CN104083637A - Traditional Chinese medicine preparation for treating atrophic rhinitis - Google Patents

Abstract

A traditional Chinese medicine preparation for treating atrophic rhinitis comprises the raw materials: 15 parts of folium mori, 30 parts of radix adenophorae, 30 parts of gypsum, 12 parts of radix ophiopogonis, 12 parts of herba dendrobii, 12 parts of dondey-hide gelatin, 10 parts of bitter apricot seed, 15 parts of fructus cannabis and 10 parts of radix scutellariae. A preparation method for the traditional Chinese medicine preparation comprises: weighing 15 parts of folium mori, 30 parts of radix adenophorae, 30 parts of gypsum, 12 parts of radix ophiopogonis, 12 parts of herba dendrobii, 12 parts of dondey-hide gelatin, 10 parts of bitter apricot seed, 15 parts of fructus cannabis and 10 parts of radix scutellariae, respectively preparing decoction pieces, performing stewing sterilization for 30-60 min by using a pressure cooker, and airing to dry to obtain aseptic raw materials; and preparing the traditional Chinese medicine preparation from the obtained aseptic raw materials. The traditional Chinese medicine preparation has the efficacy of clearing dryness to moisten lung, diffusing the lung and dispersing the pathogen, and diminishing the inflammation and relieving pain, and is used to treat atrophic rhinitis.

Description

The Chinese medicine preparation of atrophic rhinitis

Technical field

The present invention relates to field of traditional Chinese; Be specifically related to a kind of Chinese medicine preparation of atrophic rhinitis.

Background technology

Atrophic rhinitis is a kind of nasal cavity chronic inflammatory disease of slower development, and morbidity has provincialism.Primary disease female patient is more, is mainly in person between twenty and fifty, and health status and person in dreadful conditions of life easily suffer from this disease, presents in recent years the trend reducing gradually.Be characterized in that nasal mucosa is dry, atrophy, nasal cavity increases, olfactory disorder, and nasal cavity has that a large amount of yellow green pus is silly to be formed, and primary disease can be divided into two kinds of former and secondary according to the cause of disease.Secondary atrophic rhinitis is due to chronic rhinosinusitis coexisting, nasal cavity specific infection, destructive stimulus gas as long-term in tuberculosis of nose, leprosy of nose etc. and occupation contacts, and mucosa destroys heavier, progressively, due to atrophy, be also found in nasal cavity Repeated Operation or perform the operation the too much patient of improper nasal cavity cutting tissue.Most of primary atrophic rhinitises are agnogenio, have following several theories: 1. A, B, B are deficient in vitamin ₂treatment primary disease, can achieve good results, therefore there is this to say.People's lives are improved in recent years, and domestic atrophic rhinitis's sickness rate greatly reduces, and only has more patient in certain areas.2. endocrine dysfunction, because primary disease often betides Puberty of Female, and increases the weight of in menstrual phase symptom, may be relevant with sex hormones secretion disorder.3. bacterial infectious hypothesis, can turn out diphtheroid, abel's bacillus, Bacillus proteus etc. in this patient nasal discharge, therefore there is this theory.But most scholars find not cause primary disease with these microbionation tests.4. whether sheerly theory of heredity, find that one family, may be relevant with identical living condition and environment with suffering from primary disease, hereditary, still absence of proof sometimes.5. immunological theory, Recent study finds that this patient has immunologic function disorder mostly, may be a kind of autoimmune disease therefore propose primary disease.The other medicines for the treatment of this disease in prior art exist therapeutic effect not obvious, the technological deficiency that side effect is large.

Summary of the invention

The object of the present invention is to provide a kind of Chinese medicine preparation with clearing away dryness lung moistening, the loose heresy of lung qi dispersing, anti-inflammatory analgetic effect, be used for the treatment of atrophic rhinitis.

Technical scheme of the present invention: the raw material of Chinese medicine preparation of the present invention and each component consumption thereof are groped in a large number to sum up through inventor and drawn, each component amount all has good effect within the scope of this: 15 parts, Folium Mori, 30 parts of Radix Adenophorae (Radix Glehniae), 30 parts of Gypsum Fibrosum, 12 parts of Radix Ophiopogonis, 12 parts of Herba Dendrobiis, 12 parts, Colla Corii Asini, 10 parts, Semen Armeniacae Amarum, 15 parts of Fructus Cannabis, 10 parts of Radix Scutellariaes.

For reaching clearing away dryness lung moistening, loose evil, the anti-inflammatory analgetic effect of lung qi dispersing, the present invention selects 10 parts, 15 parts, Folium Mori, 30 parts of Radix Adenophorae (Radix Glehniae), 30 parts of Gypsum Fibrosum, 12 parts of Radix Ophiopogonis, 12 parts of Herba Dendrobiis, 12 parts, Colla Corii Asini, 10 parts, Semen Armeniacae Amarum, 15 parts of Fructus Cannabis, Radix Scutellariae to combine, by these drug regimens, make each efficacy of drugs produce synergism, thus effective atrophic rhinitis.In the raw materials of traditional Chinese medicinal materials of choosing, its effect and pharmacological action respectively:

Folium Mori: Folium Mori are dried leaves of moraceae plants Mulberry, have another name called a Mulberry, Jing Sang, Fructus Mori tree, yellow wood etc., and there is production national most areas more, has the effects such as blood pressure lowering, blood fat, antiinflammatory; Being rich in rare element organic selenium, germanium, is natural powerful antioxidant, can remove interior free yl, makes to be accumulated in toxin and refuse in human body oxidized, increases the oxygen content in blood, enhances metabolism and microcirculation.There is extraordinary assosting effect for the treatment of hyperlipidemia, hyperglycemia, fatty liver, coronary heart disease, hypertension, first, hepatitis B and the postoperative chemicotherapy patient's of cancer rehabilitation.Effect: dispelling wind and heat pathogens; Lung heat clearing; Improving eyesight.Main anemopyretic cold; Pathogenic wind-warm is from the beginning of, fever and headache, perspiration and aversion to wind, cough chest pain; Or dryness of the lung dry cough without phlegm; Dry throat and mouth; On wind heat and liver-yang, disturb; Conjunctival congestion and swelling pain.For anemopyretic cold, lung-heat type cough, dizziness headache, conjunctival congestion is dim-sighted.

Radix Adenophorae (Radix Glehniae): Radix Adenophorae (Radix Glehniae), another name Radix Adenophorae, bubble ginseng, bubble Radix Adenophorae (Radix Glehniae), for campanulaceae Lady bell plant four leaf Radix Adenophorae (Radix Glehniae) Adenophora tetraphylla (Thunb.) Fisch.A.berticillata (Pall.) Fisch., Folium Pruni Radix Adenophorae (Radix Glehniae) A.axilliflora Borb A.stricta Miq. or its congener, be used as medicine with root.Autumn, plane was adopted, and removed aerial parts and fibrous root, scraped off rough bark, immediately dried.Clearing away heat and nourishing YIN, nourishing the lung to arrest cough.Cure mainly tracheitis, pertussis, cough due to lung-heat, coughs up phlegm yellow thick.

Gypsum Fibrosum: Gypsum Fibrosum is calcium sulphate dihydrate (Ca (SO4) 2H2O), claims again dihydrate gypsum, water stone cream or soft gypsum, theoretical composition CaO32.6%, SO346.5%, H2O+20.9%, monoclinic system, crystal is tabular, conventionally be compact massive or fibrous, white or grey, red, brown, glass or silky luster, mohs hardness is 2, cleavage is parallel, and { 010} is complete, density 2.3g/cm3; [curing mainly] apoplexy cold and heat, heart subinverse gas is frightened to be breathed heavily, and xerostomia scorching tongue, can not cease, hardness and fullness in the abdomen pain, evil removing ghost, puerperium incised wound.Except seasonal epidemic pathogens headache fever of the body, the large heat of three warmers, skin heat, stagnation of QI in the intestines and stomach, expelling pathogenic factors from muscles by diaphoresis, the restlessness accompanied by ascending of QI of only quenching one's thirst, the sudden and violent gas of abdominal distention, the pharynx heat of panting, also can do bath soup.Cure the wound cold headache as split.Simmer tea with Herba Alii fistulosi, the pain of decaptitating.Control day row fanatic, wind syndrome of head revolves, and stimulating milk secretion is wiped tooth benefit tooth.Except gastric heat lung-heat, loose YIN pathogen, slow spleen QI invigorating.Only Yangming Channel headache, fever with chills, day food in one's mouth hectic fever, drinking a large amount of water due to extreme thirst, heatstroke hectic fever, has a toothache.

Radix Ophiopogonis: [effect] nourishing YIN and moistening the lung; Reinforcing stomach reg fluid; Relieving restlessness clears away heart-fire.Dryness of the lung dry cough, spits blood, spitting of blood, and consumptive lung disease, lung abscess, asthenia dysphoria with smothery sensation, quenches one's thirst, calentura Tianjin wound, dry mouth and throat, constipation.[curing mainly]: dryness of the lung dry cough; Spit blood; Spitting of blood; Consumptive lung disease; Lung abscess; Deficiency of YIN chronic cough; Tianjin wound is thirsty; Quench one's thirst; Calentura Tianjin wound; Vexed insomnia; Have sore throat; Dryness of the intestine constipation; Heat in blood is told nosebleed." book on Chinese herbal medicine converges and says ": Radix Ophiopogonis, the medicine of clearing away heart-fire and moistening the lung also.Main deficiency of heart-QI, palpitation with fear palpitation with a distress feeling, forgetful in a trance, spirit fall; Or the lung-heat dryness of the lung, cough sound running fire, consumptive lung disease leaf scorch, the dyspnea due to deficiency of losing heart, in fire volt lung, spitting of blood hemoptysis; Or asthenia exopathogenic heat, body fluid is dry few; Or taste are dry dries up, constipation due to insufficiency dyschezia; All the strongly fragrant card of cardiopulmonary kidney spleen unit asthenic fire is also for this.But sweet in the mouth gas is flat, energy lung benefiting gold, bitter in the mouth is cold in nature, can fall heart-fire, and body profit matter is mended, and can support medulla renis, and the merit of specially controlling strain deficiency-heat is in the majority.

Herba Dendrobii: all kinds of Herba Dendrobii goods.Comprise: Herba Dendrobii, Tongpi Fendou, HERBA DENDROBII etc.Herba Dendrobii is one of orchid of recording the earliest during China's ancient Chinese prose is offered.Its nature and flavor: sweet light micro-salty.Property belong to clear and rich, have benefit in clear, invigorating middle warmer has clearly.Function cures mainly: reinforcing stomach reg fluid, nourishing YIN and clearing away heat.Lose for cloudy impairment of body fluid, xerostomia excessive thirst, lack of appetite is retched, deficiency-heat after being ill, poor vision.

Colla Corii Asini: boil the glue forming after the skin unhairing of equine species donkey Equus asinus Linnaeus.The YIN nourishing of enriching blood, moisturizes, hemostasis.For blood deficiency and yellow complexion, dizzy cardiopalmus, dysphoria and insomnia, xeropulmonary cough.

Semen Armeniacae Amarum: be rosaceous plant Prunus armeniaca L.var.ansu Maxim., the mature fruit of gathering summer, removes sarcocarp and nucleocapsid, takes out seed, dries.Another name: Semen Armeniacae Amarum.Containing amygdalin (amygdalin) approximately 3%, fatty oil approximately 50%, and containing emulsin (emulsin), amygdalase (amygdalase), prunase (prunase), oxynitrilase (oxynitrilase), and soluble protein. placement adds water after seed grinding, amygdalin is subject to the effect of emulsin, generates hydrocyanic acid, benzaldehyde and glucose.Cure mainly function and have sending down the abnormal ascending QI relieving cough and asthma, loosening bowel to relieve constipation.For cough and asthma, fullness in the chest abundant expectoration, blood deficiency Tianjin is withered, dryness of the intestine constipation.[meridian distribution of property and flavor] is bitter, tepor, slightly poisonous.Return liver, large intestine channel.

Fructus Cannabis is exactly the fruit shelling.The core of cannabis seeds, can extract oil, and hyoscine is again aperient.Nature and flavor: sweet in the mouth, property is flat, nontoxic.Effect: mainly can invigorating the spleen and replenishing QI.Take for a long time, make light of one's life by commiting suicide healthy strong, just as angle.It can be controlled apoplexy and perspire, harnesses the river swollen, and diuresis, removing mass blood, dredging blood vessel, controls women's disease in puerperal.With it carry out wash my hair, can hair growth promoting hair care.It is fried after perfume (or spice), soak with urine, after being twisted into, take, can make people happy.Anemia of pregnant woman's malpresentation, swallows 27 pieces of Fructus Cannabis and can produce.Can also moisten the five internal organs, control heat of the large intestine.Constipation.Man eats many, meeting spermatorrhea, sexual impotence.Women overeats, and causes that leucorrhea is undesired at once.

Radix Scutellariae: Radix Scutellariae another name Radix Scutellariae, tsuchikane tea root.For labiate Radix Scutellariae (Scutellaria baicalensis Georgi), be used as medicine with root.Have heat clearing and damp drying, removing heat from blood is antiabortive, detoxicating functions.Cure mainly the diseases such as epidemic febrile disease, upper respiratory tract infection, cough due to lung-heat, damp and hot jaundice, pneumonia, dysentery, hemoptysis, conjunctival congestion, frequent fetal movement, hypertension, carbuncle furuncle.The clinical practice of Radix Scutellariae is antibacterial not worse than Rhizoma Coptidis, and does not develop immunity to drugs.We are used in fungal culture miscellaneous bacteria and infect special severity by the strong feature of broad-spectrum antibacterial action, and fine by Radix Scutellariae extracting solution effect, it is that agricultural disease is prevented and treated optimal Herba indigoferae Pseudotinctoriae.

For Da Gengjia result of use, the present invention also provides the preparation method of this Chinese medicine preparation; Its preparation method: take 10 parts, 15 parts, raw material Folium Mori, 30 parts of Radix Adenophorae (Radix Glehniae), 30 parts of Gypsum Fibrosum, 12 parts of Radix Ophiopogonis, 12 parts of Herba Dendrobiis, 12 parts, Colla Corii Asini, 10 parts, Semen Armeniacae Amarum, 15 parts of Fructus Cannabis, Radix Scutellariae and make respectively decoction pieces, through pressure cooker cooking disinfection 30-60 minute, dry, obtain aseptic raw material; The aseptic raw material obtaining is made Chinese medicine preparation.

Chinese medicine for outer use of the present invention has clearing away dryness lung moistening, loose evil, the anti-inflammatory analgetic effect of lung qi dispersing, is used for the treatment of atrophic rhinitis.So far, still do not find report and the application about Chinese medicine preparation of the present invention.The inventor, through research repeatedly, and by the checking repeatedly of clinical trial, has finally found the Chinese medicine preparation that has better curative effect, thereby has completed the present invention.

Specific implementation method

Atrophic rhinitis of the present invention, its raw material is: 15 parts, Folium Mori, 30 parts of Radix Adenophorae (Radix Glehniae), 30 parts of Gypsum Fibrosum, 12 parts of Radix Ophiopogonis, 12 parts of Herba Dendrobiis, 12 parts, Colla Corii Asini, 10 parts, Semen Armeniacae Amarum, 15 parts of Fructus Cannabis, 10 parts of Radix Scutellariaes.

Its preparation method: take 10 parts, 15 parts, raw material Folium Mori, 30 parts of Radix Adenophorae (Radix Glehniae), 30 parts of Gypsum Fibrosum, 12 parts of Radix Ophiopogonis, 12 parts of Herba Dendrobiis, 12 parts, Colla Corii Asini, 10 parts, Semen Armeniacae Amarum, 15 parts of Fructus Cannabis, Radix Scutellariae and make respectively decoction pieces, through pressure cooker cooking disinfection 30-60 minute, dry, obtain aseptic raw material; The aseptic raw material obtaining is made Chinese medicine preparation.

Claims (2)

1. a Chinese medicine preparation for atrophic rhinitis, is characterized in that: its raw material is; 15 parts, Folium Mori, 30 parts of Radix Adenophorae (Radix Glehniae), 30 parts of Gypsum Fibrosum, 12 parts of Radix Ophiopogonis, 12 parts of Herba Dendrobiis, 12 parts, Colla Corii Asini, 10 parts, Semen Armeniacae Amarum, 15 parts of Fructus Cannabis, 10 parts of Radix Scutellariaes.

2. according to the Chinese medicine preparation of atrophic rhinitis claimed in claim 1, it is characterized in that: its preparation method: take 10 parts, 15 parts, raw material Folium Mori, 30 parts of Radix Adenophorae (Radix Glehniae), 30 parts of Gypsum Fibrosum, 12 parts of Radix Ophiopogonis, 12 parts of Herba Dendrobiis, 12 parts, Colla Corii Asini, 10 parts, Semen Armeniacae Amarum, 15 parts of Fructus Cannabis, Radix Scutellariae and make respectively decoction pieces, through pressure cooker cooking disinfection 30-60 minute, dry, obtain aseptic raw material; The aseptic raw material obtaining is made Chinese medicine preparation.