CN104383153A - Traditional Chinese medicine for treating biliary cirrhosis and preparation method thereof - Google Patents
Traditional Chinese medicine for treating biliary cirrhosis and preparation method thereof Download PDFInfo
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- CN104383153A CN104383153A CN201410657105.4A CN201410657105A CN104383153A CN 104383153 A CN104383153 A CN 104383153A CN 201410657105 A CN201410657105 A CN 201410657105A CN 104383153 A CN104383153 A CN 104383153A
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- melanteritum
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- 239000003814 drug Substances 0.000 title claims abstract description 29
- 208000008439 Biliary Liver Cirrhosis Diseases 0.000 title claims abstract description 18
- 206010004659 Biliary cirrhosis Diseases 0.000 title claims abstract description 14
- 238000002360 preparation method Methods 0.000 title claims description 6
- 241001571764 Lysimachia christinae Species 0.000 claims abstract description 15
- 239000003610 charcoal Substances 0.000 claims description 25
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 19
- 238000001914 filtration Methods 0.000 claims description 15
- 239000010231 banlangen Substances 0.000 claims description 14
- VYQNWZOUAUKGHI-UHFFFAOYSA-N monobenzone Chemical compound C1=CC(O)=CC=C1OCC1=CC=CC=C1 VYQNWZOUAUKGHI-UHFFFAOYSA-N 0.000 claims description 14
- 241000209094 Oryza Species 0.000 claims description 10
- 235000007164 Oryza sativa Nutrition 0.000 claims description 10
- 235000009566 rice Nutrition 0.000 claims description 10
- 210000000582 semen Anatomy 0.000 claims description 10
- 235000021419 vinegar Nutrition 0.000 claims description 10
- 239000000052 vinegar Substances 0.000 claims description 10
- 238000001035 drying Methods 0.000 claims description 7
- 238000009835 boiling Methods 0.000 claims description 6
- 239000000706 filtrate Substances 0.000 claims description 6
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 claims description 5
- 238000001816 cooling Methods 0.000 claims description 5
- 229910052802 copper Inorganic materials 0.000 claims description 5
- 239000010949 copper Substances 0.000 claims description 5
- 238000010438 heat treatment Methods 0.000 claims description 5
- 238000000034 method Methods 0.000 claims description 5
- 239000000203 mixture Substances 0.000 claims description 5
- 230000000694 effects Effects 0.000 abstract description 5
- 208000033222 Biliary cirrhosis primary Diseases 0.000 abstract description 4
- 208000012654 Primary biliary cholangitis Diseases 0.000 abstract description 4
- 206010008609 Cholangitis sclerosing Diseases 0.000 abstract description 2
- 206010023129 Jaundice cholestatic Diseases 0.000 abstract description 2
- 201000005267 Obstructive Jaundice Diseases 0.000 abstract description 2
- 208000010157 sclerosing cholangitis Diseases 0.000 abstract description 2
- 239000000463 material Substances 0.000 abstract 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- 241000037740 Coptis chinensis Species 0.000 abstract 1
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 abstract 1
- 244000303040 Glycyrrhiza glabra Species 0.000 abstract 1
- 241000334160 Isatis Species 0.000 abstract 1
- 244000170916 Paeonia officinalis Species 0.000 abstract 1
- 235000006484 Paeonia officinalis Nutrition 0.000 abstract 1
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- 235000017089 Scutellaria baicalensis Nutrition 0.000 abstract 1
- 235000015506 Solanum lyratum Nutrition 0.000 abstract 1
- 241000585552 Solanum lyratum Species 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- LPLVUJXQOOQHMX-QWBHMCJMSA-N glycyrrhizinic acid Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@@H]1O[C@@H]1C([C@H]2[C@]([C@@H]3[C@@]([C@@]4(CC[C@@]5(C)CC[C@@](C)(C[C@H]5C4=CC3=O)C(O)=O)C)(C)CC2)(C)CC1)(C)C)C(O)=O)[C@@H]1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O LPLVUJXQOOQHMX-QWBHMCJMSA-N 0.000 abstract 1
- SURQXAFEQWPFPV-UHFFFAOYSA-L iron(2+) sulfate heptahydrate Chemical compound O.O.O.O.O.O.O.[Fe+2].[O-]S([O-])(=O)=O SURQXAFEQWPFPV-UHFFFAOYSA-L 0.000 abstract 1
- 235000011477 liquorice Nutrition 0.000 abstract 1
- 229910052603 melanterite Inorganic materials 0.000 abstract 1
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- 206010041660 Splenomegaly Diseases 0.000 description 1
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Classifications
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Abstract
The invention discloses a traditional Chinese medicine for treating biliary cirrhosis. The traditional Chinese medicine consists of the following components in parts by weight: 29-31 parts of Radix Puerariae, 9-10.5 parts of scutellaria baicalensis, 5-7 parts of coptis chinensis, 13-16 parts of isatis root, 9-11 parts of rhizoma alismatis, 9-11 parts of spina gleditsiae, 28-32 parts of white paeony root, 9.5-10.5 parts of liquorice, 29-31 parts of lysimachia christinae, 28-32 parts of solanum lyratum and 14-16 parts of carbon melanterite. The traditional Chinese medicine has good curative effects for treating primary biliary cirrhosis, sclerosing cholangitis and obstructive jaundice. The course of treatment is shortened, common medicinal materials are taken as main medicinal materials, and the pharmaceutical cost is reduced.
Description
Technical field
The invention belongs to technical field of Chinese medicines, specifically a kind of Chinese medicine for the treatment of biliary cirrhosis and preparation method thereof.
Background technology
Biliary cirrhosis system is detained due to long-term hepatic bile, or caused by extrahepatic biliary passages more hinders.The former is called primary biliary cirrhosis, and the latter is called that secondary biliary hardens.This disease 90% betides women, is more common in the women of 40 ~ 60 years old especially, man: female is 1: 8.The pruritus that early symptom only has slightly tired and interval to occur, 1/2 has hepatomegaly, and 1/4 has splenomegaly, and it is often that unique positive finds that serum alkaline phosphatase and γ-GT raise.Whole latter stage shows as liver failure, and cirso-breaks, hepatic encephalopathy, ascites, edema companion deep icterus.
In prior art, the Chinese medicine of common treatment biliary cirrhosis is varied, major part Therapeutic Method does not all distinguish the essential attribute of medicine well, people can think the medical material that price is high, therapeutic effect is better, then Chinese crude drug mixing used is decocted, but the property of medicine of its raw material of Chinese medicine does not discharge well.In addition, the course for the treatment of of existing method treatment biliary cirrhosis at least needs one and a half months, and the cycle is long.Now in order to overcome the defect of prior art, provide a kind of new technical scheme.
Summary of the invention
The object of the invention is to overcome prior art defect, a kind of Chinese medicine for the treatment of biliary cirrhosis and preparation method thereof is provided.
Object of the present invention can be achieved through the following technical solutions:
Treat a Chinese medicine for biliary cirrhosis, this Chinese medicine is made up of the component of following weight portion: Radix Puerariae 29-31 part, Radix Scutellariae 9-10.5 part, Rhizoma Coptidis 5-7 part, Radix Isatidis 13-16 part, Rhizoma Alismatis 9-11 part, sky fourth 9-11 part, Radix Paeoniae Alba 28-32 part, Radix Glycyrrhizae 9.5-10.5 part, Lysimachia christinae Hance 29-31 part, Herba Solani Lyrati 28-32 part, Melanteritum charcoal 14-16 part;
Preferably, this Chinese medicine is made up of the component of following weight portion: Radix Puerariae 30 parts, Radix Scutellariae 10 parts, Rhizoma Coptidis 6 parts, Radix Isatidis 15 parts, Rhizoma Alismatis 10 part, day fourth 10 parts, the Radix Paeoniae Alba 30 parts, 10 parts, Radix Glycyrrhizae, Lysimachia christinae Hance 30 parts, Herba Solani Lyrati 30 parts, Melanteritum charcoal 15 parts.
Preferably, described Melanteritum charcoal is 1: 2: 1 by weight ratio Melanteritum, rice vinegar and Semen setariae form.
The preparation method of described Melanteritum charcoal is: Melanteritum, rice vinegar are placed in heating in copper pot and dissolve, adds Semen setariae and mix taking-up thoroughly, dry; After drying, charcoal forged into by little fire, spreads cooling out, pulverize with byssus.
Preferably, to pulverize described in 80 mesh sieves.
Present invention also offers a kind of method preparing this Chinese medicine, comprise the following steps:
By Radix Puerariae, Radix Scutellariae, Rhizoma Coptidis, Radix Isatidis, Rhizoma Alismatis, sky fourth, the Radix Paeoniae Alba, Radix Glycyrrhizae, Lysimachia christinae Hance, Herba Solani Lyrati cold water soak 30min;
Big fire is heated to boiling, and 20min endured by little fire, filters head is decocted;
Filtering residue adds cold water and heavily decocts 20min, and after filtering, filtrate is decocted with head and mixed, and forms mixed liquor, then mixed liquor is evenly divided into three parts;
Melanteritum charcoal equivalent being added divides equally in rear mixed liquor, early, middle and late oral.
The amount of cold water described in above-mentioned steps of the present invention is for covering medical material 1 cun.
Radix Puerariae: having induces sweat brings down a fever, the function of promoting the production of body fluid to quench thirst, antidiarrheal, and the symptom such as dizziness, headache, tinnitus of hypertensive patient can be improved.
Radix Scutellariae: bitter, cold in nature, has heat clearing and damp drying, eliminating fire and detoxication, hemostasis, the effect such as antiabortive.
Rhizoma Coptidis: heat clearing and damp drying, eliminating fire and detoxication.
Radix Isatidis: the effect with heat-clearing and toxic substances removing, preventing cold, sore-throat relieving, bitter in the mouth.
Rhizoma Alismatis: diuretic, eliminating dampness by diuresis, expels the heat-evil.
It fourth: expelling phlegm for arresting cough, logical closing of having one's ideas straightened out.
The Radix Paeoniae Alba: there is the effects such as blood-supplementing blood-nourishing, suppressing liver-YANG, easing the affected liver to relieve pain, astringing YIN to stop sweating.
Radix Glycyrrhizae: heat-clearing and toxic substances removing, expelling phlegm for arresting cough etc.
Lysimachia christinae Hance: heat-clearing and toxic substances removing, diuresis and expelling stone.
Herba Solani Lyrati: there is clearing away heat-damp and promoting diuresis, removing toxic substances and promoting subsidence of swelling, anticancer effect.
Beneficial effect of the present invention: the present invention treats primary biliary cirrhosis, sclerosing cholangitis, obstructive jaundice have good curative effect; Present invention reduces and treat the course for the treatment of, medical material, also based on common medical material, decreases pharmacy cost.
Detailed description of the invention
For the ease of it will be appreciated by those skilled in the art that the present invention is further illustrated below in conjunction with specific embodiment.
Embodiment 1
Get the raw materials ready: Radix Puerariae 30g, Radix Scutellariae 10g, Rhizoma Coptidis 6g, Radix Isatidis 15g, Rhizoma Alismatis 10g, sky fourth 10g, Radix Paeoniae Alba 30g, Radix Glycyrrhizae 10g, Lysimachia christinae Hance 30g, Herba Solani Lyrati 30g;
Melanteritum 5g, rice vinegar 10g, Semen setariae 5g;
Melanteritum, rice vinegar are placed in heating in copper pot and dissolve, adds Semen setariae and mix taking-up thoroughly, dry; After drying, charcoal forged into by little fire, spreads cooling out with byssus, after pulverizing, crosses 80 mesh sieves, makes Melanteritum charcoal, get Melanteritum charcoal 15g, stand-by.
Prepare Chinese medicine: by Radix Puerariae, Radix Scutellariae, Rhizoma Coptidis, Radix Isatidis, Rhizoma Alismatis, sky fourth, the Radix Paeoniae Alba, Radix Glycyrrhizae, Lysimachia christinae Hance, Herba Solani Lyrati cold water soak 30min, the amount of cold water is for covering medical material 1 cun (about 3.33cm); Big fire is heated to boiling, and 20min endured by little fire, and filter head is decocted, head is decocted and poured out, surplus filtering residue, stand-by;
Filtering residue is added again cold water and heavily decoct 20min, the amount of cold water is for covering medical material 1 cun (about 3.33cm), and after filtering, filtrate is decocted with head and mixed, and forms mixed liquor, then mixed liquor is evenly divided into three parts; Melanteritum charcoal equivalent (5g, 5g, 5g) being added divides equally in rear mixed liquor, early, middle and late oral.
Example 1
Money, female, 52 years old, with in July, 1993 because there is malaise without obvious inducement, abnormal liver function, at county hospital hospitalization, get rid of viral hepatitis, fall enzyme treatment through hepatoprotective, improvement is left hospital, liver function still recurrent fluctuations after leaving hospital, companion's malaise, the vexed pain of rib, poor appetite.Occur over the nearly moon that skin is yellow, itch, yellow urine, stool complexion changed is shallow, goes to provincial hospital and intends examining into primary biliary cirrhosis.
The same day, lab testing liver function was: B ultrasonic shows: hepatomegaly, has no occupying lesion, and extrahepatic duct is without exception, and biliary tract wall is slightly crude, has no calculus.
Differential diagnosis in tcm: complexion cadmium yellow, weak, poor appetite, time have feel sick without vomiting, skin pruritus, urine buff, large loose stool, light red tongue, thin white fur of tongue is greasy, and tongue postmedian is slightly yellow, stringy and rolling pulse.
Tcm diagnosis: jaundice, YANG jaundice, weight in wet base is in pattern of fever.
The rule for the treatment of: clearing away heat-damp and promoting diuresis, detoxifying and descending turbid.
Chinese medicine is obtained, under early, middle and late 3 clothes by method described in embodiment 1.Weak after one week, body is stranded, and poor appetite is all got better and turned, and after continuing to take 10 days, jaundice goes down, and urine complexion changed is light, looks into liver function and takes a turn for the better, the basic rehabilitation of the state of an illness after 4 weeks after 2 weeks.
Embodiment 2
Get the raw materials ready: Radix Puerariae 31g, Radix Scutellariae 9g, Rhizoma Coptidis 5g, Radix Isatidis 16g, Rhizoma Alismatis 16g, sky fourth 11g, Radix Paeoniae Alba 28g, Radix Glycyrrhizae 10.5g, Lysimachia christinae Hance 31g, Herba Solani Lyrati 28g;
Melanteritum 5g, rice vinegar 10g, Semen setariae 5g;
Melanteritum, rice vinegar are placed in heating in copper pot and dissolve, adds Semen setariae and mix taking-up thoroughly, dry; After drying, charcoal forged into by little fire, spreads cooling out with byssus, after pulverizing, crosses 80 mesh sieves, makes Melanteritum charcoal, get Melanteritum charcoal 16g, stand-by.
Prepare Chinese medicine: by Radix Puerariae, Radix Scutellariae, Rhizoma Coptidis, Radix Isatidis, Rhizoma Alismatis, sky fourth, the Radix Paeoniae Alba, Radix Glycyrrhizae, Lysimachia christinae Hance, Herba Solani Lyrati cold water soak 30min, the amount of cold water is for covering medical material 1 cun (about 3.33cm); Big fire is heated to boiling, and 20min endured by little fire, and filter head is decocted, head is decocted and poured out, surplus filtering residue, stand-by;
Filtering residue is added again cold water and heavily decoct 20min, the amount of cold water is for covering medical material 1 cun (about 3.33cm), and after filtering, filtrate is decocted with head and mixed, and forms mixed liquor, then mixed liquor is evenly divided into three parts; Melanteritum charcoal equivalent being added divides equally in rear mixed liquor, early, middle and late oral.
Embodiment 3
Get the raw materials ready: Radix Puerariae 29g, Radix Scutellariae 10.5g, Rhizoma Coptidis 7g, Radix Isatidis 13g, Rhizoma Alismatis 11g, sky fourth 9g, Radix Paeoniae Alba 32g, Radix Glycyrrhizae 9.5g, Lysimachia christinae Hance 29g, Herba Solani Lyrati 32g;
Melanteritum 5g, rice vinegar 10g, Semen setariae 5g;
Melanteritum, rice vinegar are placed in heating in copper pot and dissolve, adds Semen setariae and mix taking-up thoroughly, dry; After drying, charcoal forged into by little fire, spreads cooling out with byssus, after pulverizing, crosses 80 mesh sieves, makes Melanteritum charcoal, get Melanteritum charcoal 14g, stand-by.
Prepare Chinese medicine: by Radix Puerariae, Radix Scutellariae, Rhizoma Coptidis, Radix Isatidis, Rhizoma Alismatis, sky fourth, the Radix Paeoniae Alba, Radix Glycyrrhizae, Lysimachia christinae Hance, Herba Solani Lyrati cold water soak 30min, the amount of cold water is for covering medical material 1 cun (about 3.33cm); Big fire is heated to boiling, and 20min endured by little fire, and filter head is decocted, head is decocted and poured out, surplus filtering residue, stand-by;
Filtering residue is added again cold water and heavily decoct 20min, the amount of cold water is for covering medical material 1 cun (about 3.33cm), and after filtering, filtrate is decocted with head and mixed, and forms mixed liquor, then mixed liquor is evenly divided into three parts; Melanteritum charcoal equivalent being added divides equally in rear mixed liquor, early, middle and late oral.
Above content is only citing made for the present invention and explanation; affiliated those skilled in the art make various amendment to described specific embodiment or supplement or adopt similar mode to substitute; only otherwise depart from invention or surmount this scope as defined in the claims, protection scope of the present invention all should be belonged to.
Claims (6)
1. treat the Chinese medicine of biliary cirrhosis for one kind, it is characterized in that, this Chinese medicine is made up of the component of following weight portion: Radix Puerariae 29-31 part, Radix Scutellariae 9-10.5 part, Rhizoma Coptidis 5-7 part, Radix Isatidis 13-16 part, Rhizoma Alismatis 9-11 part, sky fourth 9-11 part, Radix Paeoniae Alba 28-32 part, Radix Glycyrrhizae 9.5-10.5 part, Lysimachia christinae Hance 29-31 part, Herba Solani Lyrati 28-32 part, Melanteritum charcoal 14-16 part;
This Chinese medicine is prepared by following methods:
By Radix Puerariae, Radix Scutellariae, Rhizoma Coptidis, Radix Isatidis, Rhizoma Alismatis, sky fourth, the Radix Paeoniae Alba, Radix Glycyrrhizae, Lysimachia christinae Hance, Herba Solani Lyrati cold water soak 30min;
Big fire is heated to boiling, and 20min endured by little fire, filters head is decocted;
Filtering residue adds cold water and heavily decocts 20min, and after filtering, filtrate is decocted with head and mixed, and forms mixed liquor, then mixed liquor is evenly divided into three parts;
Melanteritum charcoal equivalent being added divides equally in rear mixed liquor, early, middle and late oral.
2. the Chinese medicine for the treatment of biliary cirrhosis according to claim 1, it is characterized in that, this Chinese medicine is made up of the component of following weight portion: Radix Puerariae 30 parts, Radix Scutellariae 10 parts, Rhizoma Coptidis 6 parts, Radix Isatidis 15 parts, Rhizoma Alismatis 10 part, day fourth 10 parts, the Radix Paeoniae Alba 30 parts, 10 parts, Radix Glycyrrhizae, Lysimachia christinae Hance 30 parts, from English 30 parts, Melanteritum charcoal 15 parts.
3. the Chinese medicine for the treatment of biliary cirrhosis according to claim 1 and 2, is characterized in that, Melanteritum, rice vinegar and Semen setariae that described Melanteritum charcoal is 1: 2: 1 by weight ratio form.
4. the Chinese medicine for the treatment of biliary cirrhosis according to claim 3, is characterized in that, the preparation method of described Melanteritum charcoal is: Melanteritum, rice vinegar are placed in heating in copper pot and dissolve, adds Semen setariae and mix taking-up thoroughly, dry; After drying, charcoal forged into by little fire, spreads cooling out, pulverize with byssus.
5. the Chinese medicine for the treatment of biliary cirrhosis according to claim 4, is characterized in that, described in pulverize 80 mesh sieves.
6. prepare a method for Chinese medicine as claimed in claim 1, it is characterized in that, comprise the following steps:
By Radix Puerariae, Radix Scutellariae, Rhizoma Coptidis, Radix Isatidis, Rhizoma Alismatis, sky fourth, the Radix Paeoniae Alba, Radix Glycyrrhizae, Lysimachia christinae Hance, Herba Solani Lyrati cold water soak 30min;
Big fire is heated to boiling, and 20min endured by little fire, filters head is decocted;
Filtering residue adds cold water and heavily decocts 20min, and after filtering, filtrate is decocted with head and mixed, and forms mixed liquor, then mixed liquor is evenly divided into three parts;
Melanteritum charcoal equivalent being added divides equally in rear mixed liquor, early, middle and late oral.
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103845429A (en) * | 2014-03-02 | 2014-06-11 | 马青 | Traditional Chinese medicine for treating chronic hepatitis |
| CN104013685A (en) * | 2014-06-28 | 2014-09-03 | 蚌埠明日欣医药有限公司 | Traditional Chinese medicine prescription for treating liver and gallbladder damp-heat type jaundice |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103845429A (en) * | 2014-03-02 | 2014-06-11 | 马青 | Traditional Chinese medicine for treating chronic hepatitis |
| CN104013685A (en) * | 2014-06-28 | 2014-09-03 | 蚌埠明日欣医药有限公司 | Traditional Chinese medicine prescription for treating liver and gallbladder damp-heat type jaundice |
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