CN104055979A - Chinese herb preparation for treating liver and gall damp-heat type chronic pancreatitis - Google Patents
Chinese herb preparation for treating liver and gall damp-heat type chronic pancreatitis Download PDFInfo
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- CN104055979A CN104055979A CN201410318235.5A CN201410318235A CN104055979A CN 104055979 A CN104055979 A CN 104055979A CN 201410318235 A CN201410318235 A CN 201410318235A CN 104055979 A CN104055979 A CN 104055979A
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Abstract
The invention discloses a Chinese herb preparation for treating the liver and gall damp-heat type chronic pancreatitis. The chronic pancreatitis belongs to the scope of gastral cavity pains, abdominal pains and hypochondriac pains in the traditional Chinese medicine. The pathogenesis of the chronic pancreatitis is that exogenous pathogenic factors generate heat to invade the interior or the diet of a person is disorder, so that damp heat is accumulated to the liver and the gall, and catharsis cannot be achieved. Traditional Chinese medicine including butterflybush flowers, smallflower galinsoga flowers, nomame senna herbs, hypoglauca diels, puberulous glochidion branchlet and leaves, huperzia serrata, small-leaved desmodium roots, swertia mileensis, swertia punicea, primula malacoides, pinellia cordata and acid fujiki which have the effects of refreshing the liver and the gall, removing the damp heat and relieving the pains are selected for preparing the Chinese herb preparation, and the traditional Chinese medicine is decocted with water to form decoctions. Clinical tests in the hospital show that the total effective rate is 83.3%, the treatment effect is remarkable, the total effective rate of the Chinese herb preparation is obviously better than the total effective rates of control groups, the treatment cost is low, the method is easy and convenient to use, and the Chinese herb preparation is worthy of application and popularization in clinic.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, relate in particular to a kind of Chinese medicine preparation for the treatment of liver gallbladder damp-heat type chronic pancreatitis.
Background technology
Chronic pancreatitis refers to that pancreas shows effect repeatedly or persistence inflammatory disorders, pancreatic cell is organized gradually and by fibrous tissue, replaced.Often with calcification, pseudocyst and islet cells, reduce or atrophy, make pancreatic function heavy damage, cause the obvious obstacle of digestive system.The traditional Chinese medical science is thought many and is caused by eating and drinking without temperance, eating and drinking too much at one meal or excessive drinking.Main manifestations is repeatedly the upper abdominal pain of outbreak, and while increasing the weight of, with nausea and vomiting, after feed greasy food, Abdeminal pain does not relax, suffers from diarrhoea and become thin.Be more common in 40 years old above person, male is more than women, and the course of disease reaches several years or 10 She's years.The treatment of doctor trained in Western medicine to primary disease at present, adopt kept on a diet more, application pancreatin and analgesic treatments, or operative treatment, how undesirable effect is; Chinese medicine has greater advance in chronic pancreatitis aspect preventing and treating in recent years, Chinese traditional treatment is started with from pathogenesis, adopt the method for wholistic therapy, rationally Selection drug, adopts and has liver heat removing gallbladder, and dialectical the executing of Chinese medicine of the effects such as dampness removing heat cured treatment liver gallbladder damp-heat type chronic pancreatitis, treating both the principal and secondary aspects of a disease, effect is remarkable, and relapse rate is low, and toxic and side effects is little.
Summary of the invention
The object of this invention is to provide a kind of Chinese medicine preparation for the treatment of liver gallbladder damp-heat type chronic pancreatitis.The pathogenesis of liver gallbladder damp-heat type chronic pancreatitis be in exopathogen, invade or diet uncomfortable so that damp and hot heresy pents up in liver and gall, and it is lost in free flow of qi.Chronic pancreatitis belongs to Chinese medicine " gastric abscess ", " stomachache " and " hypochondriac pain " category.Control suitable liver heat removing gallbladder, dampness removing heat, pain relieves the pain.
The object of the invention is to be achieved through the following technical solutions, the Chinese medicine preparation of this treatment liver gallbladder damp-heat type chronic pancreatitis is made by the Chinese medicine of following weight portion: Flos Buddlejae 3-6 part, Flos Galinsogae Parviflorae 9-12 part, Herba Cassiae Nomamis 9-15 part, Radix cycleae hypoglaucae 5-9 part, Folium glochidionis puberi 15-25 part, Herba Lycopodii serrati 15-25 part, Radix desmodiik microphylli 10-20 part, Herba Swertiae Mileensis 9-15 part, Herba Swertiae Puniceae 25-30 part, Flos Primulae Vittatae 3-6 part, Rhizoma pinelliae cordatae 1-3 part, Radix embeliae laetae 5-10 part.
Preferably, 4 parts of Flos Buddlejaes, 10 parts of Flos Galinsogae Parvifloraes, 12 parts of Herba Cassiae Nomamis, 7 parts of Radix cycleae hypoglaucaes, 20 parts of Folium glochidionis puberi, 20 parts of Herba Lycopodii serratis, 15 parts of Radix desmodiik microphyllis, 12 parts of Herba Swertiae Mileensises, 27 parts of Herba Swertiae Puniceae, 4 parts of Flos Primulae Vittatae, 2 parts of Rhizoma pinelliae cordatae, 7 parts of Radix embeliae laetae.
Preparation method is made decoction by above-mentioned Chinese medicine decocting.
In side: Flos Buddlejae liver heat removing and eyesight improving, nebula removing, removing heat from blood dispels the wind; Flos Galinsogae Parviflorae liver heat removing and eyesight improving; Herba Cassiae Nomamis liver heat removing and eyesight improving, diuretic and spleen; Radix cycleae hypoglaucae removing fire from the liver, relieving heat toxin, antiinflammatory; Folium glochidionis puberi clearing away heat-damp and promoting diuresis, removing toxic substances and promoting subsidence of swelling; Herba Lycopodii serrati is brought down a fever, dehumidifying, repercussive, hemostasis; Radix desmodiik microphylli clearing away heat-damp and promoting diuresis, hemostasis, dredging collateral; The clear dampness-heat in the liver and gallbladder of Herba Swertiae Mileensis, except fire stomach second of the three ten-day periods of the hot season; Herba Swertiae Puniceae heat clearing and damp drying, eliminating pathogen in the liver function of gallbladder promoting; Flos Primulae Vittatae heat clearing and damp drying, eliminating pathogen in the liver gallbladder fire, hemostasis; Rhizoma pinelliae cordatae eliminating stasis to stop pain, subduing swelling and detoxicating; Radix embeliae laetae eliminating stasis to stop pain, antiinflammatory.
Clinical data
1, the routine patient of physical data 72 all meets the diagnostic criteria of liver gallbladder damp-heat type chronic pancreatitis, is divided at random each 36 examples for the treatment of group and matched group.Treatment group: male 22 examples, female's 14 examples, 24～56 years old age, average 44.6 years old, the course of disease 1.5 years～7 years.Matched group man 23 examples, female's 13 examples, the age is 25～55 years old, average 45.1 years old, the course of disease 1.5 years～7 years.Two groups at aspects such as sex, age, the course of disease, the state of an illness without significant difference (P > 0.05), there is comparability.
2, the clinical card of diagnostic criteria is shown in: gastral cavilty, pain in the hypochondrium, anorexia are greasy, heating, feel sick, heavy sensation of the body asthenia or jaundice.Yellowish fur, slippery and rapid pulse.Clinical diagnosis: (1) x-ray inspection finds that pancreas has calcification or calculus, cyst etc. really; (2) biliary tract or the infringement of pancreas essence radiography indicating characteristic; (3) upper abdominal pain, tenderness continues more than 6 months; (4) pancreas secretory function test abnormality.
3, Therapeutic Method treatment group is taken Chinese medicine preparation of the present invention, take Flos Buddlejae 4g, Flos Galinsogae Parviflorae 10g, Herba Cassiae Nomamis 12g, Radix cycleae hypoglaucae 7g, Folium glochidionis puberi 20g, Herba Lycopodii serrati 20g, Radix desmodiik microphylli 15g, Herba Swertiae Mileensis 12g, Herba Swertiae Puniceae 27g, Flos Primulae Vittatae 4g, Rhizoma pinelliae cordatae 2g, Radix embeliae laetae 7g, decocting becomes decoction, potion, divided and sooner or later took for 2 times every day.Matched group adopts western medicine, the each 0.2g of antibiotic ciprofloxacin injection, intravenous injection in 12 hours 1 time; 5% glucose injection 300ml adds cimetidine 0.6g, 1 intravenous drip every day.30 days each courses for the treatment of, add up curative effect after all treating 2 courses for the treatment of for two groups.
4, criterion of therapeutical effect is cured substantially: colic symptoms disappears.Effective: colic symptoms disappears substantially, outbreak in 1 month is no more than 3 times.Invalid: unchanged before and after colic symptoms and attack times medication.
5, curative effect comparison after 2 courses for the treatment of of two groups of therapeutic outcomes treatment, treatment group 36 examples, wherein cure 14 examples (38.9%) substantially, effective 16 examples (44.4%), invalid 6 examples (16.7%), total effective rate 83.3%; Matched group 36 examples, wherein cure 9 examples (25%) substantially, effective 11 examples (30.6%), invalid 16 examples (44.4%), total effective rate 55.5%.Two groups of comparisons, treatment group cure rate, total effective rate are obviously better than matched group, have comparability (P < 0.05).
The specific embodiment
Embodiment mono-: take Flos Buddlejae 4g, Flos Galinsogae Parviflorae 10g, Herba Cassiae Nomamis 12g, Radix cycleae hypoglaucae 7g, Folium glochidionis puberi 20g, Herba Lycopodii serrati 20g, Radix desmodiik microphylli 15g, Herba Swertiae Mileensis 12g, Herba Swertiae Puniceae 27g, Flos Primulae Vittatae 4g, Rhizoma pinelliae cordatae 2g, Radix embeliae laetae 7g, above-mentioned Chinese medicine decocting is become to decoction.
Embodiment bis-: take Flos Buddlejae 3g, Flos Galinsogae Parviflorae 12g, Herba Cassiae Nomamis 9g, Radix cycleae hypoglaucae 9g, Folium glochidionis puberi 15g, Herba Lycopodii serrati 25g, Radix desmodiik microphylli 10g, Herba Swertiae Mileensis 15g, Herba Swertiae Puniceae 25g, Flos Primulae Vittatae 6g, Rhizoma pinelliae cordatae 1g, Radix embeliae laetae 10g, above-mentioned Chinese medicine decocting is become to decoction.
Embodiment tri-: take Flos Buddlejae 6g, Flos Galinsogae Parviflorae 9g, Herba Cassiae Nomamis 15g, Radix cycleae hypoglaucae 5g, Folium glochidionis puberi 25g, Herba Lycopodii serrati 15g, Radix desmodiik microphylli 20g, Herba Swertiae Mileensis 9g, Herba Swertiae Puniceae 30g, Flos Primulae Vittatae 3g, Rhizoma pinelliae cordatae 3g, Radix embeliae laetae 5g, above-mentioned Chinese medicine decocting is become to decoction.
Claims (2)
1. treat a Chinese medicine preparation for liver gallbladder damp-heat type chronic pancreatitis, it is characterized in that this Chinese medicine preparation made by the Chinese medicine of following weight portion: Flos Buddlejae 3-6 part, Flos Galinsogae Parviflorae 9-12 part, Herba Cassiae Nomamis 9-15 part, Radix cycleae hypoglaucae 5-9 part, Folium glochidionis puberi 15-25 part, Herba Lycopodii serrati 15-25 part, Radix desmodiik microphylli 10-20 part, Herba Swertiae Mileensis 9-15 part, Herba Swertiae Puniceae 25-30 part, Flos Primulae Vittatae 3-6 part, Rhizoma pinelliae cordatae 1-3 part, Radix embeliae laetae 5-10 part.
2. a kind of Chinese medicine preparation for the treatment of liver gallbladder damp-heat type chronic pancreatitis according to claim 1, is characterized in that this Chinese medicine preparation made by the Chinese medicine of following weight portion: 4 parts of Flos Buddlejaes, 10 parts of Flos Galinsogae Parvifloraes, 12 parts of Herba Cassiae Nomamis, 7 parts of Radix cycleae hypoglaucaes, 20 parts of Folium glochidionis puberi, 20 parts of Herba Lycopodii serratis, 15 parts of Radix desmodiik microphyllis, 12 parts of Herba Swertiae Mileensises, 27 parts of Herba Swertiae Puniceae, 4 parts of Flos Primulae Vittatae, 2 parts of Rhizoma pinelliae cordatae, 7 parts of Radix embeliae laetae.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105169210A (en) * | 2015-10-26 | 2015-12-23 | 烟台瑞智生物医药科技有限公司 | Traditional Chinese medicinal composition for treating hypochondriac pain due to damp-heat in liver and gallbladder |
Citations (5)
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| CN1943760A (en) * | 2005-12-05 | 2007-04-11 | 李宝德 | A Chinese traditional medicine for treatment of pancreatitis |
| EP2412377A1 (en) * | 2009-03-27 | 2012-02-01 | Kracie Pharma, Ltd. | Burdock fruit extract containing arctigenin at high content and process for producing same |
| CN103340990A (en) * | 2013-07-22 | 2013-10-09 | 张海英 | Traditional Chinese medicine for treating pancreatitis and preparation method thereof |
| CN103393899A (en) * | 2013-07-20 | 2013-11-20 | 程霞 | Traditional Chinese medicine composition for treating acute pancreatitis |
| CN103463439A (en) * | 2013-08-19 | 2013-12-25 | 韩其厚 | Chinese herbal preparation for treating severe acute pancreatitis |
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2014
- 2014-06-26 CN CN201410318235.5A patent/CN104055979A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1943760A (en) * | 2005-12-05 | 2007-04-11 | 李宝德 | A Chinese traditional medicine for treatment of pancreatitis |
| EP2412377A1 (en) * | 2009-03-27 | 2012-02-01 | Kracie Pharma, Ltd. | Burdock fruit extract containing arctigenin at high content and process for producing same |
| CN103393899A (en) * | 2013-07-20 | 2013-11-20 | 程霞 | Traditional Chinese medicine composition for treating acute pancreatitis |
| CN103340990A (en) * | 2013-07-22 | 2013-10-09 | 张海英 | Traditional Chinese medicine for treating pancreatitis and preparation method thereof |
| CN103463439A (en) * | 2013-08-19 | 2013-12-25 | 韩其厚 | Chinese herbal preparation for treating severe acute pancreatitis |
Non-Patent Citations (2)
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| 王喜媚: "慢性胰腺炎的中医辨治", 《时珍国医国药》 * |
| 邓向林: "胰腺炎辨证论治的体会", 《河北中医》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105169210A (en) * | 2015-10-26 | 2015-12-23 | 烟台瑞智生物医药科技有限公司 | Traditional Chinese medicinal composition for treating hypochondriac pain due to damp-heat in liver and gallbladder |
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Application publication date: 20140924 |
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