CN104288388A - Medicament for treating acute inflammatory demyelinating polyneuropathies and preparation method of medicament - Google Patents
Medicament for treating acute inflammatory demyelinating polyneuropathies and preparation method of medicament Download PDFInfo
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Abstract
The invention relates to a medicament for treating acute inflammatory demyelinating polyneuropathies and a preparation method of the medicament. The medicament is prepared from the following components in parts by weight: 9-14 parts of oryzanol, 6-11 parts of Chinese taxillus twigs, 5-10 parts of obscured homalomena rhizome, 6-12 parts of frankincense, 4-11 parts of towel gourd vegetable sponge, 5-10 parts of common curculigo rhizome, 6-9 parts of pitaya flower, 5-8 parts of claoxylon polot, 5-11 parts of root of water nightshade, 6-12 parts of red madder, 5-10 parts of amur corktree bark, 5-10 parts of conical redpepper fruits, 6-11 parts of mountain oranges, 5-12 parts of songaria cynomorium herb, 5-10 parts of wolfberry root, 6-11 parts of eucommia bark, 5-10 parts of officinal magnolia bark, 4-8 parts of caper euphorbia seeds and 5-9 parts of solidago Canadensis. The medicament provided by the invention has a great effect on treatment of acute inflammatory demyelinating polyneuropathies. The preparation method comprises the processes of grinding, sealing and the like, and the method is simple, applicable, easy to operate and conductive to popularization and application.
Description
Technical field
The present invention relates to medicine of a kind of Guillain Barre syndrome and preparation method thereof.
Background technology
Guillain Barre syndrome, major lesions is nerve root peripheral nerve struvite demyelination widely, sometimes also involves spinal meninges, spinal cord and brain, Clinical symptoms disappears to develop the unable companion's tendon reflex of extremity symmetry rapidly.There is oblongata and paralysis of respiratory muscle and threat to life in the person of being in a bad way.Primary disease is mainly in person between twenty and fifty and child, and male is slightly many, and Summer and winter is slightly many.The patient of about 2/3 has upper respiratory tract or digestive tract infection history in premorbid a few days to several weeks.At present, treat this disease and generally adopt mode, the Western medicine oral way such as plasma exchange, immunoglobulin intravenous drip, aforesaid way therapeutic process patient bears considerable distress, and side effect is comparatively large, even there will be the symptoms such as heart failure, there is certain risk.
Summary of the invention
The object of this invention is to provide medicine of a kind of Guillain Barre syndrome and preparation method thereof, it adopts raw material of Chinese medicine to add Western medicine powder composition, and therapeutic effect is remarkable.Manufacture method is simple.
Described object is achieved by the following scheme:
A kind of medicine of Guillain Barre syndrome, be prepared from by following ratio of weight and number, oryzanol 9-14 part, Herba Taxilli 6-11 part, Rhizoma Homalomenae 5-10 part, Olibanum 6-12 part, Retinervus Luffae Fructus 4-11 part, Rhizoma Curculiginis 5-10 part, overlord spend 6-9 part, Ramulus et Folium Claoxyli 5-8 part, golden button head 5-11 part, red Radix Rubiae 6-12 part, Cortex Phellodendri 5-10 part, Fructus Capsici 5-10 part, Fructus Melodini Suaveolentis 6-11 part, Herba Cynomorii 5-12 part, boxthorn root 5-10 part, Cortex Eucommiae 6-11 part, Cortex Magnoliae Officinalis 5-10 part, Semen Euphorbiae 4-8 part, Herba Solidaginis 5-9 part.
Preferred version 1:
Be prepared from by following ratio of weight and number, oryzanol 9 parts, Herba Taxilli 11 parts, Rhizoma Homalomenae 8 parts, Olibanum 12 parts, Retinervus Luffae Fructus 4 parts, Rhizoma Curculiginis 7 parts, overlord spend 7 parts, Ramulus et Folium Claoxyli 8 parts, 5 parts, golden button head, 6 parts, red Radix Rubiae, Cortex Phellodendri 10 parts, Fructus Capsici 5 parts, Fructus Melodini Suaveolentis 9 parts, Herba Cynomorii 9 parts, boxthorn root 10 parts, the Cortex Eucommiae 11 parts, Cortex Magnoliae Officinalis 5 parts, Semen Euphorbiae 6 parts, Herba Solidaginis 7 parts.
Preferred version 2:
Be prepared from by following ratio of weight and number, oryzanol 11 parts, Herba Taxilli 8 parts, Rhizoma Homalomenae 5 parts, Olibanum 6 parts, Retinervus Luffae Fructus 7 parts, Rhizoma Curculiginis 5 parts, overlord spend 9 parts, Ramulus et Folium Claoxyli 5 parts, 8 parts, golden button head, 10 parts, red Radix Rubiae, Cortex Phellodendri 7 parts, Fructus Capsici 10 parts, Fructus Melodini Suaveolentis 11 parts, Herba Cynomorii 5 parts, boxthorn root 8 parts, the Cortex Eucommiae 6 parts, Cortex Magnoliae Officinalis 7 parts, Semen Euphorbiae 8 parts, Herba Solidaginis 5 parts.
Preferred version 3:
Be prepared from by following ratio of weight and number, oryzanol 14 parts, Herba Taxilli 6 parts, Rhizoma Homalomenae 10 parts, Olibanum 9 parts, Retinervus Luffae Fructus 11 parts, Rhizoma Curculiginis 10 parts, overlord spend 6 parts, Ramulus et Folium Claoxyli 6 parts, 11 parts, golden button head, 12 parts, red Radix Rubiae, Cortex Phellodendri 5 parts, Fructus Capsici 8 parts, Fructus Melodini Suaveolentis 6 parts, Herba Cynomorii 12 parts, boxthorn root 5 parts, the Cortex Eucommiae 9 parts, Cortex Magnoliae Officinalis 10 parts, Semen Euphorbiae 4 parts, Herba Solidaginis 9 parts.
Preparation method is prepared from by following steps:
(1) by above-mentioned raw material of Chinese medicine, removing impurity, dries, grinds powdered, mix homogeneously; (2) seal in the bucket above-mentioned raw material of Chinese medicine being placed on silvery, deposit 10 days, taking-up kraft paper is wrapped, then dries in the shade 2 days; (3) by oryzanol and described Chinese medicinal powder uniform stirring, incapsulate.
Each raw material function:
Oryzanol, mainly improves autonomic nervous dysfunction, improves incretion balance obstacle and spiritual nervous disorder, therefore has certain regulating action to neurasthenia patient; Energy stabilizing the emotions, anxiety reduction and tense situation simultaneously, and improving water flood; Also be usually used in the auxiliary treatment of premenstrual tension syndrome, climacteric syndrome.
Herba Taxilli, function: invigorating the liver and kidney, except rheumatism, bone and muscle strengthening, nourishing blood and preventing abortion.
Rhizoma Homalomenae, effect and effect: Rhizoma Homalomenae has wind-damp dispelling, bone and muscle strengthening, alleviating pain and detumescence effect.
Olibanum, effect and effect: promoting blood circulation and stopping pain relaxing muscles and tendons.
Retinervus Luffae Fructus, function: heat-clearing and toxic substances removing, promoting blood circulation to remove obstruction in the collateral, inducing diuresis to remove edema.
Rhizoma Curculiginis, function: kidney-replenishing, bone and muscle strengthening, cold expelling wets.
Overlord spends, function: clearing away lung-heat, cough-relieving are coughed.
Ramulus et Folium Claoxyli, function: dispel the wind, dry, subside a swelling, dissipating blood stasis.
Gold button head, function: dissipating blood stasis, detumescence, pain relieving.
Red Radix Rubiae, function: removing heat from blood, hemostasis, blood stasis removing blood, to invigorate blood circulation.
Cortex Phellodendri, function: rush down kidney fire, clearing away damp-heat, separates sore.
Fructus Capsici, function: expelling wind and cold, appetizing disappears stagnant, alleviating pain and detumescence.
Fructus Melodini Suaveolentis, function: activating QI, pain relieving.
Herba Cynomorii, function: kidney invigorating and YANG supporting controlling nocturnal emission with astringent drugs, intestine moistening, strong waist knee joint.
Boxthorn root, function: clear bone fire, to bring down a fever.
The Cortex Eucommiae, function: invigorating the liver and kidney, bone and muscle strengthening, antiabortive.
Cortex Magnoliae Officinalis, function: warming the middle warmer and descending qi, drying dampness to eliminate phlegm, relievings asthma.
Semen Euphorbiae, function: removing water retention by purgation is subsided a swelling, and removing blood stasis stimulates the menstrual flow.
Herba Solidaginis, dispelling wind and heat pathogens, heat-clearing and toxic substances removing, reducing swelling and alleviating pain, has antibiosis and antiviral functions.
The present invention adopts above formula, is in harmonious proportion at oryzanol, under the mutual and synergism between each medicine, has blood circulation promoting and blood stasis dispelling, clearing away heat-damp and promoting diuresis, soothing the liver eliminating stagnation, nourishing the liver and kidney, promoting flow of QI and blood, replenishing QI to invigorate the spleen, effect of bringing down a fever of detoxifying.The method of the invention simply easily operates, and is beneficial to and applies.
Detailed description of the invention
Elaborate the preferred embodiment of the present invention below.
Being incapsulated by 0.5 gram by powder, take medicine every day 3 times, each 4,10 days is a course for the treatment of.
embodiment 1:
A kind of medicine of Guillain Barre syndrome, be prepared from by following ratio of weight and number, oryzanol 9-14 part, Herba Taxilli 6-11 part, Rhizoma Homalomenae 5-10 part, Olibanum 6-12 part, Retinervus Luffae Fructus 4-11 part, Rhizoma Curculiginis 5-10 part, overlord spend 6-9 part, Ramulus et Folium Claoxyli 5-8 part, golden button head 5-11 part, red Radix Rubiae 6-12 part, Cortex Phellodendri 5-10 part, Fructus Capsici 5-10 part, Fructus Melodini Suaveolentis 6-11 part, Herba Cynomorii 5-12 part, boxthorn root 5-10 part, Cortex Eucommiae 6-11 part, Cortex Magnoliae Officinalis 5-10 part, Semen Euphorbiae 4-8 part, Herba Solidaginis 5-9 part.Preparation method is shown in embodiment 2.
Model case:
Lee, female, 36 years old, patient gave an oral account extremity acid Chen Wuli, and between two weeks, paralysis appears in lower limb gradually, numbness of the skin is micro-swollen, and heavy sensation of the whole body is stagnant, and fever of the body is not smooth, uncomfortable in chest, loose stool, urine swelling pain, red tongue yellow and greasy fur, is diagnosed as Guillain Barre syndrome.After giving a course for the treatment of of capsule for treating of the present invention, symptom is obviously improved, and after two courses for the treatment of, symptom disappears completely.Follow up a case by regular visits to 1 year without recurrence.
embodiment 2:
Be prepared from by following ratio of weight and number, oryzanol 9 parts, Herba Taxilli 11 parts, Rhizoma Homalomenae 8 parts, Olibanum 12 parts, Retinervus Luffae Fructus 4 parts, Rhizoma Curculiginis 7 parts, overlord spend 7 parts, Ramulus et Folium Claoxyli 8 parts, 5 parts, golden button head, 6 parts, red Radix Rubiae, Cortex Phellodendri 10 parts, Fructus Capsici 5 parts, Fructus Melodini Suaveolentis 9 parts, Herba Cynomorii 9 parts, boxthorn root 10 parts, the Cortex Eucommiae 11 parts, Cortex Magnoliae Officinalis 5 parts, Semen Euphorbiae 6 parts, Herba Solidaginis 7 parts.
Preparation method: be prepared from by following steps,
(1) by above-mentioned raw material of Chinese medicine, removing impurity, dries, grinds powdered, mix homogeneously; (2) seal in the bucket above-mentioned raw material of Chinese medicine being placed on silvery, deposit 10 days, taking-up kraft paper is wrapped, then dries in the shade 2 days; (3) by oryzanol and described Chinese medicinal powder uniform stirring, incapsulate.
Model case:
Chen, man, 38 years old, have intestinal infection symptom before patient's readme onset, after two weeks, the symmetrical unable companion's paraesthesia of extremity, expands from lower limb to upper limb, rear paralysis, lab testing discovery spinal fluid protein content is high and cell number normal, is diagnosed as Guillain Barre syndrome; After the course for the treatment of of oral capsule for treating of the present invention, symptom is obviously improved, and after three courses for the treatment of, symptom disappears completely; Check that all are normal; Follow up a case by regular visits to 1 year without recurrence.
embodiment 3:
Be prepared from by following ratio of weight and number, oryzanol 11 parts, Herba Taxilli 8 parts, Rhizoma Homalomenae 5 parts, Olibanum 6 parts, Retinervus Luffae Fructus 7 parts, Rhizoma Curculiginis 5 parts, overlord spend 9 parts, Ramulus et Folium Claoxyli 5 parts, 8 parts, golden button head, 10 parts, red Radix Rubiae, Cortex Phellodendri 7 parts, Fructus Capsici 10 parts, Fructus Melodini Suaveolentis 11 parts, Herba Cynomorii 5 parts, boxthorn root 8 parts, the Cortex Eucommiae 6 parts, Cortex Magnoliae Officinalis 7 parts, Semen Euphorbiae 8 parts, Herba Solidaginis 5 parts.Preparation method is identical with embodiment 2.
Model case:
Pan, man, 34 years old, patient's condition was more slow, and in three weeks, extremity flaccidity is soft gradually, soreness of the waist and knees, wasting and atrophy of muscle, with dizziness and tinnitus, the few tongue of red tongue, rapid pulse is thin, is diagnosed as Guillain Barre syndrome; After the course for the treatment of of oral capsule for treating of the present invention, symptom is improved, and after three courses for the treatment of, symptom disappears completely, follows up a case by regular visits to 1 year without recurrence.
embodiment 4:
Be prepared from by following ratio of weight and number, oryzanol 14 parts, Herba Taxilli 6 parts, Rhizoma Homalomenae 10 parts, Olibanum 9 parts, Retinervus Luffae Fructus 11 parts, Rhizoma Curculiginis 10 parts, overlord spend 6 parts, Ramulus et Folium Claoxyli 6 parts, 11 parts, golden button head, 12 parts, red Radix Rubiae, Cortex Phellodendri 5 parts, Fructus Capsici 8 parts, Fructus Melodini Suaveolentis 6 parts, Herba Cynomorii 12 parts, boxthorn root 5 parts, the Cortex Eucommiae 9 parts, Cortex Magnoliae Officinalis 10 parts, Semen Euphorbiae 4 parts, Herba Solidaginis 9 parts.Preparation method is identical with embodiment 2.
136 routine patients take, the oldest is 48 years old, minimum is 15 years old, after taking medicine one, effective person is 100%, extremity after a course for the treatment of of taking medicine are felt, can activist are slowly 68%, the symptom of paralysing after two courses for the treatment of of taking medicine alleviates, and breathing steady person is 88%, and after three courses for the treatment of of taking medicine, transference cure, breathing, normotensive are 98%.Symptom after four courses for the treatment of of taking medicine can all disappear.
Visible, medicine of the present invention is fine to treatment Guillain Barre syndrome effect.
Present embodiment does not just limit its protection domain to the exemplary illustration of this patent; those skilled in the art can also carry out local to it and change; as long as no the spirit exceeding this patent, be all considered as the equivalent replacement to this patent, all within the protection domain of this patent.
Claims (5)
1. the medicine of a Guillain Barre syndrome, it is characterized in that: be prepared from by following ratio of weight and number, oryzanol 9-14 part, Herba Taxilli 6-11 part, Rhizoma Homalomenae 5-10 part, Olibanum 6-12 part, Retinervus Luffae Fructus 4-11 part, Rhizoma Curculiginis 5-10 part, overlord spend 6-9 part, Ramulus et Folium Claoxyli 5-8 part, golden button head 5-11 part, red Radix Rubiae 6-12 part, Cortex Phellodendri 5-10 part, Fructus Capsici 5-10 part, Fructus Melodini Suaveolentis 6-11 part, Herba Cynomorii 5-12 part, boxthorn root 5-10 part, Cortex Eucommiae 6-11 part, Cortex Magnoliae Officinalis 5-10 part, Semen Euphorbiae 4-8 part, Herba Solidaginis 5-9 part.
2. the medicine of a kind of Guillain Barre syndrome according to claim 1, it is characterized in that: be prepared from by following ratio of weight and number, oryzanol 9 parts, Herba Taxilli 11 parts, Rhizoma Homalomenae 8 parts, Olibanum 12 parts, Retinervus Luffae Fructus 4 parts, Rhizoma Curculiginis 7 parts, overlord spend 7 parts, Ramulus et Folium Claoxyli 8 parts, 5 parts, golden button head, 6 parts, red Radix Rubiae, Cortex Phellodendri 10 parts, Fructus Capsici 5 parts, Fructus Melodini Suaveolentis 9 parts, Herba Cynomorii 9 parts, boxthorn root 10 parts, the Cortex Eucommiae 11 parts, Cortex Magnoliae Officinalis 5 parts, Semen Euphorbiae 6 parts, Herba Solidaginis 7 parts.
3. the medicine of a kind of Guillain Barre syndrome according to claim 1, it is characterized in that: be prepared from by following ratio of weight and number, oryzanol 11 parts, Herba Taxilli 8 parts, Rhizoma Homalomenae 5 parts, Olibanum 6 parts, Retinervus Luffae Fructus 7 parts, Rhizoma Curculiginis 5 parts, overlord spend 9 parts, Ramulus et Folium Claoxyli 5 parts, 8 parts, golden button head, 10 parts, red Radix Rubiae, Cortex Phellodendri 7 parts, Fructus Capsici 10 parts, Fructus Melodini Suaveolentis 11 parts, Herba Cynomorii 5 parts, boxthorn root 8 parts, the Cortex Eucommiae 6 parts, Cortex Magnoliae Officinalis 7 parts, Semen Euphorbiae 8 parts, Herba Solidaginis 5 parts.
4. the medicine of a kind of Guillain Barre syndrome according to claim 1, it is characterized in that: be prepared from by following ratio of weight and number, oryzanol 14 parts, Herba Taxilli 6 parts, Rhizoma Homalomenae 10 parts, Olibanum 9 parts, Retinervus Luffae Fructus 11 parts, Rhizoma Curculiginis 10 parts, overlord spend 6 parts, Ramulus et Folium Claoxyli 6 parts, 11 parts, golden button head, 12 parts, red Radix Rubiae, Cortex Phellodendri 5 parts, Fructus Capsici 8 parts, Fructus Melodini Suaveolentis 6 parts, Herba Cynomorii 12 parts, boxthorn root 5 parts, the Cortex Eucommiae 9 parts, Piao 10 parts, Semen Euphorbiae 4 parts, Herba Solidaginis 9 parts.
5. a preparation method for medicine described in claim 1, is characterized in that: be prepared from by following steps, and (1), by above-mentioned raw material of Chinese medicine, removing impurity, dries, grind powdered, mix homogeneously; (2) seal in the bucket above-mentioned raw material of Chinese medicine being placed on silvery, deposit 10 days, taking-up kraft paper is wrapped, then dries in the shade 2 days; (3) by oryzanol and described Chinese medicinal powder uniform stirring, incapsulate.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410576421.9A CN104288388A (en) | 2014-10-27 | 2014-10-27 | Medicament for treating acute inflammatory demyelinating polyneuropathies and preparation method of medicament |
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Cited By (4)
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| CN105012833A (en) * | 2015-08-15 | 2015-11-04 | 哈尔滨和谐旺科技开发有限公司 | Traditional Chinese medicine for treating polyneuropathy |
| CN105012571A (en) * | 2015-09-03 | 2015-11-04 | 哈尔滨泉兴科技有限公司 | Drug for treating demyelinating polyneuropathy and preparation method of drug |
| CN105168572A (en) * | 2015-09-03 | 2015-12-23 | 哈尔滨泉兴科技有限公司 | Medicine for fast treating inflammatory demyelinating polyneuropathy |
| CN105435055A (en) * | 2015-12-26 | 2016-03-30 | 哈尔滨和谐旺科技开发有限公司 | Traditional Chinese medicine for efficiently treating polyneuropathy |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105012833A (en) * | 2015-08-15 | 2015-11-04 | 哈尔滨和谐旺科技开发有限公司 | Traditional Chinese medicine for treating polyneuropathy |
| CN105012571A (en) * | 2015-09-03 | 2015-11-04 | 哈尔滨泉兴科技有限公司 | Drug for treating demyelinating polyneuropathy and preparation method of drug |
| CN105168572A (en) * | 2015-09-03 | 2015-12-23 | 哈尔滨泉兴科技有限公司 | Medicine for fast treating inflammatory demyelinating polyneuropathy |
| CN105435055A (en) * | 2015-12-26 | 2016-03-30 | 哈尔滨和谐旺科技开发有限公司 | Traditional Chinese medicine for efficiently treating polyneuropathy |
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