CN104257886A - Astringent preparation for deficiency of yin, hot blood and menorrhagia and preparation method thereof - Google Patents

Astringent preparation for deficiency of yin, hot blood and menorrhagia and preparation method thereof Download PDF

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CN104257886A
CN104257886A CN201410568111.2A CN201410568111A CN104257886A CN 104257886 A CN104257886 A CN 104257886A CN 201410568111 A CN201410568111 A CN 201410568111A CN 104257886 A CN104257886 A CN 104257886A
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herba
chinese medicine
parts
rhizoma
marmite
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陈济超
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Abstract

The invention discloses an astringent preparation for deficiency of yin, hot blood and menorrhagia, wherein the astringent preparation is prepared from the following main raw materials in parts by weight: 10-20 parts of Chinese wolfberry root-bark, 5-10 parts of rhizome of kirilow rhodiola, 12-25 parts of yerbadetajo herb, 6-15 parts of rustcoloured crotalaria herb with root, 5-9 parts of phellodendron bark, 8-14 parts of largehead atractylodes rhizome, 4-9 parts of lac, 6-9 parts of herb of tonkin pepper, 8-16 parts of charred sanguisorba root, 4-9 parts of licorice root and 7-12 parts of motherwort fruit. According to the invention, the astringent preparation for deficiency of yin, hot blood and menorrhagia is simple to operate, low in cost of medicinal materials, less in side effects and high in cure rate.

Description

Women's YinXuXueRe menorrhagia convergence astringent prescription and preparation method
Technical field
The invention discloses a kind of Chinese medicine preparation, relate to women's YinXuXueRe menorrhagia convergence astringent prescription and preparation method, belong to traditional Chinese medicine field.
Background technology
Menorrhagia refers to that in continuous several menstrual cycle, BTB amount is many, but menstruation interval and bleeding time are all regular, without the unexpected increase of intermenstrual bleeding, postcoital bleeding or menses, there is the class in ovulation type dysfunctional uterine bleeding in system, clinically with bleeding time and basal body temperature (BBT) curve control, ovulation type dysfunctional uterine bleeding will be had to be divided into menorrhagia and intermenstrual bleeding two class.Woman's menstrual blood volume number vary with each individual, be generally 20-100ml, more than 80ml or each three guarantees sanitary towel not enough and similar sanitary towel is all wet through and through, just belong to menorrhagia.Three kinds can be divided into, the deficiency of vital energy, heat in blood and blood stasis according to the reason of theory of Chinese medical science menorrhagia.The deficiency of vital energy causes deficiency of QI in middle-JIAO, the debility of CHONG and REN meridians, blood to lose and have under one's command; Heat in blood causes heat to be disturbed, and punching is appointed, the absurd row of forcing blood; Blood stasis causes stagnation of blood stasis in CHONG and REN meridians, escape of blood from meridian.
Publication No. CN 103784632 A(application number 201210423683.2) Chinese patent literature disclose for menorrheal compositions, include the raw material such as Radix et Caulis Opuntiae Dillenii fresh goods composition.Publication No. CN 102579695 A(application number 201210076985.7) Chinese patent literature disclose and a kind of decoction for the treatment of menoxenia, it is made up of the material of following weight proportioning: Flos Carthami 5-10 part, Cortex Phellodendri 5-15 part, Radix Rubiae 1-5 part, Radix Angelicae Dahuricae 3-8 part, Herba Leonuri 0.1-0.5 part, Herba Violae 3-10 part, Fructus Corni 5-10 part, Poria 3-8 part, Radix Angelicae Sinensis 5-10 part, Cortex Moutan 10-20 part and water 50-100 part.Publication No. CN 103893682 A(application number 201210588224.X) Chinese patent literature disclose a kind of Chinese medicine decoction for the treatment of menorrhagia, be made up of the material of following weight proportioning: Radix Angelicae Sinensis 12-14 gram, Semen Persicae 9-14 gram, Radix Curcumae 9-14 gram, Rhizoma Curcumae 8-12 gram, Olibanum 6-9 gram, Myrrha 6-9 gram, Rhizoma Chuanxiong 6-8 gram, Rhizoma Cyperi 12-14 gram, Radix Linderae 10-12 gram, Rhizoma Corydalis 10-12 gram, Radix Bupleuri 6-8 gram, Fructus Aurantii 10-12 gram, SHIXIAO SAN 25-30 gram.
At present for the medicament of menorrhagia caused by YinXuXueRe, on market, quantity also compares shortage, so for this symptom, also needs further R and D.
Summary of the invention
Not enough for prior art, the object of this invention is to provide and a kind ofly treat the many heat removing, blood cooling and hemorrhage arresting medicine agent of woman in menstrual period amount, there is feature simple to operate, evident in efficacy, and its adopts comparatively common Chinese crude drug with low cost, without financial burden.
Technical scheme of the present invention is:
Women's YinXuXueRe menorrhagia convergence astringent prescription, the main raw material(s) taking off row weight proportion is prepared from: Cortex Lycii 10-20; Rhizoma Rhodiolae kirilowii 5-10; Herba Ecliptae 12-25; Herba Crotalariae Ferrugineae 6-15; Cortex Phellodendri 5-9; Rhizoma Atractylodis Macrocephalae 8-14; Lacca 4-9; Herba Piperris Tonkinensis 6-9; Charred Radix Sanguisorbae 8-16; Radix Glycyrrhizae 4-9; Fructus Leonuri 7-12.
Preferably: Cortex Lycii 12-18; Rhizoma Rhodiolae kirilowii 6-9; Herba Ecliptae 15-22; Herba Crotalariae Ferrugineae 8-13; Cortex Phellodendri 6-8; Rhizoma Atractylodis Macrocephalae 10-12; Lacca 5-8; Herba Piperris Tonkinensis 7-8; Charred Radix Sanguisorbae 10-14; Radix Glycyrrhizae 5-8; Fructus Leonuri 8-11.
What be more preferably is: Cortex Lycii 15, Rhizoma Rhodiolae kirilowii 7.5, Herba Ecliptae 18.5, Herba Crotalariae Ferrugineae 10.5, Cortex Phellodendri 7, the Rhizoma Atractylodis Macrocephalae 11, Lacca 6.5, Herba Piperris Tonkinensis 7.5, charred Radix Sanguisorbae 12, Radix Glycyrrhizae 6.5, Fructus Leonuri 9.5.
Present invention also offers and this Chinese medicine preparation is made pharmaceutically acceptable granule, thick paste agent, pill and decoction.。
The preparation process of described granule is as follows:
1. get Cortex Lycii, Rhizoma Rhodiolae kirilowii, Herba Ecliptae clean remove impurity, mix thoroughly with saline, put into container and steam soft, cutting to smash into pureed to pieces for subsequent use;
2. Cortex Phellodendri, the Rhizoma Atractylodis Macrocephalae, Lacca, Herba Piperris Tonkinensis, charred Radix Sanguisorbae are cleaned and dried, put into mortar and be ground into end successively, cross 100-120 mesh sieve (preferably 110 orders);
3. get Fructus Leonuri to put into meter Shui Zhong and soak 1-2 hour (preferably 1.5 hours), after put into marmite big fire and stir-fry, until crack, leave standstill after cooling off and pulverized 110 mesh sieves;
4. Herba Crotalariae Ferrugineae, Radix Glycyrrhizae are put into marmite, add medical material weight 5-7 water (preferably 6 times) doubly, add step 1. 2. 3. gains after being heated to boiling, turn slow fire boiling 20-40 minute (preferably 30 minutes), filtered while hot medicinal liquid, is concentrated into 1/3 of original volume by medicine liquid heating;
5. adopt spray drying technology, the drying of gained concentrated solution, granulate, sterilizing, packaging are made the Chinese medicine granules of 3g/ bag.
The preparation method of described granule, step 3. middle meter Shui Liang was as the criterion there not to be medical material 1-2cm.
The preparation process of described thick paste agent is as follows:
1. get Cortex Lycii, Rhizoma Rhodiolae kirilowii, Herba Ecliptae clean remove impurity, mix thoroughly with saline, put into container and steam soft, cutting to smash into pureed to pieces for subsequent use;
2. Cortex Phellodendri, the Rhizoma Atractylodis Macrocephalae, Herba Piperris Tonkinensis, charred Radix Sanguisorbae are cleaned and dried, put into mortar and be ground into end successively, cross 100-120 mesh sieve (preferably 110 orders);
3. get Fructus Leonuri to put into meter Shui Zhong and soak 1-2 hour (preferably 1.5 hours), after put into marmite big fire and stir-fry, until crack, leave standstill after cooling off and pulverized 110 mesh sieves;
4. Herba Crotalariae Ferrugineae, Radix Glycyrrhizae are put into marmite, add medical material weight 5-7 water (preferably 6 times) doubly, step 1. 2. 3. gains are added after being heated to boiling, turn slow fire boiling 30 minutes, filter medicinal liquid, the Lacca that molten is clean while hot, under reduced pressure atmosphere, heating concentrates, stirs and make traditional Chinese medicine thick paste agent.
The preparation process of described pill is as follows:
1. Cortex Lycii, Rhizoma Rhodiolae kirilowii, Herba Ecliptae, Cortex Phellodendri, the Rhizoma Atractylodis Macrocephalae, Herba Piperris Tonkinensis, the clean saline of charred Radix Sanguisorbae are mixed thoroughly, run through, slow fire is dried, and puts into mortar and is ground into end successively, crosses 100-120 mesh sieve (preferably 110 orders);
2. get Fructus Leonuri to put into meter Shui Zhong and soak 1-2 hour (preferably 1.5 hours), after put into marmite big fire and stir-fry, until crack, leave standstill after cooling off and pulverized 110 mesh sieves;
3. Herba Crotalariae Ferrugineae, Radix Glycyrrhizae are put into marmite, add medical material weight 5-7 water (preferably 6 times) doubly, after being heated to boiling, add step 1. 2. gains, turn slow fire boiling 30 minutes, filter medicinal liquid, the Lacca that molten is clean while hot, heats concentrated medicament to 1/3 of original volume under reduced pressure atmosphere;
4. according to ratio mixed concentrated liquid and the refined honey of 3:1, under sterile working, medicine pill is made.
The preparation process of described decoction is as follows:
1. Cortex Phellodendri, the Rhizoma Atractylodis Macrocephalae, Lacca, Herba Piperris Tonkinensis, charred Radix Sanguisorbae are cleaned and dried, put into mortar and be ground into end successively, cross 100-120 mesh sieve (preferably 110 orders);
2. get Fructus Leonuri to put into meter Shui Zhong and soak 1-2 hour (preferably 1.5 hours), after put into marmite big fire and stir-fry, until crack, leave standstill after cooling off and pulverized 110 mesh sieves;
3. Cortex Lycii, Rhizoma Rhodiolae kirilowii, Herba Ecliptae shave are put into marmite, add medical material weight 5-7 water (preferably 6 times) doubly, be heated to boiling, then put into Herba Crotalariae Ferrugineae, Radix Glycyrrhizae, turn slow fire boiling 20-40 minute (preferably 30 minutes), filtered while hot medicinal liquid;
4. recrement adds water and continues to decoct, and moderate heat decocts 20-30 minute (preferably 25 minutes), and merge twice gained filtrate, mix above-mentioned gained filtrate and medicated powder, and stir, sterile packaged obtains Chinese medicine decoction.
Present invention also offers the application of described Chinese medicine preparation when preparing women's YinXuXueRe menorrhagia convergence astringent prescription.
The pharmacological effect of each crude drug is respectively:
Cortex Lycii: base is former: be the dry root bark of matrimony vine of solanaceae plant or lycium barbarum.Nature and flavor with return through: sweet, cold.Return lung, liver, kidney channel.Function with cure mainly: removing heat from blood except steaming, lung heat clearing pathogenic fire reducing.For deficiency of YIN hectic fever, hectic fever due to YIN-deficiency night sweat, cough due to lung-heat, spitting of blood, epistaxis, interior-heat is quenched one's thirst.
Rhizoma Rhodiolae kirilowii: base is former: be the root and rhizome of Crassulaceae Rhodida plant Rhodiola kirilowii (Regel) Maxim..Composition: herb is containing butyl alcohol, and daucosterol, rhodioside, hundred arteries and veins are with glycosides.The property of medicine: bitter, puckery, temperature.Return lung, the heart, liver, large intestine channel.Function cures mainly: tranquilizing by nourishing the heart, blood stasis dispelling, hemostasis.Cure mainly deficiency of vital energy and physically weak, weak palpitation and insomnia of losing heart, dizzy dizzy, pain uncomfortable in chest, traumatic injury, menoxenia, metrorrhagia, spits blood, dysentery, diarrhoea.Compatibility and incompatibility of drugs: " Shaanxi Chinese herbal medicine ": " anemia of pregnant woman prohibits clothes, excessive also removing blood stasis.”
Herba Ecliptae: base is former: be the dry aerial parts of feverfew Eclipta prostrata.Nature and flavor with return through: sweet, sour, cold.Return kidney, Liver Channel.Function with cure mainly: nourishing the liver and kidney, cooling blood for hemostasis.For the hepatic and renal YIN deficiency, odontoseisis, early whitening of beard and hair, dizzy ear toot, soreness of the waist and knees, YinXuXueRe haematemesis, epistaxis, hematuria, dysentery, metrostaxis, traumatic hemorrhage.
Herba Crotalariae Ferrugineae: base is former: for the false ground of pulse family Crotalaria plant is blue or the root of bar leaf Herba crotalariae mucronatae or herb.The property of medicine: bitter, micro-acid, flat.Return lung, liver, kidney channel.Function cures mainly: nourishing the liver and kidney, and cough-relieving is breathed heavily, and dampness removing cures mainly tinnitus, deaf, the vertigo, seminal emission, menorrhagia, leucorrhea, chronic cough expectorant blood, asthma, nephritis, dysuria, tonsillitis, parotitis, furuncle swelling toxin.
Cortex Phellodendri: nature and flavor with return through: bitter, cold.Return kidney, urinary bladder channel.Have heat clearing and damp drying, pathogenic fire purging removes steams, effect of detoxification sore treatment.For damp-heat dysentery, jaundice dark coloured urine, leukorrhagia pudendal pruritus, the puckery pain of pyretic stranguria, beriberi flaccidity is knitted, hectic fever due to YIN-deficiency consumptive fever, night sweat, seminal emission, sore swollen toxin, eczema eczema.
The Rhizoma Atractylodis Macrocephalae: nature and flavor with return through: bitter, sweet, temperature.Return spleen, stomach warp.Function with cure mainly: invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive.For insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.
Lacca: base is former: the dry colloid of secreting in the tree for Lacciferidae laccifer animal lac insect.Composition: between bar-shaped Lac resinous ten to percent 7 percent 80, between wax content six to percent seven percent, pigment four to percent eight percent.Lac resin can divide hard, soft two kinds, and animi resin accounts for 70 percent, and wherein pure lac resin accounts for 10 etc.The property of medicine: sweet, salty, flat.Function cures mainly: heat clearing away, removing heat from blood, removing toxic substances.Cure mainly measles, macule not saturating, menorrhagia, metrorrhagia, skin infection, eczema.Compatibility and incompatibility of drugs: anemia of pregnant woman is cautious use of.
Herba Piperris Tonkinensis: base is former: be the Herb of Piperaceae Piper plant optical axis ramie leaf Betel.Composition: aerial parts contains: sitosterol, 4-alkene-6-hydroxyl-3-stigmastane ketone, ergosterol peroxide, alkaloid: piperine, Piperyline, Guinea piperamide A, B etc.The property of medicine: Guangzhou army " conventional Chinese herbal medicine handbook ": " pungent, temperature." function cures mainly: expelling wind and cold, promoting blood flow to regulate menstruation, reducing swelling and alleviating pain.Cure mainly anemofrigid cold, rheumatic arthralgia, coldness and pain in the epigastrium, toothache, menoxenia, dysmenorrhea, treating swelling and pain by traumatic injury, snake bite and insect sting.
Radix Sanguisorbae: base is former: be the dry root of rosaceous plant Radix Sanguisorbae or the Radix Sanguisorbae that comes into leaves.Nature and flavor with return through: bitter, acid, puckery, be slightly cold.Return liver, large intestine channel.Function with cure mainly: cooling blood for hemostasis, removing toxic substances sore.For having blood in stool, hemorrhoidal bleeding, dysentery, metrorrhagia, burn due to hot liquid or fire, carbuncle sore tumefacting virus.Charred Radix Sanguisorbae: get pure land elm sheet, fries to surface coke black, inner sepia according to parch to black method.This product shape as Radix Sanguisorbae sheet, surface coke black, inner sepia.Tool burnt odor gas, mildly bitter flavor is puckery.
Radix Glycyrrhizae: sweet in the mouth, property is put down.There is QI invigorating invigorating middle warmer, relieving spasm to stop pain, effect of eliminating fire and detoxication, for the disease of laryngopharynx swelling and pain.
Fructus Leonuri: base is former: be the fruit of Labiatae mother wort plant Herba Leonuri and Herba Leonuri Sibirici.Composition: leonuri,fructus is containing alkaloid: leonurinine alkali, stachydrine, fatty oil, in oil, main component is oleic acid etc.Herb is containing phenolic glycoside class: A, B; Flavonoid glycoside: rutin, isoquercitrin, silver linden glycoside isorhamnetin-3-O-rutinoside.Iridoid glycosides.Herba Leonuri Sibirici fruit kind oil is containing allene class fatty acid: 7,8-eicosadienoic acid.The property of medicine: sweet, pungent, is slightly cold, mild toxicity.Return Liver Channel.Function cures mainly: promoting blood flow to regulate menstruation, liver heat removing and eyesight improving.Cure mainly menoxenia, dysmenorrhea, amenorrhea, the stagnant stomachache of the stasis of blood in puerperal; Liver-heat is had a headache, dizzy, conjunctival congestion and swelling pain, the raw cataracta of order.
Chinese medicine composition scientific formula provided by the invention, the preparation method of various dosage form is simple, products obtained therefrom taking convenience, and in addition, excellent results of the present invention also shows:
1, the present invention is through a large amount of theoretical researches and clinical experiment, and each dosage form therapeutic effect is remarkable;
2, Chinese crude drug selected by this prescription is Chinese medicine material, has no side effect, and Costco Wholesale is cheap;
3, the present invention is according to the principle of yin nourishing, heat clearing away, regulating menstruation, for this disease, has good opsonic action to health.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not by this restriction.
embodiment 1
Women's YinXuXueRe menorrhagia convergence astringent prescription, is prepared from by following bulk drugs: Cortex Lycii 10g, Rhizoma Rhodiolae kirilowii 5g, Herba Ecliptae 12g, Herba Crotalariae Ferrugineae 6g, Cortex Phellodendri 5g, Rhizoma Atractylodis Macrocephalae 8g, Lacca 4g, Herba Piperris Tonkinensis 6g, charred Radix Sanguisorbae 8g, Radix Glycyrrhizae 4g, Fructus Leonuri 7g.Above-mentioned treatment women YinXuXueRe menorrhagia restrains the preparation method of astringent or styptic treatment for spontaneous sweating Chinese medicine granules:
1. get Cortex Lycii, Rhizoma Rhodiolae kirilowii, Herba Ecliptae clean remove impurity, mix thoroughly with saline, put into container and steam soft, cutting to smash into pureed to pieces for subsequent use;
2. Cortex Phellodendri, the Rhizoma Atractylodis Macrocephalae, Lacca, Herba Piperris Tonkinensis, charred Radix Sanguisorbae are cleaned and dried, put into mortar and be ground into end successively, cross 100 mesh sieves;
3. get Fructus Leonuri and put into meter Shui Zhong, do not have medical material 1-2cm, soak 1 hour, after put into marmite big fire and stir-fry, until crack, leave standstill after cooling off and pulverized 110 mesh sieves;
4. Herba Crotalariae Ferrugineae, Radix Glycyrrhizae are put into marmite, add the water of medical material weight 5 times, add step 1. 2. 3. gains after being heated to boiling, turn slow fire boiling 20 minutes, filtered while hot medicinal liquid, medicine liquid heating is concentrated into 1/3 of original volume;
5. adopt spray drying technology, the drying of gained concentrated solution, granulate, sterilizing, packaging are made the Chinese medicine granules of 3g/ bag.
embodiment 2
Women's YinXuXueRe menorrhagia convergence astringent prescription, is prepared from by following bulk drugs: Cortex Lycii 20g, Rhizoma Rhodiolae kirilowii 10g, Herba Ecliptae 25g, Herba Crotalariae Ferrugineae 15g, Cortex Phellodendri 9g, Rhizoma Atractylodis Macrocephalae 14g, Lacca 9g, Herba Piperris Tonkinensis 9g, charred Radix Sanguisorbae 16g, Radix Glycyrrhizae 9g, Fructus Leonuri 12g.Above-mentioned treatment women YinXuXueRe menorrhagia restrains the preparation method of astringent or styptic treatment for spontaneous sweating traditional Chinese medicine thick paste agent:
1. get Cortex Lycii, Rhizoma Rhodiolae kirilowii, Herba Ecliptae clean remove impurity, mix thoroughly with saline, put into container and steam soft, cutting to smash into pureed to pieces for subsequent use;
2. Cortex Phellodendri, the Rhizoma Atractylodis Macrocephalae, Herba Piperris Tonkinensis, charred Radix Sanguisorbae are cleaned and dried, put into mortar and be ground into end successively, cross 110 mesh sieves;
3. get Fructus Leonuri to put into meter Shui Zhong and soak 1.5 hours, after put into marmite big fire and stir-fry, until crack, leave standstill after cooling off and pulverized 110 mesh sieves;
4. Herba Crotalariae Ferrugineae, Radix Glycyrrhizae are put into marmite, add the water of medical material weight 6 times, after being heated to boiling, add step 1. 2. 3. gains, turn slow fire boiling 30 minutes, filter medicinal liquid, the Lacca that molten is clean while hot, under reduced pressure atmosphere, heating concentrates, stirs and make traditional Chinese medicine thick paste agent.
Instructions of taking: get two soup ladles and be as the criterion (about 30-40 milliliter), boiled water is taken after melting, and every day three times 6 days is a course for the treatment of.
Model case: xxx, the age: 36 years old; Sex: female; Medical history: patient occurs menorrhagia in continuous three months, with symptoms such as feverish sensation in the palms and soles, dry pharynx dryness of the tongue, is YinXuXueRe type menorrhagia through tcm diagnosis.
Take the agent of this example gained traditional Chinese medicine thick paste, after the course for the treatment of, symptom is obviously alleviated, and continues three courses for the treatment of of use, and patient menstrual measures and recovers normal, without recurrent exerbation.
embodiment 3
Women's YinXuXueRe menorrhagia convergence astringent prescription, is prepared from by following bulk drugs: Cortex Lycii 12g, Rhizoma Rhodiolae kirilowii 6g, Herba Ecliptae 15g, Herba Crotalariae Ferrugineae 8g, Cortex Phellodendri 6g, Rhizoma Atractylodis Macrocephalae 10g, Lacca 5g, Herba Piperris Tonkinensis 7g, charred Radix Sanguisorbae 10g, Radix Glycyrrhizae 5g, Fructus Leonuri 8g.Above-mentioned treatment women YinXuXueRe menorrhagia restrains the preparation method of astringent or styptic treatment for spontaneous sweating medicine pill:
1. Cortex Lycii, Rhizoma Rhodiolae kirilowii, Herba Ecliptae, Cortex Phellodendri, the Rhizoma Atractylodis Macrocephalae, Herba Piperris Tonkinensis, the clean saline of charred Radix Sanguisorbae are mixed thoroughly, run through, slow fire is dried, and puts into mortar and is ground into end successively, crosses 110 mesh sieves;
2. get Fructus Leonuri to put into meter Shui Zhong and soak 1.5 hours, after put into marmite big fire and stir-fry, until crack, leave standstill after cooling off and pulverized 110 mesh sieves;
3. Herba Crotalariae Ferrugineae, Radix Glycyrrhizae are put into marmite, add the water of medical material weight 6 times, after being heated to boiling, add step 1. 2. gains, turn slow fire boiling 30 minutes, filter medicinal liquid, the Lacca that molten is clean while hot, heats concentrated medicament to 1/3 of original volume under reduced pressure atmosphere;
4. according to ratio mixed concentrated liquid and the refined honey of 3:1, under sterile working, medicine pill is made.
Instructions of taking: each two, every day three times, warm boiled water 6 days is a course for the treatment of.
Model case: xxx, the age: 44 years old; Sex: female; Medical history: patient occurred menoxenia before half a year, menorrhagia, matter are thick, and with symptoms such as hectically flushed cheeks, red tongue, tongue are few, tcm diagnosis is YinXuXueRe type menorrhagia.
Take this example gained medicine pill, after the course for the treatment of of patient, symptom alleviates, and the mental status improves, and continue three courses for the treatment of of use, menstrual blood volume returns to normally, consolidates and fully recovers afterwards for one week.
embodiment 4
Women's YinXuXueRe menorrhagia convergence astringent prescription, is prepared from by following bulk drugs: Cortex Lycii 18g, Rhizoma Rhodiolae kirilowii 9g, Herba Ecliptae 22g, Herba Crotalariae Ferrugineae 13g, Cortex Phellodendri 8g, Rhizoma Atractylodis Macrocephalae 12g, Lacca 8g, Herba Piperris Tonkinensis 8g, charred Radix Sanguisorbae 14g, Radix Glycyrrhizae 8g, Fructus Leonuri 11g.Above-mentioned treatment women YinXuXueRe menorrhagia restrains the preparation method of astringent or styptic treatment for spontaneous sweating Chinese medicine decoction:
1. Cortex Phellodendri, the Rhizoma Atractylodis Macrocephalae, Lacca, Herba Piperris Tonkinensis, charred Radix Sanguisorbae are cleaned and dried, put into mortar and be ground into end successively, cross 110 mesh sieves;
2. get Fructus Leonuri to put into meter Shui Zhong and soak 1.5 hours, after put into marmite big fire and stir-fry, until crack, leave standstill after cooling off and pulverized 110 mesh sieves;
3. Cortex Lycii, Rhizoma Rhodiolae kirilowii, Herba Ecliptae shave are put into marmite, add the water of medical material weight 6 times, be heated to boiling, then put into Herba Crotalariae Ferrugineae, Radix Glycyrrhizae, turn slow fire boiling 30 minutes, filtered while hot medicinal liquid;
4. recrement adds water and continues to decoct, and moderate heat decocts 25 minutes, merges twice gained filtrate, and mix above-mentioned gained filtrate and medicated powder, and stir, sterile packaged obtains Chinese medicine decoction.
Instructions of taking: twice daily, a 150-200ml 6 days is a course for the treatment of.
Model case: xxx, the age: 27 years old; Sex: female; Medical history: patient once stayed up late for a long time, the rear phenomenon occurring menorrhagia, and the symptom such as have feverish sensation in the palms and soles, dry mouth and throat, red tongue, tongue few, be diagnosed as YinXuXueRe type menorrhagia.
Take this example gained Chinese medicine decoction, after two courses for the treatment of of patient, menstrual blood volume comparatively before obviously reduce, uncomfortable disease alleviates, and continue two courses for the treatment of of use, the eumenorrhea, health is fully recovered.
embodiment 5
Women's YinXuXueRe menorrhagia convergence astringent prescription, is prepared from by following bulk drugs: Cortex Lycii 15g, Rhizoma Rhodiolae kirilowii 7.5g, Herba Ecliptae 18.5g, Herba Crotalariae Ferrugineae 10.5g, Cortex Phellodendri 7g, Rhizoma Atractylodis Macrocephalae 11g, Lacca 6.5g, Herba Piperris Tonkinensis 7.5g, charred Radix Sanguisorbae 12g, Radix Glycyrrhizae 6.5g, Fructus Leonuri 9.5g.Above-mentioned treatment women YinXuXueRe menorrhagia restrains the preparation method of astringent or styptic treatment for spontaneous sweating Chinese medicine granules:
1. get Cortex Lycii, Rhizoma Rhodiolae kirilowii, Herba Ecliptae clean remove impurity, mix thoroughly with saline, put into container and steam soft, cutting to smash into pureed to pieces for subsequent use;
2. Cortex Phellodendri, the Rhizoma Atractylodis Macrocephalae, Lacca, Herba Piperris Tonkinensis, charred Radix Sanguisorbae are cleaned and dried, put into mortar and be ground into end successively, cross 110 mesh sieves;
3. get Fructus Leonuri to put into meter Shui Zhong and do not have medical material 1-2cm, soak 1.5 hours, after put into marmite big fire and stir-fry, until crack, leave standstill after cooling off and pulverized 110 mesh sieves;
4. Herba Crotalariae Ferrugineae, Radix Glycyrrhizae are put into marmite, add the water of medical material weight 6 times, add step 1. 2. 3. gains after being heated to boiling, turn slow fire boiling 30 minutes, filtered while hot medicinal liquid, medicine liquid heating is concentrated into 1/3 of original volume;
5. adopt spray drying technology, the drying of gained concentrated solution, granulate, sterilizing, packaging are made the Chinese medicine granules of 3g/ bag.
Instructions of taking: every day three times, once a bag, warm boiled water six days is a course for the treatment of.
test example 1embodiment 5 gained women YinXuXueRe menorrhagia restrains the clinical practice of astringent or styptic treatment for spontaneous sweating Chinese medicine granules:
Choose crowd: choose YinXuXueRe according to clinic case and cause the women 306 of menorrhagia routine, be randomly assigned to two groups according to disease, experimental group and matched group.Wherein experimental group 180 people, age 20-55 year; Matched group 126 people, age 20-55 year.
Diagnostic criteria: 1. fully recover: menstrual blood volume returns to normally, without other uncomfortable diseases; 2. effective: menstrual blood volume slightly controls, uncomfortable disease alleviates; 3. invalid: menstrual blood volume is unchanged, uncomfortable disease exists.
Test method: experimental group takes example five gained Chinese medicine granules, every day three times, once a bag, warm boiled water seven days is a course for the treatment of; Matched group takes other conventional medicines (as LIUWEI DIHUANG WAN, ease pill, Herba Leonuri granule, hemorrhage etc.).
Therapeutic effect: total effective rate=cure rate+obvious effective rate.
Through the treatment of four courses for the treatment of (24 days), the effect of experimental group and matched group is respectively: experimental group: fully recover 80.5%(145), effective 17.8%(32), invalid 1.7%(3), total effective rate 98.3%, matched group: fully recover 69.0 %(87), effective 12.7%(16), invalid 18.3%(23), total effective rate 81.7%, the total effective rate of experimental group is apparently higher than matched group as can be seen here.
Selected medical material in Chinese medicine preparation of the present invention has effect of nourishing liver and kidney, cooling blood for hemostasis, QI invigorating invigorating middle warmer, for women's YinXuXueRe menorrhagia, can reach the effect that convergence is astringent or styptic treatment for spontaneous sweating.Through clinical trial certificate, take Chinese medicine preparation of the present invention, it is fast that patient not only cures speed, no longer recurs more, and the conditioning comparatively conventional medicine also Be very effective to health before and after treatment, can be widely used in clinical treatment.
It should be pointed out that detailed description of the invention is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, within the spirit and principles in the present invention all, any amendment, replacement, improvement etc. done, all should be included within protection scope of the present invention.

Claims (10)

1. women's YinXuXueRe menorrhagia convergence astringent prescription, it is characterized in that, the main raw material(s) taking off row weight proportion is prepared from: Cortex Lycii 10-20; Rhizoma Rhodiolae kirilowii 5-10; Herba Ecliptae 12-25; Herba Crotalariae Ferrugineae 6-15; Cortex Phellodendri 5-9; Rhizoma Atractylodis Macrocephalae 8-14; Lacca 4-9; Herba Piperris Tonkinensis 6-9; Charred Radix Sanguisorbae 8-16; Radix Glycyrrhizae 4-9; Fructus Leonuri 7-12.
2. Chinese medicine preparation as claimed in claim 1, it is characterized in that, the main raw material(s) taking off row weight proportion is prepared from: Cortex Lycii 12-18; Rhizoma Rhodiolae kirilowii 6-9; Herba Ecliptae 15-22; Herba Crotalariae Ferrugineae 8-13; Cortex Phellodendri 6-8; Rhizoma Atractylodis Macrocephalae 10-12; Lacca 5-8; Herba Piperris Tonkinensis 7-8; Charred Radix Sanguisorbae 10-14; Radix Glycyrrhizae 5-8; Fructus Leonuri 8-11.
3. Chinese medicine preparation as claimed in claim 1, it is characterized in that, the main raw material(s) taking off row weight proportion is prepared from: Cortex Lycii 15, Rhizoma Rhodiolae kirilowii 7.5, Herba Ecliptae 18.5, Herba Crotalariae Ferrugineae 10.5, Cortex Phellodendri 7, the Rhizoma Atractylodis Macrocephalae 11, Lacca 6.5, Herba Piperris Tonkinensis 7.5, charred Radix Sanguisorbae 12, Radix Glycyrrhizae 6.5, Fructus Leonuri 9.5.
4. the Chinese medicine preparation as described in as arbitrary in claim 1-3, is characterized in that, this Chinese medicine preparation is made pharmaceutically acceptable granule, thick paste agent, pill and decoction.
5. arbitrary described Chinese medicine preparation in claim 4, it is characterized in that, the preparation process of described granule is as follows:
1. get Cortex Lycii, Rhizoma Rhodiolae kirilowii, Herba Ecliptae clean remove impurity, mix thoroughly with saline, put into container and steam soft, cutting to smash into pureed to pieces for subsequent use;
2. Cortex Phellodendri, the Rhizoma Atractylodis Macrocephalae, Lacca, Herba Piperris Tonkinensis, charred Radix Sanguisorbae are cleaned and dried, put into mortar and be ground into end successively, cross 100-120 mesh sieve (preferably 110 orders);
3. get Fructus Leonuri to put into meter Shui Zhong and soak 1-2 hour (preferably 1.5 hours), after put into marmite big fire and stir-fry, until crack, leave standstill after cooling off and pulverized 110 mesh sieves;
4. Herba Crotalariae Ferrugineae, Radix Glycyrrhizae are put into marmite, add medical material weight 5-7 water (preferably 6 times) doubly, add step 1. 2. 3. gains after being heated to boiling, turn slow fire boiling 20-40 minute (preferably 30 minutes), filtered while hot medicinal liquid, is concentrated into 1/3 of original volume by medicine liquid heating;
5. adopt spray drying technology, the drying of gained concentrated solution, granulate, sterilizing, packaging are made the Chinese medicine granules of 3g/ bag.
6. Chinese medicine preparation as claimed in claim 5, is characterized in that, described step 3. middle meter Shui Liang was as the criterion there not to be medical material 1-2cm.
7. Chinese medicine preparation as claimed in claim 4, it is characterized in that, the preparation process of described thick paste agent is as follows:
1. get Cortex Lycii, Rhizoma Rhodiolae kirilowii, Herba Ecliptae clean remove impurity, mix thoroughly with saline, put into container and steam soft, cutting to smash into pureed to pieces for subsequent use;
2. Cortex Phellodendri, the Rhizoma Atractylodis Macrocephalae, Herba Piperris Tonkinensis, charred Radix Sanguisorbae are cleaned and dried, put into mortar and be ground into end successively, cross 100-120 mesh sieve (preferably 110 orders);
3. get Fructus Leonuri to put into meter Shui Zhong and soak 1-2 hour (preferably 1.5 hours), after put into marmite big fire and stir-fry, until crack, leave standstill after cooling off and pulverized 110 mesh sieves;
4. Herba Crotalariae Ferrugineae, Radix Glycyrrhizae are put into marmite, add medical material weight 5-7 water (preferably 6 times) doubly, step 1. 2. 3. gains are added after being heated to boiling, turn slow fire boiling 30 minutes, filter medicinal liquid, the Lacca that molten is clean while hot, under reduced pressure atmosphere, heating concentrates, stirs and make traditional Chinese medicine thick paste agent.
8. Chinese medicine preparation as claimed in claim 4, it is characterized in that, the preparation process of described pill is as follows:
1. Cortex Lycii, Rhizoma Rhodiolae kirilowii, Herba Ecliptae, Cortex Phellodendri, the Rhizoma Atractylodis Macrocephalae, Herba Piperris Tonkinensis, the clean saline of charred Radix Sanguisorbae are mixed thoroughly, run through, slow fire is dried, and puts into mortar and is ground into end successively, crosses 100-120 mesh sieve (preferably 110 orders);
2. get Fructus Leonuri to put into meter Shui Zhong and soak 1-2 hour (preferably 1.5 hours), after put into marmite big fire and stir-fry, until crack, leave standstill after cooling off and pulverized 110 mesh sieves;
3. Herba Crotalariae Ferrugineae, Radix Glycyrrhizae are put into marmite, add medical material weight 5-7 water (preferably 6 times) doubly, after being heated to boiling, add step 1. 2. gains, turn slow fire boiling 30 minutes, filter medicinal liquid, the Lacca that molten is clean while hot, heats concentrated medicament to 1/3 of original volume under reduced pressure atmosphere;
4. according to ratio mixed concentrated liquid and the refined honey of 3:1, under sterile working, medicine pill is made.
9. Chinese medicine preparation as claimed in claim 4, it is characterized in that, the preparation process of described decoction is as follows:
1. Cortex Phellodendri, the Rhizoma Atractylodis Macrocephalae, Lacca, Herba Piperris Tonkinensis, charred Radix Sanguisorbae are cleaned and dried, put into mortar and be ground into end successively, cross 100-120 mesh sieve (preferably 110 orders);
2. get Fructus Leonuri to put into meter Shui Zhong and soak 1-2 hour (preferably 1.5 hours), after put into marmite big fire and stir-fry, until crack, leave standstill after cooling off and pulverized 110 mesh sieves;
3. Cortex Lycii, Rhizoma Rhodiolae kirilowii, Herba Ecliptae shave are put into marmite, add medical material weight 5-7 water (preferably 6 times) doubly, be heated to boiling, then put into Herba Crotalariae Ferrugineae, Radix Glycyrrhizae, turn slow fire boiling 20-40 minute (preferably 30 minutes), filtered while hot medicinal liquid;
4. recrement adds water and continues to decoct, and moderate heat decocts 20-30 minute (preferably 25 minutes), and merge twice gained filtrate, mix above-mentioned gained filtrate and medicated powder, and stir, sterile packaged obtains Chinese medicine decoction.
10. the application of the Chinese medicine preparation as described in as arbitrary in claim 1-3 when preparing women's YinXuXueRe menorrhagia convergence astringent prescription.
CN201410568111.2A 2014-10-23 2014-10-23 Astringent preparation for deficiency of yin, hot blood and menorrhagia and preparation method thereof Pending CN104257886A (en)

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Publication number Priority date Publication date Assignee Title
CN1565556A (en) * 2003-06-18 2005-01-19 薛永新 Chinese drugs for treating preceded menstrual cycle and excessive menses due to blood heat
CN103784756A (en) * 2014-02-20 2014-05-14 丁常燕 Traditional Chinese medicine composition for treating internal heat due to yin deficiency

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1565556A (en) * 2003-06-18 2005-01-19 薛永新 Chinese drugs for treating preceded menstrual cycle and excessive menses due to blood heat
CN103784756A (en) * 2014-02-20 2014-05-14 丁常燕 Traditional Chinese medicine composition for treating internal heat due to yin deficiency

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Application publication date: 20150107