 part.
According to the foregoing disinfectant for cleaning Internal Medicine-Cardiovascular Dept. oxygen mask, preferred scheme is: the composition comprising following weight content: Peracetic acid 1.5-2.5 part, hydrogen peroxide 2-4 part, metronidazole 4-5 part, phenol 5-8 part, Bai Nican 7-9 part, clorox 3-5 part, Gotu Kola P.E 2-4 part.
According to the foregoing disinfectant for cleaning Internal Medicine-Cardiovascular Dept. oxygen mask, better preferred scheme is, comprises the composition of following weight content, Peracetic acid 2 parts, hydrogen peroxide 3 parts, metronidazole 4.5 parts, phenol 6 parts, Bai Nican 8 parts, clorox 4 parts, Gotu Kola P.E 3 parts.
According to the preparation method of the disinfectant for cleaning Internal Medicine-Cardiovascular Dept. oxygen mask above described in any one, comprise the following steps:
(1) be placed in marmite by Bai Nican, after adding 30-40 DEG C emerge in worm water 10-30 minute, be heated to 90 DEG C, add Gotu Kola P.E, together decoct 0.5-1.5 hour, filter, filtrate is for subsequent use;
(2) step (1) gained filtrate adds in special Agitation Tank together with metronidazole, Peracetic acid is added after mixing completely, leave standstill after 2-3 hour, stir at 20-40 DEG C after 0.5 hour and obtain buffer solution, then buffer solution is placed stand-by in the cool;
(3) hydrogen peroxide, phenol and clorox are joined in step (2) gained gained buffer solution, be slowly stirred to whole dissolving with waddy, bottle and obtain disinfectant.
According to foregoing preparation method, preferred scheme is: (preferably add the emerge in worm water of 35 DEG C after 20 minutes) after step (1) adds 33-38 DEG C emerge in worm water 15-25 minute.
According to foregoing preparation method, preferred scheme is: the consumption of step (1) warm water is that the 5-15 of the total consumption of Bai Nican is doubly (preferred, the consumption of warm water is 8-13 times of the total consumption of Bai Nican, more preferably good, the consumption of warm water is 10 times of the total consumption of Bai Nican).
According to foregoing preparation method, preferred scheme is: step (1) together decocts 0.8-1.3 hour (preferably together decocting 1 hour).
According to foregoing preparation method, preferred scheme is: step (2) left standstill after 2.3-2.8 hour, at 25-35 DEG C, stirring obtains buffer solution (preferred, to leave standstill after 2.5 hours, stir after 0.5 hour and obtain buffer solution at 30 DEG C) after 0.5 hour.
Being described below of each raw material:
Peracetic acid: be colourless liquid, has the typical scent of acetic acid.Peracetic acid is strong oxidizer.Medical industry is used as drinking-water, food and prevents the disinfectant of infectious disease.Peracetic acid is strong oxidizer, there is very strong oxidisability, meet organic matter release nascent oxygen and play oxidation, used by as medical treatment or life disinfecting drug with clorox (having another name called 84 disinfectants), bleaching powder etc., for efficient, quick-acting, low toxicity, wide-spectrum bactericide, all there is killing action to bacterial propagule, gemma, virus, mould.Therefore sterilization, sterilization can be carried out with it.In addition, because Peracetic acid has stronger volatility in atmosphere, carry out sterilization, sterilization has good effect, and low price to air, our sterilization when preventing SARS at present, disinfectant are exactly mainly Peracetic acid.
Hydrogen peroxide: hydrogen peroxide chemistry formula is H2O2, is commonly called as hydrogen peroxide.Outward appearance is colourless transparent liquid, is a kind of strong oxidizer, and its aqueous solution is applicable to medical wound sterilization and environment disinfected and food sterilization.Can resolve into water and oxygen in the ordinary course of things, but decomposition rate is extremely slow, the way accelerating its reaction velocity adds catalyzer---manganese dioxide or irradiate with short-wave ray.The purposes of hydrogen peroxide divides medical, military and industrial three kinds, daily sterilization be medical hydrogen peroxide, medical hydrogen peroxide can kill pathogenic entero becteria, pyococcus, and pathogenic yeast bacterium, is generally used for surface disinfection.Hydrogen peroxide has oxidation, but medical hydrogen peroxide concentration is equal to or less than 3%, wipes wound face, has burning sensation, surface is oxidized to white and emits bubble, just passable once by clean water, crosses and just recovers the original colour of skin in 3-5 minute.Chemical industry is used as the raw material producing sodium perborate, SODIUM PERCARBONATE, Peracetic acid, sodium chlorite, thiourea peroxide etc., the oxidant of tartaric acid, vitamin etc.Medical industry is used as bactericide, disinfectant, and produces the oxidant of tmtd insecticide and 401 antibacterial agents.Printing and dyeing industry is used as the bleaching agent of bafta, the colour former after reducing dye dyeing.De-iron and other heavy metals is removed for the production of when metallic salt or other compounds.Also for electroplate liquid, can inorganic impurity be removed, improve plating quality.Also for the bleaching of wool, raw silk, ivory, paper pulp, fat etc.The hydrogen peroxide of high concentration can be used as rocket-powered fuel.
Metronidazole: this chemicals of metronidazole Metronidazole is white or micro-yellow crystal or crystalline powder; Have micro-smelly, bitter and slightly salty.Slightly molten in ethanol, slightly soluble in water or chloroform, soluble,very slightly in ether.Fusing point is 159 DEG C one 163 DEG C.To most of anaerobic bacteria, there is powerful antibacterial action.Antimicrobial spectrum comprises bacteroides fragilis and belongs to and other Bacteroidess, fusiform bacilarmature, aerogenesis clostridium, Eubacterium, Wei Rong coccus, peptococcus and peptostreptococcus etc.The a little higher than bacteriostatic solution of its bacteriocidal concentration.The bactericidal mechanism of metronidazole is illustrated not yet completely, and the nitroreductase of anaerobic bacteria plays an important role in the energy metabolism of sensitive strain.
Phenol: phenol is a kind of colourless acicular crystal with special odor, poisonous is the important source material of producing some resin, bactericide, preservative and medicine (as aspirin).Also can be used for for surgical instruments and the excremental process of sterilizing, skin sterilization, antipruritic and tympanitis.Be slightly soluble in water under normal temperature, be soluble in organic solvent; When temperature is higher than 65 DEG C, can dissolve each other with arbitrary proportion with water.Phenol is corrosive, and can make local protein sex change after contact, and its solution is stained with available ethanol wash on skin.Phenol exposes and is oxidized by oxygen in atmosphere as quinone and pinkiness.
Bai Nican: in vitro test, during Bohadschia argus Jaeger saponin 3-100 μ g/ml, all there is very strong antifungic action to Candida albicans, candida tropicalis (Candida tropicalis), candida utili (C.utilis), candida krusei (C.krusei) etc.Isolated holothurin A from Bai Nican (Bohadschia graeffei), the external propagation that can suppress yeast completely, can kill tumour cell time heavy dose of completely.
Clorox: clorox, chemical formula NaClO is the hypochlorite of sodium.The hypochlorous acid that clorox and carbon dioxide reaction produce is the active ingredient of bleaching agent.Strong oxidizer, is used for papermaking, weaving, light industry etc. as bleaching agent, oxidant and water scavengine agent, has the effect of bleaching, sterilization, sterilization.
Gotu Kola P.E: jaundice with damp-heat pathogen, heatstroke is suffered from diarrhoea, and sand drenches blood and drenches, carbuncle sore tumefacting virus, injury from falling down.Centella can be compacted epidermis and corium coupling part, and skin can be made to limber up, and contributes to solving cutis laxa phenomenon (especially postpartum mother), makes skin smooth flexible; Help to promote that collagen is formed in skin corium, makes fibrin regenerate, reconnects, fundamentally elimination mother line, skin is reached compact smooth effect.Also can help impaired organization healing and consolidation skin.Can to promote between epidermis with corium close is connected, the increase of adipocyte can be suppressed again, prevent hydroderma, occur fat.Dicotyledon Umbelliferae, subdhing swelling and detoxicating is dispelled running sore.Centella can be compacted epidermis and corium coupling part, and skin can be made to limber up, and helps to promote that in skin corium, collagen is formed, and has the effect making skin compact.
The disinfectant appearance colorless of the oxygen mask sterilization of the present invention's development is transparent, physical and chemical index stable performance, has no crystallization, muddiness, precipitation during use, and every physical and chemical index performance is stable.Compared with prior art the present invention prepares that disinfectant production cost is low, preparation technology is simple, process conditions are easy to realize, and product stability is good.
Embodiment
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not by this restriction.
Embodiment 1 one kinds, for cleaning the disinfectant of Internal Medicine-Cardiovascular Dept. oxygen mask, comprises the composition of following weight content: Peracetic acid 1 gram, hydrogen peroxide 1 gram, metronidazole 3 grams, phenol 4 grams, Bai Nican 6 grams, clorox 2 grams, Gotu Kola P.E 1 gram.
A kind of preparation process of the disinfectant for cleaning Internal Medicine-Cardiovascular Dept. oxygen mask is as follows:
(1) be placed in marmite by Bai Nican, add the emerge in worm water of 30 DEG C after 10 minutes, the consumption of warm water is 5 times of the total consumption of Bai Nican, is heated to 90 DEG C, adds Gotu Kola P.E, together decocts 0.5 hour, and filter, filtrate is for subsequent use;
(2) step (1) gained filtrate adds in special Agitation Tank together with metronidazole, Peracetic acid is added after mixing completely, leave standstill after 2 hours, stir at 20 DEG C after 0.5 hour and obtain buffer solution, then buffer solution is placed stand-by in the cool;
(3) hydrogen peroxide, phenol and clorox are joined in step (2) gained gained buffer solution, be slowly stirred to whole dissolving with waddy, bottle and obtain disinfectant.
Stability test 1: get a kind of disinfectant for cleaning Internal Medicine-Cardiovascular Dept. oxygen mask of above-described embodiment 1 gained, stability test is carried out with reference to " disinfection technology standard " 2002 editions, storage condition: at 37 DEG C, testing environment: temperature 30 DEG C, relative moisture 40%-44%, result is as shown in table 1 below:
Table 1
Proved by 37 DEG C of accelerated tests, a kind of active ingredient Peracetic acid of the disinfectant for cleaning Internal Medicine-Cardiovascular Dept. oxygen mask and the content of hydrogen peroxide of embodiment 1 gained do not decline substantially, only have a small amount of hydrogen peroxide to decompose; Showing having good stability of a kind of disinfectant for cleaning Internal Medicine-Cardiovascular Dept. oxygen mask of the present invention, in storage and transportation, a large amount of decomposition can not occur.
Embodiment 2 one kinds, for cleaning the disinfectant of Internal Medicine-Cardiovascular Dept. oxygen mask, comprises the composition of following weight content: Peracetic acid 3 grams, hydrogen peroxide 5 grams, metronidazole 6 grams, phenol 9 grams, Bai Nican 10 grams, clorox 6 grams, Gotu Kola P.E 5 grams.
A kind of preparation process of the disinfectant for cleaning Internal Medicine-Cardiovascular Dept. oxygen mask is as follows:
(1) be placed in marmite by Bai Nican, add the emerge in worm water of 40 DEG C after 30 minutes, the consumption of warm water is 15 times of the total consumption of Bai Nican, is heated to 90 DEG C, adds Gotu Kola P.E, together decocts 1.5 hours, and filter, filtrate is for subsequent use;
(2) step (1) gained filtrate adds in special Agitation Tank together with metronidazole, Peracetic acid is added after mixing completely, leave standstill after 3 hours, stir at 40 DEG C after 0.5 hour and obtain buffer solution, then buffer solution is placed stand-by in the cool:
(3) hydrogen peroxide, phenol and clorox are joined in step (2) gained gained buffer solution, be slowly stirred to whole dissolving with waddy, bottle and obtain disinfectant.
Stability test 2: get a kind of disinfectant for cleaning Internal Medicine-Cardiovascular Dept. oxygen mask of above-described embodiment 2 gained, carries out stability test, storage condition with reference to " disinfection technology standard " 2002 editions: 37 DEG C of placements.Testing environment: temperature 30 DEG C, relative moisture 40%-44%.Result is as shown in table 2 below:
Table 2
Proved by 37 DEG C of accelerated tests, a kind of active ingredient Peracetic acid of the disinfectant for cleaning Internal Medicine-Cardiovascular Dept. oxygen mask and the content of hydrogen peroxide of embodiment 2 gained do not decline substantially, only have a small amount of hydrogen peroxide to decompose; Showing having good stability of a kind of disinfectant for cleaning Internal Medicine-Cardiovascular Dept. oxygen mask of the present invention, in storage and transportation, a large amount of decomposition can not occur.
Embodiment 3 one kinds, for cleaning the disinfectant of Internal Medicine-Cardiovascular Dept. oxygen mask, comprises the composition of following weight content: Peracetic acid 1.5 grams, hydrogen peroxide 2 grams, metronidazole 4 grams, phenol 5 grams, Bai Nican 7 grams, clorox 3 grams, Gotu Kola P.E 2 grams.
A kind of preparation process of the disinfectant for cleaning Internal Medicine-Cardiovascular Dept. oxygen mask is as follows:
(1) be placed in marmite by Bai Nican, add the emerge in worm water of 33 DEG C after 15 minutes, the consumption of warm water is 8 times of the total consumption of Bai Nican, is heated to 90 DEG C, adds Gotu Kola P.E, together decocts 0.8 hour, and filter, filtrate is for subsequent use;
(2) step (1) gained filtrate adds in special Agitation Tank together with metronidazole, Peracetic acid is added after mixing completely, leave standstill after 2.3 hours, stir at 25 DEG C after 0.5 hour and obtain buffer solution, then buffer solution is placed stand-by in the cool;
(3) hydrogen peroxide, phenol and clorox are joined in step (2) gained gained buffer solution, be slowly stirred to whole dissolving with waddy, bottle and obtain disinfectant.
Stability test 3: get a kind of disinfectant for cleaning Internal Medicine-Cardiovascular Dept. oxygen mask prepared by above-described embodiment 3, carries out stability test, storage condition with reference to " disinfection technology standard " 2002 editions: place at 37 DEG C.Testing environment: temperature 30 DEG C, relative moisture 40%-44%.Result is as shown in table 3 below:
Table 3
Proved by 37 DEG C of accelerated tests, a kind of active ingredient Peracetic acid of the disinfectant for cleaning Internal Medicine-Cardiovascular Dept. oxygen mask and the content of hydrogen peroxide of embodiment 3 gained do not decline substantially, only have a small amount of hydrogen peroxide to decompose; Showing having good stability of a kind of disinfectant for cleaning Internal Medicine-Cardiovascular Dept. oxygen mask of the present invention, in storage and transportation, a large amount of decomposition can not occur.
Embodiment 4 one kinds, for cleaning the disinfectant of Internal Medicine-Cardiovascular Dept. oxygen mask, comprises the composition of following weight content: Peracetic acid 2.5 grams, hydrogen peroxide 4 grams, metronidazole 5 grams, phenol 8 grams, Bai Nican 9 grams, clorox 5 grams, Gotu Kola P.E 4 grams.
A kind of preparation process of the disinfectant for cleaning Internal Medicine-Cardiovascular Dept. oxygen mask is as follows:
(1) be placed in marmite by Bai Nican, add the emerge in worm water of 38 DEG C after 25 minutes, the consumption of warm water is 13 times of the total consumption of Bai Nican, is heated to 90 DEG C, adds Gotu Kola P.E, together decocts 1.3 hours, and filter, filtrate is for subsequent use;
(2) step (1) gained filtrate adds in special Agitation Tank together with metronidazole, Peracetic acid is added after mixing completely, leave standstill after 2.8 hours, stir at 35 DEG C after 0.5 hour and obtain buffer solution, then buffer solution is placed stand-by in the cool;
(3) hydrogen peroxide, phenol and clorox are joined in step (2) gained gained buffer solution, be slowly stirred to whole dissolving with waddy, bottle and obtain disinfectant.
Embodiment 5 one kinds, for cleaning the disinfectant of Internal Medicine-Cardiovascular Dept. oxygen mask, comprises the composition of following weight content, Peracetic acid 2 grams, hydrogen peroxide 3 grams, metronidazole 4.5 grams, phenol 6 grams, Bai Nican 8 grams, clorox 4 grams, Gotu Kola P.E 3 grams.
A kind of preparation process of the disinfectant for cleaning Internal Medicine-Cardiovascular Dept. oxygen mask is as follows:
(1) be placed in marmite by Bai Nican, add the emerge in worm water of 35 DEG C after 20 minutes, the consumption of warm water is 10 times of the total consumption of Bai Nican, is heated to 90 DEG C, adds Gotu Kola P.E, together decocts 1 hour, and filter, filtrate is for subsequent use;
(2) step (1) gained filtrate adds in special Agitation Tank together with metronidazole, Peracetic acid is added after mixing completely, leave standstill after 2.5 hours, stir at 30 DEG C after 0.5 hour and obtain buffer solution, then buffer solution is placed stand-by in the cool;
(3) hydrogen peroxide, phenol and clorox are joined in step (2) gained gained buffer solution, be slowly stirred to whole dissolving with waddy, bottle and obtain disinfectant.
Experimental example 1: to embodiment 5 prepare disinfectant with the sterilization Simulation field test to oxygen mask such as hemolytic streptococcus, pneumococcus, proteus, Escherichia coli:
Get hemolytic streptococcus respectively, pneumococcus, proteus, Escherichia coli suspension drip and contaminate in the coating of polyfluortetraethylene pipe inside evenly, be placed in 37 DEG C of constant incubators dry, prepare bacterial carrier.With the product of gained of the present invention for disinfectant, carry out cleaning and sterilizing according to oxygen mask sterilisation step, result is as shown in table 4 below:
This disinfectant of table 4 is to the kill oncomelania of bacterium
Result shows this product to the hemolytic streptococcus contaminated on polyfluortetraethylene pipe, pneumococcus, proteus, colibacillary kill oncomelania > 5.89, shows that this product has good disinfection effect.
Experimental example 2: in order to verify the disinfection effect of embodiment 5 gained disinfectant, get hemolytic streptococcus respectively, pneumococcus, proteus, Escherichia coli suspension drip and contaminate in the coating of polyfluortetraethylene pipe inside evenly, be placed in 37 DEG C of constant incubators dry, prepare bacterial carrier.By the bacterial carrier prepared, be divided into two groups, experimental group and control group, experimental group uses the product of gained of the present invention for disinfectant, cleaning and sterilizing is carried out according to oxygen mask sterilisation step, control group is with other disinfectants to oxygen mask sterilization (the such as routine disinfection agent such as lysol, 84 disinfectants), and result is as shown in table 5 below:
Table 5 is for gained disinfectant of the present invention is to the kill oncomelania of bacterium
Result: two groups of sterilization comparitive study, this product is to the hemolytic streptococcus contaminated on polyfluortetraethylene pipe, pneumococcus, proteus and colibacillary kill oncomelania > 5.89, obvious bactericidal effect is better than control group, shows that this product has good disinfection effect.
With reference to embodiments of the invention, explanation is given to the present invention above.But these embodiments are only for illustrative purposes, and are not intended to limit the scope of the invention.Scope of the present invention is by claims and equivalents thereof.Do not depart from the scope of the present invention, those skilled in the art can make a variety of substitutions and modifications, and these substitutions and modifications all should fall within the scope of the present invention.

Claims (8)

1. for cleaning a disinfectant for Internal Medicine-Cardiovascular Dept. oxygen mask, it is characterized in that: the composition comprising following weight content, Peracetic acid 1-3 part, hydrogen peroxide 1-5 part, metronidazole 3-6 part, phenol 4-9 part, Bai Nican 6-10 part, clorox 2-6 part, Gotu Kola P.E 1-5 part.
2. the disinfectant for cleaning Internal Medicine-Cardiovascular Dept. oxygen mask according to claim 1, it is characterized in that: the composition comprising following weight content: Peracetic acid 1.5-2.5 part, hydrogen peroxide 2-4 part, metronidazole 4-5 part, phenol 5-8 part, Bai Nican 7-9 part, clorox 3-5 part, Gotu Kola P.E 2-4 part.
3. the disinfectant for cleaning Internal Medicine-Cardiovascular Dept. oxygen mask according to claim 1, is characterized in that, comprises the composition of following weight content, Peracetic acid 2 parts, hydrogen peroxide 3 parts, metronidazole 4.5 parts, phenol 6 parts, Bai Nican 8 parts, clorox 4 parts, Gotu Kola P.E 3 parts.
4. the preparation method of the disinfectant for cleaning Internal Medicine-Cardiovascular Dept. oxygen mask according to any one of claim 1-3, is characterized in that: comprise the following steps:
(1) be placed in marmite by Bai Nican, after adding 30-40 DEG C emerge in worm water 10-30 minute, be heated to 90 DEG C, add Gotu Kola P.E, together decoct 0.5-1.5 hour, filter, filtrate is for subsequent use;
(2) step (1) gained filtrate adds in special Agitation Tank together with metronidazole, Peracetic acid is added after mixing completely, leave standstill after 2-3 hour, stir at 20-40 DEG C after 0.5 hour and obtain buffer solution, then buffer solution is placed stand-by in the cool;
(3) hydrogen peroxide, phenol and clorox are joined in step (2) gained gained buffer solution, be slowly stirred to whole dissolving with waddy, bottle and obtain thimerosal.
5. preparation method according to claim 4, is characterized in that: (preferably add the emerge in worm water of 35 DEG C after 20 minutes) after step (1) adds 33-38 DEG C emerge in worm water 15-25 minute.
6. preparation method according to claim 4, it is characterized in that: the consumption of step (1) warm water is that the 5-15 of the total consumption of Bai Nican is doubly (preferred, the consumption of warm water is 8-13 times of the total consumption of Bai Nican, more preferably good, the consumption of warm water is 10 times of the total consumption of Bai Nican).
7. preparation method according to claim 4, is characterized in that: step (1) together decocts 0.8-1.3 hour (preferably together decocting 1 hour).
8. preparation method according to claim 4, it is characterized in that: step (2) left standstill after 2.3-2.8 hour, at 25-35 DEG C, stirring obtains buffer solution (preferred, to leave standstill after 2.5 hours, stir after 0.5 hour and obtain buffer solution at 30 DEG C) after 0.5 hour.
CN201410478508.2A 2014-09-19 2014-09-19 Disinfectant fluid for cleaning oxygen mask for cardiovascular internal medicine and preparation method thereof Pending CN104509552A (en)

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CN104982458A (en) * 2015-06-30 2015-10-21 苏州乔纳森新材料科技有限公司 Medical rust-proof sanitizer and preparation method thereof
CN105707129A (en) * 2016-01-25 2016-06-29 五河县永明食品有限公司 Live pig slaughter house slaughter appliance soaking fluid and preparation method thereof
CN105707130A (en) * 2016-01-25 2016-06-29 五河县永明食品有限公司 Live pig slaughter house appliance sterilizing fluid and preparation method thereof

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