CN104189518A - Medicine for sterilizing and delousing captive animals - Google Patents
Medicine for sterilizing and delousing captive animals Download PDFInfo
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- CN104189518A CN104189518A CN201410368788.1A CN201410368788A CN104189518A CN 104189518 A CN104189518 A CN 104189518A CN 201410368788 A CN201410368788 A CN 201410368788A CN 104189518 A CN104189518 A CN 104189518A
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Abstract
The invention provides a medicine for sterilizing and delousing captive animals. The medicine is prepared from the following components: 50-80g of aconite, 50-80g of melia azedarach L, 50-80g of litsea cubeba, 30-50g of radix phytolaccae, 30-50g of Chinese pulsatilla root, 30-50g of cassia bark, 30-50g of Siberian cocklebur fruit, 30-50g of barbated skullcup herb, 30-50g of officinal magnolia bark, 10-25g of tall gastrodia tuber, 10-25g of rhizoma polygonati, 10-25g of garlic, 3-5g of alum and 3-5g of mirabilite. The medicine is simple in proportioning, is convenient to use and has good antibacterial effects and obvious delousing effects.
Description
technical field:
The present invention relates to technical field of pharmaceuticals, relate in particular to a kind of captive animal sterilization delousing medication thing.
background technology:
At present, the cultivation of animal is still taking stable breeding as main, as cowboying, raise pigs etc., the animal wastes of stable breeding are overstock in circle, are easy to breed bacteria, and animal lies prone sleeping for a long time, easily grow the parasites such as louse, pathogenic bacteria has increased the ill probability of animal greatly, and parasite causes animal skin pruritus, uneasy in either sitting or lying, can not keep long-time complete sleep, impact is got fat.For example.The weight growth of the clean colony house of washing every day and the every three days colony houses that only excrement is not washed clearly compares, and finds, clean aseptic colony house is early delivered 7-10 days for sale dirty colony house.The ill probability 8-12 percentage point that can decline.But overstocked feces has just been rinsed in washing, accomplish cage house floor cleaning, and cannot sterilizing or kill parasite, in fact, antibacterial or parasite are larger on the impact of animal.For animal colony house conventional have a disinfectant etc., also there is end user to carry out sterilizing delousing with medicine, in prior art, Chinese patent application 8,910 3338.6 discloses a kind of sterilization, delousing shampoo, its main delousing composition is any or several in the Radix Stemonae, group planting perfume (or spice), Flos Caryophylli, Fructus Cnidii, Li Lu, Radix seu Caulis Derridis Trifoliatae, peppery Miao, Flos Rhododendri Mollis, for another example, it is that antibacterial parasite killing delousing kills the antipruritic easypro skin tincture of demodicid mite that Chinese patent application 201210237575.6 discloses a kind of nanometer silver, and hundred step 100-140g account for 18.5-25.9%; Sulfur 40-80g accounts for 7.4-14.8%; Fructus Carpesii, Radix Sophorae Flavescentis, Cortex Dictamni, the Fructus Kochiae, Galla Chinensis, Fructus Cnidii, Liu Jishuan, Radix Et Rhizoma Rhei, the each 20-60g of sulfur zinc respectively account for 3.7-11.1%.For another example, Chinese patent application 20,121,053 09313 discloses a kind of Chinese medicine for the treatment of enterobiasis, Rhizoma Fagopyri Dibotryis 13-17, Rhizoma Smilacis Glabrae 10-14, Galla Chinensis 13-17, Fructus Cnidii 6, Fructus Rosae Laevigatae 6, Corium Erinacei Seu Hemiechianus 10-14, Herba Plantaginis 1-5, Herba Salviae Chinensis 13-17, Pseudobulbus Bletillae (Rhizoma Bletillae) 10-14, Folium Artemisiae Argyi 1-5, Radix Notoginseng 6, Radix Stemonae 13-17, Bulbus Allii 10-14, Pericarpium Granati 6, bog moss 10-14.And for example, Chinese patent application 2013106950592 discloses one and has treated dermopathic medicine and preparation, Radix Cynanchi Atrati 20-30g, Aloe 15-35g, Cortex Meliae 30-50g, Alumen 30-50g, Spina Gleditsiae 30-40g, Fructus Bruceae 10-20g, Rhizoma Zingiberis Recens 20-40g, Pericarpium Zanthoxyli 20-30g, Folium Perillae 20-35g, Radix Angelicae Dahuricae 25-40g, Fructus Xanthii 30-40g, Herba Menthae 20-30g, Cortex Phellodendri 35-50g, Radix Sophorae Flavescentis 40-60g, Radix Arnebiae (Radix Lithospermi) 25-35g, Caulis Sargentodoxae 30-50g, Cortex Dictamni 50-70g, Cortex Lycii 30-50g, Radix Cynanchi Paniculati 30-45g, Fructus Kochiae 60-80g, Fructus Cnidii 60-80g, Flos Carthami 30-40g, Fructus Atriplicis Sibiricae 30-40g, Flos Chrysanthemi Indici 40-50g, Radix Stemonae 40-50g, Fructus Psoraleae 40-50g, Flos Caryophylli 30-40g.The present invention on the basis of existing technology, aims to provide a kind of proportioning simple, easy to use, and good antimicrobial effect has a kind of captive animal sterilization delousing medication thing of obvious cootie killing effect.
summary of the invention:
The object of the invention is to overcome the shortcoming existing in prior art, provide a kind of proportioning simple, easy to use, good antimicrobial effect, has a kind of captive animal sterilization delousing medication thing of obvious cootie killing effect.
To achieve these goals, the invention provides a kind of captive animal sterilization delousing medication thing, wherein, according to following component preparation, Aconitum carmichjaelii Debx., Fructus Toosendan, the each 50-80g of Fructus Litseae, Radix Phytolaccae, the Radix Pulsatillae, Cortex Cinnamomi, Fructus Xanthii, Herba Scutellariae Barbatae, the each 30-50g of Cortex Magnoliae Officinalis, Rhizoma Gastrodiae, Rhizoma Polygonati, the each 10-25g of Bulbus Allii, Alumen, Natrii Sulfas 3-5g.
Or, according to following component preparation, Aconitum carmichjaelii Debx., Fructus Toosendan, the each 50-70g of Fructus Litseae, Radix Phytolaccae, the Radix Pulsatillae, Cortex Cinnamomi, Fructus Xanthii, Herba Scutellariae Barbatae, the each 30-40g of Cortex Magnoliae Officinalis, Rhizoma Gastrodiae, Rhizoma Polygonati, the each 10-20g of Bulbus Allii, Alumen, Natrii Sulfas 3-4g.
Or, according to following component preparation, Aconitum carmichjaelii Debx., Fructus Toosendan, the each 60-80g of Fructus Litseae, Radix Phytolaccae, the Radix Pulsatillae, Cortex Cinnamomi, Fructus Xanthii, Herba Scutellariae Barbatae, the each 40-50g of Cortex Magnoliae Officinalis, Rhizoma Gastrodiae, Rhizoma Polygonati, the each 15-25g of Bulbus Allii, Alumen, Natrii Sulfas 4-5g.
Or, according to following component preparation, Aconitum carmichjaelii Debx., Fructus Toosendan, the each 55-75g of Fructus Litseae, Radix Phytolaccae, the Radix Pulsatillae, Cortex Cinnamomi, Fructus Xanthii, Herba Scutellariae Barbatae, the each 35-45g of Cortex Magnoliae Officinalis, Rhizoma Gastrodiae, Rhizoma Polygonati, the each 18-22g of Bulbus Allii, Alumen, Natrii Sulfas 3.5-4.5g.
The preparation method of captive animal sterilization delousing medication thing, by Aconitum carmichjaelii Debx., Fructus Toosendan, Fructus Litseae, Radix Phytolaccae, the Radix Pulsatillae, Cortex Cinnamomi, Fructus Xanthii, Herba Scutellariae Barbatae, Cortex Magnoliae Officinalis, Rhizoma Gastrodiae, Rhizoma Polygonati, Bulbus Allii, the lixiviate of use water extract method three times, after three times lixiviating solution merges, add Natrii Sulfas, steaming and decocting, to the thick Alumen that adds, is powder after being dried.
After being dried to powder, the 80-120 order that sieves, after sieve, gains, through the ultra-vioket radiation 15S that sterilizes, obtain captive animal sterilization delousing medication thing of the present invention.
Advantage of the present invention is: proportioning is simple, easy to use, good antimicrobial effect, there is obvious cootie killing effect, the present invention is taking Aconitum carmichjaelii Debx., Fructus Toosendan, Fructus Litseae as monarch drug, Radix Phytolaccae, the Radix Pulsatillae, Cortex Cinnamomi, Fructus Xanthii, Herba Scutellariae Barbatae, Cortex Magnoliae Officinalis are ministerial drug, and Rhizoma Gastrodiae, Rhizoma Polygonati, Bulbus Allii, Alumen are adjuvant drug, and Natrii Sulfas is for making medicine.Total alkaloid content of the present invention is higher than 2.0%, and biological general glycoside is greater than 1.5%, and the pet cat of louse, fungal infection, Canis familiaris L. amount to 86 routine effect comparisons, effective percentage 91.5%.
detailed description of the invention:
Captive animal sterilization delousing medication thing, wherein, according to following component preparation, Aconitum carmichjaelii Debx., Fructus Toosendan, the each 50-80g of Fructus Litseae, Radix Phytolaccae, the Radix Pulsatillae, Cortex Cinnamomi, Fructus Xanthii, Herba Scutellariae Barbatae, the each 30-50g of Cortex Magnoliae Officinalis, Rhizoma Gastrodiae, Rhizoma Polygonati, the each 10-25g of Bulbus Allii.Alumen, Natrii Sulfas 3-5g.
Or, according to following component preparation, Aconitum carmichjaelii Debx., Fructus Toosendan, the each 50-70g of Fructus Litseae, Radix Phytolaccae, the Radix Pulsatillae, Cortex Cinnamomi, Fructus Xanthii, Herba Scutellariae Barbatae, the each 30-40g of Cortex Magnoliae Officinalis, Rhizoma Gastrodiae, Rhizoma Polygonati, the each 10-20g of Bulbus Allii, Alumen, Natrii Sulfas 3-4g.
Or, according to following component preparation, Aconitum carmichjaelii Debx., Fructus Toosendan, the each 60-80g of Fructus Litseae, Radix Phytolaccae, the Radix Pulsatillae, Cortex Cinnamomi, Fructus Xanthii, Herba Scutellariae Barbatae, the each 40-50g of Cortex Magnoliae Officinalis, Rhizoma Gastrodiae, Rhizoma Polygonati, the each 15-25g of Bulbus Allii, Alumen, Natrii Sulfas 4-5g.
Or, according to following component preparation, Aconitum carmichjaelii Debx., Fructus Toosendan, the each 55-75g of Fructus Litseae, Radix Phytolaccae, the Radix Pulsatillae, Cortex Cinnamomi, Fructus Xanthii, Herba Scutellariae Barbatae, the each 35-45g of Cortex Magnoliae Officinalis, Rhizoma Gastrodiae, Rhizoma Polygonati, the each 18-22g of Bulbus Allii, Alumen, Natrii Sulfas 3.5-4.5g.
The preparation method of captive animal sterilization delousing medication thing, by Aconitum carmichjaelii Debx., Fructus Toosendan, Fructus Litseae, Radix Phytolaccae, the Radix Pulsatillae, Cortex Cinnamomi, Fructus Xanthii, Herba Scutellariae Barbatae, Cortex Magnoliae Officinalis, Rhizoma Gastrodiae, Rhizoma Polygonati, Bulbus Allii, the lixiviate of use water extract method three times, after three times lixiviating solution merges, add Natrii Sulfas, steaming and decocting, to the thick Alumen that adds, is powder after being dried.
After being dried to powder, the 80-120 order that sieves, after sieve, gains, through the ultra-vioket radiation 15S that sterilizes, obtain captive animal sterilization delousing medication thing of the present invention.
Experimental data: with for mycotic experiment
Get 3 parts of each 50g of powder, be respectively charged into 500ml small beaker, add the organic solvent methanol of 5 times of weight of powder.Chloroform, petroleum ether.Under room temperature, soak 3 days, filtering and concentrating is to paste, and take a certain amount of extract and add Tween 80 and make emulsifying agent, 4 degrees Celsius of preservations,
Adopt growth rate method, get the vigorous strain of 6mm colony edge with card punch, be placed on the PDA flat board of dosing and cultivate, the sterilized water that adds equivalent with culture medium contrasts, each repetition 3 times, is placed in 25 degrees Celsius of cultivations, surveys each colony diameter by decussation method, represent the diameter of bacterium colony with meansigma methods, obtain rate of growth=(contrast colony diameter-processing colony diameter)/(contrast colony diameter-0.6) × 100% of Antifungi/antibacterial.(fungal culture)
The extract of 3 kinds of organic solvents is made to the PEA culture medium that final concentration is the extracting solution of 1mg/ml, get the spore suspension 10ul preparing in advance, being inoculated into diameter is the culture dish central authorities of 9cm, logical spreader is smeared evenly, in 25 degrees Celsius of incubators, cultivate 48 hours, observe spore germination quantity, 5 repetitions are established in every processing, average, calculate germination rate and the suppression ratio of spore.
Spore germination rate %=has sprouted spore count/microscopy spore sum × 100%
Suppression ratio %=(contrast germination rate-processing germination rate)/contrast germination rate × 100%
For the experiment of fungus, colony diameter (mm) and suppression ratio (100%), as following table
Bacterial content in feces, uses after the spray liquid feces of the present invention's 25% percentage ratio mass concentration, compared with not spraying feces of the present invention, and bacterium colony decreased number 50-56%. in it
Delousing experiment:
Be 15%, 25%, 35%, 45% mass percent concentration by the powder proportioning that adds water, get cattle louse with it, pig each 100 of louse with it, sprays respectively, then gets the Radix Stemonae 10% aqueous solution and spray, and contrasts as follows:
| Group | 15% | 25% | 35% | 45% | The Radix Stemonae 10% aqueous solution |
| 100 of cattle | Dead 92 | Dead 96 | Dead 93 | Dead 84 | Dead 82 |
| 100 of pig | Dead 94 | Dead 94 | Dead 90 | Dead 80 | Dead 84 |
Can find that by aforementioned proportion 25% mass percent concentration cootie killing effect is good.
Alkaloid content determination
Get 100g powder (Aconitum carmichjaelii Debx., Fructus Toosendan, the each 50g of Fructus Litseae, Radix Phytolaccae, the Radix Pulsatillae, Cortex Cinnamomi, Fructus Xanthii, Herba Scutellariae Barbatae, the each 30g of Cortex Magnoliae Officinalis, Rhizoma Gastrodiae, Rhizoma Polygonati, the each 10g of Bulbus Allii.Alumen, Natrii Sulfas 3g) as one group.
Get 100g powder (Aconitum carmichjaelii Debx., Fructus Toosendan, the each 70g of Fructus Litseae, Radix Phytolaccae, the Radix Pulsatillae, Cortex Cinnamomi, Fructus Xanthii, Herba Scutellariae Barbatae, the each 40g of Cortex Magnoliae Officinalis, Rhizoma Gastrodiae, Rhizoma Polygonati, the each 15g of Bulbus Allii.Alumen, Natrii Sulfas 4g).As two groups.
Get 100g powder (Aconitum carmichjaelii Debx., Fructus Toosendan, the each 60g of Fructus Litseae, Radix Phytolaccae, the Radix Pulsatillae, Cortex Cinnamomi, Fructus Xanthii, Herba Scutellariae Barbatae, the each 45g of Cortex Magnoliae Officinalis, Rhizoma Gastrodiae, Rhizoma Polygonati, the each 18g of Bulbus Allii.Alumen, Natrii Sulfas 5g).As three groups.
Every group, add 120ml extracting solution (oxolane: water: acetonitrile: acetic acid is by 50:25:20:1 preparation V/V%), smash to pieces and be slurry, filter paper filtering, centrifugal 5 minutes of filtrate, get supernatant 100ml, add 2ml glacial acetic acid, ultrasonic wave concussion 5 minutes, ammonia regulates PH10.5, boiling water is concentrated into dry, twice of a small amount of ammonia scrubbing residue of cooling rear use, centrifugal rear abandoning supernatant, residue water bath method, with 3ml, the phosphoric acid of mass ratio 7% dissolves, centrifugal 5 minutes again, clear liquid is for measuring TGA, select 600nm as measuring wavelength, under room temperature, react 30 minutes with polyformaldehyde phosphoric acid developer, after ultrasonic Treatment, calculate alkaloid, one group 2.01 milligram/gram.Two group 2.10 milligram/gram, three group 2.03 milligram/gram.Show that alkaloid of the present invention is greater than 2.0%.
Biological general glycoside is measured
Glycoside reacts with vanillin-sulfuric acid and produces aubergine, and at 550nm wavelength, there is absorption maximum at place, and within the scope of finite concentration, its concentration is directly proportional to absorbance, taking Saponin as reference substance, and quantitative assay.
Instrument and reagent
1, instrument
(1) visible ultraviolet spectrophotometer or 721 spectrophotometers (2) reflux
(3) single hole water-bath, (4) 10,5ml volumetric flask
(5) 90mm porcelain evaporating dish, (6) 500ml separatory funnel
(7) 10ml tool plug test tube, (8) 250ml flask
(9) measuring pipette
2, reagent
(1) ether, (2) 5% vanillin glacial acetic acid solutions
(3) concentrated sulphuric acid, (4) methanol
(5) n-butyl alcohol, (6) 2mg/ml Saponin standard solution: accurately take saponin monomer standard substance as Saponin Re10mg, be placed in 5ml volumetric flask, add dissolve with methanol and be diluted to scale.
(7) 70% ethanol, (8) glacial acetic acid
Operational approach
Specification Curve of Increasing: accurate Saponin Re standard solution 0,20,40,60,80, the 100ul of drawing, be placed in respectively tool plug test tube, in water-bath, wave most solvent, cooling, then add 5% vanillin glacial acetic acid solution 0.2ml and sulphuric acid sulphur 1.0ml, shake up, capping plug, in 60 DEG C of water-baths, heat 15min, cooling immediately, ice acetic acid 5.0ml, shake up, taking reagent as blank, measure absorbance, drawing standard curve at 550nm ± 1nm wavelength place.
Sample treatment: precision takes the each 10g(Aconitum carmichjaelii Debx. of three groups of powder of the present invention, Fructus Toosendan, the each 50g of Fructus Litseae, Radix Phytolaccae, the Radix Pulsatillae, Cortex Cinnamomi, Fructus Xanthii, Herba Scutellariae Barbatae, the each 30g of Cortex Magnoliae Officinalis, Rhizoma Gastrodiae, Rhizoma Polygonati, the each 10g of Bulbus Allii.Alumen, Natrii Sulfas 3g) as one group.Aconitum carmichjaelii Debx., Fructus Toosendan, the each 70g of Fructus Litseae, Radix Phytolaccae, the Radix Pulsatillae, Cortex Cinnamomi, Fructus Xanthii, Herba Scutellariae Barbatae, the each 40g of Cortex Magnoliae Officinalis, Rhizoma Gastrodiae, Rhizoma Polygonati, the each 15g of Bulbus Allii.Alumen, Natrii Sulfas 4g).As two groups.Aconitum carmichjaelii Debx., Fructus Toosendan, the each 60g of Fructus Litseae, Radix Phytolaccae, the Radix Pulsatillae, Cortex Cinnamomi, Fructus Xanthii, Herba Scutellariae Barbatae, the each 45g of Cortex Magnoliae Officinalis, Rhizoma Gastrodiae, Rhizoma Polygonati, the each 18g of Bulbus Allii.Alumen, Natrii Sulfas 5g).As three groups.), be placed in respectively 250ml flask, the 40ml that adds diethyl ether, water-bath backflow 2h, fling to the defat sample of ether, then it is colourless to be back to flow liquid with 70% alcoholic solution 30ml, and ether extracted liquid is put in evaporating dish, is concentrated into dryly in water-bath, and the residue 10ml that adds water makes to dissolve.With the full n-butanol extraction closing of 50ml water, re-extract 4 times, merges butanol extraction liquid, with the full Heshui washing of 20ml n-butyl alcohol.Butanol solution is transferred in evaporating dish, is concentrated into dryly in water-bath, with dissolve with methanol residue and transfer them in 10ml volumetric flask, is diluted to scale, shakes up, and obtains test liquid.
Sample determination: draw 20ul test liquid and be placed in tool plug test tube, by the time-and-motion study absorbance under " Specification Curve of Increasing " item, find corresponding total salidroside content on standard curve.
Calculate:
General glycoside (mg/100g)=C*V1*100/m*V2
In formula: C---absorbance per sample, try to achieve the amount of Saponin, mg from standard curve;
V1---sample extraction volume, ml;
V2---sample analysis volume ml;
M---sample quality, g.
Draw one group 1.52 of biological general glycoside milligram/gram, two group 1.58 milligram/gram, three group 1.54 milligram/gram, show that the biological general glycoside of powder of the present invention is greater than 1.5%.
Toxicity:
Acute oral (LD50) > 500mg/kg,
Acute percutaneous (LD 50) > 2000mg/kg,
Belong to low toxicity
Rat eyes are had to the slightly zest to moderate.
Object lesson 1
King family stable breeding pig, conventional health rubs wall, with the passing of time after, cause body of wall activity, on porcine skin, find that red speckle appears in louse, porcine skin, speckle hypotrichosis around.Use Aconitum carmichjaelii Debx. of the present invention, Fructus Toosendan, the each 50g of Fructus Litseae, Radix Phytolaccae, the Radix Pulsatillae, Cortex Cinnamomi, Fructus Xanthii, Herba Scutellariae Barbatae, the each 30g of Cortex Magnoliae Officinalis, Rhizoma Gastrodiae, Rhizoma Polygonati, the each 10g of Bulbus Allii.Alumen, Natrii Sulfas 3g.
By Aconitum carmichjaelii Debx., Fructus Toosendan, Fructus Litseae, Radix Phytolaccae, the Radix Pulsatillae, Cortex Cinnamomi, Fructus Xanthii, Herba Scutellariae Barbatae, Cortex Magnoliae Officinalis, Rhizoma Gastrodiae, Rhizoma Polygonati, Bulbus Allii, the lixiviate of use water extract method three times, after three times lixiviating solution merges, add Natrii Sulfas, steaming and decocting, to the thick Alumen that adds, is powder after being dried.The 80-120 order that sieves, after sieve, gains, through the ultra-vioket radiation 15S that sterilizes, obtain captive animal sterilization delousing medication thing of the present invention.Powder is added water and prepares the aqueous solution that becomes 25% mass ratio, and be that pig water pipe rinses twice every day, within continuous five days, stops using afterwards, then use double-edged fine-toothed comb carding, do not find louse and worm's ovum, meanwhile, and with this liquid wash colony house ground.The colony counts decline 50-56% of fungus, antibacterial.
Object lesson 2
Wait a family stable breeding pig, the redness that skin is wanted by louse, rub wall after inflammation suppurate, erythema occurs in flakes, and Pilus Sus domestica hai roll, uses Aconitum carmichjaelii Debx. of the present invention, Fructus Toosendan, the each 70g of Fructus Litseae, Radix Phytolaccae, the Radix Pulsatillae, Cortex Cinnamomi, Fructus Xanthii, Herba Scutellariae Barbatae, the each 40g of Cortex Magnoliae Officinalis, Rhizoma Gastrodiae, Rhizoma Polygonati, the each 15g of Bulbus Allii.Alumen, Natrii Sulfas 4g.
By Aconitum carmichjaelii Debx., Fructus Toosendan, Fructus Litseae, Radix Phytolaccae, the Radix Pulsatillae, Cortex Cinnamomi, Fructus Xanthii, Herba Scutellariae Barbatae, Cortex Magnoliae Officinalis, Rhizoma Gastrodiae, Rhizoma Polygonati, Bulbus Allii, the lixiviate of use water extract method three times, after three times lixiviating solution merges, add Natrii Sulfas, steaming and decocting, to the thick Alumen that adds, is powder after being dried.The 80-120 order that sieves, after sieve, gains, through the ultra-vioket radiation 15S that sterilizes, obtain captive animal sterilization delousing medication thing of the present invention.It is 12% methanol solution that powder is added to mass percent, and the mass ratio of powder and methanol solution is 1:15-18, and be that pig is cleaned 2 times every day, within continuous five days, stop using afterwards, and pig louse disappearance with it.
Object lesson 3
Liu family stable breeding cattle, pediculosis in hair, whipping is continuous, and agitation is pedaled ground with hoof, lie prone sleeping after market get rid of head shake ear and a cattle cheek, the formation speckle being snapped in hair, red swelling of the skin inflammation, occasionally occurs by pustule, for fungal infection, use the present invention (Aconitum carmichjaelii Debx., Fructus Toosendan, the each 60g of Fructus Litseae, Radix Phytolaccae, the Radix Pulsatillae, Cortex Cinnamomi, Fructus Xanthii, Herba Scutellariae Barbatae, the each 45g of Cortex Magnoliae Officinalis, Rhizoma Gastrodiae, Rhizoma Polygonati, the each 18g of Bulbus Allii.The powder that Alumen, Natrii Sulfas 5g make) adding water is configured as the aqueous solution of mass percent 25%, with watering can sprinkling,
Every day, sooner or later once, after one week, erythema disappeared, and the lower skin of hair recovers the normal colour of skin visited after three months, not recurrence.
Select 100 pigs of stable breeding to use the present invention as experimental group, select the pig of stable breeding that water is rinsed as a control group,, be compared as follows when delivering for sale from piglet 50 days:
| Group | Deliver natural law for sale | Body weight while delivering for sale | Ill number of elements during this time | Whether there are the parasites such as louse |
| Experimental group | 139 | 118kg | 4 | Have |
| Matched group | 152 | 106kg | 12 | Nothing |
Proportioning of the present invention is simple, easy to use, good antimicrobial effect, have obvious cootie killing effect, the present invention is taking Aconitum carmichjaelii Debx., Fructus Toosendan, Fructus Litseae as monarch drug, and Radix Phytolaccae, the Radix Pulsatillae, Cortex Cinnamomi, Fructus Xanthii, Herba Scutellariae Barbatae, Cortex Magnoliae Officinalis are ministerial drug, Rhizoma Gastrodiae, Rhizoma Polygonati, Bulbus Allii, Alumen are adjuvant drug, and Natrii Sulfas is for making medicine.Total alkaloid content of the present invention is higher than 2.0%, and biological general glycoside is greater than 1.5%, and the pet cat of louse, fungal infection, Canis familiaris L. amount to 86 routine effect comparisons, effective percentage 91.5%.
Claims (5)
1. a captive animal sterilization delousing medication thing, is characterized in that, according to following component preparation, Aconitum carmichjaelii Debx., Fructus Toosendan, the each 50-80g of Fructus Litseae, Radix Phytolaccae, the Radix Pulsatillae, Cortex Cinnamomi, Fructus Xanthii, Herba Scutellariae Barbatae, the each 30-50g of Cortex Magnoliae Officinalis, Rhizoma Gastrodiae, Rhizoma Polygonati, the each 10-25g of Bulbus Allii, Alumen, Natrii Sulfas 3-5g.
2. captive animal sterilization delousing medication thing according to claim 1, it is characterized in that, according to following component preparation, Aconitum carmichjaelii Debx., Fructus Toosendan, the each 50-70g of Fructus Litseae, Radix Phytolaccae, the Radix Pulsatillae, Cortex Cinnamomi, Fructus Xanthii, Herba Scutellariae Barbatae, the each 30-40g of Cortex Magnoliae Officinalis, Rhizoma Gastrodiae, Rhizoma Polygonati, the each 10-20g of Bulbus Allii, Alumen, Natrii Sulfas 3-4g.
3. captive animal sterilization delousing medication thing according to claim 1, it is characterized in that, according to following component preparation, Aconitum carmichjaelii Debx., Fructus Toosendan, the each 60-80g of Fructus Litseae, Radix Phytolaccae, the Radix Pulsatillae, Cortex Cinnamomi, Fructus Xanthii, Herba Scutellariae Barbatae, the each 40-50g of Cortex Magnoliae Officinalis, Rhizoma Gastrodiae, Rhizoma Polygonati, the each 15-25g of Bulbus Allii, Alumen, Natrii Sulfas 4-5g.
4. captive animal sterilization delousing medication thing according to claim 1, it is characterized in that, according to following component preparation, Aconitum carmichjaelii Debx., Fructus Toosendan, the each 55-75g of Fructus Litseae, Radix Phytolaccae, the Radix Pulsatillae, Cortex Cinnamomi, Fructus Xanthii, Herba Scutellariae Barbatae, the each 35-45g of Cortex Magnoliae Officinalis, Rhizoma Gastrodiae, Rhizoma Polygonati, the each 18-22g of Bulbus Allii, Alumen, Natrii Sulfas 3.5-4.5g.
One kind as arbitrary in claim 1-4 as described in the preparation method of captive animal sterilization delousing medication thing, it is characterized in that, by Aconitum carmichjaelii Debx., Fructus Toosendan, Fructus Litseae, Radix Phytolaccae, the Radix Pulsatillae, Cortex Cinnamomi, Fructus Xanthii, Herba Scutellariae Barbatae, Cortex Magnoliae Officinalis, Rhizoma Gastrodiae, Rhizoma Polygonati, Bulbus Allii, the lixiviate of use water extract method three times, after three times lixiviating solution merges, add Natrii Sulfas, steaming and decocting, to the thick Alumen that adds, is powder after being dried.
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| CN201410368788.1A CN104189518A (en) | 2014-07-30 | 2014-07-30 | Medicine for sterilizing and delousing captive animals |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN107375112A (en) * | 2017-08-31 | 2017-11-24 | 秦得翔 | A kind of washing lotion for preventing and treating cat lice and its application |
| CN107691506A (en) * | 2016-08-08 | 2018-02-16 | 庞锦霞 | A kind of aconite root vegetable insecticide and preparation method thereof |
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|---|---|---|---|---|
| US20070148262A1 (en) * | 2005-12-27 | 2007-06-28 | Ra Jeong C | Bactericidal and virucidal composition containing natural products |
| CN103446352A (en) * | 2013-08-07 | 2013-12-18 | 湖南农业大学 | Pharmaceutical composition for controlling bacterial infectious diseades of livestock and poultry and application of pharmaceutical composition |
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2014
- 2014-07-30 CN CN201410368788.1A patent/CN104189518A/en not_active Withdrawn
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070148262A1 (en) * | 2005-12-27 | 2007-06-28 | Ra Jeong C | Bactericidal and virucidal composition containing natural products |
| CN103446352A (en) * | 2013-08-07 | 2013-12-18 | 湖南农业大学 | Pharmaceutical composition for controlling bacterial infectious diseades of livestock and poultry and application of pharmaceutical composition |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107691506A (en) * | 2016-08-08 | 2018-02-16 | 庞锦霞 | A kind of aconite root vegetable insecticide and preparation method thereof |
| CN107375112A (en) * | 2017-08-31 | 2017-11-24 | 秦得翔 | A kind of washing lotion for preventing and treating cat lice and its application |
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