CN104491106A - Traditional Chinese medicinal preparation for preventing and treating clostridiosis of sheep - Google Patents

Abstract

The invention relates to a traditional Chinese medicinal preparation for preventing and treating clostridiosis of sheep. The traditional Chinese medicinal preparation for preventing and treating the clostridiosis of the sheep is compounded by the following raw materials: astragalus, sanguisorba officinalis, cortex phellodendri, fructus forsythiae, frankincense, eucommia ulmoides leaves, coptis chinensis and radix paeoniae alba. The invention also provides a preparation method of the traditional Chinese medicinal preparation for realizing a better effect of preventing and treating the clostridiosis of the sheep. The preparation method of the traditional Chinese medicinal preparation comprises the following steps: firstly, removing impurities from the following raw materials: astragalus, sanguisorba officinalis, cortex phellodendri, fructus forsythiae, frankincense, eucommia ulmoides leaves, coptis chinensis and radix paeoniae alba, rapidly elutriating with cold boiled water, and airing; secondly, decocting the raw materials obtained in the step one with water on a slow fire, thus the traditional Chinese medicinal preparation is obtained. The traditional Chinese medicinal preparation for preventing and treating the clostridiosis of the sheep is mainly applied to prevention and treatment of the clostridiosis of the sheep, can be used for enhancing autoimmunity and disease resistance of the sheep and has anti-bacterial and anti-inflammation effects.

Description

The Chinese medicine preparation of control sheep clostridium property disease

Technical field

The present invention relates to the field of Chinese medicines, be specifically related to a kind of Chinese medicine preparation preventing and treating sheep clostridium property disease; Mainly as prevention and the treatment of sheep clostridium property disease, sheep autoimmunity and premunition can be strengthened, there is effect of anti-inflammation.

Background technology

Sheep clostridium property disease is the class disease caused by the microorganism in Clostridium.Comprise sheep braxy, Intestinum caprae seu ovis toxemia, sheep struck, lamb dysentery disease, lamb dysentery etc.Sheep braxy mainly betides a kind of acute infectious disease of sheep.Cause of disease is clostridium septicum, is to be caused by gram-positive lonely escherichia coli year, and suddenly, the course of disease is extremely short, and it is characterized by abomasum is hemorrhagic, inflammatory damage in morbidity.Intestinum caprae seu ovis toxemia is the sheep acute infectious disease that clostridieum welchii produces caused by toxin.This disease is with urgency of falling ill, and dead fast, after death kidney is common softens as feature.Also known as pulpy kidney disease, the fast epidemic disease of class.Sheep macaque of quenching is microbial by C type aerogenesis capsule bar, take acute death as feature, with peritonitis and ulcerative enteritis, 1-2 year sheep is multiple.Intestinum caprae seu ovis toxemia be by D type or C type aerogenesis capsule bar microbial, rapid onset, spirit is depressed, and appetite is useless absolutely, and diarrhoea, muscle spasm, falls down to the ground, extremity spasm, opisthotonus, and body temperature is not high.Cut open when picking up, kidney is soft as mud, is again the fast epidemic disease of class or pulpy kidney disease, normal sudden death.Sheep black disease disease has another name called infectious necrotic hepatitis, is the one acute height lethal toxemia of sheep and goat.Lamb dysentery is the acute toxemia of one of new-bom lamb, is its feature acutely to suffer from diarrhoea with small intestinal generation ulcer.Primary disease often can make lamb that large quantities of death occurs, and carrys out heavy losses to sheep raising industrial belt.

Summary of the invention

The object of the present invention is to provide a kind of Chinese medicine preparation preventing and treating sheep clostridium property disease; Mainly as prevention and the treatment of sheep clostridium property disease, sheep autoimmunity and premunition can be strengthened, there is effect of anti-inflammation.

For achieving the above object, present invention employs following technical scheme: the present invention prevents and treats the Chinese medicine preparation of sheep clostridium property disease, it is characterized in that, combined by the former material spice Radix Astragali, Radix Sanguisorbae, Cortex Phellodendri, Fructus Forsythiae, Olibanum, Folium Eucommiae, Rhizoma Coptidis, the Radix Paeoniae Alba.

For reaching better prevention and the effect for the treatment of sheep clostridium property disease, present invention also offers the preparation method of this Chinese medicine preparation;

Its preparation method is following steps: step one), by the raw medicinal material Radix Astragali, Radix Sanguisorbae, Cortex Phellodendri, Fructus Forsythiae, Olibanum, Folium Eucommiae, Rhizoma Coptidis, the Radix Paeoniae Alba remove impurity, eluriate rapidly with cold boiled water water, dry;

Step 2), step one) water slow fire is fried altogether for the raw medicinal material that obtains, obtains Chinese medicine preparation.

Using method: obtained Chinese medicine preparation and water 3: 5 are fed rearing sheep in pens.

In the raw materials of traditional Chinese medicinal materials that the present invention chooses, its effect and pharmacological action respectively:

The Radix Astragali: have 1, an exterior deficiency spontaneous perspiration, is used for the weak caused spontaneous perspiration of body void table.2, night sweat due to yin deficiency; 3, acute nephritis edema, for the void edema caused by YANG QI deficiency; 4, oedema due to chronic nephritis, spleen person who suffer from deficiency of kidney Yang; 5, yang-energy is weak, caves in, have and promote diabrosis and limitation effect for skin infection not diabrosis for a long time.6, skin infection is burst for a long time and is not healed, and after skin infection diabrosis, does not close up for a long time, has the effect of promoting tissue regeneration and wound healing; 7, syndrome of deficiency of spleen qi, weak asthenia, has loose bowels, sinking of QI of middle-JIAO, and internal organs prolapse, the indigestion and loss of appetite all diseases of lack of appetite.8, syndrome of deficiency of lung qi.With the passing of time, shortness of breath and tired spirit, expectorant harmony brings up in lung is unable cough with asthma.9, hyperhidrosis and edema.10, weak for the deficiency of vital energy, fatigue and weakness, or sinking of QI of middle-JIAO, proctoptosis, uterine prolapse.Nature and flavor: sweet, tepor.Gui Jing: return lung, spleen, liver, kidney channel; Have enhancing human body immunity function, protect the liver, diuresis, defying age, anti-stress, blood pressure lowering and antibacterial action more widely.

Radix Sanguisorbae: [meridian distribution of property and flavor] picric acid; Cold; Nontoxic.Return liver; Lung; Kidney; Large intestine channel.[effect] cooling blood for hemostasis, heat-clearing and toxic substances removing, detumescence sore.Spit blood, spitting of blood, epistaxis, hematuria, has blood in stool, hemorrhoidal bleeding, dysentery, metrorrhagia, leucorrhea with red and white discharge, sore, carbuncle and painful swelling, eczema, pudendal pruritus, burn due to hot liquid or fire, snake bite and insect sting.[pharmacological action] 1. has astriction, can antidiarrheal and hemostasis.2. antibacterial action.3. antiinflammatory action.4. anastalsis.

Rhizoma Coptidis: effect: heat clearing and damp drying, eliminating fire and detoxication.For damp and hot feeling of fullness, vomiting acid regurgitation, dysentery, jaundice, unconsciousness due to high fever, hyperactivity of heart-fire, dysphoria and insomnia, heat in blood tells nosebleed, conjunctival congestion, and toothache, quenches one's thirst, carbuncle furuncle; External treatment eczema, eczema, auditory meatus is suppurated.It is burning hot that Rhizoma Coptidis (processed with wine) is apt to the clear part of the body cavity above the diaphragm housing the heart and lungs.For conjunctival congestion, aphtha.Prepared RHIZOMA COPTIDIS with rhizoma zingiberis recens juice clearing stomach stomach function regulating preventing or arresting vomiting.Tie mutually for cold and heat, damp and hot middle resistance, feeling of fullness is vomitted.Cornel Rhizoma Coptidis soothing liver-QI stomach function regulating preventing or arresting vomiting.For incoordination between the liver and stomach, vomiting acid regurgitation.Pharmacological action: 1, antibacterial action 2, antifungic action 3, antivirus action 4, anti-ameba effect 5, antiinflammatory, anti-CaM antibody 6., on Cardiovascular 7, refrigeration function 8, hypoglycemic activity 9, effect for reducing blood fat 10, antioxidation 11, on blood system affect 12, antiulcer action.

Cortex Phellodendri: [meridian distribution of property and flavor] is bitter, cold.Return kidney, bladder, large intestine channel.[function with cure mainly] heat clearing and damp drying, eliminating fire and detoxication, except hectic fever due to YIN-deficiency clearind deficient heat.For damp-heat dysentery, jaundice, leukorrhagia, pyretic stranguria, beriberi, flaccidity is warded off, hectic fever due to YIN-deficiency consumptive fever, night sweat, seminal emission, sore swollen toxin, eczema pruritus.Stir-baked CORTEX PHELLODENDRI with salt solution nourishing YIN to lower pathogenic fire.For hyperactivity of fire caused by deficiency of YIN, night sweat hectic fever due to YIN-deficiency.[chemical composition] Cortex Phellodendri is mainly containing berberine about 1.6%, still appoint alkali, candicine, magnoline, limonin etc. containing palmatine, phellodendrine, jateorhizine, obacunone, Caulis menispermi. root bark isolates berberine about 9%, still containing jateorhizine, phellodendrine, candicine; Cortex Phellodendri content of berberine is higher, reaches 3%; [antibacterial action] Cortex Phellodendri antibiotic effective ingredient is berberine. Cortex Phellodendri decoct or the in vitro tests of alcohol preserved material all have inhibitory action to staphylococcus aureus, Staphylococcus albus, Staphylococcus citreus, Diplococcus pneumoniae, meningococcus, Streptococcus viridans, vibrio cholera, diphtheria corynebacterium, dysentery bacterium, bacillus pyocyaneus etc., nearly unavailable to escherichia coli Radix Salviae Miltiorrhizae, Bacillus typhi.

Fructus Forsythiae: [chemical composition] fruit is containing forsythol, sterol compound, Saponin (without hemolytic) and Flavonoids, horse tongue resinol glycoside etc.Antibacterial action Fructus Forsythiae concentrated decotion has antibacterial action in vitro, can suppress Bacillus typhi, Salmonella paratyphi, escherichia coli, dysentery bacterium, diphtheria corynebacterium and vibrio cholera, staphylococcus, streptococcus etc.[function cures mainly] heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, dispelling wind and heat pathogens, has the title of " persons particularly liable to develop skin infection's panacea ".Control warm, erysipelas, macule, carbuncle and ulcer toxic swelling, scrofula, urine stranguria with urinary obstruction, clearing away heart-fire.

Olibanum: [meridian distribution of property and flavor] works hard, temperature.Enter the heart, liver, spleen channel.[pharmacological action] this product has more significant analgesic activity. and headed by Olibanum, the uterus ball of taste medicine antibacterially have stronger bacteriostasis than multiple, and effectively can kill infusorian. and regulating qi and activating blood, analgesic therapy, chases after poison.[effect] controls coagulation of QI-blood, trusted subordinate's pain, carbuncle pyogenic infections from tumour or sore, traumatic injury, dysmenorrhea, postnatal blood stasis twinge.

Folium Eucommiae: effect is classified: invigorating the liver and kidney medicine; Bone and muscle strengthening medicine; Hypotensor.In Folium Eucommiae, contained Cortex Eucommiae chlorogenic acid has antibacterial, antiinflammatory, removing toxic substances, function of gallbladder promoting, blood pressure lowering and leukocyte increasing and significantly increases gastrointestinal peristalsis and promote the pharmacological actions such as gastric secretion, has stronger inhibitory action to escherichia coli, gold-coloured staphylococci, streptococcus pneumoniae and virus; Obvious curative effects is had to acute laryngopharyngitis and dermatosis, to menorrhagia, anovulatory dysfunctional uterine hemorrhage has good haemostatic effect. and the main pharmacological of Cortex Eucommiae chlorogenic acid has: the effect such as hypotensive effect, antitumor action, the kidney invigorating, enhancing human body immunity effect, antioxidation, defying age, anti-muscle skeleton are aging, antibacterial, antiviral.

The Radix Paeoniae Alba: chemical composition: paeoniflorin, paeonol, paeoniflorin, still containing benzoic acid, volatile oil, fatty oil, resin, tannin, sugar, starch, phlegmatic temperament, protein, cupreol and triterpenes etc.Property of medicine effect: the Radix Paeoniae Alba is cool in nature, bitter in the mouth acid, is slightly cold, has the effects such as blood-supplementing blood-nourishing, suppressing liver-YANG, easing the affected liver to relieve pain, astringing YIN to stop sweating, be applicable to fever due to yin deficiency, menoxenia, the breast abdomen pain over the hypochondriac region, extremity contraction suddenly, dysentery stomachache, spontaneous sweating, metrorrhagia, the inferior disease of band.Paeoniflorin has antibacterial, antipyretic, antiinflammatory, increase coronary flow, improves the effect of myocardial nutritional flow, blood vessel dilating, antagonism acute myocardial ischemia, anticoagulant, calmness, analgesia, spasmolytic, antiulcer, adjustment blood glucose.Radix Paeoniae Alba decoct can suppress dysentery bacterium, streptococcus pneumoniae, escherichia coli, Bacillus typhi, Hemolytic streptococcus, bacillus pyocyaneus etc.

The present invention prevents and treats the Chinese medicine preparation of sheep clostridium property disease; Mainly as prevention and the treatment of sheep clostridium property disease, sheep autoimmunity and premunition can be strengthened, there is effect of anti-inflammation.

Detailed description of the invention

The present invention prevents and treats the Chinese medicine preparation of sheep clostridium property disease, it is characterized in that, is combined by the former material spice Radix Astragali, Radix Sanguisorbae, Cortex Phellodendri, Fructus Forsythiae, Olibanum, Folium Eucommiae, Rhizoma Coptidis, the Radix Paeoniae Alba.

For reaching better prevention and the effect for the treatment of sheep clostridium property disease, present invention also offers the preparation method of this Chinese medicine preparation;

Its preparation method is following steps: step one), by the raw medicinal material Radix Astragali, Radix Sanguisorbae, Cortex Phellodendri, Fructus Forsythiae, Olibanum, Folium Eucommiae, Rhizoma Coptidis, the Radix Paeoniae Alba remove impurity, eluriate rapidly with cold boiled water water, dry;

Step 2), step one) water slow fire is fried altogether for the raw medicinal material that obtains, obtains Chinese medicine preparation.

Using method: obtained Chinese medicine preparation and water 3: 5 are fed rearing sheep in pens.

Claims (1)

1. prevent and treat a Chinese medicine preparation for sheep clostridium property disease, it is characterized in that, combined by the former material spice Radix Astragali, Radix Sanguisorbae, Cortex Phellodendri, Fructus Forsythiae, Olibanum, Folium Eucommiae, Rhizoma Coptidis, the Radix Paeoniae Alba;

For reaching better prevention and the effect for the treatment of sheep clostridium property disease, present invention also offers the preparation method of this Chinese medicine preparation;

Its preparation method is following steps: step one), by the raw medicinal material Radix Astragali, Radix Sanguisorbae, Cortex Phellodendri, Fructus Forsythiae, Olibanum, Folium Eucommiae, Rhizoma Coptidis, the Radix Paeoniae Alba remove impurity, eluriate rapidly with cold boiled water water, dry;

Step 2), step one) water slow fire is fried altogether for the raw medicinal material that obtains, obtains Chinese medicine preparation.