CN102813696A - Chinese medicinal preparation treating fungus skin diseases and its preparation method - Google Patents

Abstract

The invention discloses a Chinese medicinal preparation treating fungus skin diseases. The Chinese medicinal preparation is prepared from the following main raw materials by weight: 8-12 parts of chaulmoogra oil, 8-12 parts of walnut oil, 8-12 parts of castor oil, 30-40 parts of sesame oil, 7.5-12.5 parts of beeswax, 0.5-1.5 parts of rosin, 45-55 parts of camphor, 20-30 parts of Hydrargyri Oxydum Rubrum, and 140-155 parts of Vaseline. The preparation method consists of: subjecting the raw materials to heating melting, cooling and mixing, then conducting grinding and subpackaging, thus obtaining the ointment preparation. The product of the invention has the characteristics of wide raw material sources, low cost, as well as simple preparation process, has the efficacy of eliminating macules, drying dampness, and promoting blood circulation, and can treat various tinea, acne, pimples, acne rosacea, freckles, sweat stains, vitiligo, damp toxin and beriberi.

Description

A kind of Chinese medicine preparation of treating dermatomycosis and preparation method thereof

Technical field

The present invention relates to a kind of treatment dermatomycosis, just Chinese medicine preparation of the said skin skin ulcer of traditional Chinese medical science tinea class, acne pimple, vinasse acne rosacea, freckle tinea versicolor, vitiligo, damp beriberi and preparation method thereof.

Background technology

Dermatomycosis, just symptoms such as the said tinea pedis of people, tinea pedis, tinea corporis, tinea capitis, acne, coppernose, vitiligo in all age all belong to frequently-occurring disease, commonly encountered diseases; Some tinea class is quite obstinate, and long-term treatment is not felt any better, and very itches and feels bad; Influence sleep and work, the dermatosis patient that has especially again and again, touching difficulty is more; Not only influence its quality of life, and be prone to spread and infect other people.Theory of Chinese medical science thinks because nutrient blood loss, and it is dry to give birth to air slaking, and skin loses that reason such as neat causes.It is relevant with fungal infection that modern study is thought.Simultaneously also with to lack trace element such as zinc, ferrum, lead relevant in the body.

For the Therapeutic Principle of dermatomycosis, be that it is main invigorating blood circulation antipruritic with parasite killing treatment tinea, dampness.The traditional Chinese medical science is represented Fang You: arsenicum looses: card is controlled accurate strong side.Prescription arsenicum, sulfur, Lithargyrum, greasy powder are imitated merit and are controlled dried, wet all tinea.(Chinese medicine voluminous dictionary).The well-known doctor Zhang Xichun of the Qing Dynasty compiles " Records of Tradition Chinese and Western Medicine in Combination " to be had: Semen Hydnocarpi, arsenicum sablimatum, control the stubborn dermatitis record.Also have the various traditional Chinese medical science or Western medicine tinea liquid, ointment to sell at present on the market, certain curative effect is arranged, but to some stubborn dermatitis, the long-term tinea class that does not heal, adaptability is wideless, effect is relatively poor, and some is invalid.

Summary of the invention

Technical problem to be solved by this invention provides Chinese medicine preparation of a kind of evident in efficacy, easy to use, wide adaptability, moderate treatment dermatomycosis and preparation method thereof.

The present invention solves the problems of the technologies described above with following technical scheme:

The present invention treats the Chinese medicine preparation of dermatomycosis, it be by following raw materials in portion by weight through the fusing of heating, cooling mixes, the ointment formulation of processing through grinding, packing then:

8～12 parts of chaulmoogra oils, 8～12 parts of walnut oils, 8～12 parts of Oleum Ricini, 30～40 parts in Oleum Sesami, 7.5～12.5 parts in Cera Flava, 0.5～1.5 part of Colophonium, 45～55 parts of Camphoras, 20～30 parts in Hydrargyri Oxydum Rubrum, 140 ~ 155 parts in vaseline.

The preferred version of above-mentioned raw materials prescription is:

10 parts of chaulmoogra oils, 10 parts of walnut oils, 10 parts of Oleum Ricini, 35 parts in Oleum Sesami, 10 parts in Cera Flava, 1 part of Colophonium, 50 parts of Camphoras, 25 parts in Hydrargyri Oxydum Rubrum, 150 parts in vaseline.

The preparation technology that preparation the present invention treats the Chinese medicine preparation of dermatomycosis is:

Get chaulmoogra oil, walnut oil, Oleum Ricini, Oleum Sesami and be heated to 180～200 ℃, add Cera Flava, Colophonium and vaseline fusing, in 160～180 ℃ of insulations 15 minutes; Be cooled to 130～140 ℃ and add Hydrargyri Oxydum Rubrum, temperature camphorates when reducing to 60～70 ℃, stirs; When being chilled to 30～40 ℃, after the colloid mill grinding, packing; Seal, promptly obtain finished product.

The present invention adopts comparatively characteristic Chinese crude drugs of seeing as raw material more, and by the theoretical formulated ointment formulation of strong medicine, preparation technology is simple, and production cost is low, is suitable for large-scale production on the modern enterprise.

The use and the points for attention of product of the present invention are:

Product of the present invention belongs to medicine for external use; The effect of speckle removing, dampness are arranged, invigorating blood circulation can be treated various tinea classes, acne pimple, vinasse acne rosacea, freckle, tinea versicolor, vitiligo, damp beriberi, and stubborn dermatitis is also had significant curative effect; Wipe the affected part 2-3 every day, and the time of a course of treatment is 7 days.Because the Chinese crude drug that has is poisonous, can not take orally, there is allergy sufferers to stop using.

The specific embodiment

The attribute and the effect of raw material are following in the present invention's prescription:

Chaulmoogra oil: the fatty oil that obtains with milling process for the mature seed of the aiphyllium Semen Hydnocarpi Hydnocarpus anthelmintica Pierre. of Semen Hydnocarpi section.The property hot, hot.Very toxic.Return the liver,spleen,kidney warp.There carminative dampness, killing insects attack the efficacy of the product Singery toxic, mainly used outside of clinical.Diseases such as treatment scabies, suitable amount used externally.

Oleum Ricini: the fatty oil that obtains with milling process for the mature seed of euphorbia plant Semen Ricini Ricinus communis L..Property is sweet, hot.Poisonous.Return large intestine, lung meridian.Have to rush down and lead to effect stagnant, detumescence and drawing out poison down, be used for constipation due to dry stool, swollen ulcer drug, sore throat, scrofula, suitable amount used externally.

Walnut oil: the fatty oil that obtains with milling process for the dry mature seed of juglandaceae plant Semen Juglandis Juglans regia L..Property is sweet, warm, returns kidney, lung, large intestine channel.The effect that the kidney invigorating, warming the lung, intestine moistening are arranged, be used for insufficiency of kidney-YANG, soreness of the waist and knees, impotence and seminal emission, deficiency and coldness breathe heavily cough, the treatment of dryness of the intestine constipation.

Cera Flava: be Apidae insecticide apis cerana Apis cerana FabriciuS or the excretory wax of apis mellifera Linnaeus APis mellifera Linnaeus.Sweet, the tepor of property.Return spleen channel.Detoxifcation arranged, hold back skin ulcer, granulation promoting, analgesic effect.Be used for ulcer being unable to heal, rotten to the corn, the burn and scald of ecthyma outward.Suitable amount used externally.

Colophonium: be the oleoresin of obtaining in pinaceae plant Pinus massoniana Lamb or its congener trunk, the legacy after volatile oil is removed in distillation.Property is sweet, warm.Return liver, spleen channel.Dispel the wind, dampness, evacuation of pus, draw out pus by applying a plaster to the affected part, granulation promoting, analgesic effect.Be used for carbuncle, furunculosis, hemorrhoid complicated by anal fistula, malignant boil, scabies, bald in vain, incised wound is sprained, rheumatic arthralgia, leprosy pruritus.Many externals are ground into powder and are spread or transfer deposited.

Hydrargyri Oxydum Rubrum: be hydrargyri oxidum rubrum (HgO), minerals as Chinese medicine.The property hot, hot, very toxic.Return lung, spleen channel.Have draw out pus by applying a plaster to the affected part, remove, the effect of removing the necrotic tissue, granulation promoting.Be used for the carbuncle furuncle, syphilitic chancre, all malignant boil, meat is dark violet black, and slough does not go, the sinus tract fistula, pus is dripping, does not close up for a long time.Suitable amount used externally.These article are poisonous, external only, and oral administration not, external also can not be used for a long time, anemia of pregnant woman's forbidding.

Camphora: be root, the branch and leaf of the plant Lignum cinnamomi camphorae Cinnanomum Camphora of Lignum cinnamomi camphorae section (L.) presl., the crystalline particulate of distillation gained.Sensible, parasite killing, pain relieving are arranged, ward off dirty effect, be used for diseases such as trusted subordinate's distending pain, beriberi, skin infection, scabies.

Oleum Sesami: the fatty oil that obtains with milling process for the mature seed of Pedaliaceae plant sesame Sesamum indicum L..Sweet in the mouth, property are flat, nontoxic; The effect that moistening dryness for relaxing bowels, nourishing blood to expel wind, detoxifcation, granulation promoting are arranged is used for the dryness of the intestine constipation, ascarid, abdominal pain due to retention of food, and skin ulcer is swollen, ulcer, scabies, diseases such as chapped skin.For wrinkle, black speck, scaly dry skin etc. inhibitory action is arranged.

Embodiment 1:

Composition of raw materials: chaulmoogra oil 10kg, walnut oil 10kg, Oleum Ricini 10kg, Oleum Sesami 35kg, Cera Flava 10kg, Colophonium 1kg, Camphora 50kg, Hydrargyri Oxydum Rubrum 25kg, vaseline 150kg.

Preparation technology: get chaulmoogra oil, walnut oil, Oleum Ricini, Oleum Sesami and put into heating tank, be heated to 180 ℃, add Cera Flava, Colophonium and vaseline fusing; 160 ℃ are incubated 15 minutes, are cooled to 130 ℃ and add Hydrargyri Oxydum Rubrum, and temperature camphorates when reducing to 60 ℃; Ceaselessly stir, when being chilled to 40 ℃, be ground to 250 mesh sieves with colloid mill after; Packing is sealed, and promptly obtains finished product.

Embodiment 2:

Composition of raw materials: chaulmoogra oil 12kg, walnut oil 8kg, Oleum Ricini 12kg, Oleum Sesami 33kg, Cera Flava 12kg, Colophonium 1kg, Camphora 46kg, Hydrargyri Oxydum Rubrum 27kg, vaseline 155kg.

Preparation technology: get chaulmoogra oil, walnut oil, Oleum Ricini, Oleum Sesami and put into heating tank, be heated to 190 ℃, add Cera Flava, Colophonium and vaseline fusing; 170 ℃ are incubated 15 minutes, are cooled to 135 ℃ and add Hydrargyri Oxydum Rubrum, and temperature camphorates when reducing to 65 ℃; Ceaselessly stir, when being chilled to 35 ℃, be ground to 250 mesh sieves with colloid mill after; Packing is sealed, and promptly obtains finished product.

Embodiment 3:

Composition of raw materials: chaulmoogra oil 8kg, walnut oil 12kg, Oleum Ricini 8kg, Oleum Sesami 37kg, Cera Flava 8kg, Colophonium 0.5kg, Camphora 54kg, Hydrargyri Oxydum Rubrum 23kg, vaseline 140kg.

Preparation technology: get chaulmoogra oil, walnut oil, Oleum Ricini, Oleum Sesami and put into heating tank, be heated to 200 ℃, add Cera Flava, Colophonium and vaseline fusing; 180 ℃ are incubated 15 minutes, are cooled to 130 ℃ and add Hydrargyri Oxydum Rubrum, and temperature camphorates when reducing to 60 ℃; Ceaselessly stir, when being chilled to 35 ℃, be ground to 250 mesh sieves with colloid mill after; Packing is sealed, and promptly obtains finished product.

Embodiment 4:

Composition of raw materials: chaulmoogra oil 8kg, walnut oil 10kg, Oleum Ricini 12kg, Oleum Sesami 37kg, Cera Flava 8kg, Colophonium 1.5kg, Camphora 50kg, Hydrargyri Oxydum Rubrum 25kg, vaseline 150kg.

Preparation technology: get chaulmoogra oil, walnut oil, Oleum Ricini, Oleum Sesami and put into heating tank, be heated to 190 ℃, add Cera Flava, Colophonium and vaseline fusing; 170 ℃ are incubated 15 minutes, are cooled to 140 ℃ and add Hydrargyri Oxydum Rubrum, and temperature camphorates when reducing to 65 ℃; Ceaselessly stir, when being chilled to 30 ℃, be ground to 250 mesh sieves with colloid mill after; Packing is sealed, and promptly obtains finished product.

Below be to use the typical case of product of the present invention to verify instance:

Case one: Liu, man, 30 years old, Nanning city company personnel; Suffer from the tinea manuum for many years, there is erythema the back of the hand portion many places, and decortication is itched; Once purchased certain famous brand ointment treatment a period of time, having got well a period of time recurs again, and erythema, decortication expanded range, gives the work deleterious impact.The back is with product treatment of the present invention (the outer wiping), and 3 all backs take a turn for the better, and continue 2 weeks of treatment, and erythema, decortication scope are dwindled gradually, continue to put medicine, fully recover at last.

Case two: Zheng, man, 37 years old, people from Tianjin.Found the both legs circular annular erythema of 4.5 * 4cm2 size of having an appointment before 3 years, edge most grain of rices size pimple belongs to tinea corporis.Medication can disease controlling, and the recurrence of stopping using is not touchingly healed.The back is with product treatment of the present invention (the outer wiping), and the state of an illness is controlled after 15 days, continues treatment, and recovery from illness is followed up a case by regular visits to and do not had recurrence half a year after 28 days.

Case three: Pan, the man, 45 years old, people from Liuzhou found before 10 years that cervical region, waist and belly have white macula to occur; Smooth, no squama, no sufferings, obvious with normal colour of skin boundary, hospital diagnosis is a vitiligo, white macula is controlled after the medication; But vitiligo belongs to chronic disease, needs the long-term prescription treatment, because of the household economy difficulty, unablely undertakes higher medical expense; TD, white macula fills the air gradually and spreads, and influences appearance, feels depressed.After use product of the present invention treatment (the outer wiping) 2 months upon somebody's introduction, the white macula color is thin out, moves closer to the normal colour of skin, continues medication 3 months, at last recovery from illness.

Case four: Lee, woman, 51 years old, Earthquake of Anyang station in Henan people.Nose flushing, greasy shinny, the visible obviously dendroid blood capillary branch of naked eyes, with pruritus, scorching hot and pain, typical vinasse nose early symptom.With product treatment of the present invention (the outer wiping), the state of an illness is controlled after 20 days, continues the medication treatment, recovery from illness after 60 days.

Case five: Wang, woman, 26 years old, people from Nanning.Patient's forehead, the bridge of the nose and cheek etc. locate to occur a kind of light brown fleck, needle point to grain of rice size, and the skin quality is more black.Once used multiple cosmetic applying, all can't eliminate.Wipe outward with product of the present invention the back, and black speck after 7 days course of treatment, passeris montani saturati are thin out, and continue medication and wipe outward, black speck disappearance after three 22 days courses of treatment, colour of skin light is as before gorgeous.

Case six: Xiao, the man, 18 years old, the student liked to move, and circular point-like macule appears in chest and back, extremity near-end, clear-cut margin, the erythra surface is with the Lycoperdon polymorphum Vitt or the brown defurfuration of very easily peeling off on a small quantity, and rash is disconnected to be tinea versicolor.After give preparation of the present invention and wipe outward, recovery from illness after 3 months.

Claims (3)

1. a Chinese medicine preparation of treating dermatomycosis is characterized in that, through the fusing of heating, cooling mixes, the ointment formulation of processing through grinding, packing then by following raw materials in portion by weight for it:

8～12 parts of chaulmoogra oils, 8～12 parts of walnut oils, 8～12 parts of Oleum Ricini, 30～40 parts in Oleum Sesami, 7.5～12.5 parts in Cera Flava, 0.5～1.5 part of Colophonium, 45～55 parts of Camphoras, 20～30 parts in Hydrargyri Oxydum Rubrum, 140 ~ 155 parts in vaseline.

2. the Chinese medicine preparation of treatment dermatomycosis according to claim 1 is characterized in that, the composition of raw materials preferred version is:

10 parts of chaulmoogra oils, 10 parts of walnut oils, 10 parts of Oleum Ricini, 35 parts in Oleum Sesami, 10 parts in Cera Flava, 1 part of Colophonium, 50 parts of Camphoras, 25 parts in Hydrargyri Oxydum Rubrum, 150 parts in vaseline.

3. a method for preparing of treating the Chinese medicine preparation of dermatomycosis is characterized in that,

Required raw material is: 8～12 parts of chaulmoogra oils, 8～12 parts of walnut oils, 8～12 parts of Oleum Ricini, 30～40 parts in Oleum Sesami, 7.5～12.5 parts in Cera Flava, 0.5～1.5 part of Colophonium, 45～55 parts of Camphoras, 20～30 parts in Hydrargyri Oxydum Rubrum, 140 ~ 155 parts in vaseline;

Preparation technology is:

Get chaulmoogra oil, walnut oil, Oleum Ricini, Oleum Sesami and be heated to 180～200 ℃, add Cera Flava, Colophonium and vaseline fusing, in 160～180 ℃ of insulations 15 minutes; Be cooled to 130～140 ℃ and add Hydrargyri Oxydum Rubrum, temperature camphorates when reducing to 60～70 ℃, stirs; When being chilled to 30～40 ℃, after the colloid mill grinding, packing; Seal, promptly obtain finished product.