CN104491559A - Traditional Chinese medicine for treating deficient speech and Qi caused allergic rhinitis - Google Patents

Traditional Chinese medicine for treating deficient speech and Qi caused allergic rhinitis Download PDF

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CN104491559A
CN104491559A CN201510018980.2A CN201510018980A CN104491559A CN 104491559 A CN104491559 A CN 104491559A CN 201510018980 A CN201510018980 A CN 201510018980A CN 104491559 A CN104491559 A CN 104491559A
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chinese medicine
herba
allergic rhinitis
radix
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王瑞红
陈加峰
陈仁霞
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • A61K36/076Poria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/24Apocynaceae (Dogbane family), e.g. plumeria or periwinkle
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/51Gentianaceae (Gentian family)
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/69Polygalaceae (Milkwort family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches

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  • Health & Medical Sciences (AREA)
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Abstract

The invention provides a traditional Chinese medicine for treating deficient speech and Qi caused allergic rhinitis. The traditional Chinese medicine is prepared from pedicularis muscicola, euphorbia humifusa, japanese tripterospermum herb, pearly everlasting, plumeria rubra, poria cocos, bauhinia hupehana craib, herb of palmgrass, polygala koi and liquorice. The traditional Chinese medicine is clinically applied to treatment of deficient speech and Qi caused allergic rhinitis.

Description

A kind of Chinese medicine for the treatment of insufficiency of spleen-qi type allergic rhinitis
Technical field
The invention belongs to technical field of Chinese medicines, especially relate to a kind of Chinese medicine for the treatment of insufficiency of spleen-qi type allergic rhinitis.
Background technology
Allergic rhinitis (allergic rhinitis, AR) allergic rhinitis are called for short, also known as allergic rhinitis, be a kind of contact sensitization allergen by susceptible individual after the nasal mucosa chronic inflammation disease that participates in of the release comprising the inflammatory mediator that IgE mediates that causes and panimmunity competent cell, cytokine, point perennially with seasonal two kinds, the former is more than the latter, and sickness rate accounts for crowd's.The symptoms such as its main clinical manifestation is repeatedly, break out nasal obstruction, sneeze, rhinocnesmus, nose hypersecretion and olfactory function obstacle.Patient clinical symptom is rhinocnesmus, sneeze, snivel, nasal obstruction, even hyposmia, tunica mucosa nasi swelling, color are pale, breathe hard with nose heave, dizzy, Mental fatigue, face light yellow complexion or white, extremity are sleepy, poor appetite, abdominal distention loose stool, pale tongue is fat, while there is indentation, tongue is white, relaxed and soft pulse.The Therapeutic Method that current doctor trained in Western medicine is commonly used comprises use antihistaminic, local glucocorticoid, and specific immunotherapy.Although Therapeutic Method is numerous, curative effect is satisfaction not to the utmost, often more recurs, recurrent exerbation, is difficult to radical cure.Inventor draws through long-term practice and adopts treatment by Chinese herbs insufficiency of spleen-qi type allergic rhinitis, can pass through regulating functions of ZANG FU-organs, reach the object of strengthening vital QI to eliminate pathogenic factors, giving consideration to both the incidental and fundamental, thus can obtain long-term curative effect.
Summary of the invention
The object of the present invention is to provide that a kind of therapeutic effect is good, effective percentage is high, Chinese medicine to the treatment insufficiency of spleen-qi type allergic rhinitis of human non-toxic's side effect.
The object of the present invention is achieved like this, according to Chinese medical theory, utilize the property of medicine of Chinese medicine uniqueness, adopt Radix pedicularis muscicolae, Crepis crocea Babc.(C.turczaninowii C.A.Mey.), Herba Tripterospermi japonici, Herba Anaphalidis Margaritaceae, Flos Plumeriae Acutifoliae, Poria, Radix Bauhiniae Hupehanae, Herba Setariae palmifoliae, a bag flower, Radix Glycyrrhizae, according to certain compatibility requirement, through being processed into.
Prepare Chinese medicine of the present invention to be made up of following raw material medicaments: Radix pedicularis muscicolae 30-40 part, Crepis crocea Babc.(C.turczaninowii C.A.Mey.) 20-30 part, Herba Tripterospermi japonici 20-30 part, Herba Anaphalidis Margaritaceae 10-20 part, Flos Plumeriae Acutifoliae 10-20 part, Poria 10-20 part, Radix Bauhiniae Hupehanae 10-20 part, Herba Setariae palmifoliae 10-20 part, a bag flower 10-20 part, Radix Glycyrrhizae 5-10 part.
Optimum weight part of raw material of Chinese medicine medicine of the present invention is: Radix pedicularis muscicolae 35 parts, Crepis crocea Babc.(C.turczaninowii C.A.Mey.) 25 parts, Herba Tripterospermi japonici 25 parts, Herba Anaphalidis Margaritaceae 15 parts, Flos Plumeriae Acutifoliae 15 parts, 15 parts, Poria, Radix Bauhiniae Hupehanae 15 parts, Herba Setariae palmifoliae 15 parts, a bag spend 15 parts, 8 parts, Radix Glycyrrhizae.
The pharmacological action of Chinese medicine of the present invention is as follows:
Radix pedicularis muscicolae: sweet, bitter, warm.Return spleen, heart channel.Invigorating QI to consolidate the body surface resistance, calms the nerves.Clinical in insufficiency of vital energy and blood, the empty hyperhidrosis of body, cardiopalmus is weak waits disease.
Crepis crocea Babc.(C.turczaninowii C.A.Mey.): bitter, sweet, warm.Liver and kidney tonifying, invigorating spleen to remove dampness.For having a dizzy spell, soreness of the waist and knees, edema, leukorrhagia infantile malnutrition, hypogalactia etc.
Herba Tripterospermi japonici: pungent, bitter, cool.Return lung, liver, spleen channel.Wind and heat dispersing; Invigorating spleen to remove dampness; Parasite killing.Cough due to pathogenic wind-heat; Jaundice; Rheumatic arthralgia; Ascariasis.
Herba Anaphalidis Margaritaceae: bitter, pungent, cool.Clearing away heat-fire, dampness, anthelmintic.For toothache, damp-heat dysentery, ascariasis, the diseases such as scrofula.
Flos Plumeriae Acutifoliae: sweet, micro-hardship, cool.Return lung, large intestine channel.Heat clearing away, dampness removing, expelling summer-heat.For cold, fever, cough due to lung-heat, jaundice due to damp-heat, dysentery, lithangiuria, prevention heatstroke.
Poria: sweet, light, flat.GUIXIN, spleen, lung, kidney channel.Eliminating dampness and diuresis, invigorating the spleen and regulating the stomach, mind tranquilizing and the heart calming.For dysuria, edema distension, phlegm retention cough with dyspnea, vomiting, insufficiency of the spleen lack of appetite, has loose bowels, palpitation and restlessness, insomnia forgetfulness, seminal emission nebulousurine etc.
Radix Bauhiniae Hupehanae: puckery, flat.Return kidney, large intestine channel.Restrain astringent or styptic treatment for spontaneous sweating, removing toxic substances dehumidifying.Clinical in hemoptysis of coughing, spit blood, have blood in stool, the enuresis, frequent micturition, uterine prolapse, dysentery, arthralgia pain, hernia, the diseases such as painful and swollen testis.
Herba Setariae palmifoliae: sweet, warm.Return spleen channel.Supplementing QI to prevent collapse.Clinical in proctoptosis, the diseases such as uterine prolapse.
One bag flower: pungent, bitter, flat.Preventing phlegm from forming and stopping coughing, promoting blood flow to regulate menstruation.For cough with copious phlegm, laryngopharynx swelling and pain, traumatic injury, the diseases such as menoxenia.
Radix Glycyrrhizae: sweet, flat, GUIXIN, lung, spleen, stomach warp.QI invigorating invigorating middle warmer, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, the mediation property of medicine.For severe palpitation, the irregularly intermittent and regularly intermittent pulse of deficiency of heart-QI, pathopyretic ulcer, laryngopharynx swelling and pain.
Insufficiency of spleen-qi type allergic rhinitis belong to Chinese medicine " allergic rhinitis " category.Itself and lung, spleen, kidney three deficiency of five ZANG-organs damage, and positive QI-insufficiency is relevant.Nose is the upper orifices of lung, and insufficiency of lung-QI is striae of the skin and muscles being loose then, instability of surface, easily makes the heresy invasion and attack nose key of wind and cold, unusual pathogen, pathogen conflicting with vital QI, so cause Lung Qi obstraction, body fluid stops gathering, and occurs the symptoms such as paroxysmal sneeze, watery nasal discharge, nasal obstruction.The spleen has the function to transport and transform nutrients, deficiency-weakness of spleen-QI, and change raw not enough, then nose key loses and supports, and is subject to heresy and invades; The spleen has the function to transport and transform nutrients water liquid, insufficiency of the spleen, water is wet not to be transported, and stops poly-nose key, causes nasal obstruction, watery nasal discharge, hypertrophic inferior turbinate.Radix pedicularis muscicolae invigorating QI to consolidate the body surface resistance in the present invention, calming the nerves, is our monarch drug, Crepis crocea Babc.(C.turczaninowii C.A.Mey.) liver and kidney tonifying, invigorating spleen to remove dampness, and Herba Tripterospermi japonici wind and heat dispersing, invigorating spleen to remove dampness are ministerial drug; Herba Anaphalidis Margaritaceae clearing away heat-fire, dampness, Flos Plumeriae Acutifoliae heat clearing away, dampness removing, Poria eliminating dampness and diuresis, invigorating the spleen and regulating the stomach, Radix Bauhiniae Hupehanae convergence is astringent or styptic treatment for spontaneous sweating, removing toxic substances dehumidifying, Herba Setariae palmifoliae QI invigorating, one bag flower reduces phlegm and invigorates blood circulation, the invigorating middle warmer of Radix Glycyrrhizae QI invigorating, coordinating the actions of various ingredients in a prescription, share and play the diuretic that dries altogether, replenishing QI to invigorate the spleen, removing toxic substances calm the nerves, effect of clearing the nasal passage, find, to insufficiency of spleen-qi type allergic rhinitis, there is unique curative effect through clinical practice.
Chinese medicine of the present invention was in 2007 to 2012 the routine patients of clinical observation insufficiency of spleen-qi type allergic rhinitis 54, and clinical report is as follows:
1, physical data
In 54 routine patients, male 22 example, women 32 example, 35.8 years old mean age.
2, diagnostic criteria
" Chinese medical disease Standardization of diagnosis and curative effect " with reference to State Administration of Traditional Chinese Medicine issues:
1. with paroxysmal rhinocnesmus, continuous sneeze, nasal obstruction, the clear rare amount of nasal mucus mostly is cardinal symptom.The disease such as to itch with anodimia, ophthalmic pruritus, throat.2. onset is rapid.The general last for several minutes of symptom is to several tens minutes.Intermission is without sneeze and nasal obstruction.Can the disease such as concurrent urticaria, asthma.3. often fall ill because the contact sensitizer such as pollen, flue dust, chemical gas, variation of ambient temperature also can be brought out sometimes.4. nasal cavity checks that mucosa mostly is pale, and minority is congested, concha nasalis swelling.More secretions is had during outbreak.
Insufficiency of spleen-qi type allergic rhinitis clinical symptoms is rhinocnesmus, sneeze, snivel, nasal obstruction, even hyposmia, tunica mucosa nasi swelling, color are pale, breathe hard with nose heave, dizzy, Mental fatigue, face light yellow complexion or white, extremity are sleepy, poor appetite, abdominal distention loose stool, pale tongue is fat, while there is indentation, tongue is white, relaxed and soft pulse.
3, Therapeutic Method
3.1 prescriptions: Radix pedicularis muscicolae 35g, Crepis crocea Babc.(C.turczaninowii C.A.Mey.) 25g, Herba Tripterospermi japonici 25g, Herba Anaphalidis Margaritaceae 15g, Flos Plumeriae Acutifoliae 15g, Poria 15g, Radix Bauhiniae Hupehanae 15g, Herba Setariae palmifoliae 15g, bag flower 15g, a Radix Glycyrrhizae 8g.
3.2 methods of preparation and use: said medicine routinely technique makes decoction, every day 1 dose, every day 2 times 7 days was 1 course for the treatment of.
4, therapeutic outcome
4.1 criterions of therapeutical effect are drafted with reference to State Administration of Traditional Chinese Medicine's " Chinese medical disease Standardization of diagnosis and curative effect ":
Cure: nasal obstruction, rhinocnesmus and sneeze transference cure, bronchia mucosal is light red or grey dim, nasal cavity secretions without exception;
Effective: nasal obstruction, rhinocnesmus, sneeze and snivel symptom obviously alleviate or disappear, occasionally can occur after only catching cold, bronchia mucosal is light red or grey dim, nasal cavity secretions without exception, or has a little glutinous white tears;
Effective: nasal obstruction, sneeze and snivel symptom comparatively before alleviate, and the pale ash of nasal mucosa is dim or light red;
Invalid: symptom after taking medicine is unchanged.
4.2 results: in 54 routine patients, cure 21 examples (38.9%), effective 16 examples (29.6%), effective 12 examples (22.2%), and invalid 5 examples (9.3%), total effective rate is 90.7%.
5, model case
5.1 weeks certain, man, 31 years old, sneeze recurrent exerbation, thin nasal discharge amount was many, rhinocnesmus, meets cold increasing the weight of, easy catching a cold, checks: nasal mucosa color is light, pale complexion, loose stool, light red tongue, and tongue is white, relaxed and soft pulse.Take medicine of the present invention, treat 1 course for the treatment of, rhinocnesmus, sneeze, snivel disappear all substantially, and symptom is obviously improved; Continue to take 2 courses for the treatment of, transference cure, body of the tongue is normal, follows up a case by regular visits to without recurrence after half a year.
5.2 Xiaos, female, 45 years old, nasal obstruction, time have thin nasal discharge, nose anemophobia is obvious, meet cold after have sneeze, without fever with chills.Check: nasal mucosa flushing, two concha nasalis inferior swelling, extremity are sleepy, light red tongue, and tongue is white, weak pulse.Take medicine of the present invention, every day 1 dose, after 1 course for the treatment of, occasionally there is nasal obstruction at night, and sneeze, thin nasal discharge disappear all substantially, faint and rapid pulse, and body of the tongue is normal, and continue to take 1 course for the treatment of, all diseases are removed entirely, and recovery from illness is followed up a case by regular visits to after 1 year without recurrence.
5.3 Feng, man, 51 years old, sneeze was frequently done, the turbid tears of wake, and amount is many, time have cough, cough white rare expectorant, after meeting cold air or penetrating odor, exacerbation of symptoms, breathes hard with nose heave, dizzy, Mental fatigue, light red tongue, white and thin fur, deficient and weak pulse.Take medicine of the present invention, treat 1 course for the treatment of, play attack times morning, watery nasal discharge obviously reduces, rhinocnesmus, sneeze minor responses.Continue to take 2 courses for the treatment of, clean in nasal meatus, without turbid tears, nasal airflow can, without rhinocnesmus, two just normally, recover.Follow up a case by regular visits to after half a year without recurrence.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is further illustrated, and this embodiment following does not only limit the present invention for illustration of the present invention.
Embodiment 1, treating a Chinese medicine for insufficiency of spleen-qi type allergic rhinitis, is be made up of Radix pedicularis muscicolae 30g, Crepis crocea Babc.(C.turczaninowii C.A.Mey.) 20g, Herba Tripterospermi japonici 20g, Herba Anaphalidis Margaritaceae 10g, Flos Plumeriae Acutifoliae 10g, Poria 10g, Radix Bauhiniae Hupehanae 10g, Herba Setariae palmifoliae 10g, bag flower 10g, a Radix Glycyrrhizae 5g.
Embodiment 2, treating a Chinese medicine for insufficiency of spleen-qi type allergic rhinitis, is be made up of Radix pedicularis muscicolae 35g, Crepis crocea Babc.(C.turczaninowii C.A.Mey.) 25g, Herba Tripterospermi japonici 25g, Herba Anaphalidis Margaritaceae 15g, Flos Plumeriae Acutifoliae 15g, Poria 15g, Radix Bauhiniae Hupehanae 15g, Herba Setariae palmifoliae 15g, bag flower 15g, a Radix Glycyrrhizae 8g.
Embodiment 3, treating a Chinese medicine for insufficiency of spleen-qi type allergic rhinitis, is be made up of Radix pedicularis muscicolae 40g, Crepis crocea Babc.(C.turczaninowii C.A.Mey.) 30g, Herba Tripterospermi japonici 30g, Herba Anaphalidis Margaritaceae 20g, Flos Plumeriae Acutifoliae 20g, Poria 20g, Radix Bauhiniae Hupehanae 20g, Herba Setariae palmifoliae 20g, bag flower 20g, a Radix Glycyrrhizae 10g.

Claims (2)

1. treat a Chinese medicine for insufficiency of spleen-qi type allergic rhinitis, it is characterized in that it is made up of following raw material medicaments:
Radix pedicularis muscicolae 30-40 part, Crepis crocea Babc.(C.turczaninowii C.A.Mey.) 20-30 part, Herba Tripterospermi japonici 20-30 part, Herba Anaphalidis Margaritaceae 10-20 part, Flos Plumeriae Acutifoliae 10-20 part, Poria 10-20 part, Radix Bauhiniae Hupehanae 10-20 part, Herba Setariae palmifoliae 10-20 part, a bag flower 10-20 part, Radix Glycyrrhizae 5-10 part.
2. Chinese medicine according to claim 1, is characterized in that it is made up of following raw material medicaments:
Radix pedicularis muscicolae 35 parts, Crepis crocea Babc.(C.turczaninowii C.A.Mey.) 25 parts, Herba Tripterospermi japonici 25 parts, Herba Anaphalidis Margaritaceae 15 parts, Flos Plumeriae Acutifoliae 15 parts, 15 parts, Poria, Radix Bauhiniae Hupehanae 15 parts, Herba Setariae palmifoliae 15 parts, a bag spend 15 parts, 8 parts, Radix Glycyrrhizae.
CN201510018980.2A 2015-01-15 2015-01-15 Traditional Chinese medicine for treating deficient speech and Qi caused allergic rhinitis Pending CN104491559A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102145061A (en) * 2011-04-07 2011-08-10 天津东方华康医药科技发展有限公司 Qidan nasal allergy medicament and preparation method thereof
CN103432475A (en) * 2013-09-06 2013-12-11 梁怡芃 Traditional Chinese medicine composition for treating allergic rhinitis and preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102145061A (en) * 2011-04-07 2011-08-10 天津东方华康医药科技发展有限公司 Qidan nasal allergy medicament and preparation method thereof
CN103432475A (en) * 2013-09-06 2013-12-11 梁怡芃 Traditional Chinese medicine composition for treating allergic rhinitis and preparation method thereof

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
朱玉琴: "过敏性鼻炎-过敏性鼻炎当责之肺脾肾", 《河南中医》 *
金慧鸣: "辨证治疗变应性鼻炎86例", 《中华中医药杂志》 *

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Application publication date: 20150408