CN104146246A - Application of instant asparagus powder in food, medicine and healthcare product - Google Patents
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- CN104146246A CN104146246A CN201410341062.9A CN201410341062A CN104146246A CN 104146246 A CN104146246 A CN 104146246A CN 201410341062 A CN201410341062 A CN 201410341062A CN 104146246 A CN104146246 A CN 104146246A
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- 235000005340 Asparagus officinalis Nutrition 0.000 title claims abstract description 48
- 239000000843 powder Substances 0.000 title claims abstract description 38
- 239000003814 drug Substances 0.000 title claims abstract description 17
- 235000013305 food Nutrition 0.000 title claims abstract description 11
- 244000003416 Asparagus officinalis Species 0.000 title 1
- 241000234427 Asparagus Species 0.000 claims abstract description 47
- 230000002350 accommodative effect Effects 0.000 claims description 18
- 238000002360 preparation method Methods 0.000 claims description 10
- 235000013402 health food Nutrition 0.000 claims description 9
- 229940079593 drug Drugs 0.000 abstract description 6
- 239000001397 quillaja saponaria molina bark Substances 0.000 abstract description 6
- 229930182490 saponin Natural products 0.000 abstract description 6
- 150000007949 saponins Chemical class 0.000 abstract description 6
- 238000004904 shortening Methods 0.000 abstract description 4
- 230000004622 sleep time Effects 0.000 abstract description 3
- 230000006870 function Effects 0.000 abstract description 2
- 230000001105 regulatory effect Effects 0.000 abstract 2
- 230000007958 sleep Effects 0.000 description 24
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 description 10
- 238000012360 testing method Methods 0.000 description 9
- JYGXADMDTFJGBT-VWUMJDOOSA-N hydrocortisone Chemical compound O=C1CC[C@]2(C)[C@H]3[C@@H](O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 JYGXADMDTFJGBT-VWUMJDOOSA-N 0.000 description 8
- 206010022437 insomnia Diseases 0.000 description 8
- 208000024891 symptom Diseases 0.000 description 8
- 208000002173 dizziness Diseases 0.000 description 7
- 206010016256 fatigue Diseases 0.000 description 7
- 230000002618 waking effect Effects 0.000 description 7
- 239000002994 raw material Substances 0.000 description 6
- 230000008447 perception Effects 0.000 description 5
- 238000000574 gas--solid chromatography Methods 0.000 description 4
- 229960000890 hydrocortisone Drugs 0.000 description 4
- 238000012544 monitoring process Methods 0.000 description 4
- 206010019233 Headaches Diseases 0.000 description 3
- 230000007423 decrease Effects 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 3
- 231100000869 headache Toxicity 0.000 description 3
- 206010021403 Illusion Diseases 0.000 description 2
- 229920002774 Maltodextrin Polymers 0.000 description 2
- 239000005913 Maltodextrin Substances 0.000 description 2
- 239000002131 composite material Substances 0.000 description 2
- 229940035034 maltodextrin Drugs 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 230000003860 sleep quality Effects 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 206010041349 Somnolence Diseases 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 229910052785 arsenic Inorganic materials 0.000 description 1
- RQNWIZPPADIBDY-UHFFFAOYSA-N arsenic atom Chemical compound [As] RQNWIZPPADIBDY-UHFFFAOYSA-N 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 238000004042 decolorization Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000005059 dormancy Effects 0.000 description 1
- 230000035622 drinking Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 238000004108 freeze drying Methods 0.000 description 1
- 229910001385 heavy metal Inorganic materials 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 230000001537 neural effect Effects 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 230000001575 pathological effect Effects 0.000 description 1
- 239000000575 pesticide Substances 0.000 description 1
- 238000012827 research and development Methods 0.000 description 1
- 210000003296 saliva Anatomy 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 230000035807 sensation Effects 0.000 description 1
- 208000019116 sleep disease Diseases 0.000 description 1
- 230000004620 sleep latency Effects 0.000 description 1
- 208000020685 sleep-wake disease Diseases 0.000 description 1
- 238000002791 soaking Methods 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 239000010902 straw Substances 0.000 description 1
- 238000002137 ultrasound extraction Methods 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L19/00—Products from fruits or vegetables; Preparation or treatment thereof
- A23L19/01—Instant products; Powders; Flakes; Granules
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/385—Concentrates of non-alcoholic beverages
- A23L2/39—Dry compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Nutrition Science (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Medical Informatics (AREA)
- Pharmacology & Pharmacy (AREA)
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- General Health & Medical Sciences (AREA)
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Abstract
The invention discloses an application of instant asparagus powder in foods, medicines and healthcare products. When being used, the asparagus powder has the novel functions of regulating over-awakening, shortening the time to fall asleep, reducing the awakening time at night, shortening the time to fall asleep again and prolonging the sleep time. A great amount of asparagus saponin in the asparagus powder is a main functional component for regulating over-awakening.
Description
Technical field
The present invention relates to the purposes of instant asparagus powder, is the new purposes of instant asparagus powder in food, medicine and health food for the preparation of accommodative excess awakening specifically.
Background technology
(original name: Qinhuangdao Chang Sheng development in agricultural science and technology Co., Ltd) the published patent No. is 201110278589.8, name is called the product patent of " instant asparagus powder " in Qinhuangdao, instant asparagus powder Shi You Hebei province Chang Sheng nutrient health Science and Technology Ltd..Its process is: by fresh asparagus (dried asparagus or old stalk of asparagus, asparagus straws), be raw material, put into after crushed ultrasonic extraction tank, the water soaking 10-60 minute that adds 0.5-20 times of volume, boils 15-120 minute by routine or high pressure or supercritical ultrasonics technology, obtains extract; Extract is put into vacuum concentration pot Vacuum Concentration to solid content and reach 10-50%, through cooling 10-200 minute below 15 ℃, the centrifugal concentrated extracting solution that obtains; Concentrated extracting solution is added to the maltodextrin of 0-200% by its dry matter content, the dry or freeze-drying of spray-dried tower 140-190 ℃ of spraying, to moisture≤5%, makes instant asparagus powder.
In publication technical foundation, completed physical decolorization technical research, make its finished product become white powder, micro-sweet mouthfeel, the heavy metals such as plumbous arsenic reduce more than 10 times than national standard, and 190 kinds of residues of pesticides do not reach report limit, asparagus saponin(e >=12.5%.
Sleep?perception?and?the?multiple?sleep?latency?test?in?patientswith?primary?insomnia
L?I?L?I?HUANG1?,?2?,?JUNYING?ZHOU1,?ZHE?LI1,?FEI?LEI1?and?XIANGDONG?TANG1
1Sleep?Medicine?Center,?Translational?Neuroscience?Center,?West?China?Hospital,?Sichuan?University,?Chengdu,?China?and?2PharmaceuticalCollege,?Heilongjiang?University?of?Chinese?Medicine,?Harbin,?China
Keywords
hyperarousal,?multiple?sleep?latency?test,polysomnography,?primary?insomnia,questionnaires,?sleep?perception
Correspondence
Xiangdong?Tang,?Sleep?Medicine?Center,?WestChina?Hospital?of?Sichuan?University,?28?DianXin?Nan?Jie,?Chengdu?City,?Sichuan?Province610041,?China.
Tel.:?011-86-28-8542-2733;
fax:?011-86-28-8542-2632;
e-mail:[email protected]
Accepted?in?revised?form?15?May?2012;?received23?November?2011
DOI:?10.1111/j.1365-2869.2012.01028.x
Summary: this research is for checking patients with primary insomnia (PIPs), or well sleep person (GSCs) nighttime sleep consciousness and Sleep latency (MSLT) relation repeatedly in the daytime.We are by collecting polysomnogram (PSG) monitored data at a night, and subjective sleep data are by self-assessment, and MLST data are by above 4 20min nap of 8h monitoring.Experimenter comprises 122 patients with primary insomnias and 48 well sleep persons.Sleep consciousness computing formula is the subjective length of one's sleep/objective length of one's sleep 100%.There were significant differences (P<0.01) length of one's sleep that PSG monitoring time is (387.8 ± 100min) for patients with primary insomnia, self-assessment is (226.3 ± 160min), and GSCs is without performance notable difference (440.6 ± 53 with respect to 435.4 ± 65min).PIPs group, GSCs group sleep perception are respectively 56.4 ± 38.8%, 99.3 ± 13.6% (P<0.001).In PIPs group MSLT sleep perception, present negative correlation (r:-0.20 is to-0.25) with self-assessment and PSG monitoring sleep time.Within low minute, comparing with PIP, there is larger sleep-disorder with the PSG monitoring sleep time in those very few high score sleep perception (%).GSCs group does not show significant correlation.These results and data in literature show bringing into play potential key effect during 24h waking state is in insomnia problem pathologic, physiologic.
Above-mentioned article is about sleep perceptual disturbance and sleep awakening time study proof, and chronic insomnia mainly, because excessively awakening and sleep perceptual disturbance cause, shortens the awakening time or improves sleep consciousness relieving insomnia problem effectively.If clinical conventional sleep drug main reaches in dormant object by suppressing the neural mode of action of improving sleep consciousness at present, after early awakening, can not again fall asleep appears in the people of a lot of long-term sleeping and eating dormancy medicines, has dizzy rise phenomenon or phenomenon slow in reacting after early awakening.Instant asparagus powder has while applying in food, medicine and health food aspect the new purposes of accommodative excess awakening and finds no pass bibliographical information.
Summary of the invention
The object of the present invention is to provide the new purposes of instant asparagus powder, i.e. the new purposes of instant asparagus powder in food, medicine and health food for the preparation of accommodative excess awakening.
In fact, the present invention relates to the new purposes of instant asparagus powder in the food for the preparation of accommodative excess awakening.
Relate to the new purposes of instant asparagus powder in the medicine for the preparation of accommodative excess awakening.
Relate to the new purposes of instant asparagus powder in the health food for the preparation of accommodative excess awakening.
When instant asparagus powder of the present invention is applied in food, medicine or health food for the preparation of accommodative excess awakening, there is accommodative excess awakening, shorten time for falling asleep, reduce awake number of times at night, shorten time for falling asleep again, the new function that extends the length of one's sleep.
In order to understand better the essence of purposes of the present invention, will the new purposes in for the preparation of food, medicine field with accommodative excess awakening be described based on volunteer's test-meal below.
1. instant asparagus powder accommodative excess is awakened and cortisol levels result of study
37 volunteers of screening of research and development centre of Perfect (China) Co., Ltd., participate in test, in the time of 3 weeks, have 35 and take one's test.Result of the test is as follows:
1) impact on dropping asleep latency
From SRSS scale, finding has 28 to have the long problem of dropping asleep latency in 37 testers, 2 weeks rear dropping asleep latencies of tester's edible instant asparagus powder obviously shorten (P<0.01), and along with consumable products time lengthening time for falling asleep declines more obvious, in consumable products in the time of 3 weeks average time for falling asleep drop to 8.65min, and present significant difference (P<0.01), in Table 1.
2) impact on awakening number of times
Before edible in 37 persons of taking one's test, there are 10 and have awakening (n >=3 time) often, the symptom that tester's edible instant asparagus powder was awakened often after 2 weeks is obviously alleviated (P<0.01), and along with consumable products time lengthening is on average awakened number of times in stable state, and present significant difference (P<0.01), in Table 2.
3) on the sleep impact of time of the aftersensation of waking up
long symptom of awakening time after having 26 to exist wake up night in 37 testers, after tester's edible instant asparagus powder is awake after waking up after 2 weeks, the awakening time obviously shortens (P<0.01), and along with the consumable products time lengthening awakening time shorten of sleeping is more obvious, the aftersensation of on average waking up in the time of 3 weeks in consumable products is kept alert while in bed time shorten to 9min, and present significant difference (P<0.01), in Table 3.
4) cortisol levels situation
Saliva Determination of cortisol obviously decline (P<0.01) after tester's edible instant asparagus powder 2 weeks, and along with consumable products time lengthening Determination of cortisol declines more obvious, in consumable products in the time of 3 weeks average content drop to 6.27nmol/L, and present significant difference (P<0.01), in Table 4.
5) impact on sleep quality Self-assessment Scale total points
2 weeks rear subjective sensation sleep qualities of tester's edible instant asparagus powder obviously improve, SRSS mark obviously decline (P<0.01), and along with consumable products time lengthening SRSS mark declines more obvious, in consumable products in the time of 3 weeks average mark drop to 19.32 minutes, and present significant difference (P<0.01), in Table 5.
6) awake rear sense tired out improves situation
In tester, get up to have sense tired out 31 mornings, and consumable products, in the time of 3 weeks, all obviously alleviates with the edible front symptom tired out than 19 people (61.29%), wherein has this symptom of 12 people (38.71%) to disappear completely
.
7) dizziness headache improves situation
Dizzy or dizzy, headache symptom that 21 testers exist, consumable products dizzy or dizzy, have a headache transference cure or alleviation of 16 (69.57%) in the time of 2 weeks; Consumable products is in the time of 3 weeks, and with edible 2 weeks ratios, this remission degree keeps better
.
2. instant asparagus powder accommodative excess awakening study on the efficiency result
For the validity that further checking instant asparagus powder accommodative excess is awakened, we in Navy General Hospital Physical Examination Center, Armed health control center, Xiamen University Hospital Physical Examination center, mountain, PLA 180 hospital's health control centers, beautiful year large healthy Wuhan MEC, six contractor selections of Jilin University's first affiliated hospital's MEC 30 volunteers (wherein 28 MEC doctor by name or nurses, 2 MEC doctors' by name family members) verified instant asparagus powder accommodative excess awakening validity.Result of the test is as follows:
1) impact on dropping asleep latency
In 30 testers, edible instant asparagus powder is in the time of 2 weeks, and average dropping asleep latency, by within 65 minutes, shortening to 30.53 minutes before eating, declines 29.47 minutes, have significant difference (
p<0.01), refer to table 6.
2) impact on awakening number of times
Before edible in 30 persons of taking one's test, have 26 people to exist wake up often night, awake number of times at consumable products 21 people (80.77%) tester's in the time of 2 weeks average night shortening to for 3.0 times 1.83 times before by consumable products, declines 1.17 times, be significant difference (
p<0.01); Refer to table 7.
3) impact of awake rear awakening time
Difficulty falling asleep situation again after having 29 people to exist in 30 testers to wake up, consumable products is 23 people (79.31%) time shorten of awakening after waking up night in the time of 2 weeks; After waking up, the awakening time shortens to 37.76 minutes by eating first 72.41 minutes, declines 34.65 minutes, present significant difference (
p<0.01); Refer to table 8.
4) awake rear sense tired out alleviates
In 30 testers 28 people edible before morning get up to have sense tired out, consumable products in the time of 2 weeks 22 (78.57%) symptoms tired out obviously alleviate, wherein have 4 these symptoms to disappear completely.
5) awake rear main ill symptoms improves
30 person's of taking one's test consumable products are in the time of 2 weeks, and the ill symptomses such as 27 people are dizzy, nose heave, slow in reacting after waking up, decrease of memory, sleepy, lassitude are obviously alleviated or alleviate.
The specific embodiment
Below will be by embodiment, the invention will be further described.
Embodiment 1(instant asparagus drink)
The instant asparagus powder of take adds the auxiliary materials such as maltodextrin and makes that to break water be drinkable food as primary raw material, wherein active ingredient asparagus saponin content reaches 3.5%, more than every day, the amount of drinking reached 0.5g in asparagus saponin content.
Embodiment 2(instant asparagus powder health food)
Take instant asparagus powder as primary raw material, by instant asparagus powder and the composite health food of making of other raw material, for accommodative excess, awaken.More than the asparagus saponin(e amount wherein containing reaches 0.5g.
Embodiment 3(instant asparagus powder medicine)
Take instant asparagus powder as primary raw material, by instant asparagus powder and the composite medicine of making of other raw material, for accommodative excess, awaken.More than the asparagus saponin(e amount wherein containing reaches 0.5g.
Claims (3)
1. the new purposes of instant asparagus powder in the food for the preparation of accommodative excess awakening.
2. the new purposes of instant asparagus powder in the medicine for the preparation of accommodative excess awakening.
3. the new purposes of instant asparagus powder in the health food for the preparation of accommodative excess awakening.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410341062.9A CN104146246A (en) | 2014-07-17 | 2014-07-17 | Application of instant asparagus powder in food, medicine and healthcare product |
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| CN201410341062.9A CN104146246A (en) | 2014-07-17 | 2014-07-17 | Application of instant asparagus powder in food, medicine and healthcare product |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107518125A (en) * | 2016-06-22 | 2017-12-29 | 孙健 | A kind of formula and preparation method for sleeping jujube tea |
| CN108030099A (en) * | 2017-12-29 | 2018-05-15 | 广州硕维食品技术有限公司 | It is a kind of effectively to relieve stress the prescription nutrition food and preparation method for improving sleep |
| CN110150523A (en) * | 2019-06-14 | 2019-08-23 | 扬州大学 | A kind of novel fermentation asparagus beverage preparation method |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107518125A (en) * | 2016-06-22 | 2017-12-29 | 孙健 | A kind of formula and preparation method for sleeping jujube tea |
| CN108030099A (en) * | 2017-12-29 | 2018-05-15 | 广州硕维食品技术有限公司 | It is a kind of effectively to relieve stress the prescription nutrition food and preparation method for improving sleep |
| CN110150523A (en) * | 2019-06-14 | 2019-08-23 | 扬州大学 | A kind of novel fermentation asparagus beverage preparation method |
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Application publication date: 20141119 |
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