CN104095783A - Traditional Chinese medicine antiphlogistic and acne-removing beauty cream and preparation method thereof - Google Patents
Traditional Chinese medicine antiphlogistic and acne-removing beauty cream and preparation method thereof Download PDFInfo
- Publication number
- CN104095783A CN104095783A CN201410292438.1A CN201410292438A CN104095783A CN 104095783 A CN104095783 A CN 104095783A CN 201410292438 A CN201410292438 A CN 201410292438A CN 104095783 A CN104095783 A CN 104095783A
- Authority
- CN
- China
- Prior art keywords
- chinese medicine
- semen
- water
- skin
- pox
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
The invention provides a traditional Chinese medicine antiphlogistic and acne-removing beauty cream and a preparation method thereof. The traditional Chinese medicine antiphlogistic and acne-removing beauty cream is prepared from the following raw material components in parts by weight: 3-3.5 parts of acid litchi seeds, 0.6 part of semen hydnocarpi anthelmiticae, 0.6 part of walnut meat, 0.5-0.6 part of semen ricini, 0.6 part of cinnamomum camphora, 0.0375 part of colophonium, 0.3 part of wax, 0.45 part of stearic acid, 0.37-0.38 part of glycerol, 0.075 part of triethavolamine, 0.0037-0.0039 part of methylparaben, 0.0037-0.0039 part of ethylparaben, 0.0375 part of spontaneous emulsification monoglyceride, and 0.037-0.038 part of Twain-80. The beauty cream provided by the invention is natural in color, excellent in stability, delicate in texture, easy to spread, non-greasy, easy to wash off, free of irritation to skin, and good in release property, and can increase skin elasticity and reduce pigmentation; the penetrability of the medicine components to skin is good; the preparation method is high in extraction rate, can effectively extract antioxidant ingredients in traditional Chinese medicine, and has better economic and social benefits.
Description
Technical field
The invention belongs to Chinese medicine and daily-use chemical industry technical field, relate to a kind of Chinese medicine antiinflammatory and pull out pox cosmetic cream and preparation method thereof.
background technology
Small pox is a lot of people's cardiopathia, and a lot of small poxs are all to have walked and come, and cannot eradicate.What does is reason on earth? in fact may also have dietary habit relevant with everybody living habit.Doctor trained in Western medicine thinks that small pox is generally because androgen secretion increases or relatively increases in body, stimulates sebaceous hyperplasia loose, and secretion oil quantity rises.The cause of disease of small pox is also relevant with some pathogenic bacterial infections in addition, and attested small pox infects relevant with propanoic acid corynebacterium acnes.This corynebacterium parasitizes in hebetic pilosebaceous unit, by the catalytic action of lipase, can be hydrolyzed and produce triglyceride and more free fatty, and these free fatties can make hair follicle and hair follicle that nonspecific inflammation reaction occurs around.Chinese medicine thinks that skin is the five internal organs " mirrors ", and the small pox of skin surface and people's the vital organs of the human body are in close relations, and traditional Chinese medical science medical research shows: although small pox is grown in skin surface, closely bound up with visceral dysfunction.The reason that causes acne is: face nose and thoracic dorsal subordinate lung, and primary disease is often hindered due to the skin by wind and heat in the lung meridian; Or because of surfeit delicious food, greasy, maror, taste intrinsic heat, damp and hot interior life, fumigates in face and forms; Or because of the body in youth, in the green, sun heat rises, and fights mutually with wind and cold, due to strongly fragrant resistance skin.In Chinese medicine, think that the cause of small pox divides multiple situation: deficiency of kidney yin, lung-heat, gastric heat, heat in blood often cause small pox to produce, in addition phlegm and blood stasis, the reasons such as disharmony of Chong and Conception Channels also can cause the appearance of some small poxs, for different " endogenous cause of ill ", to take to nurse one's health accordingly way, could fundamentally cure.
Along with the raising of people's living standard, modern is also more and more higher for beautiful pursuit, and the psychology of pursuing green cosmetics, back to nature people strengthens day by day, and natural activity cosmetics are complied with the trend that goes back to nature and people's consumer psychology.The cosmetic product that the natural product of no side effects of take is active additive and cosmetic material becomes the large focus of fine chemicals industry one, the whitening product having no side effect safely, arises at the historic moment, some Chinese herbal medicine with good whitening effect are more and more subject at present the green grass or young crops of consumer and hide, and are the themes in cosmetics " green " 2l century.At present, on the market the product of anti-acne a lot of as: anti-acne facial cleanser, Deacne pack, acne-removing liquid, anti-acne quintessence oil etc., has also developed the Chinese medicine pox product that disappears.
Chinese patent CN101229115B, cosmetics of a kind of removing acne and freckle whitening and preparation method thereof.Its formula consists of jointly refined fur seal, the Radix Angelicae Dahuricae, Radix Angelicae Sinensis, Rhizoma Typhonii, Radix Scutellariae, Semen Coicis, Cortex Phellodendri, Flos Lonicerae, Margarita powder, Rhizoma Chuanxiong, Radix Salviae Miltiorrhizae, Radix Saposhnikoviae, Semen Persicae and glycerol; Chinese drug preparation fluid extract, finished product packing.
Chinese patent CN102178791B, toxin expelling acne removing agent and preparation method thereof and using method.Be to take the method that Semen Vitis viniferae is primary raw material compatibility toxin expelling acne removing agent, Semen Vitis viniferae, dry wolfberry, Radix Glycyrrhizae Preparata powder are mixed, pulverize, stirred with 74.4%, 24.8%, 0.8% weight ratio.
Chinese patent CN1125644, the ointment of Acne treatment.The medicament of being made by the raw material of following weight proportioning: Margarita powder 1-15, Tremella powder 2-12, Camphora 5-20, Herba Menthae 10-20, Rhizoma Coptidis 1-5, Radix Et Rhizoma Rhei 1-5, Alumen 1-4, Cosan 0.2-2, Moschus 2-4, Borneolum Syntheticum 0.2-1, dexamethasone 0.1-0.8, white vaseline 20-50, ethanol 0.3-1.5.
Chinese patent CN1299699, a kind of removing whelk Chinese medicine preparation.By the Mel of 30%-50% (by weight, lower with), 15% Ganoderma powder, the Radix Salviae Miltiorrhizae powder of 15%-20%, the Cortex Moutan powder of the Radix Rehmanniae powder of 10%-15%, 5%-10%, the Rhizoma Paridis of 5%-10%, be mixed into paste.
Chinese patent CN101214199B, nano active acne-eliminating cosmetic composition, said composition comprises: the nanoemulsions that contains active component, accounts for compositions 5-45wt%; Consisting of of the nanoemulsions of active component: a) active component, be taken from wherein at least a kind of of Vitamin A fatty acid ester, vitamin C fatty acid ester, vitamin e fatty acid ester, organic acid, antiinflammatory, fat-soluble anticorrosion and bactericidal agent, aforementioned each composition and in nanoemulsions content be respectively: Vitamin A fatty acid ester is selected from Vitamin A acetate, and its content is 0.1-2.0wt%; Vitamin C fatty acid ester is selected from L-AA 2-hexyl certain herbaceous plants with big flowers four esters or the different cetylate of L-AA four, and its content is 2-25wt%; Vitamin e fatty acid ester is selected from a-tocopherol three pears acid esters or a-tocopherol acetate, and its content is 2-25wt%; Organic acid is selected from malic acid, citric acid, Azelaic Acid or salicylic acid, and its content is 2-30wt%; Fat-soluble anticorrosion and bactericidal agent is selected from the chloro-2-dihydroxy diphenyl ether of propylparaben, butoben or 2,4,4-tri-, and its content is 1-10wt%; Antiinflammatory is selected from licoflavone or a-bisabolol, and its content is 0.5-30wt%; B) emulsifying agent, is selected from hydrogenation egg lecithin or hydrogenated soy phosphatidyl choline, and its content in nanoemulsions is 1-10wt%; C) oils and fats, is selected from squalane, isopropyl palmitate, isopropyl myristate, wherein at least one of Oleum Glycines, and its content in nanoemulsions is 2-15wt%; D) stabilizing agent, is selected from wherein at least a kind of of Yoshinox BHT, butylated hydroxyanisol, propylated gallate or a-tocopherol, and its content in nanoemulsions is 0.01-0.1wt%; E) surplus is deionized water; The nanoemulsions of active component adopts following methods preparation: i adds successively active component, oils and fats, emulsifying agent and stabilizing agent in the ratio in formula in circular flask; Then ii adds ethanol and rocks dissolving, afterwards, by rotary evaporator by ethanol evaporation; Iii adds deionized water vibrations to stir until form the mixed liquor of homogeneous, i.e. elementary emulsion in proportion; The elementary emulsion that iv prepares iii step imports in high pressure homogenisers, circulation homogenizing also obtains required emulsion particle diameter, during homogenizing, pressure is 500-1500 bar, homogenizing time 10-30 minute, under the constant temperature of temperature 30-40 ℃, carry out, form the nanoemulsions of distribution homogeneous, stable particle diameter 50 nanometer to 500 nanometers; II antioxidant, is selected from wherein at least a kind of of Yoshinox BHT, butylated hydroxyanisol, propylated gallate or a-tocopherol, and its content accounts for the 0.01-0.10wt% of compositions; III thickening agent, is selected from wherein at least a kind of of HANSHENGJIAO, hydroxyethyl-cellulose, hydroxypropyl cellulose, acid hydroxy polymer, and its content accounts for the 0.1-1.0wt% of compositions; All the other are cosmetics acceptable carrier and deionized water for IV.
Chinese patent CN102949322B, a kind of effect cosmetic and preparation method thereof, is characterized in that the plant material that Camellia sinensis branch and leaf, Herba Portulacae, Fructus Momordicae stem and leaf, Drymotaenium miyoshianum (Mak.) Mak. leaf, Herba Andrographis, Cortex Phellodendri are in varing proportions extraction functional component; Tourmaline is effect raw mineral materials; Glycerol is wetting agent; Resina persicae is suspending agent; Cetearyl Fructus Canarii albi grease and Olivem 1000 are coemulsifier; Tween 80 and Arlacel-80 are emulsifying agent; Through steam distillation, colloid mill grinding and high pressure homogenizer homogenizing, obtain fine and smooth emulsion, this emulsion anti-acne is trace not, has the effect of wrinkle removing, speckle dispelling, skin moistening and whitening concurrently.
Chinese patent CN102670469B, a kind of acne-eliminating cosmetic and preparation method thereof, by weight percentage, composed of the following components: A component: deionized water 64-78%, hyaluronate sodium 0.01-0.2%, 1,3-butanediol 2-10%, AVC 0.5-1%, acrylic acid (ester) class/vinyl alcohol isodecyl acid esters cross linked polymer sodium 0.15-0.5%, triethanolamine 0.15-0.5%; B component: Mel extract 0.5-5%, LS9088:1-3%, Cortex Phellodendri extract 0.5-2.0%, hydrolysis prints banyan Cactus Flower extract 1-3%, Vitex agnus-castus Linn. extract 0.5-1.5%, sad propyl group heptyl ester 2-6%; C component: Jojoba oil 2-10%, polydimethylsiloxane 2-5%; D component: antiseptic 0.2-1%, essence 0.1-0.3%.
The above its main component of a lot of product for resolving poxes is Chinese herbal medicine, uses salubrious control oil prevention small pox to produce, and the internal medium of slowly nursing one's health skin finally reaches the object of anti-acne.The single effect of traditional speckle removing skin moistening, the easy pollution clothes of oil-soluble ointment, the shortcoming that stretchability is poor.Clean is the first step of skin protection, also be the first step of anti-pox, if just ignore or select wrong clean product from the first step, the skin problems such as fuel-displaced, corse sweat pore, small pox only can be more serious, it is more and more fragile that skin also can become, it is relatively difficult that anti-pox also can become, because the obstruction of pore also can hinder the absorption of product for resolving poxes.
Summary of the invention
The object of the invention is: the one, adopt pure natural Chinese herbal medicine acid Semen Litchi material to make, abnormal smells from the patient delicate fragrance, and non-stimulated, without anaphylaxis, make medicine energy rapid permeability to skin internal layer, promote the absorption of nutritional labeling, promote skin metabolism; The 2nd, its extraction ratio that overcomes existing preparation method existence is low, the composition of some high boiling point medicine all can not be extracted to use, the easy loss of volatile ingredient of low volatility medicine, the large deficiency of loss of effective components of medical material and provide a kind of Chinese medicine antiinflammatory to pull out pox cosmetic cream and preparation method thereof.
Technical scheme of the present invention is:
The present invention according to tcm theory with Effect of Chinese Medicine Qing except free fatty in cortex and body, suppress or to kill propanoic acid corynebacterium acnes active.Selecting can heat-clearing and toxic substances removing, eliminating carbuncle eliminating stagnation, and removing heat from blood nourishes blood, astringing to arrest bleeding, detumescence and promoting granulation, granulation promoting pain relieving, antibacterial and to kill propanoic acid corynebacterium acnes active, remove free fatty, improve microcirculation in human body, promote skin metabolism, make the rejuvenate secret recipe handed down in the family of Chinese crude drug of skin, add pure natural antioxidant content, be the natural anti-oxidation composition extracting from sour Semen Litchi simultaneously, and preparation has antiinflammatory and pulls out pox cosmetic cream.
The Chinese medicine pharmacology that the present invention adopts is:
1, sour Semen Litchi: sour Semen Litchi (Acid litchi), sour Semen Litchi is the dry mature seed of sapindaceous plant acid Fructus Litchi, another name: Li Ren, branch core, litchi core, Dali core.Sweet, the micro-hardship of its nature and flavor, warm in nature.Return liver, kidney channel, have spleen reinforcing, the liver benefiting, nourish blood, the effect of happy face.Be mainly used in treating the diseases such as colic of cold type stomachache, painful and swollen testis, gastric abscess, women's Qi stagnation abdominal pain due to blood stasis.
2, Semen Hydnocarpi: Semen Hydnocarpi (Semen Hydnocarpi Anthelmiticae), the dry kernel of Flacourtiaceae plant Semen Hydnocarpi.Another name: Semen Hydnocarpi, leprosy, anthelmintic Semen Hydnocarpi.Acrid in the mouth, hot in nature, poisonous.Return liver,spleen,kidney warp.There is detoxicating and killing parasites, dispeiling pathogenic wind and removing dampness effect.For scabies, rosacea, acne, chloasma, freckle, tinea versicolor, vitiligo, white arrange, bromhidrosis, keloid, urticaria, rhagadia manus et pedis, neurodermatitis.
3, Semen Juglandis: Semen Juglandis (Juglans regial) is the seed of juglandaceae plant Semen Juglandis, another name: semen juglandis, Semen Juglandis, Semen Juglandis.Sweet in the mouth, warm in nature, gas is warm, skin Grating, meat profit.Return lung, kidney, large intestine channel.There is temperature compensation lung kidney, Dingchuan intestine moistening effect.For soreness of the waist and knees, impotence and seminal emission, deficiency and coldness, breathe heavily cough, constipation.
4, Semen Ricini: Semen Ricini (Semen Ricini) is the seed of euphorbia plant Semen Ricini, another name: Bi pockmarks, Semen Ricini, Semen Ricini, red Semen Ricini.Property is put down, sweet in the mouth, pungent.Return large intestine, lung meridian.Have rush down lower logical stagnant, detumescence and drawing out poison effect.For constipation due to dry stool, swollen ulcer drug, sore throat, scrofula, scalds edema distension; Facial hemiparalysis, traumatic injury.
5, Camphora: Camphora (Cinnamomum camphora (L.) Presl.) another name: splendid brain, camphor, brain, oily brain, tree brain.Acrid in the mouth, hot in nature, slightly poisonous.GUIXIN warp; Spleen channel.Function: orifice opening, qi stagnation removing, ward off foul, killing parasites for relieving itching, reducing swelling and alleviating pain.Cure mainly: calentura coma, attacked by pestiferous factors are dampinged off, acute filthy disease vomiting and diarrhoea stomachache, the disturbance of lower legs due to pathogenic cold and dampness, scabies stubborn dermatitis, tinea alba, chilblain, ecthyma, burn due to hot liquid or fire, traumatic pain, toothache, wind-fire acute conjunctivitis.
6, Colophonium: Colophonium (Colophonium) another name: Colophonium, loose cream, loose fat, loose glue perfume, galbanum, loose glue, Colophonium, Colophonium perfume.Bitter in the mouth, sweet, warm in nature.Return liver, spleen channel.Effect: dispel the wind, dampness, evacuation of pus, draw out pus by applying a plaster to the affected part, granulation promoting, pain relieving.Cure mainly: carbuncle, furunculosis, hemorrhoid flaccidity, malignant boil, scabies, in vain bald, incised wound, sprain, rheumatic arthralgia, leprosy pruritus.
7, Cera Flava: Cera Flava (Apis cerana Fabr) another name: Apis cerana Fabricius, wax, the sweet sole of the foot, Cera Flava, white beeswax, Huang account for.Sweet in the mouth, light, property is flat.Return spleen, stomach, large intestine channel.Effect: removing toxic substances, granulation promoting, dysentery relieving, hemostasis, analgesic therapy.Cure mainly: carbuncle carbuncle on the back, ulcer for holding back, anxious pained, dysentery pus and blood, incessant chronic diarrhea, vaginal bleeding due to excessive movement of fetus, seminal emission, leukorrhagia.
The present invention is achieved in that
Pox cosmetic cream is pulled out in a kind of Chinese medicine antiinflammatory, by following raw material components and parts by weight, made: sour Semen Litchi 3-3.5 part, 0.6 part of Semen Hydnocarpi, 0.6 part of Semen Juglandis, Semen Ricini 0.5-0.6 part, 0.6 part of Camphora, 0.0375 part of Colophonium, 0.3 part, Cera Flava, 0.45 part of stearic acid, glycerol 0.37-0.38 part, 0.075 part of triethanolamine, methyl hydroxybenzoate 0.0037-0.0039 part, ethyl hydroxybenzoate 0.0037-0.0039 part, 0.0375 part of self emulsifying monoglyceride, tween 80 0.037-0.038 part, deionized water adds to 7.5-8 part.
Pox cosmetic cream is pulled out in above-described Chinese medicine antiinflammatory, by following raw material components and parts by weight, is made: 3.3 parts of sour Semen Litchis, 0.6 part of Semen Hydnocarpi, 0.6 part of Semen Juglandis, 0.6 part of Semen Ricini, 0.6 part of Camphora, 0.0375 part of Colophonium, 0.3 part, Cera Flava, 0.45 part of stearic acid, 0.375 part of glycerol, 0.075 part of triethanolamine, 0.00375 part of methyl hydroxybenzoate, 0.00375 part of ethyl hydroxybenzoate, 0.0375 part of self emulsifying monoglyceride, 0.0375 part of tween 80, deionized water adds to 7.5 parts.
The preparation method of pox cosmetic cream is pulled out in above-described Chinese medicine antiinflammatory, comprises that Effective Component of Chinese Medicine extracts, decolours and prepare Chinese medicine antiinflammatory and pull out pox cosmetic cream, and its processing step is as follows:
(1) pulverize: the Chinese medicine powder that medicinal pulverizer in sour Semen Litchi was ground into 40 mesh sieves is standby;
(2) oil expression: by Semen Hydnocarpi, Semen Juglandis, the oil expression of Semen Ricini oil expression method routinely, the oils and fats of getting each gained is standby;
(3) alcohol extraction: sour Semen Litchi Chinese medicine coarse powder is doubly measured to 50% ethanol water immersion 15-25 minute with 15-20, then extracted active component by microwave method from Chinese medicine coarse powder, once filter, a time concentrating under reduced pressure obtains extractum, reclaims ethanol; Then with water saturated n-butyl alcohol, dissolve extractum, secondary filter, secondary concentrating under reduced pressure, makes clear paste, reclaims n-butyl alcohol;
(4) decolouring: the oils and fats of the clear paste of Camphora, Colophonium, Cera Flava, (3) step, (2) step is doubly measured to 40 ℃ of dissolving of 70% ethanol water heating, diluted with 2-3, add again active carbon to stir decolouring, the mass ratio at every turn adding is 1:0.5, divide three decolourings, can obtain the oil of clarification substantially, more separated fuel-displaced, filter for three times, three concentrating under reduced pressure, obtain proportion 1.10-1.20 cream state Effective Component of Chinese Medicine, respectively recovered carbon and ethanol;
(5) emulsifying: oil and tween 80 are ground evenly, then add stearic acid, self emulsifying monoglyceride put 90 ℃ of water-bath meltings and are incubated the oil phase that 25min constantly stirs; Separately glycerol, triethanolamine, deionized water are put to the water that 90 ℃ of water bath heat preservation 25min constantly stir; Again Metagin, ethyl ester are added in water with appropriate dissolve with ethanol, emulsifying in water being added to oil phase under 75 ℃ of stirrings, 75 ℃ are incubated and stir 20min and are constantly stirred to room temperature and can obtain, its emulsifying agent substrate and Chinese medicine extract are adopted to conventional method emulsifying, and homogenizing obtains Chinese medicine antiinflammatory and pulls out pox cosmetic cream.
90 seconds above-described microwave method control times, microwave power 210-500 watt.
Advantage of the present invention and good effect:
1, product employing Chinese herbal medicine of the present invention is main material, has overcome the single effect of traditional speckle removing skin moistening, the easy pollution clothes of oil-soluble ointment, and the shortcoming that stretchability is poor, and also have antidotal effect.Aging is that harmful attack of radical pair cell component causes, traditional chemosynthesis antioxidant has certain side effect and carcinogenecity, the sour Semen Litchi extract of this product shows stronger removing free radical ability, a kind of good Natural antioxidant and free radical scavenger, dispelling speckle simultaneously, to free radical resisting, and promote collagen protein to generate, effectively slow down aging.And outward appearance is good, color and luster nature, denseness is moderate, heat-resisting cold-resistant, good stability, exquisite quality, is easy to painting exhibition, and non-greasy is also easy to eccysis, and to skin nonirritant, release performance is good, and the paste-forming rate of medicine is high and good to the penetration performance of skin.Increase skin elasticity, alleviate Pigmented effect.
2, the present invention adopts effective pharmaceutical preparation to make medicine gather skin activity position to reach the key that onset concentration is this product research.This preparation has adopted the method for the optimum extraction process of flavone compound in microwave extraction acid Semen Litchi, microwave extraction thing specific heat is invaded extract, reflux, extract, thing is all strong to lipid-antioxidant activity effect, extraction ratio is high, can effectively extract antioxidant content in Chinese medicine, improve the function of Chinese medicine, utilize optimization process to carry out the preparation of emulsifying agent substrate simultaneously, both effects of the eliminating spots and moisturizing skin that reaches good that are combined, and save the limited and high natural resources of Chinese medicinal materials of valency.
3, this method Optimizing Technical is applied in actual production, and simple, easy row, favorable reproducibility, have good economic benefit and social benefit.
The specific embodiment
Below in conjunction with embodiment, the present invention is described in further detail, listed embodiment is only the present invention is described and is never limited to the present invention.
one, product Preparation Example
embodiment 1
(1) Chinese prescription:
3.3 kilograms of acid Semen Litchis, 0.6 kilogram of Semen Hydnocarpi, 0.6 kilogram of Semen Juglandis, 0.6 kilogram of Semen Ricini, 0.6 kilogram of Camphora, 0.0375 kilogram of Colophonium, 0.3 kilogram, Cera Flava, 0.45 kilogram of stearic acid, 0.375 kilogram of glycerol, 0.075 kilogram of triethanolamine, each 0.00375 kilogram of Metagin, ethyl ester, 0.0375 kilogram of self emulsifying monoglyceride, 0.0375 kilogram of tween 80, deionized water adds to 7.5 kilograms.
(2) preparation method:
Sour Semen Litchi is ground into 40 order Chinese medicine coarse powder with pulverizer, coarse powder is carried out to microwave extraction with 50% ethanol, material ratio is 1:20, soak 15 minutes, 212.1 watts of microwave powers, extraction time is 90 seconds, and the filtrate filtered while hot obtaining is removed filtering residue and filtrate put to temperature 70 C and carry out vacuum concentration and obtain Chinese medicine extract.Once filter, one time concentrating under reduced pressure obtains proportion 1.10 extractum, reclaims ethanol; Then with water saturated n-butyl alcohol, dissolve extractum, secondary filter, secondary concentrating under reduced pressure, makes clear paste, reclaims n-butyl alcohol.By Camphora, Colophonium, the clear paste that makes, the oils and fats simultaneously Semen Hydnocarpi, Semen Juglandis, Semen Ricini being squeezed mixes, 40 ℃ of dissolvings of ethanol water heating, dilution by 2 times of amounts 70%, add again active carbon to stir decolouring, the mass ratio at every turn adding is 1:0.5, divide three decolourings, can obtain the oil of clarification substantially.Separated fuel-displaced again, filter for three times, three concentrating under reduced pressure, the medicine that obtains proportion 1.20 cream states is oily.Cera Flava heating is dissolved, filter, add that the medicine oil of the above cream state making and tween 80 grind after dispersed and add Camphora, Colophonium, Cera Flava, stearic acid, the self emulsifying monoglyceride of prescription amount put 90 ℃ of water-bath meltings and are incubated the oil phase that 25min constantly stirs.Separately glycerol, triethanolamine, deionized water are put to the water that 90 ℃ of water bath heat preservation 25min constantly stir.Metagin, ethyl ester add in water with appropriate dissolve with ethanol.Under 75 ℃ of stirrings, water is added to emulsifying in oil phase, 75 ℃ are incubated and stir 20min and are constantly stirred to room temperature and can obtain.Its emulsifying agent substrate and Chinese medicine extract are adopted to preparation method emulsifying, and homogenizing, obtains natural freckle-diminishing skin lotion.
embodiment 2
(1) Chinese prescription:
3.5 kilograms of acid Semen Litchis, 0.6 kilogram of Semen Hydnocarpi, 0.6 kilogram of Semen Juglandis, 0.6 kilogram of Semen Ricini, 0.6 kilogram of Camphora, 0.0375 kilogram of Colophonium, 0.3 kilogram, Cera Flava, 0.45 kilogram of stearic acid, 0.375 kilogram of glycerol, 0.075 kilogram of triethanolamine, each 0.00375 kilogram of Metagin, ethyl ester, 0.0375 kilogram of self emulsifying monoglyceride, 0.0375 kilogram of tween 80, deionized water adds to 7.5 kilograms.
(2) preparation method:
Sour Semen Litchi is ground into 40 order Chinese medicine coarse powder with pulverizer, coarse powder is carried out to microwave extraction with 50% ethanol, material ratio is 1:15, soaks 212.1 watts of microwave powers 20 minutes, extraction time is 90 seconds, the filtrate filtered while hot obtaining, removes filtering residue and filtrate is put to temperature 70 C and carry out vacuum concentration and obtain Chinese medicine extract, once filters, one time concentrating under reduced pressure obtains proportion 1.15 extractum, reclaims ethanol; Then with water saturated n-butyl alcohol, dissolve extractum, secondary filter, secondary concentrating under reduced pressure, makes clear paste, reclaims n-butyl alcohol.By Camphora, Colophonium, Cera Flava, the clear paste that makes, the oils and fats simultaneously Semen Hydnocarpi, Semen Juglandis, Semen Ricini being squeezed mixes, 40 ℃ of dissolvings of ethanol water heating, dilution by 3 times of amounts 70%, add again active carbon to stir decolouring, the mass ratio at every turn adding is 1:0.5, divide three decolourings, can obtain the oil of clarification substantially.Separated fuel-displaced again, filter for three times, three concentrating under reduced pressure, the medicine that obtains proportion 1.15 cream states is oily.Cera Flava heating is dissolved, filter, add that the medicine oil of the above cream state making and tween 80 grind after dispersed and add Camphora, Colophonium, Cera Flava, stearic acid, the self emulsifying monoglyceride of prescription amount put 90 ℃ of water-bath meltings and are incubated the oil phase that 25min constantly stirs.Separately glycerol, triethanolamine, deionized water are put to the water that 90 ℃ of water bath heat preservation 25min constantly stir.Metagin, ethyl ester add in water with appropriate dissolve with ethanol.Under 75 ℃ of stirrings, water is added to emulsifying in oil phase, 75 ℃ are incubated and stir 20min and are constantly stirred to room temperature, and homogenizing, obtains natural freckle-diminishing skin lotion.
embodiment 3
(1) Chinese prescription:
3 kilograms of acid Semen Litchis, 0.5 kilogram of Semen Hydnocarpi, 0.6 kilogram of Semen Juglandis, 0.6 kilogram of Semen Ricini, 0.6 kilogram of Camphora, 0.0375 kilogram of Colophonium, 0.3 kilogram, Cera Flava, 0.45 kilogram of stearic acid, 0.38 kilogram of glycerol, 0.075 kilogram of triethanolamine, each 0.0037 kilogram of Metagin, ethyl ester, 0.039 kilogram of self emulsifying monoglyceride, 0.038 kilogram of tween 80, deionized water adds to 8 kilograms.
(2) preparation method:
Sour Semen Litchi is ground into 40 order Chinese medicine coarse powder with pulverizer, coarse powder is carried out to microwave extraction with 50% ethanol, material ratio is 1: 15, soaks 212.1 watts of microwave powers 25 minutes, extraction time is 90 seconds, the filtrate filtered while hot obtaining, removes filtering residue and filtrate is put to temperature 70 C and carry out vacuum concentration and obtain Chinese medicine extract, once filters, one time concentrating under reduced pressure obtains proportion 1.20 extractum, reclaims ethanol; Then with water saturated n-butyl alcohol, dissolve extractum, secondary filter, secondary concentrating under reduced pressure, makes clear paste, reclaims n-butyl alcohol.By Camphora, Colophonium, the clear paste that makes, the oils and fats simultaneously Semen Hydnocarpi, Semen Juglandis, Semen Ricini being squeezed mixes, 40 ℃ of dissolvings of ethanol water heating, dilution by 2.5 times of amounts 70%, add again active carbon to stir decolouring, the mass ratio at every turn adding is 1:0.5, divide three decolourings, can obtain the oil of clarification substantially.Separated fuel-displaced again, filter for three times, three concentrating under reduced pressure, the medicine that obtains proportion 1.20 cream states is oily.Cera Flava heating is dissolved, filter, add that the medicine oil of the above cream state making and tween 80 grind after dispersed and add Camphora, Colophonium, Cera Flava, stearic acid, the self emulsifying monoglyceride of prescription amount put 90 ℃ of water-bath meltings and are incubated the oil phase that 25min constantly stirs.Separately glycerol, triethanolamine, deionized water are put to the water that 90 ℃ of water bath heat preservation 25min constantly stir.Metagin, ethyl ester add in water with appropriate dissolve with ethanol.Under 75 ℃ of stirrings, water is added to emulsifying in oil phase, 75 ℃ are incubated and stir 20min and are constantly stirred to room temperature, can obtain homogenizing, obtain natural freckle-diminishing skin lotion.
two, application example
1, king X X, women, the age: 26, occupation: the civilian of capital company.Skin symptom: small pox, redness, have pustule, use before this product: small pox is intensive, have redness.Use the present embodiment 1 product, take smearing on the face for early, middle and late three times every day, smear especially for small pox, together with the repeated multiple times wiping examination in red and swollen position, increase frost amount, within 5 days, pain alleviates, and red and swollen small pox surface is shrivelled; Within 20 days, small pox has obtained preliminary inhibition, slowly reduces, and small pox epidermis knot eggplant comes off, and pox prints thin out gradually; Adhere to being inhibited by 45 days small poxs, pox prints most of disappearance, and skin is gradually smoothly pale, ruddy gloss.
2, Wei X X, male, the age: 26, occupation: business administration.Skin symptom: corse sweat pore, oils and fats is vigorous, and face has large area small pox, and the long blackhead in nose both sides, before use, is had one's face covered with glossy, with congestion and swelling pain.Use the present embodiment 2 products, respectively smear one time 30 minutes every day sooner or later, and after three days, congestion and swelling pain is felt to alleviate; After eight days, small pox, acne start atrophy, and facial oiliness reduces; Within 14 days, blackhead comes off, and red and swollen disappearance pain does not have completely; Glossy elimination after 21 days, pox prints desalination; Fine and smooth level and smooth with 49 days skin pores continuously, pox prints seamless, glossy disappearance, and blackhead, small pox are again without recurrence, and small pox has obtained effectively suppressing.
3, land X X: women, 29 years old age, occupation: the teacher of middle school.Skin symptom: skin of face is dry, without smooth, nonelastic, there are comedo and macula lutea.Warm water cleaning every night face is wiped the present embodiment 2 products again, starts one week without significant change; Within two weeks, rear face skin improves, and colour of skin gain color recovers elasticity, and comedo growth population is inhibited; Use surrounding sky face skin vitality to strengthen, xerosis cutis sense improves, and macula lutea reduces; Adhere to using ten weeks rear face skin to become lubricated delicate, macula lutea and comedo disappear, and skin is ruddy glossy.
4, yellow X X, male, the age: 23, occupation: student.Skin symptom: pore is larger, oils and fats is vigorous, and skin is oiliness, and the long blackhead in nose both sides, is used before this product, has one's face covered with glossy, with congestion and swelling pain.Use the present embodiment 1 product, respectively smear one time 15 minutes every day sooner or later, and after six days, pain perception alleviates obvious; After one week, small pox, acne start atrophy, and facial oiliness reduces; Within 14 days, blackhead comes off, and red and swollen disappearance pain does not have completely; Glossy elimination after three weeks, pox prints desalination; Fine and smooth level and smooth with eight weeks skin pores continuously, pox prints seamless, glossy disappearance, and blackhead, small pox are again without recurrence, and small pox has obtained effectively suppressing.
Claims (4)
1. pox cosmetic cream is pulled out in a Chinese medicine antiinflammatory, it is characterized in that: by following raw material components and parts by weight, made: sour Semen Litchi 3-3.5 part, 0.6 part of Semen Hydnocarpi, 0.6 part of Semen Juglandis, Semen Ricini 0.5-0.6 part, 0.6 part of Camphora, 0.0375 part of Colophonium, 0.3 part, Cera Flava, 0.45 part of stearic acid, glycerol 0.37-0.38 part, 0.075 part of triethanolamine, methyl hydroxybenzoate 0.0037-0.0039 part, ethyl hydroxybenzoate 0.0037-0.0039 part, 0.0375 part of self emulsifying monoglyceride, tween 80 0.037-0.038 part, deionized water adds to 7.5-8 part.
2. pox cosmetic cream is pulled out in a kind of Chinese medicine antiinflammatory according to claim 1, it is characterized in that: pox cosmetic cream is pulled out in described Chinese medicine antiinflammatory, by following raw material components and parts by weight, made: 3.3 parts of sour Semen Litchis, 0.6 part of Semen Hydnocarpi, 0.6 part of Semen Juglandis, 0.6 part of Semen Ricini, 0.6 part of Camphora, 0.0375 part of Colophonium, 0.3 part, Cera Flava, 0.45 part of stearic acid, 0.375 part of glycerol, 0.075 part of triethanolamine, 0.00375 part of methyl hydroxybenzoate, 0.00375 part of ethyl hydroxybenzoate, 0.0375 part of self emulsifying monoglyceride, 0.0375 part of tween 80, deionized water adds to 7.5 parts.
3. the preparation method that pox cosmetic cream is pulled out in a kind of Chinese medicine antiinflammatory according to claim 1 and 2, is characterized in that: comprise that Effective Component of Chinese Medicine extracts, decolours and prepare Chinese medicine antiinflammatory and pull out pox cosmetic cream, its processing step is as follows:
(1) pulverize: the Chinese medicine powder that medicinal pulverizer in sour Semen Litchi was ground into 40 mesh sieves is standby;
(2) oil expression: by Semen Hydnocarpi, Semen Juglandis, the oil expression of Semen Ricini oil expression method routinely, the oils and fats of getting each gained is standby;
(3) alcohol extraction: sour Semen Litchi Chinese medicine coarse powder is doubly measured to 50% ethanol water immersion 15-25 minute with 15-20, then extracted active component by microwave method from Chinese medicine coarse powder, once filter, a time concentrating under reduced pressure obtains extractum, reclaims ethanol; Then with water saturated n-butyl alcohol, dissolve extractum, secondary filter, secondary concentrating under reduced pressure, makes clear paste, reclaims n-butyl alcohol;
(4) decolouring: the oils and fats of the clear paste of Camphora, Colophonium, Cera Flava, (3) step, (2) step is doubly measured to 40 ℃ of dissolving of 70% ethanol water heating, diluted with 2-3, add again active carbon to stir decolouring, the mass ratio at every turn adding is 1:0.5, divide three decolourings, can obtain the oil of clarification substantially, more separated fuel-displaced, filter for three times, three concentrating under reduced pressure, obtain proportion 1.10-1.20 cream state Effective Component of Chinese Medicine, respectively recovered carbon and ethanol;
(5) emulsifying: oil and tween 80 are ground evenly, then add stearic acid, self emulsifying monoglyceride put 90 ℃ of water-bath meltings and are incubated the oil phase that 25min constantly stirs; Separately glycerol, triethanolamine, deionized water are put to the water that 90 ℃ of water bath heat preservation 25min constantly stir; Again Metagin, ethyl ester are added in water with appropriate dissolve with ethanol, emulsifying in water being added to oil phase under 75 ℃ of stirrings, 75 ℃ are incubated and stir 20min and are constantly stirred to room temperature and can obtain, its emulsifying agent substrate and Chinese medicine extract are adopted to conventional method emulsifying, and homogenizing obtains Chinese medicine antiinflammatory and pulls out pox cosmetic cream.
4. the preparation method that pox cosmetic cream is pulled out in a kind of Chinese medicine antiinflammatory according to claim 3, is characterized in that: 90 seconds described microwave method control times, microwave power 210-500 watt.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410292438.1A CN104095783A (en) | 2014-06-26 | 2014-06-26 | Traditional Chinese medicine antiphlogistic and acne-removing beauty cream and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410292438.1A CN104095783A (en) | 2014-06-26 | 2014-06-26 | Traditional Chinese medicine antiphlogistic and acne-removing beauty cream and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN104095783A true CN104095783A (en) | 2014-10-15 |
Family
ID=51664582
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410292438.1A Pending CN104095783A (en) | 2014-06-26 | 2014-06-26 | Traditional Chinese medicine antiphlogistic and acne-removing beauty cream and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104095783A (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105125469A (en) * | 2015-10-09 | 2015-12-09 | 吴优 | Multi-effect skin care product for removing acne and preparation method thereof |
| CN105919499A (en) * | 2015-06-08 | 2016-09-07 | 庄可军 | Clean closestool cushion cover provided with activated carbon filling layer |
| CN105942915A (en) * | 2015-06-08 | 2016-09-21 | 庄可军 | Closed anti-mosquito seat mat for closestool and flush closestool provided with mat |
| CN105996878A (en) * | 2015-06-08 | 2016-10-12 | 庄可军 | Multifunctional healthy home toilet paper |
| CN106983832A (en) * | 2017-06-06 | 2017-07-28 | 合肥华盖生物科技有限公司 | A kind of skin disinfectant and preparation method thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012033422A1 (en) * | 2010-09-06 | 2012-03-15 | Aleksandar Pavlov | Medical cosmetic herbal composition on the basis of herbal mixture and the procedure for its obtention |
| CN102813696A (en) * | 2012-08-27 | 2012-12-12 | 广西金海堂药业有限责任公司 | Chinese medicinal preparation treating fungus skin diseases and its preparation method |
-
2014
- 2014-06-26 CN CN201410292438.1A patent/CN104095783A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012033422A1 (en) * | 2010-09-06 | 2012-03-15 | Aleksandar Pavlov | Medical cosmetic herbal composition on the basis of herbal mixture and the procedure for its obtention |
| CN102813696A (en) * | 2012-08-27 | 2012-12-12 | 广西金海堂药业有限责任公司 | Chinese medicinal preparation treating fungus skin diseases and its preparation method |
Non-Patent Citations (11)
| Title |
|---|
| 中华人民共和国***: "《化妆品卫生规范》", 31 January 2007 * |
| 伯杰龙等: "《生物炼制产品与技术》", 31 January 2013, 上海科学技术出版社 * |
| 刘树民: "《中药药物性肝损害》", 30 September 2007, 中国中医药出版社 * |
| 汤建萍: "中药荔枝核活性成分的分离制备新工艺及其药效活性研究", 《中国博士学位论文全文数据库工程科技I辑》 * |
| 王建等: "《中药学专业知识.1》", 31 March 2014, 中国医药科技出版社 * |
| 胡元亮: "《中兽医学》", 31 December 2006, 中国农业出版社 * |
| 胡昌江等: "《中药炮制与临床应用》", 30 June 1992, 四川科学技术出版社 * |
| 董银卯等: "《本草药妆品》", 30 June 2010, 化学工业出版社 * |
| 邱汉琛等: "对广西壮药酸荔枝叶皮核化学成分预试验", 《广州化学》 * |
| 阎世翔: "《化妆品科学（下）》", 31 October 1998, 科学技术文献出版社 * |
| 陆永旺等: "酸荔枝核黄酮体外抗氧化作用的研究", 《中国酿造》 * |
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105919499A (en) * | 2015-06-08 | 2016-09-07 | 庄可军 | Clean closestool cushion cover provided with activated carbon filling layer |
| CN105942915A (en) * | 2015-06-08 | 2016-09-21 | 庄可军 | Closed anti-mosquito seat mat for closestool and flush closestool provided with mat |
| CN105996878A (en) * | 2015-06-08 | 2016-10-12 | 庄可军 | Multifunctional healthy home toilet paper |
| CN105996878B (en) * | 2015-06-08 | 2018-07-31 | 庄可军 | A kind of Multifunctional domestic health care paper pumping |
| CN105919499B (en) * | 2015-06-08 | 2018-07-31 | 庄可军 | A kind of cleaning sitting toilet sleeve gasket of active charcoal filled layer |
| CN105942915B (en) * | 2015-06-08 | 2018-08-03 | 庄可军 | A kind of water closet of closestool closed mosquito-proof cushion and the device cushion |
| CN105125469A (en) * | 2015-10-09 | 2015-12-09 | 吴优 | Multi-effect skin care product for removing acne and preparation method thereof |
| CN105125469B (en) * | 2015-10-09 | 2018-02-13 | 佛山市万盈化妆品有限公司 | A kind of multiple-effect anti-acne skin care item and preparation method thereof |
| CN106983832A (en) * | 2017-06-06 | 2017-07-28 | 合肥华盖生物科技有限公司 | A kind of skin disinfectant and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| KR101584742B1 (en) | Cosmetic composition for improving skin-aging | |
| CN103571657B (en) | A kind of natural soap except acne and preparation method thereof | |
| CN105779175A (en) | Natural handmade soap with acne removing function and preparation method of natural handmade soap | |
| KR20010000396A (en) | whiten toilet-ry | |
| CN104095783A (en) | Traditional Chinese medicine antiphlogistic and acne-removing beauty cream and preparation method thereof | |
| KR101128564B1 (en) | The manufacturing process of lithospermum erythrorhizon soap controlled by vineger | |
| US9554985B2 (en) | Agent for promoting hair growth and method for preparing same | |
| CN105125466A (en) | Freckle removing night cream and preparing method thereof | |
| CN109248194A (en) | A kind of essential oil composition and its preparation for treating tinea pedis | |
| CN114146014B (en) | Compound menthyl nicotinate plant polysaccharide emulsifiable paste and preparation method thereof | |
| CN105853297A (en) | Oil-control acne-prevention cosmetic containing cedrela sinensis extract and preparing method of oil-control acne-prevention cosmetic | |
| KR20140145278A (en) | Cosmetic composition containing Cimicifuga heracleifolia extract, Cornus officinalis extract and Geranium nepalense extract for skin convergence and elasticity effect | |
| CN104434609A (en) | Compound traditional Chinese medicine extract with acne removing function and application thereof in cosmetics | |
| CN102670479B (en) | Traditional Chinese medicine antiphlogistic acne-pullout cosmetic cream and preparation method thereof | |
| CN105213279A (en) | A kind of body lotion eliminating striae atrophicae and preparation method thereof | |
| CN103191328B (en) | Acne removing cream | |
| KR102049208B1 (en) | Cosmetic composition for reducing acne and inhibiting sebum secretion | |
| CN106667852A (en) | Traditional Chinese medicine cream for removing acne and preparation method thereof | |
| CN105342966A (en) | Skin care moisturizer containing hirudo nipponia and preparation method of skin care moisturizer | |
| CN111040896A (en) | Antibacterial, anti-inflammatory and skin-beautifying handmade soap | |
| KR101183893B1 (en) | Cosmetic composition having improving ability for atopy dermatitis and method for using the same | |
| KR20160003920A (en) | Cosmetic composition for anti-inflammation or improving skin trouble containing herb extracts | |
| CN101229258B (en) | Antianaphylaxis antiphlogistin | |
| CN103920124B (en) | A kind of sterilizing skin-protective kibe ointment | |
| CN106727051A (en) | A kind of Chinese medicine anti-acne elite and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20141015 |
|
| WD01 | Invention patent application deemed withdrawn after publication |