CN104273399A - Traditional Chinese medicine feed additive and usage thereof - Google Patents
Traditional Chinese medicine feed additive and usage thereof Download PDFInfo
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- CN104273399A CN104273399A CN201410610764.2A CN201410610764A CN104273399A CN 104273399 A CN104273399 A CN 104273399A CN 201410610764 A CN201410610764 A CN 201410610764A CN 104273399 A CN104273399 A CN 104273399A
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Abstract
The invention discloses a traditional Chinese medicine feed additive and usage thereof. The traditional Chinese medicine feed additive is prepared from the following components in parts by weight: 15-25 parts of houttuynia cordata, 10-20 parts of fathead tree, 10-25 parts of mussaenda pubescens, 10-20 parts of radix astragali, 12-26 parts of argyreia acuta, 10-25 parts of folium eriobotryae, 15-25 parts of radix bupleuri, 15-25 parts of auricled hedyotis herb and 3-10 parts of gypsum. After the traditional Chinese medicine feed additive is added into the daily ration of pigs, the production performance of the pigs can be improved, the average daily gain is remarkably increased, the feed conversion ratio is obviously reduced, and the incidence of diseases of the pigs is greatly reduced; furthermore, after the feed additive is used for 30 days and 60 days, the concentration of pig serum anti-infection related factor IL-1 and the concentration of pig serum anti-infection related factor TNF-alpha are remarkably improved compared with those of commercially available additives and contrasts.
Description
Technical field
The present invention relates to pig feed field, particularly relate to a kind of Chinese herbal feed additive and uses thereof.
Background technology
In the last few years, people urge long feed addictive using antibiotics and hormone medicine as diseases prevention in cultivation livestock and poultry process always, antibiotic " care plans " is fed in prevention bacteriosis to swinery, antibiotic plays irreplaceable effect really, and hormone medicine also have received certain effect as short long agent.And at present in China's cultivation industry, antibiotic is considered as the catholicon of prevention and therapy livestock and poultry disease, nowadays swine disease is day by day complicated, leaves antibiotic, and pig cannot be supported simply.But the long-term excessive use of this two classes medicine, the consequence that its side effect causes also appears day by day, is mainly manifested in: the normal flora after using antibiotic on the one hand in livestock and poultry body is damaged, and cause body intracellular metabolite disorderly, immunity degradation, more easily falls ill.Another aspect is that the residue problem of drug resistance and medicine causes harmful effect to human health, and the food-safety problem of current pork is precarious, is badly in need of the high medicine substitute antibiotics class of the new security of exploitation and the application of hormone medicine in livestock and poultry cultivation.
Summary of the invention
The object of the present invention is to provide a kind of production performance improving pig, average daily gain is significantly increased and immunity of organisms and premunition strengthen greatly, the Chinese herbal feed additive that in breeding process, the incidence of disease reduces greatly.
For achieving the above object, the invention provides a kind of health care for pig and urge long Chinese herbal feed additive, it is characterized in that: formulated by the composition of following weight portion: cordate houttuynia 15-25 part, nauclea officinalis 10-20 part, large cool rattan 10-25 part, Radix Astragali 10-20 part, white crane rattan 12-26 part, loguat leaf 10-25 part, radix bupleuri 15-25 part, auricled hedyotis herb 15-25 part, gypsum 3-10 part.
Preferably, formulated by the composition of following weight portion: cordate houttuynia 25 parts, nauclea officinalis 20 parts, large 25 parts, cool rattan, the Radix Astragali 20 parts, 26 parts, white crane rattan, loguat leaf 25 parts, radix bupleuri 25 parts, auricled hedyotis herb 25 parts, 10 parts, gypsum.
Described Chinese herbal feed additive, is characterized in that: preparation method is, each composition is dried or dried to water content less than 10%; Take each composition dried: cordate houttuynia, nauclea officinalis, large cool rattan, the Radix Astragali, white crane rattan, loguat leaf, radix bupleuri, auricled hedyotis herb and gypsum, respectively or mixing ultramicro grinding cross more than 300 mesh sieves, stir packing and get final product.Under this fineness condition, the sporoderm-broken rate of drug cell wall reaches more than 95%, is conducive to intracellular effective ingredient and fully exposes and discharge, and increase body to the absorptivity of medicine, improve the bioavailability of medicine, drug effect significantly improves, and onset is faster.
Described Chinese herbal feed additive is for raising the purposes of pig.
Described purposes is short long for making pig keep healthy.
Described purposes is to improve the production performance of pig, and average daily gain is significantly increased and immunity of organisms and premunition enhancing, in breeding process, the incidence of disease reduces.
Described Chinese herbal feed additive, for raising the purposes of pig, is characterized in that, the consumption of described Chinese herbal feed additive is 1000g/ ton daily ration.
The each composition of the present invention has following effect:
Cordate houttuynia: taste is pungent, cold, return lung channel.Can clearing heat and detoxicating, detumescence treat sore, promoting urination and removing dampness, clearing away heat to cure dysentery, stomach strengthening and digestion promoting, for control real heat, heat poison, damp evil be suffer from lung carbuncle, sore swollen toxin, retention of heat in the spleen and stomach etc.Modern pharmacology experiment shows, this product has antibacterial, antiviral, effect such as raising immunity of organisms, diuresis etc.
Nauclea officinalis: bitter, cold in nature.Function cures mainly: clearing heat and detoxicating, swelling and pain relieving.Treating acute tonsillitis, sphagitis, mastitis, enteritis, bacillary dysentery, urinary tract infections, cholecystitis, the ulcer of lower limb, dermatitis and eczema etc.Clinically be used for the treatment of inflammation and the infection of the upper respiratory tract.
Large cool rattan: nature and flavor: sweet, light, cool.Function cures mainly: clearing away summerheat, removing pattogenic heat from the blood and toxic material from the body.For poisoning, flu, bronchitis, tonsillitis, sphagitis, nephritic dropsy, enteritis etc.
The Radix Astragali: meridian distribution of property and flavor: sweet, tepor.Return lung, spleen, liver, kidney channel.Modern medicine study shows, the Radix Astragali has enhanced machine body immunity function, protects the liver, diuresis, resisting stress and antibacterial action etc. more widely.
White crane rattan: property is cool; Taste is bitter.Return lung channel.Function cures mainly: " south of the Five Ridges herbal " preventing phlegm from forming and stopping coughing, regulating blood circulation to dispel wind pathogen.Control heat to cough, asthma due to excessive phlegm etc." register planted by Guangxi medicine " dissolving phlegm, moistening lung, cough-relieving, hemostasis.Control tuberculosis, acute mastitis, scald.
Loguat leaf: meridian distribution of property and flavor: bitter, is slightly cold, lung, stomach warp.Function cures mainly: antibechic, eliminate the phlegm, relieving asthma and antibacterial action.
Radix bupleuri: nature and flavor are bitter, are slightly cold.Return liver, gallbladder channel.Have induce sweat, soothing the liver, rise effect of sun, for cold, fever, fevers and chills alternate, malaria, stagnation of QI due to depression of the liver etc.
Auricled hedyotis herb: taste is bitter; Property, flat.Function: clearing heat and moistening dryness, removing pattogenic heat from the blood and toxic material from the body.
Gypsum: meridian distribution of property and flavor: pungent, sweet, Great Cold.Attach to the lung and stomach meridians.Effect: clearing heat-fire, relieving restlessness is quenched the thirst, convergence myogenic.
The object of the present invention is to provide a kind of health care for pig to urge the Chinese herbal feed additive grown, in this formula, the combination of each component has complementary effect, and efficient, quick-acting, dispensing facilitates, does not produce drug resistance, has no side effect; This preparation method is easy, easily applies.
After adopting such scheme, long Chinese herbal feed additive is urged in a kind of health care for pig of the present invention, there is the effect of soothing the liver moistening lung, strengthening the spleen and replenishing qi, clearing heat-fire, removing pattogenic heat from the blood and toxic material from the body, relieving cough and reducing sputum, removing dampness to restore normal functioning of the stomach, promoting digestion, anti-inflammation, antiviral, develop immunitypty, improve resisting stress capability, regulate stomach and intestine function, strengthen immunity of organisms; Therefore, compared with prior art, have the following advantages:
One, formula is simple, and each compatibility of drugs exists complementary effect.There is the effects such as antibacterial, antiviral, develop immunitypty, use rear whole swinery seldom to fall ill;
Two, preparation is simple, draws materials easily, cheap, feeds conveniently;
Three, growth promoting effects, improve food conversion ratio, shorten breeding cycle, nontoxic residue-free, safe and reliable.Without the need to adding antibiotic or hormone medicine again;
Four, after using product of the present invention, swinery fur is smooth, and the colour of skin is ruddy.
Formula of the present invention is verified by embodiment, and apply Chinese medicine additive of the present invention and make an addition in swine rations, can improve the production performance of pig, average daily gain is significantly increased, and feed-weight ratio obviously reduces; The incidence of disease of pig reduces greatly; Meanwhile, to Swine serum anti-infective correlation factor IL-1 concentration with to Swine serum anti-infective correlation factor TNF-α concentration, compared with contrast with commercially available additive after 30 days, 60 days, also there is significant increase.
IL-1(interleukin 1) have another name called lymphocyte stimulating factor, its main physiological activity: 1, local action.Collaborative stimulation T cell activation, promotes B cell proliferation and secretory antibody, itself also has the effect that enhancing antibody is formed, thus strengthen immunity of organisms.2, systemic effect.A large amount of secretions of IL-1 are by causing general reaction after blood circulation, play various biological effect, one of them makes the neutrophil leucocyte in bone marrow cell storehouse be discharged into blood, and make it activation, strengthen its ability of killing and wounding pathogenic microorganism and migration ability, strengthen body premunition.TNF-α has the antivirus action of similar interferon, stops the synthesis of early protein matter, thus suppresses copying of virus.
Detailed description of the invention
Be described below in detail embodiments of the invention, the example of described embodiment is intended to for explaining the present invention, and can not be interpreted as limitation of the present invention.Unreceipted concrete technology or condition person in embodiment, according to the technology described by the document in this area or condition or carry out according to product description.Agents useful for same or the unreceipted production firm person of instrument, being can by the conventional products of commercial acquisition.
embodiment 1: the preparation of Chinese herbal feed additive
A long Chinese herbal feed additive is urged in health care for pig, formulated by weight by following compatibility: cordate houttuynia 15 parts, nauclea officinalis 10 parts, large 10 parts, cool rattan, the Radix Astragali 10 parts, 12 parts, white crane rattan, loguat leaf 10 parts, radix bupleuri 15 parts, auricled hedyotis herb 15 parts, 3 parts, gypsum.
The preparation method of long Chinese herbal feed additive is urged in described a kind of health care for pig, comprises the following steps:
Take Chinese medicine component: cordate houttuynia 15 parts, nauclea officinalis 10 parts, large 10 parts, cool rattan, the Radix Astragali 10 parts, 12 parts, white crane rattan, loguat leaf 10 parts, radix bupleuri 15 parts, auricled hedyotis herb 15 parts, 3 parts, gypsum.Ultramicro grinding crosses 300 mesh sieves, and stir packing and get final product.
embodiment 2: the preparation of Chinese herbal feed additive
A long Chinese herbal feed additive is urged in health care for pig, formulated by weight by following compatibility: cordate houttuynia 20 parts, nauclea officinalis 15 parts, large 18 parts, cool rattan, the Radix Astragali 15 parts, 19 parts, white crane rattan, loguat leaf 18 parts, radix bupleuri 20 parts, auricled hedyotis herb 20 parts, 6 parts, gypsum.The preparation method of long Chinese herbal feed additive is urged in described a kind of health care for pig, comprises the following steps:
Take Chinese medicine component: cordate houttuynia 20 parts, nauclea officinalis 15 parts, large 18 parts, cool rattan, the Radix Astragali 15 parts, 19 parts, white crane rattan, loguat leaf 18 parts, radix bupleuri 20 parts, auricled hedyotis herb 20 parts, 6 parts, gypsum.Ultramicro grinding crosses 300 mesh sieves, and stir packing and get final product.
embodiment 3: the preparation of Chinese herbal feed additive
A long Chinese herbal feed additive is urged in health care for pig, formulated by weight by following compatibility: cordate houttuynia 25 parts, nauclea officinalis 20 parts, large 25 parts, cool rattan, the Radix Astragali 20 parts, 26 parts, white crane rattan, loguat leaf 25 parts, radix bupleuri 25 parts, auricled hedyotis herb 25 parts, 10 parts, gypsum.The preparation method of long Chinese herbal feed additive is urged in described a kind of health care for pig, comprises the following steps:
Take Chinese medicine component: cordate houttuynia 25 parts, nauclea officinalis 20 parts, large 25 parts, cool rattan, the Radix Astragali 20 parts, 26 parts, white crane rattan, loguat leaf 25 parts, radix bupleuri 25 parts, auricled hedyotis herb 25 parts, 10 parts, gypsum.Ultramicro grinding crosses 300 mesh sieves, and stir packing and get final product.
The present invention is a kind of Chinese medicine powder, and consumption is 500-1000g/ ton feed, easy to use.
embodiment 4: compliance test result is tested
In pig farm, choose the long X Dasanyuans of all close, that sex ratio is identical, body weight is about 19 kg Du's X such as kind, parity, age in days child care pig of mixing do experimental subjects, embodiment one, two, three uses product of the present invention respectively, the commercially available health care growth-promoting additive (trade name: big porker falls apart of commercially available additive group, composition is thick wood-fern rhizome 30g, the fleece-flower root (system) 30g, Fructus Hordei Germinatus 500g, soya bean (stir-fry) 500g prepares), control group urgees long agent for not adding any health care.Animal subject feeding and management condition is basically identical.In feed, add product 1000g/ ton daily ration of the present invention, commercially available prod is added by its description.By interpolation 15 days, stop 15 days, then add 15 days, then the pattern of stopping 15 days is fed, raise 90 days altogether, often group does three repetitions, and result of the test is in table 1.
Effect criterion: after on-test every day viewing test pig the clinical change of the state of mind etc., and to make a record.
Morbidity: refer in whole process of the test there is fever, appetite declines, coughs, breathes, one or more symptom affecting the growth of pig normal growth of communicable disease, NCD etc. all belongs to morbidity.
Table 1 various dose Chinese medicine additive of the present invention affects table to pig growth performance
| Embodiment one | Embodiment two | Embodiment three | Commercially available additive | Control group | |
| Sum (head) before test | 60 | 60 | 60 | 60 | 60 |
| Off-test sum (head) | 60 | 60 | 60 | 60 | 60 |
| Gross weight (kg) before test | 1134 | 1129 | 1124 | 1131 | 1134 |
| Off-test gross weight (kg) | 4821 | 5074.8 | 5115 | 4636.6 | 4107 |
| Total augment weight (kg) | 3687 | 3945.8 | 3991 | 3505.6 | 2973 |
| Average weight increasing a day (kg) | 0.68 | 0.73 | 0.74 | 0.65 | 0.55 |
| Feed consumption total amount (kg) | 10360.5 | 10298.5 | 10177.1 | 10201.3 | 10465 |
| Feedstuff-meat ratio | 2.81 | 2.61 | 2.55 | 2.91 | 3.52 |
| Experimental period morbidity number (head) | 1 | 0 | 0 | 21 | 29 |
| The incidence of disease (%) | 1.7 | 0 | 0 | 35 | 48.3 |
Further illustrate using value of the present invention, in above-mentioned result of the test, the embodiment 3 of Selection effect the best does further test on another pig farm.
Experimental animal: select that age in days is close, the long X Dasanyuan of health that body weight is about 16 kg Du's X is mixed, and piglet is cooked experimental subjects.
Basal diet: need the mash feed coordinated with reference to NRC piglet nutrition.Add the Chinese herbal feed additive of embodiment 1-3 in daily ration as health care growth-promoting additive, additive capacity is 1000g/ ton feed.
Commercially available additive group is added by its description.
Method: weigh on an empty stomach before experiment, experiment terminates rear empty stomach and weighs.In serum, the concentration determination of anti-infective correlation factor IL-1, TNF-α is respectively in experiment 0 day, blood sampling in 30 days, 60 days, and separation of serum carries out experimental determination.(IL-1 detection kit, TNF-α detection kit are that U.S. TSZ produces)
Whole experiment totally 60 days, adopts free choice feeding, the way to manage of freely drinking water.Result of the test is in Table 2-4.
The Chinese herbal feed additive of table 2 embodiment 3 affects table to weaned piglets
| Group | Embodiment three | Commercially available additive | Control group |
| Before experiment heavy (kg) | 16.63±1.86 | 16.38±1.63 | 16.67±1.58 |
| Experiment terminates heavy (kg) | 58.75±1.56 | 53.66±1.44 | 53.11±1.52 |
| Average daily gain (g) | 702±15 b | 621±17 a | 607±14 a |
| Average daily ingestion amount (g) | 1622±45 | 1621±49 | 1609±54 |
| Feed-weight ratio | 2.31±0.03 b | 2.61±0.04 a | 2.65±0.01 a |
Note: the same shoulder of numeral in the ranks mark same letter represents group difference significantly (P>0.05), different letter representation group difference remarkable (P<0.05).Lower same
As can be seen from Table 2, the Chinese herbal feed additive of Application Example 3, makes an addition in piglet diet, can improve the production performance of pig, and average daily gain is significantly increased, and feed-weight ratio obviously reduces.
The Chinese herbal feed additive of table 3 embodiment 3 affects table to the anti-infective correlation factor IL-1 concentration of Swine serum
| Group | Embodiment 3 | Commercially available additive | Control group |
| 0 day (ng/ml) | 0.138±0.001 | 0.141±0.003 | 0.137±0.001 |
| 30 days (ng/ml) | 0.227±0.009 bc | 0.189±0.005 b | 0.129±0.006 a |
| 60 days (ng/ml) | 0.235±0.013 bc | 0.196±0.017 b | 0.104±0.021 a |
The Chinese herbal feed additive of table 4 embodiment 3 affects table to Swine serum anti-infective correlation factor TNF-α concentration
| Group | Embodiment 3 | Commercially available additive | Control group |
| 0 day (ng/ml) | 1.058±0.101 | 1.054±0.107 | 1.049±0.105 |
| 30 days (ng/ml) | ?1.465±0.109 bc | 1.289±0.115 b | 1.029±0.112 a |
| 60 days (ng/ml) | 1.635±0.113 bc | 1.396±0.117 b | 0.784±0.123 a |
As can be seen from table 3-4, the Chinese herbal feed additive of embodiment 3, to Swine serum anti-infective correlation factor IL-1 concentration with to Swine serum anti-infective correlation factor TNF-α concentration, was compared with contrast with commercially available additive, is had significant increase after 30 days, 60 days.
Thus, table 2-4 can find out, apply Chinese medicine additive of the present invention, make an addition in piglet diet, can improve the production performance of pig, average daily gain is significantly increased, and feed-weight ratio obviously reduces, and the incidence of disease of pig reduces greatly; Immunity of organisms and premunition can be improved simultaneously.Greatly reduce the incidence of disease in breeding process.
Although illustrate and describe embodiments of the invention above, be understandable that, above-described embodiment is exemplary, can not be interpreted as limitation of the present invention.
Claims (7)
1. a long Chinese herbal feed additive is urged in the health care for pig, it is characterized in that: formulated by the composition of following weight portion: cordate houttuynia 15-25 part, nauclea officinalis 10-20 part, large cool rattan 10-25 part, Radix Astragali 10-20 part, white crane rattan 12-26 part, loguat leaf 10-25 part, radix bupleuri 15-25 part, auricled hedyotis herb 15-25 part, gypsum 3-10 part.
2. Chinese herbal feed additive described in claim 1, is characterized in that: formulated by the composition of following weight portion: cordate houttuynia 25 parts, nauclea officinalis 20 parts, large 25 parts, cool rattan, the Radix Astragali 20 parts, 26 parts, white crane rattan, loguat leaf 25 parts, radix bupleuri 25 parts, auricled hedyotis herb 25 parts, 10 parts, gypsum.
3. Chinese herbal feed additive described in claim 1 or 2, is characterized in that: preparation method is, each composition is dried or dried to water content less than 10%; Take each composition dried: cordate houttuynia, nauclea officinalis, large cool rattan, the Radix Astragali, white crane rattan, loguat leaf, radix bupleuri, auricled hedyotis herb and gypsum, respectively or mixing ultramicro grinding cross more than 300 mesh sieves, stir packing and get final product.
4. the arbitrary described Chinese herbal feed additive of claim 1-3 is for raising the purposes of pig.
5. Chinese herbal feed additive described in claim 4 is for raising the purposes of pig, it is characterized in that, described purposes is short long for making pig keep healthy.
6. Chinese herbal feed additive described in claim 5 is for raising the purposes of pig, it is characterized in that, described purposes is to improve the production performance of pig, and average daily gain is significantly increased and immunity of organisms and premunition enhancing, in breeding process, the incidence of disease reduces.
7. the arbitrary described Chinese herbal feed additive of claim 4-6 is for raising the purposes of pig, it is characterized in that, the consumption of described Chinese herbal feed additive is 1000g/ ton daily ration.
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Cited By (1)
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Address after: Gold and stone Kim Po Road Xiangcheng Jinfeng Economic Development Zone, Fujian Province, Zhangzhou City Road area 363000 Applicant after: FUJIAN AONONG BIOTECHNOLOGY GROUP CO., LTD. Address before: Gold and stone Kim Po Road Xiangcheng Jinfeng Economic Development Zone, Fujian Province, Zhangzhou City Road area 363000 Applicant before: Fujian Ao Nong biotechnology Group Co.,Ltd |
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Application publication date: 20150114 |
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| RJ01 | Rejection of invention patent application after publication |