CN104489034A - Health care biscuit with tumor preventing and treating function - Google Patents

Health care biscuit with tumor preventing and treating function Download PDF

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Publication number
CN104489034A
CN104489034A CN201410806599.8A CN201410806599A CN104489034A CN 104489034 A CN104489034 A CN 104489034A CN 201410806599 A CN201410806599 A CN 201410806599A CN 104489034 A CN104489034 A CN 104489034A
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China
Prior art keywords
different leaf
leaf anise
health care
liquid extract
parts
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CN201410806599.8A
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Chinese (zh)
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不公告发明人
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Individual
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    • AHUMAN NECESSITIES
    • A21BAKING; EDIBLE DOUGHS
    • A21DTREATMENT, e.g. PRESERVATION, OF FLOUR OR DOUGH, e.g. BY ADDITION OF MATERIALS; BAKING; BAKERY PRODUCTS; PRESERVATION THEREOF
    • A21D13/00Finished or partly finished bakery products
    • A21D13/80Pastry not otherwise provided for elsewhere, e.g. cakes, biscuits or cookies
    • AHUMAN NECESSITIES
    • A21BAKING; EDIBLE DOUGHS
    • A21DTREATMENT, e.g. PRESERVATION, OF FLOUR OR DOUGH, e.g. BY ADDITION OF MATERIALS; BAKING; BAKERY PRODUCTS; PRESERVATION THEREOF
    • A21D2/00Treatment of flour or dough by adding materials thereto before or during baking
    • A21D2/08Treatment of flour or dough by adding materials thereto before or during baking by adding organic substances
    • A21D2/36Vegetable material
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/40Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

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  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Pediatric Medicine (AREA)
  • Mycology (AREA)
  • Nutrition Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

The invention relates to health care biscuit with a tumor preventing and treating function. The health care biscuit comprises, by weight, 20 parts of pimpinella diversifolia fluid extract, 120 parts of cake flour, 10 parts of skim milk powder, 40 parts of butter and 25 parts of sugar. The pimpinella diversifolia fluid extract is made by 100 parts of pimpinella diversifolia. The health care biscuit made of wild herbs such as pimpinella diversifolia and capable of preventing and treating tumor has antibiosis function and antiviral and antitumor effects. The health care biscuit is applicable to daily eating health care of common consumers so as to prevent neoplastic diseases and is applicable to healthcare assistance of tumor patients.

Description

The health-caring biscuit of anti-curing oncoma
Technical field
The present invention relates to a kind of health-caring biscuit of anti-curing oncoma, the health-caring biscuit of the anti-curing oncoma of especially a kind of adapted Chinese medicine different leaf anise.
Background technology
Prior art does not apply the health-caring biscuit product that different leaf anise prepares anti-curing oncoma, and taste is single, shortage anti-tumor healthcare function.As being the invention of 201410334193.4 in the patent No.---a kind of celery health-care biscuit, a kind of celery health-care biscuit of this disclosure of the invention; It is made up of following raw material: celery, cucumber, ternip, sophora flower, okra, black fungus, shitosan, soybean lecithin, pagodatree flower honey, salad oil, Waxy Maize grain, black rice face, raising agent, leavening and wheat flour; This invention celery health-care biscuit, just has the general health care such as voltage stabilizing step-down, toxin expelling, weight reducing, stomach invigorating short digestion, angiocardiopathy preventing.
Summary of the invention
In order to solve prior art problem, the object of the invention is the health-caring biscuit that will provide a kind of anti-curing oncoma, be not only applicable to the daily edible health of ordinary consumer to prevent tumor disease, the treatment for the tumor patient state of an illness also plays health care booster action.
Technical scheme: a kind of health-caring biscuit of anti-curing oncoma, is made up of by weight following batching: different leaf anise liquid extract 20, low powder 120, skimmed milk power 10, butter 40, sugar 25; Described different leaf anise liquid extract makes liquid extract with different leaf anise 100 weight portion.
Preparation method is: 1, different leaf anise liquid extract and pure water are formed biscuit water for subsequent use with the ratio of 1:2; 2, butter thermoplastic, adds sugar and mixes thoroughly, beats to cream pasty state, then add biscuit water for subsequent use, low powder and skimmed milk power and mix thoroughly with egg-whisk; 3, batter being loaded piping bag squeezes on baking tray, adds a cover tinfoil.Baking box preheating 180 degree, roasting 20 minutes of middle level, turns 170 degree and bakes about 10 minutes to drying.
Experimental study: confirm that different leaf anise Chinese medicine liquid extract has obvious tumor-inhibiting action to rat liver cancer (H22) animal liver cancer model; Different leaf anise Chinese medicine liquid extract has the effect strengthening mouse cell immunity and humoral immune function, and to K562 and the A549 cell cycle, there is retardation, apoptotic effect is promoted to K562 and HepG2 cell, in protein level and mRNA level in-site are to K562 cell, short apoptogene BAX all has rise effect, to the expression of K562 cell and HepG2 cell proliferation and telomerase gene, there is remarkable inhibitory action, show that different leaf anise has obvious antitumor action thus.
Experimental technique :different leaf anise liquid extract makes different leaf anise liquid extract with different leaf anise by Chinese medicine liquid extract method for making.Set up rat liver cancer (H22) zoografting tumor model, random mouse is divided into normal group, model group, positive group, medicine is little, in, heavy dose of group and administration respectively, after experiment terminates, carry out the indexs of correlation such as tumour inhibiting rate, thymus index, spleen index, tumor tissue pathology to detect, result: the tumor growth of different leaf anise liquid extract to tumor-bearing mice has obvious inhibitory action, the tumour inhibiting rate of basic, normal, high dosage group is respectively 31.08%, 42.36% and 46.20%, presents good dose-effect relationship.Pathological observation shows, and model group growth of tumour cell is vigorous, and tumor cell necrosis in various degree then appears in each medication group, conclusion: different leaf anise liquid extract has obvious tumor-inhibiting action to rat liver cancer (H22) animal liver cancer model.
Different leaf anise is tested by " food safety evaluation on toxicology test " in " health food inspection and assessment technical specification " (2003 editions), result shows acute toxicity test its mouse oral LD50 > 20g/kg, true border is nontoxic, long_term toxcity result of study confirms: the rat feeding trial on the 30th of different leaf anise, have no experimental animal and occur poisoning symptom, gross anatomy and structure observation no abnormality seen pathological change.Rat body weight, food-intake, food utilization, blood picture, blood biochemistry are all had no significant effect.Different leaf anise high dose group dosage that is female, buck is human body RD (60mg/kg BW/d) 120 times.Confirm that Chinese herbal medicine different leaf anise long-term taking is safety non-toxic.
Clinical verification, point experimental group and control group: after experimental group adopts different leaf anise liquid extract of the present invention to treat three courses for the treatment of (90 days), compared with treating after three courses for the treatment of with control group (employing chemotherapy and radiation), the total effective rate adopting the experimental group Advanced cancers treatment of different leaf anise liquid extract treatment of the present invention is 94.2%, control group is 65.8% to the total effective rate that Advanced cancers is treated, and the total effective rate for the treatment of group is apparently higher than control group.
1, case selection: select case 240 example meeting Advanced cancers diagnostic criteria, patient is divided into two groups at random, treatment group 120 example, wherein male 66 examples (liver cancer 16 example, lung cancer 14 example, cancer of the stomach 13 example, cancer of the esophagus 9 example, brain tumor 6 example, the carcinoma of the rectum 3 example, malignant lymphoma 5 example), female 54 example (liver cancer 10 example, lung cancer 10 example, cancer of the stomach 10 example, cancer of the esophagus 8 example, brain tumor 5 example, the carcinoma of the rectum 6 example, malignant lymphoma 5 example); 22 ~ 78 years old age, 50.1 years old mean age; The course of disease 3 ~ 18 months, average 9.2 months.Control group 120 example, wherein male 64 examples (liver cancer 11 example, lung cancer 17 example, cancer of the stomach 10, the carcinoma of the rectum 8 example, carcinoma of urinary bladder 6 example, cancer of the esophagus 6 example, brain tumor 3 example, malignant lymphoma 3 example), female 56 example (liver cancer 9 example, lung cancer 10 example, cancer of the stomach 9 example, the carcinoma of the rectum 5 example, cancer of the esophagus 6 example, brain tumor 3 example, breast cancer 4 example, cervical carcinoma 3 example, oophoroma 3 example, malignant lymphoma 4 example); 25 ~ 80 years old age, 51.3 years old mean age; The course of disease 3 ~ 18 months, average 8.9 months.Two groups of qualifications and record of service are basically identical, and there was no significant difference, has comparativity.
2, treatment group patient takes different leaf anise liquid extract of the present invention, an oral 10-15 milliliter of being grown up, and 3 times on the one 30 days is a course for the treatment of; Take 90 days continuously.Control group adopts chemotherapy and radiation.
3, criterion: effective: tumour knurl body reduces more than 5%, and subjective symptoms is obviously improved, cardinal symptom disappears; Effective: tumour knurl body reduces 2 ~ 5%, and clinical symptoms are obviously improved; Improve: tumour knurl body maintains original size, clinical symptoms are improved; Invalid: tumour knurl body continuation growth and clinical symptoms are without improvement or increase the weight of.
4, result: take in treatment group of the present invention, effective: 63 examples, effective 30 examples, improve 20 examples, invalid 7 examples, total effective rate 94.2%; Effective 45 examples in control group, effective 23 examples, improve 10 examples, invalid 42 examples, total effective rate 65.0%; The total effective rate for the treatment of group is apparently higher than control group.
As optimization, the health-caring biscuit of a kind of anti-curing oncoma of the present invention, is made up of by weight following batching: different leaf anise liquid extract 20, low powder 120, skimmed milk power 10, butter 40, sugar 25; Described different leaf anise liquid extract makes liquid extract with different leaf anise 100 parts, rush 0.2-2 part, Radix Astragali 5-10 part, American Ginseng 5-10 part.
Pungent, bitter, micro-sweet, the slightly warm in nature of different leaf anise taste; Return lung; Stomach, Liver Channel.Function cures mainly: loose wind declares lung, regulating qi-flowing for relieving pain, disappear long-pending invigorating the spleen, activating blood to promote menstruation, removing dampness and detoxicating.Main flu, cough, pertussis, tuberculosis, lung carbuncle, headache, headache, bud pain, crisp hypochondriac pain, peratodynia, abdominal distention and pain, koro crymodynia, rheumatic arthritis, internal lesion caused by overexertion, bone labor, indigestion, dyspepsia, infantile malnutrition due to digestive disturbances or intestinalparasites, acute filthy disease, rush down dysentery, jaundice, malaria, irregular menstruation, dysmenorrhoea, through closing, swollen, the order screen of breast, pharynx swollen, mumps, traumatic injury, eczema, pruitus, snakeworm wound.
Rush, is slightly cold, sweet, light; The thoughts of returning home, lung, small intestine, urinary bladder channel.Effect: promoting diuresis for stranguria, clearing heart fire.
Radix Astragali taste is sweet, warm, the thoughts of returning home, lung, spleen, kidney channel; Function cures mainly: invigorating qi for strengthening superficies, diuresis, pus draining and toxin expelling, regenerating tissue to heal wond.Cure mainly palpitaition of breathing hard, burnout, weak, spontaneous perspiration, night sweat, rush down for a long time, impractical swollen, chronic nephritis, the ulcer difficulty of prolapse of the anus, the prolapse of uterus, body bursts or burst and do not hold back for a long time.The Radix Astragali has enhanced machine body immunity function, protects the liver, diuresis, anti-ageing, resisting stress, step-down and antibacterial action more widely.Jishengshenqiwan albuminuria can be eliminated, strengthen myocardial contractive power, regulate blood-sugar content.The Radix Astragali can not only coronary artery dilator, improves myocardial blood supply, improves immunologic function, and can the process of delaying cell aging.Radix Astragali instant, can decoct soup, soft extracts, infusing drugs in wine, enter dish etc.
Sweet, the micro-hardship of American Ginseng taste, cool.The thoughts of returning home, lung, kidney channel.Function cures mainly: boosting qi and nourishing yin, clearing heat and promoting fluid.For the deficiency of vital energy the moon lose, interior heat, cough breathe heavily phlegm blood, abnormal heat be tired of tired, quench one's thirst, dryness of the mouth and throat.
Advantage of the present invention is: 1, the pure and fresh glycol of taste, adds the novel taste of health-caring biscuit.Select the different leaf anise of natural Chinese medicinal herb to be raw material, use safety, utilize Chinese herbal medicine integrated control tumour, without obvious toxic-side effects; Experiment proves that different leaf anise single medicinal material liquid extract has anti-bacteria and anti-virus, cancer suppressing action; There is the immunologic function removed carcinous toxin, improve body against cancer.
2, preferably side with the removing toxic substances of different leaf anise removing damp-heat, regulating qi-flowing for relieving pain, disappear long-pending invigorating the spleen, activating blood to promote menstruation; Loose wind a surname lung; Improve effect of immunologic function, compatibility rush promoting diuresis for stranguria, clearing heart fire, Radix Astragali invigorating qi and benefiting blood, warming yang for diuresis, the effects such as removing toxic substances of calming the nerves, and American Ginseng supplement vigour, benefit strengthening spleen and lung, nourishing generate fluid, calm the nerves nourish heart, brain-tonifying effect.
3, the present invention utilizes the different leaf anise of edible wild herbs among the people to make the health-caring biscuit of control tumor disease, has anti-bacteria and anti-virus, cancer suppressing action; Be not only applicable to the daily edible health of ordinary consumer to prevent tumor disease, be applicable to the health-care assistance of tumor patient yet.
Detailed description of the invention
Embodiment 1: a kind of health-caring biscuit of anti-curing oncoma, is made up of by weight following batching: different leaf anise liquid extract 20, low powder 120, skimmed milk power 10, butter 40, sugar 25; Described different leaf anise liquid extract makes liquid extract with different leaf anise 100 weight portion.
Preparation method is: 1, different leaf anise liquid extract and pure water are formed biscuit water for subsequent use with the ratio of 1:2; 2, butter thermoplastic, adds sugar and mixes thoroughly, beats to cream pasty state, then add biscuit water for subsequent use, low powder and skimmed milk power and mix thoroughly with egg-whisk; 3, batter being loaded piping bag squeezes on baking tray, adds a cover tinfoil.Baking box preheating 180 degree, roasting 20 minutes of middle level, turns 170 degree and bakes about 10 minutes to drying.
Embodiment 2: a kind of health-caring biscuit of anti-curing oncoma, is made up of by weight following batching: different leaf anise liquid extract 20, low powder 120, skimmed milk power 10, butter 40, sugar 25; Described different leaf anise liquid extract makes liquid extract with different leaf anise 100 parts, rush 0.2-2 part, Radix Astragali 5-10 part, American Ginseng 5-10 part.
Preparation method is with embodiment 1.

Claims (2)

1. a health-caring biscuit for anti-curing oncoma, is made up of by weight following batching: different leaf anise liquid extract 20, low powder 120, skimmed milk power 10, butter 40, sugar 25; Described different leaf anise liquid extract makes liquid extract with different leaf anise 100 weight portion.
2. a health-caring biscuit for anti-curing oncoma, is made up of by weight following batching: different leaf anise liquid extract 20, low powder 120, skimmed milk power 10, butter 40, sugar 25; Described different leaf anise liquid extract makes liquid extract with different leaf anise 100 parts, rush 0.2-2 part, Radix Astragali 5-10 part, American Ginseng 5-10 part.
CN201410806599.8A 2014-12-23 2014-12-23 Health care biscuit with tumor preventing and treating function Pending CN104489034A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105211189A (en) * 2015-10-15 2016-01-06 陈业东 The biscuit that a kind of the concentrated liquid of tradition Chinese medicine is made

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1488297A (en) * 2003-07-28 2004-04-14 郑伟达 Health food for cancer patient and preparing method thereof
CN102919331A (en) * 2012-11-29 2013-02-13 胡丽萍 Health-care biscuit for preventing and treating hyperlipidemia
CN103503966A (en) * 2013-10-30 2014-01-15 杨小燕 Cake
CN103907661A (en) * 2014-04-30 2014-07-09 杨玉相 Health care biscuit capable of preventing hyperglycemia
CN103931708A (en) * 2014-03-18 2014-07-23 桂玉平 Health care biscuit for preventing and treating hyperlipidemia and production method of health care biscuit

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1488297A (en) * 2003-07-28 2004-04-14 郑伟达 Health food for cancer patient and preparing method thereof
CN102919331A (en) * 2012-11-29 2013-02-13 胡丽萍 Health-care biscuit for preventing and treating hyperlipidemia
CN103503966A (en) * 2013-10-30 2014-01-15 杨小燕 Cake
CN103931708A (en) * 2014-03-18 2014-07-23 桂玉平 Health care biscuit for preventing and treating hyperlipidemia and production method of health care biscuit
CN103907661A (en) * 2014-04-30 2014-07-09 杨玉相 Health care biscuit capable of preventing hyperglycemia

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Title
徐晓卫: "浙江产异叶茴芹叶挥发油化学成分研究", 《中国药业》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105211189A (en) * 2015-10-15 2016-01-06 陈业东 The biscuit that a kind of the concentrated liquid of tradition Chinese medicine is made

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