CN104430373A - Fungicidal composition - Google Patents
Fungicidal composition Download PDFInfo
- Publication number
- CN104430373A CN104430373A CN201410743257.6A CN201410743257A CN104430373A CN 104430373 A CN104430373 A CN 104430373A CN 201410743257 A CN201410743257 A CN 201410743257A CN 104430373 A CN104430373 A CN 104430373A
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- China
- Prior art keywords
- cyprodinil
- acid amides
- ether acid
- chlorobenzene ether
- cucumber
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- 0 CC1(C(Nc(cccc2)c2Oc(c(Cl)c2)cc*2Cl)=O)C(C(F)F)=NC(C)=CC1 Chemical compound CC1(C(Nc(cccc2)c2Oc(c(Cl)c2)cc*2Cl)=O)C(C(F)F)=NC(C)=CC1 0.000 description 1
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- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention belongs to the technical field of pesticides and relates to a fungicidal composition. The fungicidal composition is characterized in that active components comprise chlorobenzene ether amide and cyprodinil. The composition can be prepared into a suspending agent and water dispersible granules; and the fungicidal composition has a remarkable synergistic effect and has no phytotoxicity to crops.
Description
Technical field
The invention belongs to technical field of pesticide, contain the bactericidal composition with synergistic effect of chlorobenzene ether acid amides and cyprodinil specifically.
Background technology
Chlorobenzene ether acid amides is Central China Normal University's pyrazol acid amide compounds newly developed, has good control efficiency, have good preventive effect simultaneously to the banded sclerotial blight of paddy rice and wheat to the disease such as epidemic disease, downy mildew, tikka of the plants such as cucumber, tomato, potato.Field trial shows do not have cross resistance with existing bactericide.Structural formula is as follows:
Cyprodinil (Cyprodynil) has protection, treatment, blade penetrate and root systemic activity.Be mainly used in preventing and treating gray mold, powdery mildew, scab, leaf spot, to be full of rot and wheat eyeprint sick etc.To crop safety, without poisoning.
Powdery mildew of cucumber is one of Common Diseases in cucumber cultivation.Due in recent years, powdery mildew produces certain pesticide resistance, and all can fall ill throughout the year, brings certain difficulty to control.The general time underproduction is about 10%, and the popular time underproduction is about 20% ~ 40%.
Summary of the invention
The object of this invention is to provide and a kind ofly there is synergistic effect and the bactericidal composition of safety and environmental protection, for preventing and treating powdery mildew of cucumber, compared with existing pesticide control, realizing improving drug effect, decreasing pollution, the object that reduces costs.Be specifically related to the bactericidal composition of chlorobenzene ether acid amides and cyprodinil.
Utilize above-mentioned bactericidal composition, be equipped with the known auxiliary agent of those skilled in that art, make formulation of the present invention with the known method of those skilled in that art, comprise suspending agent and water dispersible granules.
In above-mentioned bactericidal composition, the proportion of chlorobenzene ether acid amides and cyprodinil is 1:50-50:1.
Above-mentioned bactericidal composition has obvious synergistic effect, formulation environmental protection, can be good at playing drug effect, environmentally friendly.
Embodiment
For determining chlorobenzene ether acid amides and the composite synergistic effect of cyprodinil two kinds of active ingredients, first applicant uses these two kinds of compositions to carry out indoor biometrics test, after the action character analyzing two kinds of active ingredients, the raw object surveyed is decided to be powdery mildew of cucumber by us, the pathogen of this disease is fungi, belongs to Ascomycotina gang pyrenomycetes Erysiphales Erysiphaceae Sphaerotheca.
The test method of indoor biometrics: reference standard NY/T1156.7-2006, adopts growth rate method to measure medicament to the inhibitory action of powdery mildew of cucumber pathogen mycelial growth.On the basis of preliminary experiment, from each medicament, design 5 concentration within the scope of 10%-90% are reached to germ mycelial growth inhibition rate, it is for subsequent use by the 95% former medicine of chlorobenzene ether acid amides and the former medicine of 95% cyprodinil with acetone to be first that solvent is made into the liquid of series concentration, then liquid is joined in 1% ratio in the PDA medium melting also cool to room temperature, after fully shaking up, pour in the culture dish (Φ 90mm) of sterilizing and make band medicine flat board, often process and repeat, to add the process of sterile water for blank for four times; With card punch (Φ 5mm) the picking cucumber powdery mildew's pathogen bacterium cake of sterilizing, mycelia faces down aseptic inoculation in the central authorities of band medicine flat board, be inverted in the interior cultivation of constant incubator of 27 DEG C, adopt right-angled intersection method to measure colony diameter after cultivating 6d, calculate the EC of each medicament to pathogen
50, and calculate toxicity index according to the following equation, compare virulence and the bacteriostasis of different agents.Former medicine used is tested in above-mentioned raw test and reagent is all bought from other producers.
The co-toxicity coefficient method representation that the co-toxicity of mixture preparation adopts Sun Yun abundant:
The theoretical toxicity index TTI=∑ of mixture preparation (percentage of this pharmaceutically active ingredient of the toxicity index ATI of certain medicine × in mixture).
Be synergistic effect when co-toxicity coefficient CTC is greater than 120, being antagonism when being less than 80, is addition time between 80-120.
Indoor biometrics experimental data sees the following form:
Table 1 chlorobenzene ether acid amides, cyprodinil and different ratio thereof are to the measurement result of powdery mildew of cucumber pathogen co-toxicity coefficient
Analyze above-mentioned data can obviously find out, when chlorobenzene ether acid amides and cyprodinil are composite in varing proportions, the co-toxicity coefficient (CTC) of formula is all greater than 120, the prevention and control capability of powdery mildew of cucumber is had to the synergistic effect of different proportion.
Tested by indoor biometrics, determine chlorobenzene ether acid amides and cyprodinil two kinds of active ingredients composite after, can have good synergistic effect, below by way of instantiation in order to further describe the present invention, but the present invention is absolutely not only only limitted to these embodiments following.In formula, percentage is all weight percentage, and the former medicine used and auxiliary agent are other producers and buy.
Formulation examples is as follows:
Example one, 25.5% chlorobenzene ether acid amides cyprodinil suspending agent
Example two, 51% chlorobenzene ether acid amides cyprodinil water dispersible granule
Example three, 21% chlorobenzene ether acid amides cyprodinil suspending agent
Example four, 12.6% chlorobenzene ether acid amides cyprodinil water dispersible granule
Example five, 22% chlorobenzene ether acid amides cyprodinil water dispersible granule
Example six, 33% chlorobenzene ether acid amides cyprodinil water dispersible granule
Example seven, 24% chlorobenzene ether acid amides cyprodinil water dispersible granule
Example eight, 30% chlorobenzene ether acid amides cyprodinil suspending agent
Example nine, 26% chlorobenzene ether acid amides cyprodinil water dispersible granule
Select above example to carry out preventing and treating the field trial of powdery mildew of cucumber, determine to fill a prescription and prevent and treat the effect of powdery mildew of cucumber, simultaneously with the Contrast on effect of chlorobenzene ether acid amides and cyprodinil single dose, the control efficiency of the checking embodiment of the present invention.Concrete test method is with reference to GB/T17980.30-2000.Test site is area, Xianyang, Shanxi province, and the time is on April 26th, 2014, and test each process four repetition, community randomized arrangement, each plot area is 16m
2, adopt back-pack electric compression sprayer, dispenser was sunny calm for the same day, and the planting habit of planting habit all with local of all communities is identical, records the synoptic data on the dispenser same day and a week thereafter, specific as follows:
Table 2 duration of test meteorological data
Investigation method is: every community gets 4 points at random, and whole blades of often some investigation 2 strains, every sheet leaf accounts for the percentage classification record of leaf area by scab.
The grade scale of disease index:
0 grade: without scab;
1 grade: lesion area accounts for less than 5% of whole leaf area;
3 grades: lesion area accounts for 6% ~ 10% of whole leaf area;
5 grades: lesion area accounts for 11% ~ 20% of whole leaf area;
7 grades: lesion area accounts for 21% ~ 40% of whole leaf area;
9 grades: lesion area accounts for more than 40% of whole leaf area.
Table 3 26% chlorobenzene ether acid amides cyprodinil water dispersible granule and different agents are to the preventive effect of powdery mildew of cucumber
As can be seen from above-mentioned data, chlorobenzene ether acid amides and cyprodinil complex preparation after medicine 7 days preventive effects all more than 70%, and 24% chlorobenzene ether amide suspending agents, 7 days preventive effects after medicine are 41.13%, the preventive effect of 50% cyprodinil water dispersible granule is 38.31%, compare two kinds of single doses, complex preparation has good synergistic effect.After medicine 21 days, all complex preparations all exceeded 72% to the preventive effect of powdery mildew of cucumber, and both are environmental protection formulation at composite formulation, extend the lasting period, more lasting to the control efficiency of powdery mildew of cucumber, environmentally safe close friend, reduce peasant's amount of labour, have good economic benefit.
Claims (2)
1. a bactericidal composition, is characterized in that: active component is made up of chlorobenzene ether acid amides and cyprodinil, and the weight ratio of described chlorobenzene ether acid amides and cyprodinil is 1:50 ~ 50:1.
2. composition according to claim 1, is characterized in that: make suspending agent, water dispersible granules by active component and auxiliary material.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410743257.6A CN104430373A (en) | 2014-12-05 | 2014-12-05 | Fungicidal composition |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410743257.6A CN104430373A (en) | 2014-12-05 | 2014-12-05 | Fungicidal composition |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN104430373A true CN104430373A (en) | 2015-03-25 |
Family
ID=52877729
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410743257.6A Pending CN104430373A (en) | 2014-12-05 | 2014-12-05 | Fungicidal composition |
Country Status (1)
| Country | Link |
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| CN (1) | CN104430373A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110214785A (en) * | 2018-03-01 | 2019-09-10 | 燕化永乐（乐亭）生物科技有限公司 | A kind of composite bactericide |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1226244A (en) * | 1996-07-24 | 1999-08-18 | 拜尔公司 | Carbanilides used as pesticides |
| CN101056858A (en) * | 2004-09-06 | 2007-10-17 | 巴斯福股份公司 | (hetero)cyclyl(thio) carboxylic acid anilides for controlling pathogenic fungi |
| CN103391925A (en) * | 2010-11-15 | 2013-11-13 | 拜耳知识产权有限责任公司 | 5-halogenopyrazolecarboxamides |
-
2014
- 2014-12-05 CN CN201410743257.6A patent/CN104430373A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1226244A (en) * | 1996-07-24 | 1999-08-18 | 拜尔公司 | Carbanilides used as pesticides |
| CN101056858A (en) * | 2004-09-06 | 2007-10-17 | 巴斯福股份公司 | (hetero)cyclyl(thio) carboxylic acid anilides for controlling pathogenic fungi |
| CN103391925A (en) * | 2010-11-15 | 2013-11-13 | 拜耳知识产权有限责任公司 | 5-halogenopyrazolecarboxamides |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110214785A (en) * | 2018-03-01 | 2019-09-10 | 燕化永乐（乐亭）生物科技有限公司 | A kind of composite bactericide |
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Application publication date: 20150325 |