CN104120034A - Method for extracting volatile oil under ultrahigh pressure - Google Patents
Method for extracting volatile oil under ultrahigh pressure Download PDFInfo
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Abstract
The invention discloses a method for extracting volatile oil under an ultrahigh pressure. The method comprises the following steps: 1, taking a volatile oil-containing plant raw material, and processing to form blocks or particles; 2, extracting the plant raw material obtained in step 1 by using a solvent under ultrahigh pressure conditions; and 3, separating the solvent and volatile oil to obtain volatile oil. Crude volatile oil in plants can be efficiently obtained by selecting and controlling the extraction solvent, the extraction time and the extraction pressure through the method, and the method for extracting the crude volatile oil has the advantages of short extraction time, less energy consumption, and avoiding of heat damages of active components by adopting a low temperature, and is especially suitable for temperature-sensitive volatile oil easy to oxidize-decompose and deteriorate.
Description
Technical field
The present invention relates to a kind of extracting method of volatile oil, particularly from the plant material that contains volatile oil, extract the method for volatile oil by superelevation platen press
Background technology
Volatile oil claims again essential oil, be present in plant materials that a class can obtain with wet distillation with the not miscible volatility oily composition of water, often there is special aromatic odour.In Chinese medicine, there are many medicinal materials to contain volatile oil component, conventionally there is very strong pharmacologically active.As Radix Bupleuri volatile oil has the effect of well bringing down a fever, refrigerant, antiinflammation that spearmint oil has, Oleum Bulbus Allii can be treated bronchitis, pneumonia and fungal infection, that Oils, Zingiber officinale has is antipyretic, analgesia, sedative effect, Rhizoma Chuanxiong oil has expansion of cerebral vascular effect, the volatile oil of frankincense, myrrh have good promoting blood circulation and removing blood stasis, improve microcirculatory effect etc.Traditional medicine volatile oil complicated component, is mainly micromolecular aldehydes, ester compound, monoterpene, sesquiterpenoids and small molecules aromatic compound etc., and majority is colourless or faint yellow, minority is brown color, redness, green etc.Volatile oil has special fragrance mostly, and physico-chemical property is active.Volatile oil has very strong volatility, and pure volatile oil at normal temperatures can very fast all volatilizations.Volatile oil is brought into play important therapeutic action in much Chinese medicine, is indispensable effective constituent, radix bupleuri, Rhizoma Zingiberis Recens volatile oil in radix bupleuri as familiar in us drink, the volatile oil of wrinkled giant hyssop in ageratum, dried orange peel, purple perilla, the root of Dahurain angelica.Traditional Chinese medicine theory thinks, volatile oil has fragrance and walks to go here and there function, can bring into play fast curative effect.Modern medicines research shows, volatile oil molecular weight is little, and fat-soluble strong, easily, through microbial film in body, bioavailability is high, can absorb fast onset, consistent with traditional Chinese medicine theory.
The extraction of traditional medicine volatile oil mainly contains two class methods: one, dry distillation: medicine is positioned over to dry slipping in device, by heating, volatile component is slipped out.Two, wet distillation: medicine and water are sneaked in distiller, by water vapour, volatile component is brought out.Conventional is steam distillation at present.But steam distillation is not suitable for the extraction of thermally labile component, easily there is chemical transformation in long-time and water azeotropic, to some heat-sensitive materials be easily oxidized, the reaction such as polymerization causes sex change; As water-soluble in extract vapour pressure can significantly decline, and the Chinese medicinal materials dissolving each other for some and water can not effectively extract; If the impurity in reaction mixture has volatility, just can not ensure the purity of extracted volatile oil, and the yield of volatile oil is also very low, required time is longer, be difficult to keep the original fresh fragrance of volatile oil, reduced the value as spices, also can exert an influence to the curative effect of some preparations.
The full name of ultra-high voltage is " superelevation isostatic cool pressing (Ultra high isostatic hydrostatic pressure at room temperature) ", referred to as isostatic cool pressing, refers to the hydrostatic pressure of pressure at 100～1000MPa.Super-high pressure biological processing technology Application Areas is very extensive, for scientific research, product development, the technological innovation of biology, medicine and food engineering provide new platform.The application of superhighpressure technology mainly contains: the temperature sterilization of temperature-sensitive food, is difficult for flowing and being easily charred food sterilizing, beans, milk-product processing, the processing of fish product, frozen product processing, tinned pre-processing, the processing of grain, starch denaturalization processing, protein denaturation processing, inactivation of virus, produces vaccine, processes blood plasma, biological extraction, bio-pharmaceuticals, Chinese medicine is produced, the sterilization of medicine equipment, the processing of wine, the extraction of natural essence etc.As the new field of a multidisciplinary intersection, superhighpressure technology, in worldwide industrialization, only has the time of more than ten years.The relevant subject study of China taking the food engineering scholar of universities and colleges as main flow launches in succession for over ten years, and obtains gratifying achievement.But aspect industrialization, substantially also in the blank stage.
There is bibliographical information based on this new technology in traditional Chinese medicine extraction field: compare with traditional extraction technology, ultra-high voltage extractive technique can shorten extraction time greatly, reduce energy consumption, reduce the stripping of impurity component, improve yield of effective constituent etc., therefore we intend, by the research of ultra-high voltage extractive technique, improving our extraction efficiency.
Ultra-high voltage extractive technique is in the research in the field of extraction, concentrate on Chinese medicine water extraction, alcohol extracting, extracting solution taking activeconstituents as index and medicinal extract, the present invention finds unexpectedly, use ultra-high voltage extractive technique to extract traditional medicine volatile oil and can obtain efficiently the naphtha in plant, the method for this extraction naphtha also has that extraction time is short, energy consumption is few, low temperature is avoided the advantages such as activeconstituents heat collapse simultaneously; Be directed to temperature especially more responsive, oxidizable decomposition and rotten volatile oil.
Summary of the invention:
The object of this invention is to provide a kind of method of high efficiency extraction naphtha, provide an efficiently technique means easily for obtaining volatile oil, realized energy-conservation and effect resources effective utilization.
Method of the present invention, comprises the following steps:
Step 1, gets the plant material that contains volatile oil, is processed into piece or particle;
Step 2, extracts with solvent plant material to step 1 under uht conditions;
Step 3, separates solvent and volatile oil, obtains volatile oil;
Wherein, plant material described in step 1, includes but not limited to the plant that Labiatae (peppermint, purple perilla, wrinkled giant hyssop etc.), pulse family (dalbergia wood), Illiciaceae (anise), Rhizoma Arisaematis thirsty (Rhizome of Grass leaf Sweelflag), umbelliferae (fennel, Radix Angelicae Sinensis, coriander, the root of Dahurain angelica, Ligusticum wallichii etc.), composite family (tarragon, oriental wormwood punt-pole, rhizoma atractylodis, the bighead atractylodes rhizome, the banksia rose etc.), Rutaceae (orange, tangerine, Chinese prickly ash etc.), Lauraceae (camphor tree, Chinese cassia tree etc.), Zingiber (ginger, turmeric, root tuber of aromatic turmeric etc.) etc. contain volatile oil.
Described piece or the particle of being processed into refers to and includes but not limited to it to carry out cutting, fragmentation or pulverization process, is processed into if desired powder to increase surface-area, improves extraction efficiency.
Wherein, solvent described in step 2 is selected from any solvent that can dissolve traditional medicine volatile oil, preferred: water, ethanol, methyl alcohol, ether, chloroform, ethyl acetate, sherwood oil, normal hexane, propyl carbinol and their mixture, in these solvents, the mixture of preferred alcohol of the present invention and second alcohol and water, as 40%～100% ethanolic soln, further preferably 80%～95% ethanol.The consumption of described solvent is 1-60 times of volume of Chinese medicinal materials weight, i.e. the Chinese medicinal materials that contains volatile oil of 1 part of weight need to add the solvent of 1～60 times of volume, is preferably 5～25 times.(wherein solvent load is that 1-60 times of volume of Chinese medicinal materials weight is the conventional phraseology in traditional Chinese medicine research field, as adds 10 times of 100g medicinal material to measure the solvent that volume of solvent need to add 1000ml, by that analogy.）
When described in the application, extracting mode extracts for the volatile oil of rhizoma atractylodis, its concrete technology is;
Get rhizoma atractylodis medicinal material, add 1-60 40%～100% ethanol doubly, under 100-1000Mpa uht conditions, extract 5-30min, filter and obtain extracting solution, extracting solution, 40-90 DEG C of underpressure distillation, obtains volatile oil.
Preferably, get rhizoma atractylodis medicinal material, add 5-25 80%～95% ethanol doubly, under 200-800Mpa uht conditions, extract 5-30min, filter and obtain extracting solution, extracting solution, 40-90 DEG C of underpressure distillation, obtains volatile oil.
More preferably: get rhizoma atractylodis medicinal material 20g, add 200ml95% ethanol, under 400Mpa uht conditions, extract 20min, filter and obtain extracting solution, extracting solution, 60 DEG C of underpressure distillation, obtains volatile oil, is Rhzoma Atractylodis Lanceae volatile oil crude product after testing.
The ultra-high voltage extraction equipment that the present invention uses belongs to prior art, can adopt the equipment that is applicable to traditional Chinese medicine extraction of any manufacturer production, report is selected from the equipment of any model, as: the ultrahigh pressure treatment equipment of the HPP.L2-600/5 of China's vast ultra-high voltage engineering of Tyson center, Tianjin manufacturer production.
The ultra-high voltage extraction equipment that the present invention adopts, in the time extracting, needing control pressure scope is 100～1000Mpa, is preferably 200～800Mpa, is further optimized for 400～600Mpa.
Each time length of extracting of ultra-high voltage can change in suitable scope, as 1-30 minute, is preferably 3～20 minutes, further most preferably 5～10 minutes.
Described extraction is by oil plant raw material and solvent, is placed in ultra-high voltage extraction equipment and carries out ultra-high voltage extraction, and the volatile oil in Chinese medicinal materials is fully dissolved in solvent, thereby obtains a kind of extracting solution that contains volatile oil.
Separation solvent and volatile oil described in step 3, can adopt distillation under vacuum or fractionating process, as steamed solvent in distiller, stay in distiller is volatile oil, still-process need regulate temperature at 30～90 DEG C, is preferably 40～80 DEG C, more preferably 50～65 DEG C.
The present invention extracts naphtha and has that extraction time is short, energy consumption is few, low temperature is beneficial to activeconstituents and exempts from the advantages such as heat collapse, and particularly volatile oil is more responsive to temperature, and oxidizable decomposition and rotten, so the low temperature feature of this technology has advantage especially.
Below data further illustrate beneficial effect of the present invention by experiment.
Adopt ultra-high voltage 95% extraction using alcohol and normal reflux to extract Rhzoma Atractylodis Lanceae volatile oil simultaneous test prior art as an example of rhizoma atractylodis example: 95% ethanol is conventional to be extracted:
Rhizoma atractylodis medicinal material is slightly broken, gets 3 parts, and every part of 20g measures 95% alcohol reflux 30min, 1h, 1.5h for 10 times respectively, filtering extracting solution, and 60 DEG C of decompression recycling ethanols, obtain alcohol extract (slightly oil)
The present invention: 95% ethanol ultra-high voltage extracts:
Rhizoma atractylodis medicinal material is slightly broken, gets 3 parts, every part of 20g, and 10 times of amount 95% ethanol 400Mpa ultra-high voltage extract 10min respectively, 20min and 30min, filtering extracting solution, 60 DEG C of decompression recycling ethanols, obtain alcohol extract (slightly oil)
Table 1. rhizoma atractylodis 95% ethanol ultra-high voltage and refluxing extraction comparative test result ultra-high voltage extract 400Mpa 10min400Mpa 20min400Mpa 30min extraction yield 12.15%12.10%12.3% refluxing extraction 30min1.5h2h extraction yield 6.02%10.98%10.32%
Can find out from upper table conclusion, alcohol extracting oil-containing medicinal material has very high efficiency, and 400MPa extracts 10 minutes, can meet or exceed the extraction effect of the conventional 1.5h～2h of extraction, and extraction efficiency is conventional 9 times of extracting.
Accompanying drawing is that the thin layer of the volatile oil prepared according to " Chinese Pharmacopoeia " annex ID " volatile oil extraction and determination method " of rhizoma atractylodis tradition alcohol extract, rhizoma atractylodis ultra-high voltage alcohol extract, rhizoma atractylodis extraction by steam distillation volatile oil and rhizoma atractylodis control medicinal material is differentiated, known ultra-high voltage extracts with conventional gained naphtha and the volatile oil extracting all has good consistence.
Visible ultra-high voltage extracts remarkable for the thick oily extraction effect of oil-containing medicinal material, can realize higher extraction efficiency and extraction effect, for high efficiency extraction volatile oil provides new solution route.
Volatile oil is often stored in glandular hairs, grease chamber, oil cell or the oil pipe of epidermis, and great majority become oil droplet state to exist.Sometimes volatile oil and resin coexist in resin canal (as loose stem), and minority exists (if the product wintergreen oil after checkerberry glucoside, its hydrolysis is as the principal constituent of wintergreen oil) taking the form of glucoside.Ultra-high voltage extracts the impact of naphtha extraction efficiency is mainly reflected in to the pressure difference that has formed superelevation inside and outside grease chamber, oil cell, extract solvent under hyperpressure promotes rapid permeability in inside plants vascular bundle and glandular cell.Along with pressure raises rapidly, grease chamber's structure or oil cell volume are compressed, exceed its deformation limit, can cause grease chamber and oil cell to break, and intracellular volatile oil contacts dissolved with solvent.Release generally can complete (general release time < 2s) within several seconds, histiocytic pressure is reduced to rapidly normal pressure from the ultra-high voltage of hundreds of MPa, under opposite direction pressure-acting, the explosion that fluid and drug matrices volume occur is expanded, to cell walls, cytolemma, plasma membrane, nuclear membrane, vacuole, the strong impact of the formation such as microtubule causes and deforms and occur loose, hole, the structural changes such as break, effective constituent fully contacts with solvent, the solution that has dissolved effective constituent can spread rapidly to extracellular, thereby realize high efficiency extraction
Brief description of the drawings
The alcohol extracting of Fig. 1 ultra-high voltage, traditional alcohol extracting and volatile oil sample thin layer are differentiated
Embodiment
Further illustrate by the following examples the present invention, but not as limitation of the present invention.
Embodiment 1
Get rhizoma atractylodis medicinal material 20g, add 200ml95% ethanol, under 400Mpa uht conditions, extract 10min, filter and obtain extracting solution, extracting solution, at 60 DEG C of decompression recycling ethanols, obtains naphtha, is Rhzoma Atractylodis Lanceae volatile oil crude product 2.43g after testing, yield 12.15%.
Embodiment 2
Get rhizoma atractylodis medicinal material 20g, add 1200ml40% ethanol, under 1000Mpa uht conditions, extract 5min, filter and obtain extracting solution, extracting solution, at 40 DEG C of decompression recycling ethanols, obtains naphtha 2.06g, yield 10.3%.
Embodiment 3
Get rhizoma atractylodis medicinal material 20g, add 60ml dehydrated alcohol, under 100Mpa uht conditions, extract 30min, filter and obtain extracting solution, extracting solution, at 90 DEG C of decompression recycling ethanols, obtains naphtha 2.23g, yield 11.15%.
Embodiment 4
Get rhizoma atractylodis medicinal material 200g, add 1000ml95% ethanol, under 200Mpa uht conditions, extract 5min, filter and obtain extracting solution, extracting solution, at 30 DEG C of decompression recycling ethanols, obtains naphtha 18.76g, yield 9.38%.
Embodiment 5
Get rhizoma atractylodis medicinal material 200g, add 5000ml80% ethanol, under 800Mpa uht conditions, extract 30min, filter and obtain extracting solution, extracting solution, at 40 DEG C of decompression recycling ethanols, obtains naphtha 20.83.g, yield 10.42%.
Embodiment 6
Get Radix Angelicae Sinensis medicinal material 20g, add 200ml95% ethanol, under 400Mpa uht conditions, extract 10min, filter and obtain extracting solution, extracting solution, at 60 DEG C of decompression recycling ethanols, obtains naphtha 0.83.g, yield 4.15%.
Embodiment 7
Get angelica root 20g, add 200ml95% ethanol, under 400Mpa uht conditions, extract 20min, filter and obtain extracting solution, extracting solution, at 80 DEG C of decompression recycling ethanols, obtains naphtha 0.65.g, yield 3.25%.
Embodiment 8
Get Ligusticum chuanxiong Hort 20g, add 200ml95% ethanol, under 400Mpa uht conditions, extract 20min, filter and obtain extracting solution, extracting solution, at 65 DEG C of decompression recycling ethanols, obtains naphtha 0.71.g, yield 3.55%.
Embodiment 9
Get tarragon medicinal material 20g, add 200ml95% ethanol, under 400Mpa uht conditions, extract 20min, filter and obtain extracting solution, extracting solution, at 60 DEG C of decompression recycling ethanols, obtains naphtha 0.54.g, yield 2.7%.
Embodiment 10
Get Rhizoma Atractylodis Macrocephalae 20g, add 200ml95% ethanol, under 400Mpa uht conditions, extract 20min, filter and obtain extracting solution, extracting solution, at 60 DEG C of decompression recycling ethanols, obtains naphtha 0.81.g, yield 4.05%.
Embodiment 11
Get Chinese prickly ash medicinal material 20g, add 200ml95% ethanol, under 400Mpa uht conditions, extract 20min, filter and obtain extracting solution, extracting solution, at 60 DEG C of decompression recycling ethanols, obtains naphtha 1.46.g, yield 7.3%.
Embodiment 12
Get Chinese cassia tree medicinal material 20g, add 200ml95% ethanol, under 400Mpa uht conditions, extract 20min, filter and obtain extracting solution, extracting solution, at 60 DEG C of decompression recycling ethanols, obtains naphtha 1.58.g, yield 7.9%.
Embodiment 13
Get ginger medicinal material 20g, add 200ml95% ethanol, under 400Mpa uht conditions, extract 20min, filter and obtain extracting solution, extracting solution, at 60 DEG C of decompression recycling ethanols, obtains naphtha 0.96.g, yield 4.8%.
Embodiment 14
Get turmeric medicinal material 20g, add 200ml95% ethanol, under 400Mpa uht conditions, extract 20min, filter and obtain extracting solution, extracting solution, at 60 DEG C of decompression recycling ethanols, obtains naphtha 0.88.g, yield 4.4%.
Embodiment 15
Get rhizoma atractylodis medicinal material 20g, add 200ml95% methyl alcohol, under 400Mpa uht conditions, extract 20min, filter and obtain extracting solution, extracting solution, at 60 DEG C of reclaim under reduced pressure methyl alcohol, obtains naphtha 2.76.g, yield 13.8%.
Embodiment 16
Get rhizoma atractylodis medicinal material 20g, add 200ml propyl carbinol, under 400Mpa uht conditions, extract 20min, filter and obtain extracting solution, extracting solution, at 60 DEG C of reclaim under reduced pressure propyl carbinols, obtains naphtha 2.55.g, yield 12.75%..
Embodiment 17
Get rhizoma atractylodis medicinal material 20g, add 200ml ethyl acetate, under 400Mpa uht conditions, extract 20min, filter and obtain extracting solution, extracting solution, 60 DEG C of reclaim under reduced pressure ethyl acetate, obtains naphtha 2.14g, yield 10.7%..
Embodiment 18
Get rhizoma atractylodis medicinal material 20g, add 20ml95% methyl alcohol, under 100Mpa uht conditions, extract 1min, filter and obtain extracting solution, extracting solution, at 30 DEG C of reclaim under reduced pressure methyl alcohol, obtains naphtha 0.21g, yield 1.05%.
Embodiment 19
Get rhizoma atractylodis medicinal material 20g, add 1200ml dehydrated alcohol, under 1000Mpa uht conditions, extract 30min, filter and obtain extracting solution, extracting solution, at 90 DEG C of decompression recycling ethanols, obtains naphtha 2.56g, yield 12.8%.
Embodiment 20
Get rhizoma atractylodis medicinal material 20g, add 100ml95% ethanol, under 200Mpa uht conditions, extract 3min, filter and obtain extracting solution, extracting solution, at 40 DEG C of decompression recycling ethanols, obtains naphtha 0.92g, yield 7.3%.
Embodiment 21
Get rhizoma atractylodis medicinal material 20g, add 500ml80% ethanol, under 800Mpa uht conditions, extract 5min, filter and obtain extracting solution, extracting solution, at 65 DEG C of decompression recycling ethanols, obtains naphtha 2.06g, yield 10.3%..
Embodiment 22
Get oriental wormwood punt-pole 20g, add 1000ml90% ethanol, under 500Mpa uht conditions, extract 10min, filter and obtain extracting solution, extracting solution, at 60 DEG C of decompression recycling ethanols, obtains naphtha 1.52g, yield 7.6%.
Embodiment 23
Get coriander 20g, add 1200ml40% ethanol, under 400Mpa uht conditions, extract 10min, filter and obtain extracting solution, extracting solution, at 60 DEG C of decompression recycling ethanols, obtains naphtha 0.77g, yield 3.85%.
Embodiment 24
Get purple perilla medicinal material 20g, add 200ml95% ethanol, under 400Mpa uht conditions, extract 10min, filter and obtain extracting solution, extracting solution, at 60 DEG C of decompression recycling ethanols, obtains naphtha 0.59g, yield 2.95%.
Embodiment 25
Get wrinkled giant hyssop medicinal material 20g, add 200ml95% ethanol, under 400Mpa uht conditions, extract 10min, filter and obtain extracting solution, extracting solution, at 60 DEG C of decompression recycling ethanols, obtains naphtha 1.34g, yield 6.7%.
Embodiment 26
Get fennel medicinal material 20g, add 200ml95% ethanol, under 400Mpa uht conditions, extract 10min, filter and obtain extracting solution, extracting solution, at 60 DEG C of decompression recycling ethanols, obtains naphtha 1.72g, yield 8.6%.
Embodiment 27
Get dalbergia wood medicinal material 20g, add 200ml95% ethanol, under 400Mpa uht conditions, extract 10min, filter and obtain extracting solution, extracting solution, at 60 DEG C of decompression recycling ethanols, obtains naphtha 0.90g, yield 4.5%.
Embodiment 28
Get anistree medicinal material 20g, add 200ml95% ethanol, under 400Mpa uht conditions, extract 10min, filter and obtain extracting solution, extracting solution, at 60 DEG C of decompression recycling ethanols, obtains naphtha 1.82g, yield 9.1%.
Embodiment 29
Get Rhizome of Grass leaf Sweelflag medicinal material 20g, add 200ml95% ethanol, under 400Mpa uht conditions, extract 10min, filter and obtain extracting solution, extracting solution, at 60 DEG C of decompression recycling ethanols, obtains naphtha 1.10.g, yield 5.5%.
Claims (9)
1. a method for high efficiency extraction naphtha, is characterized in that, comprises the following steps:
Step 1, gets the plant material that contains volatile oil, is processed into piece or particle;
Step 2, extracts with solvent plant material to step 1 under uht conditions;
Step 3, separates solvent and volatile oil, obtains volatile oil;
Wherein, plant material described in step 1 is processed into piece or particle and refers to and include but not limited to it to carry out cutting, fragmentation or pulverization process, is processed into if desired powder to increase surface-area;
Wherein, solvent described in step 2 is selected from any solvent that can dissolve traditional medicine volatile oil; The consumption of described solvent is 1-60 times of volume of Chinese medicinal materials weight; Described uht conditions is that in the time extracting, needing control pressure scope is 100～1000Mpa; The time length that ultra-high voltage extracts is 1-30 minute;
Wherein, separation solvent and the volatile oil described in step 3, the method for employing normal pressure or underpressure distillation.
2. according to the method for claim 1, it is characterized in that,
Wherein, plant material described in step 1, includes but not limited to the plant that Labiatae, pulse family, Illiciaceae, Araeceae, umbelliferae, composite family, Rutaceae, Lauraceae, Zingiber etc. contain volatile oil;
Wherein, solvent described in step 2 is selected from the organic solvent of solubilized volatile oil, include but not limited to ethanol, methyl alcohol, ether, dithiocarbonic anhydride, chloroform, ethyl acetate, propyl carbinol, sherwood oil, normal hexane and their mixture and the aqueous solution thereof, the consumption of described solvent is 5～25 times of volumes of Chinese medicinal materials weight, and when extraction, needing control pressure scope is 200～800Mpa; The time length that ultra-high voltage extracts is 3～20 minutes.
3. according to the method for claim 1, it is characterized in that,
Wherein, solvent described in step 2 is selected from ethanol or ethanolic soln, and in the time extracting, needing control pressure scope is 400～600Mpa; The time length that ultra-high voltage extracts is 5～10 minutes;
Separation solvent and volatile oil described in step 3, adopts distillation under vacuum, and still-process control temperature is at 30～90 DEG C, and preferably 40～80 DEG C, more preferably 50～65 DEG C.
4. the method as described in claim 1-3 any one, it is characterized in that, described in step 1, Chinese medicinal materials is selected from: the oil-containing positions such as peppermint, purple perilla, wrinkled giant hyssop, dalbergia wood, anise, Rhizome of Grass leaf Sweelflag, fennel, Radix Angelicae Sinensis, coriander, the root of Dahurain angelica, Ligusticum wallichii, tarragon, oriental wormwood punt-pole, rhizoma atractylodis, the bighead atractylodes rhizome, the banksia rose, orange, tangerine, Chinese prickly ash, camphor tree, Chinese cassia tree, ginger, turmeric, root tuber of aromatic turmeric.
5. according to the method described in claim 1-3 any one, it is characterized in that, wherein, solvent described in step 2 is selected from 40%～100% ethanol.
6. according to the method for claim 1-3 any one, it is characterized in that, wherein, solvent described in step 2 is selected from 80%～95% ethanol.
7. according to the method for claim 1, it is characterized in that, step is as follows: get rhizoma atractylodis medicinal material, 40%～100% ethanol that adds weight 1-60 times volume extracts 5-30min under 100-1000Mpa uht conditions, filters and obtains extracting solution, extracting solution, 40-90 DEG C of underpressure distillation, obtains volatile oil.
8. according to the method for claim 1, it is characterized in that, step is as follows: get rhizoma atractylodis medicinal material, 80%～95% ethanol that adds weight 5-25 times volume extracts 5-20min under 200-800Mpa uht conditions, filters and obtains extracting solution, extracting solution, 40-90 DEG C of underpressure distillation, obtains volatile oil.
9. according to the method for claim 1, it is characterized in that, step is as follows: get rhizoma atractylodis medicinal material 20g, add 200ml95% ethanol, under 400Mpa uht conditions, extract 10min, filter and obtain extracting solution, extracting solution, 60 DEG C of underpressure distillation, obtains Rhzoma Atractylodis Lanceae volatile oil crude product.
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