CN104258079A - Traditional Chinese medicine for treating chronic bronchitis - Google Patents

Traditional Chinese medicine for treating chronic bronchitis Download PDF

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Publication number
CN104258079A
CN104258079A CN201410541754.8A CN201410541754A CN104258079A CN 104258079 A CN104258079 A CN 104258079A CN 201410541754 A CN201410541754 A CN 201410541754A CN 104258079 A CN104258079 A CN 104258079A
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chronic bronchitis
chinese medicine
radix
treatment
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王银法
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/31Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/287Chrysanthemum, e.g. daisy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
    • A61K36/746Morinda
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/898Orchidaceae (Orchid family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/51Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/53Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

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  • Health & Medical Sciences (AREA)
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Abstract

The invention relates to a traditional Chinese medicine for treating the chronic bronchitis. The traditional Chinese medicine is prepared from bulk drugs in parts by weight as follows: 12 parts of whiteflowered bittercress roots, 16 parts of seremban, 7 parts of nepal pearleverlasting herb, 11 parts of fourstamen stephania roots, 6 parts of flos asteris souliei, 5 parts of common coltsfoot flowers and 23 parts of corymbose coelogyne pseudobulb. Clinical experiments prove that the traditional Chinese medicine can be used for treating the chronic bronchitis safely and effectively.

Description

A kind of Chinese medicine being used for the treatment of chronic bronchitis
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine being used for the treatment of chronic bronchitis.
Background technology
Chronic bronchitis is owing to infect or non-infective agent causes the chronic nonspecific inflammation of trachea-bronchial epithelial cell mucosa and surrounding tissue thereof.Its pathological characteristic is bronchus glandular hyperplasia, mucilage secretion increases.Clinically have continuous more than 2 years, the symptoms such as the cough often continuing more than three months, expectoration or asthma.Early symptom is slight, how to show effect in the winter time, alleviates after the spring is warm; Late phase inflammation increases the weight of, and symptom exists all the year round, regardless of season.Progression of disease again can concurrent obstructive emphysema, pulmonary heart disease, has a strong impact on labour force and health.Chronic bronchitis belongs to the category such as the traditional Chinese medical science " cough ", " the syndrome of dyspnea ", " phlegm retention ".Ancient Chinese medicine doctor all has more detailed record." Plain Questions " special train " coughing an opinion " section, proposes " vital organs of the human body all make us coughing, and non-only lung also ".Bright Zhang Jingyue proposes cough not from diseases caused by exogenous pathogenic factor, the saying of internal injury.Diseases caused by exogenous pathogenic factor are that six climate exopathogens violate lung, and internal injury is visceral dysfunction, send out as cough with asthma is for performance eventually with impairment of dispersing and descending function of the lung, abnormal rising of lung-QI.Weakened body resistance according to the domination of pathogen in treatment, control with eliminating evil cough-relieving, righting tonify deficiency.
Medical material present Research involved in the present invention is as follows:
Radix cardamines leucanthae [another name] Caulis et Folium Brassicae junceae, false Herba Apii graveolentis, Herba Incarvilleae sinensis, spend root stock or herb that stone Caulis et Folium Brassicae junceae [source] is crucifer Cardamine leucantha in vain.Autumn excavates, and removes earth impurity and fibrous root, dries.[habitats distribution] is distributed in the ground such as northeast, Shanxi, Shaanxi, Gansu, Jiangsu, Anhui, Zhejiang, Jiangxi, Henan, Hubei, Hunan, Sichuan.[nature and flavor] are pungent; Sweet; Flat [function cures mainly] preventing phlegm from forming and stopping coughing; Promoting blood circulation and stopping pain.Main pertussis; Chronic bronchitis; Have through uncomfortable; Traumatic injury.[usage and dosage] takes orally: decoct soup, 6-15g.[extracts] " China's book on Chinese herbal medicine "
Chinese mugwort [another name] Artemisia argyi Levl. et Van. var. argyi cv. Qiai in thousand, Coagulum Opuntiae sucus, Folium Crossostephii Chinensis, Bai Ai, white Folium Crossostephii Chinensis, beeweed, white Hibisci Mutabilis, Limonium wrightii Kuntz, rock head be [source] leaf that is feverfew Hibisci Mutabilis chrysanthemum in vain.The whole year all can adopt, and cleans, using fresh herb or dry.[nature and flavor] acrid in the mouth; Bitter; Slightly warm in nature.[function cures mainly] dispersing wind and cold; Reduce phlegm dampness removing; Removing toxic substances and promoting subsidence of swelling.Main anemofrigid cold; Cough with copious phlegm; Pertussis; Have loose bowels; Stranguria with turbid discharge; Leucorrhea; Carbuncle furunculosis.[usage and dosage] takes orally: decoct soup, 15-30g.External: appropriate, smashes deposited.[extracts] " China's book on Chinese herbal medicine "
Herba Anaphalidis Nepalensis [another name] fragrant blue or green [source] is the fragrant blue or green herb of feverfew Nepal.The 6-9 month gathers after spending, and cleans, dries.[nature and flavor] sweet in the mouth; Property is put down.[function cures mainly] heat clearing away suppressing the hyperactive liver; Relieving cough and relieving asthma.Main cold cough; Acute and chronic tracheitis; Prop up gas and asthma; Hypertension.[usage and dosage] takes orally: decoct soup, 3-12g.[extracts] " China's book on Chinese herbal medicine "
The root that large fruit bar halberd [another name] button lamp, Radix Stephaniae Tetrandrae, Vietnam's Herba Morindae Parvifoliae, Herba Paederiae Tomentosae [source] are the large fruit Radix Morindae Officinalis of Maguireothamnus speciosus.Autumn uproots, and cleans, dries.[nature and flavor] are pungent; Micro-hardship; Cool.[function cures mainly] expelling wind and removing dampness; Lung qi dispersing cough-relieving.Main air pain of dampness syndrome; Flu; Bronchitis; Upper respiratory tract infection.[usage and dosage] takes orally: decoct soup, 10-15g.[extracts] " China's book on Chinese herbal medicine "
Hide head inflorescence or root that Radix Asteris [another name] blue or green aster [source] this product is feverfew Aster souliei.5-7 to gather cephaloid the florescence month, dries in the shade; Spring, autumn uproot, and removing stem and leaf, cleans, dry.[nature and flavor] bitter in the mouth; Cold in nature.[function cures mainly] heat-clearing and toxic substances removing; Relieving cough and resolving phlegm.Main influenza; Tracheitis.[usage and dosage] takes orally: decoct soup, 3-9g; Or enter ball, loose.[extracts] " China's book on Chinese herbal medicine "
Flos Farfarae [another name] Flos Farfarae, money flower, see snuff, Ai Donghua, 99 flowers [sources] alabastrum that is feverfew coltsfoot.[nature and flavor] acrid in the mouth; Micro-sweet; Warm in nature.[return through] returns lung meridian.[function cures mainly] nourishing the lung to keep the adverse QI downward; Preventing phlegm from forming and stopping coughing.Main new chronic cough is coughed; Asthma; Chronic cough hemoptysis.[usage and dosage] takes orally: decoct soup, 3-10g; Or endure cream; Or enter ball, loose.External: appropriate, grinds into powder and dresses.[extracts] " China's book on Chinese herbal medicine "
Pseudobulbus Coelogynes corymbosae [another name] Shi Bajiao, be pseudobulb or the herb of orchid umbrella room Pseudobulbus Coelogynes corymbosae to leaf fruit, Herba Bulbophylli Odoratissim, hemostasis fruit, little green splendid achnatherum [source] this product.The whole year all can gather, and cleans, dries or using fresh herb after steaming.[nature and flavor] are pungent; Sweet; Cool.[return through] lung; Kidney channel.[function cures mainly] clearing and antitussive; Hemostasis analgesic therapy.Main bronchus is scorching; Flu; Fracture; Soft tissue contusion; Traumatic hemorrhage.[usage and dosage] takes orally: decoct soup, 15-30g.External: appropriate, fresh goods is smash deposited; Or dry product is ground into powder and is dressed.[extracts] " China's book on Chinese herbal medicine "
Summary of the invention
The present invention aims to provide a kind of Chinese medicine being used for the treatment of chronic bronchitis, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective healing chronic bronchitis.
In order to achieve the above object, the present invention is by the following technical solutions:
A kind of Chinese medicine being used for the treatment of chronic bronchitis, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Radix cardamines leucanthae 12 parts, Chinese mugwort in thousand 16 parts, Herba Anaphalidis Nepalensis 7 parts, large fruit bar halberd 11 parts, hide Radix Asteris 6 parts, Flos Farfarae 5 parts, Pseudobulbus Coelogynes corymbosae 23 parts.
Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:
1, physical data
Inventor in JIUYUE, 2011 ~ 2013 collect chronic bronchitis patient 70 example of outpatient clinic altogether between year April, all meet chronic bronchitis diagnostic criteria.Treatment group 35 example, matched group 35 example.Two groups of cases in sex, age, the course of disease and the state of an illness relatively in table 1.
A table 1 liang group patient basic condition compares
Two groups of patients compare P and are all greater than 0.05 in sex, age, the course of disease and the state of an illness as seen from the above table, have comparability.
2, test method
2.1 Therapeutic Method
The decoct that the oral the present invention for the treatment of group obtains according to specific embodiment 1, every day 3 times.4 weeks courses for the treatment of.
The oral levofloxacin of matched group (using according to its description), 4 weeks courses for the treatment of.
Clinical observation is coughed, pant, physical signs of lung and breathe hard, weak, xerostomia, sweating and the change of tongue arteries and veins.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect
With reference to " guideline of clinical investigations of new Chinese medicine treatment chronic bronchitis " of Ministry of Public Health formulation in 1999.
Recovery from illness: cough, expectorant, asthma shape disappear substantially, pulmonary's wheezing sound is slight person, observation index is improved to normal or is significantly improved;
Effective: cough, expectorant, asthma shape be clearly better, pulmonary's wheezing sound obviously alleviates, and observation index obviously improves;
Effective: cough, expectorant, asthma shape take a turn for the better, pulmonary's wheezing sound alleviates, observation index part improve;
Invalid: to cough, expectorant, asthma shape and pulmonary's wheezing sound without change, or alleviate not obvious, and symptom and wheezing sound add severe one, observation index is without improvement.
Effectively total=recovery from illness+effective+effectively.
3.2 therapeutic outcome
The comprehensive therapeutic effect of two groups compares in table 2.
A table 2 liang group comprehensive therapeutic effect compares
It is high and not easily recur that visible the present invention is used for the treatment of chronic bronchitis cure rate, has the value applied.
Detailed description of the invention
In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Specific embodiment 1
Take: Radix cardamines leucanthae 12 grams, Chinese mugwort in thousand 16 grams, Herba Anaphalidis Nepalensis 7 grams, large fruit bar halberd 11 grams, hide Radix Asteris 6 grams, Flos Farfarae 5 grams, Pseudobulbus Coelogynes corymbosae 23 grams; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 grams, must meet the decoct of adult normal's one day consumption.
Be used for the treatment of chronic bronchitis.Oral, every bu morning, noon and afternoon take for three times.
Specific embodiment 2
Take: Radix cardamines leucanthae 12 grams, Chinese mugwort in thousand 16 grams, Herba Anaphalidis Nepalensis 7 grams, large fruit bar halberd 11 grams, hide Radix Asteris 6 grams, Flos Farfarae 5 grams, Pseudobulbus Coelogynes corymbosae 23 grams; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, must meet the powder of adult normal's one day consumption.
Be used for the treatment of chronic bronchitis.Oral, every bu morning, noon and afternoon take for three times.
Specific embodiment 3
Take: Radix cardamines leucanthae 12 grams, Chinese mugwort in thousand 16 grams, Herba Anaphalidis Nepalensis 7 grams, large fruit bar halberd 11 grams, hide Radix Asteris 6 grams, Flos Farfarae 5 grams, Pseudobulbus Coelogynes corymbosae 23 grams; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, must meet the capsule of adult normal's one day consumption.
Be used for the treatment of chronic bronchitis.Oral, every bu morning, noon and afternoon take for three times.

Claims (4)

1. one kind is used for the treatment of the Chinese medicine of chronic bronchitis, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Radix cardamines leucanthae 12 parts, Chinese mugwort in thousand 16 parts, Herba Anaphalidis Nepalensis 7 parts, large fruit bar halberd 11 parts, hide Radix Asteris 6 parts, Flos Farfarae 5 parts, Pseudobulbus Coelogynes corymbosae 23 parts.
2. a kind of Chinese medicine being used for the treatment of chronic bronchitis as claimed in claim 1, it is characterized in that, its preparation method is: Radix cardamines leucanthae 12 parts, Chinese mugwort in thousand 16 parts, Herba Anaphalidis Nepalensis 7 parts, large fruit bar halberd 11 parts, hide Radix Asteris 6 parts, Flos Farfarae 5 parts, Pseudobulbus Coelogynes corymbosae 23 parts; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 parts, obtains decoct; Above-mentioned part all refers to weight portion.
3. a kind of Chinese medicine being used for the treatment of chronic bronchitis as claimed in claim 1, it is characterized in that, its preparation method is: take: Radix cardamines leucanthae 12 parts, Chinese mugwort in thousand 16 parts, Herba Anaphalidis Nepalensis 7 parts, large fruit bar halberd 11 parts, hide Radix Asteris 6 parts, Flos Farfarae 5 parts, Pseudobulbus Coelogynes corymbosae 23 parts; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, obtains powder; Above-mentioned part all refers to weight portion.
4. a kind of Chinese medicine being used for the treatment of chronic bronchitis as claimed in claim 1, it is characterized in that, its preparation method is: take: Radix cardamines leucanthae 12 parts, Chinese mugwort in thousand 16 parts, Herba Anaphalidis Nepalensis 7 parts, large fruit bar halberd 11 parts, hide Radix Asteris 6 parts, Flos Farfarae 5 parts, Pseudobulbus Coelogynes corymbosae 23 parts; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, obtains capsule; Above-mentioned part all refers to weight portion.
CN201410541754.8A 2014-10-12 2014-10-12 Traditional Chinese medicine for treating chronic bronchitis Pending CN104258079A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105708955A (en) * 2016-04-13 2016-06-29 刘海强 Medicine for treating chronic bronchitis

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
张思云等: "《食疗健身妙方》", 30 November 2013, 贵州科技出版社 *
杨毅勇: "慢性支气管炎中医辨证论治", 《同济大学学报(医学版)》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105708955A (en) * 2016-04-13 2016-06-29 刘海强 Medicine for treating chronic bronchitis

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Application publication date: 20150107