CN104138541A - Chinese herbal preparation for curing cobra respiratory system disease and producing method thereof - Google Patents
Chinese herbal preparation for curing cobra respiratory system disease and producing method thereof Download PDFInfo
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Abstract
Chinese herbal preparation for curing cobra respiratory system disease comprises the following raw materials, by weight proportion, of 5-7 parts of common andrographis herb, 10-12 parts of folium mori, 3-5 parts of radix zanthoxyli, 3-5 parts of honeysuckle, 6-8 parts of radix isatidis, 8-10 parts of centella, 12-14 parts of bamboo leaf and 15-17 parts of rhizome phragmitis. A producing method of the Chinese herbal preparation comprises the steps of reversely flowing, decocting, purifying and concentrating traditional Chinese herb. The Chinese herbal preparation has the advantages of being small in side effect, free of drug resistance and obvious in curing effect.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation about Naja disease and production method thereof, relate in particular to a kind of Chinese medicine preparation and production method thereof of preventing and treating Naja respiratory system disease.
Background technology
Naja (Latin formal name used at school: Naja) is commonly called as habu, meal spoon blunderbuss, five poisonous creatures: scorpion, viper, centipede, house lizard, toad Serpentis, is the general name of Serpentis class under Elaps, the general name of some the Serpentis classes in Shi She section, be mainly distributed in Asia, Africa subtropical and tropical zones.And refrigerant latitudes is little, the most obvious feature of Naja is cervical region, and while being on the hazard, the upright neck abdominal part of snakehead is extended to round fan-shaped.During because of its cervical region skin pleat expansion, back can present the magpie of a pair of beauty, seems glasses shape decorative pattern, therefore named Naja.
Naja whole body is all precious, and economic worth is very high, and in recent years, Naja is that supply falls short of demand on market always.This Carnis Serpentis delicious flavour, is rich in nutrition, and internal organs, skeleton, blood, bile and attaching organism all can be used as medicine, and especially cobra venom has now been made analgesic, and its analgesic effect is good, and without addiction, can replace the addictive drugs such as morphine.In addition, cobra venom preparation, to treatment motor neuron disease, as progressive spinal muscular atrophy disease, primary lateral sclerosis etc., has good curative effect.Visible, Naja is indispensable ingredient in China's Chinese medicine treasure-house.
Along with socioeconomic development, people are increasing to elapid demand, but ecological environment constantly destroyed, and add artificial catching and killing in a large number, peddle, and wild elapid resource is fallen sharply, and some local Naja is endangered.How to adopt an effective measure and protect existing wild Naja, exploitation artificial cultivation Naja resource, maintaining ecological balance has become the task of top priority.
The Naja of artificial cultivation because high humidity, the temperature of environment is high, suddenly cold and hot and when stuffy, subject to courses of infection and suffer from respiratory system disease.Relatively common are acute pneumonia, Serpentis humidity in duration of hibernation nest heat in high or midsummer, in nest all easily there is this disease in too sultry or sudden drop in temperature.Can be caused by flu in early days.When raising sanitation and hygiene are poor, this sick sickness rate is high, and this disease transmission obtains soon, if treatment not in time can infect group entirely in 3-5 days sometimes, causes large quantities of death.Also have the respiratory system disease being caused by virus, this disease is a kind of very serious disease to Serpentis.In majority of cases, can from Electronic Speculum, observe or be separated to a kind of virus that is called Paramyxo virus.This sick mortality rate is 8% one 87%, and aged Serpentis susceptible, by saliva droplet transmission, infects within latter 3 days and show clinical symptoms. stadium is about 5-12 days.The symptom in early stage of sick Serpentis is: do not urinate, vomit, arrange the green feces with mucus; There is subsequently obvious clinical symptoms: the elasticity of muscle disappears (Serpentis body is extended configuration), head chatter, ataxia.Finally, there is Respiratory symptoms: suddenly respiratory standstill, then there is spasm tempestuously, health is sloughed off contracting together, discharges brown secretions in trachea.The secondary inspection of corpse is visible, and pulmonary edema has mucus or in cheese sexual secretion.Histopathological examination can be seen the interstitial pneumonia with epithelial hyperplasia, blood vessel office mouth sleeve encephalitis and pancreatitis.The resistance to Serological testing of crossing Serpentis can be found the antibody of existence.
This type of Naja respiratory system disease is one of principal disease affecting the development of Naja artificial cultivation industry, causes huge loss to Naja artificial cultivation industry.The main antibiotics that adopts prevents and treats at present, but easily produces drug resistance and drug residue, and Serpentis is also had to certain infringement, uses for a long time, and therapeutic effect can decline gradually.
Summary of the invention
Based on the problem that has at present above-mentioned existence, the invention provides a kind of Chinese medicine preparation and production method thereof of preventing and treating Naja respiratory system disease.The present invention have toxic and side effects little, do not produce drug resistance, there is the feature of obvious therapeutical effect.
The present invention realizes by the following technical solutions:
The Chinese medicine preparation of control Naja respiratory system disease, it comprises the raw material of following weight proportioning: 5 parts-7 parts of Herba Andrographis, 10 parts-12 parts, Folium Mori, 3 parts-5 parts of Radix Zanthoxylis, 3 parts-5 parts of Flos Loniceraes, 6 parts-8 parts of Radix Isatidis, 8 parts-10 parts of Herba Centellaes, 12 parts-14 parts, Folium Bambusae, Rhizoma Phragmitis 15-17 part.
Preferably, the weight portion proportioning of each raw material of Chinese medicine is: 6 parts of Herba Andrographis, 11 parts, Folium Mori, 4 parts of Radix Zanthoxylis, 4 parts of Flos Loniceraes, 7 parts of Radix Isatidis, 9 parts of Herba Centellaes, 13 parts, Folium Bambusae, 16 parts of Rhizoma Phragmitiss.
Preferably, the weight portion proportioning of each raw material of Chinese medicine is: 5 parts of Herba Andrographis, 10 parts, Folium Mori, 3 parts of Radix Zanthoxylis, 3 parts of Flos Loniceraes, 6 parts of Radix Isatidis, 8 parts of Herba Centellaes, 12 parts, Folium Bambusae, 15 parts of Rhizoma Phragmitiss.
Preferably, the weight portion proportioning of each raw material of Chinese medicine is: 7 parts of Herba Andrographis, 12 parts, Folium Mori, 5 parts of Radix Zanthoxylis, 5 parts of Flos Loniceraes, 8 parts of Radix Isatidis, 10 parts of Herba Centellaes, 14 parts, Folium Bambusae, 17 parts of Rhizoma Phragmitiss.
The Chinese medicine preparation of described control Naja respiratory system disease, the production method of its Chinese medicine preparation comprises following steps:
Step 1) takes by weight Herba Andrographis, Folium Mori, Radix Zanthoxyli, Flos Lonicerae, Radix Isatidis, Herba Centellae, Folium Bambusae, Rhizoma Phragmitis and pulverizes respectively, mixes;
Step 2) add the purified water of 8 times of weight, reflux and decoct 2 hours, a filters to get filtrate; In filtering residue, add the purified water of 4 times of weight, then the decoction 2 hours that refluxes, b filters to get filtrate; Filtrate a and b are mixed, carry out concentrating under reduced pressure, cumulative volume is reduced to original 1/4, be Chinese medicine water extracting liquid, for subsequent use;
Step 3) is diluted to recipe quantity 1g/mL by Chinese medicine water extracting liquid by purified water, gets product, and is placed in 4 DEG C of environment and saves backup.
The Chinese medicine preparation of described control Naja respiratory system disease, the using method of its Chinese medicine preparation is: the finished product of having produced is applied to elapid feedstuff or joins in elapid normal drinking water and evenly mix, 1.5~3 grams/bar of serpent intake, 0.8~1.6 gram/bar of little Serpentis intake, the preventive dose use that reduces by half.
In the raw material of Chinese medicine that the present invention chooses, each medicine active ingredient is analyzed:
Herba Andrographis is acanthaceous plant.Herba Andrographis (formal name used at school: Andrographis paniculata (Burm. f.) Nees), has another name called Chun Lianqiuliu, Herba Andrographitis, Lan Helian, Radix Gentianae, golden Rhizoma et radix valerianae, Tremella aurantialba Bandoni et Zang hook, India's grass, Herba vallisneriae Spiralis etc.Annual herb plant, stem is square column type, multi-branched, long 50~70cm, joint slightly expands; Matter is crisp, frangibility.Single leaf is to life, the short or nearly stockless of petiole; Leaf-shrinkage, frangible, complete person is lanceolar or ovum shape lanceolar after launching, long 3~12cm, wide 2~5cm, tip is point gradually, and base portion wedge shape is downward, full edge or wavy; Upper surface green, lower surface celadon, two sides is smooth.Feeble QI, taste is extremely bitter.When stem and leaf is luxuriant at the beginning of autumn, tap the part that Herba Andrographis is gone up dryly, dry.Medicinal plants, has heat-clearing and toxic substances removing, antiinflammatory, reducing swelling and alleviating pain effect.Herba Andrographis has eliminating inflammation and expelling toxin effect, once be applied to clinically multi-infection disease, comprise trauma infection contamination, furuncle, carbuncle, erysipelas, upper respiratory tract infection, acute and chronic tonsillitis, acute and chronic pharyngitis, acute/chronic bronchitis, acute bacillary dysentery, acute gastroenteritis, urinary tract infection, endometritis, pelvic inflammatory disease, otitis media, periodontitis etc., all have curative effect in various degree.
Folium Mori, Chinese medicine name, English name: Mulberry Leaf, medical material formal name used at school: Folium Mori is the dried leaves of moraceae plants Mulberry, has another name called a Mulberry, Jing Sang, Fructus Mori tree, yellow wood etc., and there is production national most areas more.The many shrinkages of Folium Mori, fragmentation.Complete person has handle, and blade is avette or width egg shape after flattening, long 8~15cm, wide 7~13cm; Tip is point gradually, and base portion cuts shape, circle or heart-shaped, and there are sawtooth or crenation in edge, the irregular division having.Upper surface yellow green or light yellowish brown, what have has a little verruca; Lower surface color is slightly shallow, and vein is outstanding, and scun is netted, on arteries and veins, is dredged hair, arteries and veins base tool tuft.Matter is crisp.Feeble QI, lightly seasoned, micro-bitterness.Have the effects such as blood pressure lowering, blood fat, antiinflammatory, major function is dispelling wind and heat pathogens, clearing away lung-heat and moistening for dryness, liver heat removing and eyesight improving.For anemopyretic cold, lung-heat type cough, dizziness headache, conjunctival congestion is dim-sighted.Ministry of Public Health in 1993 determines that Folium Mori are food and medicine.Fructus Mori when children fruit viridescent, purple, aubergine darkly after maturation, sweet and sour is good to eat.
Radix Zanthoxyli (formal name used at school: Zanthoxylum nitidum(Roxb.) DC.) another name: nail-plate thorn (Foochow), enter under mountain tiger, anaesthetic rattan, Radix Zanthoxyli, leaf to thread a needle, the red le of falling hook, great Ye cat pawl le (Guangdong, Guangxi), red heart Zanthoxylum nitidum (Roxb.) DC, it is bejuco, be sheet or cylindrical short section, long 2~20cm, thick 0.5~6(10) cm.Surface light brown yellow or faint yellow, has foresythia or yellowish-brown similar round hole skin.Section is more smooth, skin zone's light brown, and woody part is faint yellow, visible proper alignment ring grain and intensive aperture.Matter is hard.Feeble QI perfume (or spice), the peppery numb tongue of acrid in the mouth and hardship.All can excavate the whole year, cleans, and section or section, dry.Nature and flavor: bitter, pungent, flat; Slightly poisonous.Function cures mainly: promoting the circulation of QI to relieve pain, blood circulation promoting and blood stasis dispelling, dispelling wind and removing obstruction in the collateral.The traumatic injury, rheumatic arthralgia, stomachache, the toothache that cause for qi depression to blood stasis, venom; The burning hot wound of external treatment soup.
Flos Lonicerae, has another name called Radix Ophiopogonis (formal name used at school: Lonicera japonica).Another name Caulis Lonicerae, silvernine, two color flower rattans, two precious rattans, right-hand rotation rattan, sub-Radix seu Caulis fici Martinii, Aicis galericulata rattan, Flos Lonicerae." Flos Lonicerae " one come from Compendium of Material Medica, because Flos Lonicerae is just opened as white, after transfer yellow to, Flos Lonicerae hence obtains one's name.Medical material Flos Lonicerae is Caprifoliaceae woodbine Radix Ophiopogonis and congener dry flower or the first flower of opening of band.Flos Lonicerae, bloom March, and five go out, micro-perfume (or spice), redly, Hua Chukai color is white for the base of a fruit, the yellow skin through, two day, therefore named Flos Lonicerae.Because a base of a fruit Flos Lonicerae, two pistils are visited outside again, in pairs, on very close terms, and shape is as female in hero together, again like Aicis galericulata to waving, therefore there is the title of Aicis galericulata rattan.This kind is the most significantly characterised in that the lobate bract with large shape.It is some resembles Lonicera confusa in person, but the bract of that kind is narrow thin but not lobate, the close raw pubescence of calyx tube, and the pubescence that the close life of sprig is curling, obvious different from this kind.The morphological variation of this kind is very large, no matter, at aspects such as the length ratios of fleece, the shape of leaf and length, fleece and the lip of size and corolla and the cylinder portion of branch, leaf, all varies widely.But it seems that all these variations more contact with ecological environment facies, shows the dependency between geographical distribution.Flos Lonicerae is described as the good medicine of heat-clearing and toxic substances removing from ancient times.The sweet cold fragrance of its property, clearing away heat with drugs sweet in flavor and cold in nature and not injuring one's stomach, fragrance thoroughly reaches and can be eliminating evil.Flos Lonicerae can dispelling wind-heat, also kind removing summer-heat blood poison, and for various febrile diseases, as fever of the body, dermexanthesis, send out the diseases such as speckle, pyretic toxicity carbuncle sore, laryngopharynx swelling and pain, all effect is remarkable.
The conventional another name of Radix Isatidis (Isatis tinctoria): indigo-blue, Isatis indigotica Fort (Indigofera tinctoria L, Baphicanthus cusia (nees) Brem. Polygonum tinctorium Ait) root, Radix Clerodenri Cyrtophylli are a kind of Chinese crude drugs.Cylindrical, slightly distortion, long 10~20cm, diameter 0.5~1cm.The light lark in surface or light brown yellow, have vertical wrinkle and supporting root trace, and hole skin is grown crosswise.Root head slightly expands, the petiole residual base that visible dirty-green or burgundy colyliform are arranged and intensive verruca.Body is real, and matter is slightly soft, section skin zone yellow-white, woody part yellow.Feeble QI, the micro-sweet rear bitterness of taste.Excavate autumn, removes silt, dries.All produce all over China.Radix Isatidis is divided into northern Radix Isatidis and Rhizoma Et Radix Baphicacanthis Cusiae, the root that northern Radix Isatidis source is cruciferae isatis (Isatis tinctoria L.) and careless Folium Isatidis (I. indigotica Fort.); Rhizoma Et Radix Baphicacanthis Cusiae is rhizome and the root of acanthaceous vegetable acanthaceous indigo (Baphicacanthus cusia (Nees) Brem.).There is heat-clearing and toxic substances removing, effect of removing heat from blood sore-throat relieving.For maculae caused by violent heat pathogen, crimson tongue is purple dark, mumps, sore throat, scarlet fever, major part pestilence, erysipelas, carbuncle.
Herba Centellae is the dry herb of samphire Herba Centellae Centella asiatica (L.) Urb., is the perennial draft of crawling.Another name: 18 lack, collapse jorum, Herba Calthae Membranaceae, Gotu Kola, Carnis Arca inflata shell grass, Hydrocotyle vulgaris L., Herba sambuci chinensis.Be born in by dark and damp wasteland, village, roadside, limit, ditch.Often crispatura into bulk.Root is cylindrical, long 2~4cm, diameter 1~1.5mm, the light yellow or lark in surface.Stem elongate curved, yellowish-brown, has thin vertical wrinkle, normal the palpus shape root of giving birth to joint on.The many shrinkages of blade, fragmentation, complete person is subcircular or kidney shape after flattening, diameter 1~4cm, celadon, there is thick cognate at edge; Long 3~the 6cm of petiole, distortion.Umbel axil is raw, short and small.Diachenium oblateness, has vertical rib and the fine-structure mesh stricture of vagina of obvious protuberance, and carpopodium is very short.Feeble QI, lightly seasoned.Summer, Qiu Erji gather, and remove silt, dry.Function cures mainly: clearing away heat-damp and promoting diuresis, removing toxic substances and promoting subsidence of swelling.For jaundice due to damp-heat, heatstroke diarrhoea, sand Stranguria stranguria with blood, carbuncle sore tumefacting virus, injury from falling down.
Folium Bambusae (Phyllostachys nigra (Lodd.) Munro var. henonis (Mitf.) Stapf ex Rendle) is the leaf of grass phyllostachys nigra (lodd.ex lindl.) munro var.henonis (miff.) spapf et rendle (bamboo).Effect of Folium Bambusae: clearing heat and relieving fidgetness, the diuresis of promoting the production of body fluid.Control calentura excessive thirst, pediatric epilepsy scared, cough with dyspnea is told nosebleed, flushed complexion, oliguria also, erosion of the oral mucosa tongue boil.1. not " not Lu ": main expectorant heat in the heart, cough with dyspnea.2. " property of medicine opinion ": main haematemesis pyretic toxicity wind, only quench one's thirst.3. " Treatise on Dietetic Therapy ": main cough with dyspnea, quench one's thirst, phlegm retention, sore throat, heat clearing away and restlessness relieving.4. " Japan hanako materia medica ": expectorant, control fanatical unhappiness, apoplectic aphasia in silence, high fever, headache wind syndrome of head, and cherish the pregnant number of people and revolve and fall down to the ground, spasmolytic is throbbed with fear, pestilence fan is vexed, pediatric epilepsy scared sky hangs.5. Zhang Yuansu: cool heart channel, beneficial vigour, heat extraction, slow spleen.6. " detailed outline ": decoct extract, gargle in tooth hemorrhagely, eluting anus is not received.7. " book on Chinese herbal medicine is just ": the irritated sleeplessness of reducing the asthenic fever, only excessive thirst, born fluid, Li little Shui, separates sore throat, and children's wind-heat infantile convulsion.8. " Chongqing hall random notes ": the wind of interior breath liver and gall, the heat of outer clear temperature administration, therefore there is the merit of the relieving convulsion of calming the nerves.9. " book on Chinese herbal medicine is new again ": cool heart spleen invigorating, control haematemesis, nose bleeding, hearing-improing and eyesight improving.
Rhizoma Phragmitis is the fresh or dry rhizome of grass phragmites communis Phragmites communis Trin..Another name: reed root, reed head.Perennial tall and big draft, has the shape of crawling subterraneous stem, sturdy, horizontal walk, internode hollow, tool bud on every joint.Stem is high 2~5 meters, the lower common tool white lead of joint.Leaf 2 row formulas are arranged, tool sheath; Sheath is embraced stem, without hair or tool fine, soft fur; Leaf celadon or aeruginous, wider, wire lanceolar, long 30~60 centimetres, wide 2~5 centimetres, coarse, tip is point gradually; Long 1~2 millimeter of the tip of a leaf, becomes one to take turns a mao shape.The large shape of panicle, top is raw, upright, sometimes slightly bending, and long 15~25 centimetres, sometimes or longer; Long 9~12 millimeters of small ear, mulberry or brown purple, rare faint yellow; Grain husk lanceolar, inner glume is about 1 times than coetonium; The 1st flower is generally male, long 8~15 millimeters of its lemma, and long 3~4 millimeters of glumelle, coarse on ridge; Long 9~16 millimeters of the 2nd lemma, the long gradually point of tip, the pubescence that basal disc tool is long 6~12 millimeters; Hermaphrodite flower tool stamen 3, gynoecium 1, style 2, stigma pinniform.Caryopsis, oval to Long Circle, separate with flower glume.9~October of florescence.Grow in river, bank, pond shallow water.All there is distribution the greater part, the whole nation.All can excavate the whole year, removes bud, fibrous root and membranaceous leaf, using fresh herb or dry.Rhizoma Phragmitis is containing Coixol, and protein 5%, fat 1%, carbohydrate 51%, asparagine 0.1%.Phragmites communis cellulose 48~54%, lignin approximately 18.2%, xylan approximately 12.4%, ash 2.8%.Polysaccharide hydrolysis produces D-xylose, L-arabinose, D-Glucose, D-galactose and two kinds of alduronic acid.Another containing volume vitamin B1, B2 and C, and tricin.Function cures mainly: clearing away heat and promoting production of body fluid, relieving restlessness, preventing or arresting vomiting, diuresis.For calentura excessive thirst, the gastric heat sound of vomiting of vomitting, cough due to lung-heat, lung abscess vomiting pus, the puckery pain of pyretic stranguria.
Beneficial effect of the present invention is:
1, Chinese medicine preparation of the present invention has advantages of natural, safe, low (or nothing) poison, efficient, raising immunity of organisms compared to existing technology, can adjust the imbalance state of body, reaches effect for the treatment of both the principal and secondary aspects of a disease;
2, Chinese medicine preparation of the present invention, can be used in the treatment of elapid respiratory system disease, and it adopts Chinese herbal medicine formula, and noresidue medicine after curing, has ensured the safety of medicine;
3, cheaper, the instant effect of Chinese medicine preparation expense of the present invention, curative effect is short, and cure rate is high;
4, Chinese medicine preparation of the present invention forms Herba Andrographis, Folium Mori, Radix Zanthoxyli, Flos Lonicerae, Radix Isatidis, Herba Centellae, Folium Bambusae, Rhizoma Phragmitis through the decoction concentration contracting that refluxes, there is the effects such as heat-clearing and toxic substances removing, antiinflammatory, reducing swelling and alleviating pain, removing summer-heat blood poison, removing heat from blood sore-throat relieving, thereby reached the effect of control Naja respiratory system disease.
Detailed description of the invention
Embodiment 1
Step 1) takes Herba Andrographis 6 kg, Folium Mori 11 kg, Radix Zanthoxyli 4 kg, Flos Lonicerae 4 kg, Radix Isatidis 7 kg, Herba Centellae 9 kg by weight, Folium Bambusae 13 kg, Rhizoma Phragmitis 16 kg pulverize respectively, mixes;
Step 2) add the purified water of 8 times of weight, reflux and decoct 2 hours, a filters to get filtrate; In filtering residue, add the purified water of 4 times of weight, then the decoction 2 hours that refluxes, b filters to get filtrate; Filtrate a and b are mixed, carry out concentrating under reduced pressure, cumulative volume is reduced to original 1/4, be Chinese medicine water extracting liquid, for subsequent use;
Step 3) is diluted to recipe quantity 1g/mL by Chinese medicine water extracting liquid by purified water, gets product, and is placed in 4 DEG C of environment and saves backup.
Usage: be applied to elapid feedstuff or join in elapid normal drinking water evenly and mix, 1.5~3 grams/bar of serpent intake, 0.8~1.6 gram/bar of little Serpentis intake, the preventive dose use that reduces by half.
Embodiment 2
Step 1) takes Herba Andrographis 5 kg, Folium Mori 10 kg, Radix Zanthoxyli 3 kg, Flos Lonicerae 3 kg, Radix Isatidis 6 kg, Herba Centellae 8 kg by weight, Folium Bambusae 12 kg, Rhizoma Phragmitis 15 kg pulverize respectively, mixes;
Step 2) add the purified water of 8 times of weight, reflux and decoct 2 hours, a filters to get filtrate; In filtering residue, add the purified water of 4 times of weight, then the decoction 2 hours that refluxes, b filters to get filtrate; Filtrate a and b are mixed, carry out concentrating under reduced pressure, cumulative volume is reduced to original 1/4, be Chinese medicine water extracting liquid, for subsequent use;
Step 3) is diluted to recipe quantity 1g/mL by Chinese medicine water extracting liquid by purified water, gets product, and is placed in 4 DEG C of environment and saves backup.
Usage: be applied to elapid feedstuff or join in elapid normal drinking water evenly and mix, 1.5~3 grams/bar of serpent intake, 0.8~1.6 gram/bar of little Serpentis intake, the preventive dose use that reduces by half.
Embodiment 3
Step 1) takes Herba Andrographis 7 kg, Folium Mori 12 kg, Radix Zanthoxyli 5 kg, Flos Lonicerae 5 kg, Radix Isatidis 8 kg, Herba Centellae 10 kg by weight, Folium Bambusae 14 kg, Rhizoma Phragmitis 17 kg pulverize respectively, mixes;
Step 2) add the purified water of 8 times of weight, reflux and decoct 2 hours, a filters to get filtrate; In filtering residue, add the purified water of 4 times of weight, then the decoction 2 hours that refluxes, b filters to get filtrate; Filtrate a and b are mixed, carry out concentrating under reduced pressure, cumulative volume is reduced to original 1/4, be Chinese medicine water extracting liquid, for subsequent use;
Step 3) is diluted to recipe quantity 1g/mL by Chinese medicine water extracting liquid by purified water, gets product, and is placed in 4 DEG C of environment and saves backup.
Usage: be applied to elapid feedstuff or join in elapid normal drinking water evenly and mix, 1.5~3 grams/bar of serpent intake, 0.8~1.6 gram/bar of little Serpentis intake, the preventive dose use that reduces by half.
Case study on implementation:
Case one: large quantities of death appears in foster Serpentis field, Chongzuo, Guangxi 136 age in days Naja, full group more than totally 1200 Serpentis, there is nearly 600 Naja morbidity, 37 Naja of dead, most of Naja disease just shows as mouth breathing, and head is miter angle with ground, spits out white foams, great quantity of water drinking, pants with " sound of flapping " sound of oppressiveness.Inappetence, slow in action, be reluctant to return nest, to open in visible oral cavity, oral cavity and have sticky expectorant but not red and swollen, the frequency of not prolonged illness Serpentis mouth breathing increases, and, there is ataxia in the sick Serpentis health that often reverses.There is spasm latter stage, last respiratory failure death.The Chinese medicine preparation that the application embodiment of the present invention one is produced is treated, and within first 3 days, carries out full group's drinking-water, every day 3 times, each 0.5mL, 1.5~3 grams/bar of serpent intake, 0.8~1.6 gram/bar of little Serpentis intake taking medicinal liquid as drinking-water.Do not drink water the sick Serpentis feedstuff feeding of smearing Chinese medicine preparation for isolation, before and after treatment, She Chang and surrounding are carried out to strict sterilization processing.Medication increase morbidity Naja, the clinical symptoms of sick Serpentis and mental status improvement again of full group afterwards in 3 days.After medication 5 days, 541 Naja clinical symptom disappearance, get well substantially, and cure rate reaches more than 95%.Cure after one month and pay a return visit, do not recur again.
Case two: the state of an illness appears in the Naja of certain body raiser's of Binyang, Guangxi more than 550 213 ages in days, approximately 300 Naja are breathed rale sounds, dehisce not close, and 3 is dyspnea due to pulmonary infection after diagnosing.The Chinese medicine preparation that the application embodiment of the present invention two is produced is treated, and within first 3 days, carries out full group's drinking-water, every day 3 times, each 0.5mL, 1.5~3 grams/bar of serpent intake, 0.8~1.6 gram/bar of little Serpentis intake taking medicinal liquid as drinking-water.Do not drink water the sick Serpentis feedstuff feeding of smearing Chinese medicine preparation for isolation, before and after treatment, She Chang and surrounding are carried out to strict sterilization processing.After medication 3 days, think except 15 Naja of morbidity Serious Mortality, Quan Qunwei increases morbidity Naja again, and the clinical symptoms of sick Serpentis and the mental status take a turn for the better.After medication 5 days, 285 Naja clinical symptom disappearance, get well substantially, and cure rate reaches 95%.Cure after one month and pay a return visit, do not recur again.
Case three: the state of an illness appears in the Naja of more than 800 180 ages in days of Guigang, Guangxi She Chang, has in more than 80 Naja oral cavity and has a large amount of mucus or purulent secretion, and their early stage, rinses the mouth to Serpentis, is coated with iodine glycerol, ichthyol etc.But the state of an illness does not have controlled, develop into pneumonia, and be transmitted to gradually Naja group.Successively there is more than 450 Naja ill during this period, dead 38 Naja.The Chinese medicine preparation that the application embodiment of the present invention three is produced is treated, and within first 3 days, carries out full group's drinking-water, every day 3 times, each 0.5mL, 1.5~3 grams/bar of serpent intake, 0.8~1.6 gram/bar of little Serpentis intake taking medicinal liquid as drinking-water.Do not drink water the sick Serpentis feedstuff feeding of smearing Chinese medicine preparation for isolation, before and after treatment, She Chang and surrounding are carried out to strict sterilization processing.Medication increase morbidity Naja, the clinical symptoms of sick Serpentis and mental status improvement again of full group afterwards in 3 days.After medication 5 days, 400 Naja clinical symptom disappearance, get well substantially, and cure rate reaches more than 95%.Cure after one month and pay a return visit, do not recur again.
Claims (6)
1. prevent and treat the Chinese medicine preparation of Naja respiratory system disease for one kind, it is characterized in that, it comprises the raw material of following weight proportioning: 5 parts-7 parts of Herba Andrographis, 10 parts-12 parts, Folium Mori, 3 parts-5 parts of Radix Zanthoxylis, 3 parts-5 parts of Flos Loniceraes, 6 parts-8 parts of Radix Isatidis, 8 parts-10 parts of Herba Centellaes, 12 parts-14 parts, Folium Bambusae, Rhizoma Phragmitis 15-17 part.
2. the Chinese medicine preparation of control Naja respiratory system disease according to claim 1, it is characterized in that, the weight portion proportioning of each raw material of Chinese medicine is: 6 parts of Herba Andrographis, 11 parts, Folium Mori, 4 parts of Radix Zanthoxylis, 4 parts of Flos Loniceraes, 7 parts of Radix Isatidis, 9 parts of Herba Centellaes, 13 parts, Folium Bambusae, 16 parts of Rhizoma Phragmitiss.
3. the Chinese medicine preparation of control Naja respiratory system disease according to claim 1, it is characterized in that, the weight portion proportioning of each raw material of Chinese medicine is: 5 parts of Herba Andrographis, 10 parts, Folium Mori, 3 parts of Radix Zanthoxylis, 3 parts of Flos Loniceraes, 6 parts of Radix Isatidis, 8 parts of Herba Centellaes, 12 parts, Folium Bambusae, 15 parts of Rhizoma Phragmitiss.
4. the Chinese medicine preparation of control Naja respiratory system disease according to claim 1, it is characterized in that, the weight portion proportioning of each raw material of Chinese medicine is: 7 parts of Herba Andrographis, 12 parts, Folium Mori, 5 parts of Radix Zanthoxylis, 5 parts of Flos Loniceraes, 8 parts of Radix Isatidis, 10 parts of Herba Centellaes, 14 parts, Folium Bambusae, 17 parts of Rhizoma Phragmitiss.
5. the Chinese medicine preparation of control Naja respiratory system disease according to claim 1, is characterized in that, the production method of described Chinese medicine preparation comprises following steps:
Step 1) takes by weight Herba Andrographis, Folium Mori, Radix Zanthoxyli, Flos Lonicerae, Radix Isatidis, Herba Centellae, Folium Bambusae, Rhizoma Phragmitis and pulverizes respectively, mixes;
Step 2) add the purified water of 8 times of weight, reflux and decoct 2 hours, a filters to get filtrate; In filtering residue, add the purified water of 4 times of weight, then the decoction 2 hours that refluxes, b filters to get filtrate; Filtrate a and b are mixed, carry out concentrating under reduced pressure, cumulative volume is reduced to original 1/4, be Chinese medicine water extracting liquid, for subsequent use;
Step 3) is diluted to recipe quantity 1g/mL by Chinese medicine water extracting liquid by purified water, gets product, and is placed in 4 DEG C of environment and saves backup.
6. the Chinese medicine preparation of control Naja respiratory system disease according to claim 1, it is characterized in that, the using method of described Chinese medicine preparation is: the finished product of having produced is applied to elapid feedstuff or joins in elapid normal drinking water evenly and mix, the preventive dose use that reduces by half.
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CN104998111A (en) * | 2015-07-29 | 2015-10-28 | 邓克统 | Chinese traditional medicine preparation preventing and curing peacock respiratory system disease and production method thereof |
CN107647117A (en) * | 2017-11-17 | 2018-02-02 | 广西雷村蛇场蛇业有限公司 | A kind of small snake special feed of cobra and preparation method thereof |
CN107864925A (en) * | 2017-11-17 | 2018-04-03 | 广西雷村蛇场蛇业有限公司 | A kind of cultural method before the meat cobra listing of artificial farming |
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CN103120267A (en) * | 2013-02-28 | 2013-05-29 | 灵山县园丰牧业有限公司 | Feed for lingshan patridge chicken |
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CN1569181A (en) * | 2004-05-09 | 2005-01-26 | 王健伟 | Chinese medicine for preventing and treating air pollution harm and its preparation method |
CN1840113A (en) * | 2006-01-23 | 2006-10-04 | 冯东 | Chinese medicinal preparation for treating viral influenza |
CN102920946A (en) * | 2012-11-28 | 2013-02-13 | 蒋常德 | Preparation method of Chinese herbal medicinal active fermentation broth for preventing and treating porcine infectious diseases |
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CN104998111A (en) * | 2015-07-29 | 2015-10-28 | 邓克统 | Chinese traditional medicine preparation preventing and curing peacock respiratory system disease and production method thereof |
CN107647117A (en) * | 2017-11-17 | 2018-02-02 | 广西雷村蛇场蛇业有限公司 | A kind of small snake special feed of cobra and preparation method thereof |
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