CN104336078A - Chlorine-containing Chinese herbal medicine air disinfectant, and preparation method and application thereof - Google Patents
Chlorine-containing Chinese herbal medicine air disinfectant, and preparation method and application thereof Download PDFInfo
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Abstract
The invention provides a chlorine-containing Chinese herbal medicine air disinfectant comprising the following components, by weight: 30-70 parts of a stable chlorine-containing granule system A, 10-50 parts of an activated granule system B, and 20-50 parts of a Chinese herbal medicine granule system C. The invention also provides a preparation method of the chlorine-containing Chinese herbal medicine air disinfectant. The chlorine-containing Chinese herbal medicine air disinfectant has the advantages of simple preparation process and easy-to-obtain raw material components. Sterilizing and disinfecting effects of Chinese herbal medicines and chlorine dioxide are integrated in the disinfectant. The disinfectant also has air-clarifying, soothing and refreshing effects. With the disinfectant, human health can be protected, and a safe and comfortable environment can be provided. The disinfectant can be used in air refreshing, air clarification and disinfection of office environments, homes and public places. The disinfectant has good application value and market prospect.
Description
Technical field
The present invention relates to technical field of air purification, particularly relate to a kind of chloride formula Chinese herbal medicine air disinfectant and its preparation method and application.
Background technology
Due to the germ being filled with various infectious pathogenic microorganisms and easily contaminate in our living environment, therefore, Antiepidemic sterilizing kills various infectious pathogenic microorganisms and bacterium, preventing disease infection, ensures healthy important measures.
The Chinese herbal medicine resource of China enriches, and has the Clinical Experience of thousands of years, and in conjunction with the research and development of modern science and technology, Chinese herbal medicine has very large advantage and potential in research and development that are antibacterial, anti-virus aspect.
Volatile Oil of Medicinal Herbs, has another name called essential oil, is the general name of the volatility oily composition not miscible with water that a class can obtain with steam distillation.Volatile Oil of Medicinal Herbs has anti-inflammatory, antiallergy, antimicrobial, anti-sudden change and anticancer, anthelmintic action, enzyme inhibition, effect etc. to central nervous system and respiratory system.
Chlorine dioxide is the strong fungicide of a kind of safe, efficient, the wide spectrum that World Health Organization confirms, its sterilizing ability is 5 times of chlorine, has good killing and inhibition for bacterium, virus.Particularly the Chlorine dioxide production of slowly-releasing slowly can discharge the chlorine dioxide of low concentration in a long time constantly, effectively kill the pathogenic microorganism in air, prevent indoor article from going mouldy in a humid environment, sterilization and the double effect of sterilization are carried out to air.
There is multiple chlorinated products in the market, in the stability that most products focuses on chlorine dioxide and slow release method, some shortcomings of existence in various degree: (1) only focuses on the disinfection of chlorine dioxide, have ignored the protection to health; (2) chlorine dioxide has special pungent odor, is not easily accepted.
Therefore, a kind of can slow releasing chlorine dioxide, sterilizing is carried out to environment, fresh air of simultaneously holding concurrently, soothe the spirit, cool and refreshing air in one, the air sanitizer of protection health, has wide using value and market prospects.
Summary of the invention
For solving the problem; the invention provides a kind of chloride formula Chinese herbal medicine air disinfectant; the mediation effect of Chinese herbal medicine uniqueness effectively combines with the bactericidal action of chloride particle by described air sanitizer; energy slow releasing chlorine dioxide; the sterilizing of double Chinese herbal medicine and chlorine dioxide is integrated; again can fresh air, to soothe the spirit, cool and refreshing air, protection health.
Described chloride formula Chinese herbal medicine air disinfectant comprises the composition of following weight portion:
Stability chloride granular system A 30-70 part
Activated particle system B 10-50 part
Chinese herbal medicine granular system C 20-50 part.
Preferably, described chloride formula Chinese herbal medicine air disinfectant comprises the composition of following weight portion:
Stability chloride granular system A 40-60 part
Activated particle system B 20-40 part
Chinese herbal medicine granular system C 30-40 part.
Further preferably, described chloride formula Chinese herbal medicine air disinfectant comprises the composition of following weight portion:
The chloride granular system A of stability 50 parts
Activated particle system B 20 parts
Chinese herbal medicine granular system C 30 parts.
In above-mentioned chloride formula Chinese herbal medicine air disinfectant:
Described weight portion can be the unit of weights well known in the art such as g, kg, ton, also can be its multiple, as 1/10,1/100,10 times, 100 times etc.
Wherein, chloride metal salt particle mixes with the weight ratio of stability carrier by 1:0.5-1:2 by the preparation method of stability chloride granular system A, and preparation particle size is the particle of 0.1-3mm.
Preferably, the particle size of the chloride granular system A of described stability is 1-2mm; Further preferably, the particle size of the chloride granular system A of described stability is 1.5mm.
Described chloride metal salt particle is one or more in sodium chlorite, potassium chlorite, barium chlorite.
Described stability carrier is one or more in diatomite, sepiolite, calcium chloride, lithium chloride, magnesium chloride, silica gel, zeolite, silica.
Wherein, activated particle composition mixes with the weight ratio of stability carrier by 1:0.5-1:2 by the preparation method of described activated particle system B, and preparation particle size is the particle of 0.1-3mm.
Preferably, the particle size of described activated particle system B is 1-2mm; Further preferably, the particle size of described activated particle system B is 1mm.
Described activated particle composition is one or more in citric acid, tartaric acid, oxalic acid, boric acid, sulfamic acid, sodium dihydrogen phosphate.
Described stability carrier is one or more in diatomite, sepiolite, calcium chloride, lithium chloride, magnesium chloride, silica gel, zeolite, silica.
Wherein, described Chinese herbal medicine granular system C is one or more in Chinese herbal medicine pulverized particles, Volatile Oil of Medicinal Herbs particle, Chinese herbal medicine extract particle.
The preparation method of described Chinese herbal medicine pulverized particles is: the herbal powder after pulverizing is prepared into the Chinese herbal medicine pulverized particles that particle size is 0.1-2mm.
Preferably, described herbal powder is rhizoma atractylodis, tarragon, cloves, chrysanthemum, peppermint, Chinese prickly ash or Dahurian Angelica Root.Described herbal powder is all commercially available.
Described Chinese herbal medicine pulverized particles is the mixture of one or more in the pulverized particles made of said herbal medicine powder.
The preparation method of described Volatile Oil of Medicinal Herbs particle is after the ratio of Chinese herbal medicine liquid volatile oil and cured granulate by volume weight ratio (ml/g) 1:2-10 being mixed, preparation particle size is the particle of 0.1-2mm, dry, make its water content be no more than 5%, obtain described Volatile Oil of Medicinal Herbs particle.Described envelope-bulk to weight ratio is that 1ml Chinese herbal medicine liquid volatile oil and 2-10g cured granulate mix.
Preferably, described Chinese herbal medicine liquid volatile oil is Moschus, rhizoma atractylodis, cassia twig, schizonepeta, wrinkled giant hyssop, tarragon, the capsule of weeping forsythia, cloves or lemon volatile oil.Described Chinese herbal medicine liquid volatile oil is all commercially available, or prepares by the following method: described Chinese herbal medicine liquid volatile oil is prepared by steam distillation, microwave extraction method, supercritical carbon dioxide fluid extraction and obtained.
The method utilizing steam distillation to prepare Chinese herbal medicine liquid volatile oil is: more soft the organizing such as leaf, flower of Chinese herbal medicine does not need can directly to distill through pre-treatment, harder the organizing such as tubers, through cutting, pulverizing the extraction rate improving volatile oil, and powder is crossed No. 3 and sieved.Accurately take a certain amount of Chinese herbal medicine or herbal powder, be immersed in (ratio of Chinese herbal medicine and distilled water is w/v (g/ml) 1:5-10) in the distilled water of 5-10 times of volume, in steam distillation device, extract 6h, collect distillate; In distillate, add NaCl to saturated, use extracted with diethyl ether 3 times after leaving standstill, combining extraction liquid, anhydrous Na
2sO
4drying, filters, and revolves to steam to reclaim ether, and 40 DEG C of vacuum drying 1h, obtain the Chinese herbal medicine liquid volatile oil of peat-reek.
When preparing described Volatile Oil of Medicinal Herbs particle, the cured granulate used comprises silica gel, cyclodextrin, gel or resin.
Described Volatile Oil of Medicinal Herbs particle is the mixture of one or more that said herbal medicine evaporates in oil and the volatile oil particle that obtains of cured granulate.
The preparation method of described Chinese herbal medicine extract particle is after the ratio of extracts of Chinese herbal medicine and cured granulate by volume weight ratio (ml/g) 1:2-10 being mixed, preparation particle size is the particle of 0.1-2mm, dry, make its water content be no more than 5%, obtain described Chinese herbal medicine extract particle.Described envelope-bulk to weight ratio is that 1ml extracts of Chinese herbal medicine and 2-10g cured granulate mix.
Preferably, described extracts of Chinese herbal medicine is coptis root, tarragon, cloves, cordate houttuynia, the root of large-flowered skullcap or folium isatidis extract.Described extracts of Chinese herbal medicine is all commercially available, or is prepared by water extraction.
The method utilizing water extraction to extract extracts of Chinese herbal medicine is: more soft the organizing such as leaf, flower of Chinese herbal medicine does not need can directly to distill through pre-treatment, harder the organizing such as tubers, through cutting, pulverizing the extraction rate improving volatile oil, and powder crosses No. 3 sieves.Get appropriate Chinese herbal medicine or herbal powder, be immersed in (ratio of Chinese herbal medicine and distilled water is w/v (g/ml) 1:5-10) in the distilled water of 5-10 times of volume, be heated to seethe with excitement and keep 0.5-2h, pouring out filtrate; Add the distilled water of 2-5 times of volume again with legal system filtrate (ratio pouring out the precipitation after filtrate and distilled water is w/v (g/ml) 1:2-5), merge twice filtrate, after filtered through gauze twice, the amount of liquid being concentrated into 2-5 times of volume through 60 DEG C of rotary evaporations gets final product (Chinese herbal medicine taken is w/v (g/ml) 1:2-5 with the ratio of concentrated amount of liquid).
When preparing described Chinese herbal medicine extract particle, the cured granulate used comprises silica gel, gel, resin or cyclodextrin.
Described Chinese herbal medicine extract particle is the mixture of one or more in the extract particles that obtains of said herbal medicine extract and cured granulate.
Present invention also offers the preparation method of described chloride formula Chinese herbal medicine air disinfectant, chloride for stability granular system A and Chinese herbal medicine granular system C, for take each composition by proportioning, mixes, then adds activated particle system B by described method, and mixing, to obtain final product.
Present invention also offers the application of above-mentioned chloride formula Chinese herbal medicine air disinfectant in the preparation of preparation expelling parasite, sterilization or fresh air.
When using chloride formula Chinese herbal medicine air disinfectant of the present invention, sachet, cutting ferrule, toy, ornaments can be equipped in and other can individual wears, the place of indoor suspension, upholstery uses.
Chloride formula Chinese herbal medicine air disinfectant of the present invention has following technique effect:
(1) in chloride formula Chinese herbal medicine air disinfectant of the present invention, the chloride granular system A of stability absorption moisture in air while, under the acidization of activated particle system B, can slow releasing chlorine dioxide.Chinese herbal medicine granular system C can not only strengthen the sterilizing effect of chlorine dioxide, and can alleviate the penetrating odor of chlorine dioxide, makes air more pure and fresh, pleasant.
(2) in chloride formula Chinese herbal medicine air disinfectant of the present invention, by stability chloride granular system A slow releasing chlorine dioxide, chlorine dioxide is the strong fungicide of a kind of safe, efficient, the wide spectrum that World Health Organization confirms, its sterilizing ability is 5 times of chlorine, has good killing and inhibition for bacterium, virus.Air sanitizer of the present invention is the Chlorine dioxide production of slowly-releasing, slowly can discharge the chlorine dioxide of low concentration in a long time constantly, effectively kill the pathogenic microorganism in air, prevent indoor article from going mouldy in a humid environment, sterilization and the double effect of sterilization are carried out to air.
(3) in chloride formula Chinese herbal medicine air disinfectant of the present invention, the herbal component rhizoma atractylodis of Chinese herbal medicine granular system C, cassia twig, cordate houttuynia, tarragon, chrysanthemum, schizonepeta, cloves, wrinkled giant hyssop, coptis root, the root of large-flowered skullcap, folium isatidis, Moschus, lemon, the root of Dahurain angelica, peppermint, there is fragrance and keep away dirty, detoxifying and descending turbid, effects such as epidemic prevention, sterilizing of getting rid of evils, and the aromatic odor that Chinese herbal medicine gives out there are fresh air, adjustment mood, improve the effect of immunity.Volatile Oil of Medicinal Herbs, has another name called essential oil, and being the general name of the volatility oily composition not miscible with water that a class can obtain with steam distillation, is an active component.Volatile Oil of Medicinal Herbs has anti-inflammatory, antiallergy, antimicrobial, anti-sudden change and anticancer, anthelmintic action, enzyme inhibition, effect etc. to central nervous system and respiratory system.
(4) preparation technology of chloride formula Chinese herbal medicine air disinfectant of the present invention is simple, and each material composition is easy to get.
(5) expelling parasite of Chinese herbal medicine, sterilizing, health-care effect effectively combine with the sterilization of chlorine dioxide by the present invention; the sterilizing of double Chinese herbal medicine and chlorine dioxide is in one simultaneously; while slow releasing chlorine dioxide; eliminate the penetrating odor of chlorine dioxide; can fresh air; soothe the spirit, cool and refreshing air; protection health; for people provide a safety, comfortable environment; can be used for the fields such as purification with fresh air, industry and family expenses gas defence, there are wide using value and market prospects.
Embodiment
Following examples for illustration of the present invention, but are not used for limiting the scope of the invention.Without departing from the spirit and substance of the case in the present invention, the amendment do the inventive method, step or condition or replacement, all belong to scope of the present invention.
If do not specialize, experiment material used in the embodiment of the present invention, reagent and instrument etc. are all commercially available, if specifically do not indicate, and the conventional means that technological means used in embodiment is well known to the skilled person.
The preparation method of described Volatile Oil of Medicinal Herbs particle is after the ratio of Chinese herbal medicine liquid volatile oil and cured granulate by volume weight ratio (ml/g) 1:2-10 being mixed, preparation particle size is the particle of 0.1-2mm, dry, make its water content be no more than 5%, obtain described Volatile Oil of Medicinal Herbs particle.Described envelope-bulk to weight ratio is that 1ml Chinese herbal medicine liquid volatile oil and 2-10g cured granulate mix.
Described Chinese herbal medicine liquid volatile oil is Moschus, rhizoma atractylodis, cassia twig, schizonepeta, wrinkled giant hyssop, tarragon, the capsule of weeping forsythia, cloves or lemon volatile oil.Described Chinese herbal medicine liquid volatile oil is all commercially available, or prepares by the following method: described Volatile Oil of Medicinal Herbs is by steam distillation, microwave extraction method, supercritical CO
2extraction is prepared and obtains.
The method utilizing steam distillation to prepare Chinese herbal medicine liquid volatile oil is: more soft the organizing such as leaf, flower of Chinese herbal medicine does not need can directly to distill through pre-treatment, harder the organizing such as tubers, through cutting, pulverizing the extraction rate improving volatile oil, and powder is crossed No. 3 and sieved.Accurately take a certain amount of Chinese herbal medicine or herbal powder, be immersed in (ratio of Chinese herbal medicine and distilled water is w/v (g/ml) 1:5-10) in the distilled water of 5-10 times of volume, in steam distillation device, extract 6h, collect distillate; In distillate, add NaCl to saturated, use extracted with diethyl ether 3 times after leaving standstill, combining extraction liquid, anhydrous Na
2sO
4drying, filters, and revolves to steam to reclaim ether, and 40 DEG C of vacuum drying 1h, obtain the Chinese herbal medicine liquid volatile oil of peat-reek.
When preparing described Volatile Oil of Medicinal Herbs particle, the cured granulate used comprises silica gel, cyclodextrin, gel or resin.
The preparation method of described Chinese herbal medicine extract particle is after the ratio of extracts of Chinese herbal medicine and cured granulate by volume weight ratio (ml/g) 1:2-10 being mixed, preparation particle size is the particle of 0.1-2mm, dry, make its water content be no more than 5%, obtain described Chinese herbal medicine extract particle.Described envelope-bulk to weight ratio is that 1ml extracts of Chinese herbal medicine and 2-10g cured granulate mix.
Described extracts of Chinese herbal medicine is coptis root, tarragon, cloves, cordate houttuynia, the root of large-flowered skullcap or folium isatidis extract.Described extracts of Chinese herbal medicine is all commercially available, or is prepared by water extraction.
The method utilizing water extraction to extract extracts of Chinese herbal medicine is: more soft the organizing such as leaf, flower of Chinese herbal medicine does not need can directly to distill through pre-treatment, harder the organizing such as tubers, through cutting, pulverizing the extraction rate improving volatile oil, and powder crosses No. 3 sieves.Get appropriate Chinese herbal medicine or herbal powder, be immersed in (ratio of Chinese herbal medicine and distilled water is w/v (g/ml) 1:5-10) in the distilled water of 5-10 times of volume, be heated to seethe with excitement and keep 0.5-2h, pouring out filtrate; Add the distilled water of 2-5 times of volume again with legal system filtrate (ratio pouring out the precipitation after filtrate and distilled water is w/v (g/ml) 1:2-5), merge twice filtrate, after filtered through gauze twice, the amount of liquid being concentrated into 2-5 times of volume through 60 DEG C of rotary evaporations gets final product (Chinese herbal medicine taken is w/v (g/ml) 1:2-5 with the ratio of concentrated amount of liquid).
When preparing described Chinese herbal medicine extract particle, the cured granulate used comprises silica gel, gel, resin or cyclodextrin.
Embodiment 1
(1) prepare stability chloride granular system A: mixed by the weight ratio of 1:1 with stability carrier zeolite by chloride slaine sodium chlorite, preparation particle size is the particle of 1.5mm;
(2) prepare activated particle system B: mixed by the weight ratio of 1:1 with stability carrier zeolite by activated particle composition citric acid, preparation particle size is the particle of 1.5mm;
(3) Chinese herbal medicine granular system C is prepared: the oil that evaporated by Moschus mixes by the envelope-bulk to weight ratio (ml/g) of 1:5 with cyclodextrin, is prepared into the particle that particle size is 1mm, dries, makes its water content be no more than 5%, obtain Moschus volatile oil particle;
(4) chloride for 50g stability granular system A is mixed with 30g Chinese herbal medicine granular system C; Said mixture is mixed with the activated particle system B of 20g, to obtain final product.
Embodiment 2
(1) prepare stability chloride granular system A: mixed with the weight ratio of stability carrier diatomaceous earth by 1:0.5 by chloride slaine sodium chlorite, preparation particle size is the particle of 2mm;
(2) prepare activated particle system B: mixed by the weight ratio of 1:1 with stability carrier zeolite by activated particle composition tartaric acid, preparation particle size is the particle of 1.5mm;
(3) prepare Chinese herbal medicine granular system C: Jiang Cangmu, cloves, wrinkled giant hyssop evaporate oil content not and cured granulate silica gel mix by the envelope-bulk to weight ratio (ml/g) of 1:2, be prepared into the particle that particle size is 1mm, dry, make its water content not higher than 5%, obtain grey wood, cloves, wrinkled giant hyssop three kinds of Volatile Oil of Medicinal Herbs particles respectively, by described three kinds of Volatile Oil of Medicinal Herbs particles mixing, obtained Chinese herbal medicine granular system C;
(4) chloride for 60g stability granular system A is mixed with 50g Chinese herbal medicine granular system C; Said mixture is mixed with the activated particle system B of 30g, to obtain final product.
Embodiment 3
(1) prepare stability chloride granular system A: mixed by the weight ratio of 1:1 with stability carrier sepiolite by chloride slaine potassium chlorite, preparation particle size is the particle of 1.5mm;
(2) prepare activated particle system B: mixed by the weight ratio of 1:0.5 with stability carrier sepiolite by activated particle composition oxalic acid, preparation particle size is the particle of 1.5mm;
(3) Chinese herbal medicine granular system C is prepared: after being mixed by the envelope-bulk to weight ratio (ml/g) of 1:7 with cured granulate resin respectively by the extract of cloves, coptis root, preparation particle size is the particle of 1mm, dry, make its water content not higher than 5%, obtain cloves, coptis root two kinds of Chinese herbal medicine extract particles respectively, by described two kinds of Chinese herbal medicine extract particles mixing, obtained Chinese herbal medicine granular system C;
(4) chloride for 70g stability granular system A is mixed with 20g Chinese herbal medicine granular system C; Said mixture is mixed with the activated particle system B of 30g, to obtain final product.
Embodiment 4
(1) prepare stability chloride granular system A: by chloride slaine sodium chlorite, potassium chlorite, the mixture of barium chlorite mixes by the weight ratio of 1:2 with stability carrier sepiolite, and preparation particle size is the particle of 1.5mm;
(2) prepare activated particle system B: mixed by the weight ratio of 1:2 with stability carrier sepiolite by activated particle composition citric acid, preparation particle size is the particle of 1.5mm;
(3) Chinese herbal medicine granular system C is prepared: grey wood, tarragon, peppermint cracker are pulverized respectively, powder after pulverizing is prepared into through granulator the particle that particle size is 1mm respectively, obtain grey wood, tarragon, peppermint three kinds of Chinese herbal medicine pulverized particles, by described three kinds of Chinese herbal medicine pulverized particles mixing, obtained Chinese herbal medicine granular system C;
(4) chloride for 70g stability granular system A is mixed with 30g Chinese herbal medicine granular system C; Said mixture is mixed with the activated particle system B of 30g, to obtain final product.
Embodiment 5
(1) prepare stability chloride granular system A: mixed with the weight ratio of stability carrier diatomaceous earth by 1:2 by chloride slaine sodium chlorite, preparation particle size is the particle of 2mm;
(2) prepare activated particle system B: mixed by the weight ratio of 1:0.5 with stability carrier sepiolite by the mixture of activated particle composition citric acid, sodium dihydrogen phosphate, preparation particle size is the particle of 1.5mm;
(3) Chinese herbal medicine granular system C is prepared: other for the oil content that evaporates of lemon, cassia twig, schizonepeta and cured granulate cyclodextrin are mixed by the envelope-bulk to weight ratio (ml/g) of 1:3, be prepared into the particle that particle size is 1mm, dry, make its water content not higher than 5%, obtain lemon, cassia twig, schizonepeta three kinds of Volatile Oil of Medicinal Herbs particles respectively, by described three kinds of Volatile Oil of Medicinal Herbs particles mixing, obtained Chinese herbal medicine granular system C;
(4) chloride for 30g stability granular system A is mixed with 50g Chinese herbal medicine granular system C; Said mixture is mixed with the activated particle system B of 10g, to obtain final product.
Embodiment 6
(1) prepare stability chloride granular system A: mixed by the weight ratio of 1:0.5 by the mixture of the mixture of chloride slaine sodium chlorite, barium chlorite with stability carrier sepiolite, calcium chloride, preparation particle size is the particle of 1.5mm;
(2) prepare activated particle system B: mixed with the weight ratio of stability carrier diatomaceous earth by 1:2 by the mixture of activated particle composition citric acid, tartaric acid, oxalic acid, preparation particle size is the particle of 2mm;
(3) Chinese herbal medicine granular system C is prepared: the oil that evaporated by tarragon mixes by the envelope-bulk to weight ratio (ml/g) of 1:5 with cured granulate cyclodextrin, be prepared into the particle that particle size is 1mm, dry, make its water content not higher than 5%, obtain described Chinese herbal medicine granular system C;
(4) chloride for 40g stability granular system A is mixed with 40g Chinese herbal medicine granular system C; Said mixture is mixed with the activated particle system B of 50g, to obtain final product.
Experimental example 1 bactericidal effect
1, laboratory sample
Arrange 6 experimental group and 2 control groups, the laboratory sample of experimental group 1-6 is respectively the obtained chloride formula Chinese herbal medicine air disinfectant of embodiment 1-6; Control group 1 is blank; The laboratory sample of control group 2 is the air sanitizer (air sanitizer of control group 2 is the air sanitizer not containing Chinese herbal medicine granular system C in embodiment 1) obtained as follows:
(1) prepare stability chloride granular system A: mixed by the weight ratio of 1:1 with stability carrier zeolite by chloride slaine sodium chlorite, preparation particle size is the particle of 1.5mm;
(2) prepare activated particle system B: mixed by the weight ratio of 1:1 with stability carrier zeolite by activated particle composition citric acid, preparation particle size is the particle of 1.5mm;
(3) the activated particle system B of 50g stability chloride granular system A and 20g is mixed, to obtain final product.
2, experimental technique
Control group 1: the agar culture plate 5 being coated with 20 μ l Escherichia coli bacteria suspension (5000cfu/ml) puts into four angles and center (incubator is not containing any air sanitizer) of 37 DEG C of incubators respectively.Take out medium after 24h observe bacterium colony and count.Observe weekly once, Continuous Observation 5 times.
Control group 2 and experimental group 1-6: first, the chloride formula Chinese herbal medicine air disinfectant that air sanitizer obtained for control group 2 or embodiment 1-6 obtain is put into 37 DEG C of incubators, the agar culture plate 5 being coated with 20 μ l Escherichia coli bacteria suspension (5000cfu/ml) after 1h puts into incubator, as control group 1 operates equally.
Result is as shown in table 1.
Table 1 chloride formula Chinese herbal medicine air disinfectant bactericidal effect (clump count)
As can be seen from Table 1, without any air sanitizer in control group 1, Escherichia coli are well-grown on agar culture plate, and average colony number is 494; After putting into air sanitizer in control group 2 in incubator, then put into and be coated with colibacillary agar culture plate, result shows, the air sanitizer of control group 2 has certain killing action to Escherichia coli, and average colony number is 1; After experimental group 1-6 has put into the obtained chloride formula Chinese herbal medicine air disinfectant of embodiment of the present invention 1-6 respectively in incubator, put into again and be coated with colibacillary agar culture plate, result shows, after 24h, Escherichia coli are all killed, and average colony number is almost 0, be obviously better than control group 1 and control group 2.
To sum up show, the mediation effect of Chinese herbal medicine uniqueness effectively combines with the bactericidal action of chloride particle by chloride formula Chinese herbal medicine air disinfectant of the present invention, the sterilizing of double Chinese herbal medicine and chlorine dioxide is integrated, enhance the sterilizing effect of chlorine dioxide, to Escherichia coli, there is extremely strong killing effect.
Experimental example 2 irritation test
1, laboratory sample
Arrange 6 experimental group and 2 control groups, the laboratory sample of 6 experimental group is respectively the obtained chloride formula Chinese herbal medicine air disinfectant of embodiment 1-6, and the laboratory sample of 2 control groups is respectively chlorine and lemon.
2, experimental technique
Chlorine is as the strongest control group of excitant, and having similar penetrating odor to chlorine dioxide, have intense stimulus, is 10 points by its excitant intensity signature; Its excitant intensity signature, as non-irritating control group, is 0 point by lemon.
Select the adult experimenter that 20 healthy, and it is carried out random label from 1-20; In the mode of touch system, every experimenter all gives a mark to the chloride formula Chinese herbal medicine air disinfectant that chlorine, lemon and embodiment 1-6 obtain, and mark higher explanation excitant is stronger.
The results are shown in Table 2.
The excitant of the chloride formula Chinese herbal medicine air disinfectant of table 2 detects
As can be seen from Table 2, in 6 experimental group and 2 control groups, chlorine has the strongest excitant (chlorine and chlorine dioxide have similar penetrating odor, have intense stimulus), and scoring is 10; And the smell of lemon is the most suitable, scoring is 0.In the chloride formula Chinese herbal medicine air disinfectant that embodiment 1-6 is obtained, the excitant of the chloride formula Chinese herbal medicine air disinfectant that embodiment 5 is obtained is the most weak, scoring is 0.45, and the excitant of the chloride formula Chinese herbal medicine air disinfectant that embodiment 2 and embodiment 6 obtain is the strongest, and scoring is 1.50.
This experiment effectively describes the penetrating odor that chloride formula Chinese herbal medicine air disinfectant of the present invention obviously can reduce chlorine dioxide, can fresh air, soothes the spirit, cool and refreshing air, protection health.
In sum; the mediation effect of Chinese herbal medicine uniqueness effectively combines with the bactericidal action of chloride particle by chloride formula Chinese herbal medicine air disinfectant of the present invention; the sterilizing of double Chinese herbal medicine and chlorine dioxide is integrated; enhance the sterilizing effect of chlorine dioxide; obviously can reduce again the penetrating odor of chlorine dioxide; fresh air, soothes the spirit, cool and refreshing air, protection health.
Although above with general explanation, embodiment and test, the present invention is described in detail, and on basis of the present invention, can make some modifications or improvements it, this will be apparent to those skilled in the art.Therefore, these modifications or improvements without departing from theon the basis of the spirit of the present invention, all belong to the scope of protection of present invention.
Claims (10)
1. a chloride formula Chinese herbal medicine air disinfectant, is characterized in that, described chloride formula Chinese herbal medicine air disinfectant comprises the composition of following weight portion:
Stability chloride granular system A 30-70 part
Activated particle system B 10-50 part
Chinese herbal medicine granular system C 20-50 part.
2. chloride formula Chinese herbal medicine air disinfectant according to claim 1, is characterized in that, described chloride formula Chinese herbal medicine air disinfectant comprises the composition of following weight portion:
Stability chloride granular system A 40-60 part
Activated particle system B 20-40 part
Chinese herbal medicine granular system C 30-40 part.
3. chloride formula Chinese herbal medicine air disinfectant according to claim 1 and 2, it is characterized in that, chloride metal salt particle mixes with the weight ratio of stability carrier by 1:0.5-1:2 by the preparation method of stability chloride granular system A, and preparation particle size is the particle of 0.1-3mm; Preferably, described chloride metal salt particle is one or more in sodium chlorite, potassium chlorite, barium chlorite; Preferably, described stability carrier is one or more in diatomite, sepiolite, calcium chloride, lithium chloride, magnesium chloride, silica gel, zeolite, silica.
4. chloride formula Chinese herbal medicine air disinfectant according to claim 1 and 2, it is characterized in that, activated particle composition mixes with the weight ratio of stability carrier by 1:0.5-1:2 by the preparation method of described activated particle system B, and preparation particle size is the particle of 0.1-3mm; Preferably, described activated particle composition is one or more in citric acid, tartaric acid, oxalic acid, boric acid, sulfamic acid, sodium dihydrogen phosphate; Preferably, described stability carrier is one or more in diatomite, sepiolite, calcium chloride, lithium chloride, magnesium chloride, silica gel, zeolite, silica.
5. chloride formula Chinese herbal medicine air disinfectant according to claim 1 and 2, is characterized in that, described Chinese herbal medicine granular system C is one or more in Chinese herbal medicine pulverized particles, Volatile Oil of Medicinal Herbs particle, Chinese herbal medicine extract particle.
6. chloride formula Chinese herbal medicine air disinfectant according to claim 5, is characterized in that, the preparation method of described Chinese herbal medicine pulverized particles is: the herbal powder after pulverizing is prepared into the Chinese herbal medicine pulverized particles that particle size is 0.1-2mm; Preferably, described herbal powder is rhizoma atractylodis, tarragon, cloves, chrysanthemum, peppermint, Chinese prickly ash or Dahurian Angelica Root.
7. chloride formula Chinese herbal medicine air disinfectant according to claim 5, it is characterized in that, the preparation method of described Volatile Oil of Medicinal Herbs particle is after the ratio of Chinese herbal medicine liquid volatile oil and cured granulate by volume weight ratio 1:2-10 being mixed, preparation particle size is the particle of 0.1-2mm, dry, make its water content be no more than 5%, to obtain final product; Preferably, described Chinese herbal medicine liquid volatile oil is Moschus, rhizoma atractylodis, cassia twig, schizonepeta, wrinkled giant hyssop, tarragon, the capsule of weeping forsythia, cloves or lemon volatile oil; Preferably, described cured granulate comprises silica gel, cyclodextrin, gel or resin.
8. chloride formula Chinese herbal medicine air disinfectant according to claim 5, it is characterized in that, the preparation method of described Chinese herbal medicine extract particle is after the ratio of extracts of Chinese herbal medicine and cured granulate by volume weight ratio 1:2-10 being mixed, preparation particle size is the particle of 0.1-2mm, dry, make its water content be no more than 5%, to obtain final product; Preferably, described extracts of Chinese herbal medicine is coptis root, tarragon, cloves, cordate houttuynia, the root of large-flowered skullcap or folium isatidis extract; Preferably, described cured granulate comprises silica gel, cyclodextrin, gel or resin.
9. the preparation method of chloride formula Chinese herbal medicine air disinfectant described in any one of claim 1-8, it is characterized in that, described method is for take each composition by proportioning, chloride for stability granular system A and Chinese herbal medicine granular system C is mixed, add activated particle system B again, mixing, to obtain final product.
10. the application of chloride formula Chinese herbal medicine air disinfectant described in any one of claim 1-8 in the preparation of preparation expelling parasite, sterilization or fresh air.
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